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Query: PF00493.23; MCM2_YEAST/480-703; MCM P-loop domain, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst EEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHLast
1 -118.000PF00493.23; MCM2_YEAST/480-703; MCM P-loop domain  ali  100  1EEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSH 224
2 -38.700PF13337.6; R6V945_9CLOT/51-507; Putative ATP-dependent Lon protease  ali follow..  13  161ELKQGRKAFTKEEWMDVMLRSIGMEPDTLSYREKWLLLARMLPL---------VENNFNLCELGPRSTGKSHIFK---EISPNSILVSGGQTTVANLFYNMGRKTVG----------LVGLWDCVAFDEVAGINFKDKDGMKDYMASGSFARGKE----EKSASASMVFVGNINQSVDVLLKTFPPEMGTDTAFLDRMHCYIPGWEISKFRPHHFTNDYGFITD 367
3 -24.200PF09739.9; W4XGD3_STRPU/34-609; Mini-chromosome maintenance replisome factor  ali follow..  11  284.......LKEAGVIRDQLRWLLSQVLLCDALTADYLILHLLSSVYARREVCALGKLSLNLTGIPQDPEFVATLYALIEQLVSKSHLLPLTLSNMNKLKLTPKKDYTANR--LKSGLLQLTDRTHLVLDELDANGVMNLAALGNIISWQKVDYDFNYHKTEFHTNVGVLVLSD.................................................... 453
4 -23.500PF01078.21; Q8EJV7_SHEON/193-396; Magnesium chelatase, subunit ChlI  ali follow..  22  4........................EVIGQYQAKQALEIAAAGN---------------NLLMLGPPGTGKTMLASRMMALLPALNYEEALEVAAIHSVAGINIKPVGGGSIPKPGEISLAHRGVLFLDEVAEFPRKVLDCLREPMETGEVVISRAAAKLTFLSRFQLIAAMNPSPSGDTPDQIQRYLARLSGPFIDRFDLTIEV.................... 196
5 -17.300PF07726.11; Q87G66_VIBPA/36-166; ATPase family associated with various cellular activities (AAA)  ali follow..  24  1..........................................................HILVEGPPGLAKTRAVKSLSDCVHRIQFTPDLLPA--DLTGTDIFRPETGEFTFQSGPIF---NSLILADEINRAPAKVQAAMLEAMAEKQVTAG--RHTYALPELFLVMATQNPI--------EQEGTYPLPEAQLDRF.......................... 129
6 -13.200PF00158.26; Q8E8E7_SHEON/154-320; Sigma-54 interaction domain  ali follow..  19  22........................................................NAVVLIQGESGTGKELVARQLHLLSGRQFVPVNCGSIAPELLES-TAGAFTGAKGNREGLFSFASGGTIFLDEIGEMPLKMQTALLRVLEQKAIR--PVGSEKEVNIDVRVIAATN------RTLVDEVEAGNFRRDLYYRLNVLDIL.................... 167
7 -11.700PF05496.12; RUVB_BACAN/21-179; Holliday junction DNA helicase RuvB P-loop domain  ali follow..  19  8........................QYIGQDKAKHNLEVFIEAAKMREET---------HVLLYGPPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLAAV-------------LTSLQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIPSARSVRLDLPPFTLVGATT-------------RAGALSAPLRDRFGVL....................... 156
8 -11.500PF08298.11; YEAG_ECOLI/19-380; PrkA AAA domain  ali follow..  16  58.......................EEFYGMEDAIEQIVSYLKHAAQGLEEKKQ-------LYLLGPVGGGKSSLAERLKSLMPFCLFNPQSILQQIAIAKTEPGDENNQDISGYSGALCRANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGT--EGISALPFNGIILAHSNE------SEWVTFRNNKNNEAFLDRVYIVKV---CLRISEEIKIYEKLLN.. 329
9 -9.750PF14532.6; C6X8G9_METGS/136-273; Sigma-54 interaction domain  ali follow..  12  21........................................................KSPLLLIGEQGSGAELCAKFLHNPDTPWLSLTDYEQLAT----------------APLDILEQVQEGMLFIPEVADLSKNQQKGLQLLLARAD-LVVAGRFDNLLLQSISATSLRIP................................................... 136
10 -9.710PF00004.29; LON_BRECH/351-493; ATPase family associated with various cellular activities (AAA)  ali follow..  19  1...........................................................LCLVGPPGVGKTSLARSVARALGREFVRISLGGVRDEAEIRGHRRTYVGALIIQGMKQAGTINPVFLLDEIDKLASDFRSALLEVLDNQNDKFSDHYIEETYDTNVMFITTANSLD-------------TIPRPLLDRMEVISI..................... 140
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;