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Query: PF02424.15; C5BM31_TERTT/32-314; ApbE family, from PfamA32U

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGTEVSITFWHDDPAQAQQLLADGMAEMRRLDRELSPWIESSELATLNRLAAKAPQKISSEMLFLVDKSLYFSHLTHGAFDITFASVGWFYDYREKKQPSEAQRSALLPAINYRWLKLDKTAGTLAYAHDNVRIDLGGIAKGYAVDRVAQLLENAGVRNATISAGGDSQIVGDKRGKPWIIGIKNPRDGGKEEAEAAILLPLENTAISTSGDYERYFIDQKTGERVHHIINPRTGKSVEGVVSVTILGPRGSDTDPMSTSVFVLGVEKGLALVNSLANFECIILast
1 -93.900IDP05325 hypothetical protein CD2483 [Clostridium difficile 630] CD2483 [Peptoclostridium difficile 630]  ali follow..  31  29LGTVNEVTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFFVVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKVPSDSEIQKLLPLIDYKNIILDEKNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEGKNDKPFKIGIQDPTSKN---GESIGNIETTNKSVVTSGIYERFI--EKDGKIYHHMLNPFTGYPFENLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINKIDNVDAIF 310
2 -90.400IDP04513 putative thiamin biosynthesis lipoprotein ApbE [Clostridium perfringens ATCC 13124] CPF_2363 [Clostridium perfringens ATCC 13124]  ali follow..  31  45LGTVVSGVAYGDN---AKEALEKAFNRAKDIENMMSVNIENSELSKVNSEAFHKSVKLSDDLYYVIEKSIYYANLTDGALDPTIGHVIDSWGIGTENIPEKTLIDKYKDLKNYKNIELNPHTKEIRFLNENIKLDLGAIGKGYAGDEMRKVLREEGINSALLNLGGNVVALGKINNENWSIGIRNPKEEN----EISASVKINDEVVVTSGNYERYF--IKDGVRYHHILDPSTAYPAEGLISSTIITKNGIDADALSTATYILGAEKAKKLIEGLDGVEALF 322
3 -88.200IDP05247 hypothetical protein lmo2636 [Listeria monocytogenes EGD-e] lmo2636 [Listeria monocytogenes EGD-e]  ali follow..  28  49MGTVVTLKIYDKG---KEDVLDKGFDRIKDLAAKITTSEKTSEVDKINEQAGKKPVKVSEDVYYLIQEGLKYSENSGGSFDITIGPLTSLWHIGFSRKPSQAEIDAVLPLINYKDVKMNDKDQTVYLEKEGMELDLGAIAKGFITDETLKVFKENKVTTSIIDLGGNIYVQGNPNGNKWNVGIQDPFSPR---GSVIGKLPESNMSIVTSGIYERYL--EVDGKTYHHILDPKTGYPFDNIAGVSIVSKKSIDGDGLSTATFSKGIKGGMDYIEQFEGVDAIF 329
4 -83.700IDP04503 thiamin biosynthesis lipoprotein ApbE [Vibrio cholerae O1 biovar eltor str. N16961] VC2289 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  27  64MGTTYNIKYIQQPGIDSKTLQTEIDRLLEEVNDQMSTYRKDSELSRFNQHTSSEPFAVSTQTLTVVKEAIRLNGLTEGALDVTVGPLVNLWGFGPEVVPTDEELNARRAITGIEHLTIE--GNTLSKDIPELYVDLSTIAKGWGVDVVADYLQSQGIENYMVEIGGEIRLKGNRDGVPWRIAIEKPSVDQ---RSVQEIIEPGDYAIATSGDYRNYF--EQDGVRYSHIIDPTTGRPINNVVSVTVLDKSCMTADGLATGLMVMGEERGMAVAEAN-QIPVLM 345
5 -6.480IDP04680 sensor histidine kinase, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA3066 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  7  158.....QLYYLEGEYKGQAPVLESLYEQIQYISDLTNEFNMQSTETLENTYIVHDEVNIHNLIETMIKKWSYLYSIHKIELVYNPQDKELIWNSNELWIQRDNIFQNVLKHSKAKKLKIIIDEDIVYFRDNGIGFDINSKGTGLGLKNIEDISKMF---------DIKYTLQSNSEGTMFSFEN.................................................................................................... 328
6 -6.260IDP95076 hypothetical protein CD630_11560 [Peptoclostridium difficile 630] YP_001087648 [Peptoclostridium difficile 630]  ali follow..  11  1...........................MKKIRKLATKSCMSVTVYGMTAKDVTAKTPKSYVAGTNSIYGPKLSQAQLNSVAQATADFM-----NKKITKNMTTDAKIRVAYNHNNTTYVNWNAAEGANTAYTLVTKKGACSGMCR-SLKALCDAMGIECYYVH--------STTNDHQWNL------------------IRFED------------------GRLYH--VDIDANKSAGA........................................... 172
7 -6.250IDP00074 gene: pyrG; CTP synthetase NT01ST3685 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  15  13.......................................................................................................................................VSSLGKGIAAASLAAILEARGLNVTIMKLDPYINV---------DPGTMSPIQHGE-----VFVTEDGAETDLDLGHYERFIRTKMSGRIYSDVLRKELGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAI. 157
8 -5.920IDP05354 hypothetical protein CD3043 [Clostridium difficile 630] CD3043 [Peptoclostridium difficile 630]  ali follow..  12  42................................................KLSQAQLNSVAQATADFMNKKIT---------------------------KNMTTDAKILVAYNHNNTTYVDWNAVEGANTAYTLVTKKGACSGMA-RSMKALCDAMGIESYYVH--------STSNDHQWNL------------------IRFGD------------------GRLYH--VDIDANKSAGKDIIYKSLSHP................................. 171
9 -5.910IDP00154 gene: pyrG; CTP synthase VC2448 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  15  13.......................................................................................................................................VSSLGKGIAAASLAAILEARGLKVTMMKLDPYINV---------DPGTMSPTQHGE-----VFVTEDGAETDLDLGHYERFIRTKMTGRVYADVLRKERGATIQVIPHITNAIKDRVIAGSEGHDIAIVEVGGTVGDIESLPFMEAI. 157
10 -5.760IDP02574 protease, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA1995 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  68.........YKTKDRNARNIMDELYGEFNKIADEYVKYNIASTRYSIKGLPGNYTFTLQVKYRESKEQTQYVKSQAKAIIGSIVK-------------PGMDEHEKVKAIHDYVVKHVSYDTSYQAYTAYEALANRSAVCQGYTL-LTYELLKEAGIQNRIVT--GT----GNGQAHSWNL------------------VNIENK--TTFDD-YSYFNMSDEQLSKDHDWD-RSKYPAATTSYFNELTNKIKAGSSKTATY...................... 294
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;