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Query: PF07857.12; O01810_CAEEL/4-351; Transmembrane family, TMEM144 of transporters, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst VIGLAACAVSSVFFGSMFVPIKSYDSRDGIFAQWMMSIAILLVGFIVFATTGFPGFYPLAMLGGASWCIGNATAIPIISRLGLAVSILVWNTSNCLVGWAGGRFGLFGMKAQVPASPFLNYLGLVFVVIGGSIFAQVRSEPLPIAKKTSRTSFDLENLNSEEKKALNTTESSDDGGLETEVLRPDKNLNSGTQRFFAFITAIVAGFFYGMTFVPVIRMIDNPQLYPFYPQDGISYVFSHYFGIFITSTIIFVIYSIFRRNQPYAPPNLFLPGMAAGCLWAVAQTSFFVANQHLSQTVTFPIISQMPGCIAAAWSIFYYREIRGKKNFILLGAAMSITITGATLVGLSKLast
1 -115.000PF07857.12; O01810_CAEEL/4-351; Transmembrane family, TMEM144 of transporters  ali  100  1VIGLAACAVSSVFFGSMFVPIKSYDSRDGIFAQWMMSIAILLVGFIVFATTGFPGFYPLAMLGGASWCIGNATAIPIISRLGLAVSILVWNTSNCLVGWAGGRFGLFGMKAQVPASPFLNYLGLVFVVIGGSIFAQVRSEPLPIAKKTSRTSFDLENLNSEEKKALNTTESSDDGGLETEVLRPDKNLNSGTQRFFAFITAIVAGFFYGMTFVPVIRMIDNPQLYPFYPQDGISYVFSHYFGIFITSTIIFVIYSIFRRNQPYAPPNLFLPGMAAGCLWAVAQTSFFVANQHLSQTVTFPIISQMPGCIAAAWSIFYYREIRGKKNFILLGAAMSITITGATLVGLSK 348
2 -62.600PF07168.11; K4BNE7_SOLLC/41-401; Ureide permease  ali follow..  10  7ITNLVAATLIAFTVGEIGTNSMKQPN------------------TQLSQVQDNWPSVLFAIAGGVVLSLGNLSTQYAWAFVGLSVTEVITASITVVIGTTLNYYLDDKINKAEILFPGVGCFLIAVCLGSAVHASNAADNKEKLEYFSNDSNNGVGTKDVTGSKPTNTNKVDMNDLENGEEKAKAGTAVFGKSTYIGLAITFFGGACLSLFSPAFNLSTNDQWHTDGVPHLSVYAAFFYFSVSSSLLAMILNFTFLYRPVL-VNDWDGRGWAFLAGLLSGFGNGLQFMGGQAAGYAAADAV--QALPLVSTFWGVLLFGEYRRSRTYTLLAGMLIMFIAAVAILMAS. 361
3 -52.500PF06800.12; Y169_LISMO/4-283; Sugar transport protein  ali follow..  15  1....VIALIPAVMWGIMPLVVSKIG-GKPRQQIIGTTFGALAFAIGVFIFTNTATIIIASFVSGAFWSLGQMNQFRAFTQVGVSKTMPLSTGMQLVGTSLFGVFAFHE---GTTSKLVLGFSALALIIIGIFLTSYQQHKDENSG----------------------------------------------QNMKKGIITLLISSVGYVGYVVITRWF----------DISGWDAILPQAIGMVVAGLLFSI------KSEEKRFTKQTWLNMIPGVMWATGNLALLFSNKLVGIATGFSL-SQMGVVISTIGGILFLGEKKTKKELILVIIGVVLVIIGGTMIGIA. 280
4 -22.200PF06379.12; RHAT_SALTY/1-344; L-rhamnose-proton symport protein (RhaT)  ali follow..  11  6TMGIFWHLIGAASAACFYAPFKQVKQWSSWLILPWTISALLLPDFWAYYGQFNLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLIHTEGRMTLLGVFVALIGVGIVTRAGQLKERKMGIKAEE----------------------------------------FNLKKGLLLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGALVNLGFCFIRLAKVQNLSIKADFSALGGLMWYLQFFFYAWGHARIPAYMSWMLHMSFYVLCGGLVGLVL-KEWKNRRPVAVLSLGCVVIIIAANIVGLGM 342
5 -12.100PF06027.12; S35F2_HUMAN/35-334; Solute carrier family 35  ali follow..  8  10ALGQMLSLCICGTAITSQYLAERYKVNTPMLQSFINYCLLFLIYTVMLAFRSGSD---KYILLGLADVEANYVIVRAYQYTTLTSVQLLDCFGIPVL--------ALSWFILHARYRVIHFIAVAVCLLGVGTMVGADILAGREDNSGSDV-------------------------------------------LIGDILVLLGASLYAISNVCEEYIVKK--------LSRQEFLGMVGLFGTIISGIQLLIVEYKDIASIHWDWKIALLFVAFALCMFCLYSFMPLVIKVTS-ATSVNLGILTADLYSLFVGLFLFGY-------GLYILSFTVIMVGFILYC... 299
6 -10.300PF08449.11; S35B4_DROME/6-325; UAA transporter family  ali follow..  8  3LLGMLFVFIGCCSNVVFLELIIQIDPGAGNLITFAQFLFIALEGLVFTSKFFTVALKDYVILVALFFGANVCNNYAFNFNIPMPL-HMIFRSGSLMANMIMGIV----------RYNLRQYSSVAMITAGIILCTLVSSGDVKDNTHHSLKVDTSYSDFFWW--------------------------------TVGIGLLTIALLVTAYMGIYQEVIYKKYGKHPSEALFFTHMLPLPGFLIMAGNIVQHFGIAWSSEPVAWKFPLMLFYLLCNVVTQYVCISAVYVLTTECA-SLTVTLVVTLRKFVSLLFSIIYFRNPFTLNH----WVGTILVFFGTILFANV. 319
7 -10.300PF00892.20; YDED_BACSU/160-296; EamA-like transporter family  ali follow..  11  3....................................................................................................................................................................................................AVVWGVLSGFAAAFYTLYAVGLLNK-----------FDSLVVVGWAMIIGGFALGFIHPPWQLDFQRLTAEAYAYILFVILF-MIAFWFFIKSLESLSPKETSLLGSLEP-LSAVVTTVVWLKAPFGSFQW----IGAICIIGITLILAL.. 137
8 -9.300PF04657.13; Q7CQI5_SALTY/6-143; Putative inner membrane exporter, YdcZ  ali follow..  19  67..........................................................WTLIPGLLGSFFVFASISGYQNVGAATTIAVLVASQLIGGLALDIARSHGVTLRAMV---GPAFGALLLVIGAWL....................................................................................................................................................................................................................... 138
9 -9.220PF05653.14; NIPA2_HUMAN/8-302; Magnesium transporter NIPA  ali follow..  12  4YIGLGLAMSSSIFIGGSFILKKK-SMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATL-----------VTPLG---------ALSVLVSAILSSYFLNERLNL------HGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPG---------------ATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYL---------------------------------ALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPDVIGTLSGFFTIIVGIFLLHAFK 293
10 -8.680PF10639.9; A7SF34_NEMVE/12-127; Putative transmembrane family 234  ali follow..  12  52....................................................................................................................................................................................................................................................................................LLNQSGSVLFYLTLGSADLSLAVPITNSLTFIMTTLTGRILGEESCKTETY----IGMLLVVGGVSLC.... 115
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Robinson-Rechavi M, Godzik A. Structural Genomics of Thermotoga maritima Proteins Shows that Contact Order Is a Major Determinant of Protein Thermostability. Structure (Camb). 2005 Jun;13(6):857-60.