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Query: PF00389.30; Q9KCG9_BACHD/20-325; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain, from PfamA32U

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst ILVSDAMSEQGLSPLLNDPRVECVQQNVADADDLHEYDALLVRSATTVTEELMEKMSSLKIIARAGVGVDNIDIDAATKHGIVVVNAPDGNTISTAEHTFAMICSLLRKIPQANASIKAGEWKRKAFQGTELRGKTLGIIGFGRIGSQIAKRAKAFEMTPYVFDPFLTKARAEKLGVTVASLDDVLQVADIITVHTPLTKETKGLLGMKNIGKTKKGVFLINCARGGIIDEEALKHYLREGHIAGAALDVFEEEPVADEELLAFDNVIATPHIAASTKEAQLNVAEQVSQEVLHFLEGNPVSNSINLast
1 -101.000sp|O43175|SERA_HUMAN D-3-phosphoglycerate dehydrogenase OS=Homo sapiens GN=PHGDH PE=1 SV=4  ali follow..  43  9VLISDSLDPCCRKILQDGGVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVN 317
2 -101.000sp|Q9UBQ7|GRHPR_HUMAN Glyoxylate reductase/hydroxypyruvate reductase OS=Homo sapiens GN=GRHPR PE=1 SV=1  ali follow..  27  9VFVTRRIPAEGRVALARAADCEVEQPAKELERGVAGAHGLLCLLSDHVDKRILDAAANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELK 327
3 -88.900sp|P56545|CTBP2_HUMAN C-terminal-binding protein 2 OS=Homo sapiens GN=CTBP2 PE=1 SV=1  ali follow..  33  36VALLDGRDTVEMPILKDLATVAFQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRN 355
4 -88.800sp|Q13363|CTBP1_HUMAN C-terminal-binding protein 1 OS=Homo sapiens GN=CTBP1 PE=1 SV=2  ali follow..  33  31ALLDGRDCTVEMPILKDVATVAFQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKN 349
5 -13.500sp|Q96HN2|SAHH3_HUMAN Putative adenosylhomocysteinase 3 OS=Homo sapiens GN=AHCYL2 PE=1 SV=1  ali   17  6.......................................MILDDGGDLTHWIYKKYPNMFIVEESVTGVHRLQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGL--------------KRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEI-ICALQACMDGFRLVKLNEVIRQVDIVIT----CTGNKNVVTREHLDRMKNSCIVCNMG.................................................................................. 179
6 -12.600sp|P23526|SAHH_HUMAN Adenosylhomocysteinase OS=Homo sapiens GN=AHCY PE=1 SV=4  ali follow..  16  127.......................................MILDDGGDLTNLIHTKYPQLLISEETTTGVHNLKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRA--------------TDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEI-INALQAAMEGYEVTTMDEACQEGNIFVT----TTGCIDIILGRHFEQMKDDAIVCNIGHFDVIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLA--NLGCAMGHPSFVMSNSFTNQVMAQIELWT............ 374
7 -12.200sp|O43865|SAHH2_HUMAN Putative adenosylhomocysteinase 2 OS=Homo sapiens GN=AHCYL1 PE=1 SV=2  ali follow..  16  225.......................................MILDDGGDLTHWVYKKYPNVFIVEESVTGVHRLQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRT--------------TDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEI-ICALQACMDGFRVVKLNEVIRQVDVVIT----CTGNKNVVTREHLDRMKNSCIVCNMG.................................................................................. 398
8 -11.500sp|Q96HN2|SAHH3_HUMAN Putative adenosylhomocysteinase 3 OS=Homo sapiens GN=AHCYL2 PE=1 SV=1  ali   18  156.......................................MILDDGGDLTHWIYKKYPNMFIVEESVTGVHRLYLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRT--------------TDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEI-ICALQACMDGFRLVKLNEVIRQVDI................................................................................................................... 300
9 -8.280sp|Q13423|NNTM_HUMAN NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens GN=NNT PE=1 SV=3  ali   11  1............................................................LISFIYPAQNPELLNKLSQRKTTVLAVPRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGLASAGAAKSMGAIVRGFDTYAKEMSKEFIEAEMKLFAQQCKEVDLISTALIPGKKAPVLFNKEMIESMKEGSVVVDLA-------------------AGGNFETTKPGELYIHKGITHIGYTDLP--SRMATQASTLYSNNITKLLKAISPDK....... 253
10 -7.170sp|Q687X5|STEA4_HUMAN Metalloreductase STEAP4 OS=Homo sapiens GN=STEAP4 PE=1 SV=1  ali follow..  14  20......................................................................................................................................ETVCIFGTGDFGRSLGLKMLQCGYSVVFGSRNPQKTTLLPSGAEVLSYSEAAKKSGIIIIAIHREHYDFLTELTEVLKILVDISNNLKINQYPESNAEYLAHLVPGAHVV-KAFNTISAWALQSGALDASRQVF----VCGNDSKAKQRVMDIVRN................ 172
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Godzik A., Rychlewski L. A support vector machine approach to the identification of phosphorylation sites. Cell Mol Biol Lett. 2005;10(1):73-89.