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Query: PF00557.24; YOD1_SCHPO/228-435; Metallopeptidase family M24, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst DIMSRVNIATVAAIRSVQPCIKPGITEKELAEVINMLFVYGGLPVQESPIVLFGERAAMPHGGPSNRRLKKSEFVLMDVGTTLFGYHSDCTRTVLPHGQKMTERMEKLWNLVYDAQTAGIQMLSHLSNTSCAEVDLAARKVIKDAGYGEYFIHRLGHGLGLEEHEQTYLNPANKGTPVQKGNVFTVEPGIYIPDEIGIRIEDAVLASDLast
1 -111.000PF00557.24; YOD1_SCHPO/228-435; Metallopeptidase family M24  ali  100  1DIMSRVNIATVAAIRSVQPCIKPGITEKELAEVINMLFVYGGLPVQESPIVLFGERAAMPHGGPSNRRLKKSEFVLMDVGTTLFGYHSDCTRTVLPHGQKMTERMEKLWNLVYDAQTAGIQMLSHLSNTSCAEVDLAARKVIKDAGYGEYFIHRLGHGLGLEEHEQTYLNPANKGTPVQKGNVFTVEPGIYIPDEIGIRIEDAVLASD 208
2 -8.020PF15952.5; B4GEG8_DROPE/1-237; Enhancer of split M4 family  ali follow..  11  25....HTSASMTATAATPLGVPKTVRRMRKVWQPLRRLLTVGGKGRPAPL------TLAHPNNVDLNNTQQQQQQQQQQIELILEDESKSTPEESIYKYGAELRQLPVEDEVSLTQPPNTPTLISS------VYVEKASAQSCGACPHGRNCQHTHHNSNSNRNTTTTTATSSATAAQLPSNLWDLQLPLQYISTDNGTRVDDDLL... 221
3 -7.370PF12388.8; H8MF84_CORCM/49-254; Dual-action HEIGH metallo-peptidase  ali follow..  10  2.YVGRDAHVTLEASRELLPLEEGSAEQYRTTNQVGTSVTKICVNPTAAFNSYSNLSQGLDLAIANYNEQGLR----LTFRGPTTGCTANIS--------------------AETTTGTGGQAGFPSNGMPYGVFYITGLDSYSADVNEHVITHELGHAIGFR-HS........................................... 140
4 -7.170PF00278.22; Q088K9_SHEFN/29-368; Pyridoxal-dependent decarboxylase, C-terminal sheet domain  ali follow..  9  43.LARLGSGFDIVSGGELSRVLQAGGDPKKVVAEMEQALNIGIYCFNVESSAELEQLNEVASRLGKVAPV----SLRINPDVDAGTHPYISTGLKENKFGIAMEEAEVVFARAAELAHLHVKGVDCHIGSQLTEIKPFLDAMLGEQGIQIEHFD-VGGGLGVTYNSETPPHPDAYAAALLEKLKLIFEPGRAIAANAGIFVTQVLYLKE 266
5 -6.960PF01624.20; MUTS_AGRFC/20-137; MutS domain I  ali follow..  10  11..................................................................KANNPGSLLFYRMGDFYELFFDDAVEA------------SRALGITLTKRGQHMGHDIPMCGVPVHAADDYLQKLILR-----------GYRVAVQIEDPAEAKKRGSKSVVKRDVVRLVTPGTLTEE.............. 117
6 -6.920PF13583.6; Q3BQ26_XANC5/186-409; Metallo-peptidase family M12B Reprolysin-like  ali follow..  12  3............................................AVVDVLVGYTPGLVRELGSVDAYLVAVTNRAYSDSQVNGRLRLIGTQQVNYTDSTTDDAALNDLTEASGTSSLAALHSTRDTQGADLVALLRPYRANQGACGVAITFAHEIGHNLGLA-HDK---DSGPGAFTYAYGWRQTLDEGSF................. 188
7 -6.900PF02031.16; SNPA_STRCO/80-212; Streptomyces extracellular neutral proteinase (M7) family  ali follow..  12  1..........................................................................................AVTVYYSATNAPSFRSQISRSA-QIWNSSVSNVRLAESSSGADFAFLDYRQNQQYDSTRVTAHETGHVLGLP-DHYS......................................... 97
8 -6.810PF01791.9; Q8TJ99_METAC/11-248; DeoC/LacD family aldolase  ali follow..  14  89DQVAEFKENSGLNILGVGYTIYLGSEYEAEMLVQAAQVVYDAHQHGMVSVLWIYPRGAAVKDEKDPHLIAGATGVGACLGT-------DFVKVNY--PKKEGEKSAEIFKEAIKAAGRTKVVCAGGSSDEAEAFLKKLHDQIHISR-------AQGNATGRNIHQ........................................... 237
9 -6.290PF10462.9; Q6LPV2_PHOPR/268-569; Peptidase M66  ali follow..  45  189...............................................................................................................................................DASLGNEFSHEVGHNFGMG-H............................................ 208
10 -6.200PF00359.22; Q9KMS5_VIBCH/6-152; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2  ali follow..  17  9QLQAKANNWREAIKIGTDMLIASGAITPAYHEAIIASVEQLG------PYICIAPNLALPHARPENGVLRTAALVTLQEPIYFEGEDEPVDVLITLAGSSSDEHMEGLMEVTQVLDDENSATGVDLDKLRRCRDKQQVYAVIDQ................................................................ 147
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Schwarzenbacher R, Godzik A, Jaroszewski L. The JCSG MR pipeline: optimized alignments, multiple models and parallel searches. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):133-40. Epub 2007 Dec 5.