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Query: PF07476.11; A8AJ73_CITK8/162-410; Methylaspartate ammonia-lyase C-terminus, from PfamA32U

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst CVPEAIPLFGQSGDDRYIAVDKMILKGVDVLPHALINNVEEKLGFQGEKLREYVRWLSDRILSLRTSPRYHPTLHIDVYGTIGLIFDMDPVRCAEYIASLEKEAQGLPLYIEGPVDAGNKPDQIRLLTAITKELTRLGSGVKIVADEWCNTYQDIVDFTDAGSCHMVQIKTPDLGGIHNIVDAVLYCNKHGMEAYQGGTCNETEISARTCVHVALAARPMRMLVKPGMGFDEGLNIVFNEMNRTIALLQLast
1 -69.100[E] COG3799 Methylaspartate ammonia-lyase  ali follow..  41  162.PTHRVPIYCQSGDARELNVDKMILK-AVDVLPHGLINSRQKFGVDGQTFMEFVKWVVTRTRQIGSP-GYHPVLHFDVYGWIGEEIGLEPQRIADFICRVADSVPDFTLNIESPADFGSTQAQIENYAKIVSILDNRGSSARIVVDERCNTFEDIRLFAEAKATHLVQIKTPDVGSIADTARAVLLCKTNKVGAYVGGSCTETDLSAQASVHVSVATQADMMLAKPGMGVDEAFSIVGNEQNRLLAMLN 407
2 -45.800[H] COG1441 O-succinylbenzoate synthase  ali follow..  11  97.TLPQAANYRTAP----NGDPDDLILKLADM--PGEKVAKVKVGLY------EAVRDGMVVNLLLEAI-PDLHLRLDANR------AWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRD-----------DSRAFARETGIAIAWDESLREPDFA--FVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVI-SSSIESSLGLTQLARIAAWLTPDTIPGLDTLDL-MQAQQVRRWPGSTLPVVE 312
3 -37.900[MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily  ali follow..  11  101....NQPVHQMLGGLCHDRIPTDAGALAENLLEQGISAMKIWPFDGRYITSEQLRAALLPFEQIRKRVGDRMQIMVEFHSL------WNLPTIKKIARELEAFD---PTWYEDPIRMNSVSALSEL---------AASTSVPICASETLGSRFPYKDMLEAGAIGIVMTDLVWTGGLTEGRKIAALADTYHRPYAPHDCT--GPVAYAAAVHSSFSQTNTMIQE......................... 346
4 -16.700[G] COG0148 Enolase  ali follow..  14  148....PVPMMNVINGGAHADNNVDFQEEALRWGAEVFAVLGGGVGDEGTSNQQALDILIEAIEQAGYKPGSQIALAMDIAASEFFKNG-SPQEFIDYQAKL--VSQYPIVSIEDGLHEDDWESWKGLTTSLGTKTQ-------LVGDDMVTNPVRLQKSIDLGVANAILIKLNQIGTLSETLETISLATRHSYRSVISHRSGETEDTTIADLAVATRV................................ 388
5 -13.100[G] KOG2670 Enolase  ali follow..  12  179..............REAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGLENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKY-SPDQLADLYKSF--IKDYPVVSIEDPFDQDDWGAWQKFTASAG---------IQVVGDDTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCT................................ 390
6 -9.610[C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family  ali follow..  12  130.........HELSHEEILQLIDNFARCAQLAREAGYDGVEVMGSEGGGDYRNRMRFAVEVVRAVRERVGNDFIIIYRLSMLDLVEDGGTFAETVELAQAIEAAGATIINTHEARIPTIATPVPRGAFSWVTRKL-KGHVSLPLVTTNRINDPQVADDILSRGDADMVSM................................................................................ 310
7 -9.040[CR] KOG0134 NADH:flavin oxidoreductase/12-oxophytodienoate reductase  ali follow..  5  170................ETEVVDRFVYAAKFAYECGFDGIQLHGAHGGGSLENRQRIVIEIYDAIRAEISTGFLIGIKTNSVEFQSEGLTLEDAKTMCQVYESKGFDFVELLNWTWERESTKKREAFFVEFAEQIRPVFNKTVVYLTGGFRTVSAMINAISCNATQGIGL................................................................................ 349
8 -8.330[E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase  ali follow..  9  45...EWLHVVDLNGAFAGETVNGAAVDAILKATKGGIRTLELSRGLKRVILGTVAVRDPALVIEACRKFPGRVAVGIDAKGGKVAVEGWAEASELGVVELARKFEGAGVAAI---YTDIDRDGILTGINWASTLELADAVSIPVIASGGLASMDDIRRMTEPDAQKLEGAISGRA-DPKEALDLIREARKGKL......................................................... 247
9 -8.180[J] KOG2335 tRNA-dihydrouridine synthase  ali follow..  13  75......SLILQFGVD-----DPVILEKAAQLVGPYVDGIGINCG--GSALLDEPEKVHKLVRAVKSTLGESFCTEVKIR---------DLNKTRHLMQVIEKSGADIIT-VHGRTRQDRSSFPVN-LDAIRE--VRPCVQIPVVANGDVKSLRKGLEIAKYTETQGIMSARGLLEN......................................................................... 238
10 -8.090[J] KOG2334 tRNA-dihydrouridine synthase  ali follow..  15  289..EEKSRVVFQMGTS-----DAVRALKASEIVCNDVATIDINMG--GAALLSKPELIHDILATLKRNLDVPVTCKI--------RLLKSPADTVELARRIEKLGVPALA-VHGRKIADRPRDPAK-WDEIAD--VVAALSIPVIANGDVLEYDDFSRIKTATGAASVMV................................................................................ 447
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 1 0 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;