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Query: PF02737.18; Q2YR99_BRUA2/5-183; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain, from PfamA32U

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst TVGIIGAGQMGSGIAHVCALAGYNVLLHDAAPDRLEKGIATINGNMARQVASGKLQEEQRADAMKLIRPANSMEDLAGVDLAIEAATEDETIKRKIFAQLCPVLNPEAILATNTSSISITRLASTTDRPERFIGIHFMNPVPVMKLVELVRGIATEEDTFRKSNDFVTALGKTVTVAEDLast
1 -75.800IDP05101 gene: hbd; 3-hydroxybutyryl-CoA dehydrogenase [Clostridium difficile 630] CD1058 [Peptoclostridium difficile 630]  ali follow..  37  2KLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVTFDTVFELSKSINKVPVDVSE 180
2 -68.000IDP00503 gene: fadB; multifunctional fatty acid oxidation complex subunit alpha YPO3766 [Yersinia pestis CO92]  ali follow..  32  315LAAVLGAGIMGGGIAYQSALKSVPVIMKDINENSLDLGMNEAAKLLNKQLERGKVDGLKMASILATIRPTLDYAGIERAQVIVEAVVENPKVKAAVLAEVEALIGEDTVLASNTSTIPIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGAKTSDKTLAAVVAYATQMGKTPIVVND 493
3 -67.400IDP00999 gene: fadJ; multifunctional fatty acid oxidation complex subunit alpha STM2388 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  25  311VGILGGGLMGGGIAWVTACKGGLPVRIKDINTQGINHALKYSWDLLETKVRRRHIKASERDKQLALISGSTDYRGFSHRDLVIEAVFEDLPLKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAANAARPEQVIGLHFFSPVEKMPLVEVIPHASTSAQTIATTVKLAKKQGKTPIVVSD 489
4 -64.500IDP00545 gene: fadJ; multifunctional fatty acid oxidation complex subunit alpha YPO2747 [Yersinia pestis CO92]  ali follow..  26  345VGVLGGGLMGGGIANVTATRAGLPVRIKDINPQGINQALKYTWDALGKRVRSKRMRPTEQQRQMMLISGSTDYRGFERVDIVVEAVFEDLSLKQQMVADIERFGAAHTIFASNTSSLPISQIAALAQRPEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIATTVALARKQGKTAIVVAD 523
5 -64.400IDP04410 fatty oxidation complex, alpha subunit [Vibrio cholerae O1 biovar El Tor str. N16961] VC1047 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  30  331AVGVLGGGLMGAGISHVTVKAKTSVRIKDVANDGVLNALNYNYKLFDKQRQRKILTKAQLQAQMSQLSGGTGFVGFDRCDVVIEAVFEDLKLKQQMVADIEANAKPTTIFATNTSSLPIHQIASQAQRPQNIVGLHYFSPVEKMPLVEVIPHATTSDETIATVVTLARKQGKTPIVVKD 510
6 -55.900IDP02583 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein [Bacillus anthracis str. `Ames Ancestor`] GBAA5249 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  30  6KAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDQKHFLGTHFFNPPRYLKLLEVIPTKKTDPQVLSFMKLFGEDLGKGVVIAKD 203
7 -51.300IDP04044 gene: fadB/acbP; fusion product of 3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding protein [Francisella tularensis subsp. tularensis SCHU S4] FTT1530 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  31  119KIAVLGAGTMGAQIAAHFANAKFPVVLFDLKSQQGSAN-VIIEDSLAKLTKLNPFGSKDSIKYITPANYEDNLELLADCDLIIEAVAERIDIKESLYTKISSHIKENAILASNTSGLSITKLAQVLPENVNFCGVHFFNPPRYMPLVELIPHADTNSEILDKLETFLEKLGKSIIRAKD 301
8 -12.500IDP06064 3-hydroxyacid dehydrogenase [Helicobacter pylori J99] NP_223303 [Helicobacter pylori J99]  ali follow..  15  2KIGWIGLGAMGTPMATRLRDAGLEVSVYNRTESKAAP-----------LKEKGVAVYTSPIDL------------AAKVDLVFTMLSDKAAIDAVLAPKFWEQMSKKIVVNMSTIA---PLESLSLEKIAQKHQATYLEAAKAGALLILAAG---DEEVISKLKPVLAHLGSQTFYLGK 159
9 -11.500IDP90757 gene: ilvC; ketol-acid reductoisomerase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0632 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  15  20KVAIIGFGSQGHAHAMNLRDNGVNVTIGLREGS-----------------------VSAVKAKNAGFEVVSVSEASKIADVIMILAPDEIQADIFNVEIKPNLSEGKAIAFAHGFNIHYGQIVV....................................................... 120
10 -11.000IDP02330 gene: ilvC-1; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1419 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  17  19KVAIIGYGSQGHAHAQNLRDNGFDVVVGLRKGKSWDKAKED-------------------------FSVYTVAEAAKQADVVMILLPDELQPE-VYEEEIAPNLQAGNSLV.................................................................... 104
11 -11.000IDP02524 gene: ilvC-2; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1852 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  16  18TVAVIGYGSQGHAQAQNLRDSGVEVVVGVRPGKSFEVAKAD-------------------------FEVMSVSEAVRTAQVVQMLLPDE-QQAHVYKAEVEENLREGQMLLFSHG................................................................ 107
12 -10.800IDP90565 ketol-acid reductoisomerase [Vibrio cholerae O1 biovar eltor str. N16961] VC0162 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  13  39KVVIVGCGAQGLNQGLNMRDSGLDVSYALRQAAIDEQ------------------RQSFKNAKNNGFNVGSYEQLIPTADLVINLTPD--KQHTSVVNAVMPLMKQGAALGYSHGF-DITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPQGEGWEIAKAWAAATG........ 199
13 -10.400IDP91958 Trk family potassium uptake protein [Streptococcus pneumoniae str. Canada MDR_19A] SpneCM_010100004562 [Streptococcus pneumoniae str. Canada MDR_19A]  ali follow..  16  5TIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEPVLARGVIGDITDEELLRS---------------AGIDTCDTVVVATGENLESSVLAVMHCKSL-GVPTVIAKVKSQTAKKVLADSVISPEYEMGQSLAQTILFHNSVDVFQ............................ 143
14 -10.300IDP00666 TrkA potassium uptake family protein SACOL1096 [Staphylococcus aureus subsp. aureus COL]  ali follow..  15  4EYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKS---------------LGIRNFDHVIVAIGENIQ-SSTLTTLILKELGVKKVTAKAQNDYHAKILADTVVHPERDMGRRIAHNVASASVLDYLE............................ 142
15 -10.200IDP90709 gene: ubiG; 3-demethylubiquinone-9 3-methyltransferase [Yersinia pestis CO92] YPO1215 [Yersinia pestis CO92]  ali follow..  13  60...VLDVGCGGGILAESMAREGAQVTGLDMGYEPLQVARLHALETGVKLEYVQETVENHAQQHPQHY------------DVVTCMMLEHVPDPASVVRACAQLVKPGGHVFFSTINRNTKSWLMAVVGAEYLLGTHFIRPSELIGWVD............................... 202
16 -10.100IDP01104 potassium uptake protein, TrkA family BA_4191 [Bacillus anthracis str. Ames]  ali follow..  15  7EFAVIGLGRFGGSICRELAQLGMEVMAIDSDEDKINEFANIASHAVIADSTDEMVLKS---------------LGIRNFDHVVVAIGDNLN-SSILTTLILKELGVKNITVKAQNDYHEKVLADHIVHPERDMGKRIANNIASSNVLDYL............................. 144
17 -9.590IDP02492 gene: proC; pyrroline-5-carboxylate reductase [Francisella tularensis subsp. tularensis SCHU S4] FTT1559c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  11  2KICFIGGGNMAAAMIAGMTSHGYDIIVFDRNEHKCLN----------------------LIKKYNINTSTSLLNTIKLADVLILAI--KPQNMFELIKNIRDTVTSTQVIVTVAAGIQTSAYEELFNKEISFARTIPNTPSSLYGATGIFFNKVIAADKKDLVIDIMQTMGVVTVVEDE 160
18 -9.470IDP02372 gene: mdh; lactate dehydrogenase [Francisella tularensis subsp. tularensis SCHU S4] FTT0535c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  17  5KITLVGAGNIGGTLAHLALIKQLDVVLFDIAQGMPNGKALDLLQTCPIEGVDFK------------VRGTNDYKDLENSDVVIDLLGINIKVMQTVGEGIKHNCPNAFVIITNPLDIMVNMLQKFSGVPNKIVGM............................................ 144
19 -9.350IDP92100 malate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_118430 [Toxoplasma gondii ME49]  ali follow..  15  159KIGLIGGGNIGATLALLSAVKELDVVMFDVVQDLPQGKCLDLYQL------------TPISGVDVRFEGSNDYSVLKDADVIIDLLAINAKIMGQVGEAIKQYCPNAFVIITNPLDVMVYILREKCGLPPHVMGGHGDTMVPLIPLPELVKMGMISQQEVDDIVQRTRNGGGEIVSLL. 380
20 -9.330IDP95479 S-adenosylhomocysteinase Q5CPH1 [Cryptosporidium parvum]  ali follow..  17  270KIVVLGYGEVGKGCAQGLSGVGARVIVTEIDPICA------------------------LQASMEGYQVSVLEDVVSEADIFITATGNKDVITVEHMRKM----KENAYIANIGHF............................................................... 357
21 -9.330IDP06299 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae TIGR4] NP_344902 [Streptococcus pneumoniae TIGR4]  ali follow..  12  5NFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTED-------VIACHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQAL---------LPHLDKGDILIDGGNTFYKDTIRRNEELANS---GINFIGEKGALEGPSIMPG---QKEAYELVADVLEEISA....... 161
22 -9.270IDP02226 gene: yqjI; 6-phosphogluconate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA0164 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  19  5QIGVVGVGVMGKSLALNFESKGYSVALYDISKEKVDE-----------------TIEENRGKNLVGTHIVEEFVNSLESPRKILLMVNAGEITDKAIDSLVPHLDKGDILIDGGNTYFVDTIRRNKRLAEE--GINFIGEEGALKGPSIMPG---QKDAYEKVKDMLENISAK...... 162
23 -9.230IDP00498 putative glycosyl hydrolase YPO0166 [Yersinia pestis CO92]  ali follow..  15  5KITIIGGGSSYTPIQRIEQLPVTELALVDVEQGRQK--------VEIIAALTQRMLARHGLEQVKVSVHYSLDEAIRGARFVLTQF-ERLGLKYNLLGQ--ETTGIGGFAKALRTIPVMLDIAANVERPDAWI-INFTNPAGIVKIIGLCNVPISMHHMIAKLLQAPYE.......... 190
24 -9.230IDP92093 adenosylhomocysteinase, putative [Toxoplasma gondii ME49] TGME49_025050 [Toxoplasma gondii ME49]  ali follow..  22  256RVVICGFGDVGKGCAAAMKGAGARVVVTEVDPICA------------------------LQAAMEGYSVSTLESQLATADIFISATGNKDIITARHMSQM----KNNAIVGNIGHEVDMAGLLAWPGIQKVNI.............................................. 363
25 -9.190IDP02668 gene: gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA1526 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  14  3KITVVGAGSWGTALAMVLADNGHDVRIWGNRSELMDE-----------NTKHENSRYLPGITLPSTIVAYSSLEELVDVNVVLIVVPTKA---REVLQDMKKYVAGPTTWIHASKGIEPGTSKRISEVIEEEIPEDLIKDVVVLSAEEVGLRQATTVTSAAKRMEAAEEVQDL...... 168
26 -9.070IDP02362 gene: ldh; L-lactate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA1923 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  19  7RVVLVGTGAVGCSYAYCMINQAVEFVLVDVNEAKAEGEAMDLSHAVPFAPAPTRVWKG-------------SYEDCKDADLVVDLVEKNAKIFKQIVRSIMDSGFDGIFLATNPVDILTYVTWKESGLPERVIGS............................................ 146
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 4 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;