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Query: PF01266.24; Q89E97_BRADU/6-350; FAD dependent oxidoreductase, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst DAIVIGGGIHGCSTTLHLCLAGLKPVLIEKDYAGRHASGVNAGGVRQLARHVPEIPLSIRSMGIWERITDLLDDDCSFESHGQVLVAENEDELAVCRARVAELNALGFTHEELIDATELRRLVPAVAETCPGGVVSRRDGAANPAQTTTAFRRKAEQLGATVREGVAASNIRYSDGLWYVDVGSDTYAAPVLVNAAGAWAGKIAAALGEPVPVETVAPMLMITSRVPHFIDPVVILRGRKLSFKQFSNGTVLIGGGHLATPYQDRNETVLDWKSLAISARTVFELFPVMRSATIVRAWAGIEAKMKDDIPVFGPSSRHKGLYHQFGFSLHGFQLGPGAGAVMAELLast
1 -103.000PF01266.24; Q89E97_BRADU/6-350; FAD dependent oxidoreductase  ali  100  1DAIVIGGGIHGCSTTLHLCLAGLKPVLIEKDYAGRHASGVNAGGVRQLARHVPEIPLSIRSMGIWERITDLLDDDCSFESHGQVLVAENEDELAVCRARVAELNALGFTHEELIDATELRRLVPAVAETCPGGVVSRRDGAANPAQTTTAFRRKAEQLGATVREGVAASNIRYSDGLWYVDVGSDTYAAPVLVNAAGAWAGKIAAALGEPVPVETVAPMLMITSRVPHFIDPVVILRGRKLSFKQFSNGTVLIGGGHLATPYQDRNETVLDWKSLAISARTVFELFPVMRSATIVRAWAGIEAKMKDDIPVFGPSSRHKGLYHQFGFSLHGFQLGPGAGAVMAEL 345
2 -40.700PF06039.15; C1DJ81_AZOVD/24-513; Malate:quinone oxidoreductase (Mqo)  ali follow..  14  4DVLLIGGGIMSASLGTYLKELDWTIDIYERDQVAEESSNPNAGTGHSYTSEKPDGHVDISKALAVTESFEISNPKSFINDVPHISFVWGDENVAFLKKRHEAMQHSSLYREYTEDHATINEWAPLVAGQKVAATRMPIGTDVNFGEITRQLMGALTRHGVTLNLKHEVRDFVRNDDGTWNVTEEKTVKAKFVFIGAGGGALPLLQKTGIGYAGFPVGGQFLYTTNGKASVGAPPMSVPHLDTRVIDGKRAILFGPFATFSTKFLKKGSLLDMLSQEERIEELREYFPQAKAEDWKLLTAGQRVQVIKKDPGTEVVAAADGSIAALLGASPGASTAAPIMLTVLEK 444
3 -19.800PF05834.12; LCYB_ARATH/84-479; Lycopene cyclase protein  ali follow..  14  1DLAIVGGGPAGLAVAQQVSEAGLSVCSIDPSPKLIWPNNYGV----------------------------------------------------------------------WVDEFEAMDLLDCLDTTWSGAVVYVDEGVVNRKQLKSKMLQKCITNGVKFHQSKVTNVVHEEANSTVVCSDGVKIQASVVLDATGF-SRCLVQYDKPYNPGYQVAYGIVAEVDGHPFDVDKMVFMDWRLYAMPFSSNRIFLEETS-------VARPGLRMEDIQERMAARLKHL-GINVKRIEEDERCV-------IPMGGPLPVLPQRVVGIGSTGYMVARTLAAAPIVANA 298
4 -15.500PF01494.19; TCMG_STRGA/16-391; FAD binding domain  ali follow..  15  3PVLIVGGGLTGLSAALFLSQHGVSCRLVEKHRGTTVLTRASG--------------ISSRTMELLRGV----GLERTVIERG--------PKLVEGARWRELGQPADQIPWVVIRANGLHDLENAVTVEEPSLDVGHLS-WCGQDRLEPILRDEAVRRGARIDFNTRMEAFTADESGVTATIVDQTVRARYLIAADGVRSP-VRETLGITRTGHGTIGNAMSVLFKADLRDTVKGRRFVICYLPNPDEPGVLQLPEGFFFDPRETSPEQFTDERCAQIIRTATGLPGLPVEVQMARPWE-ARSYRSGRVFLAGDAAHVHPPAGAFGAN-GGIQDAHNLAWKLAAV 348
5 -14.900PF01946.17; THI4_SCHPO/60-299; Thi4 family  ali follow..  12  19DIVIVGAGSAGLTAAYYIGTRDLKIAIIEASVAPGGGAWLGGQLFSAMVVRKPADLFLNEVVKHAALFTSTVMARTLALPNVKLFNATAVEDLIVKEGKDGKQRIAGVVTNWTLVSLNHGLQSCMDPNTINAHLVVSATGHDGPFGAFCVKRLASAQLVSNLH---DMRPLDMNRAEDLIVKGTREVFPGMIVGGMELSEFDGANRMG---PT.................................................................................................................................... 239
6 -14.700PF13738.6; E4RQY1_LEAB4/3-286; Pyridine nucleotide-disulphide oxidoreductase  ali follow..  18  1..VIIGGGPIGMACGIECKKAGLDYVILEKGCLVNSLYHY---------------------------------------------------------------------------PTTMTFFSTSERLELDNIPFVSNSAKPTRAEALEYYRRVAQNQQLNIHLFEEVSDVYKVEKGFEVKTSKRTYSAEKVILATGFYDIP------LGIPGEDLKVKHYYKDPHFYAFQKI-----------------VVIGANNSA...................................................................................... 161
7 -13.200PF00890.24; Q8EJR4_SHEON/7-411; FAD binding domain  ali follow..  15  1DSLVVGAGLAGLRVAIASKERGLDTLVLSLIPAKRSHSAAAQGGMQASLGNAVKGMGDDEDVHFQDTVKG--SDWGCDQEVARMFAHCAPKAVRELANRVSAGPREVIVNAQKVTLQEAEEAHGLINARDFGGTKKWR-ADGTGHSLLYAMDNKAISMDIPVHERVEALALIHDGGVVARCLISGEYVAKSTTIATGALETGVATLGNMEAPTAIVPVGILTTEGCRGDGGLLRDKDGYRFMPDYEPESRRMTEHMRKGKGVDSPYGPHLWLDITLLGRKHIETNLREV--QEICENFLGI-DPAKDWIPVRGESPQLKGLFSVGEAACWDMHGFNRLG...... 401
8 -13.000PF13450.6; B4RE46_PHEZH/425-493; NAD(P)-binding Rossmann-like domain  ali follow..  17  1...IVGAGFAGSVLAERLTQLGKRVLLVDRRPHVGGNA................................................................................................................................................................................................................................................................................................................... 36
9 -12.900PF12831.7; D3E9Q8_GEOS4/21-437; FAD dependent oxidoreductase  ali follow..  16  1DVVVVGGGPTGIAAAIAAANNGANTLLIEQRGFLGGMGTTALVPAFCPFTDHEKPVIRGIGLELMERMKANCKPSYITEYKEQLDWVP-----------------------------------------------------IDVEVLKRVYDEALLESGAKVLFHTFVGQLVMNPGGHGVKSGRSIVEAKYVIDATG--DADIAALAGAPFQK.................................................................................................................................... 165
10 -12.900PF03486.14; Q8EKN8_SHEON/4-393; HI0933-like protein  ali follow..  13  2DVIIIGAGAAGLMCAATAGYRGRDVLVLDNA--------------------------------------KQAGRKILISGGGRCNFTNLKVEPANFICGNPHFVKSALARYPSQQFIELVERHGIEYHERDHGQLFCND---SAKEIVTMLLTECEWAGVSIKLRTDILSVGKEAGRFELNTSNGELSCDSLVIATGGLS-QLAEQFGLKV...................................................................................................................................... 182
11 -12.400PF06100.11; G8PAJ4_PEDCP/22-520; MCRA family  ali follow..  12  3SAYLVGSGLASLAAATFLVRAGDRIHVLEELGLPGGDGIWNEQKGYIIRGGREMEPHFETLWDLFRSIPSLENEDVSVLDE-TLSRKAINEIIKVALTPEDQLQDKQIDEEPWASALEMRRYLLRFVHHIATLSDLSSLRFTK-ESLIIPMVKFLESKGVHFQYNTTVDNILVNRVGTGKVATKLEMTVD........................................................................................................................................................... 251
12 -12.400PF13454.6; A1R325_PAEAT/10-186; FAD-NAD(P)-binding  ali follow..  12  1..ALIGAGPRGTSVLERLLANTLHIDVVDPYPAGSGHVW------QPEQSRLFLMNTQSFYPTLIPEDPQLAPPLAG----------------GSFDQWREARRRDGMGLNDAEKAELSTLESHNFPSRAIYGRYLRQ--------TLDGLLERLPDGVKVTFHETLAVAARPVADGFDVELASGALTVGSVVLALG.................................................................................................................................................... 175
13 -12.300PF00996.18; I1K489_SOYBN/1-433; GDP dissociation inhibitor  ali follow..  12  6DVIVLGTGLKECILSGLLSVDGLKVLHMDRNDYGGESTSLNLIQLWKRFRGDDKPPPHLGASRDYN-IHTDVTKYLYFKAVDGSYVFNKGKKVPANDMEALKSPLMGLFEKRRARKIAKYGLDDNTIDFIGHALFQGGSPYIYPLELPQAFARLSAVYGGTYMLNKPECKVEFDEEVVGVTSEGETAKCKKVVCDPSYLPGKVRKVGRVARAIAIMSHPIPSTDDSHSVQKSDMYLFCCSYTHNVAPKGKFIAFVSTEAETDQPAIELKPGIDLLGPVDEIFFDIYDRYEPVNEPTLDNCFISTSYDATTHFESVDDVLNMY....................... 422
14 -12.100PF04820.14; Q9A4M5_CAUVC/6-464; Tryptophan halogenase  ali follow..  13  1KIVIVGGGTAGWISASGLAAVPITIELIESAEIG--TVGVGEATVPHIRYFNARLGLDEADFMRKTQATIKLGIQFPFGAYGHAIDGLPFHQHWLAARARGEAGPIETYSLPIMAGLAGKFAPPSSDPRSLGSTFNYA--QFDASLYAQYLRAYSEARGVTRTEGKITSVQQRPNDVTGVTLEDGVVEGDLFIDCSGFRGLLIEGALQAGY------TQWLPCDRAVAAPCASVEAPTPYTRATADRFGRVGNGHVYCSSYVSDDEAARALVENLDGELQQDPRFLR-FVTGRRKKQWFKNVVAVGLSSGFLEPL------------ESTSIHLIQVAVTTLLEL 354
15 -11.800PF13434.6; Q4K9A7_PSEF5/9-357; L-lysine 6-monooxygenase (NADPH-requiring)  ali follow..  9  4DLIGIGFGPSNLALAIALEERGQDALFLDKQADYRWHGNTLVTQSELQISFLKDLVTLRNPTS-FVNYLKHHGRLVDFINLGTFYPCRMEDYLRWVAGHFQEHSRYG-EEVLAIEPVLHNQQVEALRVISRDAQGSELVRTTRSVVVSAGGTARVPETFKGLKGDARVFHHSQYLERMASQPCVSGKPMNIAIIGGGQSAAEAFIDLSVQADIIMRGSALKPADDSPFVNEVFSPAFTDLVFQTGSERERLVSEYQNTNYSVVDIDLIERIYGIFYRQKVSGIARHTFRTMTTVEKA-LGIELILRNSASGEREVRHYDAVVLATGYER................ 349
16 -10.100PF00732.19; G3XSF9_ASPNA/42-353; GMC oxidoreductase  ali follow..  14  2DYIIAGGGLTGLTTAARLTEPNISVLVIESGATNNQTALIRSGNGLGGSTLVNGGTWTRPHKAQVDSWETVFGNE--HGVNGTVHAGTGDDYSPIVKALMSAVEDRGVPTKKDFGCGDPHGVEDQVRSDAAREWLLPNYQRPNLQVLTGQYVGKVRAVGVEFGTHKGNTHNVYAKH--EVLLAAGSAVSPTILEYSGIGMKSILEPLGIDLPV.................................................................................................................................... 303
17 -9.990PF02558.16; Q9K9R6_BACHD/6-154; Ketopantoate reductase PanE/ApbA  ali follow..  16  1.VAVIGSGSIGLLLYAYLKLANWPALLVTNRPEQADH----------------------------------------LNKEG-LTFVAKSGEHQPISVTATPLSSFSAEEAEVGKSFAVKALLPQLQRKKWDGLVFFQNG---------------------MTHLEILRQIPARAICCGIVEIGAKRESDVRVQHTGDGAIWIGDMVG......................................................................................................................................... 149
18 -9.950PF00070.27; AHPF_ECOLI/357-437; Pyridine nucleotide-disulphide oxidoreductase  ali follow..  28  1RVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAP......................................................................................................................................................................................................................................................................................................................... 32
19 -9.820PF01134.22; MNMG_DESPS/17-409; Glucose inhibited division protein A  ali follow..  11  1DIVVIGAGHAGCEAALAAARLGHKTLLAVMNVDTIGAMSCNPAI-------------------------------------GGLAKGHLVREIDALGGEMARVIDATSIQFRRLNTSK-------------GPAVQSSRAQADRLLYRLQMKSVIEHQENLTVSQTEVNGFIVEDGITGVTTTIDKISVKAAIVATGTFLNGLVHIGLKNFPAGRLGDGPSTGTGTVPRIDSLTIDYSELEAQESDMPPAHFSFDSQGKGYTLPQLPCYITYTNEKEVQIEMLQSIKGLENARIIRPGYAIEYDYIDPLGL--ATKKIENLYLAGQINGSGYEEAAAQGLMAG.. 382
20 -9.260PF07992.14; I6L922_STRMU/209-496; Pyridine nucleotide-disulphide oxidoreductase  ali follow..  12  2DVLVIGGGPAGNSAAIYAARKGVKTGLLAETMGGQVME--------------------TVGIENMIGTPYVEGPQ-----------------------------------------------------------------------LMAQVEEHTKSYSVDIMKA-PRAKSIQKTDLVEVELDNGHLKAKTAVLALGAKWRKINEFFNKGVTYCPHCDGPLFTDKKVAVIGGGNSGLEAAIDLAGLASHVYILEFLPELKADKILQDRAEALDNITILTNVATKEIDHVEGLRYSDRTTNEEYLLD-----------LEGVFVQIGL.................. 234
21 -9.030PF06690.11; D7DUD4_METV3/2-259; Protein of unknown function (DUF1188 topsan)  ali follow..  22  43QAIIFGAYLSGNYIANTLKADCGEVILIDSQ.......................................................................................................................................................................................................................................................................................................................... 73
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 2 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.