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Query: PF04497.12; Q070I7_CPRVZ/5-715; Poxviridae protein, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst PEHLRAAVLALVDCDFEFGHLCPNTLVSLRAAGIYRGFLPKSEYERVVYKYGLGSIFFFEPEDCSPVDLINFLRVNPAAAGVRPVPDYIDRWLYEILNYGCSRLLTSLLPQKVSDRALVAIVRRIVAQYRIPLASLAIRNVRLLELMDVEPLDGAAIESLFKTNEREKIDAIYRTQPIEPRLLMNFAARYGAVPNNMGMLSLSLRDISLAAKATRRFAFKFQTERYLPCDVLTHPRFLKLTEPVYQPPDFVHLNRSTAVMILRDPSLLRLHNVRRPTFTRFLVENPIVAATNPNVALSFIPKRLVSENLAVYLIKTCTEIITAFKRVTSKMLETMLSVRRFSMSAVRGKIDVDQLKIRISAIMDVYRLSIEEAIELDVLPQYTCRYYYDPNFIPQIIAAPISKELKHVLIRSFPDEKLHDSMTTSIGKMMRAIQLRSYSVPFPVYALVEPVPVKMELPETATVRGDTLYTEGYCVRVCSPFNNEAYREQALTAYVRSNNVPLRSATMPQIAEAVIFTRKLADGNVECSMGVVKNYISPGAVPPTGEAKFLFFFMDAVRLLECGIAVCCLENWYPYNHNLLVGSEKPIVASKDVCIDWGRYQFLSEIAYCDSRMATVFNTNCYYPACFAYCTYVARYLTATYVAYRNVSRSSDGANFMLTLLIGAFCNVTGLEEREAFSDMSVDRAVASGDVKHHLFIPALVNIAAYLCYRRLast
1 -196.000PF04497.12; Q070I7_CPRVZ/5-715; Poxviridae protein  ali  100  1PEHLRAAVLALVDCDFEFGHLCPNTLVSLRAAGIYRGFLPKSEYERVVYKYGLGSIFFFEPEDCSPVDLINFLRVNPAAAGVRPVPDYIDRWLYEILNYGCSRLLTSLLPQKVSDRALVAIVRRIVAQYRIPLASLAIRNVRLLELMDVEPLDGAAIESLFKTNEREKIDAIYRTQPIEPRLLMNFAARYGAVPNNMGMLSLSLRDISLAAKATRRFAFKFQTERYLPCDVLTHPRFLKLTEPVYQPPDFVHLNRSTAVMILRDPSLLRLHNVRRPTFTRFLVENPIVAATNPNVALSFIPKRLVSENLAVYLIKTCTEIITAFKRVTSKMLETMLSVRRFSMSAVRGKIDVDQLKIRISAIMDVYRLSIEEAIELDVLPQYTCRYYYDPNFIPQIIAAPISKELKHVLIRSFPDEKLHDSMTTSIGKMMRAIQLRSYSVPFPVYALVEPVPVKMELPETATVRGDTLYTEGYCVRVCSPFNNEAYREQALTAYVRSNNVPLRSATMPQIAEAVIFTRKLADGNVECSMGVVKNYISPGAVPPTGEAKFLFFFMDAVRLLECGIAVCCLENWYPYNHNLLVGSEKPIVASKDVCIDWGRYQFLSEIAYCDSRMATVFNTNCYYPACFAYCTYVARYLTATYVAYRNVSRSSDGANFMLTLLIGAFCNVTGLEEREAFSDMSVDRAVASGDVKHHLFIPALVNIAAYLCYRR 711
2 -7.140PF17663.1; A0A096NMS8_PAPAN/1-1038; Family of unknown function (DUF5525 topsan)  ali follow..  15  707................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AVAVASPAPAPVPSPAPAPAQAPASARDPAPAPVAGPAPASTSAPGDSPEQHFTGLHASLCDAISGSVA-EKLREW-----------ETAGPWGQAA---WQDCQLLTKLL---SQLQRDRTHRCPFP---------------------HVVRA--GAIFVPIHLV-LFPRLPPLQEHRV-TTLSEERALRELALPRQLIYPDLLGLQWRDCVRR 915
3 -7.020PF14543.6; I1IF70_BRADI/97-275; Xylanase inhibitor N-terminal  ali follow..  20  1..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................YYTWVDVGTPNTSFM---VALDTG-----SDLFWCGAESTTSRHLPCSHELCLL-CPYNTKYTTSSGLLVEDILDSRESHAPVKSVIIG--CGLLGL----GMADISVPSFLARAGVRN-SFSMCFTKDSGRIFF.. 154
4 -6.860PF05467.11; VU47_HHV6Z/1-677; Herpesvirus glycoprotein U47  ali follow..  17  1...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MLHISRLGLFLALF-----HSVNLIKYTSDPLEAFKTV--NW-REHFYD--------LRNLYTTFCQRNLCFT------QILTNVFSWNIRDLQCKSAVN-LSPL------NLPRAETKIVLSSTAANKSIVASSFS--LFYLLFATLSTY..... 135
5 -6.450PF15759.5; G5BQB5_HETGA/102-601; TMEM108 family  ali follow..  17  378..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EGDKPHHRATICLSKMDIA--------------W------VILAISVPISSCSTVCC---RKKTANPLSYWNNAI-----TMDYF----RHAVELPREIQSLETSEDQLSEPRSPAN---MVLVNPFCQETLFVGNDQVSEI............................... 500
6 -6.440PF15279.6; B4N5Q1_DROWI/245-568; Sine oculis-binding protein  ali follow..  27  1................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TC-DW--------------------------------CKHV-RH-AVSYVDF------QDGASQL------QFCSEKCLNQNETQAHLDMDQGLDAGNEAA-LITPDL........... 72
7 -6.300PF05695.12; YCF2_VITVI/1-1488; Plant protein of unknown function (DUF825 topsan)  ali follow..  22  7..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KSWIFELREILREIKNSHYF--LDSWTQFT---SVGSFIHIFFHQERFIKLFDPRIWSILLSRNSQGST---SNRY----FTIKGVV--LFVVAVLIYRINNRN-ERKNLYLTGLLPIPMNSIGPRNEESFGSSNINRLIVS-----LLYLP............. 143
8 -6.270PF15727.5; L5L0E7_PTEAL/12-372; Domain of unknown function (DUF4678 topsan)  ali follow..  23  249....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................YLHSMTS-------LLAGGEGSIRSLADVLV-W------SEDTL----MATGLLASSR--------SSVTDLLRSTGPRLRSASSILRNASLVISLAAGAMLFIVRMLE-------RAEQRTIEG-IRS-----AVRYLTSHLTPR. 361
9 -6.220PF01569.21; A7EIU4_SCLS1/134-294; PAP2 superfamily  ali follow..  16  20.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KWLIGGLRP-----TVC---GLNYIMYDRTICTGDEDEIDDSLESFPSAFAGFVFLSLYLNAKLKVWSNYHPAMWKLIVTYAPILGATL-------------IAGALTI---DEYHNCLAGAIIGTVAFSAYRM 155
10 -5.980PF01457.16; A4H6D3_LEIBR/42-570; Leishmanolysin  ali follow..  10  130.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................KVRQVQGTWKVTGMEGNVCGEFKVPEAHVTVGFSNIDFVLYVASVPSDTDVMAWSAFCQVFPDGRPAVG----------VINIPAAHIRSPYDQLMIRVTHEIAHAL--GFDLTIFEEMEPYGCATLKYLE----GASTAGSHLKGRNAKDEL------MAPAVTAGYYSALTMGILQYKADFTKAEVMPWAE----YATCDFLTKKCMEGTCKIVFYDNPMPTYFQYFTNSALGGRSSFMDYCPVIVGSSDGACNQ. 426
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.