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Query: PF02982.14; SCYD_MAGO7/10-169; Scytalone dehydratase, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160
# Score Template Links and tools%idFirst EITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETFLast
1 -95.400PF02982.14; SCYD_MAGO7/10-169; Scytalone dehydratase  ali  100  1EITFSDYLGLMTCVYEWADSYDSKDWDRLRKVIAPTLRIDYRSFLDKLWEAMPAEEFVGMVSSKQVLGDPTLRTQHFIGGTRWEKVSEDEVIGYHQLRVPHQRYKDTTMKEVTMKGHAHSANLHWYKKIDGVWKFAGLKPDIRWGEFDFDRIFEDGRETF 160
2 -57.400PF13577.6; E3J7S1_FRAIE/26-166; SnoaL-like domain  ali follow..  10  1.RELEDDRAIRDLLAHYGYTADTCKDEEFVELYTEDGRIKVAASAKARAAFETKDGVRDFITHPKGHHSPYGKSMHLQGNNLVTEIQGDEAVARGYQVAIVADDQGTR-------VLSAGNNQWQLRKVDGRWLIRERR..................... 141
3 -48.700PF12680.7; A2SP57_METPP/26-134; SnoaL-like domain  ali follow..  15  1.............VSGYALGWDRHDVNLLLSVFHEDAEYLMPGLFG---DFRGADEIRRVYDQ---VVVAIPETWHFTTNLLLK-VDGDRATGISEVNMHGTEASGRP-------IILAATYLDEFQRRAGRWAIS........................ 109
4 -29.700PF12893.7; Q2KDJ8_RHIEC/2-116; Putative lumazine-binding  ali follow..  17  1....SDRQAVEQTVHLYVEGMAFANAAALKKAFHPKSSII--GYYQNAVEWLTRDEFIAAILAEE---PAPPGTQPFMDIQNVD-VEGDAASVKVTDD------------------FAGMRFTDSLLKIEGRWVIVSKLYH................... 115
5 -25.500PF11533.8; Q7CK76_YERPE/32-154; Protein of unknown function (DUF3225 topsan)  ali follow..  6....AVLAEVTAAFYRYEQALIGNDIAVLDALFWHDKRT----RFGAGEDLYGIDAIREFRQNRPS-----VGLDRKLKNTVITTFGEDTAVASTEFY--------------REGSTRVGRQMQTWVKLPCGWRIVAAHVSL.................. 121
6 -25.000PF08332.10; F8WHB5_MOUSE/57-184; Calcium/calmodulin dependent protein kinase II association domain  ali follow..  1.....RKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTA---EPEALGNLVEGLDFHRFYFENLWSRNSKPVHTT--ILNPHIH-LMGDESACIAYIRITQYLDAGGIPRTAQ------SEETRVWHRRDGKWQIVH....................... 121
7 -22.600PF14534.6; D5SSM1_PLAL2/48-156; Domain of unknown function (DUF4440 topsan)  ali follow..  11  1.........LKASAAGFERAFNAGDAKAIAAQFTELAET----VDEEGNILEGRANIESRFAE---LFKDYPKAQIAVTLTSLRLISPDVAVEDGYSMTTLDPSQPGSR----------SPYAVVHLKRDGKWLM......................... 109
8 -21.900PF12707.7; Q46KI2_PROMT/2-129; Protein of unknown function (DUF3804 topsan)  ali follow..  15  1....SSKEEILSILEAFASTERMGS--FFLDNATADFL-----FIRPSGNPLDAKGFENMWSSGDLVLESAEITK----VHKFELLGSNAAICVFTLGSKFTYKGTQ--------NDDLPTVTSIFKKIDEKWKVAWMQRSTLWN............... 128
9 -19.700PF13474.6; Q12PU2_SHEDO/77-185; SnoaL-like domain  ali follow..  18  1.........INSLLNQLHESAMSADWDTYFDLYHPDAAF----IGTDATERWNMVHFRRYASPTQGWRYDLQARH---------LQIEDVVVFDEQLYSPE---------------YGISRGTGALVNTTKGWKIAQYHLSF.................. 106
10 -17.200PF00866.18; BPHE_PARXL/33-181; Ring hydroxylating beta subunit  ali follow..  1...............REAQLLDHRAYEAWFALLDKDIHYFMPLRTNRMIREGELEYIRKVTSDVGWAENPPSRTRHLVSNVIVKETATPDTFEVNSAFILYRNRLERQVDIFA------GERRDVLRRADNGFSIAKRTILLD................. 143
11 -15.600PF16111.5; A3DK62_CLOTH/603-727; Domain of unknown function (DUF4829 topsan)  ali follow..  1..........EQVIEEYFTALDKKNIEVAKRCISKKTLLES--TANMENSELFNESLVLPLAGGGIGAKSNFDNLKSAKLLKVELIEEPDKYTKIFRVTVDLKYKKEVILS-------NGKQDWDCETPQTGWRIEGF...................... 124
12 -13.800PF12870.7; Q7VHU7_HELHP/20-130; Domain of unknown function (DUF4878 topsan)  ali follow..  15  9..........KDVAIAFTKDAYKGNGDRLIKYIHLPQMETDAT----------KEIVKGKFKTAAAKAESKAEAFGGLDEVKAECIEEQRAIIKVFVRFKNGSVDTDT----------------ELIKVDNEWKV......................... 110
13 -12.200PF07080.11; G0A5W1_METMM/8-137; Protein of unknown function (DUF1348 topsan)  ali follow..  10  4.....TEETAAQKVRMAEDAWNSRDPDRVVQVYTENTIWRNRA-----EFPVGRKQVHAFLQRKWAKELDYRLIKELW------ATTGNRIAVRFAYE.............................................................. 85
14 -10.900PF07366.12; Q82M76_STRAW/10-135; SnoaL-like polyketide cyclase  ali follow..  11  1...........ALLRTAYQRLQSGDLDACVELLTENFIANVPGTPD---PLHGREIWRLGAQAMLEGFPDLQVDVEDM------FSVHDKVAVRVHFRGTHQGTFQGVAATHRPVGFRSIEL----------YRIEGDRIAEEWVAPDLMSLMQQ..... 125
15 -10.400PF16247.5; Q8YWM3_NOSS1/1-129; Domain of unknown function (DUF4904 topsan)  ali follow..  11  1....MDTEKYHEMLKTYFRSFETGDFSQV--QFSCHLEFL------SGNTFKGIEEVISFLKGVTTRVSEVNIMS--------TTVEYPRASGVWQMRTTK........................................................... 84
16 -10.400PF05223.11; Q8Y9T2_LISMO/44-163; NTF2-like N-terminal transpeptidase domain  ali follow..  13  3..........LAAAETFTSNIAKEKYDKLGGSVSSESLKKVE---------FTKKEMEDKYQAVYDGIGAKNIKVKNLKSVYDD--KENKFNLTYELEMRTSLGKLATQKYKT-----------TISKQDDDWKID-------W---KPALIFPGMVK.. 118
17 -10.300PF13355.6; K9Q5G5_9NOSO/652-765; Protein of unknown function (DUF4101 topsan)  ali follow..  2..........EEVIRTWLST-PNHDIESLTNILTGSSLSQWRLIAQQDRVDNRYRRYDHSVK---------------VEFVSKNDLDPNRAAVLATVKEATQFYENGQKKKSSSESL---RVRYDLIRREGTWRIQ........................ 114
18 -9.880PF16156.5; K9VG60_9CYAN/11-111; Domain of unknown function (DUF4864 topsan)  ali follow..  13  1.........IRSVVEQQLQAFQKDDAAGAFAFASPGIQQQFR----------TAENFMHMVKISVLFENLATVEGIPAQPVLLLDSEGIPIRAIYLME----------------------------KQFDNSWRINGC...................... 100
19 -9.690PF03284.13; C5AHF3_BURGB/12-165; Phenazine biosynthesis protein A/B  ali follow..  9......RQHNRKIVEQYMHTRGEARLKRH-LLFTEDGVGGLWTDSGQPIAIRGREKLGEHAVWSLQCFPDWVWTDIQI----FETQDPNWFWVECRGEGAIIFPGYPQGHYRN-------HFLHSFRFENG--LIKEQR..................... 128

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.