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Query: PF00834.19; RPE_SYNY3/6-205; Ribulose-phosphate 3 epimerase family, from PfamA32U

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst VVAPSILSADFSRLGEEIKAVDEAGADWIHVDVMDGRFVPNITIGPLIVDAIRPLTKKTLDVHLMIVEPEKYVEDFAKAGADIISVHVEHNASPHLHRTLCQIRELGKKAGAVLNPSTPLDFLEYVLPVCDLILIMSVNPGFGGQSFIPEVLPKIRALRQMCDERGLDPWIEVDGGLKPNNTWQVLEAGANAIVAGSAVFLast
1 -86.700sp|Q96AT9|RPE_HUMAN Ribulose-phosphate 3-epimerase OS=Homo sapiens GN=RPE PE=1 SV=1  ali follow..  40  7.IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATE--NPGALIKDIRENGMKVGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLR----TQFPSLDIEVDGGVGPDTVHKCAEAGANMIVSGSAIM 201
2 -9.650sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   15  37VIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLAICRWVRQAVQIPFFAKLTVTDIVSIARAAKEGGANGVTATNTVSGLMGLKSDGTPWPAVGIAK-------------------------RTTYGGVSGTAIRPIALRAVTSIARALP----GFPILATGGISAESGLQFLHSGASVLQVCSAIQ 220
3 -8.580sp|Q9NTM9|CUTC_HUMAN Copper homeostasis protein cutC homolog OS=Homo sapiens GN=CUTC PE=1 SV=1  ali follow..  11  36...............ESAVNAERGGADRIELGLSEGGTTPSMG----VLQVVKQSVQIPVEIEVMKAD----IRLAKLYGADGLVFGALTEDGHIDKELCMSLMAICRPLPVTFHRA--FDMVHDPMAALETLLTLGFE---SGCD--SSALEGLPLIKRLIEQAKGRIVVMPGGGITDRNLQRILEG............ 215
4 -8.340sp|P20839|IMDH1_HUMAN Inosine-5`-monophosphate dehydrogenase 1 OS=Homo sapiens GN=IMPDH1 PE=1 SV=2  ali follow..  16  260........................................................................LDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCG---QEVMACGRPQGTAVYKVAEARRFGVPIIADGGITVGHVVKALALGASTVMMGSLL. 390
5 -8.200sp|P36959|GMPR1_HUMAN GMP reductase 1 OS=Homo sapiens GN=GMPR PE=1 SV=1  ali follow..  18  115........................................................................SILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPG---RTKTGVGYPQLSAVIECADAHGLKGHIISDGGCTCPDVAKAFGAGADFVMLGGMF. 245
6 -8.020sp|P12268|IMDH2_HUMAN Inosine-5`-monophosphate dehydrogenase 2 OS=Homo sapiens GN=IMPDH2 PE=1 SV=2  ali follow..  15  260........................................................................LDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSG---QEVLACGRPQATAVYKVSEARRFGVPVIADGGINVGHIAKALALGASTVMMGSLL. 390
7 -7.930sp|Q9P2T1|GMPR2_HUMAN GMP reductase 2 OS=Homo sapiens GN=GMPR2 PE=1 SV=1  ali follow..  18  115........................................................................QILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPG---RKKTGVGYPQLSAVMECADAHGLKGHIISDGGCSCPDVAKAFGAGADFVMLGGML. 245
8 -7.800sp|Q15274|NADC_HUMAN(removed signalp:1-16) Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens GN=QPRT PE=1 SV=3  ali follow..  15  158......................................................................................HVVAAGG--VEKAVRAARQADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKP------------EELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGM... 255
9 -6.870sp|O94903|PROSC_HUMAN Proline synthase co-transcribed bacterial homolog protein OS=Homo sapiens GN=PROSC PE=1 SV=1  ali follow..  15  38.IQPRLVAVSKTKPADMVIEAYGHGQR---------------TFGENYVQELLEKASNPIKWHFIGHLQKQNVNKLMAVPADKVNSSWQRKGSPERLKVMVQINTSGEESKHGLPPSETIAIVEHINAKCPNL-LMTIGSGHDLSQGPNPDFQLLLSLREELCKKLNI-QVELSMGMSAD-FQHAVEVGSTNVRIGSTIF 247
10 -6.750sp|P11498|PYC_HUMAN Pyruvate carboxylase, mitochondrial OS=Homo sapiens GN=PC PE=1 SV=2  ali   16  119.........SLQYYMGLAEELVRAGTHILCIKDMAGLLKPTAC---MLVSSLRDFPDLPLHIHTHDTSGAGVAAMLAQAGADVVDVAAGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSECTATMKSGNSDVYENEIPGMGLGSKFKEVKKAYVEANQM....................................... 300
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.