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Query: 2uw1_A mol:protein length:338 PLASTID DELTA4 MULTIFUNCTIONAL ACYL-ACYL CARRIER PROTEIN DESATURASE, from PDB1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MQVTHSMPPQKLEIFKSLDDWARNNVLIHLKSVEKSWQPQDYLPDPVSDGFEEQVRELRERAKEIPDDYFVVLVGDMITEEALPTYMSMLNRCDGIKDETGAEPSAWAMWTRAWTAEENRHGDLLNKYLYLSGRVDMRKIEKTIQYLIGSGMDIKSENSPYLGFIYTSFQERATFISHANTAKLAQHYGDKKLAHICGSIASDEKRHATAYTKIVEKLAEIDPDTTVIAFADMMRKKITMPAHLMYDGSDELLFKHFTAVAQRLGVYSALDYCDILEFLVDKWNVERLTGLSDEGRKAQEYVCELGPKIRRLEERAQGRAKEAPTMPFSWIFDRQVKLLast
1 -101.000PF03405.14; E1ZCJ2_CHLVA/69-399; Fatty acid desaturase  ali follow..  59  1.........EQLDVVASMDKYAEEHVLPILKPVEKCWQAQDFLPHPESPDFLDHVHQLQQRTKEVPDDYFVCLVGDMITEEALPTYMAMLNTLDGVRDETGAAPTPWGRWTRQWVAEENRHGDLMNKYCWLSGRVDLRQVEVTIQNLIGSGMDPKTENNPYLGFIYTSFQERATKVSHGNTARMAAEYGDEVLGKVCGAIASDESRHEIAYTRIVDEFFRQDPNNAMLCFADMMRKQIVMPAHLMDDGKHRNLFTDFSEVAERLGVYQASDYCDIMEHLVARWDIEHREGLRGEAAEAQEYLMKLPTRFRKLSERAAARKSKPARVQFSWIF...... 331
2 -22.300PF11583.8; G0G4P5_AMYMS/7-282; P-aminobenzoate N-oxygenase AurF  ali follow..  9  2...............PDREKTADRLLK---SSANKFYDPDVDIDWTAPLVEGKRFILEERSSDRLTPEQRIELGKHEVASTTGLWFEILLMQMLLKEVYEQDPTSAHAQFALTEIADECRHSTMFARMASRIGC------PAYGPVPWLRRLAKLMPTISYGPARYGAVLVAEEVLDRLQREQMTDEGVQPLVRMVNRIHVLEEARHVTFAREEVTRGMAKLSKAEIGYQQFIIAVIS.................................................................................................... 224
3 -20.900PF11266.8; Q8DJB4_THEEB/11-228; Long-chain fatty aldehyde decarbonylase  ali follow..  11  1..........................................................DYHSDRYKDAYSRINAIVIEGEQEAHDNYIDLAKLL----------PQHQEELTRLAKMEARHKKGFEACGRNLSVTPDMEFAKAFFEKLRANFQRALAEGKTCLLIQALIIESFAIAAYNIYIPMA----DPFARKITESVVKDEYSHLNFGEIWLKEHFESVKGELEEANRANL........................................................................................................ 164
4 -19.200PF02915.17; O26850_METTH/9-145; Rubrerythrin  ali follow..  13  3........................................................................LTKAFIGESQARNRYTFYAKIAKKE-----GFEQISEIFLTTADNEREHAKWLFRLINDLK----EVGEDLSSIVVDAEAPLTLGTTDENLIAAIEGEHYENSEMYPEFADVAEEEGYPEIAKRLRAIAEAEKHHEERYRKLL........................................................................................................................... 137
5 -18.500PF04305.14; C1MSR4_MICPC/21-274; Protein of unknown function (DUF455 topsan)  ali follow..  14  1...NTPSAHDKALMTEEIHSMWRTGVMTVTHDLDAPAPRQLERP-DARVKLVEPSCAPRLGKGGSPESRVAILHSLAHIESWAIDLSWDAIARFG---RAEKMPRKFFEDFLAVAADEARHFSLLAARLVELG---SYGALTAHDGLWESATETRDSLEARLVIEHCVHEARGLDVLPGTIAKFRRFGDDPSADLLEHVIYPEEITHCAAGVRWFTYLQNRMGGALVRFHVIVRKHF..................................................................................................... 230
6 -15.600PF00268.21; RIR2_SHV21/5-277; Ribonucleotide reductase, small chain  ali follow..  10  10......................VGFLELTKETWKNRWFPSQV-------PLQGDVCCVDMLNERDLEFYKFLFTFLGMAEKLVNINIEDLLSQF--------DSHDISHYYAEQMAMENIHGKVYANILNMLFKNNITEVSALQEKLRWLNGRVTEASDKAEKILLFLLVEIFFISSFFSIGLFRVRGIMNGICLANDYIARDEMLHTSAAALLYNTMTKSSERPSEDWIYKLFREAV.................................................................................................... 221
7 -14.700PF09968.9; A6LNR3_THEM4/28-188; Uncharacterized protein domain (DUF2202 topsan)  ali follow..  10  2.....................................................................TESIMQMRKEEKLARDVYLVFYDLWGIR-------------FSNIAGAEQQHMDAVLTLIKKYDSNDPIKFEDENLQALYNQLVEQGSKSLEDALIVGATIEDLDIYDLE---EFLKITDNQDIEFVYKNLIKGSENHMRAFVSQLSRF........................................................................................................................ 141
8 -14.500PF02332.18; G7ZAS0_AZOL4/60-290; Methane/Phenol/Toluene Hydroxylase  ali follow..  10  14.KDWTALKCTDWHGFRAPDQEWERTHYQ--RQSTIVGMIQNVVENARRAGAPQRFD------KAWVTVLQNHVGAFKHAEYGLGTALMRAQRY--------GYTQMVNNAILTNASYKLRFAQDLTLYLAEVGSDIGGFDLDAGKAHWLDDPIWQPCREAVEYFAVNLVFEVGELFRSGFVMQVAAAQNDFSTPSVISAAEADYERNLANAVELFALLLR-DP................................................................................................................... 231
9 -13.900PF13668.6; Q11V37_CYTH3/38-167; Ferritin-like domain  ali follow..  12  3.....................................................................TDTLNYALTLEYLEEAFYVQGLAKSGLIDSADMT------IFNQIKKHESAHVVFLKNVLGSAANPSPA------------DFGTAFDSYANFLATAQALEDTGVRAYKGQAGNLIT---NKVALTAALQIHSVEARHASEVRRLR........................................................................................................................... 128
10 -12.700PF05138.12; Q5P3I7_AROAE/1-255; Phenylacetic acid catabolic protein  ali follow..  8  1...........................................................MTQQMTSPEHIEYVLRLGDNALILGQRLSEWCGHAPVLEEDMA--------LANMSLDLIGQARMLLTHAGRLEGRGRDEDQLAFLRTEPNYRNLTLCELPNQDFARTMVRNFLYSSFQKLLWERLMTSSDAELAAIAAKSIKEARYHAQHAGDWVIRLGDGTAESY-ARAQGALDYLWPYTAEFFVATPVDDTVAAAGVGPAWSEL--ETAWEALAMPVLAEATLTTPFRSYGKFGRHSEHMGHLLAEMQIMQRTYPGA---------QW........ 255
11 -11.900PF05067.12; Q9KAU6_BACHD/1-281; Manganese containing catalase  ali follow..  11  8........................................................................LQYHAKPERPDPVYAKKLQEILGGQFGEISGDGKYRDLLMDTGTEELAHVEMLATMIARLLDGAPVGDQEAAAKN--TADYIIASGNLLADFRMNLTAESQGRLQAV---RLYEMTTDPGVRDMLSFLIARDRMHQNQWYAAICEL........................................................................................................................ 193
12 -10.700PF06175.11; Q8CX43_SHEON/3-250; tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)  ali follow..  12  19..IDVARASASLDEL------LIDHCNCELKAAQTAMFLLRRYALNAESGQSLLAWAKPYEEFVYHKDRDIEQFLARDVKKNELVAVLQPNQHFSFAQDLIPPLIRLIK-------EEFHHFEQVLELMHARQIPYRNIRAGRYAKGMMSHVTTHEKNILRDKLIVGAYIEARSCERFAKLAPYL----DAELSKFYVSLLRSEARHFEDYLKLAQLVSSEDISERVAYFGEREAELI.................................................................................................... 237
13 -9.100PF03232.13; H0VHI5_CAVPO/48-217; Ubiquinone biosynthesis protein COQ7  ali follow..  8  1...................................................................AVDRIIRVDHAGEYGADRLAGQMA---------VLGRTSVGPVIQKMWDQEKAHLKKFSELMVAFRVRPTALMPLWNVMGFALGAGTALLGKEGAMACTVAVEETIAHHYNNQIRMLMEEEKYEELLQLIKTIRDEELEH................................................................................................................................... 134
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.