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Query: 3kt1_A mol:protein length:633 PKHD-type hydroxylase TPA1, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLEEDKIKGMFNPKIWDKTFQDGLKKEIEDSQPYNWGTIHELVNDDLLRAVRKEIETEIHFTKKETDIYRVNQSGDLANLSGLDWDDLSRLPNLFKLRQILYSKQYRDFFGYVTKAGKLSGSKTDMSINTYTKGCHLLTHDDVIGSRRISFILYLPDPDRKWKSHYGGGLRLFPSILPNVPHSDPSAKLVPQFNQIAFFKVLPGFSFHDVEEVKVDKHRLSIQGWYHIPQVGEEGYIPGEEEAWVRNNTSTLAQIESNVLEDFEFPKDERNILSFHEVKHFEKMLKGDAGAKTDNTPKESMTSVISDSVKLSEAEFTYLSQYISPEHLSSKGIEKLQKQFVENSSLQIESFLNDDKSELLKKVIKQKELEQECPYHSKDVKAPWKTAIPPHKARYLYIDGKEYRNFQTEADILEALNNNDLPNFQFTKDAIKIISDASGNSRENNFDAELALIDLAVFHKSTIFKKYLALLTSLCPVSEQILIRRFRPGMDFTLATKCRFNELLKSNPDIIDAVLEGTLCLTPSAGWESGELGGYELYMMDDDEDNKQYLKEDVEDASVYRADDSGDSVLINDPPAWNTFNLVLRDESVLEFVKYVSWSAKSSRWDVKMKWDVKSCDEDGQEDEALELast
1 -176.0003kt1_A mol:protein length:633 PKHD-type hydroxylase TPA1  ali model  100  1MLEEDKIKGMFNPKIWDKTFQDGLKKEIEDSQPYNWGTIHELVNDDLLRAVRKEIETEIHFTKKETDIYRVNQSGDLANLSGLDWDDLSRLPNLFKLRQILYSKQYRDFFGYVTKAGKLSGSKTDMSINTYTKGCHLLTHDDVIGSRRISFILYLPDPDRKWKSHYGGGLRLFPSILPNVPHSDPSAKLVPQFNQIAFFKVLPGFSFHDVEEVKVDKHRLSIQGWYHIPQVGEEGYIPGEEEAWVRNNTSTLAQIESNVLEDFEFPKDERNILSFHEVKHFEKMLKGDAGAKTDNTPKESMTSVISDSVKLSEAEFTYLSQYISPEHLSSKGIEKLQKQFVENSSLQIESFLNDDKSELLKKVIKQKELEQECPYHSKDVKAPWKTAIPPHKARYLYIDGKEYRNFQTEADILEALNNNDLPNFQFTKDAIKIISDASGNSRENNFDAELALIDLAVFHKSTIFKKYLALLTSLCPVSEQILIRRFRPGMDFTLATKCRFNELLKSNPDIIDAVLEGTLCLTPSAGWESGELGGYELYMMDDDEDNKQYLKEDVEDASVYRADDSGDSVLINDPPAWNTFNLVLRDESVLEFVKYVSWSAKSSRWDVKMKWDVKSCDEDGQEDEALE 627
2 -172.0003mgu_A mol:protein length:644 PKHD-type hydroxylase TPA1  ali model follow..  100  21.LEEDKIKGMFNPKIWDKTFQDGLKKEIEDSQPYNWGTIHELVNDDLLRAVRKEIETEIHFTKKETDIYRVNQSGDLANLSGLDWDDLSRLPNLFKLRQILYSKQYRDFFGYVTKAGKLSGSKTDMSINTYTKGCHLLTHDDVIGSRRISFILYLPDPDRKWKSHYGGGLRLFPSILPNVPHSDPSAKLVPQFNQIAFFKVLPGFSFHDVEEVKVDKHRLSIQGWYHIPQVGEEGYIPGEEEAWVRNNTSTLAQIESNVLEDFEFPKDERNILSFHEVKHFEKMLKGDAGAKTDNTPKESMTSVISDSVKLSEAEFTYLSQYISPEHLSSKGIEKLQKQFVENSSLQIESFLNDDKSELLKKVIKQKELEQECPYHSKDVKAPWKTAIPPHKARYLYIDGKEYRNFQTEADILEALNNNDLPNFQFTKDAIKIISDASGNSRENNFDAELALIDLAVFHKSTIFKKYLALLTSLCPVSEQILIRRFRPGMDFTLATKCRFNELLKSNPDIIDAVLEGTLCLTPSAGWESGELGGYELYMMDDDEDNKQYLKEDVEDASVYRADDSGDSVLINDPPAWNTFNLVLRDESVLEFVKYVSWSAKSSRWDVKMKWDVKSCDEDGQEDEA.. 644
3 -171.0004nhk_A mol:protein length:647 PKHD-type hydroxylase TPA1  ali model follow..  100  18.LEEDKIKGMFNPKIWDKTFQDGLKKEIEDSQPYNWGTIHELVNDDLLRAVRKEIETEIHFTKKETDIYRVNQSGDLANLSGLDWDDLSRLPNLFKLRQILYSKQYRDFFGYVTKAGKLSGSKTDMSINTYTKGCHLLTHDDVIGSRRISFILYLPDPDRKWKSHYGGGLRLFPSILPNVPHSDPSAKLVPQFNQIAFFKVLPGFSFHDVEEVKVDKHRLSIQGWYHIPQVGEEGYIPGEEEAWVRNNTSTLAQIESNVLEDFEFPKDERNILSFHEVKHFEKMLKGDAGAKTDNTPKESMTSVISDSVKLSEAEFTYLSQYISPEHLSSKGIEKLQKQFVENSSLQIESFLNDDKSELLKKVIKQKELEQECPYHSKDVKAPWKTAIPPHKARYLYIDGKEYRNFQTEADILEALNNNDLPNFQFTKDAIKIISDASGNSRENNFDAELALIDLAVFHKSTIFKKYLALLTSLCPVSEQILIRRFRPGMDFTLATKCRFNELLKSNPDIIDAVLEGTLCLTPSAGWESGELGGYELYMMDDDEDNKQYLKEDVEDASVYRADDSGDSVLINDPPAWNTFNLVLRDESVLEFVKYVSWSAKSSRWDVKMKWDVKSCDEDGQEDEA.. 641
4 -104.0004nhx_A mol:protein length:562 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1  ali model follow..  18  32..GKKEVMAEFSDAVTEETLKKQVAEAWSRRDPFLHCVIPNFIQSQDFLEGLQKELMNLDFHEKYNDLYKFQQSDDLKKRREPHI----------STLRKILFEDFRSWLSDISKIDLE--STIDMSCAKYEFTDALLCHDDELEGRR---IAFILYLVPPWDRSMGGTLDLYSIDEHF-QPKQIVKSLIPSWNKLVFFEV-SPVSFHQVSEVSEEKSRLSISGWFHGPSLTRPPNYFEPPIPRSPH----------------------------------------------------------------IPQDHEILYDWINPTYLDMDYQVQIQEEFEESSEILLKEFLKPEKFTKVCEALEHGHVE-------------WSSRGPPNKRFYEKAEESKLPEILKECMKLFRSEALFLLLSNFTGLKLHFLATSHSPPEPENNQMAISNNSQQSNEQTDPEPEENETKKESSVPMCQGELRHWKTGHYTLIHDHSKAEF-----------ALDLILYCGCEG--WEPEYGGFTSYIA-----------------------KGEDEELLTVNPESNSLALVYRDRETLKFVKHINHRSLEQFWDFSFIYYE.............. 556
5 -56.0005v1b_A mol:protein length:240 Egl nine homolog 2  ali model follow..  13  8............PSAPERLALDYIVPCM---RYYGICVVDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHAVIRHCAGRLGSYKINGRTKAMVACYPGNGLGYVRHVDNPHGDG-RCITCIYYLNQNWDVKVHGGLLQIFPEGR-----PVVANIEPLFDRLLIFW-SDRRNPHEV--KPAYATRYAITVWYFDADERARAKDKYQLASGQKGVQVPVSQ..................................................................................................................................................................................................................................................................................................................................................................................... 239
6 -53.9004kbz_A mol:protein length:238 Egl nine homolog 1  ali model follow..  11  1.......GSQTKPLPALKLALEYIVPCM---NKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDG-RCVTCIYYLNKDWDAKVSGGILRIFPEGK-----AQFADIEPKFDRLLFFW-SDRRNPHEV--QPAYATRYAITVWYFDADERARAKVKYLTGEKGLRVELNKPS..................................................................................................................................................................................................................................................................................................................................................................................... 237
7 -53.8002g19_A mol:protein length:244 Egl nine homolog 1  ali model follow..  12  13.................KLALEYIVPCM---NKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDG-RCVTCIYYLNKDWDAKVSGGILRIFPEGK-----AQFADIEPKFDRLLFFW-SDRRNPHEV--QPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELN........................................................................................................................................................................................................................................................................................................................................................................................ 236
8 -53.0004iw3_A mol:protein length:229 Putative uncharacterized protein  ali model follow..  15  22................EHPMLAAVVDDL---ATHGWSQQAHFLPADLVRALAAECRRRDAEGELNPAGVGRGATQEVRETIRGDQIQWIDPGQAEACDQYL--AAMDQLRLAINQGLFLGLEDFECHFALYPPGAFYRRHLDRFRDDDRRMVSAVLYLNEGWQPHDGGQLRMFLADGV-------EHDVEPVAGCLVVFL--SGEVPHEVLPA--GRERLSLTGWFRRRGND........................................................................................................................................................................................................................................................................................................................................................................................................... 221
9 -52.9002hbt_A mol:protein length:247 Egl nine homolog 1  ali model follow..  11  5...............ALKLALEYIVPCMNK---HGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDG-RCVTCIYYLNKDWDAKVSGGILRIFPEGK-----AQFADIEPKFDRLLFFW-SDRRNPHEV--QPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPS..................................................................................................................................................................................................................................................................................................................................................................................... 233
10 -51.5005l9v_A mol:protein length:252 Egl nine homolog 1  ali model follow..  11  17................LKLALEYIVPAM---NKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSDDLICHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNCNGDG-RCVTCIYYLNKDWDAKVSGGILRIFPEGK-----AQFADIEPKFDRLLFFW-SDRRNPHEV--QPAYATRYAITVWYFDADERAAAKVKYLTGEKGVRVELNKPS..................................................................................................................................................................................................................................................................................................................................................................................... 244
11 -51.4002y33_A mol:protein length:252 EGL NINE HOMOLOG 1  ali model follow..  11  3..HMASPNGQTKPLPALKLALEYIVPCM---NKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDG-RCVTCIYYLNKDWDAKVSGGILRIFPEGK-----AQFADIEPKFDRLLFFW-SDRRNPHEV--QPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPS..................................................................................................................................................................................................................................................................................................................................................................................... 244
12 -50.5005lbc_A mol:protein length:252 Egl nine homolog 1  ali model follow..  11  17................LKLALEYIVPCM---NKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSDDLVLHCNGKLGSYKVNGRTKAMVACYPGNGTGYVRHVDNPNGDG-RCVTCIYYLNKDWDAKVSGGILRIFPEGK-----AQFADIEPKFDRLLFFW-SDRRNPHEV--QPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPS..................................................................................................................................................................................................................................................................................................................................................................................... 244
13 -49.8006ey1_A mol:protein length:257 HIF prolyl hydroxylase  ali model follow..  12  22.IGCDKTGLALEKTWQLQKNERLSNMVVNQLNTNGFCIINNFLGSSCSTEVLQQVLNLYQSGVFSNG--QLARNVSVNRIRGDKIAWIGGDERGCEAIKYLSSDSLISRCNGRLGNYMITGRTKCMVACYPGSGLGYIRHIDNPNRDG-RCVTVLYYLNPNWNSQDCGGQLWLYPNNE-----NKVVKIDPIFDRLLLFW-SDRRNPHEV--KPAYAMRYAITLWYFDEKERALSSQNG.................................................................................................................................................................................................................................................................................................................................................................................................... 250
14 -29.0005iqs_A mol:protein length:315 WelO5  ali model follow..  14  41.................KKYPTAIQDIIINRS-FDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGHAIVGQSPDLKDYFASSAIFRQACRTMFQEQVESIFHSLSGLPVEIPTGTPATIRLLLEGREIAVHVGNDFLDLSDQLSYFIPLT---VPEAGGELVVYSLEWNPQEASKQSVAYAPGPGDMLLFN--GGRYYHRVSEVIGNSPRRTIGGFLAFSKQRD.......................................................................................................................................................................................................................................................................................................................................................................................................... 302
15 -25.2003dkq_A mol:protein length:243 PKHD-type hydroxylase Sbal_3634  ali model follow..  12  1...............MGSDKIENLYFQ-------MLIEIPNVFSKQEVSHLREQLDAR---RWIDGNQTSGAMATTRKRNQQLDKDDPVAVALGQQIMDRLLAHPQFVSAALPLQFYPP-------LFNRYQGGETFGYHIDNAMIRTDLSATLFLSEPENYQ---GGELVIQDTYGQ--------QSIKLSAGSLVLY---PSSSLHQVTPVLSGE-RTAAFMWLQSM.............................................................................................................................................................................................................................................................................................................................................................................................................. 190
16 -24.1003w20_A mol:protein length:273 Putative uncharacterized protein  ali model follow..  10  11.....RFGTAARAEHMTIAAAIHALD-----ADEADAIVMDIVPDGERDAWWDDEGFSSSPFTKNAHHAGIVATS--EQGDKLVSKAAEYFGIACRVNDGLRTTRFVRLFSDALDAKPLTIGHDYATRRVYEPFE-FAPHCDDVSYGR-RQLGGFLTIQ---GADNDAGMVMWDNRPESRAALDEKIMLKPQPGQLTLF---QSKNLHAIERC--TSTRRTMGLFL................................................................................................................................................................................................................................................................................................................................................................................................................. 262
17 -22.8006ax6_A mol:protein length:235 Procollagen lysyl hydroxylase and glycosyltransferase  ali model follow..  11  20LYDLPTRKEEWEKKYLHPEFLSHLQNFKDFTEICNDVYSFPLFTPAFCKEVIEVMDKANLWSKGGDSYFDPRIGGVESYPTQDTQ----YEVGLDKQWHYVVFNYVAPFVRHLYNNYKTKDIN-LAFVVKYDMQSELAPHHD---SSTYTLNIALNEYGKEYT---AGGCEFIRHKF---------IWQGQKVGYATIHA-GKLLAYHRALPITSGK-RYILVSFVN................................................................................................................................................................................................................................................................................................................................................................................................................ 229
18 -20.6005c5t_A mol:protein length:228 Prolyl 4-hydroxylase  ali model follow..  11  2....GSSSSGLVPRGSHMEGFETSDRPGVCDGKY-YEKIDGFLSDIECDVLINAAIKKGLIKSEVGGATENDPIKLDPKSRNSEQTWFMPGEH--------VIDKIQKKTREFLNSKKHCIDKYDVQVARYKPGQYYYHHYDGDDCDDARLATLMVYLKA---EEGGGGETDFP---------TLKTKIKPKKGTSIFFRKLYKETLHAGLPVKSG-EKIIANQWIRAVK............................................................................................................................................................................................................................................................................................................................................................................................................. 222
19 -18.7005iax_A mol:protein length:226 Procollagen-Proline Dioxygenase  ali model follow..  10  28....................DREIQIISKFEEPL-IVVLGNVLSDEECDELIELSKSKLARS-------KVGSSRDVNDIRTSSGAFLDDNELTAKIEKRI---------SSIMNVPASHGEGLHI--LNYEVDQQYKAHYDYFAEHSRRISTLVMYLN---DVEEGGETFF----------PKLNLSVHPRKGMAVYFESLNELTLHGGAPVTKG-EKWIATQWVRRGT............................................................................................................................................................................................................................................................................................................................................................................................................. 215
20 -18.7002jij_A mol:protein length:233 PROLYL-4 HYDROXYLASE  ali model follow..  8  1..........MMVGFGELKEEWRGEVVHLSWSPR-AFLLKNFLSDEECDYIVEKARPKMVKSSVVDNESGKSVDSEIRTSTG-------------TWFAKGEDSVISKIEKRVAQVTMIPLENHELQVLHYHDGQKYEPHYDYFHDPV-RVVTMLMYLT---TVEEGGEAEQKVTGDGWSECAKRGLAVKPIKGDALMFYSNDPASLHGSCPTLKG-DKWSATKWIHVAP............................................................................................................................................................................................................................................................................................................................................................................................................. 222
21 -17.8004xaa_A mol:protein length:223 Putative oxygenase  ali model follow..  10  1.........MTTATLDRAAAIERFRRD-------GFANAGPVLAPDAIARLKAGAERLITRFTDEGLRSDDYWNFPVEGDERPVLYRVHNLEKQDWERDLLHREELAQLAAAFVD-GPVVPTAYALVLKEPYRAAEVPWHRDRVNVGPRTVCNLSICLDD--AGPHNGCLEAVPGSHLKVRATGPVVPVPVSQGDVVVH---DVRLVHGSGPNANGSWRRTIVIEYADPA............................................................................................................................................................................................................................................................................................................................................................................................................. 218
22 -17.1003bvc_A mol:protein length:212 Uncharacterized protein Ism_01780  ali model follow..  10  7..............................VTRLYHAPLSDHGPAIDAEEMESSCYAIAEDDEAGQGWCEENGYPGYTSYASLTDLPWRF-PIFADLVKSL-DAHVAAFAEDLEDLDGRALELEDLWINILPEGGSHASHI-----HPHSVISGTTYVS----PGGTSALKLEDPRHTARDELRQFIYVTPAVGDVLLW---ESWLRHEVPMNMSEDDRISVS.................................................................................................................................................................................................................................................................................................................................................................................................................... 198
23 -16.9005m0t_A mol:protein length:294 Alpha-ketoglutarate-dependent non-heme iron oxygenase EasH  ali model follow..  13  2....PTITETSKPTLRRIPRSAGDEAIFQVLQEDGVVVIEGFMSADQVRRFNGEIDPHMKQWELGQKSYQESYLAGMRQLSSLPLFSKLFRDEL------MNDELLHGLCKRLFGPESGDYWLTTSSVLETEPGY--ELHREH-RQSPESMLNFLTALT-DFTAENGATRVLWEDFSAPPPKADTAIPAVMNPGDAVLF---TGKTLHG-KNNTTDFLRRGFPLIMQSCQFTPVEASVALPRELVETMTPLAQKM.................................................................................................................................................................................................................................................................................................................................................................................... 258
24 -16.8002rg4_A mol:protein length:216 Uncharacterized protein  ali model follow..  10  2...................SLAQIKSLF--ATRLYHAPLSEHGPALDPAEFAASCYSIAEDDDAGQEWCEREGYPGYTS-YASLTDLPWRFPIFADLVKSL-DAHVAAFAEDLEELDGKALRLEDIWINILPEGGVHGSHI-----HPHSVISGTTYVA----PEGTSALKLEDRRKGAREELRTFRSVAPKVGDVLLW---ESWLRHEVPMNMAEEDRISVS.................................................................................................................................................................................................................................................................................................................................................................................................................... 202
25 -16.6004nao_A mol:protein length:326 Putative oxygenase  ali model follow..  9  7MTSQHQEHTGT-KRFSIQSDPVEIHRAIVED---GVAIIEGFLTPEQVQKLNKDVDAPLKADREQLKFKADKKDDPHFWLADFIPDHVARVHNLHCFRHEILNHELLHKICRLTFEESGDYWLGYGAVIENGPGT----HRDQ-PDAPEGMLNFFTALTD---DAETGKTQYILGSNKEPDADHPIEYVGLKPGDTTIV---SGKITHRGSDNRSDKMRRAMPIMIIPSILTPFDATCHLSRELVETMTPLAQKM.................................................................................................................................................................................................................................................................................................................................................................................... 270
26 -16.3005zm2_A mol:protein length:306 Dioxygenase andA  ali model follow..  9  19............RRVNASQGSDAAYQILQED---GCVIVEQVICPNIIAKISDDVNRVMDKATIGAKKGEQTHIINMHNRTIHMGDLVLTSKTYRD--ELLNLPFAHEVLEKVFKKDSGDYWLNMGNILNMLPGA--RPHRDD-ATSPDLMINITFPLN-EFRHDNGGTLLL--PNADFYANAEDLPAAEMQVGDALIF---TGKCVHGGGANRSDKPRIGLALAAQPGYLTPRESNVNVPRDIVETMTPLAQRM.................................................................................................................................................................................................................................................................................................................................................................................... 267
27 -16.2002a1x_A mol:protein length:308 Phytanoyl-CoA dioxygenase  ali model follow..  10  8SFHPQQFQYTLDNNVLTLEQRKFYEEN-------GFLVIKNLVPDADIQRFRNEFEKICRKEVKPLGLTVMRDVTISKSEYAPSEKMITKVQDFQELFRYCTLPEILKYVECFTG-PNIMAMHTMLINKPPDSGKKTSRHPLHQDRPSDLIVCAWTAMEH--ISRNNGCLVVLPGTHKDYEENKARVHLVMEKGDTVFF---HPLLIHGSGQNKTQGFRKAISCHFASAD............................................................................................................................................................................................................................................................................................................................................................................................................. 256
28 -15.1004y5s_A mol:protein length:315 Verruculogen synthase  ali model follow..  7  3.....EFTVDSKPQLQRLAADADVDRMCRLLEEDGAFILKGLLPFDVVESFNRELDVQMAIPPPKGERLHFKYVPNVATTCPTFRNTVLINPVIHAICEAYFQRTGDYWLSAAFLR------------EIESGMPAQPFHRDD-PLEAPPVSLSVIFPLTEFTEENGATEVIHRWTEVGTPERDQAVLATMDPGDVLIV---RQRVVHGGNRTTAGKPRRVVLAYFNSVQLTPFETYRTMPREMVESMTVLGQRM.................................................................................................................................................................................................................................................................................................................................................................................... 257
29 -15.0004xcb_A mol:protein length:261 oxidase/hydroxylase  ali model follow..  9  4............VPALTREQLYIFDTT-------GFLVIPGVFGSGEVESFRSELERLDTVDPGFPRTRRYPDLPAASPV----FARLALDDRLLAPVRDVVNQPLRLLEGYGLRRTKDSVLYLHGGNSELLDLGDRQVGRDHDGKLYCPYVKALVYLSDIQSPEDGS-FCYVQGSHKADSGFPTLSDVFVRSGDVLLL---NEALMHGTRRKLTEGDRLLTAFGYGPTFFTEWRELDAETADLRGAGYVDHDVEEDFV................................................................................................................................................................................................................................................................................................................................................................................ 260
30 -15.0005ybl_A mol:protein length:314 Multifunctional dioxygenase ausE  ali model follow..  10  8LVPRGSHMPSRLQKFPATAPADEIYAAFKED---GCVIIEGFVPPDQMARFSQEIQPAMEKIQVQVT--RVKRFSKLVTTSPTFRHEILENDLMHELLQRVFSKPGEGMGYHFNDTMVIEVQPGAPAQRLHRDQELYPWWNSMGPDAPECLVNFFCAVTP---TVENGATRLVPATDCPQYGKIDSVPAIMQPGDCYMM---SGKVIHG-HNATLSDQRRALAFST................................................................................................................................................................................................................................................................................................................................................................................................................. 243
31 -14.7005y7t_B mol:protein length:315 Iron/alpha-ketoglutarate-dependent dioxygenase asqJ  ali model follow..  8  1MMTSKDHVKSQIPRLSAINDLHKIWPTVEEH---GAAIIESFLSLDIVRRLNEEVDPFVKIEPIPAAKTKDHPNHVLSTTTRLVNVLAPISKAYREDV--LNSKVLHRICSDAFHVYGDYWVLMGAVMELAPSNPAQPLHRDMLKPDAPATSINFLVALSPFTAENGATHVIHKWQNLSNVSMDATVRALMNPGDALLI---TDSTIHC-AETTGTETRRLLTITMGISQLTPLESNLAVPRPVIESLTPLAQRL.................................................................................................................................................................................................................................................................................................................................................................................... 260
32 -14.7004xab_A mol:protein length:252 EvdO2  ali model follow..  7  1......MDAMEVVGTIDHRDREEFRSR-------GFAILPQVASESEVAWLRQAYDRLFVRRATPGAEDFYDIAGQRDREGPPLLPQIIKPEKYVPLLDSPHFARCRSIASAFLDMEEELEFYGHAILKPPRYGAPTPWHQDEA-RWRRRGLSIWTTLDE--ATVESGCLHYLPGGHRDDVDPTSAVACPLAPGGAVVH---DFRTPHYAGPNLTDQPRRAYVLVFMSAP............................................................................................................................................................................................................................................................................................................................................................................................................. 237
33 -14.3005ybm_A mol:protein length:314 PrhA  ali model follow..  7  8LVPRGSHMPPRLQRFPATASADEIFAAFQED---GCVVIEGFISPEQVARFSQEVDPAMEKIPVEVT--RTKRFSKCVIASPTFRNEIIESDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQPGAPAQRLHRDQELYPWWNSMGPAGPECVINFFCAVTP---TEENGATRLVPERDCPQFGKIETVPAIMQPGDCYLM---SGKVIHG-HNATTTDRRRALALAI................................................................................................................................................................................................................................................................................................................................................................................................................. 243
34 -14.2003emr_A mol:protein length:310 EctD  ali model follow..  11  31...........NQAPITKEQLDSYEKN-------GFLQIKNFFSEDEVIDMQKAIFELQDSIKDVASDKVIREPESNDIRSIFHVHQDD-----NYFQDVANDKRILDIVRHLLG-SDVYVHQSRINYKPGFKGKEFDWHSDF---PRMRAISVSIALSD--NYSFNGPLMLIPGSHNYTRIGGGISVPTGKAGSVTLF---ESNTMHGSTSNITPYPRNNLFMVYNSVK............................................................................................................................................................................................................................................................................................................................................................................................................. 270
35 -14.0005nch_A mol:protein length:268 Leucine hydroxylase  ali model follow..  7  2...........GRMQLTADQVEKYKSD-------GYVLLEGAFSPEEVHVMRQALKKDQE---------VQGPHRILEEDGRTVRALYASHTRQSVFDQLSRSDRLLGPATQLLE-CDLYIHQFKINTKRAFGGDSWAWHQDF---PAPRAVNVGVFLSD--VTEFNGPVVFLSGSHQQMVEKHPMVSPKAASGSVMLF---HPEIIHGSAPNISPFARDLLIITYNDVANAPKPAGEPRPEYVIGRDTTPLV...................................................................................................................................................................................................................................................................................................................................................................................... 258
36 -13.9004mhr_A mol:protein length:314 Ectoine hydroxylase  ali model follow..  9  31...........NDAPISARQAAAFDRD-------GYIVLEDIFSADEVAFLQKAAGNLLADPAALDADTIVTEPQSNEIRSIFEIHAQS-----PVMARLAADARLADVARFLLG-DEVYIHQSRLNYKPGFKGREFYWHSDF---PRMRALSMSVLLAE--NTPHNGPLMVIPGSHRELAHRHGIVAPTGKPGTVILF---DCNLMHGSNGNITPFPRANAFLVYNAVSN............................................................................................................................................................................................................................................................................................................................................................................................................ 270
37 -13.7003nnf_A mol:protein length:344 CurA  ali model follow..  9  1MSSGVDLGTYFQSNAMNREQVEQLKQEYEEK---GYCQIKKIFDFSAIKTIQKTLDQAKQESQISKEKVTLKLGG-----IDDIDTNDHAYDLVKYDFVSSFIQEKLALLNYITGKNLMIMH--NALFSVEPNHKGLPWHVGVFTKTEDFGASI-------WTKEHRGGMQYVSTKIFPIKDGYEEDEYNL--GDAFFF---NKYVLHQSVP-GLHKLRRAFVIRLVDYDT............................................................................................................................................................................................................................................................................................................................................................................................................ 271
38 -13.6002opw_A mol:protein length:291 PHYHD1 protein  ali model follow..  7  2.............ACLSPSQLQKFQQD-------GFLVLEGFLSAEECVAMQQRIGEIVAEMDVPLHCRTEFSTQEEEQLRAQGSTDYFLSSG-PVFKSITHSFKVQTLARSLGL-QMPVVVQSMYIFKQPHFGGEVSPHQDAS-EPLGRVLGVWIAVED--ATLENGCLWFIPGSHTSARDNSLFVPTPVQRGALVLI---HGEVVHKSKQNLSDRSRQAYTFHLMEAS............................................................................................................................................................................................................................................................................................................................................................................................................. 268
39 -13.6005ep9_A mol:protein length:305 SnoN,Epimerase SnoN  ali model follow..  7  1MARDQETEPGVPADLPAESDPAALERLAARYRRDGYVHVPGVLDAGEVAEYLAEARRLLA---------HEESVRWGSGAGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGLRLFKLEVLLKENKEKDASVPTAPHHDAF-STAGTALTAWVALVD---PVERGCMTFVPGSHLPGEIWMPRVTVPLRAGDCTFH---HARTVHSAGANSTDEPRLSTSAVYMDAT............................................................................................................................................................................................................................................................................................................................................................................................................. 240
40 -13.5004xbz_A mol:protein length:334 EvdO1  ali model follow..  9  25..VNRIAECDIRRTGLLPEHVTAFRRQ-------GVLVVRGLLTPQELADVQEAGRALIDRAWSTRSMEDTVWTLEPDQPGAAPVRIEYVVDKARPIAMLAGHPLLLRIMEQLVG-PNLIPTWDSMVFKTPAGAPRLAWHRDA---GAGRVIDAGIYLDP---APEDNCVWCIPESNYSEWDTTGAVPAVMQPGDLLLH---NILTLHG-APAVVGKQRRVIYFEYRPAE............................................................................................................................................................................................................................................................................................................................................................................................................. 259
41 -13.3002fd8_A mol:protein length:211 Alkylated DNA repair protein alkB  ali model follow..  10  1...........................MQEPLAAGAVILRRFAFNAAEQLIRDINDYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQR-----AATAAGYPDFQPDACLI--NRYAPGAKLSLHQDKDEPDLRAPIVSVSL----------GLPAIFQ---GGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGDCRYNLT--FRQAGKKEN......................................................................................................................................................................................................................................................................................................................................................................................................... 207
42 -13.2004nj4_A mol:protein length:250 RNA demethylase ALKBH5  ali model follow..  12  8..GTENLYFQSMPERSDYEEQQLQKEEEARKVK-SGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFSAVINDYQPGGCIVSHVDPIHERPIVSVSFFSDSALCFGCK---------FQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEIHCIRPQDIKERRAVII.................................................................................................................................................................................................................................................................................................................................................................................................................... 233
43 -13.0004qkb_A mol:protein length:200 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial  ali model follow..  11  3....................VRGSGPSVLSRLQDAAVVRPGFLSTAEEETLSRELEPELRRRRYEYDHWDAAIHGFRETEKSR------------------WSEASMAIMRRVQAAAFGPGQTLSVHVLDLEARGYIKPHVDSIKGATIAGLSL-------------LSPSVMRLVHTQEPGEWLELLLEP--GSLYILRGSARYDFHEILRRIPRGRRISVI.................................................................................................................................................................................................................................................................................................................................................................................................................... 186
44 -13.0002rdn_A mol:protein length:288 1-deoxypentalenic acid 11-beta hydroxylase; Fe(II)/alpha-ketoglutarate dependent hydroxylase  ali model follow..  9  3..HMTNVTGDYTDCTPLLGDRAALDSFYEEH---GYLFLRNVLDRDLVKTVAEQMREGLV----ALGAADPHATLEELTIDSFESVDEVAMHDYVKYDAFWNNPSTIKVFEQVFGSTTIRYYPSQAGSEEPSFHYLTPFHQDGFYIGPNQDFRTF------W-TRESGGVALADGSHREVSEDEHLLHSPMEPGDILLF---HAHMCHKSIPNLSKDPRMSMDTRVQPAKSH........................................................................................................................................................................................................................................................................................................................................................................................................... 256
45 -12.9004lt5_A mol:protein length:327 Naegleria Tet-like dioxygenase  ali model follow..  10  110....................................AYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTADLSQELGQYLSEIVNPQIVSSRTINYLVSLNDSYYYPSTAFNSLKPSNDGHRIRKPHKD---NLDITPSSLFYFGNFQNT---EGYLEL--------TDKNCKVFVQP--GDVLFFK--GNEYKHVVANITSGW-RIGLVYFAHKGSKTKPYYEDTQKNSLKIHKETK........................................................................................................................................................................................................................................................................................................................................................................................ 321
46 -12.7003khb_A mol:protein length:219 Alpha-ketoglutarate-dependent dioxygenase alkB  ali model follow..  10  21..................................GAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQR-----AATAAGYPDFQPDACLI--NRYAPGAKLSLHQDKDEPDLRAPIVSVSL----------GLPAIFQ---GGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGDCRYNLT--FRQAGKKE.......................................................................................................................................................................................................................................................................................................................................................................................................... 219
47 -12.6004nig_A mol:protein length:205 Alpha-ketoglutarate-dependent dioxygenase AlkB  ali model follow..  9  1............................QEPLAAGAVILRRFAFNAAEQLIRDINDYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQR-----AATAAGYPDFQPDACLI--NRYAPGAKLCLHQDKIHPDLRAPIVSVSL----------GLPAIFQFGGLKRNDPLKRLLLEH--GDVVVWGGESRLFYHGIQPLKAGDCRYNLT.................................................................................................................................................................................................................................................................................................................................................................................................................... 197
48 -12.5006EC3 Entity 1(prereleased)  ali follow..  8  235..SAEVCDIVVVGRARLGAQIRRFRED-------GFVNAGPVFADDTIARLKAGAIDLISRFTEHGHVSDDYWNYDVENEAPVLYRIHNLEKQDWAERELLFRPELAELAAAFVG-SPVVPTAFALVLKEPKRAAGVPWHRDRANVAPHTVCNLSICLDT--AGPENGCLEGVPGSHLEIRDGGPRVPVPSKVGDVIVH---DVRLVHGSGPNPSDQWRRTIVIEFANPA............................................................................................................................................................................................................................................................................................................................................................................................................. 457
49 -12.4005epa_A mol:protein length:279 SnoK  ali model follow..  10  6...DPDPGGPTTAENLSKEAVRFYREQ-------GYVHIPRVLSETEVTAFRAACEEVLE---------EGREIWGAGEDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAG-APLRVYSSDILVKEPKRTLPTLVHDDET-NELSATLTAWIALTD--VPVERGCMSYVPGSHLPDYPWQPRVAVPVRAGDVVFH---HCRTVHMAEANTSDSVRMAHGVVYMDAD............................................................................................................................................................................................................................................................................................................................................................................................................. 237
50 -12.4004o61_A mol:protein length:222 RNA demethylase ALKBH5  ali model follow..  13  2.....................QQLQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFSAVINDYQPGGCIVSHVDPIHERPIVSVSFFSDSALCFGCK---------FQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEIHCIRPQDIKERRAVII.................................................................................................................................................................................................................................................................................................................................................................................................................... 209
51 -12.3004npl_A mol:protein length:250 RNA demethylase ALKBH5  ali model follow..  10  2................ESEYEERRDAEARRVKS---IKQASIFTLEECARIEAKIDEVVAKADKGLYREHTVDRAPLRNKQLEKRGPGQERLYSKGEVDDIPDWVHELVIDRLVTHGVIPEGFVNAVINDYQPGGCIVSHVDPIHERPIVSVSFFSDSALCFGCK---------FLFKPIRVSEPVLHLPVRRGSVTVLSGYAADDIHCIRPQDIKERRAVII.................................................................................................................................................................................................................................................................................................................................................................................................................... 212
52 -12.0005xeg_A mol:protein length:231 Oxidoreductase, 2OG-Fe oxygenase family protein, putative, expressed  ali model follow..  13  12..................................GMVLLKKFLKHDIIRRCQKLGIGSGGFYTPGYRDGGKLSLQNSRSYGDTRPFDGAQPPSIPEVFSKIVKDAIQASNEFLRQKARPANDVEELPVNFYTSSGKLGLHQDKDETKSLHKGLPVVSFS--------GDTAEF----GDVNDVDKASKVDLESGDVLIFGGKSRLIFHGVSRIKPKPGRLNLT.................................................................................................................................................................................................................................................................................................................................................................................................................... 227
53 -10.6002fct_A mol:protein length:313 syringomycin biosynthesis enzyme 2  ali model follow..  9  2.......SHMSKKFALTAEQRASFEKN-------GFIGPFDAYSPEEMKETWKRTRLRLL------DRSAAAYQDLDAISGGTNIANYDRHLDDDFLASHICRPEICDRVESILGPNVLCWRTE---FPKYPGDEGTDWHQADENEEFGGTITVWTAFTD--ANIANGCLQFIPGTQNSKPDEASAVPMQMKAGQFIIF---WSTLMHASYP-ESQEMRMGFASRYVPSF............................................................................................................................................................................................................................................................................................................................................................................................................. 262
54 -10.6004mg2_A mol:protein length:205 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2  ali model follow..  16  14.....................................SYTVLFGKAEADEIFQELEKEVEYFTGALARVQVADAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVL--------------INRYKDGDHICEHRD--DERELAPGSPIASVS--------GASRDFDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWHSLPV-KVLAPRVNLT.................................................................................................................................................................................................................................................................................................................................................................................................................... 198
55 -10.6003rzm_A mol:protein length:206 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2  ali model follow..  16  14.....................................SYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVL--------------INRYKDGDHICEHRD--DERELAPGSPIASVS--------GASRDFDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWHSLPV-KVLAPRVNLT.................................................................................................................................................................................................................................................................................................................................................................................................................... 198
56 -10.5002iuw_A mol:protein length:238 ALKYLATED REPAIR PROTEIN ALKB HOMOLOG 3  ali model follow..  9  38.....................................LYPGFVDVKEADWILEQLCQDVPWKQRTGIRED--ITYQQPRLTAWYGELPYTYSRITMEPNPHWHPVLRTLKNRIEENTGHTFNSL---CNLYRNEDSVDWHSDDEPSLGRCPIIASLSF---------GATRTFPPEENGDYTYVERVKIPLDHGTLLIMEGATQADWHRVPK-HSREPRVNLT-W.................................................................................................................................................................................................................................................................................................................................................................................................................. 232
57 -10.5004mgt_A mol:protein length:205 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2  ali model follow..  16  14.....................................SYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVL--------------INRYKDGDHICEHRD--DERELAPGSPIASVS--------GASRDFDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWHSLPV-KVLAPRVNLT.................................................................................................................................................................................................................................................................................................................................................................................................................... 198
58 -10.2003h8o_A mol:protein length:209 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2  ali model follow..  16  16.....................................SYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVL--------------INRYKDGDHIGEHRD--DCRELAPGSPIASVS--------GASRDFDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWHSLPV-KVLAPRVNLT.................................................................................................................................................................................................................................................................................................................................................................................................................... 200
59 -10.1003rzg_A mol:protein length:209 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2  ali model follow..  16  16.....................................SYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVL--------------INRYKDGDHICEHRD--DERDLAPGSPIASVS--------GASRDFDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWHSLPV-KVLAPRVNLT.................................................................................................................................................................................................................................................................................................................................................................................................................... 200
60 -9.9203thp_A mol:protein length:345 Alkylated DNA repair protein alkB homolog 8  ali model follow..  10  99.....................VQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNS---QKSLKHRRVKHFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPAHIDTHSEDEIVSLSLGSEIVMDFKHPDGIAVPVM---------------LPR--RSLLVMTGESRYLWHGITCLSKRGLRTSFT.................................................................................................................................................................................................................................................................................................................................................................................................................... 308
61 -9.7003gja_A mol:protein length:319 CytC3  ali model follow..  10  8...........ANFTFSPEEVARFERD-------GYIGPVKIFEPEEMTRRWNIIRRQLL---------DRSLAIYPDSNGKANISNYDRHLDIDLLAEHIMRPEIVDRVGSLIGRNLLCWRSE---FPKYQGDEGTDWHQAA-RPAFIGTITVWTAFTH--STEQNGCLQLMPGTHTWKPDESQAYPMVLKPGEAVIF---WSNTMHASLPHTGSKTRMGFAARYVPTQ............................................................................................................................................................................................................................................................................................................................................................................................................. 264
62 -9.3406fxk_A mol:protein length:718 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3  ali model follow..  10  507LWQIFDNPVDWKEQYIHENYSRALEGEGIVEQPCPDVYWFPLLSEQMCDELVAEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVG----YEDQWLQLLRTYVGPMTESLFPGYHTKARAVMNFVVRYRPDESLRPHHD---SSTFTLNVALNHKGLDYE---GGGCRFLRYD---------CVISSPRKGWALLHP----THYHEGLPTTWGT-RYIMVSFVDPAA............................................................................................................................................................................................................................................................................................................................................................................................................. 717
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A.; RIKEN GER Group; GSL Members. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res. 2003 Jun;13(6B):1376-88.