current user: public |
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Query: PF11695.8; Q9A5F4_CAUVC/31-168; Domain of unknown function (DUF3291 topsan), from PfamA32U |
. 10 . 20 . 30 . 40 . 50 . 60 . 70 . 80 . 90 . 100 . 110 . 120 . 130 . | |||||||
# | Score | Template | Links and tools | %id | First | LAQVNVGRLKAPIDHPMIKDFADNLDRINALAEASPGFVWRLTGEGNNATDLAIDSDPLFIPNLSVWSDIPSLGAFVYRSGHVEIMRRRREWFEHMDLYMALWWVPAGHTPTVEEALEKLAHLEAHGPTPAAFTFKVP | Last |
1 | -10.100 | sp|Q7Z6G3|NECA2_HUMAN N-terminal EF-hand calcium-binding protein 2 OS=Homo sapiens GN=NECAB2 PE=1 SV=1 | ali follow.. | 7 | 283 | .MHLQLVRQEMAVCPEQLSEFLDSLRQYLRGTTGVRNCF---------HITAVRLSDGFTFVIYEFWETEEAWKRHLQSPLCKAFRHVKVDTLSQPEALSRIWCTVGRD............................. | 386 |
2 | -9.880 | sp|Q8N987|NECA1_HUMAN N-terminal EF-hand calcium-binding protein 1 OS=Homo sapiens GN=NECAB1 PE=1 SV=1 | ali follow.. | 11 | 249 | .SHIMLVQRQMSVIEEDLEEFQLALKHYVESASSQSGCL---------RISIQKLSNESRYMIYEFWENSSVWNSHLQTNYSKTFQRSNVDFLETPELTSTMWWI................................. | 348 |
3 | -7.550 | sp|O75037|KI21B_HUMAN Kinesin-like protein KIF21B OS=Homo sapiens GN=KIF21B PE=1 SV=2 | ali | 8 | 218 | ..............................................................VIKVW-NVDNFTPIGEIKGHDSPINAIC-----TNAKHIFTASSDCRVKLWNYVPGLTPCLPRRVLAIKGRATTLP | 287 |
4 | -7.520 | sp|Q96PN6|ADCYA_HUMAN Adenylate cyclase type 10 OS=Homo sapiens GN=ADCY10 PE=1 SV=3 | ali | 10 | 146 | LENLVAQNTTGPVFCPRLYHLMAYVCILMGDGQKCGLFLNTALRLSETQGNILE----------KCW-----------------LNMNKESWYSTSELKEDQWLQTILSLPSWEKI--VAGRVNIQDLQKNKFLMRAN | 254 |
5 | -7.190 | sp|Q9Y485|DMXL1_HUMAN DmX-like protein 1 OS=Homo sapiens GN=DMXL1 PE=1 SV=3 | ali | 15 | 225 | .................................................................AWVAEEELLNMLPAMQKDDP-----TWSELRAMGVGWWVRNTRILRKCIEKVAKAAFYRKNDPLDAAIFY... | 293 |
6 | -7.150 | sp|Q9HCH5|SYTL2_HUMAN Synaptotagmin-like protein 2 OS=Homo sapiens GN=SYTL2 PE=1 SV=3 | ali | 14 | 53 | ....DLPLLRGSHLNSFVKCTIDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGG-GTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK........ | 184 |
7 | -7.000 | sp|Q13546|RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 OS=Homo sapiens GN=RIPK1 PE=1 SV=3 | ali | 9 | 152 | IKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDI--WEANPEARPTFPGIEEKFRPFYLS............ | 291 |
8 | -6.990 | sp|O00507|USP9Y_HUMAN Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens GN=USP9Y PE=1 SV=2 | ali | 8 | 182 | LEIFRLKMILRLLQISSFNGKMNALNEINKVISSV--------SYYTHRHSNPEEEEWLTAERMAEWIQQNNILSIVLQDSQPQYVEKLEKILRTLQDLDNIWAAQAGKHEAIVKNV..................... | 300 |
9 | -6.970 | sp|Q9Y485|DMXL1_HUMAN DmX-like protein 1 OS=Homo sapiens GN=DMXL1 PE=1 SV=3 | ali | 19 | 217 | ..............................................................SVRMFEWGHSQQITCFRSGGNSRVTRMR--IVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVF... | 296 |
10 | -6.800 | sp|P11362|FGFR1_HUMAN(removed signalp:1-21) Basic fibroblast growth factor receptor 1 OS=Homo sapiens GN=FGFR1 PE=1 SV=3 | ali | 15 | 3 | LAARNV--LVTEDNVMKIADFARDIHHIDYYKKTTNGRL-KWMAPEALFDRIYTHQSDVWSFGVLLWEPVEELFKLLKEGHRMDKPSNCTN--ELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMP | 151 |
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9. Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018. Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7. |