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Query: PF01128.19; ISPD_ECOLI/8-229; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, from PfamA32U

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst VCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRLast
1 -77.400sp|A4D126|ISPD_HUMAN 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein OS=Homo sapiens GN=ISPD PE=3 SV=2  ali follow..  25  47VAAVLPAGGCGERMGVPTPKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVMKSIIQKYKRISLVEAGVTRHRSIFNGLKALAEPEVVIIHDAVRPFVEEGVLLKVVTAAKE-HGAAGAIRPLVSTVVSPSA-DGCLDYSLERARHRASEMPQAFLFDVIYEAYQQCSDYDLEFGTECLALKYCCTKAKLVEGSPDLWKVTYKRDLYAAESIIKE 279
2 -20.400sp|Q8NFW8|NEUA_HUMAN N-acylneuraminate cytidylyltransferase OS=Homo sapiens GN=CMAS PE=1 SV=2  ali follow..  11  45LAALILARGGSKGIPL---KNIKHLAGVPLIGWVLRAALDSGAFQSVWVSTDHDEIENVAKQFGAQRSSEVSKDSSTSLDAIIEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHEIQKGVREVTEPLNLNPAKRPRRQDWDGELENGSFYFAKRHLIEMGYLQGGKMAYYEM---------RAEHSVDIDVDIDWPIAEQRVLR 263
3 -14.400sp|Q9Y5P6|GMPPB_HUMAN Mannose-1-phosphate guanyltransferase beta OS=Homo sapiens GN=GMPPB PE=1 SV=2  ali follow..  17  1MKALILVGGYGTRLRLSTPKPLVDFCNKPILLHQVEALAAAG-VDHVILAVSYMSQVLEKEMKAQEQRLGI-LGTAGPLALARDLLSETADPFFVLNSDV----ICDFPFQAMVQFHRHHGQEGSILVPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILSPAVLQRIQLQPTSIEKEVFPIMAKEGQLYAMELQGFWMDIGQPKDFLTGMCLF.. 232
4 -13.700sp|Q13144|EI2BE_HUMAN Translation initiation factor eIF-2B subunit epsilon OS=Homo sapiens GN=EIF2B5 PE=1 SV=3  ali   12  43LQAVLVADSFDRRFFKDQPRVLLPLANVALIDYTLEFLTATG-VQETFVFCCWK----------AAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLV---YGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLQKTQGLRRFAFPLSLFQGSSDGVEVRY--DLLDCHISI.. 251
5 -13.600sp|Q9NR50|EI2BG_HUMAN Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens GN=EIF2B3 PE=1 SV=1  ali follow..  16  3FQAVVMAVGGGSRMTSSIPKPLLPVGNKPLIWYPLNLLERVG-FEEVIVVTTRDVQKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPTDVLVLSD----LITDVALHEVVDLFRAYDASLAMLM.............................................................................................. 132
6 -12.800sp|Q96IJ6|GMPPA_HUMAN Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens GN=GMPPA PE=1 SV=1  ali follow..  12  2LKAVILIGGKGTRFRFEVPKPLFPVAGVPMIQHHIEACAQVPGMQEILLIGFYQPDEPLTQFLEAAQQEFNLPGTGGGLYHFRDQILAGSPEAFFVLNADV---CSDFPLSAMLEAHRRQRHPFLLLGTTANRTQSLNY--CIVENPQTHEVLHYVEKPSTFISDIINCGI................................................... 183
7 -8.830sp|Q3KQV9|UAP1L_HUMAN UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 OS=Homo sapiens GN=UAP1L1 PE=2 SV=2  ali follow..  11  106VAVLLLAGGQGTRLGVTYPKGMYRVSRKTLYQLQAERIRRVEQLAGWYVMTSEFTLGPTAEFFREHNFF------------------HLDPANVVMFEQRLLPAVTFD---------------GKVILERKDKVAMAPDGNGGLYCALEDHKILEDMERRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPV............... 292
8 -8.680sp|Q16222|UAP1_HUMAN UDP-N-acetylhexosamine pyrophosphorylase OS=Homo sapiens GN=UAP1 PE=1 SV=3  ali follow..  11  103VAVLLLAGGQGTRLGVAYPKGMYDVGRKTLFQIQAERILKLQQVAEWYIMTSGRTMESTKEFFTKHKYF------------------GLKKENVIFFQQGMLPAMSFD---------------GKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEP................ 288
9 -8.530sp|Q16851|UGPA_HUMAN UTP--glucose-1-phosphate uridylyltransferase OS=Homo sapiens GN=UGP2 PE=1 SV=5  ali follow..  13  108LVVVKLNGGLGTSMGCKGPKSLIGVNENTFLDLTVQQIEHLNKTYNTDVPL-------------------VLMNSFNTDEDTKKILQKYNRVKIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYP---------PGHGDIYASFYNSGLLDTFIGEGKEYIFVSNI.................................................... 252
10 -7.010sp|Q9UBQ6|EXTL2_HUMAN(removed signalp:1-37) Exostosin-like 2 OS=Homo sapiens GN=EXTL2 PE=1 SV=1  ali follow..  8  29FTLIMQT----NRTD--------------LLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPVIFKQQTANRMRNRLQVFPELETNAVLMVDDDT--LISTPDLVFAFSVWQQFPDQIVGFVP-SSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDTQNCDDIAMNFIIAK....................... 217
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 2 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.