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Query: PF00303.19; W5XZY7_9CORY/9-269; Thymidylate synthase, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst PYEDLLRKILAEGTHKDDRTGTGTTSLFGAQMRFNLAEYFPLITTKKVHFKSIVGELLWFLRGDSNVAFLHENGVTIWDEWADENGDLGPVYGVQWRSWPTPDGRHIDQIAQAIETLKHNPDSRRNIVSAWNVSEISNMALPPCHLLFQLYVADGKLSCQLYQRSADMFLGVPFNIASYALLTHMLAQQAGLEVGEFIWTGGDCHIYDNHREQVELQLTREPRPYPQLKLAKADSIDAYTFADIEVVSYDPHPLIRGAVAVLast
1 -123.000PF00303.19; W5XZY7_9CORY/9-269; Thymidylate synthase  ali  100  1PYEDLLRKILAEGTHKDDRTGTGTTSLFGAQMRFNLAEYFPLITTKKVHFKSIVGELLWFLRGDSNVAFLHENGVTIWDEWADENGDLGPVYGVQWRSWPTPDGRHIDQIAQAIETLKHNPDSRRNIVSAWNVSEISNMALPPCHLLFQLYVADGKLSCQLYQRSADMFLGVPFNIASYALLTHMLAQQAGLEVGEFIWTGGDCHIYDNHREQVELQLTREPRPYPQLKLAKADSIDAYTFADIEVVSYDPHPLIRGAVAV 261
2 -6.940PF05995.12; Q1DDT5_MYXXD/3-167; Cysteine dioxygenase type I  ali follow..  10  16..............................................................................................LLGWPLPEQTEDIVSMAWLVERLRSSRVD-ELLLVSWLPGQASRVHDHGGSGGA-SWLVRGMLRETRFAWAGDRLVPEVIVGANEGDLLVEFPDTIHRIDNASRHGAVSLHLYAPPMQGMTPY............................................ 162
3 -6.490PF17083.5; SWM2_VANPO/14-144; Nucleolar protein Swm2  ali follow..  14  4.................................................................................................................FRDSPVLLKEYGPYLSYHNDGELSLNAVRICEELFDWQNGDHTIAKEVVQCALDMWFGEEYDLKGFEYIPNLIIQEIDVAKGKNTGEIHRIEFHPSTNEPIDEPLN------------------NLILEEVEVHDF............ 130
4 -6.370PF14496.6; Q886T4_PSESM/1702-1922; C-terminal novel E3 ligase, LRR-interacting  ali follow..  10  52...........................................................................................................ERVWTVLATANQDPQLCMTLNAIAEEPLRLFHDNATCSDGIVLEFNQMEVLIFTRQSLQNVLYQLAVRLYRLSELDAAAREQAG--------DRDEAEVRLAYRVHWASALN--PVPPEHMLFEVHARIRPGELDTARVRTGEQGEPFLSFAA. 205
5 -6.340PF06040.11; Q8UY74_9ADEN/13-145; Adenovirus E3 protein  ali follow..  16  1................................................................................................................IKAETATTPDFRVSKLQLFQPPGTYQCVSGPCHHTFHLI-RRDLSESNTTTHTGGELRGQPTSGIYYGPWEVVGLITLGLVAGGLLVL---CYLY...................................................... 112
6 -5.980PF13743.6; U5L7Y1_9BACI/27-219; Thioredoxin  ali follow..  14  75.....................................................................................................................................ENPVSSPHLASIAIKAAELQGRKAGIRFLRKLQEVLFLEKQNISNFDVLKS-CAQNVGLDVVEFVADIHSDSAAKAFQCDLKITSEMDVQEIPTLVFFNENI----EEEGIKVTGYYPYEVYV..... 192
7 -5.950PF04473.12; Q5JHU4_THEKO/395-551; Transglutaminase-like domain  ali follow..  15  1........................................................................................................EKLRTVTKDFTKYSTTLDKAWAILE-WIDENIEYEYTKADYVDALVYNWSKLTSEQKELYDNLTRLYAPNDIIDYAILTAAMLLDSGVSLDISFENSKVGHAAV..................................................... 115
8 -5.870PF08030.12; RBOHF_ARATH/746-927; Ferric reductase NAD binding domain  ali follow..  10  15PFISILKDLLNN---IVKMEEHADSISDFSRSSEYSTGSNGDTPRRKRILKTTNAYFYWVTREQGSFDWFKGVMNEVAELDQRAKNGVDIVSGTRVRTHFAR-----PNWKKVLTKLSSKHCNARIGVFYCGVPVLGKELSKLCN.................................................................................................................... 182
9 -5.840PF01085.18; W5MLT6_LEPOC/24-184; Hedgehog amino-terminal signalling domain  ali follow..  17  81...........................................................................................................DCVNALAIAVMNQPGVRLRVTEGWDEDGHHPPN-----------------SLHYEGRAVDITTS-DRDPRKYGTLAQ-LAVEAGFD---WVYYESKSHVH...................................................... 159
10 -5.750PF10481.9; G7NUK3_MACFA/1-307; Cenp-F N-terminal domain  ali follow..  11  18........................................................................................................QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQ----------KVENEKTEGTNLKRENQ---RLMEICESLEKTKQKISHELQVKESQ-------VNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCS........... 143
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 1 0 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;