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Query: PF01494.19; TCMG_STRGA/16-391; FAD binding domain, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst EVPVLIVGGGLTGLSAALFLSQHGVSCRLVEKHRGTTVLTRASGISSRTMELLRGVGLERTVIERGPKLVEGARWRELGQPADQIPWVVIRANGLHDLENAVTVEEPSLDVGHLSPTRPYWCGQDRLEPILRDEAVRRGARIDFNTRMEAFTADESGVTATIVDQATGEQSTVRARYLIAADGVRSPVRETLGITRTGHGTIGNAMSVLFKADLRDTVKGRRFVICYLPNPDEPGVLQLPEVPAVLQLFDEDRWIFGFFFDPRETSPEQFTDERCAQIIRTATGLPGLPVEVQMARPWEMSHNSARSYRSGRVFLAGDAAHVHPPAGAFGANGGIQDAHNLAWKLAAVLKGTAGDALLDTYEQERLPIGAAVADQALast
1 -133.000PF01494.19; TCMG_STRGA/16-391; FAD binding domain  ali  100  1EVPVLIVGGGLTGLSAALFLSQHGVSCRLVEKHRGTTVLTRASGISSRTMELLRGVGLERTVIERGPKLVEGARWRELGQPADQIPWVVIRANGLHDLENAVTVEEPSLDVGHLSPTRPYWCGQDRLEPILRDEAVRRGARIDFNTRMEAFTADESGVTATIVDQATGEQSTVRARYLIAADGVRSPVRETLGITRTGHGTIGNAMSVLFKADLRDTVKGRRFVICYLPNPDEPGVLQLPEVPAVLQLFDEDRWIFGFFFDPRETSPEQFTDERCAQIIRTATGLPGLPVEVQMARPWEMSHNSARSYRSGRVFLAGDAAHVHPPAGAFGANGGIQDAHNLAWKLAAVLKGTAGDALLDTYEQERLPIGAAVADQA 376
2 -27.700PF08491.10; Q6CJX6_KLULA/205-477; Squalene epoxidase  ali follow..  15  1.............................................................................................................................................................................KAHLTFVCDGIFSRFRKELSPDHIPSVGSSFVGMSLFHANIPS------------KNHGHVILGTSHMPVLVYQISSEERILCAYNSARLPKDIKSWLTTDVKPYLPKSLLPSDKAVEDGKFRSMPNSYLPAKQNTVTGLCVIGDALNMRHPLTGGGMAVGLNDVALLIKTVLDFSDRETVLDELLEYHFERKQYDSVINVLS 195
3 -25.400PF05834.12; LCYB_ARATH/84-479; Lycopene cyclase protein  ali follow..  11  1..DLAIVGGGPAGLAVAQQVSEAGLSVCSIDPSPKLIWPNNGVWVDEFEAMDLLDC-LDTTWSGAVVYVDE--------------------------------------GVKKDLSRPYGRVNRKQLKSKMLQKCITNGVKFHQSKVTNVVHEEANSTVVC------SDGVKIQASVVLDATGFSRCLVQYDKPY---NPGYQVAYGIVAEVDGHPFDVDKMVFMDWRDKHLDSYPEKIPTFLYAMPFSSNRIFLEETSLVARPGLRMEDIQERMAARLKHL---GINVKRIEEDERCVIPMGGPLPVLPQRVVGIGGTAGMVHPSTGYMVARTLAAAPIVANAIVRYLGPSSNSLRGDQLSAE............ 319
4 -22.600PF04820.14; Q9A4M5_CAUVC/6-464; Tryptophan halogenase  ali follow..  12  1..KIVIVGGGTAGWISASGLAAVPITIELIESAEIGTVG--GEATVPHIRYFNARLGLDEAMRKTQATIKLGIQFCDARARGEAGPIETYSLPIMAGLAGKFAPPSSDPRSLGSTFNYAYQFDASLYAQYLRAYSEARGVTRTEGKITSVQQRPNDGFVTGVT---LEDGRVVEGDLFIDCSGFRGLL-------------IEGALQAGYEDWTQWLPCDRAVAAPCASVEAPTPYTRATAD--------RFGWRWRIPLQHRVGCSSYVSDDEAARALVENLDGE----LQQDPRFLRFVTGRRKKQWFKNVVAVGLSSGFLEPLESTSIHLIQVAVTTL---LELFPHRGFDPADEDEYNRVMDLEFERIRD.. 381
5 -15.700PF06039.15; C1DJ81_AZOVD/24-513; Malate:quinone oxidoreductase (Mqo)  ali follow..  2TVDVLLIGGGIMSASLGTYLKELDWTIDIYERLDQVAEESSNPWNNAGTGQFWAHQIDKGVLSNPKSFINDVPHISFVWGDENVAFLKKRHHATINEWAPLVMEGRTAGQKVAAMPIGTDVNFGEITRQLMGALTRHGNVTLNLKHEVRDFVRNDDGNVTVADLAKGGEEKTVKAKFVFIGAGGGAPLLQKTGIPEADGYAGFPVGGQFLYTTNPEVVERHLAKVYGKASVGAPPMSVPHLDTRVIDGKRAILFATFSTKFLKKGSLLDMPRSLSTDNFMPIMHAGLDNLPLSTYLIGQLMLSQEERIEELREYFAGQRVQVIKKDPEKGGVLQFGTEVVAAADGSIAALLGASPGASTAA-----PIMLTVLEK. 444
6 -15.500PF01266.24; Q89E97_BRADU/6-350; FAD dependent oxidoreductase  ali follow..  15  1..DAIVIGGGIHGCSTTLHLCLAGLKPVLIEKDYAGRHASGVNALSIRSMGIWERIDDDCSFESHGDELAVCRARVAELNALGFTHEELIDATELRRLVPAVAETCPGGVVSRRD-----AANPAQTTTAFRRKAEQLGATVREGVAASNIRYSDGLWYVDVGSD------TYAAPVLVNAAGAWAGIAAALGEPVPVETVAPMLMITSRVPHFIDPVVILRGRKLSFKQFSNGTVLIGGG---------------HLATPYQDRNETVLDWKSLAISARTVFELFPVMRSATIVRAWA-----IEAKMKDDIPVFGPSSRHKGLYHQFGFSHGFQLGPGAGAVMAEL............................ 345
7 -14.900PF12831.7; D3E9Q8_GEOS4/21-437; FAD dependent oxidoreductase  ali follow..  19  1..DVVVVGGGPTGIAAAIAAANNGANTLLIEQRGFLGGMGTTALVPA---------GIGLELMERMKANCKPSYITEYKEQLD-----------------------------------WVPIDVEVLKRVYDEALLESGAKVLFHTFVGQLVMNPGGHGVNLVLLNKSGRSIVEAKYVIDATG-DADIAALAGAPFQ................................................................................................................................................................................... 164
8 -14.600PF03486.14; Q8EKN8_SHEON/4-393; HI0933-like protein  ali follow..  13  2..DVIIIGAGAAGLMCAATAGYRGRDVLVLDNAKQAGRKILISG-SQQFIELVERHGIEYHERDHGQLFCNDS--------------------------------------------------AKEIVTMLLTECEWAGVSIKLRTDILSVGKNEAGRFELNTSNG-----ELSCDSLVIATGGLSQLAEQFG-GLSGPAQISNYWKAGETIKINLLPNMDAAQAIEQQLAAHPKQSLRNTLSLWLPKRLVEVLFDEVLLNKALNQLVHAERAKLVDDLHRTEGYRTAEVTLGGVDTHELSSKTMEAIKVPGLFFIGEVMDVSGWLGG----------FNFQWAWASVAAGKA....................... 390
9 -14.500PF13434.6; Q4K9A7_PSEF5/9-357; L-lysine 6-monooxygenase (NADPH-requiring)  ali follow..  10  4..DLIGIGFGPSNLALAIALEERGQDALFLDKQADYRWHGNTLVTQSEL-----QISFLKDLVTLRNPTSPYSFVNY----------------------------KHHGRLVDFINLGTFYPCRMEFNDYLRWVAGHFQEHSRYGEEVLAIEPVLHNQQVEASRDAQGSELVRTTRSVVVSAGGTARV--------------------------------------------------------------------------------------------ETFKGLKGDARVFHHSQYRMASQPCVSGKPMNIAIIG---------GG---QSAAEAFIDLN-QADIIMRGSA....................... 235
10 -13.700PF06100.11; G8PAJ4_PEDCP/22-520; MCRA family  ali follow..  10  1QKSAYLVGSGLASLAAATFLVRDGDRIHVLEELGLPGGSMDGIPHFETLWDLFRSIPSLENELSRKAINEIIKVALTPEDQLQDKQIDEVFSQEFFDSNFWLYWSTMFAFEPWASALEMRRYYESLIIP-MVKFLESKGVHFQYNTTVDNILVNRVGTGKVATKLEMTVDGKHESKKLTADDLVFVTNGSITESTTYGDNTHAAPVEHELGATWQLWKNLAAQDPDFGHPEKFYDNIPDANWTISGTITKDSNWLLGYSISRQDKKITECTGIELCEEWLYHIGVPEDQIVDIATNSASTIPAHMPYITSVNLAFIGNFA-------------------ETERDTVFTTEYSVRTAMEAVY............... 499
11 -13.300PF01946.17; THI4_SCHPO/60-299; Thi4 family  ali follow..  15  17ESDIVIVGAGSAGLTAAYYIGTRDLKIAIIEASVAPGGGAWLGGVRKPADLFLNEIGVPYEDEGDYVVVKHAALFT------------------------------STVMARTLALPNVKLFNATAVEDLIVKEGKDGKQRIA------GVVTNWTLVSLNHGLQSCMDPNTINAHLVVSATGHDGPFGAFC........................................................................................................................................................................................ 181
12 -12.600PF13738.6; E4RQY1_LEAB4/3-286; Pyridine nucleotide-disulphide oxidoreductase  ali follow..  15  1....VIIGGGPIGMACGIECKKAGLDYVILEKGCLVNSLYH----YPTTMTFFSTSERLE-------------------------------------------------------VSNSAKPTRAEALEYYRRVAQNQQLNIHLFEEVSDVYKVEKGFEVKTSKR------TYSAEKVILATGFYDIPNL---LGIPGEDLKVKHYYKD-----------------------------------------------------------------------------------------------PHFYAFQKIVVIG------------ANNSAVDVALETFRKGADVTMVIRDGEIGRTVKYWVRPDIENRIAEG 203
13 -10.700PF00890.24; Q8EJR4_SHEON/7-411; FAD binding domain  ali follow..  11  1..DSLVVGAGLAGLRVAIASKERGLDTLVLSLIPAKRSHSAAA--DQEVARMFAHCAAVRELANWGVPWSRVSAGPREVIVNAQKVTLQEAEEAHGLINARDFGGTKKWRTCYTADGTGHSLLY-----AMDNKAISMDIPVHERVEALALIHDGERCHVVARCLISGELRAYVAKSTTIATGGYGRI---YEVSTNAIICEGIGQALALETGVATLGNMEAVQFH-IVPVGILTTEGCRGDGGLLRDKDGYRFMPDYEPEKKELASRDVVSRRMTEHMRKGKGVDSLWLDITLLGRKHIETNLREVQEICENFLGIDTQHYS--MGGIGESPQLKGLFSVGEAACWDMHGFGGNSL................... 405
14 -9.620PF13450.6; B4RE46_PHEZH/425-493; NAD(P)-binding Rossmann-like domain  ali follow..  25  1.....IVGAGFAGSVLAERLTSQGKRVLLVDRRPHVG--GNAYDEKDAGGVLMHKYG............................................................................................................................................................................................................................................................................................................................... 51
15 -9.320PF02558.16; Q9K9R6_BACHD/6-154; Ketopantoate reductase PanE/ApbA  ali follow..  18  1...VAVIGSGSIGLLLYAYLKLANWPALLVTNRPEQADHLNKEGLTFVAKS..................................................................................................................................................................................................................................................................................................................................... 48
16 -9.240PF00743.19; FMO1_HUMAN/2-532; Flavin-binding monooxygenase-like  ali follow..  10  4...VAIVGAGVSGLASIKCCLEEGLEPTCFERSDDASLYKSVVSNSCKEMSCYSDFPFPEDYPN--------------------------------------------------------YVPNSQFLEYLKMYANHFDLHIQFKTKVCSVTKCSDSAVSEVVTMHEEKQESAIFDAVMVCTGFLTNPYLPL--SFPGINAFKGQYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQNMLRNSLPTPIVTWLMERKINNWLNDELPGRIITGKVFIRPSIKEV------KENSVIFNNTSKEE-PIDIIV-------FATGYTFA............ 333

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 2 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.