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Query: PF02058.15; GUC2A_CAVPO/20-107; Guanylin precursor, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .
# Score Template Links and tools%idFirst AVTVQDGDFSFSLESVKKLKDLQEAPESKVQGRRKFVAPPLCSFSGFPEELRPVCKEPNSQDILNRLAVIAQDPSTCEICAYAACAGCLast
1 -58.700PF02058.15; GUC2A_CAVPO/20-107; Guanylin precursor  ali  100  1AVTVQDGDFSFSLESVKKLKDLQEAPESKVQGRRKFVAPPLCSFSGFPEELRPVCKEPNSQDILNRLAVIAQDPSTCEICAYAACAGC 88
2 -7.510PF02048.16; HST_YERKR/20-66; Heat-stable enterotoxin ST  ali follow..  66  36............................................................................CEVCCNPACAGC 47
3 -6.680PF01485.21; Q7S3S6_NEUCR/125-184; IBR domain, a half RING-finger domain  ali follow..  22  15...................................................PLYCSNRQCGSFIKP-ALIKSDLGLCPKCFASTCKHC 50
4 -6.620PF16881.5; LIPA_SCHJY/7-112; N-terminal domain of lipoyl synthase of Radical_SAM family  ali follow..  18  38.............DFLKGDKEEQLKPEEAYELEENVVLPNGSVHKRLPSWLK---TKVPLGTNFNKIKNDLRGLNLHTVCEEARC... 106
5 -6.550PF17249.2; G0FZF0_AMYMS/1-131; Family of unknown function (DUF5318 topsan)  ali follow..  12  1.MINQRQVVDYALQRRALLAEV---------RSGRVGSYEACASPYLLRAAKPICRQEPLTLVSEELARMAGSFAEFTVYDVEVCRAC 106
6 -6.490PF02157.15; H3A4D2_LATCH/26-276; Mannose-6-phosphate receptor  ali follow..  10  65LVQIDKKNHETVVGRFSQTHLIGGSDWIMLIYEHGDEYKDHCNKEARKAMVMISCNEKTLGDAFTVVIEEREKNEDCELDSQVACP.. 154
7 -6.450PF14265.6; J9W709_LACBU/38-176; Domain of unknown function (DUF4355 topsan)  ali follow..  11  63...........RQALKEQQDRLQEKLDEADRKNALAATKTVLTDKHIPAEFAEFISDVKEDVRNNNLDKFTN................ 123
8 -6.200PF00377.18; PRND_SHEEP/63-178; Prion/Doppel alpha-helical domain  ali follow..  10  6.INFGVEGNRYYEANYWQFPDGIHYNGCSEANVTKEKFVTSCINATQVANQEELSREKQDNKLYQRVLWQLIR----ELCSIKHC... 85
9 -6.010PF05315.11; F4HDL7_GALAU/5-226; ICEA Protein  ali follow..  21  128..........................................INSQHIDDFQPLCKAAND-----------VKRQICKRCKETGCKGC 189
10 -6.000PF14949.6; H3IMN4_STRPU/15-120; ARF7 effector protein C-terminus  ali follow..  27  59.....................................................................SSTGQDLCD-CLGKDCPGC 76
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.