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Query: PF00208.21; DHE3_ORYSJ/176-408; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase, from PfamA32U

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst GGSLGRDAATGRGVMYATEALLTEYSESISGSTFVIQGLGNVGSWAAKLIHQKGGKIVAVGDVTGAIRNKSGIDIPALLKHRSEGGSLEDFYGAEVMDAAELLVHECDVLVPCALGGVLNRENAAEVKARFIIEGANHPTDTEADEILAKKGVIVLPDIYANSGGVVVSYFEWVQNIQGFMWDEEKVNRELQKYMKNAFQNIKDMCKSQNCNLRMGAFTLGVNRVAKATLLRGLast
1 -79.1004xgi_A mol:protein length:436 Glutamate dehydrogenase  ali model follow..  41  201GGSLGRKEATGRGVFVVGCEAAKKKGVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVIAVQDHTGTIHQPAGVDTAKLLDHVGRTGGVAGFEGAEPMPNDEFWTVETEILIPAALENQITEKNASKIRTKIIVEGANGPTTTAADDILSANGVLVIPDVIANAGGVTVSYFEWVQDFSSFFWTEDEINHRLERVMREAFAGVWAVAEEHKVSVRTAAFIVACKRILMAREMRG 433
2 -78.6003aog_A mol:protein length:440 Glutamate dehydrogenase  ali model follow..  42  199GGSLGRRDATGRGVFITAAAAAEKIGLQVEGARVAIQGFGNVGNAAARAFHDHGARVVAVQDHTGTVYNEAGIDPYDLLRHVQEFGGVRGYPKAEPLPAADFWGLPVEFLVPAALEKQITEQNAWRIRARIVAEGANGPTTPAADDILLEKGVLVVPDVIANAGGVTVSYFEWVQDFNSYFWTEEEINARLERVLRNAFEAVWQVAQEKKIPLRTAAYVVAATRVLEARALRG 431
3 -77.0003k92_A mol:protein length:424 NAD-specific glutamate dehydrogenase  ali model follow..  38  191GGSQGRETATAQGVTICIEEAVKKKGIKLQNARIIIQGFGNAGSFLAKFMHDAGAKVIGISDANGGLYNPDGLDIPYLLDKRDSFGMVTNL-FTDVITNEELLEKDCDILVPAAISNQITAKNAHNIQASIVVERANGPTTIDATKILNERGVLLVPDILASAGGVTVSYFEWVQNNQGYYWSEEEVAEKLRSVMVSSFETIYQTAATHKVDMRLAAYMTGIRKSAEASRFRG 422
4 -77.0003k8z_A mol:protein length:423 NAD-specific glutamate dehydrogenase  ali model follow..  39  190GGSHGRESATAKGVTICIKEAAKKRGIDIKGARVVVQGFGNAGSYLAKFMHDAGAKVVGISDAYGGLYDPEGLDIDYLLDRRDSFGTVTKL-FNDTITNQELLELDCDILVPAAIENQITEENAHNIRAKIVVEAANGPTTLEGTKILSDRDILLVPDVLASAGGVTVSYFEWVQNNQGFYWSEEEVEEKLEKMMVKSFNNIYEMANNRRIDMRLAAYMVGVRKMAEASRFRG 421
5 -76.9002yfq_A mol:protein length:421 NAD-SPECIFIC GLUTAMATE DEHYDROGENASE  ali model follow..  35  182GGSEGRNEATGFGVAVVVRESAKRFGIKMEDAKIAVQGFGNVGTFTVKNIERQGGKVCAIAEWDYALYNENGIDFKELLAYKEANKTLIGFPGAERITDEEFWTKEYDIIVPAALENVITGERAKTINAKLVCEAANGPTTPEGDKVLTERGINLTPDILTNSGGVLVSYYEWVQNQYGYYWTEAEVEEKQEADMMKAIKGVFAVADEYNVTLREAVYMYAIKSIDVAMKLRG 419
6 -76.8001bvu_A mol:protein length:418 PROTEIN (GLUTAMATE DEHYDROGENASE)  ali model follow..  41  181GGIVARMDATARGASYTVREAAKALGMDLKGKTIAIQGYGNAGYYMAKIMSEEGMKVVAVSDTKGGIYNPDGLNADEVLAWKKKTGSVKDFPGATNITNEELLELEVDVLAPSAIEEVITKKNADNIKAKIVAELANGPTTPEADEILYEKGILIIPDFLCNAGGVTVSYFEWVQNITGDYWTVEETRAKLDKKMTKAFWDVYNTHKEKNINMRDAAYVVAVSRVYQAMKDRG 414
7 -76.6001b26_A mol:protein length:416 GLUTAMATE DEHYDROGENASE  ali model follow..  44  180GGSKGREEATGRGVKVCAGLAMDVLGIDPKKATVAVQGFGNVGQFAALLIQELGSKVVAVSDSRGGIYNPEGFDVEELIRYKKEHGTVVTYPKGERITNEELLELDVDILVPAALEGAIHAGNAERIKAKAVVEGANGPTTPEADEILSRRGILVVPDILANAGGVTVSYFEWVQDLQSFFWDLDQVRNALEKMMKGAFNDVMKVKEKYNVDMRTAAYILAIDRVAYATKKRG 413
8 -76.5001euz_A mol:protein length:419 GLUTAMATE DEHYDROGENASE  ali model follow..  42  182GGSLGRGTATAQGAIFTIREAAKALGIDLKGKKIAVQGYGNAGYYTAKLAKEQGMTVVAVSDSRGGIYNPDGLDPDEVLKWKREHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITEKNADNIKAKIVAEVANGPVTPEADDILREKGILQIPDFLCNAGGVTVSYFEWVQNINGYYWTEEEVREKLDKKMTKAFWEVYNTHKDKNIHMRDAAYVVAVSRVYQAMKDRG 415
9 -76.1003r3j_A mol:protein length:456 Glutamate dehydrogenase  ali model follow..  28  209GGSNIRAEATGYGVVYFAENVLKDLNDNLENKKCLVSGSGNVAQYLVEKLIEKGAIVLTMSDSNGYILEPNGFTKEQLNYIMDIKNNQKYSKTAKYFENQKPWNIPCDIAFPCATQNEINENDADQNKCKMIVEGANMPTHIKALHKLKQNNIILCPSKAANAGGVAVSGLEMSQNSMRLQWTHQETDMKLQNIMKSIYEQCHNTSKIYLSDLVAGANIAGFLKVADSFLEQG 454
10 -75.8001v9l_A mol:protein length:421 glutamate dehydrogenase  ali model follow..  36  180WGNPVREYATGFGVAVATREMAKKLWGGIEGKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDINGVAYRKEGLNVELIQKNKGLTGPALVELAEFVKNPDAIFKLDVDIFVPAAIENVIRGDNAGLVKARLVVEGANGPTTPEAERILYERGVVVVPDILANAGGVIMSYLEWVENLQWYIWDEEETRKRLENIMVNNVERVYKRWQREGWTMRDAAIVTALERIYNAMKIRG 419
11 -75.5003aoe_E mol:protein length:419 Glutamate dehydrogenase  ali model follow..  34  188GGSEGRDDAAGLGALLVLEALAKRRGLDLRGARVVVQGLGQVGAAVALHAERLGMRVVAVATSMGGMYAPEGLDVAEVLSAYEATGSL----PRLDLAPEEVFGLEAEVLVLAAREGALDGDRARQVQAQAVVEVANFGLNPEAEAYLLGKGALVVPDLLSGGGGLLASYLEWVQDLNMFFWSPEEVRERFETRVARVVDAVCRRAERGGLDLRMGALALALERLDEATRLRG 416
12 -75.3002bma_A mol:protein length:470 GLUTAMATE DEHYDROGENASE (NADP+)  ali model follow..  25  222GGSNLRVEATGYGLVYFVLEVLKSLNIPVEKQTAVVSGSGNVALYCVQKLLHLNVKVLTLSDSNGYVYEPNGFTHENLEFLIDLKEEKKGSSTAKYFPNEKPWGVPCTLAFPCATQNDVDLDQAKLLQKNGVGEGANMPSTVDAINLFKSNNIIYCPSKAANAGGVAISGLEMSQNFQFSHWTRETVDEKLKEIMRNIFIACSENALKNKYDLQAGANIAGFLKVAESYIEQG 468
13 -75.1005gud_A mol:protein length:471 Glutamate dehydrogenase  ali model follow..  31  219GGSLVRTEATGYGCVYFVSEMIKAKGESISGQKIIVSGSGNVATYAIEKAQELGATVIGFSDSSGWVHTPNGVDVAKLREIKEVRRARVSIEGATYHTDGSIWDLKCDIALPCATQNELNGENAKTLGCRFVAEGANMPSTPEAVEVFRERDIRFGPGKAANAGGVATSALEMQQNASRDSWSFEYTDERLQVIMKNIFKTCAETAAEYGNDYVVGANIAGFKKVADAMLAQG 461
14 -74.9001gtm_A mol:protein length:419 GLUTAMATE DEHYDROGENASE  ali model follow..  43  181GGSLGRIEATARGASYTIREAAKVLWDTLKGKTIAIQGYGNAGYYLAKIMSEDGMKVVAVSDSKGGIYNPDGLNADEVLKWKNEHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITKKNADNIKAKIVAEVANGPVTPEADEILFEKGILQIPDFLCNAGGVTVSYFEWVQNITGYYWTIEEVRERLDKKMTKAFYDVYNIAKEKNIHMRDAAYVVAVQRVYQAMLDRG 415
15 -74.4002yfh_A mol:protein length:448 GLUTAMATE DEHYDROGENASE, NAD-SPECIFIC GLUTAMATE DEHYDROGENASE, GLUTAMATE DEHYDROGENASE  ali model follow..  28  201GGSLIRPEATGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTKEKLARLIEIKASRDGRVGLVYLEGQQPWSLPVDIALPCATQNELDVDAAHQLIANGVKAVAEGATTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLGWKAEKVDARLHHIMTDIHDGSAAAAERYGLNLVAGANIVGFQKIADAMMAQG 445
16 -73.9001hwy_A mol:protein length:501 GLUTAMATE DEHYDROGENASE  ali model follow..  34  206GGIHGRISATGRGVFHGIENFIENMTPGFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESDGSIWNPDGIDPKELEDFKLQHGTILGF-PKAKIYEGSILEVDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPQADKIFLERNIMVIPDLYLNAGGVTVSYFQILKNLNHVSYGRLTVHSGLAYTMERSARQIMRTAMKYNLDLRTAAYVNAIEKVFRVYNEAG 497
17 -73.5004fcc_A mol:protein length:450 Glutamate dehydrogenase  ali model follow..  28  205GGSLIRPEATGYGLVYFTEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTKEKLARLIEIKSSRDGRFGLVYLEGQQPWSVPVDIALPCATQNELDVDAAHQLIANGVKAVAEGANTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLGWKAEKVDARLHHIMLDIHHACVEHGEGEQTNYVQGANIAGFVKVADAMLAQG 448
18 -73.5001aup_A mol:protein length:449 NAD-SPECIFIC GLUTAMATE DEHYDROGENASE  ali model follow..  29  200GGSLVRPEATGYGSVYYVEAVMKHENDTLVGKTVALAGFGNVAWGAAKKLAELGAKAVTLSGPDGYIYDPEGITTEEKINYMLEMRASGRKFGVQFFPGEKPWGQKVDIIMPCATQNDVDLEQAKKINVKYYIEVANMPTTNEALRLMQQPNMVVAPSKAVNAGGVLVVGFEMSQNSERLSWTAEEVDSKLHQVMTDIHDGSAAAAERYGLNLVAGANIVGFQKIADAMMAQG 446
19 -71.9001l1f_A mol:protein length:505 Glutamate Dehydrogenase 1  ali model follow..  37  210GGIHGRISATGRGVFHGIENFINEASPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAK-PYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTVHSGLAYTMERSARQIMRTAMKYNLDLRTAAYVNAIEKVFKVYNEAG 501
20 -70.5005xvi_A mol:protein length:460 Glutamate dehydrogenase  ali model follow..  30  188GGSLIRPEATGYGVVYYVEHMIAHATESFKGKRVAISGSGNVAQYAALKVIELGGSVVSLSDSQGSLIINGEGEIELIAQTKVERKQLASIVGAIAGARPWVHVGKVDVALPSATQNEISGEEAQVLGCKFIAEGSNMGCTQEAIDTFEAHAIWYAPGKAANAGGVAVSGLEMAQNSARLSWTSEEVDARLKDIMRDCFKNGLETAQEYATSLVTGSNIAGFTKVAAAMKDQG 457
21 -70.2006dhm_A mol:protein length:582 Glutamate dehydrogenase 1, mitochondrial  ali model follow..  36  287GGIHGRISATGRGVFHGIENFINEATPGFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESDGSIWNPDGIDPKELEDFKLQHGTILGF-PKAKIYEGSILEVDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTVHSGLAYTMERSARQIMRTAMKYNLDLRTAAYVNAIEKVFRVYNEAG 578
22 -69.5005k12_A mol:protein length:558 Glutamate dehydrogenase 1, mitochondrial  ali model follow..  36  263GGIHGRISATGRGVFHGIENFINEASPGFGDKTFVVQGFGNVGLHSMRYLHRFGAKCITVGESDGSIWNPDGIDPKELEDFKLQHGTILGF-PKAKIYEGSILEVDCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTVHSGLAYTMERSARQIMRTAMKYNLDLRTAAYVNAIEKVFRVYNEAG 554
23 -59.9001bw9_A mol:protein length:356 PHENYLALANINE DEHYDROGENASE  ali model follow..  25  145GGAGSSAFTTAVGVFEAMKATVAHRLGSLDGLTVLVQGLGAVGGSLASLAAEAGAQLLVADTDTERVAHAVALGHTAV-------------------ALEDVLSTPCDVFAPCAMGGVITTEVARTLDCSVVAGAANNVIADAASDILHARGILYAPDFVANAGGAIHLVGREVLG-----WSESVVHERAVA-IGDTLNQVFEISDNDGVTPDEAARTLAGRRAREASTTTA 354
24 -59.5001leh_A mol:protein length:364 LEUCINE DEHYDROGENASE  ali model follow..  25  141GSSGNPSPVTAYGVYRGMKAAAKEASDSLEGLAVSVQGLGNVAKALCKKLNTEGAKLVVTDVNKAAVSAAVAEE------------------GADAVAPNAIYGVTCDIFAPCALGAVLNDFTIPQLKAKVIAGSADNQLKPRHGKYLHELGIVYAPDYVINAGGVINVADELYG------YNRTRAMKRVDG-IYDSIEKIFAISKRDGVPSYVAADRMAEERIAKVAKARS 351
25 -59.3003vpx_A mol:protein length:364 Leucine dehydrogenase  ali model follow..  25  141GSSGNPSPVTAYGIYYGMKAAAKEADDSLAGKTVAVQGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAF------------------GATAVGINEIYSQEADIFAPCALGAIINDETIPQLKAKVIAGSANNQLKETRGDLIHEMGIVYAPDYVINSGGVINVADELDG------YNRERALKRVEG-IYDVIGKIFAISKRDNIPTYVAADRMAEERIARVANTRS 351
26 -56.5005b37_A mol:protein length:361 Tryptophan dehydrogenase  ali model follow..  24  140.GGPAPITSLGVFLGIKAAVESRWQSKRLDGMKVAVQGLGNVGKNLCRHLHEHDVQLFVSDVDPIKAEEVKRLF------------------GATVVEPTEIYSLDVDIFAPCALGGILNSHTIPFLQASIIAGAANNQLENEQSQMLAKKGILYSPDYVINAGGLINVYNEMIG------YDEEKAFKQVHN-IYDTLLAIFEIAKEQGVTTNDAARRLAEDRINNSKRSKS 348
27 -13.4003d4o_A mol:protein length:293 Dipicolinate synthase subunit A  ali model follow..  19  141................TIMMAIQHTDFTIHGANVAVLGLGRVGMSVARKFAALGAKVKVGARESDLLARIAEMGMEPF-----------------HISKAAQELRDVDVCINTIPALVVTANVLAEMPHTFVIDLASKPGGTD-FRYAEKRGIKALPGIVATAGRILADVL.............................................................. 285
28 -13.1002rir_A mol:protein length:300 Dipicolinate synthase, A chain  ali model follow..  17  143................TIMLAIQHTDYTIHGSQVAVLGLGRTGMTIARTFAALGANVKVGARSSAHLARITEMGLVPF-----------------HTDELKEHVKDIDICINTIPSMILNQTVLSSMTKTLILDLASRPGGTD-FKYAEKQGIKALPGIVATAGQILANVL.............................................................. 287
29 -12.7002hae_A mol:protein length:386 Malate oxidoreductase  ali model follow..  15  159.......QGTAVVVSAAFLNALKLTEKKIEEVKVVVNGIGAAGYNIVKFLLDLGVKNVVAVDRKGILNENDPETCLNEYHLEIARITNPERLSGDLETALE----GADFFIGVSRGNILKPEWIKKMSRKPVIFALANPVPREAGAFIVATGRSDHPNQVNNL-GAVEKRSKITKNML-------SAVEAIARSCEPEPERIIPEAFDMKVHLNVYTAV--------KGSAEG 380
30 -12.7004q39_A mol:protein length:260 PYLD, pyrrolysine synthase  ali model follow..  15  122.....NQPCTGIIYAEIASRYLK-----ADSKDVLVVGLGKVGFPGAEHLVQKDFRVYGYDADETLLERSNLGIIPFDPANPKKFSIIFEATPCANTIPEAVLSENC-VLSTPGIPCAISEELRDKYEVQLIAEPLGIGTASMLYSVL..................................................................................... 260
31 -12.1001vl6_A mol:protein length:388 malate oxidoreductase  ali model follow..  14  163.......QGTAVVVSAAFLNALKLTEKKIEEVKVVVNGIGAAGYNIVKFLLDLGVKNVVAVDRKGILNENDPETCLNEYHLEIARITNPERLSGDLETALE----GADFFIGVSRGNILKPEWIKKMSRKPVIFALANPVTGRSDHPNQVNNLLAFPGIMK---GAVEKRSKITKNM--------SAVEAIARSCEPEPERIIPEAFDMKVHLNVYTAVK............. 379
32 -11.6002a9f_A mol:protein length:398 putative malic enzyme ((S)-malate:NAD+ oxidoreductase (decarboxylating))  ali model follow..  16  165.......HGTAIVVLAAIFNSLKLLKKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDKFGIINEQE----AAQLAPHHLDIAKVTNREFKSGTLEDALE-GADIFIGVSAPGVLKAEWISKMAARPVIFAMANPIPEEAGAYIVGTGRSDFPNQINNV-GALDA-------------RAKTITVEMQIAAAKGIASLVPDDALSDAFKEGVAEIVAKSVRSVVLKSEG 392
33 -11.3005cee_A mol:protein length:413 NAD-dependent malic enzyme  ali model follow..  14  178.......HGTAIVVAAGILNALKVVKKSIEDVQVVINGAGSAGMAIAKMLLLLKVNNVVLVDKTGTLYKGVANLNEPQKKLVEVTNKYQEKGTLKEVLK------GKDIFIGVSAPGIVTAEMVATMAKDAIVFALANPVPEIMPDEAKKNNCLAFPGVFR---GTLDAKATQITE--EMKKAATYALKNIIKEQDLNENNILPTSFNKEVVKQIAL------AVCKVAKETG 403
34 -10.8001ww8_A mol:protein length:439 malate oxidoreductase  ali model follow..  14  163.......QGTAAVVLAGLLNALKVVGKKISEITLALFGAGAAGFATLRILTEAGVK-VELVNGKPRILTSDL-DLEKLFPYRGWLLKKTNGENIEGGPQEALKDADVLISFTRPGPGVIKPQWIEKMNEDAIVFPLANPVPEILPEEAKKNNLLGFPGIFR---GALDV-------------RARTITDSMIIAAAKAIASIVEEPSEENIIPSPLNPIVYARAVAEEAMKEG 396
35 -10.2005hm8_A mol:protein length:498 Adenosylhomocysteinase  ali model follow..  15  257................LLHGLFNGCIQMLAGKKIVVLGYGEVGKGCAQGLSGVGARVI-------------------VTEIDPICALQASMEGYQVSVLEDVVSEADIFITATGNKDVITVEHMRKMKENAYIANIGH............................................................................................... 359
36 -10.1003dfz_A mol:protein length:223 Precorrin-2 dehydrogenase  ali model follow..  12  18...........................DLKGRSVLVVGGGTIATRRIKGFLQEGAAITVVAP-----------TVSAEINEWEAKGQLR----RKKVGEEDL--LNVFFIVVATNDQAVNKFVKQHIKNDQLVNMASSF----------SDGNIQIPAQF-SRGRLSLA----ISTDGASPLLTKRIKEDLSSNYDESYTQYTQFLYECRVLIHRLNVSKSRKH......... 184
37 -10.1004xdz_A mol:protein length:343 Ketol-acid reductoisomerase  ali model follow..  11  15............................IKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDRAIDDGFKPMYTKDAVAI----------------------ADIIVFLVQKSLWLNSVKDFMKKGADLVFAHGFNIHFKIIEPPKD-YMIAPRSYEMGGGVPALVAVYQNVSGEALQKALAIAKGIGCARAGVIESTFKEETETDLVILVGGIMELIKASFETLVEEG 218
38 -10.1004tsk_A mol:protein length:350 Ketol-acid reductoisomerase  ali model follow..  18  15............................LADKRIAVIGYGSQGHAHAQNLRDSGFDVVIGPGSSWAKAEADGFRVMAVGEAVEE----------------------SDVIMDERQPAVYEREIRPYLTAGKALAFAHG............................................................................................... 108
39 -9.9903dtt_A mol:protein length:245 NADP oxidoreductase  ali model follow..  17  7........................ENLYFQGMKIAVLGTGTVGRTMAGALADLGHEVTIGTKATLARAEPDAMGAPPFSQWLPEHPHVHLAAFADVAAGAELV-----NATEASSIAALTAAGAENLAGKILVDIAN................................................................................................ 119
40 -9.9505bqf_A mol:protein length:322 NADP-dependent 2-hydroxyacid dehydrogenase  ali model follow..  15  139...........................EAAEVTVGVMGLGILGQDAVAKLKVMGFNVIGWSRTRKTIEGVETFDAGELDRFLAK----------------------TDILVGLL----LTPETTGFYDSELFKKLRRDGALGQPVFINAGRGKSQIETDIVSAGTLGGASLDVFEVTDSPLWELENV.............................................. 280
41 -9.9202dld_A mol:protein length:337 D-LACTATE DEHYDROGENASE  ali model follow..  12  140........................IGREVRDQVVGVVGTGHIGQVFMRIMEGFGAKVIAYDIFKNPELEKKGYYVDSLDDL---------------YKQADVISLHVPDV---ANVHMINDKSIAEMKGVVIVNCSRGRLVDTDARGLDSGKI----------FGFVMDTYEDEVGVFNKDWEGKEFPDKRLADLIDRPNVLV--TPHTAFYTTHAVRNMVVKAFNNNLK... 319
42 -9.9004weq_A mol:protein length:341 NAD-dependent dehydrogenase  ali model follow..  16  152...........................EAADVTVGIMGMGVLGQDAARKLAAMGFKVIGWSRSKRVIEGVETYDAAGLDAFLGR----------------------TDFLVGLL----LTPDTRGIFNAALFAKLSRNGPFGAPVFINAGRGGSQVEADILECGVLGGASLDVFERPESRFWDMPNV.............................................. 293
43 -9.8901j49_A mol:protein length:333 D-LACTATE DEHYDROGENASE  ali model follow..  12  140........................IGREVRDQVVGVVGTGHIGQVFMQIMEGFGAKVITYDIFRNPELEKKGYYVDSLDDL---------------YKQADVISLHVPDV---ANVHMINDESIAKMKDVVIVNVSRGPLVDTDARGLDSGKI----------FGYAMDVYEGEVGIFNEDWEGKEFPDARLADLIARPNVLV--TPHTAFYTTHAVRNMVVKAFDNNLE... 319
44 -9.8305yeq_A mol:protein length:340 Ketol-acid reductoisomerase (NADP(+))  ali model follow..  11  15............................IKEKRVAVLGYGSQGRAWALNLRDSGIKVSVGLEREGKQAENDGFKPLRTEEAVR----------------------NSDIIIDMIQRTVYLERVKPYLKEGMDLVFAHG-FNIHYRLIEPPSNVDVY-EYFAKGGGVPALVATYQDHSGKALQKALAVAKAIGATRAGVIETTFKEETETDLVDLVGGVMQLMRYAFQTLVEAG 218
45 -9.8204cuj_A mol:protein length:338 D-LACTATE DEHYDROGENASE  ali model follow..  11  138........................TGFTMHGKTAGVIGTGKIGVAALRILKGFGMRLLAFDPYPSTAALDLGVEYVDLQTL---------------FAESDVISLHCPLT---ENYHLLNHAAFDQMKGVMIINTSRGALIDSQAEALKNQKI----------GSLGMDVYENERDLFFEDKSVDVIQDDVFRRLSACHNVLF--TGHQAFLTAEALISISETTLQNLSQ... 317
46 -9.7803nv9_A mol:protein length:487 Malic enzyme  ali model follow..  14  196.......QGTASVTLAGLLNALKLVKKDIHECRMVFIGAGSSNTTCLRLIVTAGAD-IVMFDSKGSLHNGREDIKKDTRFYRKWEICETTNPSKFGSIAEACVGADVLISLSTPGPGVVKAEWIKSMGEKPIVFCCANPVPEEAGAYIVATGRGDFPNQVNNS-GALIVRARKITD--NMAIAASRALAEFAEKRGINPDNIIGTMDEPGIFPKEAA------DVAMQAIKDG 429
47 -9.6505w3k_A mol:protein length:340 Ketol-acid reductoisomerase (NADP(+))  ali model follow..  11  15............................LQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGGVIQPPADVDVFLPKGPGHLVRRTFVEGSAVPSLFG-----IQQDASGQARNIALSYAKGIGATRAGVIETTFK-EETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLH--EMKLIVDLMYEGG 242
48 -9.6302ziz_A mol:protein length:495 Adenosylhomocysteinase  ali model follow..  12  261................LIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSE-LLNFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTK........................ 471
49 -9.5905gz1_A mol:protein length:326 Meso-diaminopimelate D-dehydrogenase  ali model follow..  17  1............................MSKIRIGIVGYGNLGRGVEAAIQQNDMELVAVFTRR-----------------DPKTVAVKSNVKVLHVDDAQSYKDEIDVMILCGGSATDLPEQGPYFAQNTIDSFDTHARIPDYFDAVEQSGKVAIISVGWDPG..................................................................... 126
50 -9.5703wwz_A mol:protein length:345 D-lactate dehydrogenase (Fermentative)  ali model follow..  12  148........................TGFDLHGKRVGVIGTGQIGETFARIMAGFGCELLAYDPYPNPRIQALGGRYLALDAL---------------LAESDIVSLHCPLT---DTRHLIDAQRLATMKGAMLINTGRGALVNAAAEALKSGQL----------GYLGLDVYEEEADIFFEDRSDQPLQDDVLARLLSFPNVVVT............................. 303
51 -9.5603wx0_A mol:protein length:345 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding  ali model follow..  11  148........................TGFTMYGKTAGVIGTGKIGVAMLRILKGFGMRLLAFDPYPSAAALELGVEYVDLPTL---------------FSESDVISLHCPLT---ENYHLLNEAAFDQMKGVMIVNTSRGALIDSQAEALKNQKI----------GSLGMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLF--TGHQAFLTAEALTSISQTTLQNLSN... 327
52 -9.5603wyb_A mol:protein length:334 Meso-diaminopimelate D-dehydrogenase  ali model follow..  19  1............................MSKIRIGIVGYGNLGRGVEAAIQQNDMELVAVFTRR-----------------DPKTVAVKSNVKVLHVDDAQSYKDEIDVMILCGGSATDLPEQGPYFAQNTIDSFDTHARIPDYFDAVNA---------AAEQSGKVAI................................................................ 118
53 -9.4705tx7_A mol:protein length:327 D-isomer specific 2-hydroxyacid dehydrogenase family protein  ali model follow..  14  145...........................ELTGKTMGIVGFGNTGRRVGRIANALGMNVIAYAPRSRFDPDYRPFEHVGLDELFTSADVVSTPETEGLVDARRLASMRPGYLINTARGPLLDERAAEALDSGRLAGAGLDVLSQEDNPLLSAKNCLITP---------------------HLAWASRTARRTLMDSTAANIRSFIEGTPVNVVN..................... 319
54 -9.4303wgo_A mol:protein length:326 Meso-diaminopimelate dehydrogenase  ali model follow..  20  2............................NSKIRIGIVGYGNIGKGVEKAIKQN-----------------DDMELEAIFTRRDINKVDSNNSKLVHISRLELYKDTVDVMILCGGSATDLVEQGPMIASNTVDSFDNHGRIPQHFERMKKAGNISLISTGWDPG..................................................................... 126
55 -9.4103ond_A mol:protein length:488 Adenosylhomocysteinase  ali model follow..  14  251................LPDGLMRATDVMIAGKVAVVAGYGDVGKGCAAALKQAGARVI-------------------VTEIDPICALQATMEGLQVLTLEDVVSEADIFVTTTGNKDIIMLDHMKKMKNNAIVCNIGHFDNEIDMLGLETHP................................................................................. 367
56 -9.3901qp8_A mol:protein length:303 FORMATE DEHYDROGENASE  ali model follow..  16  121...........................LIQGEKVAVLGLGEIGTRVGKILAALGAQVRGFSRTPKEGPWRFTNSLEEALREARAAVCALPLNKHTRVKYQHLALMAEDVFVNVGRAEVLDRDGLRILKERPQFIFAGRNDFAKDAEFFSLPNVVATPWVAGGY...................................................................... 265
57 -9.3902dc1_A mol:protein length:236 L-aspartate dehydrogenase  ali model follow..  17  1...............................MLVGLIGYGAIGKFLAEWLERNGFEIAAILDVRGE-------------------------HEKMVRGIDEFLQREMDVAVEAASQQAVKDEKILKAGIDLIVLSADRDFLSRVREVCRKTGRRVYIASGAIGGLDAIFSASELIEEIVLTTRKNWRQFGRKGVIFEGSASEAAQKFPKNLNVAATLSIASGKDV........ 175
58 -9.3604zgs_A mol:protein length:386 Putative D-lactate dehydrogenase  ali model follow..  16  172........................VGVEMRHKVVGVVGTGAIGQQAARILKGIGCKVFAYDIKPNPAVEAMGIPYVSLDEL---------------LAMSDIVTLHCPLL---STRQLINKESIQKMKGVMLINVSRGGLIDSAADALESGQI----------GALGLDVYE............................................................. 295
59 -9.3603kb6_A mol:protein length:334 D-lactate dehydrogenase  ali model follow..  13  135........................LARELNRLTLGVIGTGRIGSRVAMYGLAFGMKVLCYDVVKREDLKEKGCVYTSLDEL---------------LKESDVISLHVPYT---ETHHMINEERISLMKGVYLINTARGKVVDTDARAYQRGKF----------SGLGLDVFEDEEILILKKYTEGKATDKNLKILELACKDNVIITPHIAYYTDKSLERIREETVKVVKA... 316
60 -9.3505v96_A mol:protein length:480 S-adenosyl-l-homocysteine Hydrolase  ali model follow..  18  242................LLDGLNRATDVMLAGKECVICGFGDVGKGCAEALKGQGARVIVTE-----------IDPINALQACMA--------GYTVKTVEDCLATADIYVTATGNKDIITLDHMKKMKDMAIICNIGHFDNEIDVLGLKTC.................................................................................. 357
61 -9.2303n58_A mol:protein length:464 Adenosylhomocysteinase  ali model follow..  10  233................LVDGIRRGTDVMMAGKVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQADGFEVVTLDDAASTADIVVTTTGNKDVITIDHMRKMKDVGNIGHFDNEIQVAALRNLKWTNVKPQVDLIEFPDGKRLLLSEGRLLHPSFVMSATNQVLGQIELFTRTDAYKNEVYVLPKHLDEKVARLHLDKLGAK--TVLSEEQAAYI.............. 449
62 -9.1804xdy_A mol:protein length:338 Ketol-acid reductoisomerase  ali model follow..  10  14............................LRDKTIAVMGYGAQGDAQANCLKDSGINVVIGKNPSWEKAKEDGFEVLPIDKAAEK----------------------GDVVHILVQPAIYENQIKPQLKAGKALCFSHG-FNICFKRIVPPEDVDVI-KAYLEGFGVPGLVAVKQNPSGEAREVALAMTKAMHWTKAGILECTFEQETYEDLCVLCGGLVELMRNGFEVLVEAG 222
63 -9.1703wwy_A mol:protein length:358 D-lactate dehydrogenase  ali model follow..  16  157........................MGIDLYEKTAGIIGTGKIGQILIKILRGFDMKVIAYD--------------------LFPNQKVADELGFEYVSLDELYA-NSDIICPLDTKYMINRRSMLKMKGVILVNTGRGMLIDSADEALKDKKI----------GAVALDVYEEEENYFFEDKSTQVIEDDILGRLLSFYNVLI--TSHQAYFTKEAVGAITVTTLNNIKD... 337
64 -9.1703d64_A mol:protein length:494 Adenosylhomocysteinase  ali model follow..  10  257................LVDGIKRATDVMIAGKIAVVAGYGDVGKGCAQSLRGLGATVWVTEIDPICALQAEGYRVVTMEYAADKADIFVTATGNYHVINHDHMKAMRHVCNIGHFDSEIDVASTRQYQWENIKPQVDHIIFPDGKRVLLAEGRLVHPSFVMSNTNQTLAQIELFTRGGEYANKVYVLPKHLDEKVARLHLARIGAQLS-ELSDDQAAYI.............. 473
65 -9.1501zfn_A mol:protein length:253 Adenylyltransferase thiF  ali model follow..  16  1.GSMNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLADDD--------VHLSNLQRQILFTTEDIDRPKSQVSQ-QRLTQLNPDIQL--ALQQRLTGEALKDARADVVLDCTNMATRQEINAACVALNTPLITASAVGFGGQLMVL............................................................... 163
66 -9.1303x2e_A mol:protein length:411 Adenosylhomocysteinase  ali model follow..  9  183................TWDAIMRNTNLLVAGKNVVVAGYGWCGRGIALRAAGLGARVIVTEVDPVKAVEADGFTVMPMKEAVKIADFVITASGNTDVLSKEDILSLKDGAVLANAGHFNVEIPVRVLEEIAVEKFEARPNVTGYTLENGKTVFLLAEGRLVNFALQIFAVLYLLENHRKMSPKVYMLPDEIDERVARMKLDSLGVKIDE-LTEKQRRYLRSWQ.......... 405
67 -9.0701v8b_A mol:protein length:479 adenosylhomocysteinase  ali model follow..  18  243................LPDGLMRATDFLISGKIVVICGYGDVGKGCASSMKGLGARVYITEIDPICAIQAEGFNVVTLDEIVDKGDFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHFDDEIQVNELFNYKGIHIENVKPQVDRITLPNGNKIIVL------ARGRLLNL............................................................... 392
68 -9.0502raf_A mol:protein length:209 Putative Dinucleotide-Binding Oxidoreductase  ali model follow..  19  8.........................NLYFQGMEITIFGKGNMGQAIGHNFEIAGHEVTYYGSKDQATTLGEIV-----------------------------------MAVPYPALAALAKQYATQLKGKIVVDITN................................................................................................ 85
69 -9.0404s1v_D mol:protein length:332 D-3-phosphoglycerate dehydrogenase-related protein  ali model follow..  17  141........................LGRTLSGRTLGIWGLGKIGQRIAQFGHVFGMPILVWGSESRQKALELGYQAAADKAEFFAKADVLSLHLRLNDATRGIVTKQ--LFVNTSRAELVESGAYSVMQANPMRQAANEPALPNNEPLLSLPNVLCAPHL.......................................................................... 289
70 -9.0403h9u_A mol:protein length:436 Adenosylhomocysteinase  ali model follow..  14  197................LVDGIKRATDVMIAGKTACVCGYGDVGKGCAAALRGFGARVV-------------------VTEVDPINALQAAMEGYQVLLVEDVVEEAHIFVTTTGNDDIITSEHFPRMRDDAIVCNIGH............................................................................................... 299
71 -9.0306aph_A mol:protein length:445 Adenosylhomocysteinase  ali model follow..  17  206................AVDAIRRATDVMLAGKRVVVCGFGDVGKGTAASFRGAGSIVT-------------------VTEIDPICALQAAMEGYEVKQLDTVVDNADIIITTTGNFGIVRGEHFEKMKDKTIVCNIGH............................................................................................... 308
72 -9.0201xdw_A mol:protein length:331 NAD+-dependent (R)-2-Hydroxyglutarate Dehydrogenase  ali model follow..  13  140........................FSKEVRNCTVGVVGLGRIGRVAAQIFHGMGATVIGEDVFEIKGIED----------------------YCTQVSLDEVLE-KSDIIAPYENGAVVTRDFLKKMKGAILVNCARGQLVDTEAEAVESGKL----------GGYGCDVLDGEASVFGKDLEGQKLENPLFEKLVDLYPRVL-ITPHLGSYTDEAVKNMVEVSYQNLKD... 319
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Godzik A., Rychlewski L. A support vector machine approach to the identification of phosphorylation sites. Cell Mol Biol Lett. 2005;10(1):73-89.