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Query: 4njg_A mol:protein length:230 7-carboxy-7-deazaguanine synthase, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGSSSSGLVPRGSHMTYAVKEIFYTLQGEGANAGRPAVFCRFAGCNLWSGREEDRAQAVCRFCDTDFVGTDGENGGKFKDADALVATIAGLWPAGEAHRFVVCTGGEPMLQLDQPLVDALHAAGFGIAIETNGSLPVLESIDWICVSPKADAPLVVTKGNELKVVIPQDNQRLADYAKLDFEYFLVQPMDGPSRDLNTKLAIDWCKRHPQWRLSMQTHKYLNIPLast
1 -92.3004njg_A mol:protein length:230 7-carboxy-7-deazaguanine synthase  ali model  100  1MGSSSSGLVPRGSHMTYAVKEIFYTLQGEGANAGRPAVFCRFAGCNLWSGREEDRAQAVCRFCDTDFVGTDGENGGKFKDADALVATIAGLWPAGEAHRFVVCTGGEPMLQLDQPLVDALHAAGFGIAIETNGSLPVLESIDWICVSPKADAPLVVTKGNELKVVIPQDNQRLADYAKLDFEYFLVQPMDGPSRDLNTKLAIDWCKRHPQWRLSMQTHKYLNIP 224
2 -60.5005tgs_A mol:protein length:263 7-carboxy-7-deazaguanine synthase  ali model follow..  27  1MGSSSSGLVPRGSHMGIPVLEIFGTIQGEGMVIGQKTMFVRTAGCDYSCSWCDSAFTWD----------GSAKKDIRWMTAEEIFAELKDI--GGDAFSHVTISGGNPALLKQLAFIELLKENNIRAALETQGTVYWFTLIDDLTISPKPPSSKMVTNFQKLDHRQHAVSLKVVIFNDEDLEFAKTVHKRYPGIPFYLQVGNDDVAELNLVRVLPQLHTLLW.. 251
3 -33.7003c8f_A mol:protein length:245 Pyruvate formate-lyase 1-activating enzyme  ali model follow..  15  10....................ESCGTVDGPGIRF-----ITFFQGCLMRCLYCHNRDTWDT-------------HGGKEVTVEDLMKEVVTYRHMNASGGGVTASGGEAILQAEFDWFRACKKEGIHTCLDTNGFVRLLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANKNVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVE-LLPYHEL.... 204
4 -23.4006djt_A mol:protein length:331 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase  ali model follow..  16  1MGSSSSGLVPRPEEIYKILRKQRYQIDGHTAVHRCIQCTPSVIWCQQNCIFCWRVLP------RDIGIDISQIKEPKWEEPEVVYEKILAFKEALEPKHVAISLSGEPTLYPYLELIKIFHKNGFTTFVVSNGILTEKIEPTQLYISLDAYDLDSYRRICG-YWESILNTLDILKEKKRTCIRTTLIRGYNDDILKFVELYERADVHFIELK............ 264
5 -23.0006b4c_A mol:protein length:298 Viperin  ali model follow..  14  1...........................GGRVRTGQVPVSVNYHKCNKECLFC------------------HTATTSHVEKPENAKRGLTLLKQA--GMKKINFAGGEPFLYPKFEMIDFCKETLESVSIVTNGSLKHGRNIDILAVSCDSFNEATNIKIGRGSGDNVQKLYEIGSWCQKY---LNTVVNKFNHLEDMNDHLNAL.................... 174
6 -22.9005vsl_A mol:protein length:318 Radical S-adenosyl methionine domain-containing protein 2  ali model follow..  13  2.........KEQPQVRGELEETQETQEDGNSTQRTTPVSVNYH-CNYKCGFC------------------HTAKTSFVLPLEEAKRGLLLLKQA--GLEKINFSGGEPFLQDRGEYLGKLVRF--SVSIVSNGSLDYGEYLDILAISCDSFDEQVNALIGRGQ-----------------------------GKKNHVENLQKLRRWCRDYKVAFKINSVI... 181
7 -22.5002yx0_A mol:protein length:342 radical sam enzyme  ali model follow..  13  78.........................................LAWCTHNCIFCGTELPQPWDDPAFIVEESIKAQRKLLIGYKGNPKVDKKKFEEAWNPTHAAISSGEPMLYPYMDLVEEFHKRGFTTFIVTNGTIPEDKLPTQLYVSITAPDIETYNSVNPDGWERILRFLELMRDLPTRTVVRLTLVKGENMHS--PEKYAKLILKARPMFVEAK........ 272
8 -21.1005v1q_A mol:protein length:459 Radical SAM  ali model follow..  11  103.................NARKHVAKLKKHNILSFPLELVIYPSYCDLKCGFCFL----------------ANREDRNAKPAKDWERILRQAKDN--GVLSVSILGGEPTRYFDINLLIACEELKIKTTITTNAQLIKKSTVEILVLSLQTLDSKLNFELMGVRPDRQIKLAKYFNEVGKKCRINAVYTKSYEQIIELVDFCIEN.................... 282
9 -20.3005wgg_A mol:protein length:453 Radical SAM domain protein  ali model follow..  14  100.....................................CLHISHDCNLRCKYC--------------ASTGNFGGQRNMMSLEVGKKAIDFLISESGNRKNLEIDGGEPMMNFDVGIIEYARQKNFRFTLTTNGLLLNDENIKYIN-ENMQNIVLSIDGRKEVN-----DRMRIRIDGSGCYDDILPKFKYVAESRNQDNYYVRGTFTRENMDFSNDVLHLA... 274
10 -19.7006c8v_A mol:protein length:394 Coenzyme PQQ synthesis protein E  ali model follow..  15  29.........................................THRCPLRCPYC--------------SNPLELDRRSAELDTQTWLRVLTEAAGL--GVLHVHLSGGEPTARPDIEITAKCAELGLYSNLITSGVGGALAKLDHVQLSVQGVDAANAEKIGGLKNAQPQKMQFAARVTELGLPLTLNSVIHRGNIHEVPGFIDLAVK.................. 186
11 -19.2003can_A mol:protein length:182 Pyruvate-formate lyase-activating enzyme  ali model follow..  16  1..............................................................................................SNAGGGVTFCGGEPLLHPEFDILKRCGQQGIHRAVDTTLLARVMRNCELLLIDLKSMDSTVHQTFCDVPNELILKNIRRVAEADFPYYIRIPLIEGVNADEKNIKLSAEFLASLEIINLLP-YHDI.... 137
12 -17.5004k36_A mol:protein length:392 Anaerobic sulfatase-maturating enzyme  ali model follow..  11  6....................................LLIKPASSCNLKCTYC------------HSLSDNRNVKSYGIMRDEVLESMVKRVLNEANGHCSFAFQGGEPTLEKLMELQRKHNYKNLKISLQTNGTLIDESWAKFLSMDGPKEIHNLNRKDCCGLDTFSKVERAAELFKKYKVEFNILCVVTSNTARHVNKVYKYFKE.................. 183
13 -17.1001tv7_A mol:protein length:340 Molybdenum cofactor biosynthesis protein A  ali model follow..  15  1..............MVEQIKDKL----------GRPIRDLRLS-CNFRCDYCMPK--------EVFGDDFVFLPKNELLTFDEMARIAKVYAEL--GVKKIRITGGEPLMRRDLVLIAKLNQID-DIGLTTNGLLLKKHGQKLVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGIND-DQIIPMLEYFKDKHIEIRFIEFM....... 197
14 -15.8004m7t_A mol:protein length:270 BtrN  ali model follow..  15  21....................................MIEVEVNSCNRTCWYCPNSVS--------------KRKETGEMDPALYKTLMEQLSSLDFAGRISFHFYGEPLLCKNLLFVGMTTEYIARPIIYTNGDF-TELGIQKFIVTQHAGAKHKFRGV................................................................. 141
15 -15.7004m7s_A mol:protein length:269 BtrN  ali model follow..  15  7....................................MIEVEVNSCNRTCWYCPNSVS--------------KRKETGEMDPALYKTLMEQLSSLDFAGRISFHFYGEPLLCKNLLFVGMTTEYIARPIIYTNGDF-TELGIQKFIVTQHAGAKHKFRGV................................................................. 127
16 -12.3002a5h_A mol:protein length:416 L-lysine 2,3-aminomutase  ali model follow..  9  80AIPTALELNKAAADLEDPLHE-DSPVPGLTHRYPDRVLLLITDMCSMYCRHCTRRRF---------------AGQSDDSMPMERIDKAIDYIRNTPQVRDVLLSGGDALLVSDETLEYIIAK---IVRIGSRTPVVLPQRITWLNTHFNHPNEITEE---------STRACQLLADAGVPLGNQSVLLRGVNDCVHVMKELVNKLVK................. 281
17 -11.9003rf9_A mol:protein length:404 Ribosomal RNA large subunit methyltransferase N  ali model follow..  11  96.....................AIAVGDQETVYIDRATLCVSSQGCALECKFCST----------------AQQGFNRNLRVSEIIGQVWRAAKIQRPITNVVMMGGEPLLNLNNVVMEIMLDDF-RVTLSTSGVVPALDKLG-LAISLHAPNDEIRDEIVPINKKYNIETFEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPKINLIP......... 310
18 -11.0005l7j_A mol:protein length:459 ELP3 family  ali model follow..  10  15....................................AVMTKPLPCPGKCIYCPTFAATPQSYTPESPAVLRAKSC-EYQAYKQVALRLRIIQDMGHPTDELIIMGGTFLSADITYQYGFIKDCYDALNGVVAGSLEEAKTINETAVGLCIETRPDICGKAEIQRMIDFGTTRVELGVQMLDDDIYKLVERGHRVSDVAEATCLL----REYGLKVHYHWMPGLP 203
19 -10.6002jz8_A mol:protein length:87 Uncharacterized protein BH09830  ali model follow..  7  1MADYNIPHFQNDLGYKIEIGVKEFMCVGATQPFDHPHIFIDMGS-EKICPYCSTLYRYDPSLSYNQTNPTGCLYNPK................................................................................................................................................... 79
20 -10.4005l7l_A mol:protein length:446 ELP3 family, ELP3 family  ali model follow..  10  15....................................AVMTKPLPCPGKCIYCPT-FAATPQSYTPESPAVLRAKSCEYQAYKQVALRLRIIQDMGHPTDELIIMGGTFLSADITYQYGFIKDCYDALNGVVAGSLEEAKTINETAVGLCIETRPDICGKAEIQRMIDFGTTRVELGVQMLDDDIYKLVERGHRVSDVAEATCLL----REYGLKVHYHWMPGLP 203
21 -10.2005xtb_T mol:protein length:95 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial  ali model follow..  12  37...ENFAIDLIAEQPVSEVETRVIACDGGGGALGHPKVYINLDTKTGTCGYCGLQFRQH..................................................................................................................................................................... 94
22 -10.1002jvm_A mol:protein length:80 Uncharacterized protein  ali model follow..  15  6KTRQESARMSIEAPETVVVSTWKVACDGGEGALGHPRVWLSIPH-FVECGYCDRRYIHE..................................................................................................................................................................... 66
23 -10.1005o31_R mol:protein length:96 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial  ali model follow..  12  37...ENFAIDLIAEQPVSQVGSRVISCDGGGGALGHPRVYINLDK-TGTCGYCGLQFRQQ..................................................................................................................................................................... 94
24 -9.9906g2j_R mol:protein length:116 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial  ali model follow..  12  57...ENFAIDLIAQQPVNEVEHRIIACDGGGGALGHPKVYINLDK-TGTCGYCGLQFKQH..................................................................................................................................................................... 114
25 -9.8701olt_A mol:protein length:457 OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE  ali model follow..  11  54....................................SLYVHIPFCHKLCYFCG-------------NKIVTRQQHKADQYLDALEQEIVHRAPLFAGVSQLHWGGGTPTYLNKAQISRLMKNADAEISIEVD------------------PREIELDVLDHLRAEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDL------IYGLP 215
26 -9.7504fhc_A mol:protein length:368 Spore photoproduct lyase  ali model follow..  8  108.........................................ATGCMGHCHYCYLQTTLGSKPYIRVY-----------VNLDDIFAQAQKYINERAPEITRFEAA-DHLTHSLKKAIEFIGADYGRLRFVTKYEH-VDHLLDATRFRFSINSRYVINHFEPGTSSFDGRLAAARKVAGAGYKLGFVIYRHEGWERGYFELFQELARQLEGMDLS.......... 284
27 -9.7005lnk_b mol:protein length:96 Mitochondrial complex I, 13 kDa subunit  ali model follow..  12  37...ENFAIDLIAEQPVSQVGSRVISCDGGGGALGHPRVYINLDK-TGTCGYCGLQFRQQ..................................................................................................................................................................... 94
28 -9.3206gcs_M mol:protein length:136 NUMM SUBUNIT  ali model follow..  12  75...PYAGIELIAQQPVRFVHGNTAVCDGAPGAQGHPKIFINVDA-SHACQYCGTRYEKE..................................................................................................................................................................... 135
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.