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Query: 5Y8X Entity 1(prereleased), from PDB1018

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRRLAFLVVAFCLAVGCFFSPVSKAEGVMSGGDGDKVAVGKDGMVATAHPLASKIGAEVLKKGGNAIDAAIAIQYALNVTEPMMSGIGGGGFMMVYDGETRETSIINSRERAPEGAKPDMFLDEDGKVIPFSERSRHGNAVGVPGTLKGLEAAHKKWGTKKMEDLISPSIKLTEEGFPIDSVLADAIKDHQDKLSKTAAKDIFLPDGEPLKEGDILVQKDLAKTFKLIRKEGSKAFYDGEIGRAIADVVQDFGGSMTPDDLSRYEVTTDKPIWGEYHGYDIASMPPPSSGGVFMLQVLKLIDDFHLSQYDPKSFEKYHLLAETMHLSYADRAAYAGDPEFVDVPLRGLLDPDYIKERQKLISLDSMNRDVKEGDPWKYEEGEPNYEIVPQPEDKTIGELast
1 -92.200[E] COG0405 Gamma-glutamyltransferase  ali follow..  30  2..................................NKSVIGTKQMVVSPHYLASQAGNRILDKGGNAFDAAVAVSACLAVVYPHMTGLGGDSFWLTFHQETKAVKVYNGSGRSGKNVTRDVYKGKSAIPLRG-----IDSAITVPGMVDSWDAVLKEYGRLSLADVLEPARDYAQNGFPVSADQCRHTEKNIELLSTPYTADIFTRRGKAPVPGERFVQKELADSLNLIAEKGRSAFYEGDLAQRIVSHLQNNGSYMTIDDFKAHRGEWAAPVSSDYRGYSVYQAPPN-SQGFTGLLTLNILENYDFTQIEHGSFEYYHVLVEALKKSFLDRDAVLTDPAFADIPLERLLDKRYAKQLAEEIGYLAIPAESRP------VGSDTAYAAVIDADGNAVS. 353
2 -78.800[E] KOG2410 Gamma-glutamyltransferase  ali follow..  27  82...................DENGKPQFDWPTPSGSLFAHYKKAAVTSDHGLCSEIGRDVLIEGGNAVDAMIASLLCIGTVNPQSSGIGGGFVMTLYNASTGMCQTINARETAPAAATETMFVDNPKE------SVMGYKSIATPSELHGFWTVFNMYGKVSWARLFQPSITLAHDGFPVSSNLAMRKF--------SRDIFVNPKTNRVYEEGDILKRQRLASTYALLANDPVELFYKGGMAQTIAGEITDNGGFVNESDLASYETTIDDPLLSTHLDYEMCGPPPPSSFVITQNIIQVMAQYYKDGQVDLDDPLVYHRLIEAEKFAYAQRT-KLGDVKFVESAVDEMMTEEYTKKIASLIKDTAQTLDYYGGEKKDMPDHGTSHVSIIDSHGNAVS. 455
3 -8.760[R] KOG2782 Putative SAM dependent methyltransferases  ali follow..  14  29.................................................PVLCDTAIEYLVPGGTYFDMTF--------------GAGGHTRRLLEKCPEAKVYALDRDPLAHQLARDMSPLLGKFSDLPKLFKEHGLAKNSVDGMLFDF--------------CSSMQFDEAVRGFSISRDGPLDMRMDGGHSGGVTAADVL----------ANVEEGDLVKILRMYGEE-----AAKKIARGLVDARNALFKIETTKQLAD---IIENIMDGGTRKDKLRRPAHSAT---KTFQAIRIFVNNELNEINYGMVLANEILRVDGRLVLEDT................................................................... 281
4 -7.230[M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis  ali follow..  15  17.................................................PVLPQEVITGLRPGGRYLDVTV--------------GGGGHSRLILEAAPDVKLTAVDQDGDALTAAKQEL------AEFGEQVKFVRSNFAAYDFPSTSFDGVLADLG------VSSYHLDTPERGFS---------------FRHQASLDMRMDQRQSLSAADVINDWDEVELANIFFKYGEERL-----SRRIARRIVEKRPFHTTTELAE---AIASSVPPKYRYGRIHPA-------TRVFQALRIVVNDELKSLETFIEKAPKALVPGGRIAFHSLEDRLVKHGLRNSPLLKVLTKKPIIATDDEIANNPRSRSAK........................... 287
5 -5.960[M] COG0812 UDP-N-acetylmuramate dehydrogenase  ali follow..  15  13.........................................VGEVRVNESLAHHTTWKI---GGPA-GLKNTMKLIQETGCKWR--IGRGSNILVSDKGLRGVTIKLDKGLDHLEVNGESITVGAGFPVVKLATVISRQGLGIPGSVGGAVFMNAGAHGSDISQILTKAHVLFPDGFSLTRGDKEDIKKKLQKNKDYRRDT------NHPTCGSVFRNPLPEYAGQLIEKAGLKGYQIGQISTMHANFIVNTGDA-KAADVLALIHHVKDTIQKQY--------------QMNMETEVELI................................................................................................. 298
6 -5.450[S] COG5546 Small integral membrane protein  ali follow..  15  16..........................................AILGAIFLLAQQLGIKLPSNIADIANTAVTLLVLLGVVDPTTKGLSDSEQALTYHEPKK......................................................................................................................................................................................................................................................................................................... 75
7 -5.430[S] KOG4148 Uncharacterized conserved protein  ali follow..  13  3..................................................................................................................................................................................................................................................................................................................PHLDVNNQKQCADLIRALEECHKSFGKFFGECNTIKYELKACLTKDRNDKARLNRENARMRKKVIEENRKKEEIEERILTDRILQQERKKSH 94
8 -4.720[R] COG3042 Putative hemolysin  ali follow..  20  1MKIISFVLPCLLVLAGCSTPSQPEAPKPPQIGMANPASVQKGGTLIPVQTAQGVSNNCKL-PGGETIDE......................................................................................................................................................................................................................................................................................................................................... 71
9 -4.680[R] KOG2745 Mitochondrial carrier protein  ali follow..  10  16................................................................NVWIRFGLRLGVSAALHPFE-------------------------------SKTLIQLGYEPIAPLPGKSILGKPIMKLPNIFQYAGHIRRIDGFYGCYRGLAPKLVGSLVAMVVSDRVADQLGLEQPEENKDDSQKSLKRDIVLMVSGVVASHPSIVGSVAEIKSEGIAGFFAGLVPKLLGDLACLVLSSSTIYILNKYKDKLGRQYNSGFTQFAVSSLLYP----LQVVSTCSAVSGSRLMAAQPPIMPAYRNWVDCWNDLQVRGE.................................................................. 283
10 -4.640[H] COG0157 Nicotinate-nucleotide pyrophosphorylase  ali follow..  10  85.....................................................EPGQVVAEIHGSLDALLMGERVALNLAM-GLSGIATLTKIYVEKIADLPACLVDTRKTTPGLRLLEKYATAMGGAINHRMGLDDAVMIAAGGIGKAITRIRSQIPYTLTIEVVKEALEYKADIIMLDNMPVDLMRQAVQLIRQQDNGVKIEASGNV------------LETIRAVAETGVDYISSSAPITQS......................................................................................................................................................... 277
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Godzik A. Fold recognition methods. Methods Biochem Anal. 2003;44:525-46. Review.