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Query: PF09659.10; R7K0T6_9CLOT/71-437; CRISPR-associated protein (Cas_Csm6), from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst YEIEIVERRELTKVHEFDYFYQDFRNIIQNIYNDMNKDDTLLLNVSSGTPAMKSGLLVLQTLGEFPAKLIQVVTPERKINEHIHRDYDVQTLWELDEDNNENYENRCGEIECPSLSSIKKEEMIKKHVEVYDYQAALDVADTLSVQETVAYWDLLELASRRILLDFSGVDKLAVKSGVQCLPIRASSERKYFEYALSVGIKLKKEEYADFVRAITPLIVDLFEMILKKQCGVDVNAYCDVSERNQVRRWSRKKLAGTQVGEILEKEYKERFQYKDVYSVHLKLLIENISTDTELIQLINNVRSVEEGVRNLAAHQIISVTDETIRQRTGFTTTQIMDMIKRLFSYTGISVKKDYWDSYDQMNDLIIELast
1 -106.000PF09659.10; R7K0T6_9CLOT/71-437; CRISPR-associated protein (Cas_Csm6)  ali  100  1YEIEIVERRELTKVHEFDYFYQDFRNIIQNIYNDMNKDDTLLLNVSSGTPAMKSGLLVLQTLGEFPAKLIQVVTPERKINEHIHRDYDVQTLWELDEDNNENYENRCGEIECPSLSSIKKEEMIKKHVEVYDYQAALDVADTLSVQETVAYWDLLELASRRILLDFSGVDKLAVKSGVQCLPIRASSERKYFEYALSVGIKLKKEEYADFVRAITPLIVDLFEMILKKQCGVDVNAYCDVSERNQVRRWSRKKLAGTQVGEILEKEYKERFQYKDVYSVHLKLLIENISTDTELIQLINNVRSVEEGVRNLAAHQIISVTDETIRQRTGFTTTQIMDMIKRLFSYTGISVKKDYWDSYDQMNDLIIE 367
2 -43.400PF09670.10; A8ZV88_DESOH/34-416; CRISPR-associated protein (Cas_Cas02710)  ali follow..  9  48..........AENVNDLLHCHKKAEEAVARVIGRGHSRDSVIVDYTGGTKNMSVALSLAAITHGFSFSYVGGTRRTRGNVGTV----------------ENGAEKVFQSVNPWDFLAVEERKKIALLFNRHQFKAAGQLCADLAEKNVKKIGLMIEGFHEWDLLRHKTAVRRFEKLADAAGCGEKPCPAYILDLFANAERRFDEGKTDDAVLRLYRIVEMAGQQRLMDTNGIDTSNAAPEKLPAGLKS---------IYEEKYMDPESKTIKISMAAGYSLLKEMGD-DLGLQFYDQKDSFLKIQ-DSRNFLAHGFRSAREAAYMS--------LRDFIVSLNIF...................... 382
3 -20.400PF06956.11; Q2SQI7_HAHCH/2-182; Regulator of RNA terminal phosphate cyclase  ali follow..  14  69.EVSLRQIS-FSDPWDFEQVYSTLLDFAENYPFK-PDEERYLLHITTGTHVAQICWFLLCEANYIPAQILQTSPDRGERVAAGKYHL........................................................................................................................................................................................................................................................................................ 152
4 -9.310PF18869.1; A0A1F7Z354_9BACT/11-156; RnaseLS-like HEPN  ali follow..  10  7........................................................................................................................................................................................QDLQELLRESVLLISTFGKWSDYAFIVFPAAKAYEGFLKTLFRDLGFISDETYFGKRFR-----------------------VGKALNPALENHYREESIYDMLENYCQGKELPDALWETWKRGRNMLFHWFPNESNVISYGDAKQIIFEILETMDFAF........................ 146
5 -8.830PF09455.10; C8W3E9_DESAS/3-363; CRISPR-associated (Cas) DxTHG family  ali follow..  8  81.....................KELWEIFNTLIDKVDEQDSVVFDITHGFRSLSLSIAYLKFVKNVQIKGLYYGAEARDKEKNITPVFDLTDFCSLLD-----------IVGVNSFIQHGSAREISSLLVM-ELNSFGMLIEDISRALFTTRPFELVNKARNLKYYKEGTEQIIEEYYAFAGVEDHYNPLNLERHLAAVRWYVEHNYAPQALS----MRELVISFTMCQK-----GKAFDRGMRELTAGQLYRAKENSLSGKLWSK---------------------------------------LSDPRNDVIHA.................................................... 359
6 -8.680PF09623.10; A9WGH8_CHLAA/13-211; CRISPR-associated protein NE0113 (Cas_NE0113)  ali follow..  11  47CEISWIVPISVGTYHDITKAAVEFMQIACTQLRTYRNNHRLFVSIAGGRKVMSALLALAVQFYGAECLFHIWVPPWLEEEGEIGQLRGLQPEQINARLHNRDPKDRPQLVDLPFIALFPMLPDIREALAG-PIDKNVKSMLVSTGL............................................................................................................................................................................................................................. 199
7 -8.180PF18737.1; A0A1H8V536_9PROT/6-223; MAE_28990/MAE_18760-like HEPN  ali follow..  7  1..........................................................................................................................................FRAQLEGELTWRTQEILFFQNQCEKLDSAEEKDKFRR-------------ALILLLYSNFEGYCIFSLYISAILDCKDANYSLVAATLHDVFV-TLRGVKKAKEFKNTDPDDSRLHLFARERDFVEHSSEIFKRESNLGPVVLKKNLFKLGLPYTEFEEYEKEIDQLLKLRNKIAHG-QGISVKLYETI----RASAFKIMSGITTNLTNAIGSQMY............ 218
8 -8.130PF09651.10; A8ZV94_DESOH/49-188; CRISPR-associated protein (Cas_APE2256)  ali follow..  21  57.KVETVTLEGLSDRSVFDFRTKGLRNLVKAIAEKRHGAESVLINATGGYKAQISFAGMIGQALEIPVCYLFEKFSE................................................................................................................................................................................................................................................................................................... 133
9 -7.960PF18725.1; F8JQQ1_STREN/30-244; SAV2148-like HEPN  ali follow..  6  31..........................................................................................................................................................................................................RAGRAYVWLNLVEQRLRAVVSAVLRPIYEPVHGEEWVTAAAGPAGHEWVQRAAAVREVSRRKGYLLDPADDTLVSFLTLPQLRELVVQHWPCRRELELALDELEVARHVVSRN-RALSGTVLDQT-ERAAARLLAMLGGGPEAD-----AAARLPVDAVEEIVGD 195
10 -7.320PF09002.11; Q5E4N1_VIBF1/1-380; Domain of unknown function (DUF1887 topsan)  ali follow..  9  55.....SDFFEIPNIVDTHAIKQSLQALAAEMKLH---FSDIKLNASCGLRHRLLSAYEVFRSYHWPIFVVEPYSPDGRKQKHVADNIRLSDYLAIFGARCEFSETELPESIDKRLRELCQRWA-----NALELGPGLATLNYLATTCRKEQRLDVEVTEKQ-----QSYKELNMLLTDLVETGLATYENGILTFDCEEARRLANGEWLEILV-HNTVVDIQQYLPTLQDHSLNVQVHREIGEKDVRNELDVVSIVNNKLH-IIECKTKGMRDDGDDTLYKLESLRDLLGGLQARAMLVSFRPLRNNDIMRAQDLGLAIIGPDELGD--------LKKHLLNWFL....................... 378
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;