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Query: PF07476.11; A8AJ73_CITK8/162-410; Methylaspartate ammonia-lyase C-terminus, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst CVPEAIPLFGQSGDDRYIAVDKMILKGVDVLPHALINNVEEKLGFQGEKLREYVRWLSDRILSLRTSPRYHPTLHIDVYGTIGLIFDMDPVRCAEYIASLEKEAQGLPLYIEGPVDAGNKPDQIRLLTAITKELTRLGSGVKIVADEWCNTYQDIVDFTDAGSCHMVQIKTPDLGGIHNIVDAVLYCNKHGMEAYQGGTCNETEISARTCVHVALAARPMRMLVKPGMGFDEGLNIVFNEMNRTIALLQLast
1 -100.000PF07476.11; A8AJ73_CITK8/162-410; Methylaspartate ammonia-lyase C-terminus  ali  100  1CVPEAIPLFGQSGDDRYIAVDKMILKGVDVLPHALINNVEEKLGFQGEKLREYVRWLSDRILSLRTSPRYHPTLHIDVYGTIGLIFDMDPVRCAEYIASLEKEAQGLPLYIEGPVDAGNKPDQIRLLTAITKELTRLGSGVKIVADEWCNTYQDIVDFTDAGSCHMVQIKTPDLGGIHNIVDAVLYCNKHGMEAYQGGTCNETEISARTCVHVALAARPMRMLVKPGMGFDEGLNIVFNEMNRTIALLQ 249
2 -50.100PF13378.6; B5I604_9ACTN/167-381; Enolase C-terminal domain-like  ali follow..  10  2......................IVEQARLMQQRYGFRSFKLKGGVFP------PDEEIAAIKALAEAFP-GQPLRLDPNV------AWTVETSKYVARRLDG----VLEYLEDPT--RCIEGMAAV---------AKDAPMPLGTNMCVIAWEHLRPAVEQNAIQVLLTDHHYWGGLRRTRELAAVCEAFGLALSM-HSNSHLGISLAAMTHVAAAIPNLDHSCDTHYPWNHADDVIRPG......... 190
3 -19.300PF00113.22; ENO1_MAIZE/148-443; Enolase, C-terminal TIM barrel domain  ali follow..  13  5....PVPAFNVINGKEAMKMGVEVYHNLKSIIKKKYGQDATNVGDEGQENKEGLELLKAAIEKAGYTGKVVIGMDVAASEFFGEKDK-SGDSLKDLYKSF--VSEYPIESIEDPFDQDDWSTYAKLTDEIGQKVQ-------IVGDDLVTNPTRVAKAINEKTCNALLLKVNQIGSVTESIEAVRMSKRAGWGVMASHRSGETEDTFIADLSVGLST................................ 254
4 -8.330PF05690.14; THIG_XANCP/11-258; Thiazole biosynthesis protein ThiG  ali follow..  12  111.........................................................VQTLKAAEQLVADGFEVMVYTS------------DDPILAKRLEEIGCVAVMPLAAPIGSGLGIQNKYNLLEII-----ENAKVPIIVDAGVGTASDAAIAMELGC--LMNTAIAGARDPILMASAMRKAIEAGREAFLAGRIPRKRYASASS....................................... 247
5 -7.810PF00150.18; MANB_CALSA/46-292; Cellulase (glycosyl hydrolase family 5)  ali follow..  12  24.........................TALRGIRSWGMNSVRVVLSNGYRWTKIPASEVANIISLSRSL----KAIILEVHDTTGYGEDGAACSLAQAVEYWKEIKSVLINIGNEPYGNNNYQNWVNDTKNAIKALRDAGFKHTIMVDAPNWGRDNAQSIMEADPLRNLVFSIHMYGVYNTASKVIKSFVDKGLPLVIG.................................................... 211
6 -7.810PF01207.17; DUSB_ECOLI/13-321; Dihydrouridine synthase (Dus)  ali follow..  13  50..DEPGIRTVQIAGSD----PKEMADAARINVESGAQIIDINMG-AGSALLQYPDVVKSILTEVVNAVDVPVTLKI--------RTGWAPEHCEEIAQLAEDCGIQALT-IHGRTRACLFNGEAE-YDSIRA--VKQKVSIPVIANGDITDPLKARAVLDYTGADALMIGRAAQGR......................................................................... 218
7 -7.680PF00977.21; G8AG50_AZOBR/3-230; Histidine biosynthesis protein  ali follow..  8  43...EWLHLVDLNGAFEGKPVNGKAVESILGAVAGGIRDLKLEKGVSRVILGTVALREPELVREACREFPGKVAVGIDAREGYVAVAGWAETSTIKALDLALKFEDSGVAAI---YTDINRDGAMGGVNVEATSDLAFHLTTPVIASGGVSSIDDLIALKKEEDTGIEGVICGRA........................................................................... 222
8 -7.590PF03437.15; Y419_ARCFU/1-246; BtpA family  ali follow..  7  9.....VHLLPLPGSPEHTDLSAVIVKDARAIEEGGADALILENYGDKPFLKEVGKETVAAMTVIACEVKRDVSIGLGINVLRNDAVAALAIAKAVNADFVRVNQLFFTSVSPEGILEGKAGEVMRYKKLVDCRAMI--ADIAVKHAVHFASLEDYCLNAERSLADAVILTGKTTGGEVSLEELKYAKKTLKMPVLAGSGVNAENAARILKW...................................... 216
9 -6.860PF03320.13; I3TLZ2_TISMK/8-316; Bacterial fructose-1,6-bisphosphatase, glpX-encoded  ali follow..  13  11TEFAALACAKMIGKGDEKAADQAAVDAMRRALNSLEIDGTVVIGEGERDEAPML-------EKVGTGKGPKVDIALDLEGTTICATGGPNALAVLAMAEEGKFLNAPDVYMDKIAVGGGLPEVEENLKSLAKAKGVEISDLTACILNRPRHAELIAKVREAGV----RIQLIGDGDVAGV--IATARPDTGIDIYMGGGAPEGVLAAAALRAIG................................... 224
10 -6.710PF04476.13; MFNB_METAC/3-229; 4-HFC-P synthase  ali follow..  12  8........................REEAIIASLGGADIVDVKLGANFPWVIRDVKEVVNGRQPISATIGD-------------------NYKPGTASLAALGAAVAGADYIKVGLDIQTEAQALELLTKITLAVKDYDPSKKVVSDYKRISPLLLPAVAAEAGVDVVMVDTGIKDGEQELKEFTDLAHEHGLENAIAGSLKFEDLPVLERIG..................................... 199
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.