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Query: PF01351.18; RNH2A_SCHPO/66-277; Ribonuclease HII, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst LGVDEAGRGPVLGPMVYAVAYCPVDFDLTNYGFADSKTLASLKREELLKLICNKSNELGKNVGWSTMSISARELAAGMLRYRNKYNLNLQAHDTTIDLIKKVYESGINVTEIYVDTVGPPISYQEKLQAHFPQAKVTVTKKADSLFPIVSLASICAKVTRDIQLECARESIRTENWGSGYSSDARTTEWLKVNVDKIFGWKGDIVRYSWKTALast
1 -109.000PF01351.18; RNH2A_SCHPO/66-277; Ribonuclease HII  ali  100  1LGVDEAGRGPVLGPMVYAVAYCPVDFDLTNYGFADSKTLASLKREELLKLICNKSNELGKNVGWSTMSISARELAAGMLRYRNKYNLNLQAHDTTIDLIKKVYESGINVTEIYVDTVGPPISYQEKLQAHFPQAKVTVTKKADSLFPIVSLASICAKVTRDIQLECARESIRTENWGSGYSSDARTTEWLKVNVDKIFGWKGDIVRYSWKTA 212
2 -7.960PF16784.5; Q2FUP5_STAA8/21-220; Putative HNHc nuclease  ali follow..  11  1.GVE---------EQSHIDLLENGYPLKAEVEVPDNKKLSIEQRKKIFAMCRDIELHWGEPVESTRKLLQTELEIMKGY---EEISLRDCSMKVARELIELIIAFMFHHQ...................................................................................................... 98
3 -7.820PF12686.7; K9XG69_9CHRO/9-227; Protein of unknown function (DUF3800 topsan)  ali follow..  10  4..LDDSGSPKPNPKFGMGGVLINRGHPLHGSEIRSKKNLSEVEYQQFMEDLTNTIVRCPIIVHACVISRHGYLKRYLEKYGEDTWEMMKSAFTILVERAAKYVAAKNGTLMVYFEAAGKRENKYFPLSANDFSSLLRGIDSKKKSNAVMQIADLCLYPVV.................................................... 217
4 -7.720PF07395.11; Q88D85_PSEPK/35-298; Mig-14  ali follow..  10  105....................................EDLSKKFRYNQRRELRL-LEEAGGVVRPISDFSAQEIASMYCDLFLRRWGFPATGAERMADVLERLREL-LIGSVLLLDGKPIAIQLVYRVEAPEWISVEYINGGVDPETKAFSPGSVLSFLNTQAAWED-RNKPLRFSFGRA-----------DREYKDRWCNPVPVYQ...... 263
5 -7.030PF03266.15; NTPTH_METAC/3-167; NTPase  ali follow..  12  5TGSPGVGKSTVVAKTA--------------------EKLAEKPGFKIGGIRTAEIRKEGHREGFSIRDLATGKTGILSHVKGSGPRLGKVNLDDLERIGANAVRNALACDLVVIDEIGPMELISQSFVSAVEEVPVLAVLHHSSRHPLAQRFR-VDKGNRDELPEKI............................................. 164
6 -6.760PF00817.20; Q74KV6_LACJO/16-168; impB/mucB/samB family  ali follow..  10  8ASVEMRDNPSIRNAVLIGGVVATANYIARSYGAHSAMPTAKAVR---FEKYRAVSAEIHQLMHKITDRVESVALDEAYLDVTENKLNLTDPVRIAALLQERIYQRIGLTSSF------------------------------------VSYNKFLAKMGSE................................................... 153
7 -6.370PF12967.7; Q9WZX8_THEMA/1-158; Domain of Unknown Function with PDB structure (DUF3855 topsan)  ali follow..  13  1..............................MRLMDILEILYYKKGKEFGILEKKMKEIFNETGVSLEPVNSELIGRIFL----KISVLEEGEEVPSFAIKALTPKENAVDLPLGDWTDLKNVFVEEIDYLDSYGDMKILSEKNWYKIYVPYSSVKKK-NRNELVEEFMKYF......................................... 136
8 -6.180PF03708.14; ENV_RSVSA/157-402; Avian retrovirus envelope protein, gp85  ali follow..  29  192.AIDRAWQGPVGGPCYLGTMLAPKHTDILKVLVNSSRTGIRRKRS....................................................................................................................................................................... 246
9 -6.060PF10491.9; G1MUP9_MELGA/31-239; NLS-binding and DNA-binding and dimerisation domains of Nrf1  ali follow..  13  1........GPV-G-MAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNP-------VFKVFGAAPLENVVRKYKSM------ILEDLESALAEHAPAPQEVNSELPPLTIDGIPVSVDKMTQAQLRAFIP..................................................... 136
10 -5.790PF07302.11; Q89Q90_BRADU/10-227; AroM protein  ali follow..  10  1IGVVVIGQSPRPTVASEIAAVLSPGIEIELRGALDG--MSRAEIDAIPDGVTISKKEVERRASQQITRFKHEGVGVTLMACTGKFPNLAADGAILHNLVEAVLPKG-----VFSPLPEQTVLIDKKWQRDGVEVVGITLRPGSSDAVVDEAARTMADLEPDLVV................................................ 181
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.