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Query: PF01695.17; Y4IQ_SINFN/60-238; IstB-like ATP binding protein, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst HRRIERHLAEAHLPPGKTLESFAFDAVPMVSKAQVMAIAAGDSWLAKGANILLFGPPGGGKSHLAAAIGLALIENGWRVLFTRTTDLVQKLQVARRELQLESAIAKLDKFDLLILDDLAYVTKDQAETSVLFELISARYERRSIMITANQPFGEWNRVFPDPAMTLAAVDRLVHHATIFLast
1 -89.400PF01695.17; Y4IQ_SINFN/60-238; IstB-like ATP binding protein  ali  100  1HRRIERHLAEAHLPPGKTLESFAFDAVPMVSKAQVMAIAAGDSWLAKGANILLFGPPGGGKSHLAAAIGLALIENGWRVLFTRTTDLVQKLQVARRELQLESAIAKLDKFDLLILDDLAYVTKDQAETSVLFELISARYERRSIMITANQPFGEWNRVFPDPAMTLAAVDRLVHHATIF 179
2 -21.800PF00308.18; DNAA_STRCO/317-535; Bacterial dnaA protein  ali follow..  20  1............LNPKYLFDTFVIGASNRFAHAAAVAVAEAPA--KAYNPLFIYGESGLGKTHLLHAIGHYARSLGTRVRYVSSEEFTNEFINSIRDGKGDSFRKRYREMDILLVDDIQFLADKESTQEEFFHTFNTLHNNKQIVLSSDRPPKQ----------LVTLEDRLRNR.... 154
3 -16.500PF00910.22; A7M6L1_9SECO/473-576; RNA helicase  ali follow..  12  1..................................................VYAYGESRTGKTLVVDKLITDFQNH-----------FGLGKDTVYSRNPIDQYWSGYRRQPIVSIDDFGAVTCDPSMEAQMIPLVSSMFDSKFIFCSSNL............................. 104
4 -15.100PF05496.12; RUVB_BACAN/21-179; Holliday junction DNA helicase RuvB P-loop domain  ali follow..  17  8......................QYIGQDKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEM----------GVNVRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSIEEVDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGALSAPLRDRF....... 153
5 -14.800PF07652.14; Q32ZD8_9FLAV/1675-1822; Flavivirus DEAD domain  ali follow..  14  1............................................FKKKQLIVLDPHPGAGKT-VLPEFIRQAVERRLWTLALAPTRVVKEIVDLMCHATFTMRLLSVPNYNMFIMDEAHFTDPSSIAARGYISTKVDMGEASAVFMTATPPGSREPFPDSNA................. 148
6 -13.800PF03266.15; NTPTH_METAC/3-167; NTPase  ali follow..  19  1.................................................RIAVTGSPGVGKSTVVAKTAEKLAEKGFKIGGIRTAEIRKEVNLDDLERIGANAVRNALACDLVVIDEIGPMELISQSVSAVEEVLESDKPVLAVLHHSSRH............................ 137
7 -13.600PF06745.13; O29463_ARCFU/20-274; KaiC  ali follow..  19  29............................................IPHLAVMNITGVPDTGKSLLAEQFAITQAGSGYRVLYVTVESPANFLYTAMKEETMAYAIKEK-KVTNTIIDSITYEHKEMMARQIVRQFFNFMKKYRTGIFVSQKRSAQ-SAEAAGGLAVAHIVDGTI...... 196
8 -13.500PF04665.12; Q6TUP8_YMTV5/6-246; Poxvirus A32 protein  ali follow..  17  7.........................................KSLLKHPFRIALVGGSGSGKTAYLLSLFNTFVEKYRHIFLFTPVYSLITTKQKIEKYVKKQGNDKTTEMFLLILDDMGDKQIRSSCLLDFLN--HGRHLNTSIILLCQ.............................. 136
9 -13.400PF05673.13; Q0K6N5_CUPNH/29-287; Protein of unknown function (DUF815 topsan)  ali follow..  22  17........NIGYLQPVRQLPPIHLDDLKNIERQKDAIVANTRQFVSKANNVLLTGARGTGKSSLIKACLNAFVRDGLRLVEVDKDDL-------GDLGDIVELVAQRPERFVIFCDDLSFEEGESGYKSLKSALVAAQSDNVLIYATSN.............................. 155
10 -13.400PF12775.7; A0A0L8HIS0_OCTBM/1630-1811; P-loop containing dynein motor region  ali follow..  15  26........................................LNLSIEQNMPILFVGPTGTGKSSYVQDKLMKGISKELNFSAQTSANQVQTIIMTSLAKRRRGVFPLIGKTAIIFVDDMNMPAKEVYGAQPPIELLRQFFDHGHWYDLKDTSKLILKDIQFLAAMGCDVTPRFLRHFNIV 177
11 -13.100PF13337.6; R6V945_9CLOT/51-507; Putative ATP-dependent Lon protease  ali follow..  14  179..................LRSIGMEPDTLSYREKWLLLARMLPLVENNFNLCELGPRSTGKSHIFKEISPNSILVS-----TTVANLFYNMGRKTVG---------VGLWDCVAFDEVAGINFKDKDGQIMKDYMASGSASASMVFVGNINQSVFDPFPPEMGTDTAFLDRM....... 341
12 -12.500PF07728.14; Q82S33_NITEU/475-632; AAA domain (dynein-related subfamily)  ali follow..  20  1.................................................NLILQGPPGTGKTWLAKRLAFALMGQKDDVQFHPNLSYEDFVRGWRPTGEGKAASKDPSSKFVVVIEEINRGNPAQIFGELLT-LLEAGKRTPNEALELCYPDADGKRTMNIADRSLALVDLALRR.... 156
13 -12.300PF01443.18; RDRP_TMV/829-1085; Viral (Superfamily 1) RNA helicase  ali follow..  10  1..................................................VLVDGVPGCGKTKEIL----SRVNFDEDLILVPGKQAAEMIRRRANSSGMNFGKSTRCQFKRLFIDEGLMLHTG------CVNFLVAMSLCEIAYVYGD.............................. 105
14 -12.000PF13479.6; F5YIK8_TREPZ/11-202; AAA domain  ali follow..  16  4.................................................RCALFGPSGSGKTMTALRMAKGIADTGVPFAVIDTEARSASKYADRIPDHYIAAMNECVKYKVLVIDSL----------SHAWRELTDEVDRIAQSSVSKNTFSPWAKV---NPKQKRFIDAILNFPGHI 134
15 -12.000PF00004.29; LON_BRECH/351-493; ATPase family associated with various cellular activities (AAA)  ali follow..  19  1..................................................LCLVGPPGVGKTSLARSVARALGREFVRISLGGVRDEAERTYVGALPGRIIQGMKQAGTINVFLLDEIDKLASDFRGASALLEVLDPNQNDKFSDHYIEETYDLTNVMF--DTIPRPLLDRM....... 135
16 -11.900PF02572.15; R5BPN3_9FIRM/40-219; ATP:corrinoid adenosyltransferase BtuR/CobO/CobP  ali follow..  27  5..................................................ILVNTGDGKGKTTASLGVALRAVGNGYRVLILQFADLQAHRAAADNAWQMLTEEVMSDKWDLIIFDEINYVKFGLLPVEQVVDLLKTKPERLHVVLTGR.............................. 145
17 -11.800PF13173.6; F9Z5R0_ODOSD/18-152; AAA domain  ali follow..  13  1...............................................RKPLILNGARQVGKTWLLHEFAKLEYKKEAYVVCRKNNLARQLFSQDFNVDRILRGLRAMTSVDLIILDEIQDIP----EALESLKYFKEEVPEYHIAVAGSL............................. 105
18 -11.800PF13604.6; Q3L956_RHOE4/579-769; AAA domain  ali follow..  14  6..............................QIAMIEHFLTAKTKVA-----VAVGAAGAGKTTAAKVVARAWEQTNGKVIALGPSAKAADVLGAEIDVEGRTIADGIEKGDLLLVDEAGMA-----SARNLADLTRIATQSGAVVR-----------LLGDPLQLASV........... 133
19 -11.700PF07726.11; Q87G66_VIBPA/36-166; ATPase family associated with various cellular activities (AAA)  ali follow..  15  1.................................................HILVEGPPGLAKTRAVKSLSDCVEGDFHRIQFTPLPADLTGTDIFRPETGEFTFQSGPIFNSLILADEINRAPAKVQAA--MLEAMAEKQPELFLVMATQNPIEQ-----GTYPLPEAQLDRFL...... 130
20 -11.700PF01637.18; A8M939_CALMQ/15-228; ATPase domain predominantly from Archaea  ali follow..  17  6...................................VAIRQIEKLAEKGTWVVIYGPEGCGKSAFLKQAVEVLGEYDYSVVKVSPLEDESNEKLRYSEELRGLFRDIMTRIPALLADDVFQAIGLDKAELLVKRLLNSVDYERIVVIVATSEGVTWGRIGRHRWAEIMAMWNM....... 178
21 -11.600PF07724.14; Q7PAG5_RICSI/595-759; AAA domain (Cdc48 subfamily)  ali follow..  15  5.................................................SFLFLGPTGVGKTELTKALAGFLFDDRNAILRIDMSEYMEKHAISRDQGGVLTEAVRRRPYQVILFDEV--EKAHPDIFNIMLQILDE-FKNTIIVLTSNL............................. 125
22 -11.300PF13238.6; A0B5Y2_METTP/3-117; AAA domain  ali follow..  12  1..................................................IALTGTPGTGKTTVSGLLPFRVVNLNDLIR-ALEEKIEEIERSCGDDVLIIEGHFAHHFADEAIV-------LRLHPNVLRRRLEARGYSASKI----------------RENVEAEAID......... 115
23 -11.100PF07088.11; GVPD1_HALSA/23-536; GvpD gas vesicle protein  ali follow..  15  7............................................GDAGETLLINGAPGTGKTLFTIRG-LDVLDRDSDVLYVSTRVDQETVHEPFEKLDLDSLLEWIQTQLTIAFDSWELIY-DPPDIKTVTNQLAVLAREERLMLVTETAAPSSLEYIVDGVVT.............. 171
24 -11.100PF08433.10; O46079_DROME/1-293; Chromatin associated protein KTI12  ali follow..  22  4..................................................VVITGLPASGKSTRARQLRDHFVERGRKVHLISENEAVPKAGFGKNSHTKSEASRHLNQEDLVILDAGNYIKGYRYE----LYCMSKVSRTTQCTVFTCIPQEE......................... 116
25 -10.700PF14532.6; C6X8G9_METGS/136-273; Sigma-54 interaction domain  ali follow..  11  2............................GKSPVISELRQRLEQIAGVKSPLLLIGEQGSGAELCAKFL-------------HNPDTPWLSLTDYEQLATAPLDILEQVQEGMLFIPEVADLSKNQQKG--LQLLLARADKYGARVVCVT---KSLPQLVVAGRFDNLLLQSI....... 128
26 -10.600PF09439.10; SRPB_YEAST/36-221; Signal recognition particle receptor beta subunit  ali follow..  16  1.............................................SYQPSIIIAGPQNSGKTSLLTLLTTDSVRPTVVSQ-VTLVDFPGHVKLRYKLSDYLKTRAKFVKGLIFMVDSTVDPKKLTTTAEFLVDILSICENGIDILIACNK............................. 120
27 -10.500PF00154.21; RECA_ACIAD/7-268; recA bacterial DNA recombination protein  ali follow..  18  1.....KALQAALSQIEKQFGKNTVMRLGDNTVQAVEAVSTGSLTLDKGRIVEIYGPESSGKTTMTLQAIAQCQKAGGTCAFIDAEHLVSQPDHGEQALEIADMLVRSGAIDLIVVDSVAALTPKAE-SQALRKITGNAKRSNCMVIFINQIRMKIGVMFGSPETTTG............ 204
28 -10.500PF02562.16; A0LK93_SYNFM/124-328; PhoH-like protein  ali follow..  14  16............................................IRHYDIVFGVGPAGTGKTYLAMAMAVAAMTKDLVRRIVLVRPAVEA-KLGFLPGDLAEKVNPYLRPLYDALHDMDFERATGLLQRGAIEVAPLAFMRGRTLNDAFVILDEAQNTTTEQM--KMFLTRLGLGSKAV 150
29 -10.400PF13177.6; A5VIC8_LACRD/13-171; DNA polymerase III, delta subunit  ali follow..  19  1..............................QPAIITRFQKILSNNELAHAYLFVGPGGSGKMSIAQWLSLRLCAECQRILSGNHPDIVYKVDEIRRLKAEFSKSAVEGNKKIFIIKDA---KMTNGAANSLLKFIEEPGAGVYIFMLTTNK----------SAVLPTIRSR........ 150
30 -10.300PF08303.11; Q6CK12_KLULA/389-554; tRNA ligase kinase domain  ali follow..  14  2..................................................LVTIATIGCGKSTVSLTLNELFPESWGLVV--------DNITSNKTDYIKSALQLFKDGKQFVLADKNNH---QFRERAAVFEWINQYRDSYIPYNCNLQVIALCFVDEVSPEMRALTIDRVMKRGD.. 118
31 -10.100PF02374.15; ASNA_HUMAN/37-340; Anion-transporting ATPase  ali follow..  17  4..................................................IFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDEIDPSLGVAELPDEFFEEDNMLSMGKKMMQEAMSAFPGIDEAMSYVMRLVKG--MNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLM...... 155
32 -9.980PF17213.3; F6ZLU4_XENTR/1991-2193; Hydin Adenylate kinase-like domain  ali follow..  18  2..................................................IIVHGAPLTGKSSAAVTLA-----QHYNIPCLSIDSVVLDAISDSNSPTGMRARQLCSK...................................................................... 55
33 -9.970PF02399.15; OBP_VZVD/13-828; Origin of replication binding protein  ali follow..  17  46.............................................QTRPVTVVRAPMGSGKTTALLEWLQHALKADISVLVVSRRSFTQTLIQRFNDAGLSGFVEAIDSYDVLILDEV-LYSPTMRRLSAVDSLLYRLLNRCSQIIAM------------DATVNSQFIDLI....... 193
34 -9.940PF01591.18; F262_BOVIN/27-250; 6-phosphofructo-2-kinase  ali follow..  16  16..................................................IVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRRQAVKSYKSYDFEEAMKIRKQCALVALKDVKAYLTEESGQIAVFDATNTTRERRDLILN................................ 117
35 -9.780PF03969.16; ZAPE_ECOLI/4-371; AFG1-like ATPase  ali follow..  22  69................................................RGLYMWGGVGRGKTWLMDLFYQSLGERKQRLHFHRMLRVHEELTALQGQTDPLEIIADKAETDVLCFDEFFVSDIT--DAMLLGGLMKALFARGITLVTSNIPPDELYRNGLQRARFLPAIDAIKQHCDVM 202
36 -9.760PF05894.12; A0A0G0ERS5_9BACT/5-334; Podovirus DNA encapsidation protein (Gp16)  ali follow..  16  1.............................LTKDIWYDINRL--LSFKALISVVVGMRGGGKTYAKKRCIIDFKEKGQQFVWLRKKTFFNAIRNIALTLAHKFKSSDFPLVVNIVYDELGYLRSEVTALYNLIETIQRQRDTTRVIMIAN.............................. 166
37 -9.760PF06068.13; RUVB2_CAEEL/17-361; TIP49 P-loop domain  ali follow..  14  25......................GMVGQVAARQAAGLIVKMIQEGKIAGRALLVTGEPGAGKTAIAIAISKEL---GEDTPFVSIVASEIYSNEINKTEALTQAFRR--ALGIQIKEETEVLEGEVISLEVDRSANGMGPKVGKLTMRT............................... 145
38 -9.750PF09897.9; U6EA19_9EURY/8-147; Uncharacterized protein conserved in archaea (DUF2124 topsan)  ali follow..  10  7.....................................LMAFKKEVENAEKVTFVGIPGV--SPFALLFAHVI--RDKESVFVSRTDLASAHKIERTPLGMQFTEEADPHSSVVALMGGLSMPQYKVDVVDVQKMLDEILLPGGKILMNMFENAGWDDKIDFDCIINGILT......... 140
39 -9.610PF13401.6; B2UJB3_RALPJ/42-210; AAA domain  ali follow..  16  2.............................................SQESILLVCGPTGAGKTTLAKFMVENAHSQ-IPAIYVQAPRILNQLGDDLDSPKVAYGVDSLSQVQFMVIDEAAHIFRDTQRNSKLEVQLD........................................... 144
40 -9.540PF00265.18; KITH_MYXVL/6-176; Thymidine kinase  ali follow..  10  5...................................................LIIGPMFAGKSTELIRLVKRYQIARYKCLVVKVRTHDNTCISAVPTASLDDVESISEHVEVIGIDEGQFF-------PNIVSFCERMANAGKVLIVAALDGTFQRKPFTNICELIPLAENVTK..... 130
41 -9.390PF00158.26; Q8E8E7_SHEON/154-320; Sigma-54 interaction domain  ali follow..  15  5..............................SDAMKSVKQVIERVAPTNAVVLIQGESGTGKELVARQLHLLSGRQGPFVPVNCGSELLESELFGHTAGAFTGAKGSFASGGTIFLDEIGEMPLKMQTA--LLRVLEQKAIRPRVIAATNRTLVD......................... 146
42 -9.370PF06431.11; Q8JUD5_POVJC/266-682; Polyomavirus large T antigen C-terminus  ali follow..  15  152............................................IPKKRYWLFKGPIDSGKTTLAAALLDLC---------------GKSLNVNMPLERSNFELGVGIDQFMVVFEDIKGTGAESRDLDCLRDYLDRTQVFPPGIVTMN.............................. 265
43 -9.370PF05729.12; G3V6C0_RAT/441-610; NACHT domain  ali follow..  18  2..................................................VAVLGKAGQGKSHWARTVSHIWAQGQLPQYDFVFYVPCQCLDRPGDTYHLRDLLCPPNLQPLLILDAFEELEAQDSLLHLLAGLFQRKLLRGCTLLLTARP............................ 135
44 -9.350PF13245.6; B1YJE6_EXIS2/332-475; AAA domain  ali follow..  17  14..................................................MVLTGGPGTGKTTVIKGI-LQEIHDWPLEKSQVKSGEVYPYVLVAPTGRAAKRLSEATAGKVLIIDESSMIDI-----YLLSSLLRAVPNGMKILFVGD.............................. 135
45 -9.230PF13521.6; A4CIV1_ROBBH/14-173; AAA domain  ali follow..  15  1.................................................KVVLFGPESTGKTTLARELARHY---GEPWVPEYAREYLQEKWDRVQQTCAPEDLLPIARGQMLICDTYSETYYGGGCDPKLQAAALANDYDLYFLTDIDIPWEA......................... 122
46 -9.190PF06309.11; O45271_CAEEL/5-130; Torsin  ali follow..  11  50.............................................QKPLVLSFHGGPGTGKNYVTEIIAKNTFRSGLQSPYVKYFVATKDFPNNKHIEDYKLKLKEQLIQSA................................................................... 116
47 -9.140PF03215.15; RAD24_YEAST/58-237; Rad17 P-loop domain  ali follow..  14  26...................................RKLKDVQEALDAMFLLLLSGPSGCSKSTVIKELSKIL---VPKYRQNSNGTSFRSTPNEHKVTEFGARYLVMSNLSLILIEDLPNV-FHIDTRRRFQQLILQEPLLPPLVICIT.............................. 167
48 -9.120PF01745.16; IPT_RHIRD/1-235; Isopentenyl transferase  ali follow..  18  4..................................................RLIFGPTCTGKTSTAIAL---AQQTGLPVLSLDRVQCCPQLST----GSGRPTVEELKGTTRLYLDDRPLVKITAKQAHERLIAEVHNHEAKGGLILEG----------GSISLLRCMAQSR....... 110
49 -9.110PF03481.13; R5ALB5_9CLOT/198-340; Putative GTP-binding controlling metal-binding  ali follow..  14  31.......................................................SPGMKYKHYAPKADVIVIVGTPENTAKKVCELYNFAEMQGKSVEIAATLQTKGFYKGKKYAILGDRNHPETLCASLFSSLRSMDEHADMILAEGIP---------TDNAGLAYMNRLLRAA... 142
50 -9.040PF04275.14; F8W4R0_DANRE/22-132; Phosphomevalonate kinase  ali follow..  12  1....................................................FSGKRKSGKDYVTDLIQKRLTAEICCI--LRLSAPLKEQYAKDHNLDYEELMGQYKESYRADMIHWG-EMKRQEDSGFFCRLAIKHATQPVWIISD............................... 95
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Schwarzenbacher R, Godzik A, Jaroszewski L. The JCSG MR pipeline: optimized alignments, multiple models and parallel searches. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):133-40. Epub 2007 Dec 5.