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Query: PF02424.15; C5BM31_TERTT/32-314; ApbE family, from PfamA32U

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGTEVSITFWHDDPAQAQQLLADGMAEMRRLDRELSPWIESSELATLNRLAAKAPQKISSEMLFLVDKSLYFSHLTHGAFDITFASVGWFYDYREKKQPSEAQRSALLPAINYRWLKLDKTAGTLAYAHDNVRIDLGGIAKGYAVDRVAQLLENAGVRNATISAGGDSQIVGDKRGKPWIIGIKNPRDGGKEEAEAAILLPLENTAISTSGDYERYFIDQKTGERVHHIINPRTGKSVEGVVSVTILGPRGSDTDPMSTSVFVLGVEKGLALVNSLANFECIILast
1 -6.840sp|Q17RS7|GEN_HUMAN Flap endonuclease GEN homolog 1 OS=Homo sapiens GN=GEN1 PE=2 SV=2  ali   12  3...........................VNDLWQILEPVKQHIPLRNLGGK------TIAVDLSLWVCEAQTVKKMMGSVMKPHLRNLFFVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSHFKSVLRECLHMLECLGIEAMCAYLNAGGHVDGCLTNDGDTFLYGAQT--------------------------YRNFTMNTKDPHVDCYTMSS--------IKSKLGLDRDALVGLAILLG----CDYLPKGVPGVGKEQALKLIQILKGQSLL. 235
2 -6.410sp|Q9UQ84|EXO1_HUMAN Exonuclease 1 OS=Homo sapiens GN=EXO1 PE=1 SV=2  ali   17  1................................................................................................................................................ADAQLAYLNKAGIVQAIITEDSDLLAFGCKK-----------------------------LKMDQFGNGLEIDQAR-----LGMCRQLGDVFTEEKFRYMCILSG----CD-YLSSLRGIGLAKACKVLRLANNPDIVK 102
3 -6.030sp|Q9UPR3|SMG5_HUMAN Protein SMG5 OS=Homo sapiens GN=SMG5 PE=1 SV=3  ali   12  1......................................................................................................................................................................................IGCKKPVSASGKEMDWAQMACHRCLVYLGDLSRYQNELAGVDTEALSVAPQIGMPFNQLGTLAGSKYYNVEA-CIQSEVSFEGAYGNLKRL.......... 105
4 -5.920sp|Q9UKB1|FBW1B_HUMAN F-box/WD repeat-containing protein 11 OS=Homo sapiens GN=FBXW11 PE=1 SV=1  ali follow..  9  261.....SIKIWDKTSLECLKVLTGHTGSVLCLERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSI----AVWDMASAT---DITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTC----EFVRTLNGHKRGIACLQYRDRLVVSGSSDNT-WDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAAL--DPRAPASTLCLRTLVE----HSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPS. 525
5 -5.830sp|Q969H0|FBXW7_HUMAN F-box/WD repeat-containing protein 7 OS=Homo sapiens GN=FBXW7 PE=1 SV=1  ali   6  81.....................DHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTL----KVWNA------ETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETG----QCLHVLMGHVAAVRCVQYDGRRVVSGAYDFM-WDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSI-----------RVWDVETGNCIHTLTGQSLTSGMELKDNILVSG....................... 297
6 -5.750sp|Q8NCI6|GLBL3_HUMAN(removed signalp:1-28) Beta-galactosidase-1-like protein 3 OS=Homo sapiens GN=GLB1L3 PE=2 SV=3  ali   12  3...............................ETMIGILNENNKDLHIPELRDCRYLRILVENQGRVNFSWQIQNEQKGITGSVSINNSSLEGFTIYSLEMKMSFFERLRSATWKPVPDSHQGPAFYCGTKDTFLSLLNWNYGF------------------------VFINGRNLGRYWNIGPQKPGVWLHPEDNEVILFEKMMSGSDIK......................................................................... 168
7 -5.650sp|Q495T6|MMEL1_HUMAN Membrane metallo-endopeptidase-like 1 OS=Homo sapiens GN=MMEL1 PE=1 SV=2  ali   12  66........................................QEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELEVILKVLENSTAKDRPAVEK-YRSCMNQSVIEKRGLLDILEVVGG------------WPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHYIDQPTLGMPSREYYFNGGSNRKVREAQFMVSVATLLREDANLPRDSCL....... 300
8 -5.480sp|O60341|KDM1A_HUMAN Lysine-specific histone demethylase 1A OS=Homo sapiens GN=KDM1A PE=1 SV=2  ali   12  1....................LPPPPPQAPPEEENESEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEAVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAA---ARQLQSFGMDVTLLEVGGRVATFRKGNGAMVVTGLGNPMAV------------SKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLG.................. 259
9 -5.440sp|Q9NY59|NSMA2_HUMAN(removed signalp:1-36) Sphingomyelin phosphodiesterase 3 OS=Homo sapiens GN=SMPD3 PE=1 SV=1  ali   15  5..........................................................................................................................SSSSAANPEELVAFDVVCGDFNFDNCSS--DKLEQQHSLFTHYRDPCRLGPGEEKPWAIGVCTPDNQKVLESEEGRREYLAFPTSKSSGQKGRKELLKGNGRRIDYMLHAEEGLCPDEVEEFSFITQLSGLTDHLPVAMRL.................... 160
10 -5.430sp|Q7Z4S6|KI21A_HUMAN Kinesin-like protein KIF21A OS=Homo sapiens GN=KIF21A PE=1 SV=2  ali   14  10..........................................................................IITGSKDHYI----KMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPN--HKDWVCALGVVPDHPVLLSGCRGGKVWNMDTFMPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGD................................................. 166
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;