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Query: 3dde_A mol:protein length:239 TENA/THI-4 protein, Domain of Unknown Function with a Heme Oxygenase-like Fold, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst GMSIIDLTKLEQKVATMWDSILTNSPFIHEVLDGKATKALYAIYMTETYHYTKHNAKNQALVGIMGKDLPGKYLSFCFHHAHEEAGHELMALSDIASIGFDREDVLSSKPLPATETLIAYLYWISATGNPVQRLGYSYWAENVYGYIDPVLKAIQSTLDLTPQSMKFFIAHSKIDAKHAEEVNEMLHEVCKTQEDVDSVVAVMENSLVLTARILDDVWKEYQLFQSGASDRYAFLRDNALast
1 -98.0003dde_A mol:protein length:239 TENA/THI-4 protein, Domain of Unknown Function with a Heme Oxygenase-like Fold  ali model  100  1GMSIIDLTKLEQKVATMWDSILTNSPFIHEVLDGKATKALYAIYMTETYHYTKHNAKNQALVGIMGKDLPGKYLSFCFHHAHEEAGHELMALSDIASIGFDREDVLSSKPLPATETLIAYLYWISATGNPVQRLGYSYWAENVYGYIDPVLKAIQSTLDLTPQSMKFFIAHSKIDAKHAEEVNEMLHEVCKTQEDVDSVVAVMENSLVLTARILDDVWKEYQLFQSGASDRYAFLRDNA 239
2 -66.5003oql_A mol:protein length:262 TenA homolog  ali model follow..  12  1GMIDAWAQQLINDCSPAKAR-VVEHELYQQMRDAKLSPQIMRQYLIGGWPVVEQFAVYMAKNLTKTRFGRHPARRWLMRNIRVELNHADYWVNWCAAHDVTLEDLHDQRVAPELHALSHWCWQTSSSDSLAVAMAATYAIEGATGECSTGVYAEAFAEETRKKSMKWLKMHAQYDDAHPWEALEIICTLVGSLQLQAELRQAVTKSYDYMYLFLERCIQLDKVKSPRGRVAALEM.... 262
3 -63.8001rcw_A mol:protein length:231 CT610  ali model follow..  15  1.MMEVFMNFLDQLDLIIQNKHMLEHTFYVKWSKGELTKEQLQAYAKDYYLHIKAFPKYLSAIHSRCDDLEARLLDNLMDEENGYPNHIDLWKQFVFALGVTPEELEAHEPSEAAKAKVATFMRWCTGDSLAAGVAALYSYESQIPRIREKIRGLTEYFGFNPEDYAYFTEHEEADVRHAREEKALIEMLL--KDDADKVLEASQEVTQSLYGFLDSFLDPGTCCSCHQS.......... 230
4 -62.6004wwj_A mol:protein length:263 TENA/THI-4 family protein  ali model follow..  12  19..YPAWTQQLIQDCSESKRR-VVEHELYQRMRDNKLSAKVMRQYLIGGWPVVEQFALYMAQNLTKTRFARHPARRWLMRNIRVELNHADYWVHWSRAHGVTLEDLQAQQVPPELHALSHWCWHTSSADSLIVAIAATYAIEGATGEWSALVCSNGIYAEDRKRAMKWLKMHAQYDDAHPWEALEIIVTLAPTKALQAELRQAICKSYDYMYLFLERCMQQEK---AVTRERLALAEG.. 263
5 -61.6001otv_A mol:protein length:259 Coenzyme PQQ synthesis protein C  ali model follow..  14  1.MLITDTQAFEEALRAKGDFYHIHHPYHIAMHNGDATRKQIQGWVANRFYYQTTIPLKDAAIMANCPDAQ--TRRKWVQRILDHDGGIEAWLRLGEAVGLSRDDLLSEHVLPGVRFAVDAYLNFARRACWQEAACSSLTELFAPQIHQSRLDSWPQHYPIKEEGYFYFRSRLSQANRDVEHGLALAKAYCDSAEKQNRMLEILQFKLDILWSMLDAMTMAYALQR.............. 233
6 -61.6003hlx_A mol:protein length:258 Pyrroloquinoline-quinone synthase  ali model follow..  14  1.MLITDTQAFEEALRAKGDFYHIHHPYHIAMHNGNATREQIQGWVANRFYYQTTIPLKDAAIMANCPDAQ--TRRKWVQRILDHDGGIEAWLRLGEAVGLSRDDLLSEHVLPGVRFAVDAYLNFARRACWQEAACSSLTELFAPQIHQSRLDSWPQHYPIKEEGYFFFRSRLSQANRDVEHGLALAKAYCDSAEKQNRMLEILQFKLDILWSMLDAMTMAYALQRHTVTDKAAWHTTR. 249
7 -60.7004lqx_A mol:protein length:322 TENA/THI-4 domain-containing protein  ali model follow..  17  74.TPNSLSMWIRTRFIERFYG-DNPHPFIVAM--QNPTKGVLLGYVIEHQHFLKNWVKVLSSIVFKTDKDD--VLQYELENISVEFIHYELLLRMGEALGMPREKILSTQPLPSTQSAIKTWRKIAESKTWLETMASMHSLELVADRSLVKYPEILSSDEYPQAVKDFLREGYEADVSHAGEALEMVEKYTEEMEMKEQVQITVLKSFDAFSKYLLARLERGFEIEPSLLKRVI...... 315
8 -53.6003bjd_A mol:protein length:332 Putative 3-oxoacyl-(acyl-carrier-protein) synthase  ali model follow..  13  107..EEDFQKRLEQEIA---AQSRERHPMSQYVFSGSASRAQLQVFLRHQWFRTFRLYRDAADLLVNLTDVD--EAAALARYLYGELGHPRLLAKLLEAIGLE-ADFQAVSTMPEEIAYLNNRARAFRHAEVGWGLAVFYITELVVPGNHEKLYRALLQAGLSEDQAEYYKVHISLVPPRAKREWQLIARRIPDVQFQNAFLTSLSQHFRVERAYYDAIWEEMQSVKGS............ 332
9 -52.4005vrd_D mol:protein length:392 Bifunctional coenzyme PQQ synthesis protein C/D  ali model follow..  15  33..HEELEAALRDIGA---RRYHNLHPFHRLLHDGKLSKDQVRAWALNRYYYQAMIPVKDAALLARLPDAQ--LRRIWRQRIVDHDGGIERWLKLAEGVGFTRDYVLSTKGLSATRFSVDAYVHFVSERSLLEAIASSLTEMFSPTIISERVAGMLKNYDITKDTLAYFDKRLTQAPRDADFALDYVKRHATTPEMQRAAIDALTFKCNVLWTQLDALYFAYVAPGMVPPDAWQ...... 266
10 -46.6003b5o_A mol:protein length:244 CADD-like protein of unknown function  ali model follow..  16  1GMEFNHLKQLNQLLAQDYVASITENPVVQML--SQASFAQIAYVMQQYSIFPKELVGFTELARRKALGAGNGVAQELQENIDEEMGHYTLLADGLEELGV---AVKNTMPSVATSKLLRTVLSLFDR-QVDYVLGATYAIEATSIPELTLIVKLVEWLAIPKDLQYFFSKHDEWEIEHEAGLRTSVAAYI-QPEEFGEFAAGFRAMIDAMQVWWQELAQEAISSEVVLSTAIA...... 241
11 -43.8002gm7_A mol:protein length:221 tenA homolog/Thi-4 Thiaminase  ali model follow..  12  1.MALGVTGELRRRADGIWQR-ILAHPFVAELYAGTLPMEKFKYYLLQDYNYLVNFAKALSLAASRAPSVDLMALELAYGTVTGEM---ANYEALLKEVGLSLRDAAEAEPNRVNVSYMAYLKSTCALEGFYQCMAALLPCFWSYAEIAERHGGKLRENP-VHVYKKWASVYL--SPEYRGLVERLRAVLDSSGLSAEELWPYFKEASLYELEFWQAAYEG................... 214
12 -43.6001udd_A mol:protein length:226 transcriptional regulator  ali model follow..  10  1.MRVMITDKLRRDSEQIWKK-IFEHPFVVQLYSGTLPLEKFKFYVLQDFNYLVGLTRALAVISSKAEYPLM--AELIELARDEVTVEVENYVKLLKELDLTLEDAIKTEPTLVNSAYMDFMLATAYKGNIIEGLTALLPCFWSYAEIAEYHKDKLRDNP-IKIYREWGKVYLSNELNLVGRLRKIIDSS--GHSGYDRLRRIFITGSKFELAFWEMAWRG................... 214
13 -42.9003mvu_A mol:protein length:226 TenA family transcriptional regulator  ali model follow..  12  1GMSEKAFSLMRAEAEPAWRA-YTHHAFVEGLKAGTLPREAFLHYLQQDYVFLIHFSRAWALAVVKSETHSEMAVGTVNALVAEEM---QLHIGICEASGISQEALFATRERAENLAYTRFVLEAGYSGDLLDLLAALAPCVMGYGEIGKRLTAEAT----STLYGDWIDTYGGDDQAACKAVGTLLDDALESSPRWSRLCQTFHTATELEVGFWQMGLTP................... 226
14 -42.7001tyh_A mol:protein length:248 Transcriptional activator tenA  ali model follow..  16  1.MSLKFSEECRSAAAEWWEG-SFVHPFVQGIGDGTLPIDRFKYYVLQDSYYLTHFAKVQSFGAAYAKDLYTTMASHAQGTYEAEM---ALHREFAELLEISEEERKAFKPSPTAYSYTSHMYRSVLSGNFAEILAALLPCYWLYYEVGEKLLHCDPG---HPIYQKWIGTYGGDWRQQVEEQINRFDELAETEEVRAKMKENFVISSYYEYQFWGMAYRKEGWSDSAIKE......... 227
15 -42.6001z72_A mol:protein length:225 transcriptional regulator, putative  ali model follow..  15  13..PGLTVGELLKSSQKDWQA-AINHRFVKELFAGTIENKVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKFAKQLGFLEADED---GYFQKAFKELKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALPE----VYIHSEWINLHRGPFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDIGYD.................... 224
16 -42.4002a6b_A mol:protein length:234 hypothetical protein spr0628  ali model follow..  15  16..PGLTVGELLKSSQKDWQA-AINHRFVKELFAGTIENKVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKFAKQLGFLEADED---GYFQKAFKELKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALPE----VYIHSEWINLHRGPFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDIGYD.................... 227
17 -41.0002rd3_A mol:protein length:223 Transcriptional regulator  ali model follow..  12  5.FTMQVSQYLYQNAQSIWGD-CISHPFVQGIGRGTLERDKFRFYIIQDYLFLLEYAKVFALGVVKACDEAVMFSNAIQDILNNEM---SIHNHYIRELQITQKELQNACPTLANKSYTSYMLAEGFKGSIKEVAAAVLSCGWSYLVIAQNLSQIPNALE-HAFYGHWIKGYSSKEQACVNWNINLLDSLTLSKQEIEKLKEIFITTSEYEYLFWDMAYQS................... 223
18 -40.2001rtw_A mol:protein length:220 transcriptional activator, putative  ali model follow..  11  1....MFSEELIKENENIWRR-FLPHKFLIEMAENTIKKENFEKWLVNDYYFVKNALRFMALLMAKAPDDLLPFFAESIYYISKEL---EMFEKKAQELGISLNG----EIDWRAKSYVNYLLSVASLGSFLEGFTALYCEEKAYYEAWKWVRENLKE---RSPYQEFINHWSSQEGEYVKRIEKILNSLAEGEFEKERAREVFKEVSKFELIFWDIAYGG................... 208
19 -39.8002qzc_A mol:protein length:214 Transcriptional activator TenA-1  ali model follow..  10  1GMSVGNVENLINGVGELWNK-YVKHEFILKMRDGSLPLDIFRYYLIQDGKYVEDMLRALLIASSKGPIDKV--TKILNLVFSSRDKGLETHGKLYSKLDISRDVIVKTGYNLINYAYTRHLYYYA-NLDWNKFLVAWTPCMFGYSIVGDYVID-------NEVYKTWASFYASTE----KKRIEAILYALDEVSITEDLLNIFINSVRFEIGFWDASLRK................... 209
20 -39.1001to9_A mol:protein length:260 THI-4 protein  ali model follow..  15  18..AMKFSEECRSAAAEWWEG-SFVHPFVQGIGDGTLPIDRFKYYVLQDSYYLTHFAKVQSFGAAYAKDLYTTMASHAQGTYEAEM---ALHREFAELLEISEEERKAFKPSPTAYSYTSHMYRSVLSGNFAEILAALLPCYWLYYEVGEKLLHCDPG---HPIYQKWIGTYGGDWRQQVEEQINRFDELAETEEVRAKMKENFVISSYYEYQFWGMAYRKEGWSDSAIKE......... 243
21 -38.7004fn6_A mol:protein length:229 thiaminase-2  ali model follow..  11  1...MEFSQKLYQAAKPIIND-IYEDDFIQKMLLGNIQADALRHYLQADAAYLKEFTNLYALLIPKMNSMNDVLVEQIEFMVEGEV---LAHDILAQIVGESYEEIIKTKVPSGDHYIKHMYFQAHSRENAIYTIAAMAPCPYIYAELAKRSQSDHKLNR-EKDTAKWFDFYSTEMDDIINVFESLMNKLAESDKELEQVKQVFLESCIHERRFFNMAMTL................... 218
22 -38.5001yaf_A mol:protein length:263 Transcriptional activator tenA  ali model follow..  15  21..GMKFSEECRSAAAEWWEG-SFVHPFVQGIGDGTLPIDRFKYYVLQDSYYLTHFAKVQSFGAAYAKDLYTTMASHAQGTYEAEM---ALHREFAELLEISEEERKAFKPSPTAYSYTSHMYRSVLSGNFAEILAALLPCYWLYYEVGEKLLHCDPG---HPIYQKWIGTYGGDWRQQVEEQINRFDELAETEEVRAKMKENFVISSYYEYQFWGMAYRKEGWSDSAIKE......... 246
23 -37.5002f2g_A mol:protein length:221 SEED MATURATION PROTEIN PM36 HOMOLOG  ali model follow..  10  1.MERGVIDTWIDKHRSIYTA-ATRHAFVVSIRDGSVDLSSFRTWLGQDYLFVRRFVPFVASVLIRACKDSGSDMEVVLGGIASLNDEIEWFKR---EGSKWDVDFSTVVPQRANQEYGRFLEDLMSEVKYPVIMTAFWAIEAVYQESFAHCLE--DGNKTPVELTGACHRWGNDGKQYCSSVKNIAERCLESGEVLGEAEDVLVRVLELEVAFWEMSRGG................... 220
24 -36.9003no6_A mol:protein length:248 Transcriptional activator TenA  ali model follow..  12  13..GMTFSKELREASRPIIDD-IYNDGFIQDLLAGKLSNQAVRQYLRADASYLKEFTNIYAMLIPKMSSMEDVLVEQIEFMLEGEV---EAHEVLADFINEPYEEIVKEVWPPSGDHYIKHMYFNAARENAAFTIAAMAPCPYVYAVIGKRAMEDPKLNK-ESVTSKWFQFYSTEMDELVDVFDQLMDRLTKSETEKKEIKENFLQSTIHERHFFNMAYINEKWEYGGNNNE........ 242
25 -32.7002a2m_A mol:protein length:258 hypothetical protein BT3146  ali model follow..  10  41..ADSLFWKLWNGSLDTAVQVL-QTDYFKGIAAGTLDPNAYGSLMVQDGYYCFRGRDDYATAATCAQDET--LREFFKAKAKSYDEYNETYHQ-----TWHLREASGLIPGTDIKDYADYEAYVAGSLASPYMCVVMLPCEYLWPWIA---NFLDGYTPTNSLYRFWIEWNGG-TPNGAYQMGNMLEQYR-DKIDEDKAVEIFNTAMNYELKVFTSSTIL................... 245
26 -32.4001iw0_A mol:protein length:215 Heme oxygenase  ali model follow..  13  1.MTAGLAVELKQSTAQA-HEKAEHSTFMSDLLKGRLGVAEFTRLQEQAWLFYTALEQAVDAVRAS---------GFAESLLDPALNRAEVLARDLDKLNGSSEWRSRITASPAVIDYVNRLEEIRDNVDGPALVAHHYVRYLGDLSGGQVIARMQRHYGVDPEALGYHFEGIAKLKVYKDEYREKLNNLELSDEQREHLLKEATDAFVFNHQVFADLGKGL.................. 215
27 -28.0001wwm_A mol:protein length:190 hypothetical protein TT2028  ali model follow..  11  1.MG-MLGLDLLKEVPGLLEE-IKALPL-------RLDEERFRFWLQQDYPFVEALYRYQVGLLLEAPQAHRAPLVQALMATVEEL---DWLLLQGASPSAP--------VHPVRAGYIALLEE-MGRLPYAYRVVFFYFLNGLFLEAWAHHVP-------EGPWAELSQHWFAPEQAVLYDLEVLARGLW-EDLDPEVVRTYLRRILEAEKATWSLLL..................... 190
28 -27.7001xk0_A mol:protein length:233 Heme oxygenase 1  ali model follow..  15  9.MPQDLSEALKEATKEV-HTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKES--------PVFAPVYFPEELHRKAALEQDLAFWYGPRWQ-EVIPYTPAMQRYVKRLHEVGRT-EPELLVAHAYTRYLADLSGGQVLKKAQKALDLPSSGAFFTFPNIASATKFKQLYESRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRA...... 233
29 -27.4001we1_A mol:protein length:240 Heme oxygenase 1  ali model follow..  12  1.MSVNLASQLREGTKKS-HSMAENVGFVKCFLKGVVEKNSYRKLVGNLYFVYSAMEEEMAKFKDH---------PILSHIYFPELNRKQSLEQDLQFYYGSNWR-QEVKISAAGQAYVDRV-RQVAATAPELLVAHSYTRYLGDLSGGQILKKAQNAMNLHDGGAFYEFADIDDEKAFKNTYRQAMNDLPIDQATAERIVDEANDAFAMNMKMFNELEGNLIKAIGIMVFNSLTRRRSQ 228
30 -27.3005uc8_A mol:protein length:226 Heme oxygenase 2  ali model follow..  11  1.MGSSLSELLKEGTKEA-HDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDH--------PAFAPLYFPMELHRKEALTKDMEYFFGENWE-EQVQCPKAAQKYVERIHYIGQN-EPELLVAHAYTRYMGDLSGGQVLKKAQRALKLPSTTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAGS................. 220
31 -27.2005kzl_A mol:protein length:212 Heme oxygenase  ali model follow..  14  1GGSMSLATILREGTSEE-HKAAESSAFIRSFMKGILEKGTYARHLEAFYYVYESMEEELERNKNN---------LVLKSIYFPELYRKNALLEDLQFFYGTWKP-NDHQPSVATQDYVQRI-RKISETQPELLAAHSYVRYLGDLSGGQILKKAARALNLPEGK--YEFPMIQDINGFKQNYRTALDSLPVNDSEKQSILAESKQVFLLNQGIFSEL...................... 212
32 -25.4001dve_A mol:protein length:267 HEME OXYGENASE-1  ali model follow..  12  9.MSQDLSEALKEATKEV-HIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQN--------PVYAPLYFPEELHRRAALEQDMAFWYGPHWQ-EAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTEEHKDQSPSQTEFLRQR 239
33 -25.3002q32_A mol:protein length:264 Heme oxygenase 2  ali model follow..  10  30..MADLSELLKEGTKEA-HDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDH--------PAFAPLYFPMELHRKEALTKDMEYFFGENWEE-QVQAPKAAQKYVERIHYIGQN-EPELLVAHAYTRYMGDLSGGQVLKKAQRALKLPSTTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAGSTLARETLEDGFPVHDG. 258
34 -23.8001dvg_A mol:protein length:267 HEME OXYGENASE-1  ali model follow..  14  9.MSQDLSEALKEATKEV-HIRAENSEFMRNFQKGQVSREGFKLVTASLYHIYTALEEEIERNKQN--------PVYAPLYFPEELHRRAALEQDLAFWYGPHWQ-EAIPYTPATQHYVKRLHEVGGT-HPELLVAHAYTRYLGDLSGGQVLKKAQKALALPSSGASFTFPSIDNPTKFKQLYRARMNTLELTPEVKHRVTEEAKTAFLLNIELFEELQALLTEEHKDQSPSQTEFLRQR 239
35 -22.9001wov_A mol:protein length:250 Heme oxygenase 2  ali model follow..  12  1.MT-NLAQKLRYGTQQS-HTLAENTAYMKCFLKGIVEREPFRQLLANLYYLYSALEAALRQHRDN---------EIISAIYFPELNRTDKLAEDLTYYYGPNWQ-QIIQPTPCAKIYVDRL-KTIAASEPELLIAHCYTRYLGDLSGGQSLKNIRSALQLPGEGTAMYEFDSLPTPGD-EIYRDVLNSLPLDEATINRIVEEANYAFSLNREVMHDLEDLIKAAIGEHTFDLLTRQDRP 231
36 -22.6004wd4_A mol:protein length:292 Heme oxygenase 1  ali model follow..  15  13.MPQDLSEALKEATKEV-RTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKES--------PVFAPVYFPEELHRKAALEQDLAFWYGPRWQ-EVIPYTPAMQRYVKRLHEVGRT-EPELLVAHAYTRYLGDLSGGQVLKKAQKALDLPSSGAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQR 243
37 -22.1001j77_A mol:protein length:209 HemO  ali model follow..  11  1.MSETENQTFAKRLKADTTAVHDSVDNLVMSVQPFVSKENYIKFLKLQSVFHKAVDHIYKDAELNKAIPE------------EYMARYDAVTQDLKDLGEEPYKFDKELPYE----------------AGNKAIGWLYCAEGSNLGAAFLFKHAQKLDYNGEHGARHLAPHPDGRGKHWRAFVEHLNALNLTPEAEAEAIQGAREAFAFYKVVLRETFGLAADAEAPEGMM........ 205
38 -20.4004raj_A mol:protein length:247 Heme oxygenase  ali model follow..  10  17..AEPLTKRLSKASRKIHNV--SNSLVNARLIALFSDKDLYAKALGCFYYVFVALEAALDEALKKGDADVSKFKDVLK----GGLYRAPGFKQDVQHYLGATWQAQLGTKSQALKDYEAHLASLGRSSPALLLAHVYTQHLAMASGGQIVKRWARKIFQLDDVGTAAFDYTGESNNTLRSAFKKQFDEWGAPQELQDQLLSEHLAAFGHNNAIIKAFPLPATAIIAGAIRVTP...... 244
39 -19.5001sk7_A mol:protein length:198 hypothetical protein pa-HO  ali model follow..  9  1.MDTLAPESRSQRLNLLTNEPHQRLESLVKSKEPFASRDNFARFVAAQYLFQHDLEPLYRNEALARLFPG------------ASRARDDAARADLADLGHPVPEGDQSVREADL--------------SLAEALGWLFVSEGSKLGAAFLFKKAAALELDENFGARHLAEPEGGRAQGWKSFVAILDGIELNEEEERLAAKGASDAFNRFGDLLERTF..................... 197
40 -17.2005hyg_A mol:protein length:317 Uncharacterized protein  ali model follow..  12  46.....................FRGHPIWERLSDERLLSWGWVAYNRNTVLIEQRIANPAFELVIG--LGGQQLELAVAQAMVDEQYHTLMHINGSAVTRSDFSDRVLPDSHITTIHQEHLDRCEEPWQRSLTTLGFATVAEIS---INAYLDLLADDQEIQVVNSTTVKLHNRDEYCHASISGEMMKQVALPADRRRFLLEKVVAGLEAFVATWESIVAFEGVPGWEKAAAEVREAQGG 276
41 -17.0005uxi_A mol:protein length:234 Aldehyde decarbonylase  ali model follow..  8  2........................QQLTDQSKELDFKSETYKDAYSRINAIVIEGEQEAHENYITLAQLLPESHDELIRLSKMESRHKKGFEACGRNLAVTPDLQFAKEFFSGLHQNFQTAAA--EGKVVTCLLIQSLIIECFAIAAYNIYIPV-----ADDFARKITEGVVKEEYSHLNFGEVWLKEHF--AESKAELELANRQNLPIVWKMLNQVEGDAH................. 190
42 -16.9004quw_A mol:protein length:231 Aldehyde decarbonylase  ali model follow..  9  2.........................PQLEASLELDFQSESYKDAYSRINAIVIEGEQEAFDNYNRLAEMLPDQRDELHKLAKMEQRHMKGFMACGKNLSVTPDMGFAQKFFERLHENFKAAAA--EGKVVTCLLIQSLIIECFAIAAYNIYIPVA-----DAFARKITEGVVRDEYLHRNFGEEWLKANF--DASKAELEEANRQNLPLVWLMLNEVADDARE................ 190
43 -16.0004z5s_A mol:protein length:231 Aldehyde decarbonylase  ali model follow..  9  15......................................EIYKDAYSRINAIVIEGEQEAYSNYLQMAELLPEDKEELTRLAKMENRHKKGFQACGNNLQVNPDMPYAQEFFAGLHGNFQHAFS--EGKVVTCLLIQALIIEAFAIAAYNIYIPVA-----DDFARKITEGVVKDEYTHLNYGEEWLKANF--ATAKEELEQANKENLPLVWKMLNQVQGDAK................. 189
44 -15.8004kvr_A mol:protein length:244 Aldehyde decarbonylase  ali model follow..  12  1GMP------TLEMPVAAVLDSTVGSSEALPDFTSDRYKDAYSRINAIYIEGEQEAHDNYIAIGTLLPD----HVEELKRLAKMEMRHKKGFTACGKNLGVEADMDFAREFFAPLRDNFQTALG--QGKTPTCLLIQALLIEAFAISAYHTYIPV-----SDPFARKITEGVVKDEYTHLNYGEAWLKANL--ESCREELLEANRENLPLIRRMLDQVAGDAA................. 203
45 -15.8005ux2_A mol:protein length:234 Aldehyde decarbonylase  ali model follow..  10  1..............................MTQLDFASAAYREAYSRINGVVIVGEGLANRHFQMLARRIPADRDELQRLGRMEGDHASAFVGCGRNLGVVADLPLARRLFQPLHDLFKRHDH--DGNRAECLVIQGLIVECFAVAAYRHYLPVAD-----AYARPITAAVMNDESEHLDYAETWLQRHF--DQVKARVSAVVVEALPLTLAMLQSLAADMR................. 183
46 -15.7004pgi_A mol:protein length:250 Aldehyde decarbonylase  ali model follow..  11  29......................................DRYKDAYSRINAIVIEGEQEAHDNYIAIGTLLPDHVEELKRLAKMEMRHKKGFTACGKNLGVKADMDFAREFFAPLRDNFQTALG--QGKTPTCLLIQALLIEAFAISAYHTYIPVS-----DPFARKITEGVVKDEYTHLNYGEAWLKANL--ESCREELLEANRENLPLIRRMADQVAGDAA................. 203
47 -15.6005uwz_A mol:protein length:243 Aldehyde decarbonylase  ali model follow..  9  12..................................DYRSDTYRDAYSRINAIVLEGEREAHANYLTLAEMLPDHAEALKKLAAMENRHFKGFQSCARNLEVTPDDPFARAYFEQLDGNFQQAAA--EGDLTTCMVIQALIIECFAIAAYNVYIPVA-----DAFARKVTEGVVKDEYTHLNFGQQWLKERF--VTVREGIERANAQNLPIVWRMLNAVEADTE................. 190
48 -15.6005k52_A mol:protein length:265 Aldehyde decarbonylase  ali model follow..  12  41......................................ETYKDAYSRINAIVIEGEDEAANNYVRLAELMPEQSEELASLAKMEARHKKGFTACGKNLNVTPDMDFAKKFFSDLHGNFQVAAA--AGNIVTCLLIQALIIEAFAISAYNVYIPH-----ADDFARKITENVVKDEYLHLNFGEQWLKANF--ESAKDELERANRENLAIVWRMLDEVAGDAL................. 215
49 -15.6005k53_A mol:protein length:262 aldehyde deformylating oxygenase  ali model follow..  9  41......................................ETYKDAYSRINAIVIEGEQEAHDNYLTLAELLADKKAELVGLSKMENRHMKGFQACGRNLKVTPDMAFAKQFFSELHKNFQTAAA--QGQIVTCLLIQSLIIECFAIAAYNIYIPVA-----DDFARKITEGVVKEEYSHLNFGEVWLQAHF--EESKAELEAANRQNLPIIWKLLNAVADDAR................. 215
50 -15.5002jcd_A mol:protein length:345 N-OXIDASE  ali model follow..  12  77.....................FAEHPLFLAAEPHQVLTGMWIGYNERVIATEQLIAEPAFDLVMH--SDDPLIRKSVQQAIVDESFHTYMHMLAIDRTRRKISERPPQPELVTYRRLRRVLADMPEQWE-IAVLVWGAVAETC---INALLALLARDATIQPMHSLITTLHLRDETAHGSIVVEVVREL-MNEQQRRALVRCLPIALEAFAE........................... 275
51 -14.6005uxg_A mol:protein length:220 aldehyde deformylating oxygenase  ali model follow..  7  5...........................WFSTPQEI--REGIKYLSAHFYPASIMDRWKILKKLSFEKAKIIAN--YSLQQVIEEIEHFDFFNEYFKEDPLTTVRLP-----PSYIKLFDGLVEDFQSSR-NIATRFHMITEGVLATVGLKILNETSRKYNLLKFNEGIKRIIEDEARHVSFGLSLIEDKEYAVKRVEELFPLAVQIVKEGKDKIEPL...................... 187
52 -14.2003pvr_A mol:protein length:311 Phenylacetic acid degradation protein paaA  ali model follow..  11  1.MRSTQEERFEQRIAQ------------TAIEPQDWMPDAYRKTLIRQIGQHAHGMLPEGNWITRAPTLRRKA--ILLAKVQDEAGHGLYLYSAAETLGCAREDIYQKMLDGRMKYSSIFNYPT---LSWADIGVIGWLVDGAAIVNQVALCRTS------GPYARAMVKICKEESFHQRQGFEACMALAQSEAQKQMLQDAINRFWWPALMMFG........................ 198
53 -13.7004iit_A mol:protein length:320 Phenylacetate-CoA oxygenase subunit PaaA  ali model follow..  11  2GSS-------GSTEEQRFDQRIAQETAIEPQDWPDAYRKTLIRQIGQHAHSEIVGMLPEGNWITRAPTLRRKA--ILLAKVQDEAGHGLYLYSAAETLGCAREDLYQKMLDGQMKYSSIF----YPTLSWADIGVIGWLVDGAAIVNQVALCRTS------GPYARAMVKICKEESFHQRQGFEACMALAQNEAQRQMLQDAINRFWWPALMMFG........................ 201
54 -13.6004mud_A mol:protein length:235 Ring oxydation complex/ phenylacetic acid degradation related protein  ali model follow..  9  1GMKLRSVKEVPQDLTNTLVN------IIELRADFELA-----------------MVEQYSPWLVNAPTVDSRL--FVAKLVSDELNHGWQLVRLLEEFKVKDVIERISNARLGIHKLEVSNL---PLFNWEDVIAFTFLVDGAGLYQLKILKDCSF-----EPLSTLASSMIKEEESHIFFSQNELRNYQNKNRMQGAINFWFPRAVEML............................. 178
55 -13.4004hr0_A mol:protein length:316 Ribonuleotide reductase small subunit  ali model follow..  9  55...........................FASLTSEE--KISALPLVAGFSAGEEAVTLDILPMAHALARQGREDVLFLTTFMHDEAKHVEMFSRWQQAVGIGQMDLSVFHNDHYKRIFYEALPEAMNR---RAATVYNMIVEGTLAESGYTFRQIYKKAGLFPGLLQGIDYLNMDEGRHIQFGIYTIQRIVNEERYYELFIRYMDELWPHVIGYVDYLTE.................... 255
56 -13.1001za0_A mol:protein length:275 POSSIBLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA2 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE)  ali model follow..  10  1.MAQKPVAALTLELEPVVEANMTRH----DPSQSTLPRTITD--ACEILLILKDNLAGHHRELVEHFILEDWWGRWLGRWTAEEHLHAIALREYLVVTREVDPVANEDVRVQHVMK-------RAEKYTQVETLVYMAFYERCGAVFCRNLAAQIE-----EPILAGLIDRIARDERHEEFFANLVTHCLDYTRDET.......................................... 211
57 -12.9001mhy_D mol:protein length:521 METHANE MONOOXYGENASE HYDROXYLASE  ali model follow..  7  67.......AAKDERQFGTLLDGLTRLGAGNKVHPR---GETMKVISNFLEVGEYNAIAASAMLWDSATAAE--QKNGYLAQVLDEIRHTHQCAFINHYYSKHYHDPAGHNDAPLWKGMKRVFADGFISGDAVESVNLQLVGEACFTNPLIVAVTEWASANGDEITPTVFLSVETDELRHMANGYQTVVSIANDPASAKFLNTDLNNAFWTQQKYFTPV...................... 280
58 -12.9003rm5_A mol:protein length:550 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20  ali model follow..  14  347...................DSYINHEFVKKVADGTLERKKFQFFIEQDYAYLVDYARVHCIAGSKAPCEDMEKELVIVGGVRTEMGHEKRLKEVFGVK--DPDYFQKIKRGPALRAYSRYFNDVSRRGNWQELVASLTPCLMGYGEALTKMKGKVTAPE-GSVYHEWCETYASSWREAMDEGEKLLNHILEPPEQLDTLVTIYAEVCELETNFWTAALEY................... 549
59 -12.6001vjx_A mol:protein length:157 putative ferritin-like diiron-carboxylate protein TM1526  ali model follow..  12  1.MGSDKIMKVSDILTVAIRLEEEGERFYRELSE----------------------------------HFNGEIKKTFLELADQERIHAEIFRKMSDQENWDEVDSYLAGYAFYEVFPDTSEILRRKDLTLKEVLDIAISVEKDSIILYYELKDGLV----NSDAQKTVKKIIDQEKEHLRKLLEMKREST................................................. 151
60 -12.6003sid_A mol:protein length:180 Symerythrin  ali model follow..  11  1.MGLNYNQEDFMGLDRFFQDAVSHNNTDANAASS-IEVEMYE--CDCMYPTFAEIAR---------RSGQPEIGAMFDAIAKEEGMHAQLLTKLYSELEVKDSAETLEAKRLVSTIESQIDAVASDSRGLRRALETALEVETIEQKTYPAFAKLAAEQG-NMEVATAFEAIVKSETKHANWVKRALENLLEVA.............................................. 180
61 -12.6003dhg_B mol:protein length:327 toluene 4-monooxygenase hydroxylase beta subunit  ali model follow..  8  78.LVYRTYNLMQDGQESYVQSLFNEREHDQMVREG---EHTMARCYSPLRYLFHCLQMSSAYVQQMAPAST--ISNCCILQTADSLRWLTHTAYRTHELSLTYPDAGLGEHEPGWQGLRELMEKQLTAFDWGEFVSLNLVVKPMIVES-KPLQQQAWENN--DTLLPLLIDSQLKDAEHSRWSKALVKHALENPDNHAVIEGWIEKWRPLADRAAEAYLSMLSSDILPAQYLERSTSLRA 322
62 -12.1002rcc_A mol:protein length:346 Ribonucleoside-diphosphate reductase subunit beta  ali model follow..  8  1GMEQLQKRKIYDTTASNASTGILRFSWAYPLYK-SHDAKQFPTLTETEQEAFKKIIGLLAFLDSVQTDTDSSLAALMSVLSFQEVVHNQSYSYVLSSLVPKATQFEYWKHDDVLKERNEFIIDGYEKKTFLESIVYDVILEGLNFYSGFAFFYNLARNQKMVSTSTMINYINRDEQLHVYLFTNIFKELLVEFPEKTFVKTTLMKAADLEKDWFRYIIGD................... 271
63 -11.9003ee4_A mol:protein length:323 Probable ribonucleoside-diphosphate reductase  ali model follow..  9  49...........................WEKLSDDE--RDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRADEMYLTQFAFEEAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNA--RASVTYNHIVEGMLALTG-AWHKICVERAILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDAETRMNELIPLALRLIEEGFALYGD.................... 254
64 -11.9003n37_A mol:protein length:319 Ribonucleoside-diphosphate reductase 2 subunit beta  ali model follow..  10  41....................................DIPAWQTLTVVEQQLTMRVFTGLTLLDTLQNVLTPHEEAVLSNISFMEAVHARSYSSIFSTLCQTKDVYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNMEKEELKSFAFDLLLELYDNELQYTDELYAE................... 243
65 -11.8001uzr_A mol:protein length:296 RIBONUCLEOTIDE REDUCTASE R2-2 SMALL SUBUNIT  ali model follow..  10  46....................................DIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTLTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIFRWSEENRNLQRKAEIVLQSYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQRGLALVDDKDYTYELLFELYDNEVEYTQDLYDE................... 248
66 -11.7001kgn_A mol:protein length:329 Ribonucleotide reductase protein R2F  ali model follow..  8  51....................................DIQSWNKMTPQEQLATMRVFTGLTLLDTIQGTETMHEEAVYTNIAFMESVHAKSYSNIFMTLASTPQIFRWSEENENLQRKAKIIMSYYNGDDPLKKKVASTLLESFLFYSGFYLPMYLSSRAKLTNTADIIRLIIRDESVHGYYIGYKYQQGVKKLSEKAYTFDLMYDLYENEIEYTEDIYDD................... 253
67 -11.6003ogh_B mol:protein length:171 Protein yciE  ali model follow..  10  7.....................................IEHYHDWLRDAHAMEKQAESMLESMASRIDN-YPELRARIEQHLSETKNQIVQLETILDRNDISRSVIKDS--MSKMAALGQSIGGIFPSDEIVKGSISGYVFEQFEIACYTSLLAAAKNAG-DTASIPTIEAILNEEKHMADWLIQHIPQTTEKFLIRSET........................................ 164
68 -11.5002fzf_A mol:protein length:175 hypothetical protein  ali model follow..  7  6.........................EVREGLPIEKMADFSLEELLGMAIKAEIGAREFYKSLAEKIK--IEALKEKINWLAEEEKKHEALLRKLYSQM--FPGKEVVFPKEHIGPELQPVARELEKVQDIIDLIRWAMKAEEIAAEFYLKLEEMVK----EEEKKRLMRYLADMERGHYYTLRAEYELLLNWEM............................................. 166
69 -11.5004n83_A mol:protein length:319 Ribonucleoside-diphosphate reductase subunit beta  ali model follow..  6  40....................................DLDDWRKLSHKEKDLVGKVFGGLTLLDTLQSERTAHEEAVFNNIQFMESVHAKSYSSIFSTLNTKSEIFAWTNTNPYLQKKAEIINEIYLNGTALEKKIASVFLETFLFYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLAFNEEKLKEWMYDLLYTLYENEEGYTESLYDT................... 242
70 -11.5001t0q_B mol:protein length:330 toluene, o-xylene monooxygenase oxygenase subunit  ali model follow..  5  102...................DQLNDRGHDQMLTRE---VETLARFYTPARYLFHALQMGSVYIHQIAP--ASTITNCATYETADHLRWLTHTAYRTRELANCYPDVGFGKREPAWQGFRELIEKALIAWDWGEFTAINLVTKPAVEEALLQQLGSLAQSEGDTLLGLLAQAQKRDAERHRRWSSALVKMALEKEGNREVLQKWVAKWEPLADKAIEAYCSALPDGENAIVEAKSASRY.. 323
71 -11.3002uw2_A mol:protein length:332 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT  ali model follow..  10  55....................................DIQHWESLKPEERYFISHVLAFFAASDGIVNEQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGPMPGLTFSNELISRDEGLHCDFACLMFKHL-VHKPSEERVREIIINAVRIEQEFLTEALP.................... 252
72 -11.3006gp2_A mol:protein length:345 Ribonucleoside-diphosphate reductase beta chain  ali model follow..  9  67....................................DLTSWRTLTPEWQELITRTFTGLTLLDTIQATLTDHEQVIYTNFAFMVAVHARSFGSIFSTLCSSEQIHEWVINTETLQERAKALIPYYVNDDPLKSKVAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHNYYSGYKYQKKVAKAEMKEFVFKLLYELIDLEKAYLKELYED................... 269
73 -11.3004iit_C mol:protein length:251 Phenylacetate-CoA oxygenase subunit PaaC  ali model follow..  11  4.....................................PNPVATYALRLGDNGLVLAQRLGAWCGHAPELEIDLA--LANIGLDLLGQARNFLSYAAELNGCGDE-DTLAFGRDERQYSNLLLVEQPNGNFADTIARQFFIDVWHVALYSRLVNSR------AQLAAIAAKGLKEVRYHLRFSRGWLERLGNTELSNRKMQQAVDNLWRFTGELFLADEVELSLVEQGIAVDPRELQAE. 197
74 -11.3002oh3_A mol:protein length:167 COG1633: Uncharacterized conserved protein  ali model follow..  12  1GM----GYTLAEFLAHAIALETEAAERYVELAD------------------------------MMEAHNNLDTATVFRDMARFSTLHGDEIKQRSRALELPKLMSWQYRWKTPPEVGDE---DIHYLMTPYHALRYARDNEIRGMEYYKEAAANSA----DPEVKRLGADFAAEEAEHVVALDKWIEKTPRPSI............................................. 154
75 -11.3006ebo_A mol:protein length:355 Ribonucleoside-diphosphate reductase, beta subunit  ali model follow..  8  71....................................DLPSWNELDDDWQQLITRTFTGLTLLDTVQSSLTEQEQVIYANFAFMVGVHARSYGTIFSTLCTSEQIHEWVVDNEALQARPKALIPFYTADDPLKSKIAAALMPGFLLYGGFYLPFYLSARGKLPNTSDIIRLILRDKVIHNFYSGYKYQLKVAKLSPKQFVFDLLDKMIGLEKTYLHQLYD.................... 272
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Damiano JS, Stehlik C, Pio F, Godzik A., Reed JC. CLAN, a novel human CED-4-like gene. Genomics. 2001 Jul;75(1-3):77-83.