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Query: 3lfm_A mol:protein length:495 Protein fto, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGSSSSGLVPRGSHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKPLast
1 -151.0003lfm_A mol:protein length:495 Protein fto  ali model  100  1MGSSSSGLVPRGSHMTPKDDEFYQQWQLKYPKLILREASSVSEELHKEVQEAFLTLHKHGCLFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGSNIKHTEAEIAAACETFLKLNDYLQIETIQALEELAAKEKANEDAVPLCMSADFPRVGMGSSYNGQDEVDIKSRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVDRSAVAVYSYSCEGPEEESEDDSHLEGRDPDIWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGSQPRFSSTHRVAECSTGTLDYILQRCQLALQNVCDDVDNDDVSLKSFEPAVLKQGEEIHNEVEFEWLRQFWFQGNRYRKCTDWWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLLEAKP 489
2 -56.9003rzm_A mol:protein length:206 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2  ali model follow..  20  21.............................................KAEADEIFQELEKEVEYFTARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPW--------------------------------------------------------------IPVLERIRDHVSGVTGQTFNFVLINR--------------YKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRGKSP-----------SRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKAPRVNLTFRKILLTA................................................................................................................................................................................. 206
3 -56.8003rzg_A mol:protein length:209 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2  ali model follow..  20  23.............................................KAEADEIFQELEKEVEYFTGAVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPW--------------------------------------------------------------IPVLERIRDHVSGVTGQTFNFVLINR--------------YKDGSDHICEHRDDERDLAPGSPIASVSFGASRDFVFRHKDSRGKSP-----------SRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKAPRVNLTFRKILLTK................................................................................................................................................................................. 208
4 -56.7004mgt_A mol:protein length:205 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2  ali model follow..  20  21.............................................KAEADEIFQELEKEVEYALARVQVFGKWHSVPAKQATYGDAGLTYTFSGLTLSPKPW--------------------------------------------------------------IPVLERIRDHVSGVTGQTFNFVLINR--------------YKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRGKSP-----------SRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKAPRVNLTFRKILLG.................................................................................................................................................................................. 205
5 -56.5003h8o_A mol:protein length:209 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2  ali model follow..  20  23.............................................KAEADEIFQELEKEVEYFTGAVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPW--------------------------------------------------------------IPVLERIRDHVSGVTGQTFNFVLINR--------------YKDGSDHIGEHRDDCRELAPGSPIASVSFGASRDFVFRHKDSRGKSP-----------SRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKAPRVNLTFRKILLTK................................................................................................................................................................................. 208
6 -56.0004mg2_A mol:protein length:205 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2  ali model follow..  20  21.............................................KAEADEIFQELEKEVEYALARVQVAGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPW--------------------------------------------------------------IPVLERIRDHVSGVTGQTFNFVLINR--------------YKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRGKSP-----------SRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKAPRVNLTFRKIL.................................................................................................................................................................................... 203
7 -54.7002iuw_A mol:protein length:238 ALKYLATED REPAIR PROTEIN ALKB HOMOLOG 3  ali model follow..  20  1MGSSSSGLVPRGSHMRVIDR--EGVYEISLSPTGVSRVCLYPGFVDVKADWILEQLCQDVPWKQRTGIREDITYQQPRLTAWYGEL--PYTYSRITMEPNP-------------------------------------------------------------HWHPVLRTLKNRIEENTGHTFNSLLCNL--------------YRNEKDSVDWHSDDEPSLGRCPIIASLSFGATRTFEMRKKPPPEENGD----------YTYVERVKIPLDHGTLLIMEGATQADWQHRVPKEYEPRVNLTFRTVYPD.................................................................................................................................................................................. 226
8 -29.3004nj4_A mol:protein length:250 RNA demethylase ALKBH5  ali model follow..  12  49.............................................QDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFF--GEGYTYGAQLQKRGP---------------------------------------------GQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVIND--------------YQPG-GCIVSHVDPIHIFER--PIVSVSFFSDSALCFGCKFQFKPIRV------------SEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDERRAVIILRKTRLDA................................................................................................................................................................................. 241
9 -29.2005xeg_A mol:protein length:231 Oxidoreductase, 2OG-Fe oxygenase family protein, putative, expressed  ali model follow..  11  11..............................PGMVLLKKFLKHDDQVDIIRRCQKLGIGSGGFYTPGYRDGGKLSLQMMCLGKNWDPN-SRSY----------------------------------------GDTRPFDGAQPPSIPEVFSKIVKDAIQASNEFLRQKARPANDVEELPPLSPDICLVNF--------------YTSSGKLGLHQDKDEPSLHKGLPVVSFSLGDTAEFLYGDVNDVDK------------------ASKVDLESGDVLIFGGKSRLIF-HGVSR-RPGRLNLTFRQ...................................................................................................................................................................................... 230
10 -29.2004o61_A mol:protein length:222 RNA demethylase ALKBH5  ali model follow..  13  93................................................................................................................................................................PEWVHQLVIQKLVEHRVIPEGFVNSAVIND--------------YQPG-GCIVSHVDPIHIFER--PIVSVSFFSDSALCFGCKFQFKPIRV------------SEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDERRAVIILRKTRLDA................................................................................................................................................................................. 217
11 -28.7003khb_A mol:protein length:219 Alpha-ketoglutarate-dependent dioxygenase alkB  ali model follow..  9  1...............GPHMLDLFAD-AEPWQEPLAAGAVILRRFAFNAAEQLIRDINDQSPFRQMVTPGGYTMSVAMTNCGHLGTHRQGYLYSPIDPQTNKPWPAMPQ-------------------------------------------------------SFHNLCQRAATAAGYPDFQPDACLINR--------------YAPGAKLSLHQDKDEPDLRA--PIVSVSLGLPAIFQFGGLKRNDP------------------LKRLLLEHGDVVVWGGESR-LFYHGIQP-IDCRYNLTFRQAGKKE................................................................................................................................................................................. 219
12 -28.6004npl_A mol:protein length:250 RNA demethylase ALKBH5  ali model follow..  12  1.................DESEYEERRDAEARRVK--SGIKQASIFTLEECARIEAKIDEVVAKADKGLYREHTVDRAPLRNKY---GEGYTYGAQLEKRGP---------------------------------------------GQERLYSKGEVDDIPDWVHELVIDRLVTHGVIPEGFVNSAVIND--------------YQPG-GCIVSHVDPIHIFER--PIVSVSFFSDSALCFGCKFLFKPIRV------------SEPVLHLPVRRGSVTVLSGYAADDITHCIRPQDERRAVIILRKTRADAPRLDSNSLSPSIVSPKRRHILKAKRSHRKA................................................................................................................................................... 250
13 -27.8002fd8_A mol:protein length:211 Alkylated DNA repair protein alkB  ali model follow..  12  11.......................................ILRRFAFNAAEQLIRDINDVAS-FRQMVTPGGYTMSVAMTNCGHLG-RQGYLYSPIDPQTNKPWP----------------------------------------------------------AMPQSFHNLCQRAATAAGFQPDACLINR--------------YAPGAKLSLHQDKDEPDLRA--PIVSVSLGLPAIFQFGGLKRND------------------PLKRLLLEHGDVVVWGGESR-LFYHGIQP-IDCRYNLTFRQAGKKEN................................................................................................................................................................................ 207
14 -26.8004nig_A mol:protein length:205 Alpha-ketoglutarate-dependent dioxygenase AlkB  ali model follow..  12  88.......................................................................................................................................................................LCQRAATAAGYPDFQPDACLINR--------------YAPGAKLCLHQDKIHPDLRA--PIVSVSLGLPAIFQFGGLKRNDP------------------LKRLLLEHGDVVVWGGESR-LFYHGIQP-IDCRYNLTFRQAGKKE................................................................................................................................................................................. 205
15 -26.2004qkb_A mol:protein length:200 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial  ali model follow..  12  67................................................................................................................................................................SEASMAIMRRVQAAAFGPGQTLLSSVHVLD--------------LEARG-YIKPHVDSIKFCGA--TIAGLSLLSPSVMRLVHTQEPGE------------------WLELLLEPGSLYILRGSARYDFSHEILRDEGRRISVICRSLPEGMGPGES............................................................................................................................................................................ 199
16 -21.6003thp_A mol:protein length:345 Alkylated DNA repair protein alkB homolog 8  ali model follow..  11  115.......................................VVEEIISSEEE---KMLLESVDWTEDTDNQNSQKSLKHRRVKHFGY---EFHYENNNV---------------------------------------------------------DKDKPLSGGLPDICESFLEKWLRKIKHKPDQMTINQ--------------YEPGQ-GIPAHIDTHSAFED--EIVSLSLGSEIVMDFKHPDG--------------------IAVPVMLPRRSLLVMTGESRYLWTHGITCRKGLRTSFTFRKVRQTPCNCSY-PLVCDSQRKENLYFQGLE......................................................................................................................................................... 339
17 -9.7404y4r_A mol:protein length:454 Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66  ali model follow..  10  1.GGEPAWDSPLRRVLAELNRI---------------------PSSRRRAARLFEWLIAPMPPDH--------------------------------FYRRLWEREAVLVRRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGLCPQAFSTTVWQFLAVLQEQFGSMAGSNVY---------------LTPPNSQGFAPHYDDI--------AFVLQLEGRKLWRVYRPRVPTEELALTSSPNFSQDDLGEPVLQTVLEPGDLLYF-----RGFIHAECQDGVHSLHLTLS-TYQRNTWGDFLEAILPLAVQAAMEENVEFRRGLTAFMEKVRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGGGGQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYH-------LEEPKCLEIYPQQADAMELLLGSYPEFVRLPEDQLSLATTLKGLLLTKMP 450
18 -9.0203w20_A mol:protein length:273 Putative uncharacterized protein  ali model follow..  5  1........................................MQHTYPAQLMRFGTAARAEHMTIAAAIHALDADEADAIVMDIVPDGERDAWWDDEGFSSSPFTKNAHHAGIVATSVT--------LGQLQREQGDKLVSKAAEYFGIACRVNDGLRTTRFVRLFSDALDAKPLTIGHDYEVEFLLATRRVYEP------------FEAPFNFAPHCDDPRQLGGFLTIQGADNDAG-DNRPESRAALDEMHAEYRETGAIAALERAAKIMLKPQPGQLTLF----QSKNLHAIERCTSTRRTMGLFLIHTEDGWRMF............................................................................................................................................................................ 272
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A.; RIKEN GER Group; GSL Members. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res. 2003 Jun;13(6B):1376-88.