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Query: PF00290.20; TRPA_MAIZE/94-347; Tryptophan synthase alpha chain, from PfamA32U

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAALMAKGKTAFIPYITAGDPDLATTAEALRLLDGCGADVIELGVPCSDPYIDGPIIQASVARALASGTTMDAVLEMLREVTPELSCPVVLLSYYKPIMSRSLAEMKEAGVHGLIVPDLPYVAAHSLWSEAKNNNLELVLLTTPAIPEDRMKEITKASEGFVYLVSVNGVTGPRANVNPRVESLIQEVKKVTNKPVAVGFGISKPEHVKQIAQWGADGVIIGSAMVRQLGEAASPKQGLRRLEEYARGMKNALPLast
1 -13.800sp|Q96AT9|RPE_HUMAN Ribulose-phosphate 3-epimerase OS=Homo sapiens GN=RPE PE=1 SV=1  ali follow..  16  15.....................DLANLGAECLRMLDSGADYLHLDV-FVPNITFGHPVVESLRKQLGQDPFFDMHMMVSKP-------------------EQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGG--QKFMEDMMPKVHWLRTQPSLDIEVDGGVG-PDTVHKCAEAGANMIVSGSAIMR----SEDPRSVINLLRNVCSEAAQ... 222
2 -12.700sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   20  25VTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLS--------PHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFALTPNVTDIVSIARAAKEGGANGVTATNT----------------SGLMGLKSDGTPWPAVGIAKRTTYG--------GVSG-TAIRPIALRAVTSIARALPGFPILATGGIDSAESGLQFLHSGASVLQVCSAIQN---------QDFTVIEDYCTGLKALLY 239
3 -7.950sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   18  175VTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNL---------PHGMGERGMGLACGQDPELVRNICRWVRQAVQIPFFALTPNVTDIVSIARAAKEGGANGVTATN........................................................................................................................................ 286
4 -7.720sp|Q99707|METH_HUMAN Methionine synthase OS=Homo sapiens GN=MTR PE=1 SV=2  ali   10  76.ERCNVAGSRKFAKLIMAG--NYEEALCVAKVQVEMGAQVLDVNM---------------DDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAQATETDTKIRVCTRAPNDIIFDPNILTIGTGMEEHNLYAINFIHATKVIKET---LSFSFRGMEAIREA........................................... 293
5 -7.340sp|P16444|DPEP1_HUMAN(removed signalp:1-16) Dipeptidase 1 OS=Homo sapiens GN=DPEP1 PE=1 SV=3  ali follow..  13  109IRQAFREGKVASLIGVEGGHS-IDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLS-QRVVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNPDDVLRLVKQTDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGAVGFGGDF-DGVPRVPEGLEDVSKYPDLIAELLRRNWTEAEVKG------ALADNLLRVFEAVEQASNLTQAPEE.......... 349
6 -7.240sp|Q9UJM8|HAOX1_HUMAN Hydroxyacid oxidase 1 OS=Homo sapiens GN=HAO1 PE=1 SV=1  ali follow..  15  13.QHAKSVLPKSIYDYYRSGANDEETLADMLRNVAETDLSTSVLGQRVSMPICVGATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALRWLQLYIREVTKKLVRQAEKMGYKAIFVTDTPY----------RLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPS-EDIKWLRRLTSLPIVA--GILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEG...... 284
7 -7.160sp|Q6P1R4|DUS1L_HUMAN tRNA-dihydrouridine synthase 1-like OS=Homo sapiens GN=DUS1L PE=1 SV=1  ali follow..  19  70.....CPEDRPLIVQFCANDPE---VFVQAALLAQDYCDAIDLGCPQMIAKRGGAFLQD----------EWDLLQRMILLAHEKLSVPVTC-----------------------IRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKG------------------PLSGAAS-------EHIKAVRKAVAIPVFANGNIQCLQDVERCLRDGVQGVMSAEGNL............................ 236
8 -7.140sp|O95620|DUS4L_HUMAN tRNA-dihydrouridine synthase 4-like OS=Homo sapiens GN=DUS4L PE=2 SV=2  ali follow..  19  78.....NQGDCPLIVQFAANDARLLSDAARIVCPYANGID-INCGCPQR-------AMAEGYGACLIN--KPELVQDMVKQVRNQVETPGFSVSI--------------------IRIHDDLKRTVDLCQKAEATGVS--------------------------WITVHGRTAEERHQPVH--DSIKIIKENMSIPVIANGDIRSLKEAENVWRTGTDGVMVARGLL............................ 244
9 -7.070sp|Q9NX74|DUS2L_HUMAN tRNA-dihydrouridine synthase 2-like OS=Homo sapiens GN=DUS2L PE=1 SV=1  ali follow..  16  75..RTCEREQNRVVFQMGTSDAERALAVARLVENDVAGID-VNMGCPKQ-------STKGGMGAALLS--DPDKIEKILSTLVKGTRRPVTC-----------------------IRILPSLEDTLSLVKRIERTGIA--------------------------AIAVHGRKREERPQHPVSCEVIKAIADTLSIPVIANGGIQQYSDIEDFRQTAASSVMVARAAMWSIFLKEGLRPLEEVMQKYIRYAVQ... 273
10 -7.000sp|Q96G46|DUS3L_HUMAN tRNA-dihydrouridine synthase 3-like OS=Homo sapiens GN=DUS3L PE=1 SV=2  ali   15  1.........................................................................................................................................................LPELRDWGVALVTLHGRSREQRYTKLADWQYIEECQAASPMPLFGNGDILSFEDANRAMQTGVTGIMIARGLFTEIKEQRHWDISSSERLDILRD...... 102
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhang Y, Stec B, Godzik A. Between order and disorder in protein structures: analysis of "dual personality" fragments in proteins. Structure. 2007 Sep;15(9):1141-7.