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Query: 4njg_A mol:protein length:230 7-carboxy-7-deazaguanine synthase, from PDB1018

Results of PSI-BLAST search in nr85s
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# E-value Template Links and tools%idFirst MGSSSSGLVPRGSHMTYAVKEIFYTLQGEGANAGRPAVFCRFAGCNLWSGREEDRAQAVCRFCDTDFVGTDGENGGKFKDADALVATIAGLWPAGEAHRFVVCTGGEPMLQLDQPLVDALHAAGFGIAIETNGSLPVLESIDWICVSPKADAPLVVTKGNELKVVIPQDNQRLADYAKLDFEYFLVQPMDGPSRDLNTKLAIDWCKRHPQWRLSMQTHKYLNIPLast
1 3.000e-72UniRef50_A0A0H3KB22 7-carboxy-7-deazaguanine synthase n=1737 Tax=root TaxID=1 RepID=QUEE_BURM1  ali  100  1..............MTYAVKEIFYTLQGEGANAGRPAVFCRFAGCNLWSGREEDRAQAVCRFCDTDFVGTDGENGGKFKDADALVATIAGLWPAGEAHRFVVCTGGEPMLQLDQPLVDALHAAGFGIAIETNGSLPVLESIDWICVSPKADAPLVVTKGNELKVVIPQDNQRLADYAKLDFEYFLVQPMDGPSRDLNTKLAIDWCKRHPQWRLSMQTHKYLNIP 210
2 2.000e-62UniRef50_F6G1S0 7-carboxy-7-deazaguanine synthase n=278 Tax=root TaxID=1 RepID=F6G1S0_RALS8  ali  67  1..............MTYAVKEIFYTLQGEGANTGRAAVFCRFAGCNLWSGREADRAAAVCQFCDTDFVATDGTLGGKYATANALADLVAAQWPATGGQPLVVCTGGEPLLQLDRPLIDALHARGFEIAVETNGTVAVPEGIDWVCVSPKMGAELVVTRGDELKVVIPQPGQDLDAYERLDFRHFFLQPMDGPLARQNTALAVELCQRRPRWHLSLQTHKMLGI. 211
3 6.000e-62UniRef50_Q89SC0 7-carboxy-7-deazaguanine synthase n=616 Tax=root TaxID=1 RepID=QUEE_BRADU  ali  61  1..............MSYAVKEIFLTLQGEGAHAGRASVFCRFAGCNLWSGREADRQDATCKFCDTDFVGTDGTLGGRYASAVELADTIAAQWTASNDNRYVVLTGGEPLLQVDDALIDALHARGFEIGVETNGTIAAPDGLDWICVSPKGGSELVLRRGHELKLVYPQALAAPETFEGLAFERFSLQPMDGPEVAENTARAIDYCLRHPQWRLSVQTHKSLGI. 209
4 1.000e-61UniRef50_Q3SPB9 7-carboxy-7-deazaguanine synthase n=17 Tax=root TaxID=1 RepID=Q3SPB9_NITWN  ali  65  1..............MSYAVKEIFLTLQGEGAHAGRAAVFCRFSGCNLWSGREEDRASATCRFCDTDFVGTDGTLGGRYASADALADTVAGQWAGPAAHRYAVLTGGEPLLQVDKAFVDALHARGFEIGIETNGTLAPPDGIDWLCVSPKAGADLRIRRGHELKLVYPQADARPEDFADLAFDRFSLQPMDGPDAAENTARAVDYCLRHPQWRLSLQTHKTLGI. 209
5 1.000e-59UniRef50_A0A0K2G6P4 7-carboxy-7-deazaguanine synthase n=8 Tax=Bacteria TaxID=2 RepID=A0A0K2G6P4_NITMO  ali  25  2................LRVTEIFHSLQGESTFAGRPCVFVRLTGCPLRCTWCDTEYA---------------FYGGTEQSIDDIIARVRAY-----GCPLVEVTGGEPLAQPDAALLKRLCDEGFTVLLETSGALDAVDQRVHIILDIKCPGSGMAERMHNVERLRSQDEAKFVLQDRADYEWAKDVMIRYGLTERCTHLAEWILADRLPVRFQLQMHKFIWAP 207
6 1.000e-58UniRef50_E1RHZ6 7-carboxy-7-deazaguanine synthase n=3 Tax=Euryarchaeota TaxID=28890 RepID=E1RHZ6_METP4  ali  26  1................MKVFEIFPSIQGEGPYQGIPSAFIRLSGCNLRCRWCDTPKTQDGS-------------SSEEMTVDEVFGQVKKL-----GLSHVCITGGEPLIQQDELLLKDLHEDGYIVEIETNGTIDPVPVMEYVCMDIKCPSSGEKSFAPFVKKLRPSDCVKFVVEGKEDLEYMTGLLDDIPSYVEDSRFIADYIMKLKRVRFQLQLHKILGV. 203
7 4.000e-58UniRef50_UPI0004E136E9 7-carboxy-7-deazaguanine synthase n=1 Tax=Desulfovibrio frigidus TaxID=340956 RepID=UPI0004E136E9  ali  49  1..............MSFNVNEIFYSLQGEGHHTGRPAVFCRFSGCNLWTGQDVDRTKAICQFCDTNF-ITAAESGGTFETASELITAILSYFPDYKNQDYVILTGGEPALQITQELISGLKENGLEVGIETNGTKPLPKDIDWVTVSPKAGTKLAITSGNELKLVWPQESILLADFEDLNFEHLYIQPRGGADSSKSTELAIEICLKNPVWKLSLQTHKLIGI. 211
8 4.000e-58UniRef50_Q478F5 7-carboxy-7-deazaguanine synthase n=21 Tax=Bacteria TaxID=2 RepID=Q478F5_DECAR  ali  27  1..............MALRITEIFYSLQGEASRVGLPTVFVRLTGCPLRCSWCDTTYS---------------FTGGEAATVESVLAEVAKYPARQ-----VCVTGGEPLSQKDLPLLAALCNAGYDVSLETSGALDVSAVDPRVAMDLKAPDSAESARWENLTVLTPRDEIKIVIASRGDYEWARVLFSPAQGVIEPQSLAEWILEDGLNVRFQLQLHKLLW.. 206
9 7.000e-58UniRef50_U6B5B3 7-carboxy-7-deazaguanine synthase n=376 Tax=root TaxID=1 RepID=U6B5B3_9RHIZ  ali  54  1..............MKFYVKEIFLTIQGEGAHAGRVSVFCRFTGCNLWSGREKDRSSAKCRFCDTDFVSIDGTKGG-SYTSETLANAILSEWIGGKDNRYCVLTGGEPLLQVDTPLIDALHKRDFKIAIETNGTIKAPEGIDWICVSPKEGCDLKIKTGNELKLVFPQINAHPDNYSMFDFDRYSLQPMDGSDLAKNTNLTIEYCSKNPKWRVSIQMHKLIGV. 209
10 3.000e-56UniRef50_A0A1Q7ATH3 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A1Q7ATH3_9BACT  ali  24  1................MRITEIFFSIQGESSYTGRPCVFVRLTGCPLRCTWCDTAYA---------------FHGGTERSLESILAEVER-----HECRLVEITGGEPLAQSEVHLITALADRGHTVLIETSGALDIAPVDPRLIMDLKCPGSSMEDRWANLPKLKPTDEVKFVIKDRGDYEWAVVLLSPVFGELDPRTLAEWVLAYRLPVRLQLQLHKFIWDP 206
11 3.000e-56UniRef50_E8R001 7-carboxy-7-deazaguanine synthase n=8 Tax=Bacteria TaxID=2 RepID=E8R001_ISOPI  ali  25  65..TRRLAPLRDKTPGQVRLHEVYRSIQGEGTWAGLPCVFVRLTACHLRCVYCDTPHA-------------FVFREGGDFTIEAIVARVAELAE---PGGLVEVTGGEPLLQPELPLMTALADAGFEVLLETSGSLDIAPVDVHIIMDLKTPGSGEENLWTNLDHLKPTDNLKFVVTNRADFDWTLEIVRRHDLTARCRDLAEWILKSRLPLRMQLQLHKLIWHP 288
12 5.000e-56UniRef50_A0A1F8ZM62 7-carboxy-7-deazaguanine synthase n=6 Tax=Bacteria TaxID=2 RepID=A0A1F8ZM62_9DELT  ali  25  1..............MILRISEIFLSIQGESTYAGLPCIFVRLTGCNLRCKWCDTTYAQMLE-------------KGEEFSVEQIIKEVKRFK-----CKLVEVTGGEPLLQDEHELLKKLVKLGYEILIETNGSISLKSVNPNIIVDVKCPSSGHNFILENLKYITLRDEIKFVIADRKDYEYAKILFAPVYPKMSSQELASWILKDCLQVRLQPQIHKFIW.. 208
13 1.000e-55UniRef50_D5CMS7 7-carboxy-7-deazaguanine synthase n=24 Tax=Bacteria TaxID=2 RepID=D5CMS7_SIDLE  ali  23  8...............SLRISEIFYSLQGETSRVGLPTVFVRLTGCPLRCSYCDTAYA---------------FTGGQSMQLSAIMDEVASYAPR-----YVTVTGGEPLAQKNCLFLLRACDAGYEVSLETGGALDVSGVDARVVLDIKTPGSGEKNLWGNLQHLGRHDEIKFVLCGEADYQWAKQVMQEHALAQRCTELAEWILRDRLPVRLQVQLHKLLW.. 212
14 2.000e-55UniRef50_A0A0D0TEF2 7-carboxy-7-deazaguanine synthase n=723 Tax=root TaxID=1 RepID=A0A0D0TEF2_PSEFL  ali  25  4...............TLRITEVFYSLQGETRTAGLPTVFVRLTGCPLRCQYCDSAYA---------------FSGGTVRTLDDILEQVAGYRPR-----YVCVTGGEPLAQPNIPLLKRLCDAGYEVSLETSGALDISAVDPRVSVDLKTPDSKEANRYENIDLLTANDQVKFVICSRDDYDWASVLFSPSHHDLNARDLADWVVADNLPVRLQLQLHKYLW.. 209
15 2.000e-55UniRef50_A0A1G0R8U8 7-carboxy-7-deazaguanine synthase n=1 Tax=Ignavibacteria bacterium GWF2_33_9 TaxID=1798430 RepID=A0A1G0R8U8_9BACT  ali  24  2..........KTENTKFNISEIFYSIQGEGSRAGMPCVFIRLQGCNFRCDWCDTPYAL------------ESNDDAEWMTGAQILEKVNSFE-----CDFVEFTGGEPLFQKDVDLINDFVDNGFLVAIETNGTFENLNSAAVKIMDIKCPGSRMQRFNDNFKYLTQNDELKFVVLNKSDFDWAVVLFSPVFGKLEPVQLSEWILESHLPIRLQLQIHKFIWEP 217
16 2.000e-55UniRef50_A0A2P6VSR0 7-carboxy-7-deazaguanine synthase n=1 Tax=Thermoplasmatales archaeon SW_10_69_26 TaxID=1919232 RepID=A0A2P6VSR0_9EURY  ali  27  1................MRITEIFYSLQGEGLLAGVPTVFVRTTGCHLRCSWCDTAYS---------------FYGGEELSVDEILDEV-----RQHPTDNVCFTGGEPLIQDEAPLVETLLNEDYEVVIETSGSLDLSAYRERLSVDVKLPSSEMENELGELEHLQPHDQVKFVVASQEDYDYAKSVIDKVSTGKNETWLAEQILEDGLDVRFSMQMHKLLW.. 206
17 3.000e-55UniRef50_R9T6U3 7-carboxy-7-deazaguanine synthase n=5 Tax=Euryarchaeota TaxID=28890 RepID=R9T6U3_METII  ali  25  1................MKVSEIFFSIQGEGVLMGTPTIFVRFSGCNLDCSWCDTEYA-------------KNDADAKEMSVNNILDEIEKY-----NSPFVSLTGGEPMIQEIIDFINALLEESYHITIETNGSIPLDSIPIMISMDMKCPSSGMSEMYDNLSFLSPRDQLKFVIADRVDYLFAKPVIMTPVGGMDLKPLAEWVIQDCPMVRVMPQLHKLIW.. 205
18 3.000e-55UniRef50_A0A1W1I3M7 7-carboxy-7-deazaguanine synthase n=13 Tax=Bacteria TaxID=2 RepID=A0A1W1I3M7_9BACT  ali  20  1................MRITEIFHSIQGESTYAGEPCVFVRLTGCPLRCTWCDTAYA---------------FHEGQEMSLADVMTAVKSY-----GCRLVEVTGGEPLAQSQIELIESLCETGYKVLVETSGAIDISPVDRRIILDVKCPGSGMTERWPNLAQLTAKDEVKFVVAGRSDYDWAVVLMSPVFETLEPRQLAEWILRDRLPIRFQLQLHKFIWAP 206
19 5.000e-55UniRef50_A0A1Z8ZF91 7-carboxy-7-deazaguanine synthase n=6 Tax=Bacteria TaxID=2 RepID=A0A1Z8ZF91_9PROT  ali  45  1..............MIYSVKEIFLTIQGEGYNSGRKATFCRFSGCNLWNGLETSKKTAKCNFCDTDFVGVDGINGGKYTLSSLVSKIEKVSKENNKEKKLIVFTGGEPLLQLNEDLIKNLKKKNYEIAIETNGTINPPKGVDWICVSPKIKNKIVLNYGNEIKVVYPQKGINLNEFENLRFEHYYLQPLHNEKYSQNLKKTLEAIMKHPKWKLSLQTHKFIGV. 209
20 5.000e-55UniRef50_A0A1B1YVA1 7-carboxy-7-deazaguanine synthase n=14 Tax=Proteobacteria TaxID=1224 RepID=A0A1B1YVA1_9GAMM  ali  23  1MTVHAQAAPAKVPAVRLKITEIFHSIQGEGLTAGVPTVFVRLTGCPLRCSYCDTAYA---------------FTGGEYVELPAILSRVAAF-----ATSHVTVTGGEPLAQACLELLSALCDAGHQVSLETSGALDVAPVDRRVVLDLKTPSSGECARYANLDLLQSGDQVKFVLTDRADYDWAVVLFSPAFGLLDAATLADWMLADRLPFRLQLQLHKLLWVP 224
21 2.000e-54UniRef50_A7HD72 7-carboxy-7-deazaguanine synthase n=9 Tax=Proteobacteria TaxID=1224 RepID=A7HD72_ANADF  ali  29  1................MRVTEIFFSLQGEGTRAGRPCVFVRFTGCDLRCGYCDSAYA---------------FHGGRELTRAEILAEIAR-----HPAKLVCLTGGEPMLQRELPLARELVARGHEVTVETHGQRPLDALPPIRIVDVKTPGSREEKDLAYLDGLRPQDEVKFVVCSEPDYRWSVDVVSPAWGEVEPRELARWILRDGLDARLSLQIHKVIWGP 205
22 2.000e-54UniRef50_Q2FS67 7-carboxy-7-deazaguanine synthase n=36 Tax=root TaxID=1 RepID=QUEE_METHJ  ali  28  24.....HQPAAQSSGMK--IAEIFTSLQGEGLTSGYPTIFIRLAGCNLSCSYCDTPAS---------------RQGGMDMNVSEVVAGALLQKP-----HYVCITGGEPLLQKDEELARQLIKAGKMVSIETNGTVPFDDLPISICMDVKCPSSGEFSNINLLSDLKSTDSVKFVVGTDDDLQYAEKVIMSHPTKAEIFRIASYILSRNLPARMQLQLHKFIGLP 234
23 2.000e-54UniRef50_A0A1D2R7P2 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Candidatus Altiarchaeales TaxID=1849260 RepID=A0A1D2R7P2_9EURY  ali  26  1................MLVNEIFYSIQGEGVWVGIPMVFVRLAGCNLSCSWCDTPDA-------------RGRYKGVEISEGDILKKVD-----GYGCDWVCITGGEPLEQAGEELIKRLIEGGYEIIVETNGSLEINKIIVHISMDWKLPGSKMDSRMENLNHLSANDQLKFVVKDKEDYKHAKQVIFQPVGGIEIKDLIEWVREDKLKVRLLPQLHKILNI. 207
24 3.000e-54UniRef50_I7KZN1 7-carboxy-7-deazaguanine synthase n=9 Tax=Methanomicrobiales TaxID=2191 RepID=I7KZN1_METBM  ali  26  1................MIVSEIFRSLQGEGKNQGRPCTFIRLAGCNLRCAWCDTPYA---------------RKGGKEMSVAQILDLI-----WLQNGKHICITGGEPLLWAEEVLELLRKFHGYNVEIETNGTLDFREMQAYICMDVKCPSSGEKSNLALLRHITPRDSVKFVVADENDLLYARAVMAHYVEGADYRAIAEYIVEEDLPVRFQVQLHKILGV. 201
25 3.000e-54UniRef50_A0A1S1V9A1 7-carboxy-7-deazaguanine synthase n=17 Tax=Firmicutes TaxID=1239 RepID=A0A1S1V9A1_9FIRM  ali  24  1..............MLLKVNEIFLSIQGEGISAGYPTIFVRLTGCNLRCSYCDTTHAY---------------NEGSDMAVEKVLEEIESL-----GYKRVCITGGEPLLQEKGLLKLLEGLSDYEVSIETNGSVDLLRENHRFTMDIKTPSSEESERLENLKLLRDQDELKAVIGSRKDYLWALGVISPIFGMIEPEEIINWILEDKRDIRFQIQIHKFIWNP 207
26 5.000e-54UniRef50_C6XA92 7-carboxy-7-deazaguanine synthase n=8 Tax=Bacteria TaxID=2 RepID=C6XA92_METGS  ali  24  1..............MKLRIHEIFHSLQGESSRVGLPTVFVRLTGCPMRCVYCDTAYA---------------FHGGSSMEIDDIMQKVAEY-----GAHYVTVTGGEPLAQRDCHLLTRLCDAGYSVSLETGGAMDIANVDPRVSVDIKTPGSLEKNLWGNLAHLKAQDEVKFVLCDHADYLWAKVLFSPVYSQVNPTELAEWILADKLPVRMQVQLHKILW.. 206
27 5.000e-54UniRef50_A0A1V6CS37 7-carboxy-7-deazaguanine synthase n=3 Tax=Bacteria TaxID=2 RepID=A0A1V6CS37_9BACT  ali  24  1........MPAKNPMGLTVNEVFHSIQGEGTRAGLPCAFVRLTGCNLRCDWCDTRHAW---------------HEGSQMPLEEVMQAV-----GRAPCRRVEVTGGEPLMQNALALLGALCDAGYETLLETNGSMDISGVDERVIVDFKCPSSLMHNRWANVHLLTPRDEVKFVLADRGDFEFRCPVISPVINRLPPADLASWILDDLQEVRLGLQLHRIIW.. 216
28 5.000e-54UniRef50_A0A1H6FCP1 7-carboxy-7-deazaguanine synthase n=156 Tax=Bacteria TaxID=2 RepID=A0A1H6FCP1_9GAMM  ali  59  1..............MTYSVKEVFYTLQGEGINAGRPAVFCRFAGCNLWSGLEQDRHKASCSFCDTDFVGVNGKGGGKFATARQLALHIKHYFPETESIRGVVFTGGEPLLQLDTPLIEALHALDFEIAVETNGTIAVPDQLDWICVSPKAGTDLVQTSGHELKLIYPQNGICPETFESLPFQYFLLQPLDSNKQQQHLQQAIAYCKQHPHWRLSIQTHKWLDIP 215
29 6.000e-54UniRef50_A9IPG0 7-carboxy-7-deazaguanine synthase n=2 Tax=Bordetella petrii TaxID=94624 RepID=A9IPG0_BORPD  ali  63  175.......PPGRGHRMTYSTKEIFKTLQGEGAQAGRAAVFCRFAGCNLWSGREADRAGAVCTFCDTDFVGTDGPGGGKFASAAQLADAIAAAWGPGTQDRYVVFTGGEPLLQLDAALLQAVHGHGFTVAIETNGTLPAPAGIDWICVSPKGSARVVIERGHELKLVYPQAEARPEAYAHLDFQHFFLQPMDGPARAANTQQAVQYCMQHPQWRLSLQTHKYIGIP 391
30 7.000e-54UniRef50_A0A2V7U9R1 7-carboxy-7-deazaguanine synthase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7U9R1_9BACT  ali  25  46.PPTRSERAAAPAVLT--VNEVFFSIQGEGTRAGQPCVFVRLTGCPLRCVWCDTAYA---------------FHEGTRRAEEDLIAEIER-----HPCRLVELTGGEPLSQPAFPFITRLLDAGWQVLVETSGHV-LLEGLDRAIMDIKAPGSGETHRMENLELLKPTDEVKFVIAGRADYEWRCPVFSPVHGVLEPGELAGWILEDGLPARLQVQLHKYLW.. 262
31 8.000e-54UniRef50_A0A151EAN2 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Thermoplasmatales (miscellaneous) TaxID=1919231 RepID=A0A151EAN2_9EURY  ali  25  1................MKINEIFYSLQGEGLLTGTPSVFLRTSGCNLRCSFCDTTYAY---------------EKGTIMNIKEILDEVTKF-----HCNYVCLTGGEPLLQKQTQLINILLSKNYKVCLETNGSKSIKRFVLFISLDIKCPSSGVHKQMNNILYLKKKDQLKFVIKNKQDYEYVCPVFFQPVWGANPKKLASWILDDGLSVRLSLQIHKIIW.. 203
32 8.000e-54UniRef50_A0A1D2RFE9 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Altiarchaeales archaeon IMC4 TaxID=1878999 RepID=A0A1D2RFE9_9EURY  ali  24  1................MKINEIFFSIQGEGKYAGKPQVFIRTQGCNMHCKWCDSSYA--------------RGSGGKEMPVSDIIKDIEKY-----DCKSVCITGGEPMLQMEGLLVRELKKNRYEIVLETNGSREIFGQVGCVSMDAKPPSSGEKSDLRIIEKLKKKDQLKVVIADRNDYEFAKKIWPCRADIIDAKKLCGWVLEDNLDVRVIPQLHKIIGV. 200
33 1.000e-53UniRef50_I6Z3S4 7-carboxy-7-deazaguanine synthase n=3 Tax=Bacteria TaxID=2 RepID=I6Z3S4_MELRP  ali  22  2................LKVNEIYYSIQGESSRAGLPCVFVRLTYCNLRCSYCDTEYA---------------FYDGIDMSKEEILEKVNEY-----GCKLVELTGGEPLVQKELDLMKSLCDSGYEVMLETGGSLPIDNVDKRVIMDLKCPSSKMKNRYENIEFLKPGDEVKFVIGDRNDYEWSLNKIKEFELDKKCVTLLNWILADKLNVRFQLQMHKYIWKP 207
34 1.000e-53UniRef50_A0A2E1PHU3 7-carboxy-7-deazaguanine synthase n=6 Tax=Bacteria TaxID=2 RepID=A0A2E1PHU3_9GAMM  ali  46  1..............MNYRIKEIFYTQQGEGKNTGMNSVFIRFTGCNLWSGKEKNRGNAICNFCDTDFYGTDGINGG-IYTKEELLSKVRSIWLNEDENINVVLTGGEPLLQVDQQLINFFKENNLYIAIETNGTIIPPSGIDWICMSPKPKTKINVSSGDEIKFIYPQQNFNPRMFEAMNFSHFYVQPMDSEKLHENVNETIKFCMQNPKWKISLQSHKILGI. 208
35 1.000e-53UniRef50_I5AYH9 7-carboxy-7-deazaguanine synthase n=18 Tax=cellular organisms TaxID=131567 RepID=I5AYH9_9DELT  ali  28  1..............MSLEICEIFYSLQGESTRAGLACVFVRLSGCNLSCSWCDTTYAAVQPV---------------SMTIDQIVGRVAAFE-----CPMVEITGGEPLIQTQTPLISALLEKGFQVLLETNGSLSIVDRACIRIMDVKCPSSGESFLLDNLNHMTARDEIKFVVGSRQDYEYAKVHICPVFEAIELSDLAAWILKERLGARLSLQQHKIIWDP 209
36 2.000e-53UniRef50_A0A1W1UK14 7-carboxy-7-deazaguanine synthase n=1 Tax=Peptoniphilus asaccharolyticus DSM 20463 TaxID=573058 RepID=A0A1W1UK14_PEPAS  ali  25  1..............MKYDINEIFYSIDGEGPNSGKLSVFIRLNYCNLRCVYCDTGYALGRKD--------------NFYTLEEIVEQVESY-----GIKSVTITGGEPLEHDLKPLISRLLSLEYEIDIETNGSLDIRKYLVNIILDIKTPSSKMEKLYENLSKLRPNDVVKFVA-SENDMDFVLNIIQKYYTSAKNIDKIVEYIKEHLEVRLQLQIHKYIWDP 205
37 2.000e-53UniRef50_C8VWI0 7-carboxy-7-deazaguanine synthase n=16 Tax=root TaxID=1 RepID=C8VWI0_DESAS  ali  22  1................MKVNEIFYSLQGEGITAGYPTVFIRLTGCNLRCLYCDTVYAY---------------EEGQEMSVKDVADRVHEY-----GAHYVCITGGEPLQQKAELKLLLSLLNRYTVTIETNGSLSLEDLYCHFAMDIKTPGSGMHNDFSNIEFLRSKDEIKFIIGSRTDYDFARGIIEKYKLAQKVIFLAQWVLEDKLFVRVQLQIHKYIWEP 206
38 3.000e-53UniRef50_A0A0G3WEL0 7-carboxy-7-deazaguanine synthase n=12 Tax=Firmicutes TaxID=1239 RepID=A0A0G3WEL0_9CLOT  ali  22  2................LKVNEIFLSIQGEGISTGYPTVFLRLSGCNLRCLYCDTSYSY---------------EDGEEMTMEEVLEKVTSY-----GYKRVCLTGGEPLLQQEIKTLLTALKE-YEINIETNGSVDILGEKHRFTMDIKTPSSGENNCLSNFKYLRENDEIKIVIGDHQDYLWAIITFSPIYNRVDPKKIVQWMLEDGIDARFQLQLHKILWDP 205
39 3.000e-53UniRef50_A0A257A1C9 7-carboxy-7-deazaguanine synthase n=1 Tax=Euryarchaeota archaeon ex4484_162 TaxID=1978125 RepID=A0A257A1C9_9EURY  ali  24  1................MKINEIFYSIQGEGKLSGYPTIFIRLTGCNLRCRYCDTKYAY---------------YDGIETSLNDIFSRIKSY-----PCRNVCITGGEPLLQKETPLIKKLVDKKYRVFLETNGSIDLSDVVKIISLDIKCPSSGMQDKMENINYLSEKDQLKFVISNREDYEYSKDVMDRFKPNCEIFRLARWILEDGLNVRISLQLHKI.... 204
40 4.000e-53UniRef50_Q2IQJ3 7-carboxy-7-deazaguanine synthase n=5 Tax=Deltaproteobacteria TaxID=28221 RepID=Q2IQJ3_ANADE  ali  31  1................MRVTEIFFSIQGEGSRAGRPCVFVRFTGCDLRCGYCDTAYA---------------FHGGVDMDRAAVLAEVAR-----HPARFVCLTGGEPMLQRELPLARDLVARGYEVAVETHGQRPLDALPAIRVVDVKTPGSGEVTDFAYLDRLQPHDEVKFVVCSEDDFRWSREVVRRHALEGRVQDLVRWMLESGLDARLSLQVHKVIWGP 205
41 4.000e-53UniRef50_A0A1D9FS23 7-carboxy-7-deazaguanine synthase n=2 Tax=Clostridiales TaxID=186802 RepID=A0A1D9FS23_9CLOT  ali  23  1................MKVNEIFLSIQGEGISTGYPTVFLRLAGCNLRCRYCDTSYSYA---------------EGEEMTVEEVFKKVTSY-----GYKRVCLTGGEPLLQQEIKILLAALKE-YEINIETNGSVDILGENHRFTMDIKTPSSGESNCLSNFKYLREKDEIKIVLGDYQDYLWAIITFSPIYNRIDPKKIVQWMLEDRIDARFQLQLHKILWHP 204
42 6.000e-53UniRef50_A0A0C7NKP8 7-carboxy-7-deazaguanine synthase n=7 Tax=Bacteria TaxID=2 RepID=A0A0C7NKP8_9THEO  ali  27  1................MLVKEIFLSLQGESTGAGLPTVFVRFSGCNLRCRYCDTKYAY---------------EGGEEVSVQALFERIS-----QYPYRRVCLTGGEPLLQSREELQLLNVLSNYEVSIETNGSLPLLNPDQRWVMDIKCPGSGAANRWENLSLIRPEDEIKFVVSSEDDYIWARLLFSPAYGLLEPACLAEWILSDGLDVRLQLQLHKIIFGP 208
43 6.000e-53UniRef50_F8ACX8 7-carboxy-7-deazaguanine synthase n=6 Tax=Bacteria TaxID=2 RepID=F8ACX8_THEID  ali  24  2..........PERDLILDIAEIFVSLQGESTYVGLPTFFVRLAGCNLQCQWCDTVYAQQPQ--------------KNFISLSEILDR----WQRGGKLKVVQITGGEPLLQENVPLMKAFLDKGATVLLETNGSMPLERVPREVIMDIKPPSSEMNARFENLAYLDRKDQVKFVIADREDYKWAKVLFSPVWQRLEPRELAEWIIKDKLPVRFQLQLHKILW.. 213
44 9.000e-53UniRef50_A5CX03 7-carboxy-7-deazaguanine synthase n=21 Tax=root TaxID=1 RepID=A5CX03_VESOH  ali  22  5...............KLNINEIFYSIQGEAREVGLPSVFIRLTGCPLKCTYCDTEYA---------------FHGNNLMEIDAIISEIK-----QYDTTYICVTGGEPLLQKNCYLLLRLVENNYQVSLETSGSINIQDVNALVSMDVKTPSSGESEKYTNFKKLTVKDQLKFVIGSHSDFDWSVAILNQYHTTAGVLQLADWILDQQLNVRLQLQLHKLLW.. 207
45 1.000e-52UniRef50_A0A2V9DFF1 7-carboxy-7-deazaguanine synthase n=7 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9DFF1_9BACT  ali  28  1................MVITEIFKSIQGESTYAGLPCVFVRLTGCNLRCTWCDTAYA---------------FYGGTKMSVGEVLARVRELSPARPAIPLVELTGGEPLLQPDVPLADKLLAAGYTVLIETSGERYVGKLPREVIVDVKCPDSGEADTFDNLDAVDRKDEIKFVISSRRDYEFVVNDPEGSWPGMSARELSEWILADGLPVRLGLQLHKFIWDP 244
46 1.000e-52UniRef50_I3INJ2 7-carboxy-7-deazaguanine synthase n=6 Tax=Planctomycetes TaxID=203682 RepID=I3INJ2_9BACT  ali  20  1................MKINEIFKSIQGETSYAGLPCTFIRITGCNLRCRYCDTTYAY---------------EDGVEMSMNSILESIHDFSSN-----LVCITGGEPLSNEDTPLIQRLLDKNYTVLVETNGSYDIIPEKAVTIMDIKCPGSTMSMHWQNIAYLRQSDEVKFVLASRDDYKWTKDVIQKYNLSEIAKVLVQWILEDNLKVRFQLQLHKYIWEP 206
47 2.000e-52UniRef50_F8C2N1 7-carboxy-7-deazaguanine synthase n=14 Tax=Bacteria TaxID=2 RepID=F8C2N1_THEGP  ali  23  3...............KLKISEIFFSLQGEGPLIGYPTLFVRLFGCNLNCSWCDTPYA----------------KGENPYEEKEISEIISFWKKNFSSIPFITITGGEPLIQSSVYLIDAFLKLGCTIALETNGSISLDKVPKEVIMDVKTPSSKMYNLYENFKFLTKKDAVKFVIKDREDFDFAIDIVEKFYLTLDPKILANWILETKKPIRFQIQLHKIVGI. 212
48 2.000e-52UniRef50_A0A1Z8SQI4 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A1Z8SQI4_9BACT  ali  22  1.......MVGRSGGTGLRVVEIYPSIQGESTRAGLPCVFIRLAGCPLRCRWCDTVYS---------------FKGGDEMSLEEICDAAAE-----PGISLVELTGGEPLAHSEAPLLKMLCDRFTEVLLETSGAFPIGDLDPRVIMDLKAPGSGEEDRLENLDHLKSGDELKLVLADREDYEWAKILFSPVHGELDPALLSDWILEDKLAVRLQLQQHKFIWDP 213
49 3.000e-52UniRef50_A0A0D6E8A0 7-carboxy-7-deazaguanine synthase n=10 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A0D6E8A0_9GAMM  ali  58  2................YQVKEAFYTLQGEGAQAGRASVFCRFSGCNLWSGREVDRATAKCTFCDTDFIGTNGINGGKFATAAALAEHIAALWPSQSATPYVVFTGGEPLLQLDAPLIATLHSHGFEVAVETNGTLPPPPGIDWLCVSPKGSNPLVVTQGDELKLVYPQADAPPEQFSRLGFHHFFLQPMDLNQAKTTVAEATAYCMANPQWRLSLQMHKLAG.. 212
50 3.000e-52UniRef50_Q1Q0J9 7-carboxy-7-deazaguanine synthase n=34 Tax=Bacteria TaxID=2 RepID=Q1Q0J9_KUEST  ali  23  1................MLINEIFRSIQGETSFTGLPFVFVRLTGCNLRCSYCDTQYAYD---------------EGNEMPISSIIDKIDSF-----GLKSVCVTGGEPLSNHNTPLVRELLNRNYTVLVETNGSYDVLPEGTIRILDVKCPDSGMSHKWHNISHLTKKDEVKFVLSSRNDYEWARSMISKYHLTEIAHILASWILEDHINVRLQLQMHKYIWGP 206
51 3.000e-52UniRef50_A0A2M7TR95 7-carboxy-7-deazaguanine synthase n=2 Tax=cellular organisms TaxID=131567 RepID=A0A2M7TR95_9BACT  ali  20  1................MKINEIFLSIQGEGVQTGLPTFFIRTKGCNLRCNYCDTKYAY---------------TKGHDMTLNEIVKEV-----RKQPYKLVCLTGGEPLIQPIASLIEKLVQENYKVCIETNGSINISKFPNLYSLDIKCPSSSMTDKMKNLNYLKKKDQIKFVMRTQKDYEFAKSIVKRYKLSNKARWIVDKVLSDKLNVRIGLQIHKIIW.. 205
52 4.000e-52UniRef50_Q0VRI9 7-carboxy-7-deazaguanine synthase n=149 Tax=Bacteria TaxID=2 RepID=Q0VRI9_ALCBS  ali  21  1..............MELRLTEIFHSLQGESRTVGRPTVFVRLTGCPQRCVWCDTEYA---------------FSGGEKWSLAAILEEVAAL-----GAQYVTVTGGEPLAQPCLPLLKTLCDEGYQVSLETGGAMDIAGVDERVSMDLKAPGSGENNRLSNIALLKAHHQVKFVLADRKDYDWARFMLDQYQLHQRVSDLANWIVEDRLPVRFQLQLHKLLW.. 207
53 5.000e-52UniRef50_Q89ZC3 7-carboxy-7-deazaguanine synthase n=51 Tax=Bacteria TaxID=2 RepID=QUEE_BACTN  ali  44  1..............MMRKINEIFYSLQGEGYHTGTPAVFIRFSGCNLKCSFCDTQH-----------------EAGTLMTDDEIIAEVSKY-----PAVTVILTGGEPSLWIDDALIDRLHEAGKYVCIETNGTRPLPESIDWVTCSPKQGVKLGITRMDEVKVVYEGQDIS--IYELLPAEHFFLQPCSCN----NTALTVDCVMRHPKWRLSLQTHKLIDI. 181
54 6.000e-52UniRef50_A0A095ZKY7 7-carboxy-7-deazaguanine synthase n=7 Tax=Bacteroidales TaxID=171549 RepID=A0A095ZKY7_9BACT  ali  35  3...............SYKINEIFYSLQGEGRWAGRAALFVRFSKCNLACPFCDTDFA-----------------AYRELSGADIVAAL----GRHPLCRFVVLTGGEPTLQVDPELLRRLHERGYYVAMETNGTNPILEGVDWVTCSPKAAVKGGLPRVGAVDELKVFDGRHEVSDFGIEAAARYVQPCDMGDARRNKAILAEFVKDHPEWQLSLQQHKLIGI. 194
55 7.000e-52UniRef50_A0A256XMA7 7-carboxy-7-deazaguanine synthase n=1 Tax=Thermoplasmatales archaeon ex4572_165 TaxID=2012525 RepID=A0A256XMA7_9EURY  ali  23  3...............SLLINEIFYSIQGEGKWMGLPNIFIRTTGCNLRCSYCDTTYAY---------------KNGEEKSLEEILEEISKFYCKK-----ICVTGGEPLIQDNIELFTLLIDNGYLLCLETNGSKSVEPYLEYFSLDIKCPSSEMHENISNLKMLRPIDQIKCIIGDRKDYEYAKQILSDNNISCNVFTISNWVLEDNLPYYVGIQLHKYIW.. 206
56 7.000e-52UniRef50_A0A259GL51 7-carboxy-7-deazaguanine synthase n=4 Tax=unclassified Hydrogenophilales TaxID=1798413 RepID=A0A259GL51_9PROT  ali  26  219.SPSGRAEVSMSDALTLRLTEVFLSLQGETSRAGLPTVFVRLTGCPLRCRWCDTPYS---------------FQGGETVTLPSLLAQIAAL-----GVSTVCVTGGEPLAQKNCPLLTALCDAGYSVSLETSGALDVSQVDPRVIVDIKAPESGARNRWENLVHLTPNDEIKFVLANRADYDWAREVISPVQGELPPAQLADWVLADRLPVRMQLQLHKILW.. 437
57 7.000e-52UniRef50_K0NML0 7-carboxy-7-deazaguanine synthase n=8 Tax=Desulfobacterales TaxID=213118 RepID=K0NML0_DESTT  ali  23  1..............MQLNICEIFYSLQGESSFTGLPCIFIRLSGCNLACSWCDTEYANTESH---------------PMTIDQILK-----KTLSYNCNLVEITGGEPLLQDGTPLISALLDKNYQVLLETNGSKSIISLDCIKIMDIKCPSSNESDSFENINFLTQQDEIKFVISSRKDYEFRKISPKKIHLSPSPDAIAGWMIDDNLHARLSLQQHKIIWDP 209
58 7.000e-52UniRef50_A0A0A7LAD7 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Methanoplasma termitum TaxID=1577791 RepID=A0A0A7LAD7_9EURY  ali  27  1................MKICEYFGSIQGEGITIGIPTYFIRTAGCNLRCEWCDTAYAW---------------EGGMETSVDEIMEIVDD-------TENVCVTGGEPLLQKDMPLIDRLLEAGKRIVIETNGSKDIIPKNDIISMDVKCPSSGMSDKNSNLRYLGKKDQIKFVIGNHVDLNYAIRFIRENPGGMDLLHIAEEVINRKLNVRVLPQLHKIIW.. 201
59 8.000e-52UniRef50_A0A0J6NHF2 7-carboxy-7-deazaguanine synthase n=17 Tax=Proteobacteria TaxID=1224 RepID=A0A0J6NHF2_9NEIS  ali  57  3...............TYTVKEIFYTLQGEGRQAGRAAVFCRFAGCNLWSGREEDRAKAVCQFCDTDFVGVGPDGGKFKSAAALAERIAAEWPAGAGGTPYVVCTGGEPLLQLDAELIAALHRLGFEVAVETNGTMAAPPGLDWICVSPKAGAELLLRSGDELKLVYPQATQLPETVEQLDFDTFYLQPMDGPDLAANTRAAIAYCMAHPRWRLSVQTHKVTNI. 210
60 1.000e-51UniRef50_A0A1G3QFD3 7-carboxy-7-deazaguanine synthase n=6 Tax=Bacteria TaxID=2 RepID=A0A1G3QFD3_9SPIR  ali  25  1..............MTLTVNEIFYSIQGETCSAGLPSVFVRLTGCNLDCSYCDTPCA---------------REDGTSLEIDSIIQKIEQY----PSADHVTLTGGEPLLQTNAILLRQIIDRGWKCQIETNGSILLKDVPEKVIVDVKTPSSGESDEMRNLKYLTDRDEVKFLISSIEDYDFLVINFSPVYNTMPYAELADRIINDKLAVRLNLQLHKIIWGP 209
61 1.000e-51UniRef50_A0A1V5YYU0 7-carboxy-7-deazaguanine synthase n=12 Tax=Bacteria TaxID=2 RepID=A0A1V5YYU0_9BACT  ali  23  29........PKEELLMSLLISEIFASIQGESSRAGLPCIFIRLAGCNLKCRWCDTTYA---------------KEGGSEKSINTILEAVGSWKIR-----LVEITGGEPLYQPECSLAQQLLQAGYTVLVETNGSQPIAQLPDGVIMDIKCPDSGMADHFANVEALTEEDEIKFVLASRRDYEYGVAMIRQYRLDQRCRQLAEWMLADLPPARLHLQLHTVIW.. 241
62 1.000e-51UniRef50_A0A1Q4GU49 7-carboxy-7-deazaguanine synthase n=4 Tax=Proteobacteria TaxID=1224 RepID=A0A1Q4GU49_9PROT  ali  26  2................LRVTEVFLSLQGETSRAGLPTVFVRLTGCPLRCRWCDTPYS---------------FQGGESATLPALLARIADY-----GVSTVCVTGGEPLAQKHLALLTALADAGYSVSLETSGALDIAGVDPRVIVDIKPPGSGEVNRWENLALLTPHDEIKFVLAGRADYEWARDVLREEALDRRCEQLAAWILQDRLPVRMQVQLHKILW.. 205
63 2.000e-51UniRef50_A0A1G0Z9W1 7-carboxy-7-deazaguanine synthase n=9 Tax=Bacteria TaxID=2 RepID=A0A1G0Z9W1_9BACT  ali  26  8..............PRITVTETFSSIQGESTYAGCLCFFIRLAGCNLNCNYCDTLYSRKTSH-------------GKSTDIPLLVEAALKE-----NINLVEITGGEPLFQKTTPLLCAELLRNFTVLVETNGSLPILPENVIKIMDCKTPSSGEASKMDNFDLLNPIDEIKFVIADRTDYNYSLDIIEKYKLNEESAELAGWIIKDKAPVRLQLQLHKYIWGP 218
64 2.000e-51UniRef50_A0A238Z5C9 7-carboxy-7-deazaguanine synthase n=3 Tax=Bacteria TaxID=2 RepID=A0A238Z5C9_9DELT  ali  29  1..............MSLRICEIFKSIQGESTFAGRPCVFVRLVGCNLRCAWCDTAYS---------------HEGGEDLSAEAVLARIDAL-GGGLPHMLVEFTGGEPLLQPEVALANRLARDGRTVLVETNGSLDISALHPDVAVDMKGPSSGESAKMDNLERLRARDEVKFVIADRLDWERMLCLLPPVPGILAAADLARWMLDADLDARLNLQLHKHIW.. 209
65 2.000e-51UniRef50_A2STX3 7-carboxy-7-deazaguanine synthase n=8 Tax=Methanomicrobiales TaxID=2191 RepID=A2STX3_METLZ  ali  26  1................MRVTETFVSLQGEGERQGMPCFFLRLSGCNLRCAWCDTEYS---------------FEKGTDRSVDELVKEIAD-----SGLSYVCVTGGEPLLQKLIPLLEILAAADIHVDIETNGTIPFDDVSAYICMDVKCPSSGEMSDLSLLSALTENDCVKFVIGDEADYLYMVEVLAAHKPKADTKWLVETIIAERLPVRFQLQLHKVVNV. 201
66 2.000e-51UniRef50_UPI00025AE564 7-carboxy-7-deazaguanine synthase n=1 Tax=Mycobacterium phlei TaxID=1771 RepID=UPI00025AE564  ali  49  1..............MTYFVNEIFYTLQGEGYWTGRPAVFCRFSRCNLWTGKEEDRHRAICSFCDTD------FSDYTEYTHYELARVIKDLWP-GGGEPMVVFTGGEPALQLDFTLVK--HLRGWYTAVETNGTVLLEAPVNWVCVSPKTPRVRITAG-DELKLVYPQERITPNLFENLSFRHFWISPMDGPSLAENTAAAVEFVKANPKWRLNTQVHKTIGIP 200
67 4.000e-51UniRef50_A0A1F9WXN6 7-carboxy-7-deazaguanine synthase n=1 Tax=Elusimicrobia bacterium RIFOXYA2_FULL_39_19 TaxID=1797957 RepID=A0A1F9WXN6_9BACT  ali  24  2................LKINSIYKSIQGESNYTGLPCVFIRLAGCNLRCSYCDTKYAY---------------NKGRAVTIPAILTRVKAL-----GCHLVQVTGGEPLLQQDTPLINELIKQGYKTLLGTNGTYPILNKKCVKLMDIKCPSSKAGANPGNLKHLTNHDEVKFVISNAADYNYAKTMLKKHSLTKNPKVLASWILKDNLSVKLGLQIHKYIW.. 205
68 5.000e-51UniRef50_V5DZE9 7-carboxy-7-deazaguanine synthase n=9 Tax=Proteobacteria TaxID=1224 RepID=V5DZE9_9GAMM  ali  22  3...............SVRITEIFFSLQGESNTVGIPTVFIRLTGCPLRCGYCDTEYA---------------FTGGQKKSISDIIAEVESF-----GSRYITVTGGEPLAQPCLELMTKLLDLGYVVSLETSGALDISGVDSRAVMDIKTPSSGELSRFSNIRHLNKNDQVKFVIGNDEDYTWSKRILSEYQLADRCTELADKILQDKLPVRFQIQLHKLLWD. 208
69 5.000e-51UniRef50_G2LFE7 7-carboxy-7-deazaguanine synthase n=42 Tax=Bacteria TaxID=2 RepID=G2LFE7_CHLTF  ali  22  1................MRITEIFFSIQGESSYAGLPCAFVRTTGCDLRCTWCDSEYT---------------FTGGTHMSVEEILERIRAY-----PTRLVELTGGEPLLQKDIELAGRLLDEGYTVLIETGGHRDVSRLDPRIIMDIKCPGSGMKNLWSNLDHITRRDEVKFVLADLADYFWAREILRIYRLEQEQRPIVERLLADGLQVRFQTQLHKLIW.. 203
70 6.000e-51UniRef50_A0A1V5UNG9 7-carboxy-7-deazaguanine synthase n=9 Tax=Bacteria TaxID=2 RepID=A0A1V5UNG9_9BACT  ali  20  1.......MPNDSSILKFKVNEIFKSVQGESSYAGLACAFVRLSGCNLRCAYCDTVYAY---------------KYGRYLTAGEIISKVDALDP-----HIIELTGGEPLMQDLLVEYLNNKKKGRRLLIETSGSISIKGLNDVIIMDVKTPSSGSSMIFDNFNHLKSVDEIKFVIGDRADYEYCKNIIFEYSLAEKCEKIIKWMLQDGVKARFQLQMHKYIW.. 226
71 6.000e-51UniRef50_A0A120MIB5 7-carboxy-7-deazaguanine synthase n=4 Tax=Euryarchaeota TaxID=28890 RepID=A0A120MIB5_9EURY  ali  23  1................MRIVETFLSIQGEGLMIGRLTFFIRAAGCNLRCAWCDTKFSLD-------------HKAGTDMTVDQLIEAV-------GSTENVCFTGGEPLEQPDAELLQRLVDAGKTVVLETNGSKDLSDVPIIISMDIKCPSSGMQDRMSNLGILSKKDQLKFVISDRTDLIYATNVIFSPVGGMDLGFLAEEVVSKKLDVRVLPQLHKIIW.. 203
72 7.000e-51UniRef50_A0A2D4TNT5 7-carboxy-7-deazaguanine synthase n=4 Tax=Bacteria TaxID=2 RepID=A0A2D4TNT5_9DELT  ali  20  9...............TIMVHEIYLSIQGETSHSGVPCVFVRTQGCSLRCSWCDTVYALDFKNRHM------GKWLAKPYTLYQVLEEVKRL-----GVQTVEVTGGEPLDQPAAPLLEALCEEGYTVLLETAGHKPIEHLDVHVIMDMKCPSSGMSKHMQNILHLKKKDEVKFVVECREDYEWAKKMIDEYENKIDSKRMXSWMLQDKLKARFQLQIHKHIWD. 223
73 8.000e-51UniRef50_A0A2E5J7A0 7-carboxy-7-deazaguanine synthase n=11 Tax=cellular organisms TaxID=131567 RepID=A0A2E5J7A0_9RICK  ali  47  2................FKVKEIFSSIQGEGYYTGRPAVFVRFTGCNLWNGKLKNKQNALCNFCDTDFVGTDGLNGG-DFSLNQLSTKVEEVWKYKTLQKFVVLTGGEPMLQANSRLVERLKQKGFFVALETNGTIAIDINFDWVCVSPKNLNLWKVKKGDELKIIYPQQRFDLNSLKRLNFKYFFLQPLDDNKKQINIIKTIEYCKSHKPWFPSFQIHKTLNI. 209
74 9.000e-51UniRef50_D8JEE1 7-carboxy-7-deazaguanine synthase n=313 Tax=root TaxID=1 RepID=D8JEE1_ACISD  ali  23  1MASLRSSAIPVSDPASLRITEIFYSLQGEANASGLPTVFIRLTGCPLRCSYCDTTYS---------------FEGGERFSLEHIIETATQYQT-----PYICVTGGEPLAQPNLILLQRLCEAGFDVSLETSGALDVSKVDSRVSLDLKTPTSGEENLISNLDHLTAHDQIKFVICNREDYEWSKQQVEKYQLHKKVRDLAQWILDDKLLVRFQLQLHKLLW.. 230
75 1.000e-50UniRef50_B0VFJ6 7-carboxy-7-deazaguanine synthase n=4 Tax=Bacteria TaxID=2 RepID=B0VFJ6_CLOAI  ali  25  5................LNVTEIFYSLQGESAYSGYPCIFIRLSECNLRCVYCDTQYA---------------FGKGKSMAISSIMEEVKKY-----PCSLTEITGGEPLLQEDVDLFEELHKSSYKILLETNGAISLEKVPDYVIVDVKTPGSGMVDAFDNLDYLNDKDELKFVLTDKNDYQFAIIHFSPLTEVLEPKELAKWMLKDGIKAKLTLQLHKIIGI. 208
76 1.000e-50UniRef50_A0A1V4T9P5 7-carboxy-7-deazaguanine synthase n=6 Tax=Euryarchaeota TaxID=28890 RepID=A0A1V4T9P5_9EURY  ali  27  1................MLVNEIFLSIQGEGLTMGLPTVFVRLSGCNLDCSWCDTRYA---------------GEGGIEMDAPRVLDSV-----RGYRVRHVCITGGEPLLQKERELISLLLDAGKVVVLETNGSLSLEGLPDRISMDYKCPSSGQEARMGNLALLGPKDQLKFVVADKEDLEPRCPVILTPVGGLTLEPVVRFVLDRGLEVRVLPQLHKIIW.. 203
77 2.000e-50UniRef50_H8N156 7-carboxy-7-deazaguanine synthase n=50 Tax=Bacteria TaxID=2 RepID=H8N156_CORCM  ali  23  9MPAARPHIEPRRTADSVVVKELYLSLQGESSHAGMLCGFIRLTGCHLRCTYCDSEFA---------------FHGGSRMKIPEVVEKALAW-----NTPTVEVTGGEPLLQPGVPLMEALLDAGLKVLLETSGAIDVVPPAVHKIVDMKTPSSGECDRNDYRNLMNANDELKIVIGSRVDYEWARALVTEHQLGKKPRQLAEWIIEDRLPVRFQLQMHKYLWDP 233
78 2.000e-50UniRef50_F0R8U1 7-carboxy-7-deazaguanine synthase n=16 Tax=Bacteroidales TaxID=171549 RepID=F0R8U1_BACSH  ali  43  3.................KINEIFYSLQGEGAHAGTPAVFVRFSGCNLKCIFCDTSH-----------------ESGTEMGDEEIIEEVCKY-----PCRMVIMTGGEPGLWIDDALVDLLHKAGKYVAVETNGTQVLPEAVDWVTCSPKEGTVLRVRHIDEVKVVYIGQDVSLLIEAKEHF----LQPCSCQNTEEVIE----YIKKHPQWRLSLQTHKLINIP 181
79 2.000e-50UniRef50_T1CVL3 Radical activating enzyme n=1 Tax=mine drainage metagenome TaxID=410659 RepID=T1CVL3_9ZZZZ  ali  24  1................MRLIEIFHSIQGEGPLTGRRTSFIRTARCNLRCSWCDTTYS---------------FGPGKERSIASILKEIER-----HRTPYVCLTGGEPLLQPEAALLRELARRGKTTVVETGGSLDVTPYLVILSVDVKCPGSKMENRWSNLALLRPTDIVKFVLRDRRDYLYAKRVIARHPLPKEVVRLADWVLADRLNVRVLLQEHKVLW.. 203
80 2.000e-50UniRef50_A0A2E0I7Q4 7-carboxy-7-deazaguanine synthase n=1 Tax=Nitrosomonadales bacterium TaxID=2026761 RepID=A0A2E0I7Q4_9PROT  ali  22  10...............QLKVNEIFYSLQGESSYVGIPTIFIRLTGCPMRCGYCDTAYA---------------FIEGKNFTINQIVENISKYKT-----KNITVTGGEPLAQKECWLLKILSDRGYIVSLETGGAISINKIDDRVILDIKTPGSGKNNLWSNLKLIKPKDEIKFVITDLDDYIWAKILFSPVYGNIKPKDLAEWILNDHLPVRFQIQLHKMIWIP 218
81 2.000e-50UniRef50_A0A1F7FL05 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A1F7FL05_9BACT  ali  25  1..............MDLVVSEIFVSLQGESSEAGRRCAFVRLAGCNLDCAYCDTRYA---------------RTGGKKMTLAQVITAVEKL-----NCPLVEVTGGEPLHQPKVDLMKALLKKGHEVLLETNGSCDLSPVPRRIIMDIKTPSSNMYNMLSNIRLLKRTDEIKFVITDKRDYSFSRQIIKKYKLDKKCQHLAQWILNDKLNVRLNLQLHKIVW.. 206
82 3.000e-50UniRef50_D6YWT8 7-carboxy-7-deazaguanine synthase n=8 Tax=Parachlamydiales TaxID=1963360 RepID=D6YWT8_WADCW  ali  20  1MVNSIAMMIERTNNQTLRLIEIFLSIQGETSLTGLPTTFIRLASCNLRCTWCDTPYS---------------FGKGESSSLQSIIETV-----RSNGASHVCITGGEPLLQSQVYLLMETCNLDYIVSLETGGSLSTEKVDPRVILDIKCPGSGMKNTWENLERLREQDEVKFVIMNREDYEWSVPLFSPVHNVLNPQELIQWTLQDTLPVRINLQVHKWVWSP 223
83 3.000e-50UniRef50_A0A1J5DJ35 7-carboxy-7-deazaguanine synthase n=3 Tax=Deltaproteobacteria TaxID=28221 RepID=A0A1J5DJ35_9DELT  ali  33  1................MKVNEIFYSVQGEGKNSGIPMVFVRLAGCNLRCDFCDTKYA---------------FEAGKEMMVGEILSE-----RGKYPSKWVCITGGEPFIQPLDELARQLKADGSLIQIETNGTIFQPVTCDWLVVSPK------KERRPVESMLERANEIKIVVNLKEALDFTCHSIQPENNHEEATKLCLDFVAEHPQWRLSMQLHKLINI. 189
84 3.000e-50UniRef50_Q1IHK7 7-carboxy-7-deazaguanine synthase n=14 Tax=Acidobacteriales TaxID=204433 RepID=QUEE_KORVE  ali  26  1................MQITEIYRSLQGESSYTGIPCIFVRLTACNLRCAWCDSEYT---------------FKGGRKMSEDEIFAEVQKLA----PGGLVEITGGEPLLQELVPFMERLVASGYKVLIETSGERPLANVPDVVIVDVKCPASGESFRIENLDALTPHDEIKFVISDRADYEFARVIFSPAFRKDDPQDLANWVLEDQLDVRLGLQTHKFIWTP 221
85 3.000e-50UniRef50_B5YGD1 7-carboxy-7-deazaguanine synthase n=44 Tax=Bacteria TaxID=2 RepID=B5YGD1_THEYD  ali  24  1................MKVCEIFTSIQGESSLAGIPMVFVRLTGCNLRCSYCDTKYAY---------------YEGEELSINKVLEKI-----HSFPFQYVEITGGEPLLQDETYKLINELVKSHNVLIETNGSIPIEKVNVKIIMDIKTPGSGMSEKIENLRFLKKIDEVKFVLTNRDDYEWAKNFIKNHEIKANEIELAKWLINDGISVRLNLQIHKYI... 201
86 5.000e-50UniRef50_D5VAC7 7-carboxy-7-deazaguanine synthase n=995 Tax=root TaxID=1 RepID=D5VAC7_MORCB  ali  22  36....NTKIPTTDPQAGLKLTEIFYSLQGEALTAGLPTIFIRLTGCPLRCHYCDTTYS---------------FSGGERWGLDDIMTHIA-----QYPCWRVCVTGGEPLAQPNAILMHKLIQSGYEVSLETAGALSVANVPPLVSMDLKSPSSGEKNLWENLAHLTLHDQIKIVIANRTDYEWAKNIITKHALDDKVTDLAEWILKDALPVRFGLQLHKIIW.. 260
87 5.000e-50UniRef50_A0A2A5AK26 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Cloacimonetes bacterium TaxID=2030808 RepID=A0A2A5AK26_9BACT  ali  24  6................IKINEIFYSIQGESTHAGRPCIFIRTSGCKLRCSWCDTKYSYD---------------EGENYTFEKLLKEIKKF-----DCNLVELTGGEPLEQNSFLFLQILLDRGYEVLLETGGHCSLEKVPSKIIVDIKCPASLMHKDWDNLAFLNSKDELKFVIQDRNDFDWAIDIIKKYSLKGKNEELAKWICDEAPFARFQMQFHKIIWD. 210
88 6.000e-50UniRef50_A0A2E8Q0N1 7-carboxy-7-deazaguanine synthase n=1 Tax=Nitrospinae bacterium TaxID=2026769 RepID=A0A2E8Q0N1_9BACT  ali  23  17...............TLKVNEIFKSIQGESTYSGLPCAFIRLTGCNLRCDYCDTTYAYD---------------KGREFLINDLLKEIEKL-----NCNLVEVTGGEPLLQKNFGLFDQLVSKNYFVLLETNGTVSLKNVNPSVIMDIKCPGXGFNTDWRNLEYLSSKDQIKFVISSRGDFDWAVKVIKEKDLEKKSKDLANWILEENINARFQLQLHKY.... 219
89 8.000e-50UniRef50_I0JYJ2 7-carboxy-7-deazaguanine synthase n=239 Tax=root TaxID=1 RepID=I0JYJ2_METFB  ali  22  1MDDITFLPREEVFKLKLVVNELFLSIQGESTFAGYPCAFIRLTGCNLRCRWCDTTYA---------------FSEGKLLPIEAIINQIQKF-----NIPLVEVTGGEPLLQKNLHLLRLLCDLGYQVLLETSGALSIRQVDPRVIVDLKCPSSGESEKLANLDWLREKDELKFVIGNNEDYQWAKTKLKE--EKERLTKLSEWILADRLNVRLGLQIHKYIWHP 224
90 1.000e-49UniRef50_A0A1Y4U3G2 7-carboxy-7-deazaguanine synthase n=12 Tax=Bacteroidetes TaxID=976 RepID=A0A1Y4U3G2_9BACT  ali  28  1MAVTTDPALFDGGRM-LPLVEDFYTIQGEGFHAGKPAYFIRLGGCDVGCRWCDAKYTWNP----------------KLYPPTDVRTVIERATSC--PAQAIVITGGEPLLYPLGVLTDELRKKGLEIFLETSGSHPFSGVFDWVCLSPKPPLDEAYGRA---------DELKVIIESEADLEWALYLQPEWSRSEEVMPLLVEYAKAHPRWNISIQTHKYMHIP 211
91 1.000e-49UniRef50_M1PDU7 7-carboxy-7-deazaguanine synthase n=8 Tax=Bacteria TaxID=2 RepID=M1PDU7_DESSD  ali  22  5................IKISEIFYSIQGESSYAGLPCIFIRLSGCNLRCNYCDAAYTW---------------EEGDPWSIDSILAKV-----NSYPCDLVEVTGGEPLLQKNCPELLAGLSQGKKTLLETNGSIAINAIPDIAILDVKCPDSGSKDSFHPDNLLLIRAELKFVLSTQDDYIWAKILFSPVQPGVTAQDLADWILKDGLDVRLQIQLHTILW.. 215
92 1.000e-49UniRef50_I0IKD8 7-carboxy-7-deazaguanine synthase n=2 Tax=Leptospirillum TaxID=179 RepID=I0IKD8_LEPFC  ali  22  1................MKITELFRSIQGESLYSGWPCFFIRTSGCPLRCTWCDTTYS---------------FYGGTDMTVDEIL-----LETGKSETNLVEITGGEPFVQTDFELSNRLRREGYEVLIETSGGFPIPEGLDRVIMDIKPPGSGMSQWMDHFRSLTSNDEIKAVCQSREDFDWVVVTVSPVFDLVDPKELGQWVLESRRRFRIQIQLHKILFDP 207
93 1.000e-49UniRef50_Q31NK7 7-carboxy-7-deazaguanine synthase n=231 Tax=cellular organisms TaxID=131567 RepID=Q31NK7_SYNE7  ali  28  11...............TLPIVETFHSVQGEGAWMGCSAFFIRLAGCDVGCPWCDTKQSWPRDRHP-------------EVAIADLVEAAVAAQPQF-----VVITGGEPLLHDLTELTNALRSQGLRCHLETSGSASPSGSFDWVTLSPK-PFKAVVAANYNWAN-----ELKVVIQTDADFDFAKLLQPEWNSPESC-DRVVNYVRQHPRWRVSLQTHKFLGV. 205
94 2.000e-49UniRef50_S8FD96 7-carboxy-7-deazaguanine synthase n=9 Tax=Bacteroidetes TaxID=976 RepID=S8FD96_9BACT  ali  39  1..............MK-KINEIFYSLQGEGFYTGTPAVFIRFSGCNLRCAFCDTRH-----------------EEGSMMSDRAILREVMK-----HPAKMVILTGGEPGLWVDENLVEQLHALGKYVCIETNGMYALPANIDWVTCSPKREGELRLKRMDEVKVVYLGQDVSIYLQ--LPAKHFFLQPCSGKNTVEVLG----YILKHPDWRLSLQLHKLLNI. 180
95 2.000e-49UniRef50_A0A2H5W7C4 7-carboxy-7-deazaguanine synthase n=1 Tax=bacterium HR11 TaxID=2035406 RepID=A0A2H5W7C4_9BACT  ali  24  6................LQVTEIFYSIQGESTWMGLPCIFIRLTGCHLRCVYCDSEHA---------------FYGGVPMSYDEILEAIRRY-----PCRTVEITGGEPLLQKNIPLMELLLRQGYRVLLETSGALSIEPPPVIKVVDVKCPDSGAFPTFPNFRWLAPWDQLKFVIRSWRDFAWAVDFVREMDLIGRAKALARAILATGLPIRLQVQLHKYIHL. 210
96 2.000e-49UniRef50_A0A1W9VQX9 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Cloacimonetes bacterium 4572_65 TaxID=1972455 RepID=A0A1W9VQX9_9BACT  ali  22  2................IQLIEIFCSVQGESSYVGYPCIFIRLAECNLRCNYCDTKYSYIADY---------------SLSVEAIIEEVKRY----HPIKLVEITGGEPLLQKEVYLITQLERENFKVLLETNGSLPLDAVTVHKIVDVKCPDSGSKDSFSNLHTLNETDELKFVISSYDDYLWSKVLFSAVFEKVEPKVLVDWIIQDRLNVRFQLQIHKYIWNP 207
97 2.000e-49UniRef50_Q6MRN5 7-carboxy-7-deazaguanine synthase n=10 Tax=Bdellovibrionales TaxID=213481 RepID=Q6MRN5_BDEBA  ali  23  2................LKINEIFYSIQGETTYVGCPTVFVRLTACNLRCTYCDTKYSY---------------YEGEMQTLEAIIAEID-----SHKAPNVCITGGEPLLQKEVHLMKTLCDKGYLVSLETSGSKSVEMVDPRVILDVKTPDSGASFVMENIGFSTPSTEYKFVICSEKDFEWSEEFCRQHNLFEKFVWLAEKILQKNSSARLQLQLHKYIWNP 207
98 2.000e-49UniRef50_A0A2D4SFT4 7-carboxy-7-deazaguanine synthase n=5 Tax=Bacteria TaxID=2 RepID=A0A2D4SFT4_9GAMM  ali  25  1................MRVTEVFLSLQGEARAAGLPTVFVRLTGCPLRCHYCDTAYA---------------FHGGERQSVDSLLQRIRD-----HGVADVCVTGGEPLAQPGALLIRSLCDAGFSVAVETSGVLNIDRADRRAIMDLKTPASGELKRNDNIERLTGHDQVKFVVCDRADFDWACMQIREHGLTDEAAQLAEWLIDSRLPVRLQLQLHKQLW.. 204
99 2.000e-49UniRef50_UPI00048262A7 putative 7-carboxy-7-deazaguanine synthase QueE n=1 Tax=Desulfitibacter alkalitolerans TaxID=264641 RepID=UPI00048262A7  ali  25  2................LRVNEKFVSINGEGPHSGMLAVFIRFAGCNLQCSYCDT-----------QYAVNLTTAEYKEESVEDILSYIEEQ-----GIINIVLTGGEPLLQQLLMLIENLNARGYKVDIETNGSIDILPYKDIIIMDYKLPMSGMEEWMKNLQHLKNSDVVKFVCSTEKDLKKVKVFLSPVFGMLDPVAIVDYIKKRLNNVALQLQLHKILWDP 214
100 2.000e-49UniRef50_A0A2V9UVZ6 7-carboxy-7-deazaguanine synthase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9UVZ6_9BACT  ali  25  11....PRNTRSRQLPGSLTITEIYKSLQGESTHAGLACVFVRLTGCNLRCIWCDSEFS---------------FYGGKKMSRDEILDEVARLSPGGG---LVEVTGGEPMLQEREPLMEQLLDRGYKVLLETSGERALERVPASVIVDVKCPHSGEPDAIENLEALQPHDEMKFVLSNRADYEFARNFVGQHRLGNRVEELAQWILADEVPARLSLQIHKLIWDP 244
101 2.000e-49UniRef50_A0A2S0KU47 7-carboxy-7-deazaguanine synthase n=3 Tax=Lentisphaerae TaxID=256845 RepID=A0A2S0KU47_9BACT  ali  23  14.NPTTPPSPISRSSIAVRLVESFTSLQGESTHAGRICFFIRLAGCNLDCNYCDTRY-------------GRSFGAGEPASVDELVRRAQE-----SGTKLVEITGGEPLATPETPLCRRLLDAGFEVLLETNCSLPIIPREVRKILDCKLPGSGMAERNDNYALLAPHDEVKFVISCRADFDAMLEVIRRYDLPSKFTDLAEWVVSSRAPVRMQLQMHKLIW.. 235
102 2.000e-49UniRef50_A0A0S8G3M5 7-carboxy-7-deazaguanine synthase n=3 Tax=Proteobacteria TaxID=1224 RepID=A0A0S8G3M5_9PROT  ali  27  18...............RLRVNEIFFSLQGEARTVGFPTVFVRLTGCPLRCGYCDTEYA---------------FTEGRWMSFEEVEAAVAQYAPR-----HVTVTGGEPLAQPCRTLLKRLCDHGYEVSLETSGALDIIDARVSVVMDLKTPGSGEENRIENIALLKPKD-----------------QVSPVHGELSATELAEWILADRLPVRMQIQLHKYLW.. 192
103 2.000e-49UniRef50_K1XLJ3 Uncharacterized protein n=1 Tax=groundwater metagenome TaxID=717931 RepID=K1XLJ3_9ZZZZ  ali  20  4...............SLKLYEIFSSIQGESSFAGIPFTFIRLSGCPLRCRWCDTKYAY---------------NKGKIYTLNEILKIVEEI-----NLPHVMITGGEPLMQKNCAALIRILLKEFTVVVETSGAFSLKGLPRHYIVDVKTPSSGMSDKIHPHIFNKIIDEIKFVIANRNDYEFRKILMSTVFNKLKPQELARWIVDDKLNVRFQLQLHKYIWGP 209
104 3.000e-49UniRef50_A0A2E8SR53 7-carboxy-7-deazaguanine synthase n=18 Tax=Verrucomicrobia TaxID=74201 RepID=A0A2E8SR53_9BACT  ali  23  22................LRVHEIYLSLQGESTFAGLPCVFVRLTGCDLRCSYCDTAYA---------------FTGGEAISIESILDQVDALAEGYPEPPLVELTGGEPLLQKATPLLAALCDRGFTVLLETSGAHDISTVDTRVIVDLKCPSSGECDRTENIAHLRPSDEVKCVIGTREDYVWAKDQVPPEHTPLTRRELAEAITADRLPVRFQLQQHKHIW.. 246
105 3.000e-49UniRef50_A0A0F9B836 Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=A0A0F9B836_9ZZZZ  ali  23  1................MRIYSIFRSIDGEVYFQGCPTVFIRFAGCNLQCSYCDTKYAQD-------------IKVGKDMSVEEIVEEIKKY-----NIDKVTITGGEPLLQREDLNCLISKLRPIKITVETNGSIDLERYPDSWIVDYKLPSSGCMGKMKNFSNLRYNDFVKFVVEDKIDYAKALQVMDQIVSPEQPSELADWMIRDNIKAIFNLQIHKYIW.. 209
106 3.000e-49UniRef50_D3LT30 7-carboxy-7-deazaguanine synthase n=3 Tax=Veillonellaceae TaxID=31977 RepID=D3LT30_9FIRM  ali  24  4...............KLYVNELFNSIDGEGRRAGELASFIRLCGCNLRCSYCDTTYA---------------FTEGTPMAVEEILSQLQY--------RNITLTGGEPLLQDVHLLLQRLQDRD--VNIETNGSVSIRPYLVWFTVDYKSISSGMTTAMENFQLLRPQDVLKFVVGTHADLEIYISAVFAAIEPKEIVAYMEAY--RLMNWRLQLQLHKYIWPP 205
107 3.000e-49UniRef50_A0A1G1A9M1 7-carboxy-7-deazaguanine synthase n=1 Tax=Lentisphaerae bacterium RIFOXYA12_FULL_48_11 TaxID=1798578 RepID=A0A1G1A9M1_9BACT  ali  24  3...............TVSIAEIFESLQGESTYAGLPCFFVRLSGCNLRCRYCDTRYAY---------------QAGTETRIDNIVK-----LCRKSKAVITEITGGEPLLQPGFPLAKALRDKGKKVLVETNGSCDISLIPDEVVMDVKCPGSGEKTGFDNIKRLRKYDEVKFVISSRADYLWSKVLFSPVVGKIRPELLGKWIVRDGLPVRLQVQLHKLIGV. 210
108 3.000e-49UniRef50_UPI00040FA1F1 radical SAM protein n=1 Tax=Thermodesulfovibrio thiophilus TaxID=340095 RepID=UPI00040FA1F1  ali  19  1................MKICEIFASIQGESSLVGIPMIFIRLTGCNLRCRYCDTQYSYS---------------EGEELSVDQVIDKVKQFK-----LKYIEITGGEPLLQNEVYELMNNLVKSYNVVLETNGSVSINKVNVKIVMDIKTPGSGMNHRLKNINCLKKTDEVKFVIADREDYEWTKEFINTHTNAEEILELSKWIIQDSLSVRLNLQIHKYI... 201
109 4.000e-49UniRef50_A0A176HC89 7-carboxy-7-deazaguanine synthase n=5 Tax=Oleiphilaceae TaxID=191033 RepID=A0A176HC89_9GAMM  ali  52  2......................FYSLQGEGARAGRAAVFCRFSKCNLWNGREDSRADAVCNFCDTDILGTDGQNGGEFANAQALATKIQSLWDSNQVLPYVIFTGGEPLLQLDPKLIELMHQLGFEIAIESNGTLPLPEGIDWVCLSPKGKSSIVFDRCDELKLVYPQSDALPEAYQDFPADHYFLSPMEDPDKINNTRLALDYCLSHPQWRLTLQMHKLLGI. 222
110 4.000e-49UniRef50_A0A2M7SGT4 7-carboxy-7-deazaguanine synthase n=1 Tax=Deltaproteobacteria bacterium CG_4_10_14_0_8_um_filter_43_12 TaxID=1973958 RepID=A0A2M7  ali  33  110................LKVNEIFYSVQGEGKNSGIPMVFVRLAGCNLRCDFCDTKYA---------------FEAGKEMMVGEILSE-----RGKYPSKWVCITGGEPFIQPLDELARQLKADGSLIQIETNGTIFQPVTCDWLVVSPK------KERRPVESMLERANEIKIVVNLKEALDFTCHSIQPENNHEEATKLCLDFVAEHPQWRLSMQLHKLINI. 298
111 6.000e-49UniRef50_A0A2E2QF29 7-carboxy-7-deazaguanine synthase n=1 Tax=Flavobacteriales bacterium TaxID=2021391 RepID=A0A2E2QF29_9FLAO  ali  28  6...............KLPVTEIFPSIQGEGYFSGKKVTFLRLSGCDVGCPWCDTKYSW-------------EVKENQYMTISQILTKLDLY-----NNKTIVITGGEPMMWNLDLLTLSLKNKGYLINLETSGAYPVSGQFDWICLSFKPVIKDWFFLANELKIIVLNKSDFLWAKKKVNSECKLFVQPEWNNKIKNNFLIDNFISENKKWKLSLQMHKYLNIP 202
112 6.000e-49UniRef50_A0A259SBK4 Multifunctional fusion protein n=1 Tax=Halothiobacillus sp. 13-55-253 TaxID=1970379 RepID=A0A259SBK4_9GAMM  ali  22  314.......AVQEKAPLQLRITEIFRSLQGESESAGWPTVFVRLTGCPLRCVYCDTAYA---------------FTGGERLSLSSILDQVAAY-----HTQDVCVTGGEPLAQPALPLLTSLCDAGHLVSLETSGALSIEGVDVRVVMDLKTPSSGEKNRFENIDLLKTSDEIKFVIGSAEDFKWAVVLISPVFGEVTPLALADWILESGLRLRFQQQLHKLIW.. 526
113 6.000e-49UniRef50_F2NDB6 7-carboxy-7-deazaguanine synthase n=8 Tax=Bacteria TaxID=2 RepID=F2NDB6_DESAR  ali  25  1..............MALRVCETFISIMGEASFAGLPGFFIRLSGCNLRCRYCDTTYAYA---------------EGVERSLASLLGEAGA-----SGYRLVLVTGGEPLLQEELVLLSALVERGFTVLLETNGSRPLEAVDPRVIIDLKCPGSGMHNYLKNLDYLTEKDELKFVVSNRRDFDWAMQVMAASRIWERCTELAAWILATRLPLRLNLQLHKYIWGP 208
114 8.000e-49UniRef50_A0A2H6EC10 7-carboxy-7-deazaguanine synthase n=352 Tax=root TaxID=1 RepID=A0A2H6EC10_9BACT  ali  22  2................LKVNEIYHSIQGESSKAGLPCVFVRLTYCNLRCTYCDTVYA---------------FYDGKEISEEEIIEKVKNY-----GCKLVEVTGGEPLVQDELELMKRLCDEGFDVMLETGGSLPVKDVDKRVIMDLKCPSSGMEKKYGNINYLKNTDELKFVIGNREDYDWTKLKIEEYDNELEPLTLVNWILEDKLDVRFQIQMHKYIWHP 207
115 9.000e-49UniRef50_A0A1F5A0N6 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Aminicenantes TaxID=910038 RepID=A0A1F5A0N6_9BACT  ali  32  1..........MRRPPTLKATEIFASVQGEGLRQGEPTLFVRLAGCNLRCGFCDTKKAW---------------RAGRELPVDAIVEEVARLRL-GYPAAWVCLTGGEPLAQNVRPLVLRLHEADLNVQIETNGTFPPDPRADWHTVSPKPPDPGFFKRAREAKLVVCRDLLDAVRTVRAAFPAATPIFLQPWSRKKALELAGTLRSGLEGVRLSAQLHKVYGI. 208
116 1.000e-48UniRef50_A0A2N1T9Z8 7-carboxy-7-deazaguanine synthase n=1 Tax=Spirochaetae bacterium HGW-Spirochaetae-1 TaxID=2013832 RepID=A0A2N1T9Z8_9SPIR  ali  27  1..............MKLIVKEIFFSLQGETTTTGFPSLFIRLTGCNLRCRYCDSEYAW---------------NGGSEMEIAAIMAKI----HNETGIHHITITGGEPLCQENVYLIKNLCDGGYNVQIETNGSLPLEK-IDRKIVDVKTPSSGEDSLMENLTCLNPHDEIKFVIGDTTDYNFATVNFSPVYGNITYNTMASWILRDRLMVRLNLQLHKI.... 205
117 1.000e-48UniRef50_A0A254QMD1 7-carboxy-7-deazaguanine synthase n=3 Tax=Proteobacteria TaxID=1224 RepID=A0A254QMD1_9PROT  ali  21  2................LKINEIFYSIQGETTYVGAPTVFVRTTACNLRCTYCDTKYSY---------------YEGDMRTMEAIHQEID-----SHKAPHVCVTGGEPLLQKEVHLMKELCDKGYKVSLETSGSKSIVDPRVKVILDVKTPDSGAANLMDNIGFSTASTEFKFVICSEEDFKFVVLYSPSYGQVSE-RWLAEKILQQNSSARLQLQLHKYIWSP 207
118 1.000e-48UniRef50_J9PV61 Putative radical activating enzyme n=1 Tax=Bacillus phage BCD7 TaxID=1136534 RepID=J9PV61_9CAUD  ali  27  2..........AGNAMTLKVNTIFTTLQGEGKYTGYPTTFVRLFGCNMRCTYCDSMYAVVG-------------KQWKTMGVKKIVEEVKKMKN-----KHVCITGGEPLIQENVPLIYELVQAGHTVNIETNGGVELEEREFRYTMDVKGLSSGAENIYENLARLTERDEVKFVIGNIEDYVFAKDVIRKYPTRANIIELAQWIMEDIPKVRLGLQTHKFLNI. 217
119 1.000e-48UniRef50_U7D6T5 7-carboxy-7-deazaguanine synthase n=2 Tax=Chitinivibrio TaxID=1505231 RepID=U7D6T5_9BACT  ali  24  1MPPITSDSPVS----TLTVCELFTSLQGESTHAGRVCSFIRLAGCNLRCHYCDTTYSYG---------------GGQRKSFQELLAWLATEKT-----SLVEITGGEPLCQDAVDFSALLLQQGYEVLVETNGTVSVLPGEVQKIIDYKLPGSGATTPFENFSHISSRDEVKFVISDRADYECAKEIVQNQDIAGEVLFLAEWIVEDRLRVRLGVQLHKVIW.. 214
120 1.000e-48UniRef50_B9XLJ7 7-carboxy-7-deazaguanine synthase n=8 Tax=root TaxID=1 RepID=B9XLJ7_PEDPL  ali  23  4...............TLVVNEIYLSLQGESTFAGLPCIFVRLTACNLRCSYCDTAYA---------------FTEGAKQGMAEMLAEIRTLAAGGHKMPLIELTGGEPLLQPNLPLMKTLCDEGFTVLIETSGAHDISKIDSRVIMDLKCPSSGEVNRRENLRYLKNSDEIKFVIGTEQDYEWAKQQIVEHKLDAICLQLVERIIADALPVRFQLQMHKIIWSP 239
121 2.000e-48UniRef50_A0A1Z4JPM7 7-carboxy-7-deazaguanine synthase n=1 Tax=Leptolyngbya boryana NIES-2135 TaxID=1973484 RepID=A0A1Z4JPM7_LEPBY  ali  27  1........MIRTEAQTLPIVETFHSVQGEGAWTGTSALFIRLGGCDVGCWFCDTKESWVAKRHP-------------RQSIQELVNLAIEV-----NSAIVVITGGEPLMHDLTELTKALKDEGLRLHLETSGAHPFSGTFDWVTLSPKQ-FKPPHE-----SVYAHVDELKVVIAQAADFEWAVRYLQPEWSSQESTSLIFEYVKQQPKWRMGLQTHKLLGV. 202
122 2.000e-48UniRef50_A0A174SRK5 7-carboxy-7-deazaguanine synthase n=148 Tax=root TaxID=1 RepID=A0A174SRK5_BACUN  ali  40  3.................KINEIFYSLQGEGYHTGTPAVFIRFSGCNLKCPFCDTQH-----------------EDGILMSDEDIVTEVSKY-----PAATVILTGGEPSLWIDREFVDCLHQAGKYVCIETNGTRPLPDNIDWVTCSPKQGVKLEITRMNEVKVVYEGQ--DITVYEQLPAGHFFLQPCSCSNTAE----TVDCVMKHPKWRLSLQTHKLIDI. 180
123 3.000e-48UniRef50_A0A2G6PYD9 7-carboxy-7-deazaguanine synthase n=2 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2G6PYD9_9BACT  ali  21  1........MEVQYEPRLKITETFLSLQGEGSHSGLPCYFIRLTGCPLRCVYCDSDYA---------------FQGGEWRSFSAIIDDLK-----QSGCKLVQVTGGEPLAQKAFPFIHQLCEDGFRVLLETSGAISLLHPDCHIVMDIKTPGSHEQDRWNNLDLLKSSDEVKLVLTSMEDWDWAKVLISTIPEPEELKQLVAELIESGINARFQLQLHKIIW.. 213
124 3.000e-48UniRef50_Q9HII0 7-carboxy-7-deazaguanine synthase n=12 Tax=root TaxID=1 RepID=QUEE_THEAC  ali  22  1................MLITEIFHSIQGEGPYAGLPMLFVRTNVCNIRCEWCDTKYS---------------FYGGKEIPLSELLGIVKEAKE-----GWVCFTGGEPLVQRDLAFVKSVVDMGKNVLIETNGTISIRNFVIFIDMDVKPPSAKVTKGMDNLRYLRKQDYLKIVIKDDTDLDFAIDFVDRYGEGSDIRRIADRIVGTGYNVRVLPQIHKII... 202
125 3.000e-48UniRef50_H2CLA2 7-carboxy-7-deazaguanine synthase n=5 Tax=Spirochaetes TaxID=203691 RepID=H2CLA2_9LEPT  ali  23  7...............TLRLTETFLSLQGEGEHAGLLCYFIRTAGCDLRCRWCDTDYSW---------------TGGVKHSLDDIVAGI------PEGVTLVQITGGEPLLQKEVIELIKRLSAEYAVLLETGGHRSIEGLPPHIVLDIKLPGSNEHNFADNLPFLKSSDEIKFVIADRRDYEHRKLLVSPVFGEIAPSDLAQWVIEDRLPVRMQLQQHKLIWDP 212
126 4.000e-48UniRef50_A0A1I4SMB5 7-carboxy-7-deazaguanine synthase n=1 Tax=Thermodesulforhabdus norvegica TaxID=39841 RepID=A0A1I4SMB5_9DELT  ali  26  8..................VSEMFISIQGESSFAGWPCVFIRTAGCNLKCTYCDTLYA---------------RNGGRKVTLRNCLRFVED-----SGLKLVEITGGEPLLQEELPLVKMLIDREYTVLIETNGSLDIIPEKAIRIMDIKCPSSGMKNDYENLKRLHPADEVKFVIGNFEDYLFRVIHFSPVFGLLEPSTLAEWILKDKIPVRLNLQLHKYIWSP 212
127 5.000e-48UniRef50_E5CGP7 7-carboxy-7-deazaguanine synthase n=5 Tax=Bacteroidales TaxID=171549 RepID=E5CGP7_9BACE  ali  37  1..............MK-KINEIFYSIQGEGYRTGTPAVFVRFSGCNLKCPFCDTQHS-----------------SGREMSDEEIIKEVCFYPTRF-----VVLTGGEPGLQVDQEFINKLHQAGKFVQIETNGTVPLPIGIDWITCSPKEGSKVFVVNPHEIKVVYTGQDLSTYEAMTAAV--YYLQPCSCQNTEEVI----NYVKEHPKWKLSLQTQKILNV. 180
128 6.000e-48UniRef50_A0A0W8EGS0 7-carboxy-7-deazaguanine synthase n=4 Tax=Bacteroidetes TaxID=976 RepID=A0A0W8EGS0_9BACT  ali  38  1...................MEQFYTIQGEGANAGRAAYFIRLGGCDVGCHWCDVKESWDADAHP-------------RLTIESLIAEV-----RQHPGRNVVITGGEPLMYDLGPLTQALHAAGCQNWIETSGAHPLSGEWDWICVSFKAPLPEVLLHAHELKVVVFNKSDFAWAEQHAALQCRLFLQPEWSKAAAVTPLIIDYVKQHPQWQVSLQTHKYLDIP 193
129 6.000e-48UniRef50_A0A2M7WEL1 7-carboxy-7-deazaguanine synthase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A2M7WEL1_9PROT  ali  23  2.....PTGVRVVTEIQLSVAEIYRSLQGETSRVGCPTVLVRLAGCPLRCVWCDTPGALLSEQ-------------GKPMSVEAILAAVA-----QAGAGDVLLTGGEPLVQEGAILLGRLVDTGRRALLETSGALPIHAVPVKIIMDLKAPGSGMHNRLANLGLLGPEDEIKIVVADRADFDWAVALCRQHRLTERVRELAQWILDSRMNLRLQLQMHKIVW.. 219
130 6.000e-48UniRef50_P73667 7-carboxy-7-deazaguanine synthase n=116 Tax=Terrabacteria group TaxID=1783272 RepID=QUEE_SYNY3  ali  29  2....SMGPISELLTVSYPIAETFHSLQGEGAWAGGNAFFIRLGGCDVHCPWCDQKETWPTQHHP-------------RQTVTELVQQAVTAKPSF-----VVITGGEPLMHDLQPLCKTLKNQGLRLHLETSGAYPLTGQFDWITLSPK-PYKLPQAAIYPLAN-----ELKVIISQDEDFDWRKISPGTPWETEAMNEKIFAYILTHSQWRLSLQTHKYLGV. 207
131 8.000e-48UniRef50_D0LGT4 7-carboxy-7-deazaguanine synthase n=1 Tax=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) TaxID=502025 RepID=D0LGT4_HALO1  ali  35  1........MPTKHPHSYRVKEIFPTLQGEGTHAGRACVFLRFAGCNLQCSWCDTDFSP---------------EGAERLRADEITERLLALDV--HGARTVIVTGGEPALQWDQELADALRAAGFRVHMESNGTRPPRAPVDWLTVSPKVQFHGPREALSECKLVVDHDTLAALEHHGADL---LLQPCMDADYEQHLARTLTLIGERPRWRLSLQLHKIVGVP 211
132 8.000e-48UniRef50_A0A257NVA0 7-carboxy-7-deazaguanine synthase n=654 Tax=root TaxID=1 RepID=A0A257NVA0_9GAMM  ali  20  1.....MSAIELKEHPQLRITEIFRSLQGESDSVGWPTVFVRLTGCPLRCVYCDTAYA---------------FTGGQRMAINEIMMQVQA-----HQTKDVCVTGGEPLAQPALSLLKELCDAGYAVSLETSGAIDIAGVDPRVVMDLKTPSSGESNLLENLDHLKASDEIKFVVGSAEDFQWAEAQVQHHQLDRRFLMLAEWVLGTGLRLRMQMQLHKMIW.. 215
133 9.000e-48UniRef50_A0A1G3KYL2 7-carboxy-7-deazaguanine synthase n=1 Tax=Spirochaetes bacterium GWB1_36_13 TaxID=1802174 RepID=A0A1G3KYL2_9SPIR  ali  25  1..............MKLKINEIFYSLQGEGSASGYPFIFIRFSNCNLRCLYCDTKFS---------------FNEGEELPVKEVTERISYL----PSVDHILITGGEPLLQKEGLLELLKELMKKKIFIETNGSVDISFLPREIIIDVKTPSSGYPSHIENLKYLTEKDDMKFVISDKEDFDFSVRFIEEHRLINKIEKLAQWILESGLPVRFSIQLHKLLKM. 209
134 9.000e-48UniRef50_A0A1W9M6L0 7-carboxy-7-deazaguanine synthase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A1W9M6L0_9DELT  ali  23  8...............TLRISELFFSIQGESTCAGLPCAFVRLQGCNLRCRYCDAAYS-------------REEEGGHEMSVAAVLDWLA-----QYPGQLVEITGGEPLLQPNVPLMTELLRQGRAVLLETNGSVDISPVPVGVILDVKCPDSGMTDRMEWENLARLGDEIKFVIGSEDDFFWARQLVRDECPAMEPARLAELILTYRLPVRLQLQLHTILW.. 220
135 9.000e-48UniRef50_I4BC20 7-carboxy-7-deazaguanine synthase n=1 Tax=Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) TaxID=869212 RepID=I4  ali  27  1.....MDVTAKREDLKLTVNEIFYSIQGEGSYALHPCVFVRLTGCNLRCTWCDTTYS---------------FYEGEPQTITQILQTV-----TGYAAKNVEITGGEPLLQKNVPLMHALHESGHKVLLETSGSVKVNQVPQFVILDMKAPGSGEHKRYENLQLLKSSDDLKIVIANHEDFQFAEDLIREHKVEELNLAEAGEWLKNSPNLRLGMQLHKYI... 216
136 1.000e-47UniRef50_Q7MR57 7-carboxy-7-deazaguanine synthase n=4 Tax=Campylobacterales TaxID=213849 RepID=Q7MR57_WOLSU  ali  35  2................YPVTEIFYSIQGEGHHSGKAALFVRLHGCNLACDFCDEP--------------SHTQGEYENQSQEAILEQLRAY-----PAHFVVITGGEPTLFDLNPLIKFLQKEGYFVAIETNGYLAHIQAADWITYSPKNWNTLAKEGYDELKFIIHHASDILALFQEKPL-YLQPQSDGSALNAANVARCVELILEHPEWRLSLQTHKILEIP 193
137 1.000e-47UniRef50_A0A1G1NSX9 7-carboxy-7-deazaguanine synthase n=1 Tax=Omnitrophica WOR_2 bacterium RIFCSPLOWO2_02_FULL_50_19 TaxID=1801865 RepID=A0A1G1NSX9_9  ali  22  6............KQPTAKVTDVFLSIQGEGVYAGEPHIFIRFHGCNMRCAFCDTPQ----------------GETPEDSSIRAVVDKITNADKDKKA-KAVTITGGEPLLHPHFLLLPPLRERAYKIHLDTNGTLPVIDLVDIVAMDIKLPSSTKDKHFWEEHIETKEVFIKLVVTSEADMERAVKLVKGVPDNAKLLEWQKKAQSRLKDVRVIPQLHKIIGV. 235
138 1.000e-47UniRef50_A0A1V5GUT1 7-carboxy-7-deazaguanine synthase n=1 Tax=Lentisphaerae bacterium ADurb.BinA184 TaxID=1852901 RepID=A0A1V5GUT1_9BACT  ali  25  2................LHVSEVFRSIQGESTFAGLPCVFIRLAGCNLNCRYCDTRHARQPD---------------RTVPWRGLVDEALAL-----GGGIVEVTGGEPLLQPRTPLLDALAESGRTVLLETNGSLGLPGKRRYVIMDMKCPASGEAAAFPNIGRLTGRDELKFVVSSRDDFDWACQQIERHGLAGRPAELAEWVLASGLPLRMQVQLHKVIW.. 205
139 2.000e-47UniRef50_A0A117LL90 7-carboxy-7-deazaguanine synthase n=2 Tax=Candidatus Marinimicrobia TaxID=62680 RepID=A0A117LL90_9BACT  ali  34  11................YPVNDIFSSIQGEGFWTGLPVTFIRFAGCNLACDFCDTDYSMK-----------------EILTADEILRRLESW-----PAPTVVLTGGEPLIHPLKPLLKRLQSAHYRIHLETNGTFSVPEFFDWIAVSPKTDMP-VLRECNELRVLLKKGEVPRDFNIRAEHYFVSPLNPSLNNPQDNLCYCLEYVLGHPKWRLNVQLHKYLDIP 200
140 2.000e-47UniRef50_A0A2D7DZ16 7-carboxy-7-deazaguanine synthase n=13 Tax=Bacteria TaxID=2 RepID=A0A2D7DZ16_9RICK  ali  47  1..............MMYRIKEIFKSIQGEGFFSGKEALFLRFTGCNLWSGRKKDKSKSICNFCDTDFLGTDGKNGGS-YNLEKLISLIKKIWHYTYTSKFIVLTGGEPLLQVDDLLVNRLKKENFFVAIETNGTINTNLKFDWVTVSPKEDAEWNLKKGDELKVVYPQHKFDLKKIKNLDFKYFFLQPKDEEKNRTNILKTINYCKSHKPWFPSFQIHKPLGI. 210
141 2.000e-47UniRef50_A5D2D9 7-carboxy-7-deazaguanine synthase n=5 Tax=Clostridia TaxID=186801 RepID=A5D2D9_PELTS  ali  26  1..............MRAYVSEIFSSVQGEGLLTGCRQVFIRFYGCNLNCSFCDTKYGGPPACCRIESLPAGGDFRYLPNPLKVGEAASAAASYDLSLHHSVSLTGGEPLLHFLKELIPLVKGTRHGIYLETNGTLPVIDLIDMVSMDFKLPS---VSGMPPF-WEKHWDFLKIAASRKVLVKVVVGQNTAHEEIERVLELQKLALKFLNDVRVIPQTHKVIG.. 243
142 3.000e-47UniRef50_A0A1V4ME53 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A1V4ME53_9DELT  ali  26  18...............SLSVSETFVSLQGEGVWTGWPCFFIRLAGCNLRCTYCDTQYAY---------------NSGEKRDIESLLDEW-----RQAGVGLVQVTGGEPLLQSGTYLLEALLNEGARVLLETNGSLGLKNVPREVIVDRKTPGSAMEEFFENLGWLKQGDQLKFVITARDDYEWARVLFSPAWGGLAPFQLAEWIIADRLSVRFQIQLHKILW.. 222
143 4.000e-47UniRef50_A0A2N1PMF1 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Wallbacteria bacterium HGW-Wallbacteria-1 TaxID=2013854 RepID=A0A2N1PMF1_9BA  ali  25  8...............TLQICEIFTSIQGESTRAGLPCTFIRLSGCNLKCSYCDTLHSHLP---------------GTTRSIDWIMNQVS-----QAEIPLVEITGGEPLLQENVLLVDSLLSMGFTVLIETNGSVDI----DRVIMDVKCPGSHESTLETNFRILQPSDEVKFVLTSAEDYDWALEHINEFDLINRCHTLAEWILRDRINVRLQVQLHKIL... 211
144 5.000e-47UniRef50_C9RBW4 7-carboxy-7-deazaguanine synthase n=1 Tax=Ammonifex degensii (strain DSM 10501 / KC4) TaxID=429009 RepID=C9RBW4_AMMDK  ali  23  11................APLREIFSSVQGEGPYVGVRHLFVRFAGCNLTCRYCDTPRDIPATCRVEVVAGRQHFFHPNPLTPEEVVLLVSNLL-RQLRHGAVALTGGEPLLYPAFELLPALRQIGCRVYLETNGTLPVADLVDVVAMDLKLPSSTYWSEHEEFKLKGKEVILKAVVSRQATREEVVLVLQPVTTKMRLLEMQEWALGKTSDVRLIPQVHKF.... 247
145 5.000e-47UniRef50_A0A1F9Y6T1 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1F9Y6T1_9BACT  ali  24  1..............MTGRISEIFSSVQGEGIYAGTPMIFVRFAGCNLKCDYCDTPESQSLEN-------------GKILSAEEIIKHVENEFENSKNTSIVSFTGGEPLLHSELIIVPYFKGKEIKIYIDTNGILKITDFIDFVAMDIKLPSSCYAEYWKELKISKNKTFIKIVLTAKTAYDISIPLVLQPVTAVRNIEVIRAFKKKLTNVSIIPQIHKRMGI. 229
146 5.000e-47UniRef50_A0A133SBS3 7-carboxy-7-deazaguanine synthase n=6 Tax=Firmicutes TaxID=1239 RepID=A0A133SBS3_9FIRM  ali  27  4...............SLCVNEIFDSIDGEGKTAGQLASFIRLCGCNLRCSYCDTTYA---------------FTEGKDMDVDDIVKQVSY--------PHVTLTGGEPLCQDVHALLAALK--GHSVNIETNGSVDIEPYFKYDHVWFTVDYKSLSSDMSNFEKLRPQDVLKFVVGDEADLKYRRYQPKCAVYVGAIFAQIVDFMKEHEDWHLQVQLHKIIWDP 205
147 7.000e-47UniRef50_A0A1T4K6B7 7-carboxy-7-deazaguanine synthase n=1 Tax=Selenihalanaerobacter shriftii TaxID=142842 RepID=A0A1T4K6B7_9FIRM  ali  21  1................MLVNNIFSSIQGESTYSGFPTTFIRLTGCNLRCSYCDTEYAY---------------KKGEELSIDEVITKVIDL-----NNDYVCLTGGEPLFQSNIQLINKLFKEGYEVSIETNGAVDLEGFNIKVVMDFKLPSSGEFDNYENLQRISKKDDLKFVIGDKEDFLFAKNVIIDKELQKKVLELVKWLLEELNKCRLQLQLHKIIWD. 211
148 7.000e-47UniRef50_X0SKU2 Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X0SKU2_9ZZZZ  ali  22  2................FKVCETFISVSGESGWQGLVATFIRFSGCDVDCSWCDTAYA--------------RQEDGTEVSLPELMSICRANQVHR-----VVLTGGEPLLQKELPLCKALLDEGFDVQVETSGTRMVDKLDKRVVLDIKPPSARAQKGWGNLDLLGKRDEIKFVLADREDYDWALSIIRKCKLENRCKRLAEWMIEDGLSVRLQLQLHKILW.. 206
149 7.000e-47UniRef50_UPI0004793CB6 radical SAM protein n=1 Tax=Holophaga foetida TaxID=35839 RepID=UPI0004793CB6  ali  24  2.............GVTFLINEIFTSIQGEGTRAGRLCLFIRTAGCSLRCRYCDTTYA---------------FSEGRPMSGGEILREVHRLPGKGPNAPFVEITGGEPLDQAGTPLMQALLEGGYEVALETAGSHDVVPRDVVKIADRKTPGSGMSQRWLESNLDCLQDELKFVLCGEDDYAWARTLFSPVWGKLDPRWLAERIVADALPVRFQLQLHKLVWPP 219
150 7.000e-47UniRef50_G4D5E0 7-carboxy-7-deazaguanine synthase n=1 Tax=Peptoniphilus indolicus ATCC 29427 TaxID=997350 RepID=G4D5E0_9FIRM  ali  23  4......................FYSIDGEGPNSGKLSVFIRLNYCNLRCSYCDTEYA--------------FKRVYNFMTVNEIIDEVESYK-----IKSVTITGGEPLAQDLEELISGLLKLGYEIDIETNGSKDVSKYLVNIILDIKTPTSKMENLYENLKLLRGNDVVKFVVADEFDMNFIVEVMKLYPTDAQIIDKLVEYMKNYRNARLQLQIHKYIWD. 200
151 1.000e-46UniRef50_D0JBB0 7-carboxy-7-deazaguanine synthase n=11 Tax=Bacteroidetes TaxID=976 RepID=D0JBB0_BLASB  ali  30  2..............ISFPIKESFYSIQGEGFYYGMAAFFIRFEGCNIKCDWCDTKESWKIKKKDF-------------IPIHEIINHISNY-----TVKNIVITGGEPMMWNLYHLTKILKKKGYRIHVETSGTYPIEKYMDWITVSIKLPLEENYKKTNELKIIISNEDFLFAEEQAIHVKCFLFLQPEWTNFVTIFPKIISYIKENPKWRISLQIHKMLNIP 201
152 1.000e-46UniRef50_F8NB11 7-carboxy-7-deazaguanine synthase n=47 Tax=Bacteria TaxID=2 RepID=F8NB11_9BACT  ali  38  4...............TYRVNDIFYSLQGEGRNTGRAAVFVRFSGCNLRCPFCDTDFT-----------------NYEELTASKILSRMKELSYCTEGMPMVVLTGGEPTLQADEALIDYIHAAGFSVAMESNGTHEPPKNLDWLTVSPKGNVTIKHCNELKVLFDGSTDPQRYEINAGLYY----LQPLDSGEKKRIMRQCVDYIMRHPQWRLSLQTHKLIGV. 195
153 1.000e-46UniRef50_E4TSD7 7-carboxy-7-deazaguanine synthase n=18 Tax=root TaxID=1 RepID=E4TSD7_MARTH  ali  27  7...........DPNIELPLMESFYTIQGEGFHSGKAAYFIRLGGCDVGCVWCDVKDSWDAD----------------KWPLKKIDDIVDD--AYQYESRLAVITGGEPFMYDMHGLTKRLLQKGFHVNVETSGAHPFTGMVDWVCLSPK------KFKAPLEHWYDRADELKIIIFNKSDFKWALMLQPEWSKREEMMPLIVEYVKENPNWGISLQTHKYLQIP 207
154 1.000e-46UniRef50_A0A2A5XJS4 7-carboxy-7-deazaguanine synthase n=3 Tax=Bacteria TaxID=2 RepID=A0A2A5XJS4_9BACT  ali  29  1MNYSIETIEKVQQGCMLPVMEHFYTIQGEGFHSGVACYFIRLSGCDVGCQWCDVKESW-------------EQYSHPLYKVEDMVEWVS-----LSGAVRVVVTGGEPLIHKLDILCDLFRNKGIKCHIETSGAHPYSGTWDWFTLSPKLPLKENYSKAQELKVVISRANFRFAEESKVNDDCKLYLQPEWSKEADILKDIIAYVKINPSWHISLQTHKYMDIP 212
155 1.000e-46UniRef50_A0A1F5B4X1 7-carboxy-7-deazaguanine synthase n=5 Tax=root TaxID=1 RepID=A0A1F5B4X1_9BACT  ali  27  1..........MRRPPTLKTTEIFASVQGEGLRQGEPTIFVRLAGCNRRCGFCDTKKAW---------------RGGREMPVEKIVDEVGRLR-RGVPAAWVCLTGGEPLAQDVRSLVLRLHEEGLKVQIETNGTFPPDPRADWHTVSPKPPDFDVHPGFVRRAREVKLVTLDDVRTVRAVFPRATPLILQPWSRKKALKILEDYRSGLGGIRLSVQLHRVYGL. 208
156 2.000e-46UniRef50_P64555 7-carboxy-7-deazaguanine synthase n=2441 Tax=root TaxID=1 RepID=QUEE_ECO57  ali  31  1..............MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESASSEDLLAVIGRQ---GYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNWVTVSPKLALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIAR-NWRLSMQTHKYLNI. 222
157 2.000e-46UniRef50_A0A1F3XVW2 7-carboxy-7-deazaguanine synthase n=1 Tax=Bdellovibrionales bacterium RIFOXYD1_FULL_53_11 TaxID=1797403 RepID=A0A1F3XVW2_9PROT :_  ali  23  1................MRVHGIIHSIQGESTLIGVRTAIVRLSGCNLRCRYCDT--------------VTASRGRGREMSIPEILRAVKIL-----GVKFALLTGGEPLLQKDAPLVRALRSRGFFVSVETNGETPIPPVIAHVVMDIKTPGSRIKRAADNLGILKKTDELKFVITSEKDYRWRTTLFSPAGRGPRARRLAGWIIRDKLDARLQLQLHKAIGI. 214
158 2.000e-46UniRef50_Q97D55 7-carboxy-7-deazaguanine synthase n=151 Tax=Terrabacteria group TaxID=1783272 RepID=QUEE_CLOAB  ali  21  1..............MNYKVVEKFVSINGEGLKSGQLSVFIRFAGCNLNCNYCDTKWA------------NEKDVKYTLMTEKEILSYIKE-----TGVKNVTLTGGEPLLQDGELLNLLSLDSTLRVEIETNGSVSLENFLNFFTMDYKLPDSSMENFMSNFKFLNKKDVIKFVVSSLKDLKKAMDIITEFNLSKKSPETIVDFMKDNKDVTLQIQIHKIIWNP 216
159 2.000e-46UniRef50_E4Q980 7-carboxy-7-deazaguanine synthase n=18 Tax=Terrabacteria group TaxID=1783272 RepID=E4Q980_CALH1  ali  23  7.........KSENPIKFNVVEKFVSIEGEGIRSGYPAVFVRFAGCNLRCSWCDTKYANENP-------------EYEEIDIDNLMNFI-----TSTGIKRVTLTGGEPLIQPIYLLIDRLISEGFEVNIETNGSVSIKHVPRIITMDYKCPSSGMEDRMDNIHFLGQKDVLKFVVSTYEDFKPRCIFFSPVFGKIEPREIVKFVLENGLDARVQLQLHKIIW.. 218
160 2.000e-46UniRef50_A0A1G5RZ86 7-carboxy-7-deazaguanine synthase n=5 Tax=Clostridiales TaxID=186802 RepID=A0A1G5RZ86_9FIRM  ali  23  3...............QYKVVERFVSINGEGPSAGQLAVFIRFKGCNLACSYCDTAWANTENAAFTS------------MSEDDIYRYIKE-----TAIKNVTLTGGEPLLQPIDLLKLLATDEALHVEIETNGSIDITPYTPVFTMDYKLPGSLMESSMSNFERLTQKDTLKFVIGSLEDFNVARDIIHRHALVGKCLEEIVELMKDHNGVNLQLQMHKIIWDP 217
161 3.000e-46UniRef50_A0A174PZK4 7-carboxy-7-deazaguanine synthase n=28 Tax=Bacteria TaxID=2 RepID=A0A174PZK4_9BACE  ali  20  18................FHVTEIFDSIDGEGKRTGLMAIFVRLAGCNLRCSYCDTAYSLSLTDTA------------EALTEEELLSRIHAF-----PWKKITLTGGEPMLHPIRRLCEVLGKEGYEVNIETNGAVVLFQERPFYTMDFKCGGSGMKERMENFRLLGKEDVLKFVVSSKADMDFYVSPVWGRIAPANLVEYVRR--ERLNDVRVQVQLHKIIWDP 228
162 3.000e-46UniRef50_A0A2E9KWV0 7-carboxy-7-deazaguanine synthase n=6 Tax=Bacteria TaxID=2 RepID=A0A2E9KWV0_9SPIR  ali  22  1..............MKLRVNEIFQSIQGEGIQIGAPTIFLRLFGCDLRCAWCDSMHAVEGS-------------DYQNITLDDIIQEAE-----SHDCKNICITGGEPLLQQDVPLIDILIQKKYNILLETSGHIRPNNPNVLISMDCKCPGSTMEKKTDFLESLQEKDQIKFVINDKSDYEFRATIVFQPVYGTDISFLVDLALKDNLNIKVLPQLHKLIW.. 208
163 3.000e-46UniRef50_C9LE55 7-carboxy-7-deazaguanine synthase n=51 Tax=root TaxID=1 RepID=C9LE55_9BACT  ali  36  3...............RFKINEIFYSLQGEGFYSGIASIFIRFSGCNLSCSFCDTQH-----------------ETGELMTQEQILDQVTRF-----PAKHVVLTGGEPSLFVTKELIDGLHAAGKYVCIETNGLHALPEGIDWVTLSPKTA-QTILKTCNELKVVFTDDTFNPHDEIKAAHYFIQPCDMGNSKNNRILASCISYVKENPRWRLSLQTHKMIGI. 188
164 3.000e-46UniRef50_A0A2A4UF05 7-carboxy-7-deazaguanine synthase n=3 Tax=Proteobacteria TaxID=1224 RepID=A0A2A4UF05_9PROT  ali  20  2................INIHEIYQSIQGESTLAGMPCTFVRLAGCPLRCTYCDTLQAI-------------PFDSGKSMDMDDVVAQVKAWSN-----PLVLVTGGEPLAQKCIDLLQKLLDTGVIVQLETSGALDAVPIAVRKVMDIKTPGSGEEKRWQNLQYLHSHDEIKFVLKDQADYAWATILLSPCWGELNPEDLCAWILRDKLAVRMQIQMHKVIW.. 207
165 3.000e-46UniRef50_A0A2N2AQ80 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Firmicutes sensu stricto (miscellaneous) TaxID=84086 RepID=A0A2N2AQ80_9FIR  ali  27  1..............MT-NLVEIFSSIQGEGIYTGARQVFVRFSGCNLKCAYCDTPYEPNPRFRVEFPAGTREFNYSNPAGPDETAEIIKKF--NLKKHHSISLTGGEPLLHTKFILQLLLKAEGTMFYLETNGTLPLIPVIDIVSMDIKLPSTSELSGLWDTHSEFKEVFVKTVVSSGVNPKIPLIIQPKSPSIRRVIKLQELALDYLTDVRVIPQTHKYLG.. 243
166 4.000e-46UniRef50_A0A2D5ZZK4 7-carboxy-7-deazaguanine synthase n=2 Tax=Bdellovibrionaceae bacterium TaxID=2026715 RepID=A0A2D5ZZK4_9PROT  ali  24  10...............QIKINEIFFSIQGESTRFGLPTVFVRTSGCHLRCTYCDTTYAY---------------HKGEWQTVDNIVDKIREY-----PTRYICVTGGEPLLQKALPLMVQLSDEGYXVSLETSGSCEXVDPRVKKIIDVKTPDSGAFEAFSEKNLQLDDVNFKFVICSEKDFNWSVQFCVDNNLFEKFKWLAKKILSVSHPIRLQLQMHKYIWSP 216
167 4.000e-46UniRef50_A0A0J7HTX3 7-carboxy-7-deazaguanine synthase n=1 Tax=Chitinispirillum alkaliphilum TaxID=1008392 RepID=A0A0J7HTX3_9BACT  ali  22  1................MEVIEIFKSIQGESSYSGRLCSFVRLKGCNLNCVWCDTEYAVN--------------ENGTVLDVGEIVSLVK-----QHHTKLVEITGGEPLLQDSTPLCSEFLDRGYTVLVETNGSLDIGKLPVLRIIDIKCPDSGESFRMDNLDLLTKQDECKFVVASVKDLNWASSFIKKHDLTSRCTEVADFIVENSMDVRLGVQLHKLIW.. 205
168 4.000e-46UniRef50_E8UYW0 7-carboxy-7-deazaguanine synthase n=26 Tax=Acidobacteria TaxID=57723 RepID=E8UYW0_TERSS  ali  23  1................MHLIELYKSVQGESSFTGMPCIFVRSAGCNLRCAWCDSEYT---------------FSGGTPFTEDEIVAQIEALA----PCRLIEFTGGEPMLHAKELLPLMRRLRGYTLMMETSGERPLQDVPVHKIVDVKCPGAGSSFRMSNLDILTQRDEVKFVLRDRVDYEFARDFIREHSLNEDARHLVDWMLADGLDARLSLQVHKFIWEP 224
169 4.000e-46UniRef50_Q1NU31 7-carboxy-7-deazaguanine synthase n=3 Tax=Deltaproteobacteria TaxID=28221 RepID=Q1NU31_9DELT  ali  26  6...............SLLLSEIFYSIQGESTLAGYPCLFIRLAGCNLRCSYCDARYTYEEP--------------GQSYSLEGVLKAMAEVGPGGRPVELVEITGGEPLLQEGVPLLDVLLARGHQVLLETNGTRSLLPAAVRCIMDIKCPASGMAAHFENLHRLTGDDEIKFVIGNRADYDWATLTFSPVTDRLAAADLAAWLLADALPARLQLQLHTLLW.. 217
170 5.000e-46UniRef50_UPI000B7EA628 7-carboxy-7-deazaguanine synthase QueE n=1 Tax=Dehalobacterium formicoaceticum TaxID=51515 RepID=UPI000B7EA628  ali  24  1..............MKGTLHEIFSSIQGEGLYVGVRQIFLRFTGCNLHCSYCDTNDSREKFPVEMDPGTSRFEYYRNPVAPEELLKIVLQLKPEIH--HSLSLTGGEPLLQADFLAEFLPLFRGRPVFLETNGTLPLLPYLDIISMDIKLPSVTNYACWHDQ-----EEFINIALEKELYVKVVLTENTTQEELEQIMKLMAKFGTALKNVRVIPQTHKILNL. 244
171 6.000e-46UniRef50_A0A1G0G7F7 7-carboxy-7-deazaguanine synthase n=4 Tax=root TaxID=1 RepID=A0A1G0G7F7_9GAMM  ali  22  1................MKITEIFFSLQGETKTVGLPTVFVRLTGCPLRCQYCDTEYA---------------FSGGKNYSIDDVIKNIEKYST-----KYVTVTGGEPLAQKELLLLKTLCDLQYYVSLETSGALDISEVDSRVIVDIKTSLESSKNNFDNIKYLLSHDQIKFVICDRNDYEWSKKIMLQFELNKKCETLADWILADQLPVRFQVQLHKVVW.. 204
172 6.000e-46UniRef50_A0A1G0WFG0 7-carboxy-7-deazaguanine synthase n=1 Tax=Lentisphaerae bacterium GWF2_38_69 TaxID=1798570 RepID=A0A1G0WFG0_9BACT  ali  23  3...............TLQICETFTSIQGETTHIGKPCFFIRLSKCNLNCRWCDTKYA-------------FSDLDSKEIKIDELIEMAI-----LSGVKLVNVTGGEPLLQENIELLNKLIKKGFTVLLETNGSIPIKKVPDIIILDFKCPSSGYSEKMENYQMLKKMDEVKFVIENEKDYRFALILFSPVLSKLAPRFLANWMIKDKTPAILQVQLHKFIW.. 210
173 6.000e-46UniRef50_A0A2H0LW68 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_42_13 TaxID=1974746 Rep  ali  22  3...........RPSITGKVSEVFSSIQGEGLYTGARQIFIRLYGCNLKCAFCDT-----------------NMPGYEKYTPEELCDMILKFERNYHS---VSITGGEPLMQKDFEALKLLKKEGIKTYLETNGILEVIDYLDIIAMDFKLPTSGKHDEYWDEHR----EFLKIASKKEVFVKCIVCLSTHHEDMEEVITLIKDSGKDIPDVRIIPQVHKYL... 225
174 8.000e-46UniRef50_A0A1Z5HXH6 7-carboxy-7-deazaguanine synthase n=1 Tax=Calderihabitans maritimus TaxID=1246530 RepID=A0A1Z5HXH6_9THEO  ali  24  1..............MRSPISEVFSSIQGEGLYVGRRQIFIRFAGCNLSCAYCDTIESRSGKVKYCNIEVKPGRQLPNPLSVEDLLDNIVDLLEF--PHHSVSLTGGEPLLYHHFETGKRLKEKEQLIYLETNGTLPVLPYVDIVSMDVKLPTHTGKSYWAEHKEFRKEVFVKIVVSAGVDYNIVLQPVTPVREEMDLMYLQDMALEKLAQVSVIPQTHRLVGV. 246
175 9.000e-46UniRef50_A0A1W9S011 7-carboxy-7-deazaguanine synthase n=1 Tax=candidate division Zixibacteria bacterium 4484_93 TaxID=1970780 RepID=A0A1W9S011_9BACT  ali  25  1................MLISEIYKSINGEGRFAGFPTSIVRVAGCNLNCSWCDTTYA---------------LTGGERLPLDEIMSKIREF-----NTSRVLITGGEPLLQEETELARRLLEIGYHTLVETNGSLPIDALPVFRCVDIKTPSSGEKNLLENIDYLLHTDDVKFVIADRDDFNWSIVLFSPVWGRLPPDTLARWILDSGMDIRLNLQLHKLIW.. 204
176 9.000e-46UniRef50_A0A1H3X926 7-carboxy-7-deazaguanine synthase n=2 Tax=Arachidicoccus rhizosphaerae TaxID=551991 RepID=A0A1H3X926_9BACT  ali  34  20...............SLPVMEAFYTLQGEGNYQGRAAYFIRLGGCDVGCVWCDVKESWDAELHPVKTVEQIVQDAIQEILSDEIASGAESMEALGDAAGTVVVTGGEPLMYELGPLTKALHAAGFRVHIETSGAYPLSGEIDWVCVSFKAPLPEVISRAQELKVVVFNKSDFLWAEQHAAPDCKLYLQPEWSKEKQMLPLMIDYVKTHPTWSLCVQVHKYINVP 247
177 9.000e-46UniRef50_A6H1N2 7-carboxy-7-deazaguanine synthase n=453 Tax=root TaxID=1 RepID=QUEE_FLAPJ  ali  29  1MLTKEIQIAVEKGEM-LPLMEEFYTIQGEGYHTGTAAYFIRIGGCDVGCHWCDVKESWNAALHPPTKT-------------DVIVENATKYAK------TIVVTGGEPLTWDMTVLTQRLKAENLQVHIETSGAYPVTGAWDWFCLSPKLPVAEAYEIAHELKVIIYNKHDFIFAEAKVNKNAILFLQSEWSKKEEMTPFIVDYVMNNPKWRVSLQTHKYLNIP 210
178 1.000e-45UniRef50_F9VNF3 7-carboxy-7-deazaguanine synthase n=26 Tax=Sulfolobaceae TaxID=118883 RepID=F9VNF3_SULTO  ali  24  3...............KYWISEIFTSIQGEGEVIGTPSNFIRLAGCHLRCIWCDTKYAWH-------------KYDGEEMSIEQILDKIDKRIKFT------TITGGEPLLQDILPLVEALKSLNHKVLVETSGTIKPSKLVDIFSVSPKLSNSGYKFKYNFKDLEDIQEIIRFIRENNIEPSKVILQPDGENYTEGLRELIDIILKLGIPFRVLPQFHRIVGI. 211
179 1.000e-45UniRef50_A0A1F9HTY1 7-carboxy-7-deazaguanine synthase n=1 Tax=Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_46_8 TaxID=1797879 RepID=A0A1F9HTY1_9  ali  26  1..............MQFKLAEIFYSIQGEGIHVGRPSVFIRAALCNLRCVWCDTSYTWDWKKQGKEKAAIK-------MSVEDVIQSIQ-----QWHCKNLVFTGGEPMLQQTIELMKKLKPKGYRFEVETNGTIPIELKFDALIDQYNCSPKLSSSK-NGKKLRETEAFFMYAKNPKAWFKFVLTAPEDLN---EINRLVKKYDLDLSRILLMP......... 187
180 1.000e-45UniRef50_A0A1M5D862 7-carboxy-7-deazaguanine synthase n=4 Tax=Bacteroidales TaxID=171549 RepID=A0A1M5D862_9BACT  ali  28  1..............MKLTVNEIFYSLQGEGGRVGEPSIFIRLTKCNLACSFCDTDFA-----------------DGDDMSLDEILGIISRY-----PCKWIIWTGGEPTIQLKNEYLAFFKEHGYKQAIETNGTKRVPTLIDYITCSPKQNYSRIKDLIPKVDEIRIDVLPDIAIFPKADKYFISPIFDGDVPNTENINYCVEQVKLDPRWTLSLQVHKLIHI. 192
181 1.000e-45UniRef50_J7T632 7-carboxy-7-deazaguanine synthase n=18 Tax=Bacteria TaxID=2 RepID=J7T632_CLOS1  ali  21  5.............KMDFKVVERFVSINGEGRRSGQLAIFIRFAGCNLNCSYCDTLWA------------NEKDVSYQLISSKDIYDYIKSQK-----IKNVTLTGGEPLMQKIVELLKLSKDKELYVEIETNGSVLLDEFLDIFTMDYKLPSSNMENKMDNFRYLTNKDTVKFVSGSIEDLEKAKEIIKKYNLVKINLDTIVEFMKNNKGVNLQLQLHKIIWDP 221
182 2.000e-45UniRef50_A0A1V2YHT0 7-carboxy-7-deazaguanine synthase n=1 Tax=Epulopiscium sp. Nuni2H_MBin001 TaxID=1884656 RepID=A0A1V2YHT0_9FIRM  ali  23  1................MKVVEKFVSIDGEGPMAGELATFVRFEGCNLRCSWCDTSYSWDGES--------------ESLTASQIYDYII-----STGINHITLTGGEPLLHEDIEVLLAKLSDNYNVNIETNGSVLIAPFNIRYVIDYKLPDSGMTNKMDNLKAVTANDTYKFVIASSQDLEKAYELICEYDLEQINPQVIVDYMKQIQNIRLQLQLHKFIW.. 211
183 2.000e-45UniRef50_A0A1F9UJZ7 7-carboxy-7-deazaguanine synthase n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_59_12 TaxID=1797946 RepID=A0A1F9UJZ7_9BACT  ali  28  5...............KASVLEIFKSRQGEGLFAGEPHLFVRFGGCNLVCDYCDTPDSI-------------PVQSGTRWDLDGVLARLGHLRGDGGPSV-VSLTGGEPLLHADFLLVPRLRALGYRVHLETNGSLPIIKGCDWIAMDFKPDSATGRDLWEAHRWFLEKVFVKMVLTGKAEAEFRVLQPATPWGSARSIPLAEWAARRLRDVRIIPQIHRLWEI. 231
184 2.000e-45UniRef50_A0A1F3B7A7 7-carboxy-7-deazaguanine synthase n=1 Tax=Armatimonadetes bacterium RBG_16_58_9 TaxID=1797287 RepID=A0A1F3B7A7_9BACT  ali  23  2..........QAHGPRGWIHEIFTSVQGEGIYCGCCHTFVRFARCNLECDYCDTPTSREPHPCRVEPEPGTGRFEENPLTARQVTEACASLPARVAA-----LTGGEPLLQHEFELMREMKERGCSTYLETNGTLWVVGMTDVIAMDIKLPSSTGGAAMWDERFLRIEVFVKAVVDARVAVDRRIPLVIQPVSGAKLMALQRRALERLEDVRVIPQVHKVLGI. 244
185 2.000e-45UniRef50_E4T1V8 7-carboxy-7-deazaguanine synthase n=14 Tax=Bacteroidetes TaxID=976 RepID=E4T1V8_PALPW  ali  29  1.......MRSKADEILLNVVEIFHSIQGEGANAGRSAVFVRLSNCNKNCWYCDTDWS-----------------KGETMSVSQILAEVNKFVGKKYPNNLIIWTGGEPTLQLTDEILSHFSE--YYNCIETNGTNPVPSLIKYISCSPKVKPEVLRKNFKHVNEFRYDVLPDIAELPAADNYIVSPIFLGFEQVDENVKYAIDFVKKNPRWRLSLQLHKLLNIP 209
186 2.000e-45UniRef50_A0A174M864 7-carboxy-7-deazaguanine synthase n=31 Tax=Bacteria TaxID=2 RepID=A0A174M864_BACUN  ali  36  1..............MK-KVNEIFYSIQGEGYHTGTPAVFVRFSGCNLKCPFCDTQH-----------------EDGILMSDEEILSEVGKY-----PAVMVILTGGEPSLWIDREFVDRLHRIGKYVCIETNGTRSLPNNIDWVTCSPKEGSNAIVVNPHEIKVVYTGQDLSTYEEMTAAV--YYLQPCSCQNTEEVI----DYIKKHPKWKLSLQTQKILNV. 180
187 3.000e-45UniRef50_A0A1M6SC08 7-carboxy-7-deazaguanine synthase n=7 Tax=Fibrobacter TaxID=832 RepID=A0A1M6SC08_9BACT  ali  32  4...............TYRINTIFFSIQGEGKRVGTPQVFVRFSGCNMKCPFCDTNH-----------------EPFTEMTAEQI---IAKAKEVGGNCRSVSFCGGEPTLQLDAELIKAF--EGWYKSIETNGTKPVPAGIDYIVCSPKTS----------RIEPDNIDELRFVIKAGDPLPCLSPCFDGDNLVRENLDHCIELVKQNPGWILSLQWHKFIGI. 188
188 3.000e-45UniRef50_A0A0F2N4M2 7-carboxy-7-deazaguanine synthase n=1 Tax=Peptococcaceae bacterium BRH_c4a TaxID=1629716 RepID=A0A0F2N4M2_9FIRM  ali  24  1..............MKCHIREIFSSVQGEGPYLGIRQIFVRFEGCNLSCHYCDTKTHGKGAGCSVEVDPGNKKFIENPMSSSDLLGIITG-SFDLSLHQWVSITGGEPLLQALMELLPGLRDLGLKIYLETNGTLPIVDMVDVVAMDIKLPGTSGCQPMWNRHSQRTGVFVKIVMDDGADVEYITLVIQPVTLNGKCLYLQSMALKRLRDVRIIPQAHKMM... 242
189 3.000e-45UniRef50_E6Q1H4 Uncharacterized protein n=4 Tax=root TaxID=1 RepID=E6Q1H4_9ZZZZ  ali  37  9...............TLHVTEIFYTLQGEGTWAGTPAVFIRLAGCNLACAFCDTDYALR--------------------SLESIADIVARVDQLGGACPMVVLTGGEPLAQSATALVDALRADGRRVHIESNGTIFELPADVWLCVSPK-------ERVDA-RMARRADEVKLIVDRRVPEEHLTIFLQPEGNKPSNVALAVDYARAHPRFRLSLQTHKFIGIP 199
190 4.000e-45UniRef50_UPI00040C8008 7-carboxy-7-deazaguanine synthase QueE n=2 Tax=Sporomusaceae TaxID=1843490 RepID=UPI00040C8008  ali  32  1..............MNYPVLELFSSIQGEGYYQGTLASFVRLGGCNLRCSWCDTAHSQ-------------TAAEAKDMDIADILLQLPRDVRR------VIITGGEPTLHDLGPLAAALHARGHEVALETNGTVPAEWGIDWIAVSPK-PDAAYGVRCDELKYVVDERLQAEHIQDSLVLEGRVYLQVEGGRPASALR-ALELVRANPGWRVGVQLHRVLQVP 195
191 4.000e-45UniRef50_S7VJJ6 7-carboxy-7-deazaguanine synthase n=39 Tax=Bacteria TaxID=2 RepID=S7VJJ6_9FLAO  ali  30  16................LPLMEEFYTIQGEGFHKGTAAYFIRIGGCDVGCHWCDVKESWLAELH----------------PPTEITKIVENAEKYSK---TIVVTGGEPLMWDMDPLTKQLKERGLQTHIETSGAYKLTGDWDWICLSPKLPTEEVLEKAHELKIIFNKDDFKFAEEAKVNKDCILYLQPEWSKSDKMVPQIVDYVMANPKWKVSLQTHKYLNIP 210
192 4.000e-45UniRef50_A0A177Q227 7-carboxy-7-deazaguanine synthase n=3 Tax=Bacteria TaxID=2 RepID=A0A177Q227_9BACT  ali  26  15....................EIFASVQGEGLSAGLPSTFVRTAICNLRCSWCDTAYTWDWSRYDRAEQVLA-------IDPDEVLRRVRALPPRN-----VVITGGEPLIQQLAALVSALKDDGYRVEFETNGTIAPGELTPL-ADQWNVSAKLAHSGNEGLQRRRPGALAAFAALSHANFKFV---VRAMGDLEELEALAVEYQIQADRIVLMP......... 195
193 4.000e-45UniRef50_G2YZU9 7-carboxy-7-deazaguanine synthase n=872 Tax=root TaxID=1 RepID=G2YZU9_FLABF  ali  31  1MLSKESQTAIQKGEL-LPLMEAFYTIQGEGAHTGTAAYFIRIGGCDVGCHWCDVKESWNADLH----------------PPTAITTIVEEAKLYSN---TIVVTGGEPLMWNMDGLTQKLKRVGMTIHIETSGAYPLTGIWDWICLSPKLPLPEVYEKANE---------LKVIVHNKHDFEFALFLQAEWSKKDMITPFIVDYVMNNPKWRISLQTHKYLNIP 210
194 4.000e-45UniRef50_A0A1J4Z5S7 7-carboxy-7-deazaguanine synthase n=3 Tax=unclassified Candidatus Omnitrophica TaxID=1047005 RepID=A0A1J4Z5S7_9BACT  ali  23  1..............MLAKIHEIFTSIQGEGILSGKRQVFVRFFGCGFGCSFCDTPQ---------------EAHEMKEYTAEELLSAV-FIKALPKSIHSVSITGGEPLLQADFIFLPRLKQTGYKVYLETNGALPIIDYVDIIAMDIKLPTSTLAKGLWQEHSQTKQVFVKIVVTDKTDFNRAVLVIQPVTDHALMLESFKKIAKEHLRVKVIPQMHKIYGI. 226
195 5.000e-45UniRef50_A0A1M6YCQ1 7-carboxy-7-deazaguanine synthase n=7 Tax=Fibrobacter TaxID=832 RepID=A0A1M6YCQ1_9BACT  ali  19  1................MKVSEIFLSIEGEGIRTGAPAVFVRLFGCNLRCSYCDSMYAVEGS-------------DFQELSPVEVFEKVKSF-----NTQFVTLTGGEPLIHKDVEVLLKMLDYGLEVNIETNGTQPKPSGYRFCTMDWKSISSGMQPKMENMMTLSGRDVLKFVVGTEEDLKLPTFYVSPIFGTMKYEDMVDWILMKRNNVRFQVQLHKVIWDP 218
196 6.000e-45UniRef50_A0A1H7ZWL4 7-carboxy-7-deazaguanine synthase n=2 Tax=Candidatus Frackibacter TaxID=2017975 RepID=A0A1H7ZWL4_9FIRM  ali  23  1................MLVNNIFSSIQGESIYSGFPTTFIRFTGCNLKCDYCDTTYAY---------------EEGEELNTEAIMEQVEKL-----NNNYVCLTGGEPLLQEDVQLINELTNYGYQISIETNGTVALDQFNVKVVMDLKLPSSGEYRSENNIRTLNNKDDLKFVTGSREDFQLARDLVIEKELQEKIEILVEWLVEKLNQCRLQLQLHKVIWD. 211
197 6.000e-45UniRef50_G0VPJ7 7-carboxy-7-deazaguanine synthase n=19 Tax=Bacteria TaxID=2 RepID=G0VPJ7_MEGEL  ali  24  4...............SLCVNEIFDSIDGEGKKAGQLATFIRLCGCNLRCSYCDTAYA---------------FNEGQHMDIADIIAQVSY--------PNVTLTGGEPLCQDIHALLEGLK--GHSVNIETNGSMDIEPYFKWFTVDYKSLSSDMANRMENFEKLRPQDVLKFVVGDEADLKCAVYVVFGKIEPRRIVEFMKE--NRLTDWHMQLQLHKFIWNP 205
198 6.000e-45UniRef50_A0A1F5UC85 7-carboxy-7-deazaguanine synthase n=3 Tax=Candidatus Firestonebacteria TaxID=1817802 RepID=A0A1F5UC85_9BACT  ali  25  4...............KGFLDEIFVSWQGEGAFAGVRQIFIRFALCNLECSYCDTAAAGEIK---ESFSAFGKRKINNPVSIDDVLKIV---KGFNSHVHSVSLTGGEPLVQGEFLLAKGLKKSGFKVYLETNGTLSILPFTDVVAMDIKLPSASGQKGLWKLKLAGKKAFVKIVISDKAKNRIIILQPEYRSNIRKVIKLIDKCFKSGVDIRLMPQIHRYIGI. 231
199 7.000e-45UniRef50_A0A2E2UZG8 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Gammaproteobacteria (miscellaneous) TaxID=33811 RepID=A0A2E2UZG8_9GAMM  ali  22  1..............MKLIVNEIFYSIQGESLSSGLPTIFIRLTGCPXRCQYCDTSYA---------------FTEGKKKTFEKIIEEIKNYX-----CTNVTITGGEPLSQKNTDFINLLVSDSYNVSIETSNAVSIKNINDVIVXDIKTPDSNEKNIIENYKFLKECDQIKFVICSKDDYQWAKIIMSPSFGEMDIQVLAXFMLKDNLPARLQTQLHKLIW.. 207
200 7.000e-45UniRef50_A0A1I2Q5A2 7-carboxy-7-deazaguanine synthase n=18 Tax=Firmicutes TaxID=1239 RepID=A0A1I2Q5A2_9FIRM  ali  22  3...............KYKVVEKFVSINGEGQKAGQLAVFVRFCGCNLNCTYCDTKWANVPDAKFEYE------------TADEIIKNIKDTK-----IKNVTLTGGEPLAQPNELLEKLSEEKELSVEIETNGSKNIEELKKLVTLDYKLAGSGMEKFMDNYEFLEQKDTVKFVCSNRVDLEKAKEIIDKYNLTSKCKAEIVDFMKENNNVNLQLQMHKFIWDP 217
201 7.000e-45UniRef50_S0ATY6 7-carboxy-7-deazaguanine synthase n=7 Tax=Ferroplasmaceae TaxID=90142 RepID=S0ATY6_FERAC  ali  23  1................MYINEIFLSIQGEGLYSGEKMVFIRTEYCNLRCSWCDTKYS---------------FYEGKEMSIDEIVES-ARNINSGHGASWICLTGGEPLLQKDISVLVDRLSEEYNILLETSGSLNIGRFLPNHVIDFKLPSSGMYRKFNNISYMEEGDYIKFVVNDLNDFKNVKIVVQPVYGT-DIKVLADAFIDKAPNARLMLQEHKYI... 207
202 8.000e-45UniRef50_F6CQX8 7-carboxy-7-deazaguanine synthase n=18 Tax=Firmicutes TaxID=1239 RepID=F6CQX8_DESK7  ali  25  2............SPPVAPLVEIFSSIQGEGIWVGCRQIFLRFAGCNLACSYCDTPRGIPHYCRWEARPGSREFLLPNPLTAQEVALMIRKLEPAAH--HSISLTGGEPLLHTSFLLELIPLLKGTRIYLETNGTLPILPLVDIIAMDIKLP----GTANINPCWQEHRAFLKLARGKHVFVKLVVDEDSKPEEIERALDLISRALERLTDVRVIPQTHKFLG.. 244
203 8.000e-45UniRef50_A0A2E3IYN1 7-carboxy-7-deazaguanine synthase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E3IYN1_9BACT  ali  26  9..PAYSHPIWRDSGEPLEINEIFYSIEGEGLRVGQPTTFIRLAKCNLRCFFCDT-----------------EFDTFSEMSIAEXLQEV-----RHHTASWISLTGGEPLGQNITPLCRNLVDAGYRIHIETSGTLDASEELDDLIEHWTVSPKHALRRISELKYIVGKAFREDVVEDRAEYIY----LQPESSKPEYIHKCLEILARHPNWRLSCRIHKMLHLP 210
204 8.000e-45UniRef50_A0A0S8DY59 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Candidatus Omnitrophica TaxID=1047005 RepID=A0A0S8DY59_9BACT  ali  23  1...................MEVFSSIQGEGIYAGQPQVFVRFYGCNMNCAYCDTP----------------SEGIAQETTVKSVMDAVSD-SNRDKSIRTVSLTGGEPLLYSLKILIPNLRRQGYKIYLDTNGTLPIIDLVDIVAMDVKLPSSTDKSFWAEHKEFKPKDFVKAVITSRTDIPFVLQPASRFRDFKDVPEIAKAANSRLRDVRIIPQVHKIWGL. 223
205 9.000e-45UniRef50_A0A1F9XAE2 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1F9XAE2_9BACT  ali  23  1..............MTLPVSEIFFSYQGEGIYAGQPQVFVRFAGCNLRCRYCDTPSTQ------EIKTNHVRLGATQLLNQIRALAQKHFIGPLRVFPPMVSFTGGEPLLHALRALLPALKKEKFLVYLETNGTLPVARWVDIVAMDIKLPSACGKNCWSAHSRFRRKAFVKIIVTAGISHKIPVILQPPAPVHGQSGAWLAVAGSYLKDVRVVPQLHKLWHV. 239
206 9.000e-45UniRef50_C9KKI3 7-carboxy-7-deazaguanine synthase n=29 Tax=Selenomonadaceae TaxID=1843491 RepID=C9KKI3_9FIRM  ali  24  7.................NLIEIFSSIQGEGKYVGCRQVFVRLEGCNLDCSYCDTPGSHPACQVETAAGSRTFATIKNPMTASETAAVIANLL-REVPHEAVSFTGGEPLLHAAFILQLRALGQPCKVFLETNGTLSILDITDIISMDIKLPSIVSRPQWEAHARFLELAYVKLVVSAKEEFEFIIQPVTPYGSPEKILACQSHALKHLKDVRVIPQTHKMIG.. 249
207 1.000e-44UniRef50_N9XJV3 7-carboxy-7-deazaguanine synthase n=4 Tax=Clostridium TaxID=1485 RepID=N9XJV3_9CLOT  ali  21  1................MNVVEIFQSIDGEANRAGNLTNFIRLAGCNLRCNYCDTDYALN-------------KTDGKEMSINEIISKLDKDIKN------ITLTGGEPLWNEDKPLLKELVSNGFNVSVETNGSINLKNYIKSFIVDYKSPSSNMEKDMENFNILRDIDCVKFVVGSLEDLKKAEIFVSPVFGEIEPKEIVEFLLKRKLKVRVQIQMHKVIWDP 213
208 1.000e-44UniRef50_A0A1F4TP31 7-carboxy-7-deazaguanine synthase n=5 Tax=Candidatus Saganbacteria TaxID=1703751 RepID=A0A1F4TP31_9BACT  ali  24  5...............QAQLCEVFNSIQGEGLYVGERQTFVRFAGCNLSCQYCDSPQALTIPKEFKVELVPGKKSFQNPVSVSQLIEIIKSLDKPKGMTHSLSLTGGEPLLQIDFLLPEFKKELKLPIYLETNGVLPVVENIDIVAFDLKLPSATGLSPYWKEHQKLVEVFVKIVLIAGIDEKIPLVLQPHRPNAEQILAFQAIAKRKLKNVRVIPQTHKIMGI. 252
209 1.000e-44UniRef50_A0A1F5YUC8 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Glassbacteria bacterium RIFCSPLOWO2_12_FULL_58_11 TaxID=1817867 RepID=A0A1F5  ali  22  10................LTVCETFVSLAGESGWQGLVSTFIRFSGCDVDCAWCDTAYA--------------RQEKGTPVSIGDIMSICRANRIRK-----VVLTGGEPLLQEELPLCRALLEEGFDVQVETSGTRDKLDSLVMKVLDIKPPSAKTEKGWGNLDLLGKRDEIKFVLADRKDYDWCKVLFSTVAGSLDPAELAGWMIEDGLSVRLQLQLHKLLW.. 214
210 1.000e-44UniRef50_A0A1G0A6S2 7-carboxy-7-deazaguanine synthase n=3 Tax=unclassified Euryarchaeota (miscellaneous) TaxID=115531 RepID=A0A1G0A6S2_9EURY  ali  21  1MAVGSVGTAKPGE--TFLVSECYPTIQGESSLVGTPTIFVRLYGCNLRCRWCDSMHAVEG-------------GEFTERSVRDVTMEVVRLSTRFRGIHHVCWTGGEPLLQGRSIAAIRELPPDFVHSIETDGEVDLGPFDVRYVMDVKCPGSGMRRAFENLRLLRRTDEVKFVILDRGDYDFARRVLADHPVPADPAALASWILEDRLDVRLQPQLHKFLW.. 244
211 1.000e-44UniRef50_C9RPJ9 7-carboxy-7-deazaguanine synthase n=18 Tax=Fibrobacter TaxID=832 RepID=C9RPJ9_FIBSS  ali  20  1................MKVCEIFKSIEGEGIRMGQAAVFVRLHGCNLRCSYCDSMYAVEGP-------------DFKQMSVGEVLAAVEMYRNESG-VKCVTLTGGEPLIHEGVELLTAFSDAGFEVNIETNGTVPCKWQLPFYTMDWKCKSSGMSARMENIISLGKNDVLKFVVGSNMPHIFISPVWGELTNEQIVNWMVGSKVMTQNNARFQVQLHKIVWDP 219
212 1.000e-44UniRef50_A0A2D6EA69 7-carboxy-7-deazaguanine synthase n=3 Tax=Bacteria TaxID=2 RepID=A0A2D6EA69_9BACT  ali  25  18.GSGPALPEGADTVSTLLVHEIYRSIQGESTRAGRPCVFVRLTGCDLRCAWCDTEHA---------------FHGGTRRAVEDIVAEALGL-----GEGLVLVTGGEPLLQEAVDLLRQLLDAGREVMIETGGHRDIRGVDERVVVDVKTPSSGESGKVANFDPPRKTDEVKFVIADRADFDWSLGRIRDFRLEGRCTILAEWLLASGIEATLQLQLHRILW.. 236
213 1.000e-44UniRef50_A0A1Q7RR49 7-carboxy-7-deazaguanine synthase (Fragment) n=1 Tax=Acidobacteria bacterium 13_1_40CM_2_68_10 TaxID=1803445 RepID=A0A1Q7RR49_9BA  ali  23  1MNVAA--LARDRTATVLTINEIFHSVQGESRHAGRPCVFVRLSRCNLRCTWCDTAYA---------------FEEGSDMPVGAVLARVAAF-----GTRYVLITGGEPLLQEGVDLIGELCDRGFEVAVETGGSLDLAPLDPRVVMDLKCPGSGMKNRLENIDLLKPADEVKFVVGDRADYDWARVLLSPVHGVLQPRRLAEWILTDR................ 204
214 1.000e-44UniRef50_A0A0J6CTA4 7-carboxy-7-deazaguanine synthase n=3 Tax=Bacillales TaxID=1385 RepID=A0A0J6CTA4_9BACI  ali  22  6.......LPERSEYMKLPMVEVFETVEGEGTRAGFPTVFVRVFHCNLRCSWCDTPYS---------YAPDKAEYTG---SIEAIVDQISQYKSRQ-----ICFTGGEPLIHREKSMALLQAMVDLPIHIETNGAIDLTPYKVRFVMDYKLPDSGEQHRMENFNLLDTQDEIKFVIGSDEDFTVATDVVAKHHDKGQVLKLVEKILEGLSKVKLSMQLHKIIWDP 237
215 1.000e-44UniRef50_A0A2E8RY56 7-carboxy-7-deazaguanine synthase n=1 Tax=Myxococcales bacterium TaxID=2026763 RepID=A0A2E8RY56_9DELT  ali  21  1.....MTLPGAQRNLAMNVIEIFHSIQGESTLTGIPTTFVRFARCNLRCVWCDTPYS---------------FGGGTPMTQEEILGEIK-----TAGLQHICLTGGEPLLQQDLPFCSRLLAEGYVVSIETGGHMDISVLPEGVICDIKTPGAFGNAHEENIKHLTSFDEVKFVVMSLEELPWVKSVISPVHGTIELEALARFLVEEKLPARLHLQMHKF.... 226
216 1.000e-44UniRef50_A0A1B2HE91 7-carboxy-7-deazaguanine synthase n=6 Tax=Pseudonocardiales TaxID=85010 RepID=A0A1B2HE91_9PSEU  ali  19  1.......MPPGRVEGSAILTEKFESFQGEGPWTGQRCVFVRFSRCNLRCSYCDTPESWDWNRYNPAEVSDR-------VPVTELVSWV-----RERGVDMMVITGGEPMLQQPAMIALARGLADVRVQVETNGTIAPTPELASVVDLWVVSPKLANSGMTYSTRIKADALSALVATGRAVFKFVVT------EPGRDLDEIAQLVEEHRPVWVMP......... 192
217 1.000e-44UniRef50_F8FPI8 7-carboxy-7-deazaguanine synthase n=43 Tax=Terrabacteria group TaxID=1783272 RepID=F8FPI8_PAEMK  ali  26  21.............DIRLPMVEIFETVEGEGTRAGFPTVFIRLFGCNLRCTWCDTKYSY------------PPAEAEFVMTIGEIVQEAAKYKA-----KHICFTGGEPLLYGDAALIEALVAAGRYTHVETNGAVDLAPFLERIVMDYKLPDSGEQEKMGNLALLRPQDELKFVIGSERDFFTAVQVLKDYPETMPPVKLVGLMLEHGLHVKLNMQLHKIIWDP 239
218 1.000e-44UniRef50_J9Z823 7-carboxy-7-deazaguanine synthase n=14 Tax=Bacteria TaxID=2 RepID=J9Z823_LEPFM  ali  22  1................MKITETFRSIQGESRYSGWPCFFIRTTGCPLRCRWCDTTYS---------------FYGGEERTVDSLVGEA-----VSSGTSLVEITGGEPFVQPELPLCQKLLDLGKTVLIETSGGFPVPSGLCRLIVDLKPPGSGMEAWMENFAELGTEDEIKAVLTGREDFDWRVPVFSPVFGECDPRELARWVLDSGLPVRVQIQLHKILFDP 207
219 2.000e-44UniRef50_A0A202DZD0 7-carboxy-7-deazaguanine synthase n=3 Tax=Bacteria TaxID=2 RepID=A0A202DZD0_9BACT  ali  20  5...............QLKINEIFYSIQGESYLSGLPCIFIRLTGCDLRCTYCDTKYAY---------------YDGQFMEFSEIIIKIKEY-----PCYNVLLTGGEPLLQKNTKLAQKLIDLGYKVAIETSGNHDISVLPNEVIMDLKTPGSGKKNDYKNISKLTSKDEIKFVVVNNEDTHWAIKQIKENNLDQRCPSIADEVLNSGRKIRHQFQMHKVIW.. 208
220 2.000e-44UniRef50_A0A2A5FH00 7-carboxy-7-deazaguanine synthase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A2A5FH00_9BACT  ali  28  6...............KYPIMEVFPSLQGEGRYSGVQAYFIRLAGCDVGCVWCDVKESWN-------------AGDYKEVTVRDIVGGAIDSK-----IAMVVITGGEPCMYDLNPLTEELKSAGLRVHLETSGAYPIRGEFDWITLSPKCLYESYGRA----------DELKVVVANKHDLTWLLYLQPEWSKKEKVTEMMLDFLKTEQGWSLSIQTHKYLGI. 203
221 2.000e-44UniRef50_A0A2D7BY97 7-carboxy-7-deazaguanine synthase n=19 Tax=unclassified Euryarchaeota TaxID=33867 RepID=A0A2D7BY97_9EURY  ali  34  4................YPIVEIFHSVQGEAFHAGIPHVFVRFGNCNLRCEWCDTDFL-----------------TYXEMDLDDILSEVLSY-----XCSRVIFTGGEPCLQDLDTIGSELKKHNITLSVETNGTIPVPEIIDWICVSPKSNVSIKQRTGDELKVVYCGQDLSMYDELKQGFEHHYLQPCSVEENGKNFAVVENLVKESPGWRLSLQTHKWMGV. 197
222 2.000e-44UniRef50_A0A2G6P7I2 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A2G6P7I2_9BACT  ali  25  2................IKINEIFYSLQGESVYAGLPCIFVRLTGCNLRCSWCDTEYS---------------FYNGDYLTLNEIEKKIKSF-----PSKLVEFTGGEPMLEKIKPLIDSLLSEGYTILMETNGTISIKNLDKRVIVDYKTSGESGKFLLENLKFLDKKDQIKFVVSTKEDFE---DLLLFYGSNRENIEIAKMIIDSKINFRYQVQLHKIIW.. 207
223 3.000e-44UniRef50_D4W838 7-carboxy-7-deazaguanine synthase n=13 Tax=Bacteria TaxID=2 RepID=D4W838_9FIRM  ali  23  2................YQVIEKFISIDGEGPCAGQLAAFIRFKNCNLRCDWCDTCYSYDGSVE------------GENLSPLEIYHFVKENKVN-----HVTLTGGEPLIQPQIEVLILAADKELTIHIETNGSVNISKSNVVFILDYKLPNSLMQSRMDNFKWVTKTDVYKFVIASQEDLKVAHEVIREQGLLERCLSLIVDYMKDHNDVRLQLQLHKYIW.. 215
224 3.000e-44UniRef50_A0A2A5DFR8 7-carboxy-7-deazaguanine synthase n=5 Tax=Bacteria TaxID=2 RepID=A0A2A5DFR8_9BACT  ali  21  3...............TLMINEIYHSIQGESSFVGLPCVFIRTMGCSLRCSYCDTEYA---------------FYDGQEKEINWILKEVQKFKT-----KLFLLTGGEPLDQSNLILLTLLCDQGYTACIETGGHLDIIDERVHIILDVKTPSSKMKNHYKNLDIITKKDEVKFVVGNEDDLNWSLILISPVFGEVDYQWLAQRIIESNKKIRLQIQQHKIIWGP 209
225 3.000e-44UniRef50_E9S9P1 7-carboxy-7-deazaguanine synthase n=1 Tax=Ruminococcus albus 8 TaxID=246199 RepID=E9S9P1_RUMAL  ali  22  5................FSLAEHFISINGEGQRAGELALFLRFTGCDLRCVWCDTLWAVPKDAPH------------KDKDLRSLLDIARD--AVSHGVRNVTLTGGEPLMQKIVRLFEALLDMGLRVEIETNGSVALAPFIPDFNMDYKLPDSGMESRMDNISLLQANDTLKFVCASHRDLKVYFSPVFGKIEPADMVEFIKE--KGLGEVRLQLQLHKFIWDP 217
226 4.000e-44UniRef50_A0A0L6Z6T3 7-carboxy-7-deazaguanine synthase n=85 Tax=root TaxID=1 RepID=A0A0L6Z6T3_9CLOT  ali  20  1..............MNFKIVEKFVSVNGEGPLCGQLAVFIRFSGCNLNCSYCDTAWANKIDI------------PYELMTDKDIYDYIK-----STGIKNITLTGGEPLIQEIELLKRLSKDRELHVEIETNGSVSHIENPPSFTMDYKLPSSNMENKMDNFKYLSKKDTVKFVSGSIEDLERAKNLIDTYSLVDRSMDKIVEFMKYNKGVNLQLQLHKVIWDP 216
227 4.000e-44UniRef50_A0A0X8WXT6 Pyruvate formate-lyase-activating enzyme n=6 Tax=Bacteria TaxID=2 RepID=A0A0X8WXT6_9CYAN  ali  20  2.............SITGRIHETCGTVDGPGLR-----VVVFTQGCPLRCLYCHNPD-------------CREISGGTEVTADEIVAEIQKYRSYIRPPGGVTISGGEPLMQPEFEILQQCKALGIHTALDTSGYHPVLEFVDLVLLDIKSFNPSIYTQVTSVSLQPTLDFAQYLSDCRKPAWIRFVVVPGLTDNLDNVSGLAQFVARLKNVRIIIPFHKM.... 202
228 4.000e-44UniRef50_A0A1S8NBM5 7-carboxy-7-deazaguanine synthase n=6 Tax=Clostridium TaxID=1485 RepID=A0A1S8NBM5_CLOSA  ali  22  2................FNIVEKFLSIDGEGPTSGEIATFIRFQGCNLRCSWCDTVYSW-----------------GKESTNEKLSANEIYQYIKENGATNVTLTGGEPLIQEDELLNILNKDENLMVHIETNGAVNIKGGNISYIVDFKLPSSNMSMDMNNLKIVESSDVYKFVVGSSEDLNMAYDIIKKYDLTSKCLKDIVEFMKKLNKVRLQVQLHKVIWD. 216
229 4.000e-44UniRef50_A0A258V7L0 7-carboxy-7-deazaguanine synthase n=1 Tax=Bdellovibrio sp. 28-41-41 TaxID=1970323 RepID=A0A258V7L0_9PROT  ali  25  2................LKINEVFYSIQGESSWVGHPTVFVRTTGCNLRCAYCDTKYSY---------------YEGEFQELGTLLNEIAK-----HKTKFVCLTGGEPLLQKEFPLMDTLVSQNYLVSLETSGSKSIENVNPKVILDVKTPDSGASFLISNLEFSNELTEFKFVICSEKDFEWFTVLYSPSYGAVSERWLAERILARYSIARMQIQLHKKIW.. 205
230 5.000e-44UniRef50_D2QQX5 7-carboxy-7-deazaguanine synthase n=38 Tax=Bacteria TaxID=2 RepID=D2QQX5_SPILD  ali  34  15...........QSTIALPVMEAFYTIQGEGAHTGRAAYFIRLGGCDVGCHWCDVKESWDADAHP-------------KQSIDALVKGAL-----QYPGRLAVITGGEPLMHDLTALTEALQVAGFKTNIETSGVCQVTGSWDWICFSFKKPNPAIYEKADELKVIIYNQSDFAFAESFVPYDCKLFLQSEWGRSNEMLPRIVDYVKDHPQWQISLQTHKFLNIP 216
231 5.000e-44UniRef50_G7WDT0 7-carboxy-7-deazaguanine synthase n=18 Tax=Peptococcaceae TaxID=186807 RepID=G7WDT0_DESOD  ali  21  2..............PQLPVTEIFSSIQGEGPYVGVRQIFLRLPKCNLRCPYCDTPTALSQYMRMETDPGSGAFEKKNPIPLDSLSEMLRSYD--FSIHHSLSITGGEPLLWDLAYLLPLLKDKNIKIYLETNGTLPILPWVDIISMDIKLPF--ANQTFWNVHELHKEVFVKIVVNEDTDLILRVVTPTGVIKAPKSLQLIQWLLRELSMVRVIPQTHVFMG.. 241
232 6.000e-44UniRef50_A0A256ZBJ6 7-carboxy-7-deazaguanine synthase n=1 Tax=Thermoplasmatales archaeon ex4484_36 TaxID=2012523 RepID=A0A256ZBJ6_9EURY  ali  24  38...........GRRVKVRVAERFLSLQGEGLTTGVPTYFIRLSGCNLRCSWCDTPYAFEGGEEVEVASVVEE--------------------ALSSGAPRVCITGGEPLLQRAVELLVKILERGVGVDLETNGTIPLLPVLELISMDVKCPSSGEKTHWENLKLLRESDQLKFVVADEEDILYAERVLKQHPTRAELLALAELFLRESLRARFLLQMHKYIW.. 262
233 6.000e-44UniRef50_UPI0007DE550C putative 7-carboxy-7-deazaguanine synthase QueE n=3 Tax=Clostridiales TaxID=186802 RepID=UPI0007DE550C  ali  21  1..............MGFKVVEKFVSINGEGTRCGQLAIFIRFAGCNLNCSYCDTLWA------------NEKDVFYEVLSSNDIYEYIKA-----KKIKNVTLTGGEPLMQKIELLKLLSEDNEINVEIETNGSILLNKFFNIFTMDYKLPSSSMENKMDNFKYLTKKDTVKFVSGSIGDLEKAKEIINRYDLVDKNFDTIVEFMKNNKGVNLQLQLHKIIWEP 216
234 6.000e-44UniRef50_A0A223V1T3 7-carboxy-7-deazaguanine synthase n=9 Tax=Bacteroidetes TaxID=976 RepID=A0A223V1T3_9FLAO  ali  28  3...KKDTMALVDKGLLLPLMEEFYTIQGEGFHKGTAAYFIRVGGCDVGCHWCDVKESWNAETHP-------------PTNIELIVENAAKYS------DTIVVTGGEPLTWDMGPLTDRLKSKNLKTHIETSGAYPLTGDWDWICLSPK------KNKLPVGRIYDEAHELKVIVYNKHDLIFALYLQPEWSVRDKVTPMIVDYVMKNPKWKVSLQTHKYLNIP 210
235 6.000e-44UniRef50_A0A1G9W228 7-carboxy-7-deazaguanine synthase n=11 Tax=Bacteroidetes TaxID=976 RepID=A0A1G9W228_9FLAO  ali  31  33...........DKGVMLPLMEEFYTIQGEGFHKGTAAYFVRIGGCDVGCHWCDVKESWNAETHP-------------PTAVENIVENAAKYS------DTIVITGGEPLTWDMGPLTSALKAKNLKIHIETSGAYALTGIWDWICLSPK------KNKLPEGKIYDKAHELKVIVYNKHDLIFALYLQPEWSVRDKVTPLIVDYVMQNPKWKVSLQTHKYLNIP 232
236 6.000e-44UniRef50_B0R9W6 7-carboxy-7-deazaguanine synthase n=103 Tax=cellular organisms TaxID=131567 RepID=QUEE_HALS3  ali  25  1MPVSETTASNGGDGPALPINELFYSLQGEGKLAGTPSVFVRTSGCNLRCWFCDSYHTSWEPTHAT-------------MSVDDIIAEVQSYE----HADHVVLTGGEPLLHDDVVLLDRLAALGYHTTVETNGTIHRDAPIDLASVSPKLASSGEWAARHDARRIDVATLGALADDYDTQLKFVVTDPSDMPEIESLLAEIRTATDTREDVVLMP......... 216
237 7.000e-44UniRef50_A0A1W9TDZ0 7-carboxy-7-deazaguanine synthase n=2 Tax=Planctomycetes TaxID=203682 RepID=A0A1W9TDZ0_9BACT  ali  26  1................MIVNELFYSLQGEGSLAGVPSVFIRLAGCPLRCCWCDTKYAWD-------------ETAGREMSCEQVLEALD-----GHPTRHVVLTGGEPMVHEGVSLAAAIREKGYHLTIETAGICFIEGLADLMSISPKLSNSLPENADRPAERLNLGVLRQLIAAYDYQIKFVVDEPDDLNEIADILEKLDEL--DLYSIYLMPQ........ 182
238 7.000e-44UniRef50_A0A2H0PJP2 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A2H0PJP2_9DELT  ali  37  3...............TYKINEIFYSLQGEGVRAGTANVFIRFSDCNLRCSR--NKEGFD---CDTEFIS------GTQMNLDQILSQARSLSA---TCDWVILTGGEPSLQIDDSLLDALHTAGYKIAIESNGLRELSSKIDWICISPKTASSLRQKTAHELKYVRALGMKIPNPSIKAEHYLISPAFEVDHLPSENLEHCLNLIRDNPKWRLSVQQHKIWKV. 197
239 7.000e-44UniRef50_A0A257M167 7-carboxy-7-deazaguanine synthase n=3 Tax=Verrucomicrobiae TaxID=203494 RepID=A0A257M167_9BACT  ali  26  11....................EIFHTLQGEGVSAGLPAVFVRSSRCNLHCHWCDTDHTWNFPWTHEKDAVPGYAKHRKEMSPSVIADLVAAY-----PCRRVVLTGGEPLLQQDLIRALREIDPGYVFEVETNGTLAPTAEFVQAVDQFNVSPKLANSGMDESLRLKPEALKALAATGKAWLKFVLTAPSDLSEIEAIAERVADLCREN-GYRFSDRLHVRLW.. 244
240 7.000e-44UniRef50_A0A1F9VGS6 7-carboxy-7-deazaguanine synthase n=1 Tax=Elusimicrobia bacterium RIFOXYA12_FULL_49_49 TaxID=1797954 RepID=A0A1F9VGS6_9BACT  ali  24  1........MKLKPESSAKISEIFFSFQGEGLFAGKPQVFVRFSGCNLSCSYCDTYH-----------------KSGKDMTPRAALLEILGLIRNHFFKPSVAFTGGEPLLRADFLVLPELKKAGVKVYLETNGILFVSGYVDVVAMDIKLMPDCKNSHRQFLKACRKKAFVKIVLTDKAEFVKALSLIAGISKKARLYEFTRLAREKLNNVYVLPQMHKIWNI. 237
241 8.000e-44UniRef50_A0A1H3LR26 7-carboxy-7-deazaguanine synthase n=93 Tax=Bacteria TaxID=2 RepID=A0A1H3LR26_9FIRM  ali  22  18.........EKSDTITYKVVEKFVSINGEGQKAGQLAIFIRFQGCNLNCVYCDTKWA------------NQKEAKYHLMTAQQIIDYIK-----STNVKNVTLTGGEPLRQENIMLEKLSLIENINVEIETNGSVSIIKNSPSITLDYKLPDSNMEKYMDNYDFLESKDTVKFVCSSINDLKKAKDIIEKYSLTSKCKAEIVDFMKEHNDINLQLQMHKYIWDP 238
242 9.000e-44UniRef50_A0A2E7D1S7 7-carboxy-7-deazaguanine synthase n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7D1S7_9PLAN  ali  24  11....................EIFYSIQGEGKTIGRPSVFVRLSLCNLYCYWCDTAYTWNWQGTAFPHIGDTPAKFTKENEIVTLDAADVCERIHQFDCRNVVITGGEPLLQQDELLILKKIDQSYQFEIETNATLIPIDDIDRASVQYNVSPKLSNSRVESARRLVDDALKWFAACSRSHFKFVIETPDDLV---EVQELVEQYEIDLDRVYLM.......... 207
243 9.000e-44UniRef50_UPI000488CD1E putative 7-carboxy-7-deazaguanine synthase QueE n=1 Tax=Lachnospiraceae bacterium YSB2008 TaxID=1410633 RepID=UPI000488CD1E :_  ali  23  2..............PEYRVVEKFISINGEGQRAGELAVFIRLAGCNMRCSYCDTLWALEKDVPFVSK------------TEEEIVSYLQ-----SAGVKNVTLTGGEPLIHKDDILIRSIIDAGFRLEIETNGSIDIRRFDERYTVDYKCPGSGCESFMKNFENVGKNDTVKFVVTDMKDLDRMREVVSEYYLTAKTKADVADYMIEHKDIRLQLQIHKYIWDP 213
244 1.000e-43UniRef50_A0A0Q0XQ71 7-carboxy-7-deazaguanine synthase n=11 Tax=Bacteroidetes TaxID=976 RepID=A0A0Q0XQ71_9FLAO  ali  28  11...........DKGLMLPLMEEFYTIQGEGYHKGTAAYFIRVGGCDVGCHWCDVKESWNAETH----------------PPTQIASIVDNASNYS---DTIVITGGEPLTWDMGPLTAALKEKKLQTHIETSGAYPFTGIWDWICLSPK------KNKLPEEEIYAVAHELKVIVYNKHDFIFALYLQPEWSVREKMVPLIVDYVMKNPKWKVSLQTHKYLNIP 210
245 1.000e-43UniRef50_A0A2H5ZN68 7-carboxy-7-deazaguanine synthase n=1 Tax=bacterium HR30 TaxID=2035425 RepID=A0A2H5ZN68_9BACT  ali  24  1..............MDGYLSEIFVSFQGEGARVGERHLFVRLAGCNLRCRYCDTPDSLERRPLWYYHDPATGQTSPNPVSAGELLRLVADLCEQDPSLQMIALTGGEPLLQAKFLEFLVGTKLSLPVLLETNGVLPVLPSVHVISMDIKLPSNAGERAFWDEHR----AFLELAKSRECYVKVLIDWNTSVADVEQAARIVSQVARHHESVRVLPQVHKVLGIP 246
246 1.000e-43UniRef50_A0A2M7S296 7-carboxy-7-deazaguanine synthase n=4 Tax=Bacteria TaxID=2 RepID=A0A2M7S296_9BACT  ali  24  6...............SMKITEIFFSYQGEGIYLGMPQVFIRFAGCNLRCRYCDTVESQNAD-------------EGMKLTTDEVIDEILKTSTPSKKVKYVSLTGGEPLLQFLLDLIPKLKRNRLKIYLETNGTLPVIDLVDIVAMDIKLPSDCKRNFWQGHRQFLKKVFIKLVLTKNTENKEVYKSINLIKSIDRNIPLVLQYAQQNLKVFLTPQMQKYWQI. 236
247 1.000e-43UniRef50_A0A2E0APB8 7-carboxy-7-deazaguanine synthase n=5 Tax=cellular organisms TaxID=131567 RepID=A0A2E0APB8_9CYAN  ali  30  4................FAVVETFHSLQGEGFHSGRSAFFIRLAGCSVGCSWCDTKQSW-------PEAAHPQRSSGSL--------ALEASQAIQNGAAFTVITGGEPLHHDLKPLTTALKHATHPIHLETSGVDPLSGCLDWITLSPKP------HHPPRRDVLLRCDELKVIVHTATDLQFAVLLLQPGWNSNSGQALVVDYVKHHPQWRLSLQTHKWLGV. 201
248 2.000e-43UniRef50_A0A2E8WMB4 7-carboxy-7-deazaguanine synthase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E8WMB4_9BACT  ali  26  10..ASEHSRPVWNDGQILQINEIFYSIAGEGARVGQPTIFVRLAKCNLRCFFCDT-----------------EFDSFTEMSLQEIIDEV-----RIHTGEWVSLTGGEPLGQNIAPLCEALRRLGYRLHIETSGSLPPQTELFDLIEHWTVSPKRKFERITELKYVVGKAFREDVEEDRSELIY----LQPESSKPEYIHKALEILQRHPTWRLSCRIHKMLHLP 211
249 2.000e-43UniRef50_A0A1Q7UWZ5 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Acidobacteria (miscellaneous) TaxID=305072 RepID=A0A1Q7UWZ5_9BACT  ali  29  1................MQITEIYKSLQGESTYAGMPCVFVRLTGCNLRCVWCDTEYS---------------FYGGKKVTPEQVFDEVESLSL---APGLVEITGGEPMLQELVPLMQRMHEAGYKVLLETSGERPLERVPVVKIVDVKCPDSGEGDHIENLETLQPHDEVKFVISGRGDYEFA........................................ 156
250 2.000e-43UniRef50_A0A1W9P2R4 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Aminicenantes TaxID=910038 RepID=A0A1W9P2R4_9BACT  ali  27  1..........MPQPPTLKIKEIFASIQGEGLRCGEPTFFIRLAGCNLRCPWCDTKYAW---------------RGGKIYTVDEILHQIEQL-HLKWPINWVCLTGGEPLLQDIKDLVLVLKKAGFCLQLETNATLYQNLAIDWWTISPKPPDYFFQN-----SFLTKAKEIKLVVSSELNLPIIKNIREAFPSTPIILQPQSNYLWSRKKARLGLQLHKI.... 205
251 2.000e-43UniRef50_A0A1I2MC32 7-carboxy-7-deazaguanine synthase n=14 Tax=Bacillales TaxID=1385 RepID=A0A1I2MC32_9BACL  ali  23  3...........PKEITLPLVEIFQTVEGEGGKAGFPTTFIRLYNCNLRCTWCDTPYSYAPHP------------PEKMLTVGEILEQVKRW-----GNRHICLTGGEPLLYRDKALALLQELAPLPIHIETNGAIDLLPFHRWFIMDFKLRSSGERDKMSNFLHLTDRDEIKFVISDRAEFDEALSVVESAVRRGQILRLVSWLLQQRRDIRLNLQTHKYIWDP 227
252 2.000e-43UniRef50_A0A255I1U4 Pyruvate formate-lyase-activating enzyme n=5 Tax=Clostridiales TaxID=186802 RepID=A0A255I1U4_9FIRM  ali  17  2..............IKGRVHETFGTVDGPGIR-----YILFLQGCPLRCKYCHNRDTWD-------------VKSGKEYTTDEIIADASKYASYMKFGGGITVSGGEATLQPEFELFKKAKANQIHTCLDTSGFVPVLDNTDLVLLDLKHMIDEKSKDLTGVGIEKAIKLAKHLDERNIPVWIRHVLVPGITDDTENLEELAKFVSTLNNVRLSLGIHKWMGI. 212
253 2.000e-43UniRef50_A0A1G1PG12 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Candidatus Omnitrophica TaxID=1047005 RepID=A0A1G1PG12_9BACT  ali  22  1.......MPTETLTTTARIIEVFSSVQGEGVFVGQPHLFVRFWDCNLKCAYCDTEY----------------RGPYTEMTRAELEGRVSELLVEQGPHEAVSLTGGEPLLWRQFLFLPWLRQMGQRTYLETNGTLPVLPWVDVIAMDLKPPSSTADRAVWHEHAAFLDVARRAVRPPNLFVKVVVTVVTAPPVAAQLHRWIRIARARLDDVRVIPQMHKVLGLP 241
254 2.000e-43UniRef50_A0A1V6CC85 7-carboxy-7-deazaguanine synthase n=1 Tax=candidate division TA06 bacterium ADurb.Bin131 TaxID=1852827 RepID=A0A1V6CC85_9BACT  ali  28  2................LDICEIFVSIQGEGWRQGTSAVFIRFYGCNLRCKFCDTRVA---------------FTKKQSMDEKEIVEIVRRLSRKYNNITNIIITGGEPYLQDFSNLVLQLKLSGFFVCVETNGTIWREIPLDWICVSPKKSAKKLLQQGYDKRFKDVANEFKYVITGKHDFSFIVILQPVNNDLKIALMIFKQIKKSMPNWFLRFQIHKLMGI. 201
255 2.000e-43UniRef50_A0A1F4UAF4 7-carboxy-7-deazaguanine synthase n=1 Tax=candidate division WOR-3 bacterium RBG_13_43_14 TaxID=1802590 RepID=A0A1F4UAF4_9BACT :_  ali  23  2............SVMGGYLREIFTSIQGEGIRIGRRQTFIRFLGCNLSCNYCDTPETQKMDGPFLHKKVVYS----NPVAVEQVIALIEE--------KEVSVTGGEPLLQIEFFLLQELKKKDICVYLDTNGTLPVIDLIDCVALDFKIPPKLWTEHEDCLSIAREKDFVKMVINENVAIIKRVLIIQPVFDINSILEIQKKALEQLPNVRIIPQMHKYLGL. 229
256 2.000e-43UniRef50_A0A2E0BZF9 7-carboxy-7-deazaguanine synthase n=1 Tax=bacterium TaxID=1869227 RepID=A0A2E0BZF9_9BACT  ali  22  12..............MKIMISEIFYSLQGEGIQIGIPTVFVRLFGCDLRCSWCDSMYAV----------------EGTDFSSLEINDVINTTLSYQ--CSNICITGGEPLLQLDVYLTEKLIEVDKRVILETAGXRKPPDIFEIVSMDCKCPSSGMKSDLKNLIXLKPKDQIKFVIADNDDYIFAKNIVKQNPFRAEIIEIADAVIKDXLKVRVLPXLHKDIW.. 219
257 2.000e-43UniRef50_A0A2G9YAZ0 7-carboxy-7-deazaguanine synthase n=1 Tax=bacterium (Candidatus Ratteibacteria) CG23_combo_of_CG06-09_8_20_14_all_48_7 TaxID=2014  ali  23  2..............PIAKINQVFVSIQGEGVFIGVPQIFVRFSGCNLTCKYCDVP----------------RELPEKEFTVQELCHVIATLNKKDGPVHSLSLTGGEPLIQADFLLLPYLKRKGFKVYLETNGTLPAKRWCDFIAMDIKLPSATGGKPLWEVHKNFLKESLTFCPAPKTFVKVVVTVIQPVVNAKKLLEFLRLTQKFLPSVRLIPPVHQFLGLP 234
258 3.000e-43UniRef50_A0A1F2WFV0 7-carboxy-7-deazaguanine synthase n=1 Tax=Actinobacteria bacterium RBG_13_55_18 TaxID=1797197 RepID=A0A1F2WFV0_9ACTN  ali  23  1................MYLHEIFPSFQGEGLLLGVRQVFLRLSGCNLACDYCDTTEARIKSDTFTPDAEGNKQTLPNPIDVEETARLVGELW--KPSMHSVSLTGGEPLLQAEELLLPLLKQQGMPIYLETNGTRYLLPHIDWIAMDIKLPSSQGGKDL----FAEHVRFLEIAAIANIFLKMVITPESGEDELDRAIRLHGIASAYFNDVRVIPQMHRLWGI. 239
259 3.000e-43UniRef50_A0A1F6PW02 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Melainabacteria bacterium GWF2_37_15 TaxID=1801606 RepID=A0A1F6PW02_9BACT :_  ali  20  1..............MQANITEIFSSIQGEGPYIGCRQIFVRFSGCNLRCEYCDTDH-----------------RPVKMLTCEELLQEINSLNIISH--HSISLTGGEPLVHSDFLSEFLPMLSDLKVYLETNGFRKIAPYVDIISMDIKLPFEAHEEFIKVARFFKKEIFAKVVVSENIDEEIRLIVLQPMDNKDKLISIQMNFLKDIKDVRVIPQVHKYMGL. 217
260 3.000e-43UniRef50_A0A2H5VFV5 7-carboxy-7-deazaguanine synthase n=1 Tax=archaeon HR06 TaxID=2035442 RepID=A0A2H5VFV5_9ARCH  ali  22  1..............MNIPISEIFYSIQGEGINQGKPAVFLRTYYCNLSCQWCDSKYTWENQIRAQE------GIDYISMNLEDIIENI-----RKYPCKHLVITGGEPLLHNLLNLVRKLKKMGYYIEVESNGTIKPLKELLSLVDCFNVSPKLSNSKLEEKVRIKEDVLKVFSLEDKVYFKFV---VCERKDLEEVESLVSKFNISKDKVILMP......... 189
261 3.000e-43UniRef50_A0A0G3WHL1 7-carboxy-7-deazaguanine synthase n=1 Tax=Endomicrobium proavitum TaxID=1408281 RepID=A0A0G3WHL1_9BACT  ali  21  16................APVYEVFFSYQGEGPYTGTPQIFVRFAGCNIKCNYCDTAYSIKISDNAKYYSSQELLAEIEKILKKMDCRGASRFAMTGTSKPSIAITGGEPLIHADFLFLPALKKYGFQVYLETNGTLPIISFCDIVSMDFKFQSECKKSFWKEHK-----EFLK-IAKDKVFVKCVVTKNTSLNEIKRSGQIIRELKKTLPNVLIMPQLHKILRI. 252
262 3.000e-43UniRef50_A0A0T5ZZF5 7-carboxy-7-deazaguanine synthase n=12 Tax=cellular organisms TaxID=131567 RepID=A0A0T5ZZF5_9BACT  ali  24  5.............EMTFQVSELFTSIQGEGEVIGMPSHFIRLYRCDLTCSWCDSKYTWLRQDQAVE------RKDYTSMSAEEILGWLRKE----PRAPLVTLTGGEPMLQPLLPLVAALDTRGYQVVVETNGLHRPEELVRYWAVSPKLKNAGMDIKWGPLDWLAKTQNLKFVICDPADLEFVILQPDGLADYETILRSVAEFVRDRYPYRVLPQLHRLLW.. 226
263 3.000e-43UniRef50_Q8KFK8 7-carboxy-7-deazaguanine synthase n=18 Tax=Bacteria TaxID=2 RepID=QUEE_CHLTE  ali  22  7................LNISEIFYSIQGESSFAGWPCAFVRLAGCGHGCRYCDTTYA---------------EEPGTAMTIDEIMHRVLAF-----DAPCVEVTGGEPLLQSGFGLLSALCDRHPVVLLETGGFLPVDRVDPRVIIDIKAPSSGVMEHNCAANNEPERFEFKIVVASEADYLWAKSYIAGHGILGKCLELAEWMLRDRLPVRMQLQLHKYIWNP 215
264 3.000e-43UniRef50_F0T104 7-carboxy-7-deazaguanine synthase n=2 Tax=Syntrophobotulus TaxID=51196 RepID=F0T104_SYNGF  ali  30  10................YPVHEIFDSIQGEGYWTGAAASFVRLQQCNLRCAWCDSKGTWEGKP--------------EKMTADEILAAVHSER--------VILTGGEPLLHDLTALLESLKAAGKKVHIETNGTQPWKPQEAWITVSPKLVQPSIKSKANEYKFVVDEDFSADILAQLEFNSCPNIFLSPENVRSEMIKKALSIVAQYPFCRLTLQLHKLIGV. 202
265 3.000e-43UniRef50_A0A150J9N3 7-carboxy-7-deazaguanine synthase n=6 Tax=Euryarchaeota TaxID=28890 RepID=A0A150J9N3_9EURY  ali  26  3...............TLLVSEIFFSFNGEGLEIGKPTVFVRLSGCNLNCSWCDTKYA---------------NYNAKEMNTEEIMREIKKQSKFNKS---VLITGGEPLNQDIHKLVNELSKERYHIGIETNGSIDILLKIDFISADIKSPSSLTFNKIVNA-ILKKQGQMKAVISDKKDYEFVKLIIQPCWGELSYKELCELYISNHDNVRLMLQIHKI.... 211
266 3.000e-43UniRef50_R7IHN4 7-carboxy-7-deazaguanine synthase n=1 Tax=Sutterella sp. CAG:351 TaxID=1262975 RepID=R7IHN4_9BURK  ali  29  2............EEIRYSINEIFASVQGEGLLAGTPAVFVRLQGCPVHCPWCDTKYSWKEDGSGTIPLSEVLVKDSRPRSADASLDELVNLIERWPRIPLVVITGGEPAEQPIRPLTERLIAAGKRVSLETSGFLEIDVAPEFVTVSPKITVPGALERADEVKMVIGDESDLAALDAITDKIPASTPISLQPLSMEDSALCRTAVERGGRYRVSVQLHKVL... 223
267 3.000e-43UniRef50_A0A062TP14 7-carboxy-7-deazaguanine synthase n=12 Tax=Hyphomonadaceae TaxID=69657 RepID=A0A062TP14_9RHOB  ali  24  1..............MRLAVTEIFHSLQGEGVSAGKPSVFVRLSQCNLHCVWCDTAYTWNFQGDDTPGAPRKYDRAQETVSVEELTEHLLAL-----PCRRIIFTGGEPLLQQLGELIQRLKEADFYIEIETNGTISPVGLAADLIDQFNVSPKLAHSGNDTAIRHKLETLRFYANDPRANFKIVVESPPDL---EEVKSLVVETEMPLSRVWLMP......... 210
268 3.000e-43UniRef50_A6DHQ9 7-carboxy-7-deazaguanine synthase n=1 Tax=Lentisphaera araneosa HTCC2155 TaxID=313628 RepID=A6DHQ9_9BACT  ali  22  2................LYITEIYKSLQGESTWSGLACIFIRLSGCNLRCSWCDTEYS---------------FTSGDKLSIDNILDRVEQL-----NCDLVEVTGGEPLAQDKVELVQKLLDLGKTVLVETGGHMDIVSKESIRIMDIKCPASKMSHKNDNIAKLTPKDEVKFVIQNKEDFLWAEKTIREYKLEKKCTELAGLILQSGLNIRMQIQLHKLIW.. 205
269 3.000e-43UniRef50_A0A2N6FET8 7-carboxy-7-deazaguanine synthase n=2 Tax=Desulfuromonas sp. TaxID=892 RepID=A0A2N6FET8_9DELT  ali  20  1......MPVPATAKDSAPLVEIFSSAQGEGPLVGCRQIFVRFCGCNLECAYCDTAHYRDNSCRVQSEPGSHVFEEWNPVRLEQVIHLIESWLAEYPGLHHLSLTGGEPLHHGNILVRWLPPVRELPIYLETNGTQPLIDEIDYISMDIKLSSVCGFATPWGRHRETKTICVKLVVDANTPVEIVTLVLQPLTSAERLLELQAAALTSYPDVRIIPQTHRFL... 250
270 3.000e-43UniRef50_A0A0F9SLS6 Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=A0A0F9SLS6_9ZZZZ  ali  43  1..............MSYRVREIFSTLQGEGSRAGSLSVFVRFAGCNLWNGRPEDREGACALWCDTDFV------KGKEVSAEDVRLELDRLWERLPSAKWCVLSGGEPLLQVDHALVDELQRHGWNVAIETNGTLDALDLMDHVCVSPKLGSTIERMRADELKVVLPVDFEKRLVDLQESGEWLYIQPQDYTDEERNLNRCLNFVANHPEWRLSLQVHKYARIP 239
271 4.000e-43UniRef50_A0A1M5PD70 7-carboxy-7-deazaguanine synthase n=1 Tax=Thermosyntropha lipolytica DSM 11003 TaxID=1123382 RepID=A0A1M5PD70_9FIRM  ali  22  1..............MKAYLIEIMESIQGEGLTAGMRQIFLRFGGCNLRCSYCDTGASLATPEEGFFYPQAGNSRSKETLSVIELV--------RRFSSSWISFTGGEPLLWSDFELGLKLKPAGYRFLLETNGTLKCLPLVDLISMDFKLPSATGKDNWDNHYFFLREAVVKIVANGKIDRKIPVYLQPDLKLLPFLLRMQEKGLNRLEDVRIMPQLHVFLGL. 242
272 4.000e-43UniRef50_B1I3W0 7-carboxy-7-deazaguanine synthase n=1 Tax=Desulforudis audaxviator (strain MP104C) TaxID=477974 RepID=B1I3W0_DESAP  ali  22  3..............ITAPVTEVFTSVQGEGPYLGCRHMFVRFAGCNLQCAYCDTP-APAGRRCRVENTPGRRVFTWYPNPV--TVQMLLDWTSRAPHFHALALTGGEPLLHADFLFLVGFREYGGRCYLETNGTLPLARLVDIVAMDVKLPPEAEHRRFLEA-IGPAHAFVKVVVGSETDAELVLQPVTPVSGPERLLEMQERCLARLPDVRVIPQVHRTLGV. 245
273 5.000e-43UniRef50_Q02CA2 7-carboxy-7-deazaguanine synthase n=17 Tax=Bacteria TaxID=2 RepID=Q02CA2_SOLUE  ali  23  1................MKIAELFYSIQGEGALLGVPSVFIRTSGCNLRCSWCDTPYTSWRP-------------EGTDLTLEQILDEVGA-----HPARHVVVTGGEPMIAPDIALTQRLRARNLHITIETAGTVFEPVACDLMSISPKLPDDARFSRQHERLRIQTPVQLKFVISQPGDLEERVILMPEGVDPARLRERALWLAEICKGFRFSPRLHVDLW.. 218
274 5.000e-43UniRef50_A0A1M6VWD0 7-carboxy-7-deazaguanine synthase n=9 Tax=Bacteria TaxID=2 RepID=A0A1M6VWD0_9BACT  ali  44  2..............PTYRVKAIWKTLQGEGFFAGRPAVFVRFVGCNLWSGQERDREADCPRWCDTDF----RKAGSRPYTADEL---VAALQEVGGPIRFCVLTGGEPLLQLDASLMHALQAAGYFVAIETNGTVSLRQACDWIVCSPKLPDRLALEYFDELKLIRPEQYARFVGGRRIPLLW--LQPEDGPRLAEAQRCAVELALAHPEWRVSVQIHKVLGV. 232
275 5.000e-43UniRef50_A0A2N2D201 7-carboxy-7-deazaguanine synthase n=1 Tax=Firmicutes bacterium HGW-Firmicutes-15 TaxID=2013776 RepID=A0A2N2D201_9FIRM  ali  22  1..............MKANLAEIMESIQGEGLLVGSRQVFLRFTGCNLRCAYCDTPGSFEPLPYCQVAKVTGREQVPNPFSVEQIREHLKNYSS-----QWISLTGGEPLLWADFIMGEKLKPQGYKLMLETNGTLECLPYIDLISMDYKLPSATGVNCGAEHAQFNKAVYIKIVIDSKVEREIITAVNPNILSIEKLLDLQKMCQEKIADVRIIPQIHKMMGL. 242
276 5.000e-43UniRef50_A0A1F3MG28 7-carboxy-7-deazaguanine synthase n=3 Tax=unclassified Bacteroidetes (miscellaneous) TaxID=37452 RepID=A0A1F3MG28_9BACT  ali  29  12................LPILEEFYTLQGEGYHTGTAAFFIRIGGCDIGCNWCDSKSSWS-------------FGTHPMIDVDDLVERVSAY-----PAKAVVVTGGEPGLFPLDYLCRQLHSRQIKTFLETSGAYDLSGEWDWICLSPKFQSP------PVPDNYLRANELKVIIEKESDFRWALYLQPEWSQRRTLLEPIISYIESNPRWRLSLQTQKYIGIP 207
277 6.000e-43UniRef50_O54060 7-carboxy-7-deazaguanine synthase n=37 Tax=root TaxID=1 RepID=O54060_RHIML  ali  23  9................IRVSEIFPTIQGEGVLIGLPTVFVRSGGCDYRCSWCDSLHAVDSNYRHEWQT----------MSTEEVWQEIVRLS--GGEAVMVSLSGGNPAIQPLGDLIGRGHENGYRFALETQGSVDWFANLDVLVLSPKPPSSGMETDWEALDDNKPQTVLKFVVFDEADYAYAMTLQPGNHDIDGVMERMRWLVDRADRWRVLPQLHVLIW.. 239
278 6.000e-43UniRef50_A0A2M7SF68 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Desantisbacteria bacterium CG_4_10_14_0_8_um_filter_48_22 TaxID=1974543 RepI  ali  26  3...............SAWVAEIFDSIQGEGIYAGVRQIFIRFSGCNLRCDYCDSRLSWKRRPRPIVLIGRERLKLKNPISSKDIVAVLKEYLTFNFSAPYISLTGGEPLLQADFELIPDLKGLGFRIYLETNGTLPIIKNVDFVAMDIKFPSATGRRDLWEKHRRFLRAFVKVVVTAGVDRKILVIQPASGQRHKDLFEFQRIAGHSLEDVRIIPQFHKILGI. 284
279 6.000e-43UniRef50_A0A1I6D587 7-carboxy-7-deazaguanine synthase n=4 Tax=Desulfotomaculum TaxID=1562 RepID=A0A1I6D587_9FIRM  ali  22  3...............RLPVCEIFPTIQGEGLYSGHRTMFIRMAGCDYRCSWCDTQYAQSVS------------QAQQLLSEEEIVHLVNKRSC--GGSRRVTVTGGNPCIHDLDKLIGLLHQENYVIHIETQGSIPWLYNADHVCLSPKPPSSGPVSAFDKFMHSDTSKELKLVVGTEEDYIYAKQIYKQYPSKEDPLPVLKWLIEYGDNVKVLPQLHVLIGI. 218
280 7.000e-43UniRef50_Q8TX58 7-carboxy-7-deazaguanine synthase n=2 Tax=Methanopyrus TaxID=2319 RepID=QUEE_METKA  ali  25  1MGTGGRGRPTPG----LNVYEVFLSLQGEGKFVGEPQAFVRFSGCNLRCAYCDEPASRSSRRRALIRRVSGEVELELPVPPEDVVEVLVELEDLEDTFGTVSLTGGEPLVQPLKELIERLRERGFRVLLETNASLPIDELADVVSADVKLPSHGPNMDLRFLERISAEVYAKVVLVDEECYEPIYLQPATEHDLEDLWELAGLV---NADVRVLPQVHKL.... 246
281 7.000e-43UniRef50_S0EVQ6 7-carboxy-7-deazaguanine synthase n=3 Tax=Chthonomonas TaxID=1077265 RepID=S0EVQ6_CHTCT  ali  22  9...STTRPEAEARLPKARLVEVFSSVQGEGLLVGYRQVFVRTYGCNLRCTYCDSPETLKESPMPTVCRIEWPVGTGRPVEVEQLTQVLQRFLKM--PHHSVAITGGEPLLQARFLWLPAVRSLRLKTFLETNGLLPIVALLDYVSMDIKAPSATMHRQFLEVARDELDRAIDLIESVDASIPFILQPVTPFVSPARLLELQSRAAARLSEVRVIPQTHKL.... 267
282 8.000e-43UniRef50_A0A0B5RU85 7-carboxy-7-deazaguanine synthase n=34 Tax=Bacteria TaxID=2 RepID=A0A0B5RU85_9FLAO  ali  29  16................LPLMEEFYTIQGEGFYSGHAAYFIRLGGCDVGCHWCDVKESWDAELHP-------------LTDVQQIVSRASEEAN------LAVITGGEPLMYNLDVITAELKKAGLQTNIETSGAYELTGDFDWICLSPK------KNKLPTQSVYDAANELKVVIYNKHDFIFALLLQVEWSKRAEMNPLIVEYVKKNPKWKISVQTHKYLDIP 210
283 9.000e-43UniRef50_A0A2H6ALR2 7-carboxy-7-deazaguanine synthase n=9 Tax=cellular organisms TaxID=131567 RepID=A0A2H6ALR2_9BACT  ali  21  1................MKVSEIFFSIQGEGVEIGLPTVFLRLFACDLRCSWCDSMYAVEGR-------------DFKEMTLSDVKRELERF-----GCKRVCITGGEPLIQKLEVLVRDLLGEGYSIVLETGGHKEPPPVFCIISMDCKCPSSGMEKKMDLFERLRPKDQLKFVIKDEVDYAYAKEVLNRYSIKANIVWLAEKVINDRLGVRVLPQLHKVIW.. 207
284 9.000e-43UniRef50_A0A172TVM6 7-carboxy-7-deazaguanine synthase n=6 Tax=Bacteria TaxID=2 RepID=A0A172TVM6_9BACT  ali  41  1........MNQHQESKYRVKAIWKTLQGEGLFAGRPAVFVRLVGCNMWSGYEQTRQRDAERNGGSCPLWCDTDFTKEGSQDYTAEALAAAMQKVGGDVRFCVITGGEPLMQLDYTLVKALHKAGYFIAIETNGTLSLLEAPDWIVCSPKLAVPLQLEFFDELKLVKPEDFDAFVGLQRINKIHNHTLPLLWLQPEEARKMAIETALAHPQWRVSVQTHKILNV. 237
285 1.000e-42UniRef50_B2KC63 7-carboxy-7-deazaguanine synthase n=2 Tax=Elusimicrobium TaxID=423604 RepID=B2KC63_ELUMP  ali  27  2............QAPSFKLTEIFYSLQGEGMYTGTAAVFVRLSGCLMGCSFCDTD-----------------FKENFVMTSEEIIKEVKKY-----PSKIVIITGGEPAEQDICALIKSLKQAGLKVHIETNGSIFDAQGVDNLTVSPKT--------YVDPNMLKSAHVIKIVVGQDTDIEGRLIYLQPESNKQENIDLCVKLIKENPFLRLSLQTHKFAKIP 195
286 1.000e-42UniRef50_C1DRF0 7-carboxy-7-deazaguanine synthase n=12 Tax=root TaxID=1 RepID=C1DRF0_AZOVD  ali  20  1..................................MPTVFVRLTGCPLRCGYCDTAYA---------------FSGGAVLPLSVILERVASYGPR-----YVCVTGGEPLAQPNIELLRLLCDAGYEVSLETSGAFDISAVDCRVSLDLKTPDSGARNRYANMTLLTRNDQMKFVLCSRQDYEWAVSKLIEYRLDERVRELADWIVADNLPVRLQLQLHKILW.. 187
287 1.000e-42UniRef50_A0A2N0KVF3 7-carboxy-7-deazaguanine synthase n=9 Tax=root TaxID=1 RepID=A0A2N0KVF3_9CHLR  ali  27  19....................EIFHSLQGEGHSVGTPTVFLRLALCNLTCSWCDTKYTWDW-------ANFDPKKEILSLSLEAIEERILSY-----DCPHLVITGGEPMMQQDAPLALSLKDKGFYIEVETNGTLAPNAEMNSAVSQWNVSPKLANSGVASDRREVPDALTAFAEIETAYFKFVMAQPQDVN---EVLTLVDRYAIPPQQVILMPQ........ 201
288 1.000e-42UniRef50_C3JCW4 7-carboxy-7-deazaguanine synthase n=8 Tax=Porphyromonadaceae TaxID=171551 RepID=C3JCW4_POREA  ali  29  6......PPIAMLDHLELPVNEIFYSLQGEGAQVGLPMVFIRLSSCNLRCSYCDTDFS-----------------SFTPMSLEAIVAELASF-----PTHNILWTGGEPTLHLTEEVVGFFHQKGYRQSIETNGTRPVPRGIDYITCSAK--PESFPHLWENFPHGV--DEWRFPFGASAPLPPRTYCLSPIYEPGEALEECIEYIKQHPTWRLSIQLHKIIGI. 211
289 1.000e-42UniRef50_D3DIS0 7-carboxy-7-deazaguanine synthase n=3 Tax=Bacteria TaxID=2 RepID=D3DIS0_HYDTT  ali  22  12................LSINEIYPSVQGEGLLIGKPCLFVRFQGCNLRCPWCDEPSALSFKRANTDLK--------------ELLQELQKY-----PQKHVVLTGGEPFAEPNLHLLQELLCRGYSVQIETNGTLWNENLREVVSVHITCSPKGVADWYVHPAVLSSAKELKFVVDHELCYEFMVVLQPEGNKTKKALELQNLLLREGYTVRVVPQMHKLIGL. 217
290 2.000e-42UniRef50_R7H9B4 7-carboxy-7-deazaguanine synthase n=19 Tax=Bacteria TaxID=2 RepID=R7H9B4_9FIRM  ali  26  1........MNMNNQIKYPVVEQFVSINGEGTKAGELAVFIRFKGCNLNCSYCDTQWA------------NRQDTPAVEKTAAELVADVCR-----TGIDNVTMTGGEPLLQIELALIKELLSAGKAVEIETNGSVSXXXXXXXXTMDYKLAGSGMETFMQNFSELQPQDTVKFVAGSIEDLEKTRQIIQEYGLTQKCPADIVEYMKAHNGVRMQLQMHKFIWAP 231
291 2.000e-42UniRef50_E1QUY3 7-carboxy-7-deazaguanine synthase n=5 Tax=Thermoproteaceae TaxID=2267 RepID=E1QUY3_VULDI  ali  26  1..............MKVRVIEIFKSWQGEGPNAGREAVFLRLALCNLRCSWCDTKYSW---------------FGGTEMNVHDVYEVLMK---TAGGVRHLVVTGGEPLLWSLLQLLRFIRAQGFFVEVETNGTLRPGELVNYV-DEFNVSPKLSNSGVSVRVRVNELAIRDFVMSGKAIFKFV---VDKPGDVDEVLWFINKFGIPRDRVYLMSQ........ 183
292 2.000e-42UniRef50_D3V503 7-carboxy-7-deazaguanine synthase n=17 Tax=Enterobacterales TaxID=91347 RepID=D3V503_XENBS  ali  31  1..............MIYPINEIFQTLQGEGVFTGVPSVFIRLQGCPVGCSWCDTKHTWEKEADKQQENILVKSQDSDTWGAATARQIINLFIRQGYTARHIVVTGGEPCLYNLRPLTETLESEGYQCQIETSGTHAIQSEKTWVTVSPKVKLPEAMNRANEIKHIEALDELLTMLDEKAD---PVIALQPISQKEEATRLCIETCIAR-NWRFSMQTHKYLNI. 222
293 2.000e-42UniRef50_A0A1V6HRE4 7-carboxy-7-deazaguanine synthase n=1 Tax=Bacteroidetes bacterium ADurb.Bin035 TaxID=1852799 RepID=A0A1V6HRE4_9BACT  ali  27  13................LPVLETFYSLQGEGLHTGLASFFIRLGGCDLSCWFCDSKETWNPDIN-------------NLTTPFELLEKAMIY-----DTKHIVLTGGEPILYPLDQLINLFHAHDYYIHLETAATAQWINNIDWICVSPKNHS------YINDEWLKNANELKVIISDLEDLECYLFLQPEWSKSKKILPEIIKYIFNNSKWRLSIQTHKYLNL. 207
294 2.000e-42UniRef50_A0A2M6Z2D6 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Candidatus Hydrogenedentes TaxID=1046981 RepID=A0A2M6Z2D6_9BACT  ali  23  1................MIIKEIYRTLQGETTRIGEPCVIVRLTACNLHCSYCDTEYAM---------------EGGKEMSVEEVLQRIAEL-----DTKLTVITGGEPLLQADSSLISELLDKGHDIQVETNGAKDIIDKRASVIMDLKCPSSGESEKLSNIQKLKSGDEVKFVIGTKEDYEWAKNIMRSEKFPEGCKELADLILSDKLDVRFIPQLQKIIW.. 217
295 3.000e-42UniRef50_A0A0B0Q3X7 7-carboxy-7-deazaguanine synthase n=3 Tax=Sulfurospirillum TaxID=57665 RepID=A0A0B0Q3X7_9PROT  ali  29  2................LNVVEIFYSIQGEGAQVGVPCVFIRLHGCNLACSFCD---------------EELHKGAYERLTFEAVLERIAAY-----PSKNVIITGGEPSLYDLRDFIAVLHSHMYRVGVETNGYNFAIADADWITYSPKDWDAIALSGYDEIKFVVDKDVEKIAAFQSDKAMFIQPQNKPHAPDMSNVRFCLEFVMQHPQFTFSAQLHKFLGV. 191
296 3.000e-42UniRef50_A0A2V9MVN2 7-carboxy-7-deazaguanine synthase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9MVN2_9BACT  ali  28  1................MQITEIYKSLQGESTYAGMPCVFVRLTGCNLRCTWCDTEYS---------------FYGGKKMTPEQVFDEAQHLSA---ALGLIEITGGEPMLQELVPLMQRLVDSGYKVLLETSGERPLDRVPVIKVVDVKCPDSGEGDHIENLETLQPHDEIKFVISGRSDYEFA........................................ 156
297 3.000e-42UniRef50_UPI000BB77974 radical SAM protein n=1 Tax=Bacillus sp. FJAT-45350 TaxID=2011014 RepID=UPI000BB77974  ali  21  20...............KLPMVEIFETVEGEGSGAGFPTVFVRVFHCNLRCTWCDTPYSYAPS------------KPEFEATIQEIVDKISEFSSKR-----ICFTGGEPLIHGKKSAALLLAMAELPIHIETNGAIDLLPFVVRFVIDYKLPASGENEKMDNFSLLAQSDEIKFVIASDEDFEIAKETIQTYHDLGQILTLVEKVLEKLSNVKVSLQLHKIIWDP 241
298 3.000e-42UniRef50_A0A2E4RF38 7-carboxy-7-deazaguanine synthase n=1 Tax=Flavobacteriales bacterium TaxID=2021391 RepID=A0A2E4RF38_9FLAO  ali  25  2................IPIKETFLSFQGEGYFAGQASYFIRTQGCDIGCHWCDEPASW-------------EFKSGINQSLSNILKDIKK-----SNVKNVIVTGGEPLIHDLSNLTNEISKNNFSLHLETSGSYALTGNWNWITLSPKPPLKSIYSHTSE---------LKVVIYNNKDFEWALEQQPEWSRKEIMQQQILDFISKNPRWKLSLQMHKYLNV. 199
299 3.000e-42UniRef50_A0A2P6C057 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A2P6C057_9BACT  ali  39  1.......MPRPFSAPSYRVKHVFQTVQGEGFWVGRPALFVRLVSCNMWSGYEADRADRTGADCPRWCDTDFTKEGASTLTADQLTDQMREI--GGPAIDFCVLTGGEPLLQADAALVHALHEAGYEVALETNGTVPLLHTPDWVTCSPKRPDQLALERYDELKLIVPDNYAQFAEHNGRERRLLWLQPEDGPRLEEAQAMAVDLALKHPEWRVSTQTHKVLNV. 239
300 3.000e-42UniRef50_A0A1Q9NBC4 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Heimdallarchaeota archaeon LC_3 TaxID=1841598 RepID=A0A1Q9NBC4_9ARCH  ali  24  1................MEIVEIFQSLQGEGSLIGVPMVFIRLWGCNMKCIWCDTKYSWSPEF--------KYLTKRALFTPEQLVQE---LKNKYKSKTWINFTGGEPTLWKDEILTIELLNRFFFTCIQTNGKIWDEKLLDKICMDIKCPKSGEESNLAYLKKLRKKDEVKFVLDNEDDLNYAINVINDYESFDEYFKKIKWIIEQTKNIRILPQYHQLLW.. 219
301 3.000e-42UniRef50_G2DIR3 7-carboxy-7-deazaguanine synthase n=16 Tax=Neisseriaceae TaxID=481 RepID=G2DIR3_9NEIS  ali  27  1......MTEIRPENPQYRIVEIFESLQGEGYNTGMPAVFIRLGKCNLACSWCDTDYL-----------------TFNMMSLQDILGRLKSYTARN-----IIITGGEPTIQPLDILLDTLKAEGYTLCIETNGLNPAPPQIDFVTASPKACYAEKYEKADEVRIVADGDVLAFCMEHKIRAKHYYLSPCEQNGEMNIYDTIRQIGLLNSRWQLSVQTHKWAGI. 209
302 3.000e-42UniRef50_A0A1V5MR56 7-carboxy-7-deazaguanine synthase n=1 Tax=Planctomycetes bacterium ADurb.Bin412 TaxID=1852905 RepID=A0A1V5MR56_9BACT  ali  23  1..............MTLRISEIFYSLQGEGRLAGVPSVFIRLAGCDLRCLWCDTPYALRAEQ-------------GQALSLEQIMDQISAF-----DCSHIVVTGGEPLLAPELPLLQELKNRNKHITLETSATQYRPVIADLVSISPKLAHSIPHTGIHKTRRLNLEAIQHFMDHHDYQFKFVV-------GSRADLEEVDQILAKLRNVRIMLQQHR..... 198
303 4.000e-42UniRef50_C9RPI8 Pyruvate formate-lyase-activating enzyme n=22 Tax=Bacteria TaxID=2 RepID=C9RPI8_FIBSS  ali  17  1..............MTLRINETFGSVDGPGIR-----FVVFTQGCPMRCKFCHNPETWDFGT----KSANGTANGSFEISAEDLLKKALRYKPYWGTDGGITVSGGEPLAQIDFEFFEAAKSAGVHTCVDTCGFRPLMKSTDLLLVDIKHIDADAHKELTGHGNENIIEFFRYLDRIQKPIWIRHVLVPGISDNDEALTRTRDFIRTLHNVRVVLPYH...... 214
304 4.000e-42UniRef50_A0A0T5ZYY1 7-carboxy-7-deazaguanine synthase n=9 Tax=Candidatus Rokubacteria TaxID=1752708 RepID=A0A0T5ZYY1_9BACT  ali  23  3......QRADLRKSLTGRIAEVFFSIQGEGPTAGMPAVFVRLQGCSVGCAWCDTKYSWDPR-------------AGREVALDEVVEEAAAFPCRRS-----VITGGEPLESSLFPLVEALTTRGFTLEVETSGTLAPPAV---AVAQWNVSVKLAGSGVPEAKRINPDAIREFLR-LGAWWKFVVV---DASNVAEVLRLAERFAIPRERIRFSPRLHILLW.. 222
305 5.000e-42UniRef50_B2RKC1 7-carboxy-7-deazaguanine synthase n=40 Tax=Bacteroidia TaxID=200643 RepID=B2RKC1_PORG3  ali  30  1................MLINEIFHSLQGEGANTGRAAVFVRLAGCNLACPYCDTDFAQ-----------------GKKMSLEEIARSIEHYPTRF-----LIWTGGEPTLQLTEEATAYFHRLGYYQAIETNGTRLVPKGIDYISCSPKAIGKLKENFPDGVG------EFRFPLGSDTPLPPPIDLVSPIFAGDDAMERCVEFVKAFPAWCLSIQMHKLIHIP 197
306 5.000e-42UniRef50_D7CMQ0 7-carboxy-7-deazaguanine synthase n=1 Tax=Syntrophothermus lipocalidus (strain DSM 12680 / TGB-C1) TaxID=643648 RepID=D7CMQ0_SYNLT :_  ali  24  1..............MKAYLSEITESIQGEGTLAGSRQIFLRFCGCNLRCPYCDTVGSLSKTPSCKIFLKPGSKNDFREYNPLSISDVVKATANF--DTRWVSLTGGEPLLWADYLLAPILVSKGYRMLLETNGTLDILEFTAVISMDFKLPSAIGIDLFPVHKR-----FLELAACRPVYVKVVVTPSTEPWEIEKLFDLQLDALKHLEDVRVIPQIHKYL... 240
307 5.000e-42UniRef50_A0A2D6WS89 7-carboxy-7-deazaguanine synthase n=107 Tax=cellular organisms TaxID=131567 RepID=A0A2D6WS89_9BACT  ali  32  26...............SYNIVEIFHSVQGEGYRSGIPHVFIRFGVCNLRCEWCDT-----------------NFDVYEQKSVAEIMEVV-----GQFPCKNIIFTGGEPMLNDLWPLARVLKKDGYHLSVESNGTVAIPGLLDWICISPKPNVSIKQRAGDELKCVYVGQPLSMYDGLKEGFSHHFLQPCEEASVEENFALTEAVVKENPQWRLSLQTHKWMGI. 221
308 5.000e-42UniRef50_A0A2E6D665 7-carboxy-7-deazaguanine synthase n=3 Tax=cellular organisms TaxID=131567 RepID=A0A2E6D665_9BACT  ali  21  1.......MASTSTSTRAPIMEVFASIQGEGAYAGEAQVFLRLAGCPLRCDWCDTPHSWDDERPARVVTPEGPKRHTAWANPFQVATWVAACEPRE--ARTVSVTGGEPLMWPEFLLGLPDMLAGRRLHLETAGAHPVAPAFDHLSLDLKLPNPHTSEDWTRVRREVHHACAKIVVRSGRDVPLYLTPVSPMPEPKFLEELVEEARDLHLDVRVMPQLHRVLSIP 268
309 5.000e-42UniRef50_A0A0J1F735 7-carboxy-7-deazaguanine synthase n=1 Tax=Peptococcaceae bacterium CEB3 TaxID=999898 RepID=A0A0J1F735_9FIRM  ali  26  7...............QYPVNEIFESIQGEGIWSGIPAAFVRLEGCNLRCRWCDTKEAWSG-------------GNASRLTAAEILTAVNFE--------LVIVTGGEPLLHDLTELFLTLQQAGKKVHVETNGTQPWRPPDIWLTVSPKVQPSLAARAGEYKEAFRPEIIREFYTQLGHRQKEPLIFLSPENVRPEMVEKALQIVFQYPFCRLMLQMHKLIGI. 206
310 6.000e-42UniRef50_A0A2E3XMP8 7-carboxy-7-deazaguanine synthase n=54 Tax=cellular organisms TaxID=131567 RepID=A0A2E3XMP8_9BACT  ali  30  14................FPIVEIFHSVQGEGYHAGXPSIFVRFGGCNLRCXWCDTDFDIWTD-----------------MSISQIVNELSKY-----DCDRIIFTGGEPALQDLVTLSGFLKPLGYYLXIETNGTIAIPDTIDWICVSPK------DQEYNNIKRQRVGDELK-VVYLGQDLEFSHLFLQPLYDEGQSTEWTFEKVRSNPEWRLSLQTHKWMGV. 208
311 6.000e-42UniRef50_T3DG99 Pyruvate formate-lyase-activating enzyme n=51 Tax=Firmicutes TaxID=1239 RepID=T3DG99_CLODI  ali  17  2..............IKGKIHETFGTVDGPGIR-----YILFFQGCPLRCKYCHNRDTWDT-------------KSGKEYTVDEIITDALKYTSFMKFGGGITASGGESTLQPEFELFKKAKENDIHTCLDTSGFVPILDNTDLVLLDLKHMVEEKSINLTGVGMDKALKLARHLDSRNIPVWIRHVLVPGITDDTDNLEKLGQFVSTLKNVRFSMGIHKWLGI. 212
312 7.000e-42UniRef50_A0A1H5P660 7-carboxy-7-deazaguanine synthase n=5 Tax=Actinobacteria TaxID=201174 RepID=A0A1H5P660_9ACTN  ali  23  2.............EPELVVNEIFPTVQGEGRSLGRRCAFLRLGGCNLSCTWCDTPYTWDWTGAGDSGVAYDPHQELHRRPVREVAEELLAF-----GVELIVISGGEPLGQQLVPLVELLTARGLEIEIETNGTHAADPALVAAGVRFNVSPKLAHSGDAAHRRIVPAALKSLAATDGTTFKFVC---RDTRDLDEVAALVSEF--GLDPVWIMP......... 196
313 7.000e-42UniRef50_A0A0Q1FYG6 7-carboxy-7-deazaguanine synthase n=1 Tax=Desulfuromonas sp. SDB TaxID=1735325 RepID=A0A0Q1FYG6_9DELT  ali  22  2................FKINEIYPTILGESLYTGYPFIIVRFTGCPLRCSWCDTQYAY---------------YEGNDYSLAGVMDEIAKFKYFN-----VLLTGGEPLAQNNLELIDQLLHKKYQIVVETSGALPVSGLAEKVVMDYKLPSSGMENKMQNLNYLKTSDEIKFPVADKKDFDKVKIAVSPVMGKIDFSALAELILSSKMNIRLNLQIHKIIW.. 206
314 7.000e-42UniRef50_UPI0009DDBA6F radical SAM protein n=1 Tax=Lachnospiraceae bacterium C6A11 TaxID=1410622 RepID=UPI0009DDBA6F  ali  23  13............DKLRFAVAEKFISINGEARRAGELSVFIRFRGCNLRCNYCDTLWACDEVKQEENCTNTGAECGTEYMTAEEIYGYIK-----SSGVKNVTLTGGEPMIQKNELLELLSEDKNLRTEIETNGYYEKMPDNISFTVDYKCPGSGMEKAMHNFEKIRSCDTVKFVVSDRADLEKMCEVISEYGLTEKCTREIVDYMIENKDVRLQLQIHKYVWDP 277
315 8.000e-42UniRef50_F8IES3 7-carboxy-7-deazaguanine synthase n=51 Tax=Bacteria TaxID=2 RepID=F8IES3_ALIAT  ali  19  29.............QLSLPMVEIFETVEGEGTRAGFPTTFVRVFHCNLRCTWCDTPYSYAPERPAFH------------ATLREIAKQVEAF-----GWPNVCLTGGEPLIHQLLIEAIADIEWVRDVHIETNGAIDVRPYVVRFIVDYKLPASGEDSRMIGEHLLSERDEVKFVIADERDFEFATILMSPVWDTMPPRDLVALILKHRLDVKLNLQLHKVIWDP 252
316 9.000e-42UniRef50_A0A0M2JTH2 7-carboxy-7-deazaguanine synthase n=5 Tax=Actinobacteria TaxID=201174 RepID=A0A0M2JTH2_9MYCO  ali  25  1..............MTLYVSEVFPTVQGEGPYMGRRAMFVRLGGCNLSCSWCDTPYTWNGARFDLRHEIAPQSSESVLVQLDEWAD------------GIVVITGGEPLLQPEFILLRALRNRGREVHVESNGTIEVLEMLDVVVLSPKLANAGKHRGGQSAAMHAGWATV--VAEREVYLKIVC---RNGADVASVAELAEDIGWPRDRVWVMP......... 193
317 9.000e-42UniRef50_A1APX7 7-carboxy-7-deazaguanine synthase n=1 Tax=Pelobacter propionicus (strain DSM 2379 / NBRC 103807 / OttBd1) TaxID=338966 RepID=A1APX7_P  ali  20  4...............SLPIAEIFSSIQGEGYLAGRRQIFIRLTRCNLECSYCDTGFGEGESCLVENSPGSNVFHFPRAVGLDRLMDILNAWWALPRAHHSISLTGGEPLLFAPLLSDWLPRLRGIPVHLETNGTLPIIRLVDYVSMDMKLPSTAA---CGGELWDTHRRFLETARGKNVSVKIVVGEQSDAAEIEQVCRIIAQIRPDTPDVRVIPQMHKLMGV. 248
318 9.000e-42UniRef50_A0A271LQ49 7-carboxy-7-deazaguanine synthase n=1 Tax=Mesorhizobium temperatum TaxID=241416 RepID=A0A271LQ49_9RHIZ  ali  60  1..............MSYAVKEMFYSLQGEGRHTGRPAVFCRFAGCNLWSGRERDRAKAPCNFCDTDFVGVNGIGGGRFNDASSLAIAIENMWGGGASERFVVLTGGEPLLQVGDAILSEFHDLRFEIALETNGTLAAPNTIDWITVSPKGATTLVQTAGNELKLVFPQA....................................................... 155
319 1.000e-41UniRef50_A0A0J8GRP2 7-carboxy-7-deazaguanine synthase n=126 Tax=Bacteria TaxID=2 RepID=A0A0J8GRP2_9ALTE  ali  27  1..............MNYPVNEIFETIQGEGCYTGVPAIFIRLQACPVGCAWCDTKHTWEKSESTQVKQSSNESDCWADFTENDILNLLAKYTA-----KHVVITGGEPCIYDLIPLTELLNNAGYSTQIETSGTFEIKTHANYVTVSPKVNMKGGYERANEIKHQQHIDDLDELLAKIDDLTDKTVCLQPISQKKRATELVIQTCIKR-NWRLSAQMHKYLFI. 220
320 1.000e-41UniRef50_Q8K9D9 7-carboxy-7-deazaguanine synthase n=195 Tax=cellular organisms TaxID=131567 RepID=QUEE_BUCAP  ali  23  1..............MYYPINEIFQTIQGEGYYTGTPSIFIRLQGCPVHCKWCDTKYTWKCNNEDSYEKIIMKKKSNRKWSYMNVKEIILIIKIKKWTAKHIVITGGEPCLYNLLEITKELEKEDYKCQIETSGTELIKSLNTWITLSPKISNEIKYPVLKKEDLFYLNSILKKIKNKKHNLIF----LQPISQNEEALNICIKTCI-IKNWRLSVQIHKYLKI. 218
321 1.000e-41UniRef50_B0G5G8 Pyruvate formate-lyase-activating enzyme n=17 Tax=Bacteria TaxID=2 RepID=B0G5G8_9FIRM  ali  15  1..............MEGYIHESFGSVDGPGVR-----FVIFTAGCPMRCQFCHNPDTWNM-------------KTGTLTSTDDLIKKALRYRSYWGNEGGITVSGGEPLLQIDFELFKKAKENGIHTTLDTSGFNELMQYTDLILLDIKHIDEKEHIRLTGHTNKNILDLATYLSDMKKPVWIRHVLVPKRSDKDEYLDRLHEFILTLHNVRVVLPYH...... 204
322 1.000e-41UniRef50_A0A1W9RP92 Anaerobic ribonucleoside-triphosphate reductase activating protein n=9 Tax=Bacteria TaxID=2 RepID=A0A1W9RP92_9BACT  ali  17  1..............MKIAGFQKFSLID----YPSKISAIIFTQGCNFRCPYCHNPELVNPELFSD--------------TLDEDL-ILTFLSKRIGKLDGVVITGGEPLLQHDLIFIKKVKEMGYLVKLDTNGSYPAKNLIDYIAMDIKAPLEKYHNVVQADVCEKIMESITIILNSNIDYEFRTTVVKDL-LIEDDLICIAKLIRGAKRYVLQ.......... 189
323 2.000e-41UniRef50_E1L5B1 7-carboxy-7-deazaguanine synthase n=11 Tax=Veillonella TaxID=29465 RepID=E1L5B1_9FIRM  ali  20  3..............LSMNVIELFSSIDGEGKRQGFLTTFLRLHDCNIRCSYCDTLYSYGPESTF------------ESMSVQAVADVIEQLENHR-----ITVTGGEPLLQEELIDELTRRNARYDFNIETNGTIIPSFHRDWFTYDYKTPSSLAEDAMDIFKVATPADIIKFVVGSMQDLDRMNEILKTYTTEAQIFATIVDYMKAHDNVRFQLQIHKFIWDP 215
324 2.000e-41UniRef50_B9JS44 7-carboxy-7-deazaguanine synthase n=74 Tax=root TaxID=1 RepID=B9JS44_AGRVS  ali  25  14................IRVSEIFPTIQGEGVLIGQPTVFVRMGGCDYRCSWCDSLHAVESRFREEWL----------PMSVQAIWAEVESLS--GGVPLMVSLSGGNPAIQPLGALIAHGHERGYRFALETQGSIDWFADLDVLVVSPKPPSSGMETDWDALSLQSPLTVLKFIVFDEADYAYAHTPPPPEDDDARMHWLVDRVVED--RWRVLPQLHVLLW.. 249
325 2.000e-41UniRef50_A0A2V6R7I5 Uncharacterized protein n=4 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6R7I5_9BACT  ali  26  26.................RVSEVFASIQGEGPSAGTPSVFVRLQGCAVGCAWCDTKYSWN-------------AAGGRATTLDALLAEVKA-----GAASNVVVTGGEPLEHPLGPLVAGLKGLGLRVEVETAGTELPPP----VAVDWNVSLKLAHSGVPEARRLRPAAIARF-RDLGAWFKFVVVLLMPLEEQEALMPAVVEWCRRH-GFRFSPRLHILLWGP 236
326 2.000e-41UniRef50_UPI0003645F80 7-carboxy-7-deazaguanine synthase QueE n=1 Tax=Desulfurispora thermophila TaxID=265470 RepID=UPI0003645F80  ali  26  1........MSTGSAM---VREVFSSAQGEGPLVGVRQIFLRLAGCNLHCSYCDTRYQHPLPGQDSQVVWQEL---PNPLAVSRVLEIIQTLDPASHHSLSV--TGGEPLLWADFLCQLLPGIRGFRVFLETNGTLPVLSLLRWVSMDIKLPCYLGGREYWEIRLAREKDLVKVVVGDDAPLDFRQLVIQPLTSPARALQLQAMALAMLDDVRLVPQTHVFLGL. 249
327 2.000e-41UniRef50_UPI000A03D2B9 7-carboxy-7-deazaguanine synthase QueE n=3 Tax=Thermoproteaceae TaxID=2267 RepID=UPI000A03D2B9  ali  25  1................MKIVEIFRSRQGEGPNAGKEAVFLRLALCNLRCVWCDTKYSW---------------RGGVDMSVYDV---CSRLMSIGNEVRHLVITGGEPLLWLDEPLLRMIKSLGWYVEVETNGTIPPNGLVNYV-DEFNVSPKLSNSGLPMRVRINELAVREFVISGKAVFKFV---IENQKDGEEVLWFINKFGIPRDRIYLMSQ........ 180
328 2.000e-41UniRef50_A0A2H9PD25 7-carboxy-7-deazaguanine synthase n=3 Tax=Candidatus Desantisbacteria TaxID=1819803 RepID=A0A2H9PD25_9BACT  ali  24  3...............KGWLCEIFDSIQGEGIYLGVRQIFLRFAGCNLRCEYCDTPQARHKYCRAMSHESCVMSKIENPMTVDSIIFILKSYYPGSNIYHSVSLTGGEPLLQVDFILIPQLKKLGLKIYLETNGVLPIVDEVDFIAMDIKLPTAIGQKLWKEHKKFLKQCAMNYILDRKAPV-FVKIVITPRTSGGEIKKAAELIAEVNREIPLVLQ........ 222
329 2.000e-41UniRef50_I0GSQ1 7-carboxy-7-deazaguanine synthase n=27 Tax=Selenomonadaceae TaxID=1843491 RepID=I0GSQ1_SELRL  ali  22  1..............MKENLIEIFSSIQGEGKYVGCRQVFVRLEGCNLDCTYCDTPGSHPTCEVETYAGSREFASLPNPRSAEQVAMEINRLCKEV-PHQAVSFTGGEPLLHAEFI-REVAKEVEVPIFLETNGTLSLMDVADIISMDIKLPSIVSQPQWEAHKKFIEVAYIKLVVADETTEEFIIQPVTPYGSPEKILMCQNYALTKLKDVRVIPQTHKMIG.. 241
330 2.000e-41UniRef50_A0A2I0QDN0 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Altiarchaeales archaeon HGW-Altiarchaeales-3 TaxID=2013675 RepID=A0A2I0QDN0_  ali  20  7.................HIREIFSSTQGEGIYPGVRQIFIRFPLCNLNCDYCDTPSKELPDFCNVETTPGCGNFKKNPISVEGIIEIINDLKTN--DLHSISLTGGEPLLYPGFIKELRNQTK-ISFYLETNSTIPIKTCVDFVAADIKLDNEFYKNSLETIKILKDRNFIKIVVNQRIDVPLVLQPVTPYPDAERLFELADICGKHLTDVRIIPQMHKIWGV. 241
331 2.000e-41UniRef50_A0A2M8D1F2 7-carboxy-7-deazaguanine synthase n=1 Tax=Acidobacteria bacterium CG_4_9_14_3_um_filter_49_7 TaxID=1973888 RepID=A0A2M8D1F2_9BACT  ali  20  1................MKVNEIFATIEGETSLTGIPMLFVRFTGCPLRCTYCDTTYAY---------------EDGAEMTIKELLTIIEN-----NGLPIVHLTGGDPLAQVELPLVKRLLENNRQVILETGGSMDIAPFVVRIMLDVKTPGSGMHSCLSNIPLMRERDEFKFTLCHREDYDWAVDFISEHRLTEKPAELADWILKDRLPVRLNCQLHRFIW.. 207
332 2.000e-41UniRef50_A0A257W3C9 7-carboxy-7-deazaguanine synthase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A257W3C9_9SPHN  ali  21  14....................EIFASLQGEGPSIGRPSIFVRLSRCNLACRWCDTAYTWRFTGDNRPHRDDLAFERSANQVVLDEADVAAMILAF--PEDRLVVTGGEPLLQGAALGRLLGLRPGLHVEIETNGSVAPVTAVDGLVDQYNVSPKLAHSGNPAELALVPERLAEWARDGRAFFKFVVATPGDL---DEIAELAARFGIAGERLFVMP......... 207
333 2.000e-41UniRef50_B3E1R2 7-carboxy-7-deazaguanine synthase n=7 Tax=Desulfuromonadales TaxID=69541 RepID=B3E1R2_GEOLS  ali  24  1......MPVPNTMNSSAPLVEIFSSLQGEGVLAGYRQIFVRFPGCNLDCSFCDTDEAQTACRVETTPGSGQFQELAQPVSLETLLGIITRWCKQLPNAHHISITGGEPMLHADL-LARWLPELNIPIHLETNGTLPLIEHLDVISMDIKLPGSAATELWQEHKRFLEIALEKLVAELDDEIPFIIQPVTGRDGPERLMQFQAVAAKRLCDVRVLPQMHRFL... 251
334 2.000e-41UniRef50_A0A1G1KLS8 7-carboxy-7-deazaguanine synthase n=8 Tax=root TaxID=1 RepID=A0A1G1KLS8_9BACT  ali  23  2............NTPRAEITEIFSSIQGEGIFGGARQIFVRFKTCNMACEFCDTP----------------NDGAAKEYSPTQLMNEIKILDEAKGAHHSVSLTGGEPLVYTEFLFLPLLKKAGFKSYLETNGTLPIIEFTDIVAMDFKLPSSTGGREYWKEH----SEFLKIAARKKVFVKAIVTANTSKDDIEKAALLIRQVNKNIPNSRVIPQMHKILGI. 233
335 3.000e-41UniRef50_A0A1V5VKX9 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1V5VKX9_9BACT  ali  22  1..............MIGRIFEMFVSVQGEGILAGEQMLFVRFSGCNLNCDYCDTEE-------------CRHAISGRLLTHEEIIREIEDMLAQNPSVGTVSFTGGEPLLQSELILTQYLKEKKIKIYVDTNGTLNIASNVDCVAMDIKLPSSGGMEFWEEHKKFLENIFVKIVLTSKTEFKKAVEMVERVNNLPENLERFKKIAKRLKKVSIIPQMHKKWGI. 230
336 3.000e-41UniRef50_A0A2E2I8L3 Multifunctional fusion protein n=1 Tax=Euryarchaeota archaeon TaxID=2026739 RepID=A0A2E2I8L3_9EURY  ali  33  181MQLINTKPLXGDYLTTYPIVEIFHSVQGEAFHAGVPHVFIRFGNCNLRCEWXDTDFL-----------------TYEEMELXNIVDEVLSY-----NCKRVIFTGGEPCLQDLETIGKALKIHGINLSVETNGTIKVPEIIDWICVSPK--DQLYQRIGDELKVVYCGQDLTLYDELKDGFXHLFIQPXYFENESKNFAQTENLVKQNQDWRLSLQTHKWMGV. 390
337 3.000e-41UniRef50_A0A1F9ZXE1 7-carboxy-7-deazaguanine synthase n=18 Tax=Bacteria TaxID=2 RepID=A0A1F9ZXE1_9BACT  ali  25  3...............KASIAEIFVSIQGEGLYAGQKQVFVRFAGCDLGCDYCDEPAA---------------KGGGREMPLAAVKKELEALALRDKA-RAVSFTGGEPLLQAGLELARFARRLGLETHLETNGTLWVVKAFDVVAADIKLPGTSGKVFWAEHRKFLKKAFVKVVVTSKTPFKFYIQPVTKPPSEARLDAFYHIAIGKLYTVRILPQLHKLWGI. 227
338 3.000e-41UniRef50_A0A1Y4D9Z7 7-carboxy-7-deazaguanine synthase n=1 Tax=Desulfovibrio sp. An276 TaxID=1965618 RepID=A0A1Y4D9Z7_9DELT  ali  28  4................LFVNEVFVSLQGEGHFTGTPAIFVRLQGCDVHCPWCDTGYARDLRTKDNDFSVLAKETASGLYTSMDPEILCNYLSGLHKSIRHVVLTGGEPFMQDVAPFIRLLQGRGFYVQVETSGTRPLSVYNEWITLSPKMPLAENWSRANEIKIIASEEDADFLLS--EVFERVIIALQPVSQDREATRLCFKLCLKH-NLHLSLQTHKY.... 223
339 3.000e-41UniRef50_A0A149NMX9 4-hydroxyphenylacetate decarboxylase activating enzyme n=55 Tax=Bacteria TaxID=2 RepID=A0A149NMX9_BACFG  ali  20  20...................VEEFAIHDGPGIRT-----TIFLKGCPLRCAWCHNPEGISPQPQYMIKKGVKSIC-GYQITVEELVTMIEKNRSYTLNRGGVTLTGGEPLFQPDFVIELLRQLPDIHTAIETSGFNEVTSLADLILFDIKHTDPEMHRKYTGVDNAIILENLALLCNSGRDFIIRIPLIPGVNDTRENMSAILEKIKDARNIRVILRYHR..... 222
340 3.000e-41UniRef50_A0A2E5UGU8 7-carboxy-7-deazaguanine synthase n=2 Tax=Phycisphaerae bacterium TaxID=2026778 RepID=A0A2E5UGU8_9BACT  ali  22  6................LRINEIFYSIQGESTWVGKPCVFLRLTGCPHXCHYCDTSXA---------------FXEGSKRSVTSILXEIVTY-----PTKLVEVTGGEPLAQKIIPVXKTLCDEGYTVLLETSGSQSLXXVDQRVIVDXKTPHSGASFDMENLHXLTAQDEIKFVITDKEDFDWVVETVQSXXLFDXVKALAXWVLESGLPFHCHLQLHKYIWSP 223
341 3.000e-41UniRef50_A0A290QC01 7-carboxy-7-deazaguanine synthase n=2 Tax=Verrucomicrobia TaxID=74201 RepID=A0A290QC01_9BACT  ali  23  1................MLISEIFYSLQGEGVLTGVPSVFVRAAGCNLRCNWCDTPYASWKP-------------EGETRSVAEIVTEISR-----HPAKHVVLTGGEPMIAKEIELAGEVKKLGYHITIETAGTVAPEGICDLASISPKLKNSAPDERLPDAWRERPEVVRAWIDAGDYQLKFV---VSSAADVQEIEEMLAELGRDIPRAKVLL......... 187
342 3.000e-41UniRef50_A0A017RXG3 Pyruvate formate-lyase-activating enzyme n=5 Tax=Clostridiales TaxID=186802 RepID=A0A017RXG3_9CLOT  ali  16  3...............TGRIHETMGLLDGPGIR-----VVVFMQGCRLRCAYCHNPDTWDT-------------KGGFEITAEELLKKVRRYKVYFKSGGGVTLSGGDPLMQPQFEFFKLCREEGIHTTLDTSGYDEVLKYTDLILLDIKHIDDAAHKQLTGLGREGFLQFLEAAKSNGNKIWIRHVVVPGITNGREHIKKLAEFINTIPNVRVLLPYH...... 199
343 4.000e-41UniRef50_A2BJ90 7-carboxy-7-deazaguanine synthase n=4 Tax=Pyrodictiaceae TaxID=2307 RepID=QUEE_HYPBU  ali  26  16................LRVVEVFASIQGEGPFTGTYSVFVRLAGCNLRCPFCDTRYAWSLE-------------AGKPLGVEELVEEIARYEP-----SLVVITGGEPLLQPLNSLVEGLESLGLRVQLETNGILPAPAWRVYHVVSPKVPGAKLHPSWVDYARATGRAWFKFLVANGIPRSRVYIMPPEKLDMKELLELHSRIASLAVKWRLSPRLHLLVQLP 235
344 4.000e-41UniRef50_H3KD59 7-carboxy-7-deazaguanine synthase n=1 Tax=Sutterella parvirubra YIT 11816 TaxID=762967 RepID=H3KD59_9BURK  ali  26  1MTPIVPTARQKGAEPLFFVNEIFASLQGEGAWTGTPSVFVRLQGCLCRCPYCDTKHTWKLGEPNGEKLDFAAAKADAPRHATATEDELDFITTHFPKVPHVVFTGGEPFLFDLTGISERLLAAGRTVGVETSGTEPAVAGAVWVTVSPKIGMPGGRVVLPET--LARADEIKMAVESEKDIEELKTDVLPFVSKKALIERATKFCWDAEGWRVSFQVHKY.... 234
345 5.000e-41UniRef50_W0P5N6 7-carboxy-7-deazaguanine synthase n=4 Tax=Enterobacterales TaxID=91347 RepID=W0P5N6_BUCMP  ali  22  1..............MNYPVNEIFQTIQGEGYYTGTPSIFIRLQGCPIHCPWCDTKYTWTCKNKISSEEIIKKNTSNQQWSLMNVEQILLNIKIKKWTAKHIVITGGEPCIYNLLHLTETLEKKGFRCQIESSGTQLIQSLNTWVTISPKRSNEIKYPILKKEDLSYLDKILSMVKNKKKCY----VSLQPISQNKEALEICIKTCI-MKNWKLSIQLHKYILI. 218
346 5.000e-41UniRef50_A0A1F4U5I7 7-carboxy-7-deazaguanine synthase n=1 Tax=candidate division WOR-1 bacterium RIFOXYC2_FULL_46_14 TaxID=1802587 RepID=A0A1F4U5I7_9  ali  21  4................AQLHEIFSSIQGEGLYVGDRQLFIRFSGCNLSCDYCDSKEALTLQPQFKV----EDKKIDNPVTAEKLLEIVSSFTKNKNLHSAISITGGEPLLQVDF-LAKFLPELKIPVYLETNGTLPIINHVNIISMDFKAGHAKEHFHFMEIAYTSGKEFVKFLISQISPLIPLVLQPLHPIKIKKDQLLSFQAVAKRKRVKIIPQVHKILHM. 229
347 5.000e-41UniRef50_B8CX38 Anaerobic ribonucleoside-triphosphate reductase activating protein n=3 Tax=Halanaerobiales TaxID=53433 RepID=B8CX38_HALOH  ali  20  1..............MKIAGLQKTSLID----YPEKISTVVFTYGCNLRCPYCHNSGLVKNNNKNIDFISLDLLF--------------EFLRRRKKLIDGVCITGGEPTLQTLEPFIRKIKKMGFKIKLDTNGTKPDLNLIDYIAMDIKAPFSRYGLLAGSSKNNQIKESINILLNSNIDYEFRTTVIPGYHTENDLIKIA-ELIKGAGRYFIQ.......... 190
348 5.000e-41UniRef50_I7BQ24 7-carboxy-7-deazaguanine synthase n=6 Tax=cellular organisms TaxID=131567 RepID=I7BQ24_NATSJ  ali  25  28................LPINELFYSLQGEGTLAGVPSVFVRTSGCNLRCWFCDSYHTSWEPTHA-------------RMSLAEILAEIE-----SHDADHVVLTGGEPLLHEGTTLLEALDERGYHTTVETNGTIYRDAPIDLASVSPKLASSGEWEARHETDRIDMDALARLVESYDVQLKFVVT---DDGDMPEIRELLADLRAAADDVLLMP......... 223
349 5.000e-41UniRef50_A0A0F9EBX8 Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=A0A0F9EBX8_9ZZZZ  ali  22  12................LKIAEIFVTVQGEGPNTGIPVVFVRLQLCNLSCRWCDTPYTWNWEGTDFKHDTKDYEQKKYDMTPDEVLNKVKELA--GKNVKRVIWTGGEPLIQQRSYAFIKTLDNGFKIEVETNGTLKPSEEVQPYIDQYNVSPKLENSGNTLKVRRKDKPYEFFTKAPNAYFKFV---VMDEKDMEEIQEIQKQYNIPSSKILLMP......... 216
350 6.000e-41UniRef50_K9TUT2 7-carboxy-7-deazaguanine synthase n=7 Tax=Cyanobacteria TaxID=1117 RepID=K9TUT2_9CYAN  ali  24  3...............TARLIEIFSAIQGEGLNVGTRQIFIRFALCDLRCHFCDSAHTWSVPSTCRVERSPDFETHPNPVPLNTLLTWIER-QNSPGLHDSISLTGGEPLLHAPFLLPLVRRATGLPIYLETGGHRPILPYLDSVGMDIKLPSVSGEDRWNEHHQADIEVFIKAIVSSQTDLEIPVFLQPQAPTPAQVLHWQAMMKRELKQVRVIPQTHKMLN.. 256
351 6.000e-41UniRef50_A0A2A5HVL0 7-carboxy-7-deazaguanine synthase n=1 Tax=Alteromonadaceae bacterium TaxID=1916082 RepID=A0A2A5HVL0_9ALTE  ali  24  21....................EIFHSLQGEGPHLGRPSVFVRFSECNLTCHWCDTPYTWNWQHEHENHKRYDKALEQVTLDVAQLAAEI-----RSFPCQNLVLTGGEPMLQPVLEQLRGETDAPWYVDLETNGTVLPAASFDRYVSCYVVSPKLSNAKVDERQRIKAEAMTWFANSPKAFFKFV---VGDESDLVEIKALVERFNIQQDKVFLLP......... 215
352 6.000e-41UniRef50_A0A1V6HX99 7-carboxy-7-deazaguanine synthase n=1 Tax=Deltaproteobacteria bacterium ADurb.Bin058 TaxID=1852865 RepID=A0A1V6HX99_9DELT  ali  25  1................MRIIEIFRSIQGESSTVGTPCTFVRTAGCNLNCYWCDTRYAM---------------EAGIEMSVLEILGQV-----RQFNTKLVCITGGEPFLQRDLELVNALQSAGYQIQIMTNGTVFLMNSQVSRVIDIKSPPKELESDLSNLKLLSPSDEIKFVARNLVEFQWFLAWAKSVDLFGKGVALVDWILESGLPIRLNLQIHKIIW.. 218
353 7.000e-41UniRef50_A0A1I6I5Y9 7-carboxy-7-deazaguanine synthase n=1 Tax=[Clostridium] populeti TaxID=37658 RepID=A0A1I6I5Y9_9FIRM  ali  21  15...................VEIFQSIEGEGTKAGTPTTFIRLFGCNLRCSWCDTKYSYEPD------------KPRFYASVEQILEQATTY-----GSSSVCLTGGEPLLSFKLLLGLGELDFIKDIHIETNGSIDLTPYCKLFVVDYKPISSGQNEKMNNFSLLSNRDEIKFVIGSEEDFLLARTVISPLWGKIEPARLVSLMLSKLLHARLSLQLHKMIW.. 230
354 7.000e-41UniRef50_A0A1V5JH81 7-carboxy-7-deazaguanine synthase n=1 Tax=bacterium ADurb.BinA028 TaxID=1866933 RepID=A0A1V5JH81_9BACT  ali  28  5................LPVSEIFPTIQGEGEHIGRRAVFVRLAGCDSRCSWCDTKYAW-------------GTEGATHMSEDEIVDAVSGL----GPCRLVVITGGNPAMYDLERLVTLLALRGKTVHVETQGTIRWLRLADLVTISPKADLPNALSDLVCDLLGCTSVQIKVVIHSRADFDRAVEIGRRLPAVPLILQLASWFARDGPSARLLPQLHRVLW.. 217
355 8.000e-41UniRef50_B8IAL9 7-carboxy-7-deazaguanine synthase n=17 Tax=Proteobacteria TaxID=1224 RepID=B8IAL9_METNO  ali  27  1..............MTFAVNEIFETFQGEAAFTGTPSVFVRLQGCPVGCAFCDTKMTWHVRPEHEIEVGAMIAKTEDAPTWARLHDEDLAMLVGEFRARHVVFTGGEPALYDLTEVSRRLIDQGRTVQLETSGTALIIDPHAWVTVSPKIDMPGGLKVLPAA--VARANEIKMPIGKPADIEKLLIWLQPLSQSEKATALCMEAAAAN-GWRLSLQTHKFVGV. 229
356 8.000e-41UniRef50_A0A1F6RN25 7-carboxy-7-deazaguanine synthase n=3 Tax=root TaxID=1 RepID=A0A1F6RN25_9BACT  ali  23  7.................NIIEIFSSIQGEGPYIGYRQLFIRFALCNLNCAYCDTAFSPEEYCKIEVCPGSGSFKVKNPVTVEQLIHEIDRLNYFHH--HSLSLTGGEPLLNSEFIIQEIKANNNLKIYLETNGTLSVIKNIDIISMDFKLESSYGKTAPWDKHREFIEIFAKVVVTSKIKPEEVSQIISLIPEPVKVMEIQEALLKKLTDVRVIPQVHKYL... 250
357 9.000e-41UniRef50_A0A1N7SJF1 7-carboxy-7-deazaguanine synthase n=117 Tax=Proteobacteria TaxID=1224 RepID=A0A1N7SJF1_9BURK  ali  26  15...............TYPVNEIFESLQGEASFTGTPSVFVRLQGCPVGCPWCDTKHTWQVIPEREISVGAMGEKTEQPCDSYAWCDVTLANIVRAADAEHVVITGGEPCMYDLRPLIAKLEAWHHRVQVETSGTYPLVTPSTFVTVSPKVLDEALARANEIKHPVGKQREINIVLEKLDPIHQARIWLQPLSLSSRATGICIQ-AAHRYGWRVSLQTHKFINI. 234
358 9.000e-41UniRef50_A0A1V5R9B7 Pyruvate formate-lyase-activating enzyme n=12 Tax=Parcubacteria group TaxID=1794811 RepID=A0A1V5R9B7_9BACT  ali  18  1..............MLIGGLQKFSLLD----YPGHVTAIVFTQGCNFRCQFCYNPMLVWPPEVGKLKNSFSSKNEGKGHPLIKEGDLFDFLKSRMGKLDGVVVSGGEPTIQRDLPFLAKIKELGFKIKLDTNGTSPAKKLVDYIAMDIKAPAEKYEKVTGVKSNFKIKESIKIIRESGLPYEFRSTTVPGLHSAEDIRKM-GELIRGADKWFLQI......... 207
359 9.000e-41UniRef50_A0A1V5XC71 Pyruvate formate-lyase-activating enzyme n=46 Tax=Bacteria TaxID=2 RepID=A0A1V5XC71_9FIRM  ali  17  1..............MRGRVHETLGALDGPGIRT-----VVFMQGCPLRCAYCHNPDTWN-------------AKGGVLYTPNELFERVKRFKPYFKSEGGLTLSGGEPLLQGDFEVLRLCRNEGIKTAIDTSGYIEAVDLADLIILDIKHTSPERYKALTGADIEKSFEFLDYCKKTHKPLWIRQVILTGINDTKEDMEALKSLIKGA-NVKLLP-YHKM.... 196
360 9.000e-41UniRef50_T0Z7Y3 Radical SAM domain-containing protein (Fragment) n=2 Tax=mine drainage metagenome TaxID=410659 RepID=T0Z7Y3_9ZZZZ  ali  28  1..................ITETFKSLQGEGPFIGIPMFFVRTNRCNLRCAWCDSTYT---------------FYGGHEVSVDDLLEQV-----NTSGADWVCFTGGEPLLQREVDFVRKLSESGTKVLIETSGSLPIKEYTAFIDMDIKTPSSKEESSLDNLYVLRKQDYVKFVISDEVDYDYAKRIIPGLP................................ 161
361 1.000e-40UniRef50_A9CF16 7-carboxy-7-deazaguanine synthase n=504 Tax=root TaxID=1 RepID=QUEE_AGRFC  ali  23  1MTEAARNIAARET--TVRISEIFPTIQGEGPLIGLPTVFVRTGGCDYRCSWCDTLHAVDSEYRDTW----------KPMSVEAIWQEVLGLSGGMPL--TVSLSGGNPAIQPLGTLIAKGQGEGYRFALETQGSIDWFADLDHLVLSPKPPSSGMETDWQAFEDDGPQVALKVVIFARFPHLPVYLQPGNHTPPDRMLWLVEKISEDRFSARVLPQLHVLLW.. 245
362 1.000e-40UniRef50_R7NCB3 7-carboxy-7-deazaguanine synthase n=6 Tax=Bacteria TaxID=2 RepID=R7NCB3_9FIRM  ali  25  2............SKQIFNVVEHFASINGEGVRAGELAVFVRFRGCNLDCSYCDTRWA------------NDVNAKAAKMSVSDIVKAVEDVK-----IDNVTLTGGEPLIQAIDKLIAQLLISGRNVEIETNGSIDIENVKDNLTLSMTADYKLAGSNMDNFNNLQSQDTVKFVVSSEEDLKRALEIIRQYNLTEKCIETIVDFMKDNLGARVQLQLHKFIWSP 242
363 1.000e-40UniRef50_A0A2V3A6T4 Pyruvate formate lyase activating enzyme n=2 Tax=Bacillus oceanisediminis TaxID=665099 RepID=A0A2V3A6T4_9BACI  ali  16  23..PRRSVLIERKIIMYGNIHETFGTVDGPGIR-----YVIFTQGCLLRCQFCHNADTW-------------EIGTGKQMSVSEIMDDLQSYLPFIESGGGITVSGGEPLLQFIIELFRECKQLGIHTAIDSSGLKELMGYTDLVLLDLKHIDKEKHKKLTGLTNEHILQFANYLSDSHVPVWIRHVLVPTISDEEKDLERLGQFIKGLENVKKILPYHKL.... 241
364 1.000e-40UniRef50_A0A1M6QZX7 7-carboxy-7-deazaguanine synthase n=1 Tax=Paramaledivibacter caminithermalis DSM 15212 TaxID=1121301 RepID=A0A1M6QZX7_9CLOT  ali  21  1................MKVSELFYSIQGETTLVGEPTYFIRLYGCNLRCNWCDTKYSY-------------EKNSYIEYSVEQIYNLVKKENP-----TNICITGGEPLLQYEEVISVIDLFVNKTISIETNGSIDISKITERIVMDYKLSYEINNMNTNNFKFLRDTDEIKFVISDYNDYKKGKILIGFVAGTIQPKEIAKYILKNKLDWRINYQLHKLIW.. 212
365 1.000e-40UniRef50_A0A2H5WJ22 Pyruvate formate-lyase 1-activating enzyme n=6 Tax=Bacteria TaxID=2 RepID=A0A2H5WJ22_9BACT  ali  20  27......................FTLID----YPGKVSCIVFTQGCNFRCPYCYNVELVLPE------------YFGKTIPEEEI---LSFLEQRVGKLEGVVITGGEPTIHALKDFIEKVKKLSFSVKLDTNGSMPEVRLVDYIAMDIKAPPDKYEEVVRAKVNIKINRSINLIMNSGVDYEFRTTVVKDQLSKDDILKIAEWI-KGAKRYYLQ----KFL... 210
366 1.000e-40UniRef50_A0A1M6II99 Pyruvate formate-lyase-activating enzyme n=4 Tax=Clostridia TaxID=186801 RepID=A0A1M6II99_9CLOT  ali  16  11....................ETCGTVDGPGIR-----YILFLAGCPLRCKYCHNCDTW-------------KKNVGELMTVEEIIADVIKYKPYFKFSGGITVSGGEPTLQWLGELFKLCKAEEIHTCLDTSGYCDLLPYTDLVLLDIKHIDNEKHKALTGVENHKTLAFARHLRDRNIPVWIRYVVVPGYSDDPLDIEKLCRFLKTLDNIRVLLPYHKM.... 203
367 1.000e-40UniRef50_A0A1J4VD65 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A1J4VD65_9BACT  ali  23  5...............KAKVSEVFSSIQGEGPYLGRRETFVRFSDCNLNCVFCDV-----------------EQKKEKFYTAGELIKRIKEIAQRTK---WLTLTGGEPLLWSDFELLPLLKQQGYKITLETNGTLPIKSLISLVSLDFKLPSSTGEKPFWKEHLAKEKSFVKTVITSGIDQKIPLILQPDVPRIKKVLQFQQEALKFISDVRTIPQMHKFL... 225
368 1.000e-40UniRef50_Q7V9H9 7-carboxy-7-deazaguanine synthase n=70 Tax=Bacteria TaxID=2 RepID=QUEE_PROMA  ali  25  5................LPIVERFHSLQGEGLHFGKSAFFIRLGGCKVGCPWCDTKESWSIATH-------------QEATVEELSKEAA--IAQSQGAAILVITGGEPLHHNLNALCKTIQDETMPIHLETSGVDEITGLINWITLSPK------RHALPKKSLLRACDEIKVVIHQKEDLLFAHLFLQPGWNSKEGTQLTIEYIKSHPQWRLSLQTHKWLGV. 224
369 1.000e-40UniRef50_A0A1G1PZ46 7-carboxy-7-deazaguanine synthase n=1 Tax=Omnitrophica WOR_2 bacterium RIFOXYA2_FULL_38_17 TaxID=1801873 RepID=A0A1G1PZ46_9BACT :  ali  22  1..............MKAKISEIFRSIQGEGKYLGVSQVFVRFAECNIDCIWCDTDFTVKEQL--------------------DEVELIKRIKGLMPGCHSLSLTGGEPLVQIKFIFLPMICKEGINIFLETNGTLQVLKYLDIVSMDIKLPS----SAGCGEHWQEHSDFLKIAVGSKKDVKIVVTQQPEFIQRDGLMQKCQEYLGQLNDVRIIPQVHKLMG.. 222
370 1.000e-40UniRef50_A0A1W6K187 7-carboxy-7-deazaguanine synthase n=1 Tax=Acidianus manzaensis TaxID=282676 RepID=A0A1W6K187_9CREN  ali  23  4................YRVIEIFTSIQGEGNVIGTPSNFIRLATCNLRCLWCDTKYSW---------------EKGELMSITDILSQL------NHKIKVTTITGGEPLLQNITPLAKELKNINHTIIVETNGTIELRKIIDVFSVSPKLSNSGYYKFVITNPEKDLKELSDFVASQRIDPKKVIIQPDGNREISALKELSDFVIKLNLPFRVLPQLHRII... 207
371 2.000e-40UniRef50_A0A2H0S878 7-carboxy-7-deazaguanine synthase n=3 Tax=unclassified Candidatus Peregrinibacteria TaxID=1801912 RepID=A0A2H0S878_9BACT  ali  25  1................MQVSEIFYSVQGEGPNIGMPAIFLRTAGCHLRCVWCDSKFTW-------------ERTSGKKMTTNEIIKELKKF-----PCKHLIITGGEPLIQQSAIKELLEKLKDYYIEIETSGSL--KSYLDDYVNHYNCSPKLSNSKNKTIRLEKLPDE-------KTVYKFVV-------DSPKDLKEIKEFIKTNKNVVLMPQ........ 170
372 2.000e-40UniRef50_G7WN61 7-carboxy-7-deazaguanine synthase n=2 Tax=Methanosaeta harundinacea TaxID=301375 RepID=G7WN61_METH6  ali  26  3....................EIFSSFQGEGPLLGRRQVFVRTAGCNLACAYCDSAKFRREVTFCDVIAPGLRRRAENPVSLAWTMEEVRALWGRG--THSVSITGGEPLCQPEFALARACSAEGMPVYLETNGFSKMIPWIDIAAVDIKLP-SAFSRGGSEELVENELASIEAASRRGV-FTIAKVVVDGRPSPEKLTELFEAAAEVLSGVVVIPQAHKMMGI. 238
373 2.000e-40UniRef50_R5KRJ9 Pyruvate-formate lyase-activating enzyme n=10 Tax=root TaxID=1 RepID=R5KRJ9_9CLOT  ali  20  14...............................FPDKISAIVFTQGCNFRCGYCHNPELIVLR---NEPAWTKAGF-------------LEFLISRKGKLDGVVITGGEPCLQNDLIFIKEIKAMGFLVKLDTNGTFPDLPYLDYIAMDIKAPLHKYSEITKNINTDKIEKSINLIMNSGIDYEFRTTVVKSQLTFED-FEDIGKLIKGAKKYYLQ.......... 186
374 2.000e-40UniRef50_A0A2E0U7X6 7-carboxy-7-deazaguanine synthase n=2 Tax=Ponticaulis sp. TaxID=2020902 RepID=A0A2E0U7X6_9RHOB  ali  22  17....................EIFASVQGEGPSLGSPRTFIRLSGCNLHCVWCDTAYTWNWEGTAFDHETGRKFAPENEQTIDEIVSRVADTSP-----SGIVITGGEPLMQKLAPLITAIKEAPVWVEIETNGSVLPTRDLIPLINQFNVSPKLSHSGNDMAVAQREQSLTAFAALPSSWFKFV---ISEPGDVEEVLRISDRYKIAHDRVFLMP......... 210
375 2.000e-40UniRef50_F4KJI7 7-carboxy-7-deazaguanine synthase n=22 Tax=Bacteroidetes TaxID=976 RepID=F4KJI7_PORAD  ali  30  4................LPVNEIFYSLQGEGGQMGRAMLFVRLSGCNLTCDYCDTDFA-----------------GHQLMTASEILAQL-----GSYPCRDILWTGGEPTLALREEHIAFFHEHGYRQSIETNGTRPMPQGLDYVTCSPK---PEAISGLRERFVDNYIDEVRWPLQLGAPLYYVSPVEETGVEMSAVVARCMDFVLAHPEWRLSVQLHKLLG.. 199
376 2.000e-40UniRef50_A0A2E4MXY3 7-carboxy-7-deazaguanine synthase n=2 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E4MXY3_9BACT  ali  26  16........PVWNDGQTLQVNEIFYSIEGEGVRVGQPTTFIRLSKCNLRCFFCDT-----------------EFDSFTEMSIRKIVEEV-----RMHSAEWVSLTGGEPIGQNIAPLCERLLGNGYRLHIETSGSLTPQAELFELIEHWTVSPKRGFERITELKYVVGKAFREMIEGDRSDL----VYLQPESSKPEYVIKTLEILQRHPGWRLSCRIHKMLHLP 211
377 2.000e-40UniRef50_A0A2D9M054 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A2D9M054_9CHLR  ali  41  2................YVIKEIFATLQGEGHNAGTPAVFVRFAGCNLWSGREGTRGADAKENTAECALWCDTFVNGERVTLEDIAERVISAAGEAGMISGVVFTGGEPLLQLDRDLLMTGRSRRRPIAIETNGREEVRELLDWVCVSPKNPGDLKVRKGDEFKVIYPADPAIFEGESDLDFKYWYLQARASINAADVMREVALYCIKNPRWRMSVQIHKLLNLP 241
378 2.000e-40UniRef50_A0A2M7YWA5 7-carboxy-7-deazaguanine synthase n=1 Tax=bacterium CG_4_9_14_3_um_filter_65_15 TaxID=1975567 RepID=A0A2M7YWA5_9BACT  ali  21  2................LMINEIYAAICGESRFSGFPCTLVRLSGCHLRCAWCDSPHS---------------FNGGEPMSAEAILDRV-----RANGFRTVLVTGGEPLLQKNVEFLRLLVEDGRTVVLETSGADPEVPQGVHRIVDVKAPGSGIDPDWEGIALLGAGDEVKIVVAGREDFAWVKQLLQSGRLPADPARLAEWILADGLDVALQIQLHKALW.. 211
379 2.000e-40UniRef50_A0A1I2V257 7-carboxy-7-deazaguanine synthase n=1 Tax=Halopelagius inordinatus TaxID=553467 RepID=A0A1I2V257_9EURY  ali  25  1MPVTSTVERPAPDGPALPVNELFASLQGEGKLAGVPSTFVRTSGCNLRCWFCDSYHTSWEPTHA-------------WLSVDRIVEEVAARDP-----THVVLTGGEPLLHDATTLLERLAAEGYHVTVETNGTFAPDAPMDLASVSPKLSDPGEWEARHEARRIDFAALTTLLERHEAQLKFVVTDPDDMAEIDALVADVRE..................... 200
380 2.000e-40UniRef50_A0A259UPV2 7-carboxy-7-deazaguanine synthase n=1 Tax=Sporomusa acidovorans DSM 3132 TaxID=1123286 RepID=A0A259UPV2_9FIRM  ali  24  2................INIVEVFSSIQGEGLYVGTRQVFVRLAGCNLACTYCDTPHTVKNALVERTPGKRDFAQLPMQFSIDNLARHINSLLAV--PHHSISLTGGEPLCQAIAELLPQLKA---PLYLETNGTLFVLPYIDIISMDIKLPTVTDKPYWQEHKEFRKNVFVKIVVTGKVDHHIPVILQPEAVLPDVLLFYQEKALTLLNDVRVIPQTHKFMG.. 239
381 2.000e-40UniRef50_A0A2U8DGD0 7-carboxy-7-deazaguanine synthase QueE n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A2U8DGD0_9GAMM  ali  24  1..............MKYPVNEIFQTIQGEGYYIGTPAIFIRLQGCKVACEWCDTKYTWKNSYENQIEEIIKKEKSNKKWSYMTTQNIILIIKQLKWTAKHIVITGGEPCMYNLLDITTLLEEKGYFCQIETSGTELIESLNTWVTLSPKQKNEIKFPILIEQDFLYLKKILHMIKKRKNNLIF----LQPISQNEKALAICIKKCTE-KNWRLSIQIHKYLQI. 218
382 2.000e-40UniRef50_A0A2D6DPY5 7-carboxy-7-deazaguanine synthase n=1 Tax=Parcubacteria group bacterium TaxID=2026774 RepID=A0A2D6DPY5_9BACT  ali  25  25...............RLLISEIFYSVQGEGITVGRPSVFLRLGSCNLHCVWCDTAYTWDWNRYNNE-------KELVFMNKDDIRDRVLRYRCRR-----LVVTGGEPLLQALVELLNDLKERDFYIEIETNGTLRPIAPLVAITDQWNVSPKLKNSGNSEEDREQKSCYRVFSSFSGSFFKYVIQNPEDVTEVD---GLVARYALNKERVILMP......... 211
383 2.000e-40UniRef50_B9M258 7-carboxy-7-deazaguanine synthase n=7 Tax=Bacteria TaxID=2 RepID=B9M258_GEODF  ali  21  2............NKSSADLIEVFSSIQGEGLLVGLRQVFIRFSGCNLTCSYCDTEPDRTQYCQLESTPGRRDFFVENPVPVDRLVNLVSGWQRGWPGIHHISITGGEPLLHQLLQELLPALRHYLPIYLETNGILHLLDHVDYVSMDIKLPSTSGYTDLW----QAHEEFLRLAASKKTYVKTVILILQPFTDLKRMLEMQETANRYLQEVRIIPQTHKFIG.. 247
384 2.000e-40UniRef50_A0A2H0P2P0 7-carboxy-7-deazaguanine synthase n=1 Tax=Elusimicrobia bacterium CG11_big_fil_rev_8_21_14_0_20_64_6 TaxID=2014311 RepID=A0A2H0P2  ali  26  36.....TGTLKLSDEARARVVEIFSSLQGEGPRLGERQIFVRLGGCNLHCDYCDEPDTIPIP-------------SGLVKSAEWVKSEIETLAHAR-AHHTISWTGGEPLLHPQFPLMRWAHKKGLANHLETNGTLPVPPLCDAVAMDIKLPSSTGRETWDFLRVVPRNTFIKVVLSDRTEAEWTKVVVKPIPAARRFEALARRAVKE---VFVRPQWHHLWNLP 273
385 2.000e-40UniRef50_UPI000A109B89 7-carboxy-7-deazaguanine synthase QueE n=1 Tax=Thermoactinospora rubra TaxID=1088767 RepID=UPI000A109B89  ali  22  1..............MNLLVTEIFPTFQGEGPSTGQQAAFLRLSRCNLTCAWCDTPETWDTTRYDLSAIT-------RRMSESEVLHEVLAI-----PAPLVVITGGEPLLQQDKLLVDMLRAHGRRTEVETNGTVAPEAGLLTAVKGWNVSPKLANSHLPYARRINPEALEVFTRSRKAVFKFVV-------DSADDLEEIARLEAELAPIWVMPQ........ 188
386 2.000e-40UniRef50_UPI000BE42A55 pyruvate formate lyase-activating protein n=1 Tax=Clostridium peptidivorans TaxID=100174 RepID=UPI000BE42A55  ali  16  3...............KGYIHETMGLVDGPGIRT-----VVFFQGCVLRCAYCHNPDTWS-------------FEGGQEVSPQELLSKVLRFKPYFKSGGGVTCSGGEPLMQPLLEFLKLCKENNIHTTIDTSGYEEILKYVDLVLLDVKHYDRDGYEQITEHSMDKFNEFTESILKSNVPIWIRHVVVPGITDSEEHMIELKKFIKNLEKVELLP-YHKYLGIP 212
387 2.000e-40UniRef50_A0A1F9K350 7-carboxy-7-deazaguanine synthase n=27 Tax=Bacteria TaxID=2 RepID=A0A1F9K350_9DELT  ali  21  1................MRISGLFYSIQGEGALLGAPSTFIRTSGCNLRCVWCDTPYTSWKP-------------EGEDWSIHEILAEVKR-----HPTSHVVVTGGEPLLAPEEELTVRLKKTDYHITMETAATIFKPIACDLVSMSPKLSNSTPWKRMHEERRLDFPVIQRFVDGYDYQLKFV-------ADKKKDFAEIERVLKSLKNV............. 178
388 2.000e-40UniRef50_A0A2E4J8Q8 7-carboxy-7-deazaguanine synthase n=2 Tax=Flavobacteriales bacterium TaxID=2021391 RepID=A0A2E4J8Q8_9FLAO  ali  29  2................IPIKETXLSIQGEGXYAGXSAXFIRTQGCDIGCHWCDEPXSWKXSXXKERTSXSXVXDLXKTXT------------------KIVIFTGGEPLMHDLTEFSKTLTKKGYQLHLETSGAYPLTGKWDWITLSPKVKPPLPE-------IYSYSSELKIVIYNQNDFEWALEQQPEWSKLDVIKPKILDFISNNPRWKLSLQMHKYLNI. 196
389 3.000e-40UniRef50_A0A2N2FY90 7-carboxy-7-deazaguanine synthase n=1 Tax=Deltaproteobacteria bacterium HGW-Deltaproteobacteria-4 TaxID=2013754 RepID=A0A2N2FY90_  ali  25  1MSGNLILPARVTPLSSAMVVEVFSSIQGEGLHLGRRQIFIRLADCNLSCAYCDTEFFRASLFPSEIRPGCGFSTDENPVPVYEIAELVAGWRDLPGAHHSISITGGEPLCQADALAVWLPELRKIPIHLETNGTLPLLGEIDFISMDFKLSVTGVPTPWEEHKRFLALAQVKLVVGPQTSFDFIHEIAPDVPMILQLLEMQALAAAIHHDIRVIPQVHHFLNAP 259
390 3.000e-40UniRef50_UPI0009E70AFB 7-carboxy-7-deazaguanine synthase QueE n=1 Tax=Kitasatospora sp. MY 5-36 TaxID=1678027 RepID=UPI0009E70AFB  ali  22  14VGPSSAEQRRNRRVMK--ISQVFPTVQGEGSAAGRHCLFVRTFDCNLECNFCDTAYTWAVTDEKKRYERDEPLYGLKHMDAAAVLDRLRALWDIEHRPTIIVISGGEPMMQQLVPLLEQLRGWGHEVHIETAGTIAPLAEFNELVTQYNVSPKLASSGNRLSKRFKPEALAALRDSGRAWFKFVVTEDWE-TDLAEIDRIVVDVALAPQRVMVMP......... 235
391 3.000e-40UniRef50_A0A1G2X6W8 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Planctomycetes TaxID=473814 RepID=A0A1G2X6W8_9BACT  ali  26  1................MRITELFYSIQGEGLLAGKPSVFVRLAGCPLRCKFCDTPYSQD-------------ANAGEKISLEKIINGIKKYS-----CDSVVITGGEPMVNHIARLCEEIKKLERHITIETNGIKFIENLCDLISISPKLSN-AYENPADSEKFLKIDPLQKLIDNYNYQLKFVI-------DKREDIVEARQLLKKLKNVLLMPQ........ 181
392 3.000e-40UniRef50_A0A1G1FS82 7-carboxy-7-deazaguanine synthase n=1 Tax=Nitrospirae bacterium GWC2_56_14 TaxID=1801696 RepID=A0A1G1FS82_9BACT  ali  22  3...............TAFVDEVFSSVQGEGPRLGERHIFVRFQGCHIRCRFCDTPAALQPKGAVCRPVSFEREAVDNPMTAQQLSELCARLVVPGRSRQVLSLTGGEPLLQRDFLSAWLPRMRPFRIYLETNGILFVVDLIDVVSMDIKLPSATGLHPFWEEHR-------KFLAACRGKECFVKAVVTGDTSEADILAFQETAMGILNDVRVIPQVHLMLQVP 246
393 3.000e-40UniRef50_A0A1Y2JLZ9 7-carboxy-7-deazaguanine synthase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=A0A1Y2JLZ9_BRAJP  ali  23  2................LPVNELFETVQGEATFTGMPSTFVRLQGCDVGCPWCDTKYTWELNHAPPDPLAIILGKIEPSPSFAAVSIDELVQTLSQSQSRHLVLTGGEPCMYDLTELSGRMIADGWTVQVETSGTEPIIDPRAWVTVSPKLMPGGMTFQAEAWQRAN---EIKMPIGKPADVEPALVWLQPLSMSKKATELCMEAARQN-RWRISVQTHKFLGV. 216
394 3.000e-40UniRef50_A0A1G3XS19 7-carboxy-7-deazaguanine synthase n=1 Tax=Thaumarchaeota archaeon RBG_16_49_8 TaxID=1802371 RepID=A0A1G3XS19_9ARCH  ali  18  1MQVSNTDTASQGRLLRLA-EEPYLSIEGEGIHIGKPMTFIRLAECNLRCKWCDTKFSWS---------------KGVEWSHKAILDRVKKLS-----CVNVSITGGEPLLQAAELQILLDQLVSRITYLNTSGTVPVFDKVDWINCDLKMPSSQMKSDLTVAHRLPEKLQFKIVVSKEIPLSIPITIQPEYNSAVDLSEWVKTHLQNHINIRVLPQLHRLIW.. 224
395 3.000e-40UniRef50_A0A0S8GS76 7-carboxy-7-deazaguanine synthase n=2 Tax=Planctomycetes TaxID=203682 RepID=A0A0S8GS76_9BACT  ali  21  1................MNVSEIFLSIQGEGRTAGVVSVFVRLAGCDLRCAWCDTEYALD-------------IKPAQSLTVEEIINRVETYPSRQ-----VVVTGGEPLIAPELPLLQELKKRDKYITLETNATRYHPIVCDLVNISPKLANSTPRQGTHEKNRLNIEAIKSFIINYDYQLKFVV-------ESERDLSEIDAILKELPRVMLMPQ........ 188
396 3.000e-40UniRef50_A0A2E6HWE2 7-carboxy-7-deazaguanine synthase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E6HWE2_9BACT  ali  29  76....PDKMPVRGDGNTLQINEIFYSIEGEGARVGQPTTFVRLAKCNLACFFCDT-----------------EFDSYSDMSVTEIVEAAKA-----HPAEWVSLTGGEPLGQDLRPLCRALGDAGYRLHIETNGTKPLFELIEYWTVSPK-----RRRVIEGFVRI---DELKYIVEDQVQPDIAKVILQPESSKPEFIQKTLGILTRHPDWRLSCRIHKMLKLP 275
397 3.000e-40UniRef50_UPI0009F8EB37 7-carboxy-7-deazaguanine synthase QueE n=1 Tax=Saccharomonospora sp. CUA-673 TaxID=1904969 RepID=UPI0009F8EB37  ali  27  98.GAATVTTPRPSVARPLLVSECFPTVQGEGPSAGKPAVFIRLSRCNLSCPGCDTPYTWDWSRFD-------PRRESRRMSVDDL-----YRWVTTQLVDLVVISGGEPLLQQLRPLVRSLAEAGHRIEIETNGTVDIIDSVDQFNVSPKTS-AFAGTAVEWDARINPEALRVFTSSKKSIFKFVVTVMPEGTTREQVLDRMSWLAEEAVRWNLSTRLHILLW.. 335
398 3.000e-40UniRef50_W6EGQ6 7-carboxy-7-deazaguanine synthase n=7 Tax=Campylobacterales TaxID=213849 RepID=W6EGQ6_SULMU  ali  26  2................LKIVEIFYSIQGEGTQVGVPSIFIRLHGCNLACSFCD---------------ELLHKGEYASLSFDEVLERIK-----VYPSMHVIITGGEPTIYNLNGFIEYLQAYMYSVAVETNGYNFNISNANWVTYSPKNWDLIEKYGYDEVKFVVSKESEKILAFKS--YKPIFIQPQNETDNKENVNFCVEFVKAHPQFILSVQLHKFLGV. 191
399 3.000e-40UniRef50_A0A1W9RK24 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Omnitrophica bacterium 4484_70.2 TaxID=1970783 RepID=A0A1W9RK24_9BACT  ali  23  1..............MKAKISEIFYSIQGEGLYVGRPMVFVRFWGCNISCKFCDT-----------------HFKDFKMLSVENVTKRIDRYK---KFTRYISLTGGEPLLWIDFLFLPILKRKRFIIYLETNGLLFVLRYLDIISMDIKLPSSTQLRPFWKEHSEFAKKFFKTVICKDTVFKFRTPLVLQPDSVKKTLSFLNFLKENRIDAYFIPQIHKFLNM. 222
400 3.000e-40UniRef50_A0A1V5SGZ0 7-carboxy-7-deazaguanine synthase n=3 Tax=unclassified Candidatus Omnitrophica TaxID=1047005 RepID=A0A1V5SGZ0_9BACT  ali  22  6......AMPDFSEEKGALISEIFSSIQGEGLRMGERHLFIRFASCNVRCEYCD-----------------EAEKPSRIMTVEEVFDEVIRLDQREGPHRFIALTGGEPLLEPEFLLIAKLKSKQCRVLLETNGIEEILESCDSVSMDMKLASVGGHRDYFEEHGRFLAASVKIVVSKDVDLEIPVVWQEGFGDGEFLAGLIDRARQRLKDVRLGFQLHKLLHI. 237
401 3.000e-40UniRef50_A0A1G1JKX7 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Candidatus Omnitrophica TaxID=1047005 RepID=A0A1G1JKX7_9BACT  ali  21  13..................ISEIFSSLQGEGPYLGVKQIFVRFGRCNMHCGYCD-------------ELERMKEGAFTVYPLEKLLGEVDGLELERGPHQAVSLTGGEPLFYTKFLFLPKLKEKGFTTYLETNGTLPVIKWCDIIAMDMKPASSTGDRPFEKEH----EAFLKTAIQKDVFVKVVVTPETKVDQMQRIVQIVKNINPKIPDVRVIPQMHKIWGV. 240
402 3.000e-40UniRef50_A0A1W1YZF0 Pyruvate formate lyase activating enzyme n=5 Tax=Clostridiales TaxID=186802 RepID=A0A1W1YZF0_9FIRM  ali  18  1..............MKIHGLQKMTLLD----FPGRVACTVFFGGCDMRCPYCHNAELLD----------------GTAPAVMDDTELLAFLKKRQGLLDGVCFTGGEPLLQKDLPFAAKVRDLGYPVKLDTNGNHPDEGLVQYVAMDIKNSPERYAEGLRQMDLAPIRESVSLLMEGKTDYEFRTTVVAELHD-DESFEQIGQWIKGAKRYYLQ.......... 189
403 4.000e-40UniRef50_A5GPM3 7-carboxy-7-deazaguanine synthase n=11 Tax=Bacteria TaxID=2 RepID=A5GPM3_SYNPW  ali  27  10...............SLPVVETFHSLQGEGLHAGRSAFFIRLAGCSVGCSWCDTKHSWPAESHPAR-------------TLHSIATE--AAAAASDGAAFVVITGGEPLHHNLDALAQLRKICGLPLHLETSGVDPLSGNPDWITLSPKHAPPRAE-------LLSRCHELKVVVHEPADLLFAEVLLQPGWESVEGQQLALDAARRDGRWRLSLQSHKWLGV. 207
404 4.000e-40UniRef50_A0A0L6Z5J9 Pyruvate formate-lyase-activating enzyme n=7 Tax=Firmicutes TaxID=1239 RepID=A0A0L6Z5J9_9CLOT  ali  15  9...................FESMGLVDGPGIRN-----VIFLQGCPLRCLFCHNPDTWN-------------FNEGTETTPEELMEKILRFKPYFKNGGGVTFSGGEPLMQPDFLLLKLCKEHNIHTAIDTSGYDEILSFTDLVILDIKHVNENDFLSLTGVSMKRLNKFIEAINNSNARVLIRHVVVPGITDSKDHLENLKNIIKTIHNVYHTLGVHKY.... 205
405 4.000e-40UniRef50_A0A0V8J9G3 7-carboxy-7-deazaguanine synthase n=13 Tax=Bacillales TaxID=1385 RepID=A0A0V8J9G3_9BACI  ali  22  17...............KLPMVEIFETIEGEGMAAGFPTIFVRVFHCNLRCTWCDTPYSYAP------------AKPEFEATIEEIIERINTFASKR-----ICFTGGEPLIHREKSAALLKAMAGIEIHVETNGAIPVLSSKVRFVMDYKLPASGEMDRMENFVVLKPHDEIKFVIGTDEDFDIASSVFSPVWETMPPEKLVNKVLSARSDVKVSMQLHKIIWDP 238
406 4.000e-40UniRef50_W6RFT0 7-carboxy-7-deazaguanine synthase n=440 Tax=cellular organisms TaxID=131567 RepID=W6RFT0_9RHIZ  ali  21  1........MSGARETQIRVSEIFPTIQGEGILIGLPTVFVRTGGCDYRCSWCDSLHAVDSAYREQWL----------PMTVDGIWAEVTRLSGGKPL--MVSLSGGNPAIQPLGGLIAHGHERGYRFALETQGSVEWFADLDVLVLSPKPPSSGMATDFDAFENDGPEIALKIVVFDDRDYAYAVYLQPGNHTPDRMLWLVDKVTEDRFEARVLPQLHVLLW.. 239
407 5.000e-40UniRef50_A0A1B1Z701 7-carboxy-7-deazaguanine synthase n=13 Tax=Bacillales TaxID=1385 RepID=A0A1B1Z701_9BACI  ali  23  16...............KLPMVEIFETVEGEGLQAGYPTVFVRVFHCNLRCTWCDTTYSYAP------------AKPEFEASIDEIISTIKSFRSSR-----ICFTGGEPLIHRELLMAMADLEHIVDIHIETNGAIDLVPFEKLFVMDYKLPASGEMDKMNNFKELQNQDEIKFVIGSEEDFEITQQVVSPVWESMPPRRLVELLLESHPNAKLSLQLHKVIWHP 237
408 5.000e-40UniRef50_A0A212JFF1 Pyruvate formate-lyase-activating enzyme n=3 Tax=Bacteria TaxID=2 RepID=A0A212JFF1_9BACT  ali  18  1..............MKGHIHETFGTKDGPGIR------FVFFQGCPLRCLYCHNPDTWKPN------------EGKYELTPQQALDEVMKVKAFVK--GGVTVSGGEPMLQPEFELFKLCKAANIHTAIDTSGFLEILTYTDLVLLDIKHINPDKYKELTARPLEPTLNFIEYLAEINKPVWLRYVLVPHFTDNEKDLHQWAQYVSQFKNVRVQMGIHKW.... 204
409 5.000e-40UniRef50_A0A174KTQ4 Pyruvate formate-lyase-activating enzyme n=76 Tax=Bacteria TaxID=2 RepID=A0A174KTQ4_9BACT  ali  16  2..............IKGKIHESFGTVDGPGIR-----FVVFMQGCPLRCLYCHNPDTWNPKG-----------KVKYQMTPGELLTEVLRYKSFI-ARGGVTVTGGEPLLQPEFEFFRLCQEQGLHTALDTSGFVEVLDYADLVLLDIKTLNPDLHPLLAGVKQDNTLLFLDELERRGIDTWIRHVIVPGYTDNDEWLEALARYVSSYKVVR............ 192
410 6.000e-40UniRef50_A0A171DJ25 7-carboxy-7-deazaguanine synthase n=10 Tax=Actinobacteria TaxID=201174 RepID=A0A171DJ25_9ACTN  ali  27  5.....MTAPGTMGRQTLLVAERFPTLQGEGPSSGVPAVFVRLSRCNLSCGYCDTPFTWDTSRFD-------LRAETTRMTVDDVTAWALD-----SGVGLVVITGGEPLLQQLVPLVGTLTGAGRRVEIETNGTVLPHPRLLVDGVGFNVSPKLTNAHLPEGKRIIAEALEVLAASGRAVFKFVVWVMPEGTTGEQVITRARLLVEEARGWSLSLRTHVVLW.. 235
411 7.000e-40UniRef50_A0A2G4EVJ0 Pyruvate formate-lyase-activating enzyme n=21 Tax=Bacteria TaxID=2 RepID=A0A2G4EVJ0_9CYAN  ali  20  5................GRIHETFGTVDGPGIR-----FIVFTQGCPLRCLYCHNPD-------------CRNAHDGKEVTVDYLINEIKKCKSYLRK-GGVTVSGGEPLMQPEFEIFDRCHQLGLHTALDTSGYCPVLEMTDLVLLDIKSYIPELYYKVTNVSIEPTLAMAKYLSEIDKPTWIRFVLVPHLTDNIENVEKLADFIATLKNVRLVLPFHKM.... 201
412 8.000e-40UniRef50_A0A1V5T3B8 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A1V5T3B8_9BACT  ali  22  1........MRESNSHTASLVEIFSSLQGEGAYVGRKMTFVRFGSCNLKCRFCDTPQGMCTRDHCLIEKVPGSAKFDKPVSAAQLCEMMSRF-----DDSILSITGGEPLKQAAFLEQWLPQRPNRTILLETNGVLHLLPNIDIISMDFKLPSSTGEKEFWEEHSIFLQNSVA--SGKEIYIKIVVTPETTDHDIEKVIRIITSINKYIPDVRVQPQMHKHWGI. 250
413 8.000e-40UniRef50_A0A1J4VNP5 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Omnitrophica bacterium CG1_02_49_10 TaxID=1805289 RepID=A0A1J4VNP5_9BACT  ali  23  1..............MTAPVSDIFISIQGEGVFVGEKQTFVRFYGCNLTCSFCDTK----------LYTWQDTG-------VDELRGRIRSL-NGSDPAKYISLTGGEPLLHAGFLAIPVMRDDGYKIYLETNGTLKVIDLMDVVAMDIKLPSSCGLPDMW-------DDHKKFIARAKDKFVFVKAVITDVTLDDRLKRLKDMAAGSLSDVRIVPQMHKLAGI. 226
414 8.000e-40UniRef50_E0SSE2 7-carboxy-7-deazaguanine synthase n=1 Tax=Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1) TaxID=583356 RepID=E0SSE2_IGN  ali  25  3.............GLNMRVSEIFYSIQGEGPFIGRPAVFIRLQGCNLRC----TKNSVGWD-CDTQYAWDSS--GGMEISIDRVVDIV-----RQYQCRHIVITGGEPMIQQREVIELIKRLDGYAIEIETNGTIPLDPDFPVEKVRLNVSPKPHAPIRPE--YIRYASCLKFVVASEKDLVFRIWLMPASRNVDENIRLCWEYAK-LRGYNVTPRLHIL.... 210
415 8.000e-40UniRef50_A0A1V5M013 Pyruvate formate-lyase 1-activating enzyme n=4 Tax=Bacteria TaxID=2 RepID=A0A1V5M013_9FIRM  ali  17  14...............................YPGKICAVIFTPGCNMDCFYCHNRALVDSD----------------DQSITTVEEVLSFLERRKGFLEGVVVSGGEPTLQKLLPFLLEIKRLGYSIKLDTNGTNPEKGLVDYIAMDFKAPYEKYSEICTKVDIGQIKKSVKLLMNSGVDYEFRTTLAPGL-DTKDIMEIGMEI.................... 178
416 8.000e-40UniRef50_A0A2N2EY69 7-carboxy-7-deazaguanine synthase n=1 Tax=Elusimicrobia bacterium HGW-Elusimicrobia-1 TaxID=2013763 RepID=A0A2N2EY69_9BACT  ali  27  8.GATAVSPRSKNPDITAPVNEVFFSFQGEGLRAGEPQIFVRFAGCNLRCRYCDTPSARHLS-------------AGKKTAVAALVRKIAKISSARPRPRTISLTGGEPLLYPDFALIGELRKRKFRVSLETNASLPLVRLADYISADVKPPSAAGKDLFAVYAKAFPAASVKLVLDDKTRLKFALTLQPATPSAPANLFRFVRSAESILGVRIIPQLHKLLW.. 251
417 9.000e-40UniRef50_A0A1C6HFW3 Pyruvate formate-lyase 1-activating enzyme n=11 Tax=Firmicutes TaxID=1239 RepID=A0A1C6HFW3_9FIRM  ali  18  14...............................YPGKLAATVFTGGCNLRCPFCHNALLVTRLA---------------ETPEIPEQEVLDFLASRRGLLDGVVLTGGEPLLQPDADFLRKVRELGFAVKLDTNGCDPARGLVDYVAMDVKNAPARYAEGIPGFNPAPVEESIRLLRKSTVDYEFRTTLVRELHRPEDLDAIAAW-LAGAPRYYLQ.......... 190
418 9.000e-40UniRef50_A0A1C5EKB4 7-carboxy-7-deazaguanine synthase n=2 Tax=Streptomyces sp. MnatMP-M17 TaxID=1839780 RepID=A0A1C5EKB4_9ACTN  ali  22  2................LKISQLFPTVQGEGSAAGRHCLFVRVFDCNLECTFCDTAYTWAVTDEKHRYDRDDPAYGLKLMEPDDVLSGLRKLWDIKTRPTIIVVSGGEPMMQALVPVLQQLRDWGNEVHIETAGTIPPTASFDSVVTQYNVSPKLANSGNRLSKRYKPSVLAALLDTGKAWFKFVVT-----GDHEKDLAEVDRIVADVPRVMVMP......... 209
419 9.000e-40UniRef50_A0A2G3PWP3 Glycyl-radical activating family protein n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=A0A2G3PWP3_9FIRM  ali  13  5.............KVKGRIFDIYSVHDGPGIRT-----VVFLKGCFLRCKWCCNPESQNFNSEVMKVAGKDKV-IGRDVTVEEVLEAVLRDRSYFKSGGGVTLSGGEVLFQPDFALLKTFKENGLHTAIESSSFERLLPYLDLYLMDIKHMDSAKHKAYTSQPNERILENAKHIAASGTSLIIRVPVIPGFNDTEEEIKAIASFTESLEEIHLLP-YHRL.... 218
420 9.000e-40UniRef50_A0A0G3XK98 7-carboxy-7-deazaguanine synthase n=2 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A0G3XK98_9SPHN  ali  21  14....................EIFASLQGEGASIGRPVAFVRLSRCNLACTWCDTAYTWHFEGDNRPHRDGVTFDRKANQVVLDEADVAKRIAALGQN--RLVITGGEPMLQAAALAKMLDHLPDIEVEIETNGTVKPPARLDVRVDQFNVSPKLAHSGNSATQALIPDMLDFWADDPRAFLKFV---IAEPADLAEAMGLVDRHRHPKDRVYLMP......... 203
421 1.000e-39UniRef50_D1BNB6 7-carboxy-7-deazaguanine synthase n=19 Tax=root TaxID=1 RepID=D1BNB6_VEIPT  ali  20  1................MNVIEIFASIDGEGSRQGLLTTFLRLHDCNIRCSYCDTTYSYGIDSVFTEMTAAETITGGEPLLQEAAVVELIDELNRRKAETMQDNTSGQAGSTCIIDIDKFDKREMYDFNIETNGTIIPSFHRDWFTYDYKTPSSLAEESMDIFKVATERDLIKFVVGSPEDLDCMRRIIEQYPTVAQIPASIIDYMKAYNNVRFQLQIHKFVWDP 242
422 1.000e-39UniRef50_D9QQX8 7-carboxy-7-deazaguanine synthase n=12 Tax=Firmicutes TaxID=1239 RepID=D9QQX8_ACEAZ  ali  24  4............EGVKLPVVEIFNSISGEGISAGEIVTFVRVAGCNLRCDYCDTMYSY-------------QDEEYELLTPQQIVNRINNF-----GTQQVICTGGEPLEEPKRYLPLYLAKQGFEVRIETNGSWSVYNQQELYTLDIKCPSSNMYNLFTNLEQLGLNDEIKFVVQDKSDIDYALKVIDDYKNEKKLVSILQEFAQFNLKVRLSIQLHKLIWDP 235
423 1.000e-39UniRef50_D0GLP1 Pyruvate formate-lyase-activating enzyme n=159 Tax=Bacteria TaxID=2 RepID=D0GLP1_9FUSO  ali  15  1..............MEGYIHESFGTKDGPGIR-----FVLFMQGCPLRCLYCHNVDTWNVK------------DKKFMMTPEEVMKEILKVKGFI-RTGGVTVSGGEPLLQPEFILFKLCKENDIHTAVDTSGYMEVLKWTDLVLLDIKHINPNKYKKLTSVSLEHTLEFAKYLSEINKNAWIRYVLVPGYSDDEEDLHEWAKFVSQFKNVRVILPFH...... 198
424 1.000e-39UniRef50_A0A0B3VKU8 Pyruvate formate-lyase-activating enzyme n=25 Tax=Bacteria TaxID=2 RepID=A0A0B3VKU8_9FIRM  ali  16  3...............TGRIHETFGTVDGPGIRS-----ILFFQGCPLRCKYCHNRDTWN-------------VKDGTEYTAEELIDNVSRYSSYWRSGGGITASGGEATLQADFELFAIAKERDIHTCLDTSGFVDILDNTDLVLLDIKHMNEEEAKNLTGVGIEKTLKLARHLDERNIPIWLRHVLVPGITDSEENLSQIGELAASLNNIRLILPYH...... 200
425 1.000e-39UniRef50_A0A1J1LPL3 Pyruvate formate-lyase-activating enzyme n=5 Tax=Bacteria TaxID=2 RepID=A0A1J1LPL3_9CYAN  ali  18  9..PETIQSISRLSKVSGRIHETCGTVDGPGIR-----FIIFTQGCCLQCLYCHNPDTRN-------------REDGIEITVDELIAEIQKYRSYRFSGGGVTISGGEPLVQPDFAIFQRCQEIGIHTALDTSGFVPVLEFVDLVLLDIKSFDPLTYRQVTGTSIEPTLRFAHYLNEIKKPTWIRFVLVPNLTDDPDNIEGLAKFISQLKNVELSP-FHKL.... 221
426 1.000e-39UniRef50_A0A2R4N0C0 7-carboxy-7-deazaguanine synthase n=4 Tax=Carboxydocella TaxID=178898 RepID=A0A2R4N0C0_9FIRM  ali  24  6..................LIEMMSSFQGEGTVVGLRQLFLRFAGCNLACAYCDTRYSLHAQETWKVEFPPGTNILTNPVTVEQLLEQIKKFNPDKH--HSLSLTGGEPLLHSDFEFLPKIKQMGWKIYLETNGTLQVLDYIDIIAMDIKLSATGAPTPWEEHQKFLELAFIKVVVNSRTDIDIVLQPQTGSELPPAN-RWIEWILKPFYRVRIIPQTHKILGV. 243
427 1.000e-39UniRef50_A0A2D7DMS8 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteria TaxID=2 RepID=A0A2D7DMS8_9SPIO  ali  25  26.......ARSMETDPQGNLVEVFWSAQGEGTFVGRPTVFVRFGGCDLRCRWCDSAYTWHPESCRXEMEPGNQSFASEANPIRRILEAIQQLEPQ--PGSFISLTGGEPLLQPEFALAQACQERGWQTHLETHGLDPVLPSIDLVAMDWKVKPAASASVTQEDFYRLHREFMALAXQARVNVKVVLTSQTSADDAALILQPVSEIGSSRPDVRLIPQTHKVYG.. 285
428 1.000e-39UniRef50_A0A285NCH6 Pyruvate formate lyase activating enzyme n=25 Tax=cellular organisms TaxID=131567 RepID=A0A285NCH6_9AQUI  ali  17  1..............MKIGGFQKFSLID----YPGKISAVIFVQGCNFRCHYCHNRDLVLPE------------YFSKTIPEEEI---IDFLSLRKGKLQGVVITGGEPTIFPDLPFIYKIKKMGFYIKLDTNGSNPDMKLVDFVAMDIKAPVEKYGEITGAVDKNKIIQSIDILKNSGVHYEFRTTVVKGLISEIDLYRIA-NLIKGAVRYAVQ.......... 189
429 1.000e-39UniRef50_S6CFF3 7-carboxy-7-deazaguanine synthase n=4 Tax=Coriobacteriia TaxID=84998 RepID=S6CFF3_9ACTN  ali  24  18...ARHTIAPRAQL--FPVAEKFVSVNGEGLAAGRPAAFIRFAGCNMWCTYCDTRWANHPLVEV------------EGWSVPDLVAWVAE-----TGVSCVTLTGGEPLLQPYLPLLAVDDPRPLRVEIETNGSRDLSPMAHLFTVDWKTPTAGAAMRRENYDLLDTRDAVKFVVGTEDDLVFMSVLASPVWGAIESAEIAAYLIEHGLDARLQLQLHKIIW.. 254
430 1.000e-39UniRef50_A0A1V5Y0C1 7-carboxy-7-deazaguanine synthase n=1 Tax=candidate division BRC1 bacterium ADurb.Bin183 TaxID=1852823 RepID=A0A1V5Y0C1_9BACT  ali  19  2................LNVSEMYPAILGESTWAGQPCTIIRLGGCNLNCVWCDTKFAQL---------------DFSAMSPMQI-----YSYCRKTGLDTVLVTGGEPLAQKETPRLLQNLVKKYRVILETNGTFSLKNVSVIVVLDVKCPSSGMAEHWENLELLKEFDEVKFGISHLQDFNYALDVVKKFDLHNRVADLSAWILKTRLPIRLNIQWHKYIWSP 206
431 1.000e-39UniRef50_C1CXM5 7-carboxy-7-deazaguanine synthase n=19 Tax=Bacteria TaxID=2 RepID=C1CXM5_DEIDV  ali  31  1..............MKYPVFERFYTWQGEGVHLGRAAYFVRLYGCPQECPWCDSAGTWHKDYRP---------AGVQLMTPEAIAACVAQESPEGAV---VVITGGEPILFDLTPLVEALHGLGRRVHLETSGIAPLRGAIDWVTLSPKLPLPSVVQQAHEVKIIVIRDGLATLDGLKDDA--VIWLHPEWSKAREVLNAITEAVKANPRLRAGYQMHKL.... 205
432 2.000e-39UniRef50_A0A2N1U554 7-carboxy-7-deazaguanine synthase n=3 Tax=Planctomycetes TaxID=203682 RepID=A0A2N1U554_9BACT  ali  25  6................IQISEIFYSIQGEGLLAGRPSVFVRLAGCPLRCKFCDTKYANDS-------------KAGEIRTIDEIVKQIKKYKT-----DYIVITGGEPMICPNLPLLCNALKK-YHITIETAGIKFIDGLKCLMSISPKLSN-AYLKKSDKKLYLKIDRLKKLIKNYNYQLKFVIEKAGDIKEVEKVLKELKN--TDRSKILLMPQ........ 184
433 2.000e-39UniRef50_UPI000A03FC4B anaerobic ribonucleoside-triphosphate reductase activating protein n=1 Tax=Erysipelotrichaceae bacterium NK3D112 TaxID=877415  ali  14  161...............................YPGKAACTIFLSGCNFKCPFCHNRDLVFIPERYEYF---------------DVNDIMEYLEKRKGILDGVAISGGEPLLQENLHLIERIRELGYQVKLDTNGAYPEKGLVDYVAMDIKNSPDKYARTLESFSLDPIRESVEFLKSSQIEHEFRTTVVRELHTAEDLLE-IGRWLGENETYYLQ.......... 339
434 2.000e-39UniRef50_A0A285NQF2 7-carboxy-7-deazaguanine synthase n=1 Tax=Hydrogenobacter hydrogenophilus TaxID=35835 RepID=A0A285NQF2_9AQUI  ali  21  5.........KVRTSTTLSINEIYPTIQGEGLLVGSPCLMVRFQGCNIRCPWCDQPSALVFKRPNTDLST--------------LLEEIKR-----HPHKHIVLTGGEPLAQPNLHLLVYELQEGYFVQIETNGTLWNENLVVEDRIHITCSPKWTANWYVHPSVLKNAKELKFVVDDNEFLPFLVVLQPEGNKEKKALKIQTDLLEEGYTVRVLPQLHKLIGL. 217
435 2.000e-39UniRef50_A0A1A7BFP1 7-carboxy-7-deazaguanine synthase n=19 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A1A7BFP1_9SPHN  ali  23  13...................SEIFASLQGEGPSMGVPVAFVRLSRCNLACTWCDTAYTWRFEGDNRPHIAYDRKANQVTLSPQETAARIAALGQNR-----LVITGGEPLLQAGALAEMLAHLPDMAVEIETNGTVAPPARLDIRVDQYNVSPKLAHSGNPAELALIPERLDAWATDPRAFLKFVIAAPE---DVDEVVALHRRYRFRPERVFLM.......... 202
436 2.000e-39UniRef50_A0A0U3F5I7 7-carboxy-7-deazaguanine synthase n=1 Tax=Ignicoccus islandicus DSM 13165 TaxID=940295 RepID=A0A0U3F5I7_9CREN  ali  23  1.......MEPKGNFMIF-IIEKFVSVQGEGLNVGTPALFIRLAQCNLRCPWCDTKYSW---------------RKGTPISIEDLVNYVLDE-----NLPLVVLTGGEPLIYSIAEFLRRLRERGYKVQIETNGTIPLRGFDNYVSISPKVTCVYKVYFVNLIKRIINNYNIKIVV-SNDDIKCLRQFIDELGDVEDSKAIVEEILSDRRKVRVIPQLHKLIGI. 225
437 2.000e-39UniRef50_Q9K0Q5 7-carboxy-7-deazaguanine synthase n=218 Tax=Proteobacteria TaxID=1224 RepID=QUEE_NEIMB  ali  27  7..........APENPQYRIVEIFESLQGEGWNTGMPAVFVRLGKCNLACGWCDTDYLTFG-----------------MMGLSDILGRLKTYAARN-----IIITGGEPTIQPLDMLLDTLKAEGYFLCLETNGLNPAPPQIDYVATSPKACYAAKYENADEVRIVADGDVLAFCMERKIRAHHYYLSPCEQDGAMNIYDTIRQILNSRPDWQLSVQTHKWAGI. 211
438 2.000e-39UniRef50_A0A286ED90 7-carboxy-7-deazaguanine synthase n=1 Tax=Alysiella filiformis DSM 16848 TaxID=1120981 RepID=A0A286ED90_9NEIS  ali  29  2............SEPTYRIVEIFETLQGEGYNTGMPSVFIRFGKCNLACHWCDTNY-----------------NEFGFMSLSQIMQKV-----HQFAARNIIITGGEPTIQPIEILLNQLKSESYFIAIETNGLKDVPAQIDYVA----TSPKRLYAQAYEKRCLKRADEVRIVVDGDDVFDFYYLSPCEHHGEMNVLQTIALLGKLNPHWQLSIQTHKLCGI. 204
439 2.000e-39UniRef50_A0A2N6FAC0 7-carboxy-7-deazaguanine synthase n=1 Tax=Desulfuromonas sp. TaxID=892 RepID=A0A2N6FAC0_9DELT  ali  21  4.SGSRRTPVPATAKASANLVEVFSSCQGEGPLVGCRQVFVRFSGCNLDCRYCDTPWSALPACRETEPGSGHYRSVHNPVTLESLLSTLVGWQRQAPGLHHISLTGGEPLYHTDVLSWLPELSRVMPLYLETNGTLPLIGHLAWVSADIKLPSLTGHTPFWDEHR----AFLKICAGAGN---CRTVVVCEPNTPEDELLLAASMVAEHPDVRIIPQVHTLVDIP 263
440 2.000e-39UniRef50_A0A2E0CEE3 7-carboxy-7-deazaguanine synthase n=3 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E0CEE3_9BACT  ali  20  3...............KLKVNEIYYSIXGESSLSGLPXIFIRLTYCNLRCTYCDSEYA---------------FYDGEDLTVKEILKKIKKYDXN-----LVEVTGGEPLLQKECLNLLTELENNYNVMXETSGSLPIISKNVKKIVDXKCPSSGMKNLWSIIDDISNNDEIKFVIGNQDDFKWALKKIEKYXIENKCEILVKWMXNSNVNARFQLQMHKHIWD. 208
441 2.000e-39UniRef50_D3SXF4 7-carboxy-7-deazaguanine synthase n=15 Tax=Halobacteria TaxID=183963 RepID=D3SXF4_NATMM  ali  22  11.TPADTDAESAVDG--LPINELFYSLQGEGVLAGVPSVFVRTSGCNLRCWFCDSYHTSWEPTHA-------------WMELDAILDEIE-----SHDADHVVLTGGEPLLHDAVALLEALDERGYHTTVETNGTIYRDAPIDLASISPKLASSGEWEDRHEANRIDMAALAALVEEYGFQLKFVVTDADDMPEILDLLADLREAAIRDDDVLLMP......... 239
442 2.000e-39UniRef50_A0A1G1KRH5 7-carboxy-7-deazaguanine synthase n=5 Tax=unclassified Candidatus Omnitrophica TaxID=1047005 RepID=A0A1G1KRH5_9BACT  ali  22  2..............MTAKISEIFQSIQGEGKYAGVRQVFVRFFSCNMRCVWCDTPVSM-----------GEGNSNYQELDLQDVFSRVSALW---KNCHSVSLTGGEPLVQTHFILLPLMKRAGMPVFLETNGILYIVDDVDIIAMDIKLPSSTQDRAYWQEQ----EEFLKMAVAKDV---FIKIVVSTRALKADILKAVDLVAGVSRDIPVIIQ........ 189
443 2.000e-39UniRef50_F6IMW3 7-carboxy-7-deazaguanine synthase n=122 Tax=root TaxID=1 RepID=F6IMW3_9SPHN  ali  22  14....................EIFASLQGEGASMGRPSTFVRLSRCNLACQWCDTAYTWRFEGDNRPHRDDTAFKTANQLSLAEVAAQVAAL-----PPDRLVITGGEPLLQARMIGELNALRPGMHVEIETNGSVAPHAALDPLIHQFNVSPKLAHSGNPADLALIPQRLAAWSADPRGYFKFV---IAEPEDLDEVLALQQTYAIPGERIFLMP......... 207
444 2.000e-39UniRef50_A0A2H0AA79 7-carboxy-7-deazaguanine synthase n=5 Tax=Candidatus Desantisbacteria TaxID=1819803 RepID=A0A2H0AA79_9BACT  ali  24  3.............EPKGNIVEIFKSIQGEGLWIGEGQIFLRLAGCNLSCKNCDTNYALEIPQ---KYKIEDNDYRNNPVTLTETIETI---KSYGLFSTTVSVTGGEPLLQIDKMLLPILKSEGCKIYIETNATLPILPWIDIVSADIKLPSFTGEEDIPKEHR----EFLRIAKEKDLFVKVVVTVIQPAMKNGKLMENQERLAKRLTTVRLIPQIHKLIG.. 239
445 2.000e-39UniRef50_A0A254RCQ2 Pyruvate formate-lyase-activating enzyme n=4 Tax=Bacteria TaxID=2 RepID=A0A254RCQ2_9BACT  ali  16  10....................ETFGSVDGPGVR-----FVVFLQGCPMRCKFCHNPETWSFDIAGRDSGSNVRATLPNENPFEDLLKKALRYKSYWGAEGGITVSGGEPLAQLDFEFFELAKAAGVHTCIDTSGIERLMKVTDLLLVDIKHIDNVVHKELTGHGNENILEFFRYLDEIHKPIWIRHVLVPGISDDDNALKRTRAFIDTLSNVRVVLPYH...... 222
446 2.000e-39UniRef50_D2R4S1 7-carboxy-7-deazaguanine synthase n=16 Tax=Bacteria TaxID=2 RepID=D2R4S1_PIRSD  ali  25  1................MLIAELYTSLQGEGRLTGTPSVFVRASGCNLRCWFCDTPFTSWQP-------------EGEDWSLEEIVHQVQA-----KQTSHVVITGGEPMLYSEVPLTQELKRLGLHITIETAGTLHLEVACDLMSISPKLASSTPSAARHERVRHQPHVIRKMIAEYDYQLKFVI-------DSESDFAELDSWLEEFPEVRLMPQ........ 188
447 2.000e-39UniRef50_A0A285NKR4 7-carboxy-7-deazaguanine synthase n=1 Tax=Persephonella hydrogeniphila TaxID=198703 RepID=A0A285NKR4_9AQUI  ali  29  3...............SIKIVEIFRTVEGEGKWVGLPVSFIRLEGCNLRCPWCDTSYSYDG-------------KTFEEISIDSVIKEIEKL-----GLKRVCITGGEPFLTPQLPLVKKLINRGYKVLIETNGTLWIKELEDYITCSPKPPAPELLPFITELKYLKIEDIIKTLRIIKNDF---VVLQPESNRPEKALKLQEEILKTGYESRIIPQCHKILGLP 211
448 2.000e-39UniRef50_A0A2X0VB75 Pyruvate formate-lyase-activating enzyme n=3 Tax=Anaerobiospirillum thomasii TaxID=179995 RepID=A0A2X0VB75_9GAMM  ali  15  20...................FETFGSVDGPGVR-----FVVFMQGCRMRCKYCHNPDSWKMD-------------AGQQLDAQQVLDKALRYKSYWGDKGGITVSGGEPLVQMEFELFTLAQDMGIHTTLDTSGFNALMDKTSLVMLDIKHIDPKMHLELTKCPLENILDMAAYLDELKKDVWIRHVLVDGYTNDETYLRQTADFLKTLSNVREILPYHKWLGLP 229
449 2.000e-39UniRef50_Q9ZCV2 7-carboxy-7-deazaguanine synthase n=59 Tax=Alphaproteobacteria TaxID=28211 RepID=QUEE_RICPR  ali  27  22...........GDGTKLEVQSIFKTIQGEGIFVGYPSIFIRLGGCNLACNFCDT-----------------EFEDFKLIDIDQILNKVKNLSLNSKNAKTVVITGGEPMRQPIGLLCQKLLDQDFKVQIETNGTLYRLPKEVFIVCSPKV-GKTGYNKIREDLLPQISA-VKFIISKNIAYDIPVFVQSMDQNDKENNELAVKLALE-SGARLSLQTHKFLGI. 233
450 2.000e-39UniRef50_R7BRJ2 Pyruvate-formate lyase-activating enzyme n=3 Tax=Terrabacteria group TaxID=1783272 RepID=R7BRJ2_9FIRM  ali  18  1..............MILCGYEKFSMVD----FDGKIACTVFTGGCNFRCPFCHNAPLVVGNV------------KSQQIDCDEVFD---YLQKRKGLVDAVCVTGGEPTLQPDLDFLAKVRDMGYATKLDTNGLRPDKKLVDFVAMDVKNSPEKYARGVNNVDMGKILESMRLLKESGVDYEFRTTIIKEFHTADD-MQKIAYLVSGAPRYFMQ.......... 190
451 2.000e-39UniRef50_A0A1Y0HQE5 7-carboxy-7-deazaguanine synthase n=3 Tax=delta/epsilon subdivisions TaxID=68525 RepID=A0A1Y0HQE5_9PROT  ali  27  2................LKVVDIFYSIQGEGAHVGVPSIFIRLYGCNLTCSFCD---------------EFLHKGEYESLSFDEVLTRIKPY-----PAMNVIITGGEPSIYNLNGFIDYLQAYMYAVSVETNGYNFNIASANWVTYSPKDWDKIEKYGYDEIKFVVSKESAKILEFSS--YKPIFIQPQNEMDNKENVAFCVEFVKEHPQFILSVQLHKFLGV. 191
452 2.000e-39UniRef50_A0A0L6CUV7 7-carboxy-7-deazaguanine synthase n=4 Tax=Bacteria TaxID=2 RepID=A0A0L6CUV7_9RHOB  ali  22  5................IRISEIFPTIQGEGALIGEPTVFVRTGGCDYRCSWCDSLHAVNAEYRATW----------APMPPAEVMAEVAHLSGDRPL--MVTLSGGNPAIQPLGPLIEMGKAQGYRFAMETQGSVDWFASLDMLVLSPKPPSSGMTVDWPVFEDCVTAAVLKIVIFDEADYLWAHTPPPPEDDDDRMRWLVDRVVADG--WFVLPQLHVMLW.. 234
453 2.000e-39UniRef50_B2TNF4 Pyruvate formate-lyase-activating enzyme n=19 Tax=Terrabacteria group TaxID=1783272 RepID=B2TNF4_CLOBB  ali  14  3...............KGRIHETMGLVDGPGIR-----VVVFFQGCSLRCKYCHNPDTW-------------TYDGGDEYTPEELVKKIERYKTYFKSNGGVTFSGGEPLRQPEFLLLKLCKEKGIHTCLDTSGYNEILKCVDLVLFDVKHYNKEGYKNVTYMDINKSLKFLNSVQQFKIPIWIRHVVVPGLTDGEEHIRNLKKYISNIDGV............. 190
454 3.000e-39UniRef50_A0A1H9AE55 7-carboxy-7-deazaguanine synthase n=2 Tax=unclassified Lachnospiraceae TaxID=186928 RepID=A0A1H9AE55_9FIRM  ali  21  2................FKVAEKFVSINGESRRAGELAVFIRFGGCNLSCTYCDTAWAIDAPLADTGALKDGETSSSYEMSGQDIVDYIRD-----TGVDNVTLTGGEPLLQCLEDLVVDIISLNKRVEIETNGAVSIEPLFELITLDYKCPGSGMESLMDNYKYLREYDAVKFVVMNREDLDRAREVIMRYQLVEEPREIVEYMIEHGMNVTNQLQQHKFIWPP 248
455 3.000e-39UniRef50_A0A1M3MTD0 7-carboxy-7-deazaguanine synthase n=3 Tax=Myxococcales TaxID=29 RepID=A0A1M3MTD0_9DELT  ali  25  4............SRMKSGDPEIFATVQGEGTSAGVPSVFVRLADCNLRCSWCDTKYTWDWIKYDRASETI-------EIEVDEIARRV--LEASGEGVRNAVFTGGEPQQDDLVLLATRLREHGFRIEVETNGTVSPTEAFAACVDQWNVSPKLASSGNTDRARHRPLVLQWFAARPNAQLKFVIT---SDADVAEVHELVETLGVPRERVILSP......... 196
456 3.000e-39UniRef50_A0A2V6SFD7 Uncharacterized protein n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6SFD7_9BACT  ali  30  81...........SRAPAGRVAEVFYSIQGEGATAGMPAVFVRLQGCSVGCAWCDTKYSWDPE-------------AGRAVDLDALVDEAAAF-----PCRRAVVTGGEPLESSLFPLLRSLGERGFAIEVETSGILPPPRV--GRAVQWNVSVKLAGSGVAESRRIQPASIRGFLAQD-AWWKFVVT---DDADVAEVLKLAERFA--LPRARILLQ........ 260
457 3.000e-39UniRef50_UPI00085C8309 glycyl-radical enzyme activating protein n=2 Tax=Clostridiales TaxID=186802 RepID=UPI00085C8309  ali  14  9...............TGRIFDVFSVHDGPGIRT-----IIFLKGCPLRCKWCCNPESQQYEIQKMVVNGVPK-TMGRDVTVQEVLNEVRKDLTYYWSGGGVTLSGGECLFQSDFAILRACKEQCINTAIETTGFAPLLPWLDVVLMDIKHVDDEKHKAFTGQSNRLILENAKKIAESGANLVIRVPVVPEFNHTPREIYQIAKFAEQLPGVRILLPYHRL.... 220
458 3.000e-39UniRef50_A0A1D2WGI3 7-carboxy-7-deazaguanine synthase n=3 Tax=Methanosphaera TaxID=2316 RepID=A0A1D2WGI3_9EURY  ali  23  1........MKEDSSITHKIIEIFSSIQGEGLLIGKRQIFIRFAGCNINCKYCDTENS-------------KTNQLGKEYSYDQLNEEIQKL--MTPDFDSLEITGGEPLLHSD-YIHDFLKKYPYKAMLETNATKPIEDVIDIVSMDIKLPEHFNSKDEWIEVYENELKSIEVLNNQKYYIKIVVVSPMELWDKKDNLFKISEIIGKNHSVSIIPQIHKYLNV. 235
459 3.000e-39UniRef50_A0A1F2QYM6 7-carboxy-7-deazaguanine synthase n=1 Tax=Acidobacteria bacterium RBG_16_68_9 TaxID=1797173 RepID=A0A1F2QYM6_9BACT  ali  23  3...............KGYLQEVFVSFQGEGAYAGRRHLFIRMAGCNLRCRYCDTPDSLAGPHFRVYYGGRETHDAPNPVSCSGLTPHLARLMETQAPIDGVALTGGEPLLQAAFLAELLRRELPRPRLLETGGTLPVIPWIDSISMDIKIPSNTGERFWDEHTRFL------RLARGKVHVKILVDAATLVAEVERAAELVRATASEAPDVRVLPQVHKTLGV. 244
460 4.000e-39UniRef50_A0A229RBY5 7-carboxy-7-deazaguanine synthase n=2 Tax=Pseudonocardiaceae TaxID=2070 RepID=A0A229RBY5_9PSEU  ali  22  1MKPPTVPAPDRD----LVVNETFPTFQGEGPSTGRYAHFIRLFGCHLSCTWCDTPHTHDPTRYD-------LTAEQRILSIDDILSWLAAA-----PVDLLVITGGEPMLQPLERLLLAIRDRDIEIEIETSGTIPPTDLLTAAATRFNVSPKLAHSGLRRHQRIRPAVLRHLAGTGKAVWKFVVQEIDDLDEVQELTEAYDWIMPEGRRWHLSPRLHTLLW.. 236
461 4.000e-39UniRef50_A0A2E7NQ23 7-carboxy-7-deazaguanine synthase n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7NQ23_9PLAN  ali  26  1................MWIAEVFASIQGEGRFAGIPSAFVRTSGCNLRCRFCDTPETSWRPRGDHR-------------DWDAVVEEVSEL-----GCPHVVVTGGEPMLQPGVPMTRALRDRGLVVTIETAGTVDANVSADLMSVSPKLANSTPVDDVWSVRHEAARDSLKFVVDQSADVERRVWLMPQAVTSEQIAERAGWIREAAEGWRVSPRLHIELW.. 220
462 4.000e-39UniRef50_A9DMX1 7-carboxy-7-deazaguanine synthase n=13 Tax=Bacteria TaxID=2 RepID=A9DMX1_9FLAO  ali  21  14....................EIFHSIQGEGKNLGQPSVFIRTSLCNLHCIWCDTDYTWNWEKTRFAHVKDSDPLYEKYLTLEEIYNEVAK-----SGCKNIVLTGGEPMMQSALMKFFNTKATDYFFEIETNGTLLPDATFDALIDQYNVSPKLANSNNPKKLREKPEAYQYFSKNEKAVFKFV---ISSENDLTEVLEICKNYNIPKQKVYLMP......... 212
463 4.000e-39UniRef50_A0A1G1EC75 Anaerobic ribonucleoside-triphosphate reductase activating protein n=1 Tax=Nitrospinae bacterium RIFCSPLOWO2_12_FULL_45_22 TaxID=  ali  21  19...............................WPGRISSVIFLAGCNFRCPYCHNHPLVLAPA---------------RLPTIPLESILSFLGGHKDWIDGVVITGGEPTLYAALPLVQQFKERGFRVKLDTNGSNPILHLLDYVAMDIKAPLEENKYTLVEVDLSRINQSIQLLLDADIPYEFRTTVLPLFVTREDVLAIAR-VIKGGKRYVLQPQ........ 201
464 4.000e-39UniRef50_A0A0A2TUR1 7-carboxy-7-deazaguanine synthase n=182 Tax=Bacilli TaxID=91061 RepID=A0A0A2TUR1_9BACL  ali  23  42...............RIPVMEIFPTVQGEGMVIGQKTMFVRTAGCDYRCSWCDSAFTWDGSGKDLI----------RMITPEDVWNELRR--VGGSRFSHVTISGGNPLLASLGGLVKLLRENGIRTAVETQGSRPWLGDIDEVTVSPKPPSSGMNTDWAVLDDLIHRHSLKIVIFDETDLDYARRVHAQYPGTDSLLARYEWLIDDLNDVRVLPQLHTLVW.. 275
465 4.000e-39UniRef50_A0A173RKD0 Pyruvate formate-lyase-activating enzyme n=229 Tax=Bacteria TaxID=2 RepID=A0A173RKD0_9FIRM  ali  16  3...............KGYIHESFGSVDGPGVR-----YLIFTTGCAMRCQFCHNPDTWNM-------------NSGTLYTADELIDKAWKYRTYWGSKGGITVSGGEPLLQIDFELFQKAKERGINTTLDTCGFQELMKVTDLVMLDIKHIDDEQHKILTGQTNKNILDMARYLSDTGKPVWIRHVLVPERSDKDEYLHRLHDFIETLDNVVEVLPYHKELGIP 218
466 4.000e-39UniRef50_A0A0S8GLR2 7-carboxy-7-deazaguanine synthase n=2 Tax=candidate division WOR-3 TaxID=1703755 RepID=A0A0S8GLR2_9BACT  ali  21  17...............KGYVRELFTSIQGEGIYAGTRQTFVRFLGCNRACNYCDTPDARIRTGAFEYNGQQFDNPVAAEFIVPRITE------------RAVSITGGEPLTQPDFLLEKDCKALGKDVYLETNGTVPVIDYIDTIAIDFKIESATGEKTPWDAHAQQKNVFVKITINQNVAVDKRIPLVIQLKPIKPYVDMQKQALGWLPDVRIIPQIHKYLGL. 241
467 4.000e-39UniRef50_A0A2D5AQS8 7-carboxy-7-deazaguanine synthase n=3 Tax=Verrucomicrobiae TaxID=203494 RepID=A0A2D5AQS8_9BACT  ali  22  12....................EIFYTLQGEGRFTGRPSVFIRASLCNLSCNWCDTAYTWNWDNTNFEHESKTKFKREDQITTDEIIDVVNQYSCRNY-----VFTGGEPLLQVELMDALIDKDEKCHFEIETNGTLFPDDDFLARVHQLNVSPKLANSDVPQERRFKQTVISQLAATGKADFKFV---IGDTVDFDEVKCLIDTCHLPAGNIFLMP......... 205
468 5.000e-39UniRef50_Q2G4E0 7-carboxy-7-deazaguanine synthase n=33 Tax=Sphingomonadales TaxID=204457 RepID=Q2G4E0_NOVAD  ali  21  13....................EVFSSLQGEGPGMGRPSVFVRLSRCNLACRWCDTAYTWRFNRPHRDEVAFEKAGNQLVMSEEDTAALIL-----VHPEDRLVITGGEPLLQARLVALLKAERPALHVEIETNGTVAVHPALDPLVDQFNVSPKLSHSGNPAELALLPERLEAWARDPRAWFKFV---VADPSDLAEISALQDRFGIAPDHLFVMP......... 206
469 5.000e-39UniRef50_A0A2G6KGL0 7-carboxy-7-deazaguanine synthase QueE (Fragment) n=7 Tax=Bacteria TaxID=2 RepID=A0A2G6KGL0_9GAMM  ali  24  5...............SLKISELFFSLQGESSTSGLPTVFVRLTGCPLRCHYCDSEYA---------------FYGGQWRSFADIEAEIAAY-----GARYVCVTGGEPLAQACLPFLTRLCDAGYCVSLETAGALDIAAVDARVIMDLKTPASGEANRYENIEHLQAQDQIKFVLCDRADYDWARQRITELDLLDKC........................... 171
470 5.000e-39UniRef50_A0A2N1W684 7-carboxy-7-deazaguanine synthase n=1 Tax=Candidatus Goldbacteria bacterium HGW-Goldbacteria-1 TaxID=2013807 RepID=A0A2N1W684_9BA  ali  24  6...............QLFVCELFEDLEGEGRFQGYPTFFIRLSECNLRCNWCDTKESYA---------------KGKPYGITKLAKMASE-----SDCCNISITGGEPLLQKVLIKALRKKCPGKKITVETNGSISVAGLNDNVSMDIKLLSSGVSEKMSNLKVLKPKDQVKLVAGSLADLRYAQAVLKKHRTKAEIIAIREFILRRGLKWRAMVQLHKM.... 208
471 5.000e-39UniRef50_A0A1F6EJ09 Anaerobic ribonucleoside-triphosphate reductase activating protein n=2 Tax=Candidatus Kaiserbacteria TaxID=1752734 RepID=A0A1F6EJ  ali  15  14...............................YPGKTACIVYTIGCNFRCPYCHNPELVN-------ETVERTFSESRIFT---------FLESRRGVIDGVVITGGEPTMQDLLLFMRRVKERGFLVKLDTNGTNPNLNLVDYVAMDVKAPLSTYHRVVGRVDIGAIRRSIDTLLSSGVPYEFRTTVVKTLLSPEDLEGIAREIA-GASRYYLQ.......... 189
472 5.000e-39UniRef50_A0A2D6JLW6 7-carboxy-7-deazaguanine synthase n=1 Tax=Bdellovibrionaceae bacterium TaxID=2026715 RepID=A0A2D6JLW6_9PROT  ali  26  12......................FFTVQGEGLHTGRPAIFLRLSGCNLRCEWVNSDGT--TSLCDTPYSSHQPEKLLK--SIDEVVEDIKSY-----PCKYVVITGGEPYLQKIAPFISELKNLGYYVCIETNASIYFETEADFISMSPKLSDKSENYESHQKRRKNIEALASFTKQHDYQFKFVINTKDDLLEAKELIAEIEAIAKD--KILLMPQ........ 203
473 5.000e-39UniRef50_A0A2E2UZ07 7-carboxy-7-deazaguanine synthase n=1 Tax=bacterium TaxID=1869227 RepID=A0A2E2UZ07_9BACT  ali  39  9...............RYGVHKIFSTIQGEGAMAGLPVVFVRFTGCNMWDGRPETRADSTCPFCDTDFL------HGEMLSIRDIVDQVTELAA--PGVGWVWFSGGEPSLQMDKPLTMAIRQQGFSIGVETNGAKKFLSQIDHLVMSPKLPNSTAQRWCHSLKVLYPHPNIRPEHYSDVRAVTRWIQPIDAEDEKQNIELTIEKLFGLPKWRLSVQTHKVIGV. 222
474 5.000e-39UniRef50_A0A174KJH6 Glycyl-radical activating family protein n=120 Tax=Bacteria TaxID=2 RepID=A0A174KJH6_9CLOT  ali  15  7...............KGRIFDIFSIHDGPGIRT-----IVFLKGCILRCQWCCNPESQRFDIENMIVAGKNKI-IGQDVTVREVLEKIKQDRAYYKSGGGIALSGGECMCQPEFALLHECNEIGISTAIETTAAVDIIPEVDTILMDIKHTNSEKHKKFTGRDNKIILENAKIIAESDSDLIIRVPVIPTFNHTKEEIRDIARFAKTLKGVRLLLPYHRM.... 218
475 5.000e-39UniRef50_A0A1V6H425 7-carboxy-7-deazaguanine synthase n=1 Tax=Verrucomicrobia bacterium ADurb.Bin070 TaxID=1852927 RepID=A0A1V6H425_9BACT  ali  27  2..........KQDGGRIRVVEIFESLQGEGYNTGMPAVFLRLGGCNLACPWCDT-----------------AFDSFATLEEDEVVEQVATF-----ACKALIITGGEPLIHALGGLLERFKLLGHWIGVETNGLVPWRRRIDYLAVSPKA---LYAELYDDDRMVRQADEVRIVVDGDVDHYFLSPCDRGEVNVADAVRLLGRLNRGRKKWRLSLQTHKLAG.. 209
476 6.000e-39UniRef50_A0A0F0CL07 Pyruvate formate-lyase 1-activating enzyme n=180 Tax=Bacteria TaxID=2 RepID=A0A0F0CL07_9CLOT  ali  17  14...............................FPGHVACTIFTGGCNFRCPFCHNSDLLDNGADD-------------DYTEEEVFE---FLHKRKRVLEGVCITGGEPTLQPDLEFIRKVRELGLAVKLDTNGYKPELGLLDYVAMDIKASRDHYGEGAPGLNMELVDESIAFLLSGNTPYEFRTTVVRGLHTAEDFRKIGPWI-KGCPGYYLQ.......... 189
477 6.000e-39UniRef50_A0A2M9MDR9 7-carboxy-7-deazaguanine synthase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A2M9MDR9_9ACTN  ali  23  4.........................VQGEGPSAGQRCAFVRLGGCNLSCRWCDTPYTWDWTGMGDSGVAYDPRQELRPMAWTDVLRTLLDFE-----VPLIVVSGGEPLSQQLIPLLRELRAAGRKVEIETNGTVVPQDELVELGVRFNVSPKLSHSGDPESRRIVPAALRALAAVPETAFKFVC---RNRTDLDEVASLVDRYGTR--PVWIMP......... 185
478 6.000e-39UniRef50_V9VT23 7-carboxy-7-deazaguanine synthase n=17 Tax=Alphaproteobacteria TaxID=28211 RepID=V9VT23_9RHOB  ali  22  1..............MTLRIAEIFPTIQGEGALIGEPTVFVRAGGCDYRCSWCDSLHAVD----------SAYRHDWAVMAPEQVMAEVRRLSGGRPL--TVSISGGNPAIQDFAPVIAYGKAEGYRFACETQGSVPWFADLDTLVLSPKPPSSGETVDWKAFDQCLEQAVMKIVIFDDEDYAWAKVDPALPVDLSQATDRLLWLIEKGDGWRVLPQLHVLVW.. 229
479 7.000e-39UniRef50_A0A1V5WH20 7-carboxy-7-deazaguanine synthase n=1 Tax=Parcubacteria group bacterium ADurb.Bin216 TaxID=1852939 RepID=A0A1V5WH20_9BACT  ali  32  1..............MKYPIQETFTSLKGEGLYTGQPMHFIRLAGCNLKCEFCDT-----------------EFNKGKDIELTELVAGIA-----PSPISRVVITGGEPCLHSLKPLTDALHNVGKLTHLETNGTLPIIKLFDWIALSPKNMNCLSSSQADEIKFLVGFEGWKFIDNFLASYPIKTLYVMPITIIQENIDDAVEYCTLNPMFRYCIQLHKVLQIP 208
480 7.000e-39UniRef50_A0A2D9TPF5 7-carboxy-7-deazaguanine synthase n=2 Tax=Bacteroidetes TaxID=976 RepID=A0A2D9TPF5_9BACT  ali  29  1...................MESFXSIXGEGFHSGXPAXXIRLSGCDVXXXWCDVKESWDISKE-------------QYTXVXEIVNKVXK-----TSAELVVITGGEPLMHXLSDLTKALKKEDKKIHIETSGTHPFTGDFDWICFSPK-KFKKPLDIY-----FSISDELKIIICNKSDFKWALIMQPEWSREEVISPLILEYIKLNPKWRISVQTHKYLNV. 192
481 7.000e-39UniRef50_B2JY77 7-carboxy-7-deazaguanine synthase n=6 Tax=Burkholderiaceae TaxID=119060 RepID=B2JY77_PARP8  ali  26  15...............SYPVNEIFESLQGEGNFTGTPSVFVRLQGCPVGCAWCDSKHTWQVMPEREISVGAMGEKTGRPCDSYAWCDVTLANIVRAADAEHVVITGGEPCMYDLRPLIAKLQAWHHRVQVETSGTYPLVTPSTFVTTSPKMPSDEALERANEIKYVGKQRDIDIVLERLDPIQRARIWLQPLSLSSRATGICMK-AAHRYGWRVSLQTNKFINI. 234
482 7.000e-39UniRef50_A0A2D6FNK7 7-carboxy-7-deazaguanine synthase n=3 Tax=Bacteria TaxID=2 RepID=A0A2D6FNK7_9BACT  ali  31  2................LKVNEYFYSLQGEGYRAGHASIFIRLSDCDQTCGFCDT-----------------EFESGQELSNEELLVKIQEY-----PCQWIVWTGGEPTLQLTQSHVDYFKGKGYSQAIETNGNNRAPNGLDWVCVSPKVADKNFPDGVDELRYVRHANQLG-VPEPKVESKHLYLSPRGNDMNKKNLQKCTELILENPKWKLSLQSHKLLNV. 191
483 7.000e-39UniRef50_A0A212PFD9 7-carboxy-7-deazaguanine synthase n=1 Tax=Geobacter sp. DSM 9736 TaxID=1277350 RepID=A0A212PFD9_9DELT  ali  20  5...............SASIVELFSSIQGEGVLVGLRQAFLRFHGCNLACEYCDTRSDEPPEEALLEETPGRQDFERNPVPLERVARLLQLWESALPGIHHLSITGGEPLIHRCLQEWLPELRAILPVYLETNGILEVIPHLDYISMDIKLPSSSGCTGLWEEHRRRTTVFVKAVVSAEEDWEIRITCILQPVTRADALEMQEMAGRCLTDVRVIPQTHKFMG.. 248
484 8.000e-39UniRef50_A0A1G2ZKF1 7-carboxy-7-deazaguanine synthase n=1 Tax=Planctomycetes bacterium RBG_16_43_13 TaxID=1801967 RepID=A0A1G2ZKF1_9BACT  ali  20  4...............KGYLLEVFSSYQGEGIYAGVRQIFIRLGGCNIRCNYCDTPESWVFQKTYRVENPPESETFSNPVGTADIISVVKEYVANRAKYHSISITGGEPLVQAAFLLLPQLREFGLPIYLETNGTMAVIDLVDIVALDIKLPSPGV-----EMSWEDTAECISIASSKDVFVKIVVTQDSREEEIERAISLFSDIIKKGLNVHIMSQIHKLVG.. 251
485 8.000e-39UniRef50_W3Y6U1 7-carboxy-7-deazaguanine synthase n=6 Tax=Veillonella TaxID=29465 RepID=W3Y6U1_9FIRM  ali  20  1................MNVIEIFSSIDGEGSRQGFLTTFLRLYECNIRCSYCDTTYSYGPDSV------------YKQMSVQEVADTIESL-----GNHRITITGGEPLLQEREVIALIDELMPYDFNIETNGTIVPSFQRDWFTYDYKTPSSLAEESMNRFKGATERDLIKFVVGTVEDLECAHIYVSPVWGRIEAATIIEYMKAHNLNVKFQLQIHKFIWDP 230
486 8.000e-39UniRef50_G3Z4J9 7-carboxy-7-deazaguanine synthase n=1 Tax=Neisseria sp. GT4A_CT1 TaxID=665946 RepID=G3Z4J9_9NEIS  ali  28  129..........APENPQYRIVEIFESLQGEGWNTGMPAVFVRLGKCNLACGWCDTDYLKFG-----------------MMSLSDILGRLKTYTARN-----IIITGGEPTIQPHLDLLDALKAEGYFLCIETNGLKPAPPQIDYVATSPKACYAAKYSEADEVRIVADGDVVAFCMERKIRARRYYLSPCEQNGVMNIYDTIRQILNSRPDWQLSVQTHKWAGI. 333
487 9.000e-39UniRef50_UPI000931831C radical SAM protein n=1 Tax=Porphyromonadaceae bacterium FC4 TaxID=1720317 RepID=UPI000931831C  ali  28  1................MKVVEIFTSIQGEGANCGLLVTFVRLTGCNLSCLYCDT-----------------NFETGTEYSTEELTAAVTAEGTRR-----IIWTGGEPTLRLTEELVTHFADLGYWQAIETNGTKTPPRGLDYITVSPKVSVQTLRKNF----RDTPIDEIRYPVARGVDIDTRHYLLSPIFEPEPNLTYCLELMRQDPRWRLSVQLHKLLHLP 202
488 9.000e-39UniRef50_B6WPV8 7-carboxy-7-deazaguanine synthase n=2 Tax=Desulfovibrio piger TaxID=901 RepID=B6WPV8_9DELT  ali  33  3...............TLAVNEFFVTLQGEASFAGTPAVFVRFQGCPVACPWCDTQYAARLDGATLDFAAVRAKQGYADVEPEALLAAIREAGPR-----HVVLTGGEPCRHDLTELTSRLVTEGFRVQIETSGTMPIRCHADWVTLSPKLDMPGAWERAGEIKFDTAADLARFEQALAVARQAALVWLQPVSQGKEATRLCVEAAFAH-QWRVSVQVHKYL... 222
489 1.000e-38UniRef50_O67826 7-carboxy-7-deazaguanine synthase n=5 Tax=Aquificaceae TaxID=64898 RepID=QUEE_AQUAE  ali  23  13................IALNEVYESIQGEGLLVGLPSVFIRLQGCNLRCPWCDQPEALS--------------FSGRKVKLSSLINELKKFTA-----KHIVITGGEPFAHRELPFIEFLLSEGYSVQIETNGTLWVEEMEKFAGIHITCSPKGVAKYYVHPKILKYAKELKFVVDKKEEFERFKVVLQPESNRKEMMEKALKIQKELLKVRVIPQVHK..... 214
490 1.000e-38UniRef50_A0A1T4PNY7 Pyruvate formate-lyase-activating enzyme n=13 Tax=Bacteria TaxID=2 RepID=A0A1T4PNY7_9FUSO  ali  17  11...................HESFGTVDGPGIR-----YIVFLQGCPLRCRYCHNADTW------------EKNNAKYRETPEQTFKEICKYKNFIQS-GGVTLTGGEPLMQPDRELLKLCKKDGLHTAVDTSGYFEALEYTDLVLLDIKCIDPETHKSLTRVELDPVLKFAQYLKEIGKKTWIRHVIVPGITDNDEYLNKLADYVKTLDNV............. 192
491 1.000e-38UniRef50_A0A2A3K538 7-carboxy-7-deazaguanine synthase n=2 Tax=Clostridioides difficile TaxID=1496 RepID=A0A2A3K538_CLODI  ali  27  1..............MLYNVCQIFKSVQGEGKNAGRSTVFIRLSGCNMKCTFCD-----------------EDFENCVQMDVESILKEIQKLEPFS----MIVITGGEPTIQDLEQLIFKLKQKRYYISIETNGINNNIPKCDWITCSPKTLNKIAYANELKFVINKKKDEVNFINTILKEVRYDYICLQPESNKEECILTCLELINENPNFNLSLQQHKFINI. 194
492 1.000e-38UniRef50_A0A2A3HMT7 7-carboxy-7-deazaguanine synthase n=1 Tax=Streptomyces sp. TLI_235 TaxID=1938860 RepID=A0A2A3HMT7_9ACTN  ali  23  1MTTTDVTLSRSRPRDVL-VCEVFPTIQGEGPSAGQLASFLRLGDCNLACDSCDTPYSWDWKRYSRVEQTSR-------VSAEDVAAELLR-----HPTKLVIITGGEPMMQQLLPTADRLTGAGRRIEIETNGTIAPDPTFDHVSL-YVVSPKLAHMGMPASRRIKPAVLEAFQATGRAVFKFVLDTPA---DVEEVAALQDE--HGLEQVWVMPQ........ 201
493 1.000e-38UniRef50_A0A0G3EG43 7-carboxy-7-deazaguanine synthase n=2 Tax=Kiritimatiella glycovorans TaxID=1307763 RepID=A0A0G3EG43_9BACT  ali  24  2..NETDAVAPRGAAPTAELIEIFSSIQGEGLCVGERHLFVRFAGCHRRCAYCDTPVKAGSTFRVESPAGSGHFTVANPVEPQRLIDEIDTLKRPSGLHAAVALTGGEPLLQTDFLLLPLLKSEGLRVLLETAGDHPIAPWVDSVALDAKLPQATESTDWERVGRCVKLAFVKAVIAASTDLPLVLQPVPEPPSARRLLELQAFLAQNALEVRIIPQCHHTLGM. 258
494 1.000e-38UniRef50_R7NIX3 Pyruvate formate-lyase-activating enzyme n=11 Tax=Terrabacteria group TaxID=1783272 RepID=R7NIX3_9MOLU  ali  20  1..............MKSSVNETFGLVDGPGIRT-----VIFLNGCKLRCLYCHNPETWKM--------------GELNYTTDELVAKIIRNKPYFKNNGGVTFSGGEPLLQIDFLICKKLKAENIHIALDTAGYEEILSLIDLVILDIKHPNKEGYKKLTGTSIDESEKFIECLNKSNKPVWIRQVIVPGIMDNENYLKELADYLTKIKNI............. 188
495 1.000e-38UniRef50_O27295 7-carboxy-7-deazaguanine synthase n=22 Tax=Methanobacteriales TaxID=2158 RepID=QUEE_METTH  ali  22  4..............MRAPIVEVFSSIQGEGLLVGRRQIFVRFAGCNLNCSYCDTPESRDPS-------------AGRLFTAPELTEIIEGLIT--PDFHSISITGGEPLLYPDFITELLE-ESPHRTLLETNGSLPIAHLFDYASVDIKHFSDNLRSGTTESDISSPGDLIDILISRGVNTYCKVVVMPTGALAERLLECVDELLEKYMDVYVIPQMHRALGL. 246
496 1.000e-38UniRef50_A0A0F9KI53 Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=A0A0F9KI53_9ZZZZ  ali  26  1................MKINEIFASIQGEGQYQGLPTVFTRLQGCNLFCTYCDTSYAQLGD-------------SGEELTVEGVIQRVDRLSPRSKS--WICITGGEPLRQIDEELVRELKRQQYLIEIETNGSLPKPRWVDSWCADIKCPSSGVVSKEEWFKT-RPKDQIKFVVGTEEDLVFAVVLISPVINLTQILQRVVEFCLKH-RVQFSLQWHKV.... 223
497 1.000e-38UniRef50_R7B515 7-carboxy-7-deazaguanine synthase n=8 Tax=Terrabacteria group TaxID=1783272 RepID=R7B515_9ACTN  ali  23  5...............SFPIAERFVSINGEGAHAGKLAAFIRFPGCNLDCSYCDTQWARDPELTV------------EFVSVEELCDWVE-----SEGVTCVTITGGEPTLQSDLLHALARLEAVEVVEIETNGSTDLAKLIAHITMDYKLPSSGMEDKMENFELLGEHDVVKFVVGSHEDLERMVEVVREHELATRCQVYIVDFMRERTHARLQLQLHKFIW.. 237
498 1.000e-38UniRef50_A0A1F5ATT4 Uncharacterized protein (Fragment) n=1 Tax=Candidatus Aminicenantes bacterium RBG_13_59_9 TaxID=1797268 RepID=A0A1F5ATT4_9BACT :_  ali  31  2................LKTAEIFSSVQGEGLRQGEPTLFIRFTGCNLRCSFCDTKYAWEP---------------GSDMSVERIMQRVQAARKVF-PARWVCLTGGEPLLQDLAPLVGRLKRAKLNVQVETNGTLGRDWPVDWWTVSPKPP------AWKTAAFFRKKASVKLVVTRRLTLE.......................................... 146
499 1.000e-38UniRef50_A0A1B6BBN4 Pyruvate formate-lyase activating enzyme n=1 Tax=Fusibacter sp. 3D3 TaxID=1048380 RepID=A0A1B6BBN4_9FIRM  ali  20  1MNLKRHGPMTPA----LNVFESMGTLDGPGIRT-----VIFLKGCPLRCHYCHNPESWQDQTE-------------NWMQQDELMALIMKMKPYYKNGGGVTFSGGEPLLQKLEPLCKRLKAEGIHVALDTSGCILLLEVVDLIILDVKHAESEAYTALTGGALSKTLEFLEFIKAIHKPYWIRQVIVPDYNDQKSLV.......................... 186
500 1.000e-38UniRef50_O31677 7-carboxy-7-deazaguanine synthase n=125 Tax=Bacilli TaxID=91061 RepID=QUEE_BACSU  ali  21  5................IPVLEIFPTIQGEGMVIGQKTMFVRTAGCDYSCSWCDSAFTWDGS----------AKKDIRWMTAEEIFAELKDI--GGDAFSHVTISGGNPLLKQLDAFIELLKENNIRAALETQGTVDWFTLIDDLTISPKPPSSKMVTNFQKLDHIQHAVSLKVVIFNDEDLEFAKTVHKRYPGIPDDQSLIAHLLAELNLVRVLPQLHTLLW.. 237
501 2.000e-38UniRef50_A0A2R4ZQE0 7-carboxy-7-deazaguanine synthase n=2 Tax=Desulfurococcaceae archaeon AG1 TaxID=2027460 RepID=A0A2R4ZQE0_9CREN  ali  23  25................IAVSETFKSFQGEGPSAGRPAIFLRLQGCNLSCVWCDTIDIWV---------------KGHVYSYEDLLDEARGWIDDLRNDHMLVMTGGEPMLQREIEGLLRIFVERYRIEVETNGTIPPSQEIERYVDQFNVSPKLSNSGMPRTIRFRRDVLRRFVETGKAIFKFVVV---GERDIEEVMEYIDAIPIPPERVYLMP......... 212