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Query: 4i6t_A mol:protein length:82 Regulatory protein, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80
# Score Template Links and tools%idFirst GSHMESFLLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRAYISGIERNSRNLTIKSLELIMKGLEVSDVVFFEMLIKEILKHDLast
1 -48.7004i6t_A mol:protein length:82 Regulatory protein  ali model  100  1GSHMESFLLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRAYISGIERNSRNLTIKSLELIMKGLEVSDVVFFEMLIKEILKHD 82
2 -48.7004fn3_A mol:protein length:82 Regulatory protein  ali model follow..  97  1GSHMESFLLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRTYISGIERNSRNLTIKALELIMKGLEVSDVVFFEMLIKEILKHD 82
3 -48.4004i6u_A mol:protein length:82 Regulatory protein  ali model follow..  97  1GSHMESFLLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRTFISGIERNSRNLTIKSLELIMKGLEVSDVVFFEMLIKEILKHD 82
4 -48.3004f8d_A mol:protein length:82 Regulatory protein  ali model follow..  97  1GSHMESFLLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRTYISGIERNSANLTIKSLELIMKGLEVSDVVFFEMLIKEILKHD 82
5 -48.0004ia8_A mol:protein length:82 Regulatory protein  ali model follow..  97  1GSHMESFLLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRTAISGIERNSRNLTIKSLELIMKGLEVSDVVFFEMLIKEILKHD 82
6 -45.4003g5g_A mol:protein length:99 Regulatory protein  ali model follow..  98  13.SHMESFLLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRTYISGIERNSRNLTIKSLELIMKGLEVSDVVFFEMLIKEILKHD 93
7 -44.7003fya_A mol:protein length:99 Regulatory protein  ali model follow..  97  13.SHMESFLLSKVSFVIKKIRLEKGMTQEDLAYKSNLDATYISGIERNSRNLTIKSLELIMKGLEVSDVVFFEMLIKEILKHD 93
8 -43.0002b5a_A mol:protein length:77 C.BclI  ali model follow..  35  4....EIEIKRKFGRTLKKIRTQKGVSQEELADLAGLHRTYISEVERGDRNISLINIHKICAALDIPASTFFRKMEEE..... 76
9 -42.4001y7y_A mol:protein length:74 C.AhdI  ali model follow..  30  3SHHDHYADLVKFGQRLRELRTAKGLSQETLAFLSGLDRSYVGGVERGQRNVSLVNILKLATALDIEPRELFC.......... 74
10 -40.2003vk0_A mol:protein length:114 Transcriptional regulator  ali model follow..  27  15....EQDLRAVLAYNMRLFRVNKGWSQEELARQCGLDRTYVSAVERKRWNIALSNIEKMAAALGVAAYQLLLPPQER..... 87
11 -37.1002ewt_A mol:protein length:71 putative DNA-binding protein  ali model follow..  18  1...MSSEYAKQLGAKLRAIRTQQGLSLHGVEEKSQWKAVVVGSYERGDRAVTVQRLAELADFYGVPVQELLP.......... 71
12 -35.9003f6w_A mol:protein length:83 XRE-family like protein  ali model follow..  15  5.KTIHNARYQALLDLLLEARSAAGITQKELAARLGRPQSFVSKTENAERRLDVIEFMDFCRGIGTDPYALLSKLEAMTPS.. 83
13 -34.5003kxa_A mol:protein length:141 Putative uncharacterized protein  ali model follow..  23  56....DKIALKAGGETFVSLRMKKGFTQSELATAAGLPQPYLSRIENSKQSLQDKTVQKLANALGVSPLEVRAAFERRYEYME 133
14 -34.3003f51_A mol:protein length:117 Clp gene regulator (ClgR)  ali model follow..  21  22....EPLLREALGAALRSFRADKGVTLRELAEASRVSPGYLSELERGRKEVSSELLASVCHALGASVADVLIEAAGS..... 94
15 -33.5003qq6_A mol:protein length:78 HTH-type transcriptional regulator sinR  ali model follow..  33  3.........SMIGQRIKQYRKEKGYSLSELAEKAGVAKSYLSSIERNLQNPSIQFLEKVSAVLDVSVHTLLDEKHET..... 71
16 -33.2005woq_A mol:protein length:120 Transcriptional regulator ClgR  ali model follow..  17  3...MTALLREVIGDVLRNARTDQGRTLREVSDAARVSLGYLSEVERGRKEASSELLSAICDALDVPLSRVLTDAGESMARRE 81
17 -32.8002ef8_A mol:protein length:84 Putative transcription factor  ali model follow..  20  1.PTIHDHRYRCLVQLLTKLRKEASLSQSELAIFLGLSQSDISKIESFERRLDALELFELLEVVASRLGLPMDILLKDTYES. 80
18 -32.1004z5h_A mol:protein length:72 Antitoxin HipB  ali model follow..  27  4....KIYSPTQLANAMKLVRQQNGWTQAELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDA.......... 71
19 -31.7003b7h_A mol:protein length:78 Prophage Lp1 protein 11  ali model follow..  14  2.....KTDGEFVSEHLMELITQQNLTINRVATLAGLNQSTVNAMFEGRKRPTITTIRKVCGTLGISVHDFFDFPPYNEVEK. 78
20 -31.6003ivp_A mol:protein length:126 Putative transposon-related DNA-binding protein  ali model follow..  22  11.........RALGLAIKEARKKQGLTREQVGAMIEIDPRYLTNIENKGQHPSLQVLYDLVSLLNVSVDEFFLPASSQVKST. 82
21 -31.0002wiu_B mol:protein length:88 HTH-TYPE TRANSCRIPTIONAL REGULATOR HIPB  ali model follow..  24  3.SFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDAKNASPESTEQ 83
22 -30.9002ofy_A mol:protein length:86 Putative XRE-family transcriptional regulator  ali model follow..  11  7.TAEELERGQRLGELLRSAR--GDMSMVTVAFDAGISVETLRKIETGRATPAFFTIAAVARVLDLSLDDVAA.......... 76
23 -30.7003eus_A mol:protein length:86 DNA-binding protein  ali model follow..  20  5.KTLRTPEHVYLCQRLRQARLDAGLTQADLAERLDKPQSFVAKVETRERRLDVIEFAKWMAACEG................. 68
24 -30.1001b0n_A mol:protein length:111 PROTEIN (SINR PROTEIN)  ali model follow..  30  1..........MIGQRIKQYRKEKGYSLSELAEKAGVAKSYLSSIERNLQNPSIQFLEKVSAVLDVSVHTLLDEKHETEYDGQ 73
25 -29.6005k98_B mol:protein length:91 Antitoxin HipB  ali model follow..  24  6.SFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDTKNASPESTEQ 86
26 -29.4004pu3_D mol:protein length:118 Toxin-antitoxin system antidote transcriptional repressor Xre family  ali model follow..  17  42.........QSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGE-DVYISTVFKILDGLGIDIVSAQTSDTET..... 108
27 -28.8001y9q_A mol:protein length:192 transcriptional regulator, HTH_3 family  ali model follow..  28  2.SLTDVMFKSQIANQLKNLRKSRGLSLDATAQLTGVSKAMLGQIERGESSPTIATLWKIASGLEASFSAFFA.......... 72
28 -28.6001rio_A mol:protein length:98 Repressor protein CI  ali model follow..  20  9.TQEQLEDARRLKAIYEKKKNELGLSQESVADKMGMGQSGVGALFNGINALNAYNAALLAKILKVSVEEFSPSIAREIYE.. 87
29 -28.1002xiu_A mol:protein length:66 CYLR2  ali model follow..  25  1..........MIINNLKLIREKKKISQSELAALLEVSRQTINGIEKNKYNPSLQLALKIAYYLNCPLEDIFQWQPE...... 66
30 -28.0001utx_A mol:protein length:66 CYLR2  ali model follow..  25  1..........MIINNLKLIREKKKISQSELAALLEVSRQTINGIEKNKYNPSLQLALKIAYYLNTPLEDIFQWQPE...... 66
31 -27.9003kz3_A mol:protein length:80 Repressor protein CI  ali model follow..  19  3.TQEQLEDARRLKAIWEKKKNELGLSYESVADKMGMGQSAVAALFNGINALNAYNAALLAKILKVSVEEFSPSIAREIR... 80
32 -27.7005uk3_A mol:protein length:176 Uncharacterized protein  ali model follow..  17  17........RQIMSNQFIKAKESKGLTYQQMAQLLSVNKVWLTSVLHGQNCCDIQLAHRICDTLGISHEYANE.......... 80
33 -27.6002mez_A mol:protein length:106 Multiprotein Bridging Factor (MBP-like)  ali model follow..  20  1.ENAELEIVTDYYKIIKTAREQLGISQQQLAQKLKVSENIVKRFESGKLKPTISQARQLEKILGIKLVTPLENNEESEKEFD 81
34 -27.4001lli_A mol:protein length:92 PROTEIN (LAMBDA REPRESSOR)  ali model follow..  22  8.TQEQLEDARRLKAIYEKKKNELGLSQESLADKLGMGQSGIGALFNGINALNAYNAALLAKILKVSVEEFSPSIAREIYE.. 86
35 -27.4006b9s_A mol:protein length:457 Methylphosphonate synthase  ali model follow..  12  6.DFKPDSYLIRSGNNFLGILNDIKRRPEDAANELGVSIEEINSIISGKQKISPSLIEKAVNIWPVNERDFYIVSDDCSSG.. 84
36 -27.2001zz6_A mol:protein length:198 Hydroxypropylphosphonic Acid Epoxidase  ali model follow..  14  4....TKTASTGFAELLKDRREQVKMDHAALASLLGETPETVAAWENGEGGETLTQLGRIAHVLGTSIGALTPPAGNDLDD.. 80
37 -26.8002k9q_A mol:protein length:77 uncharacterized protein  ali model follow..  17  2..........ELSNELKVERIRLSLTAKSVAEEMGISRQQLCNIEQSETAPVVVKYIAFLRSKGVDLNALFDRIIVNKLE.. 71
38 -26.6001adr_A mol:protein length:76 P22 C2 REPRESSOR  ali model follow..  16  3........TQLMGERIRARRKKLKIRQAALGKMVGVSNVAISQWERSETEPNGENLLALSKALQCSPDYLLKGDLSQTN... 73
39 -26.4001x57_A mol:protein length:91 Endothelial differentiation-related factor 1  ali model follow..  23  7....GDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPRA 84
40 -26.3003lfp_A mol:protein length:98 Csp231I C protein  ali model follow..  18  1..........MLIRRLKDARLRAGISQEKLGVLAGIDEARMNQYEKGKHAPDFEMANRLAKVLKIPVSYLYTPEDD...... 70
41 -26.0004y42_A mol:protein length:156 Cyanate hydratase  ali model follow..  13  3QSLHYSSPRETLTDTIMMAKIRKNLTFEAINQGTGLSLAFVTAALLGQHPLPEQAARVVAEKLDLDEDAIRL.......... 74
42 -25.8006b9r_A mol:protein length:450 Hydroxyethylphosphonate dioxygenase  ali model follow..  14  236.........GDHGAMLRSVMAARLTTVTELADRSGLKTDRVAALCRTPARAEWPELSALAEALGVSVRELLVPHTTTEAD.. 306
43 -25.8004ghj_A mol:protein length:101 Probable transcriptional regulator  ali model follow..  20  24....AAALAEEIGDRLKQARLNRDLTQSEVAEIAGIARKTVLNAEKGKVQLDIMIAILMALDLTEQIDLFI........... 90
44 -25.7003omt_A mol:protein length:73 uncharacterized protein  ali model follow..  19  7.........RKIFNRLKSVLAEKGKTNLWLTETLDKNKTTVSKWCTNDVQPSLETLFDIAEALNVDVRELIVSTKR...... 73
45 -25.5003bs3_A mol:protein length:76 Putative DNA-binding protein  ali model follow..  20  8........QQMMLNRIKVVLAEKQRTNRWLAEQMGKSENTISRWCSNKSQPSLDMLVKVAELLNVDPRQLIN.......... 71
46 -25.4004o8b_A mol:protein length:122 Uncharacterized protein  ali model follow..  19  1..........MLGTRLKAARIRAGYSQKQLGMLVGMDSARMNQYERERHSPNMRTSEQLAMVLQVPMAYLY........... 65
47 -25.3001dw9_A mol:protein length:156 CYANATE LYASE  ali model follow..  12  3QSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARLVGAKLDLDEDSILL.......... 74
48 -25.1003mlf_A mol:protein length:111 transcriptional regulator  ali model follow..  23  15........QSNAMKTLKELRTDYGLTQKELGDLFKVSSRTIQNMEKDSTNIKDSLLSKYMSAFNVKYDDIF........... 77
49 -24.7002l49_A mol:protein length:99 C protein  ali model follow..  12  1.......MSNTISEKIVLMRKSEYLSRQQLADLTGVPYGTLSYYESGRSTPPTDVMMNILQTPQFTKYTLW........... 64
50 -24.5003rzz_A mol:protein length:446 Hydroxyethylphoshphonate Dioxygenase (PhpD)  ali model follow..  8  4........MRIDPFKLAHWMNARKYTAAQTADLAGLPLDDLRRLLGDEAEPDPAAATALAEALSVEPSQLAADAHRN..... 73
51 -24.3002kpj_A mol:protein length:94 SOS-response transcriptional repressor, LexA  ali model follow..  7  2...VKDKQKAIFSENLNSYIAKSEKTQLEIAKSIGVSPQTFNTWCKGIAIPRMGKVQALADYFNINKSDLIEDKKLNIDTVP 80
52 -23.9005jub_A mol:protein length:310 Transcriptional regulator  ali model follow..  21  2......NLKDSIGLRIKTERERQQMSREVLCLGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDE. 77
53 -23.9001per_L mol:protein length:69 PROTEIN (434 REPRESSOR)  ali model follow..  20  1..........SISSRVKSKRIQLGLNQAELAQKVGTTQQSIEQLENG-KTKRPRFLPELASALGVSVDWLLNGTSDSNVR.. 69
54 -23.9003op9_A mol:protein length:114 Pli0006 protein  ali model follow..  10  6.......IQHQFAENLSRLKKEHGLKNHQIAELLNVQTRTVAYYMSGETKPDIEKLIRLATYFHLSIDELVGYVQEDKVWND 80
55 -23.8001zug_A mol:protein length:71 PHAGE 434 CRO PROTEIN  ali model follow..  26  1........MQTLSERLKKRRIALKMTQTELATKAGVKQQSIQLIEAG-VTKRPRFLFEIAMALNCDPVWLQY.......... 63
56 -23.6002qfc_A mol:protein length:293 PlcR protein  ali model follow..  27  3........AEKLGSEIKKIRVLRGLTQKQLSENI-CHQSEVSRIESGAVYPSMDILQGIAAKLQIPIIHFYEVLIYSDIER. 74
57 -23.6002p5t_A mol:protein length:158 Putative transcriptional regulator PezA  ali model follow..  19  1..........MIGKNIKSLRKTHDLTQLEFARIVGISRNSLSRYENGTSSVSTELIDIICQKFNVSYVDIVGEDKMLNPVED 72
58 -23.5001sq8_A mol:protein length:64 dh434  ali model follow..  21  2..........LMGERIRARRIQLGLNQAELAQKVGVDQQAIEQLENG-KAKRPRFLPELARALGVAVDWLLN.......... 62
59 -23.4005fd4_A mol:protein length:324 ComR  ali model follow..  18  12GSHMEVWFMKEFGQRVRQLRESASMTREQFCDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPER.. 94
60 -23.1005j2y_A mol:protein length:80 Regulatory protein  ali model follow..  15  2.ASHERTQPQNMAFRAKATRTARRESQETFWSRFGISQSCGSRFENGENLPPIYLLLHFYIEGQITDRQLAD.......... 73
61 -23.1002r63_A mol:protein length:63 REPRESSOR PROTEIN FROM BACTERIOPHAGE 434  ali model follow..  22  2...........ISSRVKSKMIQLGLNQAELAQKVGTTQQSIEQLENG-KTKRPRFLPELASALGVSVDWLL........... 60
62 -23.1005a7l_A mol:protein length:80 CI  ali model follow..  21  1.......MQTDTSNRLKQIMAERNLKQVDILNLSKLSKSTLSQYVNSVQSPDQNRIYLLAKTLGVSEAWLM........... 73
63 -22.7002jvl_A mol:protein length:107 TrMBF1  ali model follow..  19  29.....KTVGKEVGKAIEQGRQEPTMTQAELGKEIGETAATVASYERGTATPDQNILSKMERVLNVKLRGANIGAPRLGPKKK 107
64 -22.7004yv6_A mol:protein length:284 Transcriptional regulator  ali model follow..  17  1.......MDKELGKTLRRLRQGKQVSISSLADEH-LSKSQISRFERGESEISCSRLLNLLDKLNITIDEFVSTHSKTHTHFF 74
65 -22.6002aw6_A mol:protein length:317 PrgX  ali model follow..  20  1........MFKIGSVLKQIRQELNYHQIDLYSGI-MSKSVYIKVEADSRPISVEELSKFSERLGVNFFEILNRAGMNTKSV. 72
66 -22.1003zhi_A mol:protein length:83 CI  ali model follow..  22  3........KTDTSNRLKQIMAERNLKQVDILNLSKLSKSTLSAYVASVQSPDQNRIYLLAKTLGVSEAWLM........... 74
67 -21.9003zhm_A mol:protein length:79 CI  ali model follow..  22  1........KTDTSNRLKQIMAERNLKQVDILNLSKLSKSTLSQYVNSVQSPDQNRIYLLAKTLGVSEAWLM........... 72
68 -21.6004ryk_A mol:protein length:306 Lmo0325 protein  ali model follow..  26  1........MGSYGELIREIRLSKGLTQKEVYTGI-ISRSYAIGFEKGKHEITLSLFEEILKRIMVPLDEFFFIYRDFSSTE. 72
69 -21.0005u55_A mol:protein length:190 (S)-2-hydroxypropylphosphonic acid epoxidase  ali model follow..  10  2..............DVRTLAV-GKAHLEALLATRKMTLEHLQDVRHDATQDGLEHLQNVAQYLAIPLSEFFVGQTQSDLDDG 71
70 -21.0004yba_A mol:protein length:99 Regulatory protein C  ali model follow..  21  2...IQNHIKNMTPEICKASRALVNLTQKELALMAGIATPTIADFERGARKPHGNNLRSIIIAFENKGLDFVE.......... 70
71 -20.9005v5t_A mol:protein length:306 Conserved domain protein  ali model follow..  16  8.........RPLGEEIERIRKGKNIPLRVFD-ENGVSSRSYQRFVQGNSELRISDLAIIVEILSISPMEMTEKLTPMSKTVL 79
72 -19.7005y69_A mol:protein length:151 chain A  ali model follow..  10  2.........SMTIKLLDEFLKKHDLTRYQLSKLTGISQNTLKDQNEKPNKYTVSILRSLSMISGLSVSDVLFELEDIEKNSD 75
73 -18.9002a6c_A mol:protein length:83 Helix-turn-helix motif  ali model follow..  15  6....IMKMRSQLLIVLQEHLRNSGLTQFKAAELLGVTQPRVSDLMRGKDLFSLESLIDMITSIGLKVE.............. 70
74 -18.9003bdn_A mol:protein length:236 Lambda Repressor  ali model follow..  19  8.TQEQLEDARRLKAIYEKKKNELGLSQESVADKMGMGQSGVGALFNGINALNAYNAALLAKILKVSVEEFSPSIAREIYEMY 88
75 -17.7003tyr_A mol:protein length:88 Transcriptional regulator  ali model follow..  16  21.............NKLWKLLIDRDMKKGELREAVGVSKSTFAKLGKNE-NVSLTVLLAICEYLNCDFGDIIEALPE...... 82
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.