current user: public

If you have questions about the server, please let us know.

Query: PF13826.6; G7XTL7_ASPKW/119-243; Domain of unknown function (DUF4188 topsan), from PfamA32U

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .
# Score Template Links and tools%idFirst IVVFHLGARNHHPLGMFAPGMKELGDSAEKMQRDMRANPVKYGLLGSSQWLKCDSAAGNEFMTVFYLRDYAALHQFAHDEIHMEGVRWWARIAKDHPHLALYHETYLVPRGNWENIYINGWPTGLLast
1 -14.600[S] COG3224 Uncharacterized protein conserved in bacteria  ali follow..  15.FEYHFAHRVTP------DHHEIFLECQEQLKILVTKYP---GYISSESTELRSEGDIFVAETVIRFDTLENFMGWIDSPERRQLIYLEENAGYQFEGKVN........................ 105
2 -11.400[R] COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides  ali follow..  1MIYEIAMLPVQK------DKISEFRQAFGDVVPLLKRAR---GYRGHVLAQGVETP--EVFNLIVRWRSLNDTPGFEASEDHEQFMEGIQDYFSGEPTVYHLEGD.................... 95
3 -11.300[S] COG1359 Uncharacterized conserved protein  ali follow..  15  1MLIQMVSINVKQ---------GHAADFLEAFRINYEGTRQEPGNLRFDVLRNPDDD--HSFVIYEVFKSPEALDAHRKTEHYQECVRRIDPILAGPRTKTFY....................... 91
4 -6.600[S] COG3542 Uncharacterized conserved protein  ali follow..  13  1.....................MGTDMSAQAIIRELGLEPHPEGGFYHQTFRDKAGGERGHSTAIYYLLEKGVRSHWHRVTDAVEVWHYYA................................... 69
5 -5.650[A] KOG3408 U1-like Zn-finger-containing protein, probabl erole in RNA processing/splicing  ali follow..  12  64.................................................................YFDSSQALLVHKKGKVHKRRLKNLREEPYTQEE........................... 96
6 -5.650[R] COG5112 U1-like Zn-finger-containing protein  ali follow..  12  64.................................................................YFDSSQALLVHKKGKVHKRRLKNLREEPYTQEE........................... 96
7 -5.400[T] KOG3860 Acyltransferase required for palmitoylation of Hedgehog (Hh) family of secreted signaling proteins  ali follow..  12  384...........................................LDGIDTPENMIRCVDNNYSSLAFWRAWHSYNKWVVRYIYIPLGGSKNRVLTS---VAIWHDI.................... 449
8 -5.320[T] KOG4801 Member of the steroid/thyroid receptor superfamily  ali follow..  14  211.TTFVLGSRANKALG-MGGTRGRIYIKHPHLFKYAADPQDKHWLAEQHHMRATGGK-------MAYLLIEEDIRDLAASDDYRG......................................... 285
9 -5.310[U] KOG3372 Signal peptidase complex subunit  ali follow..  1..MNTVLSRANSLFAFSLSVMA-ITTAFKDRSVPVRLHVSRIMLKNVEDFTGPRERSDLGFITFDITADLENIFDWNVKQLFLYLSAEYSTKNNALNQVVLWDKIVKLLLKDMKTKY........ 127
10 -5.300[S] KOG2706 Predicted membrane protein  ali follow..  267.VCTMAGFGAYPDESDPNNGEGPRKRYQHLKRDADKHTYNFTTIVNTRVLEVERCWTFREG--MKHWN---CVQYWLAVNVYKLFPSKKYRTGATLLCSAYWHGFR................... 367

FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.