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Query: PF00150.18; MANB_CALSA/46-292; Cellulase (glycosyl hydrolase family 5), from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst VKIDTSTLIGTNHAHCWYRDRLDTALRGIRSWGMNSVRVVLSNGYRWTKIPASEVANIISLSRSLGFKAIILEVHDTTGYGEDGAACSLAQAVEYWKEIKSVLDGNEDFVIINIGNEPYGNNNYQNWVNDTKNAIKALRDAGFKHTIMVDAPNWGQDWSNTMRDNAQSIMEADPLRNLVFSIHMYGVYNTASKVEEYIKSFVDKGLPLVIGEFGHQHTDGDPDEEAIVRYAKQYKIGLFSWSWCGNSLast
1 -96.000PF00150.18; MANB_CALSA/46-292; Cellulase (glycosyl hydrolase family 5)  ali  100  1VKIDTSTLIGTNHAHCWYRDRLDTALRGIRSWGMNSVRVVLSNGYRWTKIPASEVANIISLSRSLGFKAIILEVHDTTGYGEDGAACSLAQAVEYWKEIKSVLDGNEDFVIINIGNEPYGNNNYQNWVNDTKNAIKALRDAGFKHTIMVDAPNWGQDWSNTMRDNAQSIMEADPLRNLVFSIHMYGVYNTASKVEEYIKSFVDKGLPLVIGEFGHQHTDGDPDEEAIVRYAKQYKIGLFSWSWCGNS 247
2 -35.500PF12876.7; W0IW86_9BACT/13-359; Sugar-binding cellulase-like  ali follow..  13  22......................DKALDGLVERGYDAVRIDAYPHLVAADRVMPALTEFICKCRERGLRVALSTWFQNDTTERRLGIASARVHAAIWIATIERAGLLDAVLYVDICNEWPNDWRTPASFDWMRECCRLLRERYPALPLTTSFSTFLS---------GEDLRDANPDFLDFLEPHRWMSFATARELDALVDWSRATGKPLVTTEGWAIVDYKDWPVKELNAWAVERVVASGRWAAICTS 322
3 -26.900PF03198.14; GAS5_YEAST/19-331; Glucanosyltransferase  ali follow..  14  23ESGERFYIRGVDYQ---DASVCDRDVPVLKDLGINTVRV-------YTVDNSQDHSHCMKLLQENGIYLILVNTPTSAISRYDPACSYNADYLQNVFATIDTFADYDNVLGFFAGNEVINSVNTTNTATYVKAVVRDMKKARKYRQIPVGYSAADIVANRQLAAEYFNCGDEADARIDMFGVNDYESSFVVSGYSTKMKLYQDYSVPVFLSEFGCNQVKSSRPFTEIEAIYSTQMSGGLVYEYSNE. 282
4 -20.900PF02836.17; Q5M3K5_STRT2/324-637; Glycosyl hydrolases family 2, TIM barrel domain  ali follow..  11  10LNGKRIVFKGVNTGRCITEEDMLWDIKVMKQHNINAVRTSHYPNQ----------TRWYELCDEYGLYVI-LETHGTWQKLGASEPEWLPACLDRANNMFQRDKNHASVIIWSCGNESYAGKD-------IADMADYFRSVDNTRPVHYEGVAWCREFDYITDIESRMYAKPADIEEYLTTGKLVDLSSVSDKHFASGNLTNKPQKPYISCEYMHTMGNSGGGLQLYTDLEKYPEYGGFIWDFIDQA 259
5 -19.400PF14488.6; D4IPL3_9BACT/51-219; Domain of unknown function (DUF4434 topsan)  ali follow..  9  1IRATFLDEVSWDIPHQNWGVKEDADFKAMKQMGINTVVLIRARTGKVKYPPVDLVEMFLALSDKYGMDFWFGTYDSCYHWHVGEYEKEIELNMQLIDEVWAKYGHHKSFRGWYLSQEI--SRRTRNVSKIYAAMGRHAKEISGGLKTMISP................................................................................................ 164
6 -19.300PF07745.13; Q9KBA5_BACHD/222-585; Glycosyl hydrolase family 53  ali follow..  11  1MKGVDIALEQSGVTFYDDHGNVQDIFQTLQEAGVNYIRIRIWNDYGGGNNDLEKAIEIGKRATKNGM--VLANFHYSDFWADPAKQKPKQALYEFTKESVKTMLDEGIDIMVQVGNETTNAFNWEKMSELFNEGSRAVREVDETILVALHFTN-PETPGRYETIAQRLYEYNVDYDVFASSYYPFWHGTLNNLTTVLSHVADTYDKLVMVAETSQGQGTAVRDVIEAVVNVGKSGMGVFYWE..... 297
7 -15.000PF01229.17; IDUA_MOUSE/13-533; Glycosyl hydrolases family 39  ali follow..  11  53.......................AYIGAVPHSGIEQVRI-RKSPGQGLMYNFTHLDAFLDLLMENQLLPGFLMGSPSGYFTDFDDKQQVFEWKDLVSLLARRYIGHVSKWNFETWNEPD-SMTTQGFLNYYDACSEGLRIASPT--LKLGGPG-SPMCWSLLGHCANGTNFFTGEVGVYISLHKKGAGSSIAILEQEMAVVEQ............................................ 260
8 -14.800PF02449.15; Q5WC61_BACSK/18-400; Beta-galactosidase  ali follow..  8  15......................EEDFRLMPLAHCNTFSINIFGWSAIEPEEFAWLDDIMDRLAEKGYHAILRNLHGQRHNHCLTSPVYRQKVKQINRKLAERYKGHPALKMWHISNEYGGACHCDYCQDAFRAWLKRRYDNRLDKL---WTGFWSHTYTDWEQIESPAPHGESMIHGHNLDWKRFVTDQTIDFYRNEIEPLRELTIKITTNFMGNYPHMRPFLGLNYRKFADELDV........... 261
9 -13.300PF14587.6; C6XV55_PEDHD/39-400; O-Glycosyl hydrolase family 30  ali follow..  11  14......TIHSFGASDCWSAKYVGKWSDL-KGIGLSLWRFNIGSGSYEQGAESNIPDEFLKAAKQRGVAYTLGFSLTPPAFMSGNGKAYKAGMTNAYAAFMSAVSAHFKFDFLSPVNEPQWFATNAEIADLVKVLSVQLPSKSPGTQVVIGEAG-GDQISEFFSPASAHYIADRPNVKRIISGHSYFTTCPDNNLIHVREQVAAKLLEVWQTEFGILGNICNQYNGGPRNTGIDYGLSWQWWLSISPY 354
10 -12.600PF12891.7; B8I5Z5_CLOCE/86-317; Glycoside hydrolase family 44  ali follow..  9  32....................................................VVITDFHDKNLAAGEPYSLVTLKDAPLSLTPDTTDNYVYMDELVNLLVNKYGSASTIKGYAIDNEPANNATCAEVIDKNINLAKTVKGVDPSAETFGLVAYGFAAYNDFQSATDWKDLKGNYTWFLALDLHWYPEA........................................................... 232
11 -12.400PF11790.8; Q7S276_NEUCR/147-396; Glycosyl hydrolase catalytic core  ali follow..  11  14.........DLTWYYNY-KPLPSQIYSNVSQSDFEFVPMLWGAPSDISDKSFYNTIKTLIDDRGVNVTHILTFNEPDGPGQYGGSDIDPEVAAQVWVNNIVPLQEDY----------------------------KALRVGLPACTGAPAGMEWTQKFLEACSGLISEDEKTKNCTFDFVPIHWYG--NFEGLASHMGEYSAAFNKSMWITEYNLANANLQETYTTSAEYLDRLDVERYSL...... 219
12 -12.300PF13204.6; T0JWN0_COLGC/37-419; Protein of unknown function (DUF4038 topsan)  ali follow..  9  10.TGRPFFWIADTLFHKLNKTDVDIYLTDRAAKGFNVIQAVVLSKTQPNLQYFEHVDWIVTRAAEYGILICFVPTWGRYVNWGWYKLFDKDTAEWFGRFLGNRYPGIPKMMGGD--SDPKSEDTRSIWAAMMRGFMEEEAKKGYDAFVTFQPTSPWIADPPTPLPYGHNYINGSLG-DAVQSGHEMPDPTGVDSAFTIIQMRKEFSGPVMDVENHYEGANESDVRHGFYPALFSGACGITFQQSYENI 339
13 -12.000PF02057.15; F0R8Q2_BACSH/44-344; Glycosyl hydrolase family 59  ali follow..  13  19...........DYPEPQRSQILDMVYKPKFGASISALLVEIPGDGNSTQGSMPSHQHILKEAKRRNPRLTLDGTAWSAPGWIGNGKFWSQDAADYYVSWLKGLRNVYGLELIGCRNEKGAD------YDFVKRLRRTLDANGFTDLRIHAFDNWNAGKLNFVKDMASDKELRDAIDIV--SGHVFYQGIPVSAEEKAMA--EQLGKPIWNTEDHVYKKGFDCLIS-NENYIRYGVTKIVNWY..... 259
14 -11.600PF01301.19; BGAL3_ARATH/39-345; Glycosyl hydrolases family 35  ali follow..  9  4INGQRRILSGSIHYPRSTPDMWEDLIQKAKDGGIDVIETYVFWNLKYDFEGRNDLVRFVKTIHKAGLYAHL--KYVPGISFRTDNEPFKRAMKGFTERIVELMKSENPIILSQIENERQGQLLGAEGHNYMTWAAKMAIATETGVPWVMCKEDFGGPMHHRPVQDLAFGVAR-QKGGSFVNYYMYHGGTNFGRTAGGPFVTTSYDYDAPIDEYGLIRQPKYGHLKELHRAI................ 307
15 -10.400PF16173.5; D3IBS9_9BACT/71-229; Domain of unknown function (DUF4874 topsan)  ali follow..  21  19.....................TLQALKNIRNDGKTLVQLVYYLPEYRTSDFITKVEADLDRVREVGMKAILRFAYTSDQNGSDAPMSSILRHLDQIKPILHHKVGVIACVFIGAWGEWYYSSNHLNNTTAYNQVISKWLEVPEERCVQVRTPKY............................................................................................. 159
16 -9.280PF03662.14; HPSE2_ARATH/26-343; Glycosyl hydrolase family 79, N-terminal domain  ali follow..  8  51.....................SPLLAKAIQAFRTLRIRIG-LFGFSEGCLYMKRWDEVNHFFNATGAIVTFLNALHGRNKLNGTAWGGDWDHTNTQDFMNYTVSKGYAIDSWEFGNELSASVSVELYGKDLIVLKNVIKNVYKN--SRTKPLVVAPGGFFEEQWYSELLRLSGPGVLDVLTHHIYNLGPGNDPKLNQTIQEHGPWAAAWVGEAGGAFNSGGRQV--------SETFINSFW...... 312
17 -9.280PF00331.20; A0A0C4DHX2_FUSO4/85-383; Glycosyl hydrolase family 10  ali follow..  10  56..................................................TFSNADKVVDFATQNGKLI-TLLWHSQL-QNINDRSTLTAVIENHVKTMVTRYKGK--ILQWDVVNEIFAEDGNLR-EDFVGIAFRAARAADPAAKLYINDYNLDKSDYAKLTRGMVAHVNK-PIDGIGSQGHLAAPSPASGVPAALRALAASDAKEIAITELDISGASANDYLTVMNACLAVPKCGITVWGVSDKD 272
18 -9.020PF01791.9; Q8TJ99_METAC/11-248; DeoC/LacD family aldolase  ali follow..  8  93........................EFKENSGLNILGVGYTIYLGSEYEAEMLVQAAQVVYDAHQHGMVSVLWIYPRGAAVKDEKDPHLIAGATGVGACLGT-----------DFVKVNYPKKEGEKSAEIFKEAIKAAGRT----KVVCAGGSSDEAEA--FLKKLHDQIHISRAQGNATGRNIH.............................................................. 236
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;