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Query: PF03721.14; UGDH_CAEEL/10-205; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst SKVVCVGAGYVGGPTCAMIAHKCPHITVTVVDMNTAKIAEWNSDKLPIYEPGLDEIVFAARGRNLFFSSDIPKAIAEADLIFISVNTPTKMYGRGKGMAPDLKYVESVSRTIAQYAGGPKIVVEKSTVPVKAAESIGCILREAQKNNENLKFQVLSNPEFLAEGTAMKDLANPDRVLIGGESSPEGLQAVAELVRILast
1 -95.700PF03721.14; UGDH_CAEEL/10-205; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain  ali  100  1SKVVCVGAGYVGGPTCAMIAHKCPHITVTVVDMNTAKIAEWNSDKLPIYEPGLDEIVFAARGRNLFFSSDIPKAIAEADLIFISVNTPTKMYGRGKGMAPDLKYVESVSRTIAQYAGGPKIVVEKSTVPVKAAESIGCILREAQKNNENLKFQVLSNPEFLAEGTAMKDLANPDRVLIGGESSPEGLQAVAELVRI 196
2 -18.000PF01210.23; GPDA_COXBU/7-162; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus  ali follow..  13  1.PIAILGAGSWGTALALVLARKGQKVRLWSYESDHDEMQAEGVNNRYLPNYPFPE--------TLKAYCDLKASLEGVTDILIVVPS---------------FAFHEVITRMKPLIDAKTRIAWGTKGLAKGSRLLHEVVATELG---QVPMAVISGPSLATE--------LPTAVSLASNNSQFS.......... 156
3 -15.700PF00056.23; MDH_CHLAA/3-142; lactate/malate dehydrogenase, NAD binding domain  ali follow..  15  1KKISIIGAGFVGSTTAHWLAAKE--GDIVLLDFVEGVPQG--------KALDLYEASPIEGFDVRVTGTNNYADTANSDVIVVTSGAPRKPGMSRED-KVNADITRACISQAAPLSPNAVIIMVNNPLDAMT................................................................ 124
4 -14.600PF03446.15; Q8FTI1_COREF/15-184; NAD binding domain of 6-phosphogluconate dehydrogenase  ali follow..  14  1.QIGVVGLAVMGSNLARNFARNG--HTVAVYNRSTDKTDKLIS--------------DYATDGNFIPTKTVEDFVAALEKPRRAIVMV-----------QAGAATDAVINQLADAMEEGDIIIDGGNALYTDTVCREKEMAARG-----VGAGISGGEEGALNGPS---------IMPGGP--KESWEALGPLLE. 154
5 -13.500PF02056.16; CHBF_ECOLI/6-188; Family 4 glycosyl hydrolase  ali follow..  15  1.KVVTIGGGSSYTPELLE-ELPVSELWLVDVEGGKPKLDIIFDLCQRMID-------NAGVPMKLYKTLDRREALKDADFVTTQLRV-----GQLPARELDERIPLSHGYLGQETNGAGGLFKGLRTIPV-----IFDIVKDVEELCPNAWVINFTNPAGM---EAVYRHTGFKRFIGVCNIPIGMKMFIRDVLML 183
6 -12.200PF02558.16; Q9K9R6_BACHD/6-154; Ketopantoate reductase PanE/ApbA  ali follow..  12  1..VAVIGSGSIGLLLYAYLKLANWP--ALLVTNRPEQADHLNKEGLTFVAKS-----GEHQPISVTATPLSSFSAEEAEVGFITVKSFAVKALLPQLQRKKWDGLVFFQNGMTH.................................................................................. 105
7 -11.600PF07991.12; ILVC_METAC/15-178; Acetohydroxy acid isomeroreductase, NADPH-binding domain  ali follow..  13  4KTIAIMGYGSQGHAHARNLHESGLNVVVGLRKGSSSW---------------------AKAESDGLKVMTVEEAAKAADVIMILLPDEKQASVYYSQIEPSLE------AGNALVFAHGFNIHYNQIVPPKDVDVFMVAPKG...................................................... 118
8 -11.400PF10100.9; H6NF63_9BACL/6-429; Staphylopine dehydrogenase  ali follow..  1NRVLILGTGPASVQLAVTLKNKWNC-CIGIAGRESVRFTALDESGRRVRADIQNEKHQAMQGECIVVFQGYGTITGEWDTLILAVTT---------------DAYVAVLKQIHGELLKRVRCMLLLSPTFGSNRLVRHYMNGIQSSAEIISFSTYSC-GPRPSHQVITTAVKKKVFIGSTHGRSPAIESLCGLYE. 189
9 -11.100PF03059.16; A3DUI9_MALBX/3-277; Nicotianamine synthase protein  ali follow..  13  120IKIAFVGSGPLPLTSIVLASNHLTKTSFDNYDINASANSKALGLVSSD--PDLSKRMVFHTTD----IMDVTTALKDYEIVFLAALV-----------GMDKMEKLKIIDHLAKYMAPGATLMLRSA..................................................................... 229
10 -10.400PF10727.9; Q743Y6_MYCPA/8-128; Rossmann-like domain  ali follow..  18  6.KVGIISAGRVGTALGVALERADHVV-------------------VACSAISHASRQRAQRRLPDTPVATPPEVAAGAELLLLAVPD---------------SELAGLVSGLAATVRAGTIVAHTS...................................................................... 98
11 -10.400PF01262.21; Q9S227_STRCO/141-353; Alanine dehydrogenase/PNT, C-terminal domain  ali follow..  17  29GRAVVIGGGVSGWNAAQIAIGLG--FHVTLLDKDITKLRE------------ADKIFGTKIQTVVSNAFELEKACLEADLVIGAVLIPGAKA---------------VTNELVSRMKPGSVLVDIAIDQGGCFEDSHP--------------TTHAEPTFPVHNSVFYCVANMPGAVPNTSTYALTNATLPYIVEL 184
12 -9.900PF02737.18; Q2YR99_BRUA2/5-183; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain  ali follow..  13  1.TVGIIGAGQMGSGIAHVCALAG--YNVLLHDAAPDRLEKINGNMARQVASGKLQEEQRADAMKLIRPANSMEDLAGVDLAIEAA-------------TEDETIKRKIFAQLCPVLNPEAILATNSSISITRLASTTDRPERFIGIH-------FMNPVPVMK-----------ELVRGIATEEDTFRKSNDFVT. 168
13 -9.840PF03807.17; Q21544_CAEEL/2-98; NADP oxidoreductase coenzyme F420-dependent  ali follow..  20  1.KIGFIGAGKMAQALARGLINSG----------------RITADNIIASSPKRDEVFLDQCKAGLNTTHDNAEVVQKSDVVFLAVKP---------------VHVSKVASEIAPALSKEHLVV......................................................................... 92
14 -9.420PF02254.18; Q92CZ9_LISMO/5-120; TrkA-N domain  ali follow..  13  1..FAVIGLGRFGGSICRSLVEQGME--VLAIDSDEERVNEYMSIATHAVNSTDENALRQL-------------GIRNFEHVIVAIGEDIQS......................................................................................................... 76
15 -9.390PF06690.11; D7DUD4_METV3/2-259; Protein of unknown function (DUF1188 topsan)  ali follow..  42EQAIIFGAYLSGNYIANTLKADC--GEVILIDSQPHLEDIVTGNGIKFMDLNTFMLKDKEINPDLIIDVTGLGGVDPNML-VLIIEDPKSSFDKELMEADNTHKRLCVGHKKGSLKTFRSSKISKTSGTMTLTVDVIMDSCIEIKELDGVLYSVPN........................................ 205
16 -9.350PF01408.22; YEAH_SCHPO/36-187; Oxidoreductase family, NAD-binding Rossmann fold  ali follow..  12  2.KCAIFGCGGINFGTAEGPWNLGHRLQVVALSPHKSSHERVLKQKAETEYASSYANTREFYSADEYLEYLDSHPEEKPDAYIIG--IPPETHGSTQKGA-------DLELAILKRFPDASLFIEKSAAPVEDAFAVARRLPSESVISVG............................................... 151
17 -9.270PF05175.14; A6WWW0_OCHA4/169-336; Methyltransferase small domain  ali follow..  10  30GNVADLGAGW-GYLAAQCLKFADRIKSIDLYEADYEALEAARGN---LERLGASVPIS-------FNWFDVTSEKMAGIYDTVIMNPPFHE-----GRVTDVSLGQAFIAAAASRLKPGGRLLMVANRQLPYETTLKGLFKNVTLLEEANGFKIF......................................... 168

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 2 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.