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Query: PF01602.20; Q22601_CAEEL/28-590; Adaptin N terminal region, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst ELKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGNDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLIEQQSDLMKLIVQGIRNDLTSRNPVHVNLALQCISNMGSREMVEAFCTDLPKLLVSGETIDFVKQSAALCILKLFRNSPDSFQPGDYASRIVHLLNDSHMGVVTSAASLIEALSKKWPEEYKGAVPLAISRLSRIVTATYTDLQDYTYYFVPAPWLCVKLLRLLQNYPPPDDPSNKARLLECLEGILNKAQDAPKSKKVQHSNAKNAVLFEAIALIIHMDSEPQLLVRACNQLGTFLSHRETNLRYLALESMCLLATSEFSHDAVKKHQDTIINSLKTERDVSVRQRAVDLLYAMCDRSNANQIVAEMLAYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILKLIRIAGDYVSEEVWYRVIQIVVNREDVQGYAAKTVFEALQRPACHENMVKVGGYILGEFGNFIAGDERSTAKIQFELLHSKFHLCSITTRCLLLTTYIKFCNLFPEIKPLVQQVFQTDHNLRNPDAELQQRSIEYLQMTKLASLast
1 -152.000PF01602.20; Q22601_CAEEL/28-590; Adaptin N terminal region  ali  100  1ELKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGNDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLIEQQSDLMKLIVQGIRNDLTSRNPVHVNLALQCISNMGSREMVEAFCTDLPKLLVSGETIDFVKQSAALCILKLFRNSPDSFQPGDYASRIVHLLNDSHMGVVTSAASLIEALSKKWPEEYKGAVPLAISRLSRIVTATYTDLQDYTYYFVPAPWLCVKLLRLLQNYPPPDDPSNKARLLECLEGILNKAQDAPKSKKVQHSNAKNAVLFEAIALIIHMDSEPQLLVRACNQLGTFLSHRETNLRYLALESMCLLATSEFSHDAVKKHQDTIINSLKTERDVSVRQRAVDLLYAMCDRSNANQIVAEMLAYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILKLIRIAGDYVSEEVWYRVIQIVVNREDVQGYAAKTVFEALQRPACHENMVKVGGYILGEFGNFIAGDERSTAKIQFELLHSKFHLCSITTRCLLLTTYIKFCNLFPEIKPLVQQVFQTDHNLRNPDAELQQRSIEYLQMTKLAS 563
2 -40.400PF12717.7; G8Y240_PICSO/105-271; non-SMC mitotic condensation complex subunit 1  ali follow..  17  1.................................................................................................LIRALAIRTMGCVRVARMVDFIEIPLKRTL--SDDNPYVRKTAAICVAKLFDLSPKACVEFGFLDQLRGLIKDSNPMVVANALNSLFEIKDMNVDSSLVVLEFDSELIKTLL----------MCLNECTEWGRITILDTLTKYEASSSEEASHIIDRATPQL---------------QHANPSVVLSSIKVILH................................................................................................................................................................................................................................................................................ 167
3 -17.300PF10508.9; A7SP09_NEMVE/2-505; Proteasome non-ATPase 26S subunit  ali follow..  13  7.................................................ELVENISNASGDEIVAFLRDLSVLISSSPNIRDLASERLFNCLRTTNTDQITYCKNILKNILKFEKPDAPATKYHDAVGLNHPTEDVRELCLIELERCSGTVNGLMDKEDLLSYIARGMADEHLKNAQIASNVFTNLAKHEAGLKVLFDSHLQSEFNALLKTKDTVRMRISELDGRDVLVQMNCLELLTKLASISPSGLEYLDQKGVVTKLNNLLLEVETDPLITLIIPGIIKFFGTLATAHPLETTQQYPQFLEQTYSMISCGDPTLMPIAMETIGVIAHSEDGLRAVFNNQGRNKHIMKTSSQVDLRKRALEALASIFYSEQLTPPLEAIFTVAKQPFEELRCSALCLLRSLARQDMINCPGFLEYLLDRRTEFEKSGKEHKYDLIKELVHFPPAFDRPYFLRLQEYEREGPFFARAEAAVAFEGAD..................................................................................... 504
4 -16.600PF05804.12; KIFA3_HUMAN/13-720; Kinesin-associated protein (KAP)  ali follow..  9  73KLNEVEQLLYYLQNRRDSLSGKEKKEKSSKPKDPPPFEGMEIDANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLLNRVLREDWKQSVELATNIIYIFFCFSSFSQFHGLITHCMNIIDHELKRHELWQEELSKKKKAVDEDPELRKDYEKTFKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRD-------------NFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMI-----------PCEHEDLLNITLRLLLNLSFDTGLRNKLLPKLTALLGND--NYKQIAMCVLYHISMDDRFKSMFAYTDCILMKMLFECSDERIDLELISFCINLAANKRNVQLICELMKRALKFKDPLLMKMIRNISQHDGPTKNLFI-VGDLAAQISNDEEEEFVIECLGTLANLTIPDLDWEL-LVPYLKDKLKPGAAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAEDDEFVCQIIYVFYQMVFHQATRDVIIKEPAYLIDLMHDKNNEIRKVCDNTLDIIAEYD 652
5 -13.000PF17741.1; A0A151PBS4_ALLMI/1-268; Family of unknown function (DUF5578 topsan)  ali follow..  9  2........................................................................................................................................................TSAKEQAAIGRLLAFLQEWDNAGRAARSRILDNFIEANQGKMGPELELEFSQGASLFLARLTAWLRLSYMNGTCLDQLLKAIGIFLSAASGHRYLIE---------------------------LEVGGVLTLLEILGLSQLKEEDKKESIKLLQLVANAGRKYKELIGVRSI--------------------AEFMASSKSEKAQRQVQILLDSLGNPKYQNQVYKGLIALLPCTSPHAQQLSLQTLRVVQAIVGKSHPSIVEAVLGVLRSMELEVQYEAIQLIKDLTSY--DVRPALLRGLVALLK....................................................................................................... 267
6 -12.900PF05918.11; D7TJH2_VITVI/11-547; Apoptosis inhibitory protein 5 (API5)  ali follow..  10  2......EKLYEYGERLNEAKDKS--QNVEDYRGII-------------------AAKGSIKAKQLAAQLIPRFFKFFPDLSDAAVDSHLDLCEEEELGVRVQAIRGLPLFDTPEYVSKIVDILAQLLTAEENV--ERDAVHKALLSLLRQDVKASLTGLFKHIMTVDDPSTDENLREKVLNFIRDKVFPLKAELLKPQEQMERHITNLIKKSLEDVTGAEF----------MFMDFLRSLTLFGEKAPPERVQELIEIIEGQADLDAQFNVSDGDHIDRLILYMALPFFVRGASNSKFLNYLNKHIIPVFDKLPEERKLDLLKNLAESSPY---------------------------------SAPQDSRQILPSVVQLLKKYMPRRGEETNFTYVECLLYTFHHLAYKAPNATNSLCGYKIVTGQPSDREYYKDFTERLTHVEELARATMKKLTQGMAEHNKAMAAAKS............................................................................................ 414
7 -11.700PF04931.13; K2SXE2_MACPH/89-879; DNA polymerase phi  ali follow..  9  1............................KAIVRLI-----G-------------LNSGR-KAARFGFVALTETLRQLYGSSSKLVKLVAELTQEKRDYLLGRVFGYKAIIQSSILVECWANVLEQLFKLAREKPWLREECGMILCEAVKAIAQEKGQQRLVKQIVDGLCSDGLAKTPEGVSVWITVQREIPDM-TKDRQTLANVMKENFTKTSDGANETGKKVKGSSQSWDVVISAFFQRHGDDPSRFANFWADIVDNNLFS-----ASSSPEQKSKGLQLFTRMLGNAPKWALPSIFSPNLMRCLINQRNDSERFLHNAAKAPLDEMRTRSKKEPETAAPFLENLITKHGS-DQITKNKTVEGVLGHANDVALEQIVPLFKRLIYRPEEQ-RRTVADMVVSAVRSRNGNDSWLREVLVGLTELARNMFQGRLTSCLAHLLSSKLDTEMDYPYIVVSAIRSKSKSSKSLSLVFQADKGISKAVKQAHKQVEEITEKLLKAKDKKKPAAFKLLFSLTIVQVYNGDPDAVSILEELAVCYESAFQKGADKSAFQLLTEVLLSF.. 593
8 -11.600PF04826.13; ARMX3_MOUSE/110-363; Armadillo-like  ali follow..  10  14.............................................................................................................................................................................................................................................................................................................LQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVDDTVTSRLNSSVQLAGLRLLTNMTNEYQHILANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMLRAQVPSSLGSLFNKKEYKEVILKLLI-IFENINDNFKWEENEPAQ-----------------NHFSEGSLFFFLKEFQVCADKVLGI------ESRHDFQVRVKV........... 253
9 -11.100PF13646.6; C3YB05_BRAFL/324-412; HEAT repeats  ali follow..  12  4..................................................LKKLLVDEDPNIRAVASIALGKTGTCTPD----IVEALVNLLKDEDRLVRESTCVSLGYLQAQDAVPHVINAWR-----NDPISHVREAAQAAL................................................................................................................................................................................................................................................................................................................................................................................................................................... 88
10 -9.510PF12755.7; C4QYN7_KOMPG/59-156; Vacuolar 14 Fab1-binding region  ali follow..  13  8.....................................................................................................IGLAATAIALGQHEVPKYLEKIIHPVCFGDQDARVRYYACESLYNISKVAKGEILLNEIFDNLCKLTADSEVSVKKGADLL............................................................................................................................................................................................................................................................................................................................................................................................. 92
11 -9.190PF12231.8; Q5BCS0_EMENI/131-504; Rap1-interacting factor 1 N terminal  ali follow..  10  1......................................................LAGESTSSRIDAYMQFFGALRAYEKLMSLIAEFIQRDISRDLT-LVIQALKLSVVL-PDEFKLFLIEHSVVCLESENLPKSVVTHYLTVLST--QKFPARIITAARTTRILGMLHSKGNSVISQRLMIYERLFDVAKPTFLALISGLLHQIKNVRLNALELGFNVYMASGSNSTLSKTLRDIFDRPLANNRKLVSEVSERMSRMMSNPETGEHVPQI--------GVITLLLRSKRFNIDQWQHFKEWVLVLQKCFNCNDPEIKSKAIGNWNRFV.......................................................................................................................................................................................................................................... 304
12 -9.140PF16782.5; J8Q2G5_SACAR/122-421; Nucleotide exchange factor SIL1  ali follow..  9  1DDYEFSNDFKEIRSIFDSHSTLSSHDITVLEDKFDNVMEFAHDYKHGYLANVSLNENLSLTLRELSTRVITSCMRNNPPVVILALSNLNDSNHKFSNILIKRYLSILNELPVTSLPIYSTINLQNVYQRNGKDKQLQIKVLELISKILKTGVWSPDLQEWANEFQAMAQDKDELHMRTFFDTLYNLKSIFKSDITINKAFLNWLAQQCKERQSNLDNGLHERDIEQDTFDKKLINSRHLIFGNPMAHRLKNFRDEL................................................................................................................................................................................................................................................................................................................... 300
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.