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Query: PF05804.12; KIFA3_HUMAN/13-720; Kinesin-associated protein (KAP), from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst VKGGNIDVHPSEKALIVHYEVEATILGEMGDPMLGERKECQKIIRLKSLNANTDITSLARKVVEECKLIHPSKLNEVEQLLYYLQNRRDSLSGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLLNETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGLITHYKIGALCMNIIDHELKRHELWQEELSKKKKAVDEDPENQTLRKDYEKTFKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNKMVQVGLLPKLTALLGNDNYKQIAMCVLYHISMDDRFKSMFAYTDCIPQLMKMLFECSDERIDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTIPDLDWELVLKEYKLVPYLKDKLKPGAAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNNEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDESEQYLYGDDRIEPYIHEGDILERPDLLast
1 -141.000PF05804.12; KIFA3_HUMAN/13-720; Kinesin-associated protein (KAP)  ali  100  1VKGGNIDVHPSEKALIVHYEVEATILGEMGDPMLGERKECQKIIRLKSLNANTDITSLARKVVEECKLIHPSKLNEVEQLLYYLQNRRDSLSGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDIPDKVRGSALILQLARNPDNLEELLLNETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGLITHYKIGALCMNIIDHELKRHELWQEELSKKKKAVDEDPENQTLRKDYEKTFKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMVEMDIVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNKMVQVGLLPKLTALLGNDNYKQIAMCVLYHISMDDRFKSMFAYTDCIPQLMKMLFECSDERIDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTIPDLDWELVLKEYKLVPYLKDKLKPGAAEDDLVLEVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNNEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQWLEMVESRQMDESEQYLYGDDRIEPYIHEGDILERPDL 708
2 -38.400PF04826.13; ARMX3_MOUSE/110-363; Armadillo-like  ali follow..  12  1..............................................................................................................................................................................................................................................SPNSDDTVLSPQELQKVLCLVEMSEKYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTVTSRLNSSVQLAGLRLLTNMTVTNEYQHIL--ANSISDFFRLFSAGNTKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKEYKEVILKLLIIFENINDKWEENEPAQNHFSEGSLFFFLKEFQVCA------------------------DKVLGIESRHDFQVRVKVG................................................................................................................................................................................................... 254
3 -35.300PF10508.9; A7SP09_NEMVE/2-505; Proteasome non-ATPase 26S subunit  ali follow..  1..............................................................................................................................................................................................................AAEKCKELVENISNASGDEIVAFLRDLSVLISSSPNIRDLASLIPSERLFNCLRTTNTDQITYCKNILKNILKFEKPDAPA--TKYHDAVIEGLNHPTEDVRELCLIELERCSGTVNGVLALMKEDLLSYIARGMADEHLKNAQIASNVFTNLAKHEAGLKVLFDSHLQSEFNALLKTKDVRMRVYDMYITVQASPKAFDVCKESGIFEKLISEL-DGRDVLVQMNCLELLTKLASSPSGLEYLDQKGVVTKLNNLLLEVETDGIIKFFGTLATAHPLETTQQYPQFLEQTYSMISCGDPTLMPIAMETIGVIAHSEDGLRAVFNNQGRNKHIMKTIFGTSSQVDLRKRALEALASIFYSEQLTPSNMAAAPLEAIFTVAKQPFEE--LRCSALCLLRSLARYQWALQDMINCPGFLEYLLDRRTEFEKSGKEHKYDLIKELVHFPPA--KQIFDRPYFLRLQEYER................................... 486
4 -30.900PF17741.1; A0A151PBS4_ALLMI/1-268; Family of unknown function (DUF5578 topsan)  ali follow..  11  2............................................................................................................................................................................................................................................................................................TSAKEQAAIGRLLAFLQEWDNAGRAARSRILDNFIEANQGKMSLFLARLTAWLRLSYNGTCLDQLLKAIGIFLSAASGHRYLIEFLEVGGVLTLLEILGLSQDKKESIKLLQLVANGRKYKELICESYGVRSIAEFMASSKSEKAQRQVQILLDSLGHGNPKYQNQV----YKGLIALLPCTSPHAQQLSLQTLRV--QAIVGKSHPSIVEAVLGVLRSMELEVQYEAIQLIKDLTSYDV-------RPALLRGLVALLK.................................................................................................................................................................... 267
5 -23.100PF03224.14; VATH_ORYSJ/2-323; V-ATPase subunit H  ali follow..  12  57...........................................................................................................................................................................................................................................................VRVFLNILRNSKEDTVEYVLALIDEMLAVNPKRAALFGEDIYDPFLRLLLKGNWFVQEKSCKILTQIISARPKMQNGIVRGLVDWLCSQLRNPTHPSVPTAMHCLATLLREQYVRALFVQADGVKLLIPLIQSIQLLYETCLCIWLLSFYDAAVDYLSTTRVMPRLVEVVKGSTKEKVVRVVIMSIRNLLAKGAFAAQMIDLGLPHIVQNLKAQATDEDLLDALNQLEI.................................................................................................................................................................................................................................... 320
6 -20.400PF17822.1; G3S7I6_GORGO/1-229; Family of unknown function (DUF5584 topsan)  ali follow..  15............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MYGYFAGLCRRLQKFWRVTVKGFFVKKKEKKIPSAETYFHEEKIVVLGQVLMNESLPIEKRAQAAQKIGLLAFTGGPPAGNFAAEYMEEVAHLLQDEELAPKIKILLLQSVACWCYLNPVSQKRAKSLQFIPILISFFEGRFESLKFWTCYVLSVMTCNNLSCVKELKDHSALKYHLQMLA................................... 206
7 -16.600PF01602.20; Q22601_CAEEL/28-590; Adaptin N terminal region  ali follow..  1........................................................................ELKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGND--IDFGHMEAVNLLSSNKYTEKQIGYLFISVLIEQQSDLMKLIVQ--------GIRNDLTSRNPVHVNLALQCISNMGSREMVEAFCTD------LPKLLVSGETIDFVKQSAALCILKLFRNSPD---SFQPGDYASRIVHLLNDSHMGVVTSAASLIEALSKKWPEEYKGAVPLAISRLSRIVTATAPWLCVKLLRLLQNYPPPDDPSNKARLLECLEGILNKASNAKNAVLFEAIALIIHMDSEPQLLVR-----ACNQLGTFLSHRNLRYLALESMCLLATSEFSHDAVKKHQDT--IINSLKTERDVSVRQRAVDLLYAMCDRSNANQIVAE------MLAYLETADYSIREEMVLKVAILAEKYATDYT--YVDVILKLIRIAGDYVSEEVWYRVIQIVVNREDVQG------AAKTVFEALQRPACHENMVKVGGYILGEFGNFIAGDERSTAKIQFELLHSKFHL--CSITTRCLLLTTYIKFCNLFPEIKPLVQQ---VFQTDHNLRNPDAELQQRSIEYLQMTKLAS........................................................ 563
8 -15.500PF13646.6; C3YB05_BRAFL/324-412; HEAT repeats  ali follow..  21  1....................................................................................................................................................................................................................................................................................................VSSLKKLLVDEDPNIRAVASIALGKTGTCTP--------DIVEALVNLLKDEDRLVRESTCVSLGYLQ----------AQDAVPHVINAWRNDPISHVREAAQAAL...................................................................................................................................................................................................................................................................................................................... 88
9 -13.500PF11698.8; K5XHD3_AGABU/314-430; V-ATPase subunit H  ali follow..  16  40..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EHEQLKKLINLLRS-SDDPNILAIAANDVGQYVKHYERGKKFVTDMGGKDRVMELMAHTNPEVRYRALLSVQQLVSQS........................................................ 116
10 -13.100PF04063.14; K9FP34_PEND2/93-278; Domain of unknown function (DUF383 topsan)  ali follow..  14  2..................................................................................................................................................................................................................................................................LTNPKEPNADEVAMLLANLAKSEKLHNLFSLKRAIDQLMDCFNLNKYANYDYLSYLFADLSQTEKGRAYFTQRQPITKLTVFTEHKSDIRRKGVASTIKNVAFEIESHPMLFDEDGANLLPYLL...................................................................................................................................................................................................................................................................................................................................... 148
11 -12.900PF05536.11; NCDN_CHICK/4-610; Neurochondrin  ali follow..  2.....................................................................................................................PGAATLKKCLEVLRRNDSEQLAALLLVTKAVRAGDLDSKTRRQ---FTFPNRLLSSRQAPPRALGLTLLACFCTEPELAGHSQVL--NKIPTFADVLLSPCQPDCTSMVDDAYQCLAAVLATPRGPREMVTKGAASALCQAYVNGGERALALLLGLLAVSEAKCWQRDAPHLLAVLSKLSEEFVRAEDGSQFELCELLPRFIPLSPPLAEVSQRQLYKGLASILGSKLSQSQRDPALKLAASLTQACGSEWIPAGSTGSKFLALLVNLACVEVRLTLPEPLEVEGKKEVVTACYVLIEMGIQECLKEEESLLDEAQRMQLMRIMEE-----------AFGAVVFYLRQLQDPFVFASVRILGAWMAEETSSLKQEICELLPFLVRYARKLFKEGGPAENLPQTAGLVSSDSSILGQDALRFLL------------------GFCHLTAEDRPRDILISEGAPALLCDYFGSLTSTEMSLQTLCGIFLNLVVTAPN---LIRQEKTFSSLMDTLLKSLPFLLPQKDHLV............................................................... 534
12 -12.500PF08045.11; E9DYC2_METAQ/1-287; Cell division control protein 14, SIN component  ali follow..  1..................................................................................................................................................................................................................................................................................................................................................................................................MEALLSLAFDNLSSYDGPKVRKGLRQVEGLLAQICLSDGRAAAQRRQSCVDAPLSPPRKDLGELSQDPAFREFFKLQEGFEWNVAMRLIRTLD---------------RLMAKGSDGQNDLLILSALDLIQGVLLLHPPSKTLFSREQNMNLLLDLLEPFNCPAIQSATLLTLVVALIDTPSNTRTFEGLDGLLTVTSLFKSRSTSREVKLKLVEFLYCYLMPETPSIPRADQRDSVPAMLQRSPSKLAGAFNAESRRKRAGSSGLVTLTTEEKQELLSRHLSSVEDLVKDLKN............................ 283
13 -12.500PF14933.6; B7PQ18_IXOSC/10-157; CEP19-like protein  ali follow..  18  1.KKIGIRFKG--PALIVVYETP-------------SGKLHQRTMPIRDMSKNSNVRNVAESLRDR-AIFGSASLVQVEKMLRLAQESMKGKSLDECLEIVAKEFTLNPEEDLNKVDDDTLQRKKDLMNLTFEKNCKKPGDPDFKYDVEEDFDLEGAIETSG................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 146
14 -12.400PF11701.8; F6ZSU7_XENTR/243-434; Myosin-binding striated muscle assembly central  ali follow..  13  27..............................................................................................................................................................................................................................................IDTGLKKILEVGGSLVEFPGSLSVTESTRMSASVLLNKLFDDCDAERENFHKLCEDYVRSLFEGHGMDGKLRSIQTVSCLGPSEAGNRTLELTGIMESIISLCASEREIDQQVAVEALIYAAGKAKRASFITANGVLKDIYKKNENDAIRIRALVGLCKL...................................................................................................................................................................................................................................................................................................................... 192
15 -11.500PF04931.13; K2SXE2_MACPH/89-879; DNA polymerase phi  ali follow..  1.....................................KAIVRLIR--GLNSGRKAARFGTETLRQLYGSSSKEIPNIHGLVKLVAELTTPEGKASGQEKRKAIIQSSILVQPNAPEECWANVLEQLFKLAREKPWLREECGMILCEAV---KAIAQEKGQQRLVKQIVDGLCSDGLAKTPEGVSVWITVQRLPQGVWHKEDPLSTKDRQTLANVMKENFTKTSDGANETGKKVKGSSQTTALSFSWDVV--ISAFFQRHGDDPSRFANFWADIVDNFSASSSPEQKSKGLQLFTRMLGNAPKWALPFSPNLMRCLINQRNDSERFLHNAAKAPLDEMRTRSKKEPET----AAPFLENLITKHGS-DQITKNKTVEGVLGHANDVALEQIVPLFKRLIYRPEEQDSKAAEA-VADMVVSAVRSIGNDSWLREVLVGLTELAYFTPTASSSPDDLPLPAVSEASRNMFQGRLTSCLAHLLSSKLDTEMDYPYIVVSAIRSKSKSSKSLSLVF--------QADKGISKAVKQAHKQVEEITEKLLKAKDKKKPALRAFKLL-----------------FSLTIVQVYNGDPDAVSILEELAVCYESAFQKGADKSAF-----LTEVLLSFAAKPSVLFRKLSEQVFTVFA-------SELTAEGLH----SMIDILSKKESMSGQQDLFDQQGSEDGEDASEDDEDEQ. 660
16 -11.500PF14631.6; U3I414_ANAPL/1-1417; Fanconi anaemia protein FancD2 nuclease  ali follow..  1...................................................................MVSKRKLSKTDA-----SGENSKPDLPSRCSETKKPRASDKEKASAQGGLESEGVFEELLRILKAGEGQNEIAVDQMAFQKKLRLTLEKHPTYPGVVKQFISGLESHIRDRNQFKNCLLPCAPVRTEGSRTLVHSYCESLIKMLLGINILQPAVITLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKKLMQMLSVSPVPIQHDIITSLPEILEDSQQSEVARE------LGCLLKE-GRRLTVPILDALSRLDLDAELLAEV-----QQSAMTIVPSVKLEDLPVVVKFILHNVKAANAVEVISDLRKNLDLSSCVLPLQIVGSQKKLKSQVQTSSSTSQVTTSQNCVKLLFDVIKLA-QKDVSEAWIKAIENTTSVSDHKKVL-----VLLLIHSTNTKNRKQAEKVLRSKIRLGCMPEQLMQNSILVLAQTFLHAAHPAIVSFGSCMYKQA-----AVFDSYCQQEVVSALVTHVCSGNEAE--LDIALDVLTDLVVVHT-SLLMRYATFVKTILDSTQK---NPCQIRKLFYILSTLAFSQRQEGSYIQDD-MHMVIRKWLSSTVPNHKQMAVTMIGSVALKRNEGDGGSSERP-DGQLSTLLDLVGFCCEQT.......................... 628
17 -11.400PF12031.8; C3ZM58_BRAFL/582-837; SWI/SNF-like complex subunit BAF250/Osa  ali follow..  14  1................................................................................................................................................................................QLARRCICISNIFRSLSFIPGNDLEMSKHGLLLALGKLLLLHHNHPERSQAV-----RTYEKDESEIDAVPYKREEWWWDCLE-----LLRENVLVILANIAGNMDLSIY--PESISLPILDGLEKSQLSPQRLALEALAKLSILDNNVDLIQATKLNGHLVRWLGKKQAVMREFSVVLLSNLAQTITCRAIACQAGSVSALIGFLEDAEATASAIAQNPRMMQMSHNQEIGTSPDMM...................................................................................................................................................................................................................................................................................................... 256
18 -11.300PF11841.8; W4Z9X2_STRPU/133-288; Domain of unknown function (DUF3361 topsan)  ali follow..  1............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TFAQDFISNHGIELLVKMVEEGSQNGEPLSLTLKSFIELMDHNVISWDSLSANYVKKIASFVNRSSGDFQVTERALNILESSILNSTKLYNVIANEITFHNMTQLENVQNPGIQQNCLALMNALCLKAPEDEEALSARNIRVVIMEKI.................................... 155
19 -11.100PF07539.12; E5AF73_LEPMJ/886-1482; Down-regulated in metastasis  ali follow..  10  31...........................................................................................................................QALLALLNGDVDIQKAALKALLTVIAHQEQLLNLLDDARFRDELPLF-KLHDDEVAHILPIVLRLLYGKIISGKRGLESKRKAVFHQFLDIAFGPLSRISLIQNSSLDEELLQKSAVETRKQAGMLNLLDDLLGTLENTFAPFTSAVVDPVLYCAIKSSRSLTAVGTIEKNGDCTMQTSLLKAVRQRALHILAKLFTNSPDFDQAIINELVEPRLEQLPIETAQSVSGILRLFAAWSKSPHTALFLVEYNVLIKAIDCLDVPSAKDVVRCFV------------------LEEIIRNIVFLVTNQGATTTTESKLLQNRVQTEIIQQYSNVMLSRVGNLLRRSPSKDVVQTVADMAPTGSVEARSMIEIATFLLRQPAKRVNSRTKLGLLKILHEFIKRCDQQNLHELFSTIYDAICPMFAF--HERTARNLLCDIVQDLAGTQEDLVSIAK------LCYALNSDEPDFQCRSLAFDEINEHNYRLYSMKQWR----AYNMLFFIKDNDELSIRVNASLSLRRLIE.......................................................... 570
20 -10.900PF14664.6; R9ABX2_WALI9/151-516; Rapamycin-insensitive companion of mTOR, N-term  ali follow..  10  1...............................................................................................................................................................................................................................................................................GLTDALKRSFRLKYELDQSVLINGVKELSDSAGGLVRTVAYRLLRHSLVDYSSAQLYNSYGINIYLIRSLARDSSD-KEQAVFFIRALVDLGNPHGLFIDQSIVRAIISIAENGDDSLRYFCLELLAEIAILDMELLSKSQGLNILLSALTGSSLAHFAPVVASIFCYTLDHPSTRKYIKPGTDLEVSMTAFTD---------VPSAHFKASNARIERLKCANSILVVLLKN------------LLYFCVNDRN---------TVRTLIDALRVPSQEREALLDLMFELLIIKTPDWYVASLEGRRQTMYNRSTGQRKAPERSAQDSDKPEKITIIDH-ALLLVVLIDGGLIEGLTAIVEEKNQVLTRKATLLLGELL........................................................... 358
21 -10.900PF05918.11; D7TJH2_VITVI/11-547; Apoptosis inhibitory protein 5 (API5)  ali follow..  1....................................................................................................................................................................................................................................IEKLYEYGERLNEAKDKSQNVEDYRGIIA-AAKGSIKAKQLAAQLIPRFFKFFPD----LSDAAVDSHLDLCEEEELGVRVQAIRGLPLFCKDTPE------SKIVDILAQLLTAEENVERDAVHKALLSLLRQDVKASLTGLFKHIMTVDDPSTDENLREKVLNFIRDKVFPLKAELLKPQEQMERHITNLIKKDVTGAEFKMFMDFLRSLTLFGEKAPPERVQELIEIIEGQADLDAQSCLYMALPFFVRGASNSKFL--NYLNKHIIPVFDKLPEERKLDLLKNLAESSPYSAPQDSRQILPSVVQLLKKYMPRRKTGEETNFTYVECL.................................................................................................................................................... 337
22 -10.700PF16782.5; J8Q2G5_SACAR/122-421; Nucleotide exchange factor SIL1  ali follow..  1................................................................................................................................................................................................................................................DDYEFSNDFKEIRSIFDSHSTLSSH-LEDKFDNVMEFAHDYKHGYKIIVHEFPLANVSLNENLSLTLRELSTRVITSMRNNPPVVEFIDEAGFKGQVILALSKFSNILIKRYLSILNELPVTSQDLPIYSTINLQNVYQRNGKDKQLQIKVLELISKILKTGVRKN.............................................................................................................................................................................................................................................................................................................. 180
23 -10.600PF06685.11; Q8YLB6_NOSS1/1-246; Protein of unknown function (DUF1186 topsan)  ali follow..  3.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................VEEILAQLEINTKTFPRLALEAAIEQREAITPILISTLDKLSEQLLEKEDYILHIHALYLLAQF-----------REESAYPTIIKFFSVPGDVALVTEDLGRILACVS-----------GGRIEPIKQLIENSKANEYVRGAALEALLVLIAQEVITREQVIQ--YYAKLFSTLDKEDHYIQTTLVTNSAQLCAVE........................................................ 184
24 -10.300PF11894.8; C5DMA7_LACTC/4-1647; Nuclear pore complex scaffold, nucleoporins 186/192/205  ali follow..  497.............................................LSSLSFGPENSANVYHYVNLNANLSWNTVQLISDYIVKISELERKLLDGQQRDREEQDPTTIALKTGLNEE--VIILLSSLYTLIG--------------CVAHDLNEGAKAQLSSLFTDILFEFVK-----DTPLVGAALKVLSNLVPYDE--------LERSKFWFNLDSWIFKGFRLTISDDSYREAFESILTHFQDIT---GFLQLLNSLLKVRTKSTNGYL-EFGLLQFPPKLGHGYRKLGIWPYFDYVFHG-----------LAQSNKLPNPAERAAIHKPILEILSSALSSFDYSVILNSIPSGSNLLVVTDNFLTYAMESSTTAVLNYLFEENVFKNLLQNASF-KMGSITEEDCQSLALPCLALSTINQTIQETYVEELCPIVKKSASKNYFIPKDFGLHGLRSFYDAISFDLPLIV-------------------------IGLYVGHTNYKIASNSLDILDKISTEMKGRDSQAIVKD----LLSVFDSVDESARIKQAFINQLQTSITNYESFSIKMR------ILDFISKNLSYTDKQPTVAHFLLGLQIGNTISLGP-SGCSVLTSIIYLLQSLPAKLASSSMEILLKLCKNSATSKIVLRHMSESDFFETILARD................................. 1076
25 -10.200PF09759.9; Q5BC22_EMENI/804-903; Spinocerebellar ataxia type 10 protein domain  ali follow..  10  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LKKLVVLVLSSLVKCPEVQDQIRRYGGVETILSCTNFDAHNPYIKEHAVMCLKFLLEGNRENQKLIEELEAREVR.................................................................................. 76
26 -10.200PF12755.7; C4QYN7_KOMPG/59-156; Vacuolar 14 Fab1-binding region  ali follow..  14  1........................................................................................................................................................................................................................................................................NSRNGGLIGLAATAIALGQHEV---EKIIHPVLACFGDQDARVRYYACESLYNISKVAKGEILLYFNEIFDNLCKLTADSEVSVKKGAD-LLDRLIKD.......................................................................................................................................................................................................................................................................................................................................................... 98
27 -10.100PF06025.12; G3Y9G4_ASPNA/551-996; Domain of Unknown Function (DUF913 topsan)  ali follow..  1................................................................................................SRIMEFLDTFVHAVRDALGTLTSAKGFDAISDLIDHETKALRWMFRFVNHIMQHNGGLRNLIDSPQLLTSLRLVLENARVFGSHVWSNAVNILSSFIHNEPTSAVIAEAGLSKSFLEAVTSSELKAQEKIVAEPESADVEGEPSRLPETTATETTAEDGQGPREYPAAEALSCIPSAFGAICLNASGLELFKSSDALESFFEIFENPEPNLVRSLGTTFDELVRHHPALKAHIMTAVIVMVARVGLLCRAKAWSVGMGAKLWTENPEGKPIISGSTSHLLKAIGIESDDQPENASTYGVPQLTSDQLPNGGKLLLGDLSQILPSSIDNIEPKETDAVVRFLGAFFENQPNCSYFIESGGVEFVLDLA..................................................................................................................................................................................................................................................... 438
28 -10.000PF13001.7; M7TV10_BOTF1/13-513; Proteasome stabiliser  ali follow..  10  1....................................................................................................................................................................................................................................VGKVEMRIALAKDDKLEAILKPYLPPLLLKLASEHQSVRNKVISTCQHVKIRLAGNKDIV----VAALLKQYKEHPESSMLRHFDLMF-IQQSVGKLSSKDQMDLIPTLIHGLAQDAEKPTCATIFNLFGLDEHQEDSKFIASWFGKLVLLSINEGLNLTQTKITVLNFLA-----SGAFTDEERFLPAL-FASADTNSRISSIGDDLVKRSSVSLEDAEI------VRNLLGIYFALKPALKTRVLVLLT--KSAISTTFPTDIVKIVQDGVGLETIKFRNALFNYMNWVSRMGSIHDLSQVAPQLVGFLRTYIERSSDAASLRALAYETLGSLAKTTPSIVVEEELSLIRWLFRSLTEEGSSDDIFVSIEGALASLLSAFKAPLSSNLRDELRLLLLKYMTLKEEGARFATVRWANRCLEYSDIVARWI................................................. 497
29 -10.000PF12460.8; H6C711_EXODN/528-954; RNAPII transcription regulator C-terminal  ali follow..  4...........................................................................................................................................................................................................................................................LARLPDSEDEAVPDDYNPVLEGLAEISVERGLQETLMRR-LLNKVDLLCKSDNRTSFPYTCSVLGTIFYVLNRATTAANSSLDAYYDRVVIGTNEAVLDLVGRIMNLIIRHSAPDK---VQLAAENIYLLFRDSTEDKQSVDLLSLLEPPTVTILSTWLLAAIPRNTQSFV--NKTQIPQTITQLILFASKSTSRGITQSCLLQIALYVNKHVETAD-----------------LDFVDNLLSNTLSNLQDMDGSPPRDFNIRAAFTLI------KALILRLSYLTSLVGLLDEGHYPAEVCRKAAMGFATILSSDDQIRLLAPQRVFQMLTPLISEASQSPTEKENYLIALSGILASVPSNIVMPELPTLLPLLLQSLDVTDQMVKTATLETLAVVISNNPAALEE--SGHIPALVKRLIAV.................................. 427
30 -9.760PF12717.7; G8Y240_PICSO/105-271; non-SMC mitotic condensation complex subunit 1  ali follow..  12  2.........................................................................................................................................................................................................................................................................IRALAIRTMGCVRVARMVDF------IEIPLKRTLSDDNPYVRKTAAICVAKL--FDLSPKACVEFGFLDQLRGLIKDSNPMVVANALNSLFEIKDMNVDSSL-FDSELIKTLLMCLNECTGRITILDTLTKYEASSSEEA----SHIIDRATPQLQHANPSVVLSSIKVIL............................................................................................................................................................................................................................................................................... 166
31 -9.630PF14961.6; W5NL29_LEPOC/12-1308; Broad-minded protein  ali follow..  10  53...........ENMLVIEAETECCASGEGQGVGPGQDTLVHAVTR--RTRESNEYKEMILSLKNTMMVAVESLINTFEEDKLRKEETHGKSQHEQLSSHYTDNCSDSDCSFNQSYAFIKQEQLQAIAEKISQPKEVRWEALQTLCCAPPSD-----VLSCESWTGLRRNLSAALGDPDPAFSDKVLKFYAKTFSSSPLNIT-------EIYTSLAKHLESVFLSQKTSFSTAAGLDISNQDVARLLKKMRLLNEFQKEVTSF-EEIIESTLSLLS--LKTTSADKVLEPIYFLSMLLRLLENKYKSLIVASLQLLGRLLMYTHGRKLF--TDLIVILIRIMVVDSLSPACLVMDVLRTLCDRKECAVECLYAILLSPIIALLKGKQVNLHIADILARIATTERGLSLFLYDGAAHVIVQFTKAGPLTSLKGAFIFVCRQMYNTCEGLQVLKPYGLHDCIAEAWKQTVSLSERVPTPVPGDCSSSATQ--------------SQNNMVWEETLLDNLLNFAATPKGLLLLQQTGAINECVTYMFSRFTKKLQVSRGYGVMVTQVAATAPGVAAIWSSGFVQAIVSVLECGRDEVNLLSSYSAVYELLVKQELPNKPEYPLREMPTSIIDLI---DRLIIINSEAKIHSLFNFEQSHTFGLRILNVVCCNLDSLLLLESQYRISEILLQSQKDNVSESSGSEGIIDGLSI 903
32 -9.090PF07814.13; G0S7G0_CHATD/387-738; Wings apart-like protein regulation of heterochromatin  ali follow..  10  1.............................................................................................................................................................................................................................................................................AVRSLHELRQAGANSRFADE---MDDILDRVGAKSSLLRRGALLEVAQKIKNKDFRQQFRNHSDSGNLFKSLGDETDVVSGYAILAIVTTLLAATTSAHLVSQGLATLVSRLLGQTT--------ITQIAKDRKQNVSKNGQMTLTTIKYSLLELSRLSPRTLALKCLDVLMQTFAAEDELLNGEVTEHLFSIVSDSINDSSLYVLEGHSINAMQSPLSSVTWTREYAPIVASQELADLENLALRISLNITNHNEEASRLFAERGLLRRLAESACSAFGIVVNTLRDKNEEKELAAVTKVLESLI---MLGAMINFC.......................................................................................................................... 351
33 -9.000PF12231.8; Q5BCS0_EMENI/131-504; Rap1-interacting factor 1 N terminal  ali follow..  1................................................................................................................................LAGESTSSRIDAYMQFFGALRAYEKLPTEEEILHKMSLIAEFIQRDGPLDTNLVIQALKLSVVLVWHPQISPQLPDEFKLFLIEHSVVC---ESENLPKSVVTHYLTVLSTQKFPARIITAARTTRILGMLHSKGNSVISQRLMIYERLFDVAKPTFLALSTLWMDHLISGLLHQIKNVRLNALELGFNVYMASGSNSTLSKT--LRDIFDRPLANNRKLVSEVSERMSRMMSNPETGEHVPQI---GVITLLLRSKRFNIDQWQHFKEWV----------------LVLQKCFNCNDPEIKSKAIGNWNRFV........................................................................................................................................................................................................................................................................... 304

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Nika K, Tautz L, Saito K, Cerignoli F, Friedberg I, Godzik A, Mustelin T. Identification and characterization of DUSP27, a novel dual-specific protein phosphatase. FEBS Lett. 2007 May 29;581(13):2527-33. Epub 2007 Apr 30.