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Query: PF02826.19; Q98GE4_RHILO/107-283; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFTALALLRQFRRVDRDLRAKGWLAGREHANANIELAGKTIGIVGLGAVGQAVGHIAAHGFDLKVVATTRSMQPAPEKVGFLSIDALVEQSDIIVLCCPLTPETRGLISRERIARMKPNALLINVSRGPVVDDDALIEALREGRIGGAALDVFSTQPLSYNHPYFGFDNVIITPHMALast
1 -92.300PF02826.19; Q98GE4_RHILO/107-283; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain  ali  100  1MFTALALLRQFRRVDRDLRAKGWLAGREHANANIELAGKTIGIVGLGAVGQAVGHIAAHGFDLKVVATTRSMQPAPEKVGFLSIDALVEQSDIIVLCCPLTPETRGLISRERIARMKPNALLINVSRGPVVDDDALIEALREGRIGGAALDVFSTQPLSYNHPYFGFDNVIITPHMA 177
2 -70.500PF00389.30; Q9KCG9_BACHD/20-325; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain  ali follow..  36  100FAMICSLLRKIPQANASIKAGEWKRKA---FQGTELRGKTLGIIGFGRIGSQIAK-RAKAFEMTPYVFDPFLTKAKLGVTVASLDDVLQVADIITVHTPLTKETKGLLGMKNIGKTKKGVFLINCARGGIIDEEALKHYLREGHIAGAALDVFEEEP-VADEELLAFDNVIATPHIA 274
3 -31.000PF00670.21; SAHH_DICDI/191-351; S-adenosyl-L-homocysteine hydrolase, NAD binding domain  ali follow..  18  17...............................TDVMIAGKVAVVAGYGDVGKGCAQ-SLSKMGARVLVTEIDPQACMDGYQIVTMETAAPLSNIFVT----TTGCRDIVRGEHFAVMKEDAIVCNIGHFDCEIDVAWLNANAKKDTVKPQVDRYTLAN-GVHIILLAEGRLV...... 154
4 -14.900PF07991.12; ILVC_METAC/15-178; Acetohydroxy acid isomeroreductase, NADPH-binding domain  ali follow..  16  1...................................LKDKTIAIMGYGSQGHAHARNLHES-GLNVVVGLRKGSSESDGLKVMTVEEAAKAADVIMILLPDEKQASVYY--SQIEPSLEAGNALVFAHGFNIHYNQIVPPKDVDVFMVA............................. 115
5 -13.500PF05221.17; D9SB20_FIBSS/15-498; S-adenosyl-L-homocysteine hydrolase  ali follow..  26  251................................DVMMAGKIAVVCGYGDVGKGCAQ-SLRGQGARVIITECALQAAMEGYEVKTLDEVVSYADIFVT----TTGNTGIISAAQMEKMKNRAIVGNIGHF---DNEIDMAGLKK................................... 356
6 -11.700PF03446.15; Q8FTI1_COREF/15-184; NAD binding domain of 6-phosphogluconate dehydrogenase  ali follow..  12  2........................................IGVVGLAVMGSNLARNFARN-GHTVAVYNRSTDKTDKLISTKTVEDFVAALEKPRRAIVMVQAGAATDAVINADAMEEGDIIIDGGNALYTDTVCREKEMAARGRHFVGAGI......................... 124
7 -11.400PF10727.9; Q743Y6_MYCPA/8-128; Rossmann-like domain  ali follow..  16  6.......................................KVGIISAGRVGTALGVALERADHVVVACSAISHASRQRAQRRLTPPEVAAGAELLLLAVPDSELAGLVSGLAATEAVRAGTIVAHTS--GANGVGILAPLTRQGCIPLA............................. 118
8 -10.300PF01262.21; Q9S227_STRCO/141-353; Alanine dehydrogenase/PNT, C-terminal domain  ali follow..  15  25..................................GVLAGRAVVIGGGVSGWNAAQI-AIGLGFHVTLLDKDITKLREVSNAFELEKACLEADLVIGAVLIPGAAPKLVTNELVSRMKPGSVLVDIAQGGCF-EDSHPTTHAEPTFPVHNSVFYCVANMPGAVP.............. 166
9 -9.390PF13241.6; Q2FTK6_METHJ/4-113; Putative NAD(P)-binding  ali follow..  19  3.................................IDFTGKKVIIFGGGVIGARKARYFAYEADVLVYSRSFHPEPVRTEVCNLTGDLEILRNMIHDASLVIAATSDPELNELIESACAREHIWCNVAAGKRGD............................................. 105
10 -9.150PF16924.5; D3E6N7_GEOS4/7-123; Dipicolinate synthase subunit A N-terminal domain  ali follow..  10  1.......................................TVFVGGDARQIEVIRKCAEMDASVMIAGFEKLQDSFQGVTREPLTPELLSDADALILPVVGCDDEGRVLQEEHIAAMPGHGVIYTGMAKPYLRSLCDKYKIK.................................... 112
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.