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Query: 4lt5_A mol:protein length:327 Naegleria Tet-like dioxygenase, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTTFKQQTIKEKETKRKYCIKGTTANLTQTHPNGPVCVNRGEEVANTTTLLDSGGGINKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDGSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNNCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLELTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPYYEDTQKNSLKIHKETKLast
1 -126.0004lt5_A mol:protein length:327 Naegleria Tet-like dioxygenase  ali model  100  1MTTFKQQTIKEKETKRKYCIKGTTANLTQTHPNGPVCVNRGEEVANTTTLLDSGGGINKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDGSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNNCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLELTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPYYEDTQKNSLKIHKETK 321
2 -36.5006ax6_A mol:protein length:235 Procollagen lysyl hydroxylase and glycosyltransferase  ali model follow..  15  1MGSSASGLVPRGSVPTEV---------------------------TLYDLPTRKEEWEKKYLHPEFLSHLQNFKDFDYTEICNDV-------------------------YSFPLFTPAFCKEVIEVMDKANLWSKGGDSYFD--PRIGGVESYPTQDTQLYEVGLDKQWHYVVFNYVAPFVRHLYNNYKTKDINLA-----------------VVKYDMERQSELAPHHDSSTYTLNIALNEYGKEYTAGGCEFIRHKIWQGQKVGYATIHAGKLLYHRALPITSGKRYILVSFVN........................ 229
3 -29.3003dkq_A mol:protein length:243 PKHD-type hydroxylase Sbal_3634  ali model follow..  12  2...............................................................................................GSDKIENLYFQGMLIEIPNVFSKQEVSHLREQLDARRWIDGNQTSGAMATTRKRNQQLDKDDPVAV--------------------------ALGQQIMDRLLAHPQFVSAALPLQFYPPLFNRYQGGETFGYHIDRTDLSATLFLSEPE-NYQGGELVIQDTYQSIKLSAGSLVLYPSSSL-HQVTPVLSGERTAAFMWLQSMVRD................... 193
4 -28.4005iqs_A mol:protein length:315 WelO5  ali model follow..  13  1.....................................MKSDYDIPTTENLYFQGSMSNNTVSTKPALHFLDINATEVKKYPTAIQD----------------INRSFDGMIIRGVFPRDTMEQVARCLEEGNDGGMKSILNKNEEFGTKVAQIYGHAIVGQSPDASSAIFRQACRTMFQGSPDFE-EQVESIFHSLSGLPVEIPTGPEGQTYTPATIRLLLEGREIAVHVGNDSDQLSYFIPLTVPE-AGGELVVYSLEVAYAPGPGDMLLFNGGRYYHRVSEVIGNSRRTIGGFL......................... 295
5 -23.0003w20_A mol:protein length:273 Putative uncharacterized protein  ali model follow..  10  2......................................................................QHTYPAQLMRFGTAARAEHMTIAAAIHAL----DADEADAIVMDIVPDGERDAWWDDEGFSSSPFTKNAHHAGIVATSVTLGQLQREQGDKLVSKAAEYFGIA-TRFVRLFSDALDAKPLTIGHDYEVEFLLATRRVYEPFEAPF---------NFAPHCDDVSYGLGGFLTIQGAD-NDAGMVMWDNRIMLKPQPGQLTLFQSKNL-HAIER-CTSTRRTMGLFL......................... 262
6 -21.8006fxk_A mol:protein length:718 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3  ali model follow..  13  543.............................................................................................................VYWFPLLSEQMCDELVAEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYE------------------DQWLQLLRTYVGPMTESLFPGYHTKARAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGLDYEGGGCRFLRYDVISSPRKGWALLHPGRL-YHEGLPTTWGTRYIMVSFVDPAA..................... 717
7 -20.6005c5t_A mol:protein length:228 Prolyl 4-hydroxylase  ali model follow..  9  19...............................................................................................ETSDRPGVCDGKYYEKIDGFLSDIECDVLINAAIKKGLIKSEVGGATENDPIKLDPKSRNSEQT--------------FMPGEHEVIDKIQKKTREFLNSKKHCIDKYNFEDVQV-------ARYKPGQYYYHHYDKDQRLATLMVYLKAPEEGGGETDFPTLKTKIKPKKGTSIFFWVKETLHAGLPVKSGEKIIANQWIRA....................... 220
8 -20.1004iw3_A mol:protein length:229 Putative uncharacterized protein  ali model follow..  12  33....................................................................................................LATHGWSQ---QAHFLPADLVRALAAECRRRDAEGE----------------LNPAGVGRGATQEVRETIRGDQIQWIDPGQAEACDQYLAAMDQLRLAINQGLFLGLEDFECHFALYP--PGAFYRRHLDRDRRMVSAVLYLNE-PHDGGQLRMFLADHDVEPVAGCLVVFLSGEVPHEVLPAGR-ERLSLTGWFRRR...................... 218
9 -19.6002g19_A mol:protein length:244 Egl nine homolog 1  ali model follow..  10  23....................................................................................................MNKHGICV---VDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYK--------------INGRTKAMVACYPGNGTGYVRHVDNDGRCVTCIYYLNK-AKVSGGILRIF-AQFADIEPDRLLFFWSDRRNHEVQP-AYATRYAITVWYFDADERARAKVKYLTGEKGVRVELN 236
10 -19.1004kbz_A mol:protein length:238 Egl nine homolog 1  ali model follow..  10  15..............................................................................................EYIVPCMNKHGICV---VDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYK--------------INGRTKAMVACYPGNGTGYVRHVDNDGRCVTCIYYLNK-AKVSGGILRIF-AQFADIEPDRLLFFWSDRRNHEVQP-AYATRYAITVWYFDADERARAKVKYLTGEKGLRVELN 234
11 -19.0002hbt_A mol:protein length:247 Egl nine homolog 1  ali model follow..  9  1....................................................................................MALPALKLALEYIVPCMNKHGICV---VDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYK--------------INGRTKAMVACYPGNGTGYVRHVDGDGRCVTCIYYLNK-AKVSGGILRIF-AQFADIEPDRLLFFWSDRRNHEVQP-AYATRYAITVWYFDADERARAKVKYLTGEKGVRVELN 230
12 -19.0005v1b_A mol:protein length:240 Egl nine homolog 2  ali model follow..  10  3................................................................................SEEALPSAPERLALDYIVPCMRYYGICV---VDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYK--------------INGRTKAMVACYPGNGLGYVRHVDNDGRCITCIYYLNQ-VKVHGGLLQIF-PVVANIEPDRLLIFWSDRRNHEVKP-AYATRYAITVWYFDADERARAKDKYQLASGQKGVQVP 236
13 -18.5005iax_A mol:protein length:226 Procollagen-Proline Dioxygenase  ali model follow..  13  29...............................................................................................REIQIISKFEEPLIVVLGNVLSDEECDELIELSKSKLARSK-------VGSSRDVNDIRTSSGAFLDDNELTAKIEKRISSIMNVPASHGEG---------------------------LHILNYEVDQQYKAHYDANNRISTLVMYLNDVE-EGGETFFPKLNLSVHPRKGMAVYFEYELTLHGGAPVTKGEKWIATQWVRRG...................... 214
14 -18.5002y33_A mol:protein length:252 EGL NINE HOMOLOG 1  ali model follow..  10  28....................................................................................................MNKHGICV---VDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYK--------------INGRTKAMVACYPGNGTGYVRHVDNDGRCVTCIYYLNK-AKVSGGILREGKAQFADIEPDRLLFFWSDRRNHEVQPAYA-TRYAITVWYFDADERARAKVKYLTGEKGVRVELN 241
15 -18.3005l9v_A mol:protein length:252 Egl nine homolog 1  ali model follow..  10  28....................................................................................................MNKHGICV---VDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLICHCNGKLGSYK--------------INGRTKAMVACYPGNGTGYVRHVDNDGRCVTCIYYLNK-AKVSGGILRIF-AQFADIEPDRLLFFWSDRRNHEVQP-AYATRYAITVWYFDADERAAAKVKYLTGEKGVRVELN 241
16 -18.1005lbc_A mol:protein length:252 Egl nine homolog 1  ali model follow..  10  28....................................................................................................MNKHGICV---VDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLVLHCNGKLGSYK--------------VNGRTKAMVACYPGNGTGYVRHVDNDGRCVTCIYYLNK-AKVSGGILRIF-AQFADIEPDRLLFFWSRRNPHEVQP-AYATRYAITVWYFDADERARAKVKYLTGEKGVRVELN 241
17 -17.8006ey1_A mol:protein length:257 HIF prolyl hydroxylase  ali model follow..  11  3.....................SSSSGLVPRGSHMDERRPKIGCDKTGLALEKTWQLQKNERLSNMVVNQ-------------------------------LNTNGFCI---INNFLGSSCSTEVLQQVLNLYQSGVFSNGQLA--RNVSVNRIRGDKIAWIGGDERGCEAIKYLSSCVDSLISRCNGRLGNYM--------------ITGRTKCMVACYPGSGLGYIRHIDNDGRCVTVLYYLNP-SQDCGGQLWNNENKVVKIDPDRLLLFWSDRNPHEVKP-AYAMRYAITLWYFDE...................... 240
18 -16.9004nao_A mol:protein length:326 Putative oxygenase  ali model follow..  8  1.................................................................MRGSGSMTSQHQEHTGTKRFSIQS---DPVEIHRAIVEDGVAI---IEGFLTPEQVQKLNKDVDAPLKADREQLKFKADKKDDPHFWLADFIPDHVARVHNLVDFSHCFRHEILN--HELLHKICRLTFEESGDYWLGYGAVIENGP----------TTEQKWHRDQPEGMLNFFTALTDFDAETGKTQYDHPIEYVGLKPGDTTIVSGKIT-HRGSD-SDKMRRAMIMIIPSILTPFDATCHLSRELVETMTPL. 266
19 -16.8002jij_A mol:protein length:233 PROLYL-4 HYDROXYLASE  ali model follow..  12  12...............................................................................................WRGEVVHLSWSPRAFLLKNFLSDEECDYIVEKAR----------------PKMVKSSVVDNESGKSVDSEIRTSTGTWFAKGEDSVISKIEKRVAQVTMIPLENHEG------------LQVLHYHDGQKYEPHYDGGQRVVTMLMYLTTVE-EGGETVLPNAGLAVKPIKGDALMFYSPASLHGSCPTLKGDKWSATKWIHVA...................... 221
20 -16.8005ybm_A mol:protein length:314 PrhA  ali model follow..  9  1..................................................................MGSSSSGLVPRGSHMPPRLQRFPATASADEIFAAFQEDGCVV---IEGFISPEQVARFSQEVDPAMEKIPVEVTNNGNSNDRTKRFSKCVIASPTFRNEIIE--SDLMHELCDRVFSKPGEGMGYHFNDNMVIEVQ--------------------APAQRLHRDQEECVINFFCAVTPFTEENGATRLKIETVPAIMQPGDCYLMSGKVI-HGAGH-TTDRRRALLAIIRRELRPMQAFSLSVPMKLAREMSER 269
21 -16.4005ybl_A mol:protein length:314 Multifunctional dioxygenase ausE  ali model follow..  9  1..................................................................MGSSSSGLVPRGSHMPSRLQKFPATAPADEIYAAFKEDGCVI---IEGFVPPDQMARFSQEIQPAMEKIQVQVTNDGNSNDRVKRFSKLVTTSPTFRHEILE--NDLMHELLQRVFSKPGEGMGYHFNDTMVIEVQ--------------------APAQRLHRDQEECLVNFFCAVTPFTVENGATRLKIDSVPAIMQPGDCYMMSGKVI-HGAGH-LSDQRRALASTIRRELRPVQAFPLWIPMQIATELSPR 269
22 -16.0003nnf_A mol:protein length:344 CurA  ali model follow..  8  2.......................................................................SSGVDLGTENLYFQSNAMNREQVEQLKQEYEEKGYCQ---IKKIFDFSAIKTIQKTLDQAKQESQISKEKVTLKLGGIDDIDTNDHAYDLVKYDFVSSFIQEKLALLNYITGKNLMIMHNALFSVEPN-----------------------HKGLPWHVGVEDFGASIWIPLDKITKERGGMQYVSTKEEDEYNLGDAFFFNKYVL-HQSVPLKPGLRRAFVILVDYDT..................... 271
23 -16.0004qkb_A mol:protein length:200 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial  ali model follow..  11  18............................................................................................................AVVRPGFLSTAEEETLSRELEPELRRRRYEYDH-------------WDAAIHGFRETEKSRWSEASMAIMRRVQAAAFGPGQTLLSSVHVLDLE-------------------ARGYIKPHVDSIKFCGATIAGLS-----LSPSVMPGEWLELLLEPGSLYILRGSAFSHEILRIPRGRRISVIC........................... 187
24 -15.9004y5s_A mol:protein length:315 Verruculogen synthase  ali model follow..  13  2..........................................................................PEFTVDSKPQLQRLAADADVDRMCRLLEEDGAFI---LKGLLPFDVVESFNRELDVQMAIPPPKGERLLADKYPPHFKYVPNVATTCPTFRNTVLINPVIHAICEAYFQRTGDYWLSAAFLREIE-----------------------MPAQPFHRDDAPVSLSVIFPLTEFTEENGATEVRDQAVLATMDPGDVLIVRQRVV-HANRTTAGKPRRVVLYFNSVQLTPFETYRTMPREMVESMTVL. 253
25 -15.9004nj4_A mol:protein length:250 RNA demethylase ALKBH5  ali model follow..  8  1..................................................................MSSGVDLGTENLYFQSMPERSDYEEQQLQKEEEARKVKS---GIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVIND----YQPGGCIVSHVDPIHIFERPIVSVS----SDSALCFGC-VLSLPVRRGSVTVLSGYAITHCIRP-IKERRAVIIL........................... 234
26 -15.4005zm2_A mol:protein length:306 Dioxygenase andA  ali model follow..  10  2....................................................................GSSSSGLVPRGSHMPPIRRVNASQGSDAAYQILQEDGCVI---VEQVICPNIIAKISDDVNRVMDKATIGA------KKGEQTHIINMHNRTIHMGDLVLTSKTYRDELLNL--PFAHEVLEKVFKKDSGDYWLNMGNILNMLP----------AEAQRPHRDDYDLMINITFPLNEFRHDNGGTLLAEDLPAAEMQVGDALIFTGK-CVHGGGA-SDKPRIGLLAAQPGYLTPRESNVNVPRDIVETMTPL. 263
27 -15.0004npl_A mol:protein length:250 RNA demethylase ALKBH5  ali model follow..  10  1............................................................................................DESEYEERRDAEARRVKIKQASIFTLEECARIEAKIDEVVAKADKGLYREHTVDRAPLRNKYFFGEGYTYGAQLEKRGPGQERLYSKGEVDDIPDWVHELVIDRLVTHGVIPEGFVNSAVIND----YQPGGCIVSHVDPIHIFERPIVSVS----SDSALCFGC-VLHLPVRRGSVTVLSGYAITHCIRP-IKERRAVIIL........................... 213
28 -14.8005m0t_A mol:protein length:294 Alpha-ketoglutarate-dependent non-heme iron oxygenase EasH  ali model follow..  11  6..............................................................................ETSKPTLRRIPRSAGDEAIFQVLQEDGVVV---IEGFMSADQVRRFNGEIDPHMKQWELGQ------KSYQESYLAGMRQLSSLPLFSKLFRDELMND------ELLHGLCKRLFGPESGDYWLTTSSVLETEP----------YHGQELHREHDESMLNFLTALTDFTAENGATRVADTAIPAVMNPGDAVLFTGK-TLHGAGK-TDFLRRGFPLIMQSCQFTPVEASVALPRELVETMTPL 254
29 -14.8004xaa_A mol:protein length:223 Putative oxygenase  ali model follow..  14  9..............................................................................................AAAIERFRRDGFANA---GPVLAPDAIARLKAGAERLITRFTDEG------LRSDDYWNFPVEGDERPVLYRVHNLEKQDWAPERDLLH--REELAQLAAAFVDGPVVPTAY-------ALVLKEPYRAAEVPWHRDRVRTVCNLSICLDDAGPHNGCLEATGPVVPVPVSQGDVVVHDVRLV-HGSGP-NGSWRRTIVIYADPAA..................... 219
30 -14.7003pl0_A mol:protein length:254 Uncharacterized protein  ali model follow..  14  38...................................................................................................................MPLDAFDMMLPYWEELAPDLHLKDGGHYRYRRHGCFMQTLQPGQLETVQHRAHWQPTTYNALHGGMERWFLPSWSALLVALGELFAKLRAPQGGRWYIEAHPFRIDTEGGVGAHRDGVD--FVAVVFIGRQGVRGGETRVFDAARFTLEQPWTVLLLDDQQVIHESTPLLPAHRDTLVLTYRSG...................... 248
31 -14.6002opw_A mol:protein length:291 PHYHD1 protein  ali model follow..  10  6..............................................................................................PSQLQKFQQDGFLV---LEGFLSAEECVAMQQRIGEIVAEMDVPLHCRTEFSEEQLRAQGSTDYFLSSGDKIRFFFEKGVFDEKGNFLVPPEKSINKIGFKVQTLARSLGLQMPVVVQSMYIFKQPHFGGEVSPHQDASGRVLGVWIAVEDATLENGCLWFNSLFVPTPVQRGALVLIHGEVV-HKSKQ-SDRSRQAYTFLMEASGTTWSPEN.............. 276
32 -14.5005ep9_A mol:protein length:305 SnoN,Epimerase SnoN  ali model follow..  12  1.................................................................MARSADQETEPGVPADLPAESDPAAL---ERLAARYRRDGYVH---VPGVLDAGEVAEYLAEARRLLAHEESVRWGSG----AGTVMDYVADAQLGSDTMRRLATHPRIAALAEYLAGSPLRLFKLEVLLKENK-------------------EKDASVPTAPHHDTAGTALTAWVALVDVPVERGCMTF---RVTVPLRAGDCTFHHARTV-HSAGA-TDEPRLSTAVYMDATA..................... 241
33 -14.4004o61_A mol:protein length:222 RNA demethylase ALKBH5  ali model follow..  10  17.............................................................................................................IRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVIND----YQPGGCIVSHVDPIHIFERPIVSVS----SDSALCFGC-VLSLPVRRGSVTVLSGYAITHCIRP-IKERRAVIIL........................... 210
34 -14.4002rdn_A mol:protein length:288 1-deoxypentalenic acid 11-beta hydroxylase; Fe(II)/alpha-ketoglutarate dependent hydroxylase  ali model follow..  13  2...........................................................................SHMTNVTGDYTDCTPLLGDRAALDFYEEHGYLF---LRNVLDRDLVKTVAEQMREGLVALGAADPHATLEELTIDSFESVDEVAMHDYVKYDAFWNPSTIKVFEQVFG--------------EPVFVFLSTTIRYYPSQAGSEEPSFHYLTPFHQDGNQDFRTFWIPLIRTTRESGGVALAD--LHSPMEPGDILLFHAHMC-HKSIPNLSKDRMSMTRVQPAKS..................... 255
35 -14.4005y7t_B mol:protein length:315 Iron/alpha-ketoglutarate-dependent dioxygenase asqJ  ali model follow..  9  1.........................................................................MMTSKDHVKSQIPRLSAINDLHKIWPTVEEHGAAI---IESFLSLDIVRRLNEEVDPFVKIEP---------IPAAKTKDHPNHVLSTTTRLVNVLAPISKAYREDVLNSKVLHRICSDAFHVYGDYWVLMGAVMELAP----------NPAQPLHRDMRATSINFLVALSPFTAENGATHVMDATVRALMNPGDALLITDS-TIHCGGA-GTETRRLLITMGISQLTPLESNLAVPRPVIESLTPL. 256
36 -13.8002a1x_A mol:protein length:308 Phytanoyl-CoA dioxygenase  ali model follow..  14  1..............................................................SGTISSASFHPQQFQYTLDNNVLTLEQRK--------FYEENGFLV---IKNLVPDADIQRFRNEFEKICRKEVKPLGLTVMRDVT-----ISKSEYAPSEKMITKVQDFQEDKELFRYCT--LPEILKYVECFTGPNIMAMHTM-------LINKPPDSGKKTSRHPLHQDLHYCAWTAMEHISRNNGCLVVNKARVHLVMEKGDTVFFHPLLI-HGSGQ-TQGFRKAISHFASADC..................... 257
37 -13.8003mgu_A mol:protein length:644 PKHD-type hydroxylase TPA1  ali model follow..  10  3...............................................RKTAEVKGEKERNSKQISLEEDKIKGMFNPKIWDKTFQDGLKKEIEDSQPYNWG---------TIHELVNDDLLRAVRKEIETEIHFTKKET---DIYRVNQSGDLANLSGLDWDDLSRLPNLFKLRQILYSKQYRDFFGYVTKA-------------GKLSGSKTDMSINTYTKGCHLLTHDDSRRISFILYLPDPDRKWKGGGLRLPHSDPSAKLVPNQIAFFKPGFSFHDVEEVKVDKRLSIQGWYHIPQVGEEGYIPGEEEAWVRNNTST 270
38 -13.6003bvc_A mol:protein length:212 Uncharacterized protein Ism_01780  ali model follow..  13  10..........................................................................................................LYHAPLSDHGPAIDAEEMESSCYAIAEDDEAGQGWCEENGYPGYTSYASLTDLPWRFPI------------FADLVKSLDAHVAAFAEDLEFDLDGRALELEDLWIN-----ILPEGGSHASHIHPHSV-ISGTTYV-SMPGGTSALKLED-FIYVTPAVGDVLLWES--LRHEVPM-SEDDRISVSF........................... 199
39 -13.2004xab_A mol:protein length:252 EvdO2  ali model follow..  9  12..............................................................................................HRDREEFRSRGFAI---LPQVASESEVAWLRQAYDRLFVRRATPG------AEDFYDIAGQRDREGPPLLPQIIKPEKYVPELLDSPHFARCRSIASAFLDMAEEELEFYGHAILKPP--------RYGAPTPWHQDEARRGLSIWTTLDEATVESGCLHYPTSAVACPLAPGGAVVHDFRTP-HYAGP-TDQPRRAYVLFMSAPA..................... 238
40 -13.2004xbz_A mol:protein length:334 EvdO1  ali model follow..  9  5...................................................SSGLVPRGSHMMSSVGDLRVVNRIAECDIRRTGLLPEHVT---------FRRQGVLV---VRGLLTPQELADVQEAGRALIDRAWSTRSMEDTVWTLEPDQPGAAPVRIEYVVDKARPIAMLAG----------HPLLLRIMEQLVGPNLIPTWD-------SMVFKTPAGAPRLAWHRDGAGRVIDAGIYLDPAPEDNCVWCIPESNVPAVMQPGDLLLHNILTL-HGAPAVVGKQRRVIYFYRPAEV..................... 260
41 -13.0004nhk_A mol:protein length:647 PKHD-type hydroxylase TPA1  ali model follow..  10  1...........................................MSSGVDLGTENLYFQSMLEEDKIKGMFNPKIWDK-----TFQDGLKKEIEDSQPYNWG---------TIHELVNDDLLRAVRKEIETEIHFTKKETDIYRVNQSGDLANLSGLDWDDLSRLPNLFKLRQILY----------SKQYRDFFGYVTKAGK------LSGSKTDMSINTYTKGCHLLTHDDSRRISFILYLPDPDRKWKGGGLRLPHSDPSAKLVPNQIAFFKPGFSFHDVEEVKVDKRLSIQGWYHIP...................... 245
42 -13.0002rg4_A mol:protein length:216 Uncharacterized protein  ali model follow..  13  14..........................................................................................................LYHAPLSEHGPALDPAEFAASCYSIAEDDDAGQEWCEREGYPGYTSYASLTDLPWRFPI------------FADLVKSLDAHVAAFAEDLEFELDGKALRLEDIWIN-----ILPEGGVHGSHIHPHSV-ISGTTYVAMPE-GTSALKLED-FRSVAPKVGDVLLWES--LRHEVPM-AEEDRISVSF........................... 203
43 -12.9003kt1_A mol:protein length:633 PKHD-type hydroxylase TPA1  ali model follow..  11  37.............................................................................................................GTIHELVNDDLLRAVRKEIETEIHFTKKETDIYRVNQSGDLANLSGLDWDDLSRLPNLFKLRQILY----------SKQYRDFFGYVTKAGK------LSGSKTDMSINTYTKGCHLLTHDDSRRISFILYLPDPDRKWKGGGLRLPHSDPSAKLVPNQIAFFKPGFSFHDVEEVKVDKRLSIQGWYHIP...................... 229
44 -12.5004mhr_A mol:protein length:314 Ectoine hydroxylase  ali model follow..  11  37..............................................................................................ARQAAAFDRDGYIV---LEDIFSADEVAFLQKAAGNLLADPAALDADTIVTEPQSNEIRSIFEIHAQSPVMARLAADARLADVARFLLGDEVYIHQSRLNYKPGFK----------------------GREFYWHSDFEMRALSMSVLLAENTPHNGPLMV----VAPTGKPGTVILFDCNLM-HGSNGITPFPRANAFLYNAVSN..................... 270
45 -12.5004xcb_A mol:protein length:261 oxidase/hydroxylase  ali model follow..  13  9..............................................................................................REQLYIFDTTGFLV---IPGVFGSGEVESFRSELERLDTV--------------------DPGFPRTRRYPDLPAASPVFARLADRLLAPVRDVVNQPLRLLEGYGLRRTKD--SVLYLHGGNSELLDLGDRQVGRDLSIT-VKALVYLSD-PEDGSFCYVQGSHSDVFVRSGDVLLLNEA-LMHGTRR-TEGDRLLTAFYGPTFFTEWRELDAETADLRGAGYVDH 253
46 -12.4003emr_A mol:protein length:310 EctD  ali model follow..  11  8.........................................................RQNNQPKILKRKDPVIYTDRSKDNQAPITKEQLD--------SYEKNGFLQ---IKNFFSEDEVIDMQKAIFELQDSIKDVASDKVIREPESNDIRSIFHVHQDDNYFQDVANDKRILDIVRHLLGSDVYVHQSRINYKPGFK----------------------GKEFDWHSDFEMRAISVSIALSDNYSFNGPLML----SVPTGKAGSVTLFESNTM-HGSTSITPYPRNNLFMYNSVKN..................... 271
47 -12.3005epa_A mol:protein length:279 SnoK  ali model follow..  13  20..............................................................................................KEAVRFYREQGYVH---IPRVLSETEVTAFRAACEEVLEKEGREIWGAG---EDEVQVHYVAQAWQKHPELRSLVLHPEISGIALRLAGAPLRVYSSDILVKEPKR----------------------TLPTLVHDDETSATLTAWIALTDVPVERGCMSYWQPRVAVPVRAGDVVFHHCRTV-HMAEA-SDSVRMAHGVYMDADATYRPGVQDGHLSRLSPGDPLE 259
48 -12.2005nch_A mol:protein length:268 Leucine hydroxylase  ali model follow..  12  8..............................................................................................ADQVEKYKSDGYVL---LEGAFSPEEVHVMRQALKKDQ-------------EVQGPHRILEEDGRTVRALYASHTRQSVFDQLSRS-------------DRLLGPATQLLECDLYIHQFKINTKRAFGGDSWAWHQDPAPRAVNVGVFLSDVTEFNGPVVF----VSPKAASGSVMLFHPEII-HGSAPISPFARDLLIITYNDVANAPKPAGEPRPEYVIGRDTT. 255
49 -11.8003khb_A mol:protein length:219 Alpha-ketoglutarate-dependent dioxygenase alkB  ali model follow..  9  7..........................................................................................LFADAEPWQEPLAAG---AVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAP----------------GAKLSLHQDKDEPDLRVSVSLGL-IFQFGGLKRNDPLKRLLLEHGDVVVWGGRLFYHGIQPLKADCRYNLTF........................... 212
50 -11.8003thp_A mol:protein length:345 Alkylated DNA repair protein alkB homolog 8  ali model follow..  7  113............................................................................................................LMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVKHFGYEFHYENNNVDK------DKPLSGGLPDICESFLEKWLR-------------KGYIKHKPDQMTINQYEPGQGIPAHIDTHSAFEDEIVSLS-----GSEIVMDGIAVPVMLPRRSLLVMTGESWTHGITCSKRGLRTSFTF........................... 309
51 -11.6006alm_A mol:protein length:394 Alpha-ketoglutarate-dependent L-arginine hydroxylase  ali model follow..  8  1MGSSPRGSHMASMTGGQQMGRGSEFMTESPTTHHGAAPPDSVATPVRPW-LTPAEAAAAAALAARCAQRYDETDGPEFLLDAPVIAHERRLRTFMARARLDAWPHALVVRGNP--VDDAALGSTPVHWRTARTPGSRPL---------------------------------------SFLLMLYAGLLGDVFGWATQQDGRVVTDVLPIKGGEHTLVSSSSRQELGWHTEDAFSDYVGLLSLRNPDGVATTLLIDASLYELVLDQGDVAFIDNRRAVHGRRAFQGRDRWLKRINITRDLHRSRKAWAGDSRVLGQR.... 388
52 -11.6005j4g_A mol:protein length:107 Uncharacterized protein  ali model follow..  12  18............................................................................................................................................................................................................EVLNENSSHKEIRICMPKGAVMDKHKAPGAISVQVL---------EGKIVFEVGDEKIEMPKGALISLEAQ-VLHRLDALENSVIRLSLS........................... 97
53 -11.5002fd8_A mol:protein length:211 Alkylated DNA repair protein alkB  ali model follow..  12  9............................................................................................................AVILRRFAFNAAEQLIRDINDVASQSPRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYA---------PGAKLSLHQDKDEPDLRVSVSLGL-IFQFGGLKRNDPLKRLLLEHGDVVVWGGRLFYHGIQPLKADCRYNLTF........................... 199
54 -11.4003fjs_A mol:protein length:114 uncharacterized protein with RmlC-like cupin fold  ali model follow..  17  28............................................................................................................................................................................................................AALFKEHRLEVMRMVLPAGKQVGSHSVAGPSTIQCL---------EGEVEIGVDGAQRRLHQGDLLYLGAG-AAHDVNAITNT-SLLVTVVL......................... 108
55 -11.3001yhf_A mol:protein length:115 hypothetical protein SPy1581  ali model follow..  16  32............................................................................................................................................................................................................RTLVQRQDLGITVFSLDKGQEIGRHSSPGDAMVTIL---------SGLAEITIDQETYRVAEGQTIVMPAG-IPHALYAVEAFQMLLVVV........................... 111
56 -11.2005j4f_A mol:protein length:119 Uncharacterized protein  ali model follow..  13  32............................................................................................................................................................................................................EVLNENSSHKEIRICMPKGAVMDKHKAPGAISVQVL---------EGKIVFEVGDEKIEMPKGALISLEAQ-VLHRLDALENSV--IRLSLSKK....................... 113
57 -11.2002ozj_A mol:protein length:114 Cupin 2, conserved barrel  ali model follow..  16  30............................................................................................................................................................................................................MALAQSDRVQISLFSFADGESVSEEEYFGDTLYLIL---------QGEAVITFDDQKIDLVPEDVLMVPAH-KIHAIAGKGRFKMLQITLIDEER...................... 114
58 -11.0004nig_A mol:protein length:205 Alpha-ketoglutarate-dependent dioxygenase AlkB  ali model follow..  12  8............................................................................................................AVILRRFAFNAAEQLIRDINDVASQSPRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYA---------PGAKLCLHQDKIHPDLRVSVSLGL-IFQFGGLKRNDPLKRLLLEHGDVVVWGGRLFYHGIQPLKADCRYNLTF........................... 198
59 -10.9005xeg_A mol:protein length:231 Oxidoreductase, 2OG-Fe oxygenase family protein, putative, expressed  ali model follow..  16  13............................................................................................................MVLLKKFLKHDDQVDIIRRCQKLGIGSGGFYTPGYRDGGKLSLQMMCLGKNWDPNSRSYGDTRPFDGAQPPSIPEVFSKIVKDAIQASNERPANDVEELPPLSPDICLVNFYTSSGKLGLHQDKDETKPSVSFSLGD-EFLYGDVNDVDKASKVDLESGDVLIFGGRLIFHGVSRIKRPGRLNLTF........................... 228
60 -10.8006EC3 Entity 1(prereleased)  ali follow..  11  250..............................................................................................GAQIRRFREDGFVN---AGPVFADDTIARLKAGAIDLISRFTEHGHVSDDYWNYDVENEAPVLYRIHNLEKQDWAERELLF----------RPELAELAAAFVGSPVVPTAF-------ALVLKEPKRAAGVPWHRDRAHTVCNLSICLDTAGPENGCLEGGGPRVPVPSKVGDVIVHDVRLV-HGSGP-SDQWRRTIVIFANPAI..................... 458
61 -10.6004nhx_A mol:protein length:562 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1  ali model follow..  10  1MGSSSSGLVPRGSHMNGKRPAEPG--------------ARVGKKGKKEVMAEFSDAVTEETLKKQVAEAWSRRTPFSHEVIVMD----------MDPFLHC---------VIPNFIQSQFLEGLQKELMNLDFHEKYNDLY------KFQQSDDLKKRREPHISTLRKILFEDFRSWLSDISKI-------------------------ESTIDMSCAKYEFTDALLCHDDEEGRRIAFILYLVP-PWDGGTLDLYSIDIVKSLIPNKLVFFEVSPVSHQVSEVLSESRLSISGWFHGP...................... 254
62 -10.6002csg_A mol:protein length:424 putative cytoplasmic protein  ali model follow..  9  1.....................SNAMTTPFTHETLPADPKAAIRQMKQALRAQIGDVQAVFDRLSATIAARVAEINDLKAQGQPVWPIIPFS--SDATRAEVKRRGCAV---IKGHFPREQALAWDQSMLDYLDKNHFDEVY----KGPGDNFFGTLSASRPEIYPVYWSQAQMQARQSEEMALAQSFLNRLWQVEHDGKRWFNPDISIIYPDRIRRRPPGTTSKGLGAHTDSGARTFQGWTALSDMLPGQGLLVVPIPESIPPLEAGDSVWWHCD-VIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYARKVKAALETGAS 390
63 -10.6002fct_A mol:protein length:313 syringomycin biosynthesis enzyme 2  ali model follow..  8  12..............................................................................................AEQRASFEKNGFIGP---FDAYSPEEMKETWKRTRLRLLDRS----------AAAYQDLDAISGGTNIANYDRHLDDDFLASHIPEICDRVESILGPNVLCWRTEFFPKYPG----------------DEGTDWHQADTGGTITVWTAFTDANIANGCLQFEASAVPMQMKAGQFIIFWSTLM-HASYP-SQEMRMGFASYVPSFV..................... 263
64 -10.6005fq0_A mol:protein length:114 KDGF  ali model follow..  13  31...................................................................................................................................................................................................................DLMAVCVKFDRGAVGTPHQHERHDQIGYVV--------QGAFEVELEGEKRRLSPGDAFVAPHH-TMHGAVALEPDSLVIDLF........................... 104
65 -10.6001e5r_A mol:protein length:290 PROLINE OXIDASE  ali model follow..  14  76.....................................................................................................................................................................................................PYLKEIVTTVFDGTHLQMARSRNLKNAIVIPHRDFVDRYFRTFMVL-----DSPLAFHSNEDTVIHMRPGEIWFLDAA-TVHSAVNFSEISRQSLC............................ 172
66 -10.5003l2h_A mol:protein length:162 Putative sugar phosphate isomerase  ali model follow..  18  57..............................................................................................................................................................................................................................KESTEYHLHHYEEEAVYVL--------SGKGTLTMENDQYPIAPGDFVGFPCHAAAHSISNDGTETLVCLVIGQRLD...................... 125
67 -10.4004m23_A mol:protein length:364 L-arginine beta-hydroxylase  ali model follow..  10  1MGS--------SSSGLVPRGSHMSNLTDQSTPSYSLTPAEASAVAELTLELAAAYGSFGDPVLLRDLPRLAARLPEGVQDFLREFKLA-------------DRHGHTVIRGHD----------------------------------------FDQRRIGPTPDHWRGRVRPGPEFPEELLLMLYSALLGEPFGWATQQDGHLVHDIFPIRSHENDQLGMGSKQLLTWHTEDA--DYLILGALRNPDHVPTTVVVDSGMREVVADQGDVLFIDNHRAVHGRLPFQGTDRWLKRVCVTSDLRRSREMRATSATRL....... 356
68 -10.2005fpx_A mol:protein length:113 PECTIN DEGRADATION PROTEIN  ali model follow..  14  32...................................................................................................................................................................................................................DLMMVCVHFDKGAIGVAHKHDIHDQIAYVA--------AGSFEVEIEGQKRILKAGDAYRAVKN-EMHGAVSLEDNSILIDTF........................... 105
69 -10.2001lr5_A mol:protein length:163 Auxin binding protein 1  ali model follow..  9  38.................................................................................................................................................................................................................MKEVEVWLQTISPGQRTPIHRHSCEEVFTVLKGKGTLLMGSSSLKYPGQPQEIPFFQNTTFSIPVND-PHQVWNSDEHEDLQVLVIISRPPAKIFLYDDWSMPHTAAVLKFP 148
70 -10.1001v70_A mol:protein length:105 probable antibiotics synthesis protein  ali model follow..  16  20............................................................................................................................................................................................................IPVFQSERMLYDLYALLPGQAQKVHVHEGSDKVYYAL--------EGEVVVRVGEEEALLAPGMAAFAPAG-APHGVRNESASPALLLVVTA......................... 102
71 -10.1003gja_A mol:protein length:319 CytC3  ali model follow..  11  14..............................................................................................PEEVARFERDGYIGP---VKIFEPEEMTRRWNIIRRQ--------------LDRSLAIYPDSNGKANISNYDRHLDIDLLAEHIPEIVDRVGSLIGRNLLCWRSEFFPKYQG----------------DEGTDWHQAATIGTITVWTAFTHSTEQNGCLQL----YPMVLKPGEAVIFWSNTM-HASLPHTGSKRMGFAAYVPTQV..................... 265
72 -10.0002pfw_A mol:protein length:116 Cupin 2, conserved barrel domain protein  ali model follow..  15  26............................................................................................................................................................................................................QMLGFNHELMAVKIWFDKGAEGYVHAHRHSQVSYVV---------EGEFHVNVDGVIKVLTAGDSFFVPPH-VDHGAVCPTGGILIDTFSPAREDFVEGLS................ 116
73 -9.9902dbi_A mol:protein length:461 Hypothetical protein ybiU  ali model follow..  8  24IPTTENLY--FQGSSGSSGMASTFTSDTLPAD-----HKAAIRQMKHALRAQLGDVQQIFNQLSDDIATRVAEINALKAQGDAVWPVLSYA--TAEQREQIKRRGCAV---IKGHFPREQALGWDQSMLDYLDRNRFDE------VYKGPGDNFFGTLSASRPEIYPIYWSQAQARQSEEMANAQSFLNRLWTFESDGKQWFNPDVSVIYPDRIRRRPPGTTSKGLGAHTDSGARTFQGWTALSDMLPGQGLLVVPIPESIPKLEAGDSVWWHCD-VIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYAHKVKAALEKGAS 427
74 -9.8703cjx_A mol:protein length:165 Protein of unknown function with a cupin-like fold  ali model follow..  13  48.........................................................................................................................................................................................................................ASFAPGLTLPLHFHTGTVHMYTI---GCWYYTEYP--------GQKQTAGCYLYEPGGSI-HQFNTPRDNEGQTEVIFMLSGCNVNFTQDGTYLGLSDAGVIKN 140
75 -9.8706daw_A mol:protein length:342 Non-heme iron hydroxylase  ali model follow..  9  4.......................................RGSHMMIRYVDLDAAEGAALDELTRSVLRDHGASSSPSLLDDLSLVAHRPRLIRELRRFRTAEEASCLVVRGLP--------------------------------RRLGPTPLDWREPPREPESEVHEVFLTLATAHLGDIFGWSTLQNGRLVHDVLPVPSHENDQSGHG------------TVELAWHTEDG--DYLLLLGLRNHDAVPTGVALQRNLTDVVLSPGDLLVIDNYRVVHGRAAFKGTDRWLKKAVVTRDLRKSRAHRKSAAERV....... 340
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A.; RIKEN GER Group; GSL Members. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res. 2003 Jun;13(6B):1376-88.