Scheduled maintenance will begin on May 30th, 2025. Server will be temporarily unavailable — learn more.
current user: public
If you have questions about the server, please let us know.

Query: PF02659.15; MNTP_SHIDS/30-182; Putative manganese efflux pump, from PfamA32U

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150
# Score Template Links and tools%idFirst KPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGSIIGKKAEILGGLVLIGIGVQILLast
1 -42.800[S] COG1971 Predicted membrane protein  ali follow..  23  31KIPFKSLLFIAGCSAVSILIAMGFGMTIQQYLSP---AIAESLGGIILILIGCWALYQAFRPAKNGDFDNSGAITGREAVILGIALSLDAFGAGIGAALIGFHPLYMAVSVAVMSALFVSLGMKSGYRFASYWIKRFSFIPGLLLVLIGVFNL 211
2 -13.700[S] KOG2881 Predicted membrane protein  ali follow..  15  98........RLTVFSGAMLALMTVLSACLGWITQVIPRAVTYYLSTALFALFGLKMLHEGWTMSPNEGQEGYEEAQIEAFSLTFVAEWGDRSQLTTIILGARENIAGVIGGGILGHALCTGIAVIGGKIVAQRISVRVTLIGGVVFLLFALSAL 286
3 -12.400[S] COG2119 Predicted membrane protein  ali follow..  7  46RYRKPIPIIAAIFLAT--LANHALAAWLGVVVADYLSDILKWVLVVSFLAMAGWILIPDKLDGEESISTRGPFVASFIAFFMA-KTQIATSILGAQYADALSWVIVGTTL-----LLANVPVVLIGKLSADKMPGLIRKVTAGLFLLMALATA 198
4 -10.800[R] COG1279 Lysine efflux permease  ali follow..  14  48...............LVLICAGIFGGSALLMQSPWLLALVTWGGVVFLLWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATMLAVTW-VVLGSLGGQLDVEPKRWFALGTISASFLWFFGLAILAAWLAPRLRRIINLVVGCVMWFIALQLA 199
5 -10.700[P] COG4300 Predicted permease, cadmium resistance protein  ali follow..  17  44......................YLGQFLGSVSLILLSLLFAFLLGLIPILLGIKVLLLGDSDGEAIAKEGLRKDNFLVAMITFASCGADNIGVFVPYTLNLANLIVALLTFLVMIYLLVFSAQKLAQVVGETLEKYSRWFVAVVYLGLGIYIL 194
6 -10.200[E] COG1280 Putative threonine efflux protein  ali follow..  17  27......ALTLGMSVGYRRTLWMMVGELLGVALVAVSAVVGKIVGASYLVYLGVQMWRSRGKLAINIEQENTYQGSDWGLLVQGFVTAINPKGWAFMVSLLPPQLTVLVAIILLSEFISMSLYATGGKGLKRLLSRLLNRIAGSLMAGVGIWLY 204
7 -10.100[R] COG2215 ABC-type uncharacterized transport system, permease component  ali follow..  16  111ETELKRGVLLSFLSSILQGVVAILLIGAVYLVLRGATRALEIASYALIAAFGGWLVFRKLRSMLRPAPAPATVHA--ALIVLSFALLNGLYLGGVLSVFIGTAITVSILATMAVTAKGIAVRYASSDSAAARISNGIEIAGALLVLLLGLVLL 338
8 -10.000[U] COG2095 Multiple antibiotic transporter  ali follow..  15  41..KNKTAATANIAVAIILIIALLAGQMLLDLFSISLDSF-RVAGGLLLLSIAFSMMSGKLGEDKQNKQEKSEYISREQIAVVPLAMPLMAGPGAISSTIVTLGIILTVVAFSFCSWLLFRSAPYIVRLLGQTGINVITRIMGLILGALGIEFI 200
9 -9.520[S] KOG3140 Predicted membrane protein  ali follow..  9  135.........LSILSGF------LYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHRINYIIFLRITPFLPNWFINITSPVINVPLFFIGTFLGVASFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAV..... 274
10 -9.160[S] COG4280 Predicted membrane protein  ali follow..  12  45..................IAVLSVAIALGTGLQFLPLQPLQIVIGGLLLWFGWGWAKKSVRRVLDQESTGFSKLNFLIMTKSVALEALEIFVIVITLGLATSAWYEAIAATGFALLLSLVFVIFLHPYLVKLPEVLIKLGAGIMLSAMGT... 196
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.