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Query: PF10508.9; A7SP09_NEMVE/2-505; Proteasome non-ATPase 26S subunit, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst AAEKCKELVENISNASGDEIVAFLRDLSVLISSSPNIRDLASLIPSERLFNCLRTTNTDQITYCKNILKNILKFEKPDAPATKYHDAVIEGLNHPTEDVRELCLIELERCSGTVNGVLALMDKEDLLSYIARGMADEHLKNAQIASNVFTNLAKHEAGLKVLFDSHLQSEFNALLKTKDTVRMRVYDMYITVQAHSPKAFDVCKESGIFEKLISELDGRDVLVQMNCLELLTKLASISPSGLEYLDQKGVVTKLNNLLLEVETDPLITLIIPGIIKFFGTLATAHPLETTQQYPQFLEQTYSMISCGDPTLMPIAMETIGVIAHSEDGLRAVFNNQGRNKHIMKTIFGHATSSQVDLRKRALEALASIFYSEQLTPSEELCEFAKVLYKNMAAAPLEAIFTVAKQPFEELRCSALCLLRSLARYQWALQDMINCPGFLEYLLDRRTEFEKSGKEHKYDLIKELVHFPPAKQIFDRPYFLRLQEYEREGPFFARAEAAVAFEGADLast
1 -95.600PF10508.9; A7SP09_NEMVE/2-505; Proteasome non-ATPase 26S subunit  ali  100  1AAEKCKELVENISNASGDEIVAFLRDLSVLISSSPNIRDLASLIPSERLFNCLRTTNTDQITYCKNILKNILKFEKPDAPATKYHDAVIEGLNHPTEDVRELCLIELERCSGTVNGVLALMDKEDLLSYIARGMADEHLKNAQIASNVFTNLAKHEAGLKVLFDSHLQSEFNALLKTKDTVRMRVYDMYITVQAHSPKAFDVCKESGIFEKLISELDGRDVLVQMNCLELLTKLASISPSGLEYLDQKGVVTKLNNLLLEVETDPLITLIIPGIIKFFGTLATAHPLETTQQYPQFLEQTYSMISCGDPTLMPIAMETIGVIAHSEDGLRAVFNNQGRNKHIMKTIFGHATSSQVDLRKRALEALASIFYSEQLTPSEELCEFAKVLYKNMAAAPLEAIFTVAKQPFEELRCSALCLLRSLARYQWALQDMINCPGFLEYLLDRRTEFEKSGKEHKYDLIKELVHFPPAKQIFDRPYFLRLQEYEREGPFFARAEAAVAFEGAD 504
2 -35.300PF05804.12; KIFA3_HUMAN/13-720; Kinesin-associated protein (KAP)  ali follow..  207IGALCMNIIDHELKRHELWQEELSKKKKAVDEDPENQTLRKDYEKTFKKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMKNIVHMLVKALDRDNFELLILVVSFLKKLSIFMENKNDMV-EMDIVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNKMVQVGLLPKLTALLGNDN-YKQIAMCVLYHISM-DDRFKSMFAYTDCIPQLMKMLECSDERIDLELISFCINLAA-NKRNVQLICEGNGLKMLMKRALKFKDP--------LLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIECLGTLANLTIPDLDWELVLKEYKLVPYLKDKLKP--GAAEDDLVLEVVIMIGTVSMDDSCAAL------------LAKSGIIPALIELLNAQQEDFVCQIIYVFYQMVFHQATRDVIIKETQAPAYLIDLMHDKNNEIRKVCDNTLDIIAEYDEEKKIQSEKFRWHNSQWLE.................. 673
3 -25.300PF04826.13; ARMX3_MOUSE/110-363; Armadillo-like  ali follow..  12  10SPQELQKVLCLVMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNCDDTVTSRLNSSVQLAGLRLLTNMTVTNEYQHIL---ANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNEYKEVILKLLIIFENINDNKWEENEPAQNHFSEGSLFFFLKEFQ-----VCADKVLGIESRHDFQVR..................................................................................................................................................................................................................................................................... 250
4 -21.300PF17741.1; A0A151PBS4_ALLMI/1-268; Family of unknown function (DUF5578 topsan)  ali follow..  14  6EQAAIGRLLAFLQEWDNAGRAARSRILDNFIEANQGKMGLFLARLTAWLRLSYNGTCLDQLLKAIGIFLSAASGHRYLIEFVGGVLTLLEILGLSQEEDKKESIKLLQLVANAGRKYKELICESYGVRSIAEFMSSKSEKAQRQVQILLDSLGHGNPKYQNQVYKGLIALLP---CTSPHAQQLSLQTLRVVQAIVGK-----SHPSIVEAVLGVLRSMELEVQYEAIQLIKDLTSYD-------VRPALLRGLVALLK..................................................................................................................................................................................................................................................... 267
5 -18.900PF18795.1; G0VA94_NAUCC/12-250; DNA mismatch repair protein HSM3, N terminal domain  ali follow..  12  3..PMLEELNSALEGDEIPAHINSLIDKCSLNLSSLAQYNGDATRILVNIKRILLESSMVPNNSLIELLENVIKVCSFEDVLEIYIDDLTKALQSKNSLLISAGCKIISK-----SYPKAIFAPSILLDILLTLFTNTETFVINAIENVFKSLSSDELIRRKIMFDNAPLLLRVKRDFEVTPYSRLIALLKIEFEYIQPSEFNPKLFVIDRTELFKSIETDILLFIQITMYYTRMVQ............................................................................................................................................................................................................................................................................ 237
6 -17.300PF01602.20; Q22601_CAEEL/28-590; Adaptin N terminal region  ali follow..  13  50......EAVNLLSSNKYTEKQIGYLFISVLIEQQSDLMKLI----VQGIRNDLTSRNPVHVNLALQCISNMGSREMVEAFCTDLPKLL--VSGETIDFVKQSAALCILKLFRNSPD---SFQPGDYASRIVHLLNDSHMGVVTSAASLIEALSKKWPEEYKGAVPLAISRLSRIVTATYTDLQD----------------------------YTYYFVPAPWLCVKLLRLLQNYPPPDDPSNKARLLECLEGILNKAQDAPKSKKVQHSNAKNAVLFEAIALIIHMDSEPQLLVRACNQLGTFLSHRETNLRYLALESMCLLATSEFSHDAVKKHQDTIINSLK------TERDVSVRQRAVDLLYAMCDRSNANQ------------------IVAEMLAYLETADYSIREEMVLKVAILAE-----KYATDYTWYVDVILKLIRIAGDYVSEEVWYRVIQIVVNRED---VQGYAAKTVFEALQRPACHENMVKVGGYILGE 478
7 -16.600PF12717.7; G8Y240_PICSO/105-271; non-SMC mitotic condensation complex subunit 1  ali follow..  2...........................................................IRALAIRTMGCV----RVARMVDFIEIPLKRTLSDDNPYVRKTAAICVAKLFDLSPK---ACVEFGFLDQLRGLIKDSNPMVVANALNSLFEIKDMNVDSSLFDSELIKTLLMCLNECTEWGRITILDTLTKYEASSSEEASH-----IIDRATPQLQHANPSVVLSSIKVI................................................................................................................................................................................................................................................................................. 165
8 -15.800PF17822.1; G3S7I6_GORGO/1-229; Family of unknown function (DUF5584 topsan)  ali follow..  11  10..............................................................................QIWVKMYGYFAGLCRRLQKFWRVTVKGFFVKKKEKKIPSAETYFHEEKIVVLGQVLMNESIEKRAQAAQKIGLLAFTGGPPAGNFAAEYMEEVAHLLQDEEKIKILLLQSVACWCYLNPVSQKRAKSLQFIPILISFFEGRFLLLKFWTCYVLSVMTCNNLSCVKELKDHSALKYHLQMLAAENWSGWTENFAEVLYFLIG................................................................................................................................................................................................................................. 226
9 -15.100PF13646.6; C3YB05_BRAFL/324-412; HEAT repeats  ali follow..  13  1.............................................VSSLKKLLVDEDPNIRAVASIALGKT------GTCTPDIVEALVNLLKDEDRLVRESTCVSLGYL------------AQDAVPHVINAWNDPISHVREAAQAAL................................................................................................................................................................................................................................................................................................................................................................... 88
10 -15.000PF03224.14; VATH_ORYSJ/2-323; V-ATPase subunit H  ali follow..  10  22ANKLISQLLRRYDHKPESQRGPLLDEDGPSY--------------VRVFLNILRNSKEDTVEYVLALIDEMLAVNPKRAALEDIYDPFLRLLLKGNWFVQEKSCKILTQIISARPKMQNGIVPRGLVDWLCSQLPTHPNCSVPTAMHCLATLLREQYVRALFVQADGVKLLIPLIQQSIQLLYETCLCIWLL-SFYDAAVDYLSTTRVMPRLVEVVKSTKEKVVRVVIMSIRNLLA-KGAFAAQMIDLGLPHIVQNLKAQAWTDEDLLDALNQLEIGL.................................................................................................................................................................................................................................. 322
11 -12.900PF14664.6; R9ABX2_WALI9/151-516; Rapamycin-insensitive companion of mTOR, N-term  ali follow..  11  1.........................................................................................................GLTDALKRSFRLKYELDQSVLINGVKECLDSAGGLVRTVAYRLLRHSLVDYSSAQLYNSYGINIYLIRSLASDQLEKEQAVFFIRALVDLGNPHGLFI-DQSIVRAIISIAENGDDSLRYFCLELLAEIAILDM---ELLSKSQGLNILLSALTGSSPDLFAPVVASIFCYTLDHPSTRKYIKPGTDLEVSMTAFTDV-SNARIERLKCANSILVVLLKNWSG---LLYFCVNDRNTVRTLIDALRVPSQELREALLDLMFELLIIKTPDWYVASLEGRRQTMYNRSTGQRKAPERSAQDSDKPEKITIIDHYIALLLV------VLIDGGLIEGLTAIVEEKNQVLTRKATLLLGELLR....................................... 359
12 -12.500PF05536.11; NCDN_CHICK/4-610; Neurochondrin  ali follow..  11  3GAATLKKCLEVLRDANDSEQLAALLLVTKAVRDSKTRRQIFDAIGFTFPNRLLSSRQAP---------------------------------GCPEHTFRALGLTLLACFCTEPELAGH----PTFADVLLSPCQPDCTSMVDDAYQCLAAVLATPRGPREMVTKGAASALCQAYVNGGYGSERALALLLGLLAVSEAKCWQRDAPAVLSKLSEEFVRAEDGSQFELCELLPRFIPLSPPLAEVSQGSECVRQLYKGLASILGSKLSQSQRDPALKLAASLTQACGSEWIPAGST-VRLTLEEPEPLEVVLIEMGIQECLKEEESLLDEAQRMQLMRIMEEAFGAVVFYLRQVKEEFVFASVRILGAWMAEETSSLKQEICELLPFLVRYARKLTAGLVSSDSSILGQDALRFLLPGFCHLTAEDRPRDILISEGALCDYFLPGSLTSTEMSLQTLCGIFLNLVVTAPNLIRQEKTFSSLMDTLLKSLPFLLPQKDHLVLAAN. 538
13 -12.500PF05918.11; D7TJH2_VITVI/11-547; Apoptosis inhibitory protein 5 (API5)  ali follow..  1.IEKLYEYGERLNEADKSQNVEDYRGIIAAAKGSIKAKQL-----------------------AAQLIPRFFKFFP--DLSDAAVDSHLDLCEEEELGVRVQAIRGLPLFCKDTPEYV-----SKIVDILAQLLTAEENVERDAVHKALLSLLRQDV------------------------KASLTGLFKHIMTVDDPSTDENLREKVLNFIRDKVFPLKAELLKPQEQMERHI----------------TNLIKKSLEDVTGAEFKMFM--DFLRSLTLFGEKAPPERVQELIEIIEGQADLDAQFNVSDGDHIDRLISCLYMALPFFVRGASNSKFLNYLNKHIIPVFDKLPEERKLDLLKNLAESSPYSAPQDSRQILPSV-----------VQLLKKYMPRRKTGEET---------------------NFTYVECLLYTFHHLAYKAPNATNSLCGYKIVTGQPSDRLGEDFSEYYKDFTER................. 383
14 -12.500PF11701.8; F6ZSU7_XENTR/243-434; Myosin-binding striated muscle assembly central  ali follow..  1..SALNLLMKVVPRKSFRDPDNGMTLWVIDTGLKKILEVGGSLVEFPGSLSVTESTRMSASVLLNKLFDDLKCDAERENFHKLCEDYVRSLFEGHGMDGKLRSIQTVSCLLQGPEAGNRTLELTGIMESIISLCASEREIDQQVAVEALIYAAGKAKRASFITANG-VALLKDIYNENDAIRIRALVGLCKL........................................................................................................................................................................................................................................................................................................................ 192
15 -12.100PF12755.7; C4QYN7_KOMPG/59-156; Vacuolar 14 Fab1-binding region  ali follow..  15  1..........................................................NSRNGGLIGLAATAIALGQHEVLEKIIHPVLACFGDQDARVRYYACESLYNISKVAKGEILLYFNE-IFDNLCKLTADSEVSVKKGAD-LLDRLIKD............................................................................................................................................................................................................................................................................................................................................................. 98
16 -11.800PF16782.5; J8Q2G5_SACAR/122-421; Nucleotide exchange factor SIL1  ali follow..  13  12.............................................IRSIFDSHSTLSSHDITVLEDKFDNVMEFAHDYKHGYKIIVANVSLNENLSLTLRELSTRVITSCMRNNPPVVEFIDERGFKGQVILALSKFSNILIKRYLSILNELPVTSQDLPIYSTINLQNVYQRNGK-DKQLQIKVLELISKILKTGVRKNEDPDLQEWANEFQAMAQDKDELHMRTFFDTLYNLKSIFKSDIT--INKAFLNWLAQQCKERQSN................................................................................................................................................................................................................................................ 258
17 -11.600PF06685.11; Q8YLB6_NOSS1/1-246; Protein of unknown function (DUF1186 topsan)  ali follow..  11  1...........................................MQVEEILAQLEINTKTFPRLALEAAIEQREAITPISTLDKLSENLEQLLEKEDYILHIHALYLLAQF-----------REESAYPTIIKFFSVPGDVVTEDLGRILACVSGGR-----------IEPIKQLIENSKAVRGAALEALLVLIAQEVITREQVIQ--YYAKLFSTLDKEDHYIQTTLVTNSAQLCAVE-----------LQEQINRAFEQNSVDL............................................................................................................................................................................................................................................... 200
18 -11.200PF12460.8; H6C711_EXODN/528-954; RNAPII transcription regulator C-terminal  ali follow..  12  4....LARLPDSEDEAVPDDYNPVLEGLAEISVERGLQETLMRRL-LNKVDLLCKSDNRTSFPYTCSVLGTIFYVLNRNSSLDAYYDRVVIGIAKSGPLTNEAVLDLVGRIMNLIIRHSAPDKVQLAAENIYLLFRDSTEDKQSVDL-----LSLLEPPTVTILSTWLLAAIPRNTQSFVLNKTQIPQTITQL-------------------ILFASKSTSRGITQSCLLQIALYVNKHVETADLDFVDNLLSNTLSNLQDEPMDGSPP--RDFNIRAAFTLIKALILRLSPKTDQYLTSLVGLLDEGPAEVCRKAAMGFATILSSDDAQIRLLAPQRVFQMLTPLISEKFRASSPTEKENYLIALSGILA-----------SVPSNIVMPELPTLLPLLLQSLDVTDQMVKTATLETLAVVISNNPAALEESGHPALVKRLIA............................................................. 426
19 -11.000PF12348.8; B8M2E9_TALSN/325-551; CLASP N terminal  ali follow..  55....LDGILKVVNSLRTTLSTTGCLLIQEIAKVCGPGIDNMVEILLQNMIKLCAGMKKISAQNANATVDAIISNVTYVPRI---LQHLSFACQDKNVQPRLFAAGWLKTLLNKQARHKSSIEHGGVEKCIKKCLGDPNPGVRESMRGTFWTFYKIWPDRAEEIISTLDAKSKTLLE........................................................................................................................................................................................................................................................................................................................................ 227
20 -10.700PF08045.11; E9DYC2_METAQ/1-287; Cell division control protein 14, SIN component  ali follow..  10  5.............................................LSLAFDNLSSYDGPKVRKGLRQVEGLLA------------QICLSDGRAAAQRRQSCVDGEADAPLSPPRKDLGELSQDPAFREFFKLQEGFEWNVAMRLIRTLDRLMAKGSD-----------------GQNDLLILSALDLIQGVLLLHPPSKTLFSREQNMNLLLDLLEFNCPAIQSATLLTLVVALIDTPSNTRTFEGLDGLLTVTSLFKSRSTSREVKLKLVEFLYCY.................................................................................................................................................................................................................................. 209
21 -10.700PF12530.8; D8SAX6_SELML/484-706; Protein of unknown function (DUF3730 topsan)  ali follow..  13  4......................................................................................LKYHQRHDVNTNVVIAFLNALPDICGHPTTVPLSM---HLLQHMVD--YKGNLRIQATSIRLIYKIWQHTDRAYSFLQKTLVPSWFSQAKEETDVLLSRATSLRDLCGHDPD-----VGIELILSVQACVECRSPVVKALGLQSLSFLCGH-----DAIDFYTAWKVIAKLFSPLPISPSISESFCMLLKHGALDANLNAEDAHAVLNALWEFASCD-SEEWYRTRSAAVESL......................................................................................................................................................................................... 223
22 -10.600PF05004.13; T1J854_STRMM/21-332; Interferon-related developmental regulator (IFRD)  ali follow..  11  44.IDKLKDAIDGATQKNAKGRQTCLESIQNVLSRKYLPDVIDTRRETECIKSSLKRGKVDEQSAAAILAVLTCPGSSSDSMFAELCPVLTTSLNDKSLTTRGTCATALA--------------------LLALIIGEMEQGTIISLMSTFEALFSASYFKGN-------GTVPNHALEVTALHSSALAAWSLLLTVVSINDVSSMAERHVMRLSELLESSDVELRIVAGETIALLYEIAREEDENFMGGETLDDLSFKLKQLATDS............................................................................................................................................................................................................................................... 288
23 -10.500PF11841.8; W4Z9X2_STRPU/133-288; Domain of unknown function (DUF3361 topsan)  ali follow..  12  12..............................................................................................................................IELLVKMVEEGSQEPLSLTLKSFIELMDHNVISWDSLSANYVKKIASFVNRSSGLDFQALNILESSILNSTKLYNVIANEITFHNMTQHLNVQNPGIQQNCLALMNALCLKAPEDEEALSARNIRVVIMEKI...................................................................................................................................................................................................................................................... 155
24 -10.500PF14631.6; U3I414_ANAPL/1-1417; Fanconi anaemia protein FancD2 nuclease  ali follow..  10  79....QKKLRLTLEKTYPGVVKQFISGLESHIRDRNQFKNCLLPCAPESLIKMLLGINILQPAVITLLLEKIPEFFFDVV-------------GTFGTNFPRLIVNQFKWL--------GLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQ------QSEVARELGCLLKEGRRLTVPILDALSRLDLDAELLAE------VQQSAMTIVPSVKLEDLPVVVKFILHNVKAAN-------AVEVISDLRKNLDLSSCV-LPLQIVGSQKKLKSQVQTSSSTSQVTTSQNCVKLLFDVIKLAQKDVSEAWIKAIENTTSVSDHKKVLIRLGCMPEQLMQNAFQDHSMVIRDFFPSILVLAQTFLHAAHPAIVSFGSCMYKQAFAVFDQEVVSALVTHVCSGNEAELDIALDVLTDLVVVH--TSLLMRYATFVKTILDSTQKLNPCQIRKLFYILSTLASQRQEGSYIQDDMHMVIRKWLSSTVPNHKQMGIIGA.... 582
25 -10.300PF10165.9; L2FRK2_COLGN/97-511; Guanine nucleotide exchange factor synembryn  ali follow..  1................................................................................................................................................ALEELKIYGRDPRDAGPIFTPEGIEILTKHNSPSSSTSRAALRVLANAMLLNPQTRQMFVDLGYEDKACKKLKSDSFDDEFLASRVI--TYETNIDLLGLIQKHGLAETVVEQLGKSPVDPMEDMALNEILRLLFNVSHFCSSEASAFTASIPHIIALLWKKPLDPPFNSLVNALLNLKLEDEDIQSSIYPKNGPKKVSERLIELLDNELEQLTTPLVGVLRRVHDGAPEEVKKYIRTTLRKEVLGRGTSLTSRLLRNSTNPTPQLRDAISHLLFDMSDKD--ASKFVENVGYSGFLFQNVPEMTEEEKEREAERLFVLFERLRRTGIVDIQ--NPVEQAVRSG................ 414
26 -10.200PF11698.8; K5XHD3_AGABU/314-430; V-ATPase subunit H  ali follow..  42..................................................................................EQLKKLINLLSSDDPNILAIAANDVGQYVKHYERGKKFVTDMGGKDRVMELMAHTNPEVRYRALLSVQQLVSQS............................................................................................................................................................................................................................................................................................................................................................ 116
27 -10.100PF12719.7; M3XT68_MUSPF/558-858; Nuclear condensing complex subunits, C-term domain  ali follow..  10  2...............................................................CLILCYELLKQMSGATMNGIIESLILPGIVSVHPVIRNLAVLCLGCCGLQNQDFAS-----KHFVLLLQVLQIDDVTIKISALKAIFDQLNKALQGENAEINTDGDQDIKDAKEETATAKNVLKLLSDFLDSEVSELRTGAAEGLAKLMFGLLVSSRILSRLHCLGVFFPMFAYASRTNQECFEEAFLPTLQTLASAPASSPLAEVDITNVAELLVDLTRPSGLNLQAKNSQAIKICNEILTCPCSPEIRVYTKALGSL...................................................................................................................................................................................... 299
28 -10.100PF16201.5; D7MEK1_ARALL/1978-2168; Nucleolar pre-ribosomal-associated protein 1  ali follow..  1.............................................LAVAFVSMSSADLGMRKLGYETLQIFLDALENCRKNKHLLMYVQNGVEEPWQRIPTVSAIFAAE--------------------TSLILLDPSHEHYVPINKLLQS--------SSTLKLRGIPLFHDFFWSSAVNFRSQRFWELRLVCKSDDDVQIYIKNSILETVISFSSSPDDETKRLILQVVRKSVKFHKMARHLVENCGLFS............................................................................................................................................................................................................................................................ 190
29 -9.970PF13001.7; M7TV10_BOTF1/13-513; Proteasome stabiliser  ali follow..  10  1....VGKVEMRIALAKDDKLEAILKPY------------------LPPLLLKLASEHQSVRNKVISTCQHVKIRLAGNKDIVLPVAALLKQYKEHPESLRHFDLMFIQQSVGKLSSKDQM----DLIPTLIHGLAQAEKPTCATIFNLFLRLLPQLKVPSRGSKEDTELRHQLGLDEHQEDSKFIASWFGKLVLLSIVRAAP-TKITVLNFLASGAFTDEERFLPALFASADTNSRISSIGDDLVEDAEIVRNLLGIYFALKPALKTRVLVLLTKSAIST----------TFPTDIVKIVQDGVGLETIKFRNALFNYMNWVSRMGSIHDLSQVAPQLVGFLRTYIEDERSSDAASLRALAYETLGSLAKTTPSIVVEEELSLIRWLFRSLTE----------EGSSDDIFVSIEGALASLLSAFKAPLSSNLRDELRLLLLKTLKEEGEIVRSARFATVR........................................... 481
30 -9.910PF01603.20; A0A1I7VZ75_LOALO/113-523; Protein phosphatase 2A regulatory B subunit (B56 family)  ali follow..  11  1.............................................LPNIKDAEPTAQEELFIQKLRQCSVVFDFAVDPLS------------DLKYKEVKRTTLNELTDYILSCQNVITEAIYPEVISML--------------SSNLFRVLSPPSNPTGAEFDPDEDEPTLEAAWPHLQLVYEFFLRFLESADFQPSIAKRYVDQKFVLKLIELSDSEDPRERDFLKTTLHRIYGKFLGLRAYMRKH-GIAELLEILGSIINGFALPLKEEHKTFLLRVLIPLHKVKSLSVYHPQLAYCVVQFLEKDPTLTEPVILSLLKFWPKVHSPKEVM--------FLNEFEEILDVIEPAEFQKVMVPLFQQLARCVSSPHFQVAERALYYWNN------EYIMSLISDNAVVILPIMFPALYRNSKNHWNKTIHGLIYNALKLFMEINQR----------ECSQNFNREREDESAKLKAKVSKWEMIERKA................ 411
31 -9.620PF12726.7; A7EJU8_SCLS1/90-823; SEN1 N terminal  ali follow..  11  35DDETVAELSNRLNAIDFQRIDNGLRSSKKVISDVESPMR-YDSSLLLSLYESLCCKSEDNLSKHFDFVFEEIQAKKVLRI-SDILPATGRFLFDKNVIRLRFARCAWQKATTMTHSLRAMEVQPNVYMLALNHLTCKSERIGQLVIEVLRGLLKKATIAENIFRGGGFEGMLCRINFEDPEISFALAWIPELVESLPSDRQYDACSFLLEFLLRRYQKTTLACCCVALDTLRATLNTFVDSEYNINPSTSLIFINNIMG---------LVDQYKETIARSADLNMADATHQEMRRLGMLVVRDALALDCKSLSAEFQAL------AQNIPIQQGLRSHSQPIWQAVLDIFRPGNVDLAKSILAATTHLTGLDELTPQTK-------------KSPLPPSHLQYNKDFHQLTENVSRIFERLSDFD-HLIEMYRDPQTSRPLFAALLSADQEIFEAAVEVVKAATGQVSKREAMSVPMLNSLTFATVR................. 580
32 -9.580PF04931.13; K2SXE2_MACPH/89-879; DNA polymerase phi  ali follow..  1..KAIVRLIRGLNSGRKAARFVALTETLRQLYGSSSKEIPGLEPNIHGLVKLVAESGQEKRDYLLGRVSILVQPNAPEECWANVLEQLFK-LAREKPWLREECGMILCEAVKAIAQEK----QQRLVKQIVDGLCSDGLAKTPEGVSVWITVGDDPSRFANFWADIVDNNLFSASSSPEQKSKGLQLFTRMLGNAPKWALPSIFSPNLMRCLINQRNDSERFLHNAAKAPLDEMRTRSKKEPETITKNKTVEGVLGHANDVALEQIVPLFKRLIYRPEEQDSKAAEAQRRTVADMVVSAVRSRNKENAIGNDSWLREVLVGLTELA-----YFTPTASSSPDDLPLPAVSEASRNMFQGRLTSCLAHLLSSKLDTEMDYPYIVVSAIRSKSKSSKSLSLVFQADKGISKAVKQAHKQVEEITEKL--YESAFQKGALTEVLLSFAAKPSVLFRKLSEQVFTVFASE------LTAEGLHSMIDILSKKESMSGQQDLFDQQGSE 647
33 -9.460PF01347.22; VIT_ICHUN/18-588; Lipoprotein amino terminal region  ali follow..  10  287...........................................................................................................................SEIHTVLKHLVENNQLSVHEDAPAKFLRLTAFLRNVDA----GVLQSIWHKLHQQKDYRRWILDAVPAMATSEA-----------LLFLKRTLASEQ-LTSAEATQIVYSTLSNQQATRESL------SYARELLHTSFIRNRPILRKTAVLGYVFRYCANTVSCPDELLQPLHDLLSQSSDRADEEEIVLALKALGNAGQP--------NSIKKIQRFLPGQGKSLDEYSTRVQAEAIMALRNIAKRDPRKVQEIVLPIFLN-----------------VAIKSELRIRSCIVFFESKPSVALVSMVAVR---------LRREPNLQVASFVYSQMR........................................... 571
34 -9.260PF08324.11; G0NNV7_CAEBE/596-852; PUL domain  ali follow..  11  1.......................................IGLSGKGEKAVAKLKELNEKQDAFQLNCLEELFHLATTSNYSSDVAQSAFDTALQWPVEHLAPVLDFFRVALTHESLNSYFCTGERGQDLVMKIIAPADMVLKVMVCRCIGNAFAHPAGRSLFASYELSTLAPQLLNEKQILQMSAATALANWSLALLKQSETVEQLGPKEDLLRALGFVSEEALSRLLQTIVTIMWGDSSVIRLAKNRNMAAIAARLKDATQNETTKSMA.......................................................................................................................................................................................................................................... 255
35 -9.180PF04118.14; C4QZW5_KOMPG/11-303; Dopey, N-terminal  ali follow..  12  7.LSNVQKTIASFASVVEADYISFLGRLQKALQSNPSKDTHWIPEAYKLLSQCLSNT-NGVHKKCLELYHDIFIMLGQEKLGQDWLPGLLPLMNYASITVRPQLIDLFSSFVAKIAPAYLHPVLRALLLGIWPALDDPTSECFESAFQLVDNLKKAVDDNEHFWKC-----LFLSIINSGDRKLGALFQNENILALLSSEARECVNPELITAMCKGLQDESIFVQRGFFDLLTSRLELRSDVIQKLASQSDKEKLLLTA...................................................................................................................................................................................................................................................... 269
36 -9.170PF08569.11; I1JJR7_SOYBN/4-337; Mo25-like  ali follow..  10  2................................................LFKPKPKTPVELVRHARELIIFLSNACTRESKREEKLSDLSKMILEIRTVLY----GESEPNADACSQITREFFKDDTFRLFILYLSNLKLGARQDATHVIANLQRQRVNSQLIANLDLVDMLIGGYEKEGDIALTYGAVARECIR-HQSVARHVLESEHMKKFFDYIQLPNFEIASDAVATFKELLTRHKSTVAEFLSKNFFKEYNSQLLESTSYFTRRYAIKLLGDMLLDRSNAAVMVQYVSSLDNMRILMNLLRDSNKTIQLDTFHVFKLFVANQNKPPEVVSILVTNKHKLLQFLDNFNNDKAD-KQQVISEIITL........................................................................................................................................ 333
37 -9.150PF12231.8; Q5BCS0_EMENI/131-504; Rap1-interacting factor 1 N terminal  ali follow..  12  1....................................................LAGESTSSRIDAYMQFFGALRAYEKLEEILHKMSLIAEFIQRDDTNLVIQALKLSVVLVWHPQISPQLPDELFLIEHSVVCLESENLSVVTHYLTVLSTQKFPARIITAARTTRILGMLHSITDKGNSVISQRLMIYERLFDVAKPTFLALSTL-WMDHLISGLLHQIKNVRLNALELGFNVYMASGSNSTLSKTSEVSERMSRMMSNPETGEHVPQIWGVITLLLRS--KRFNIDQWQHFKEWVLVLQKCFNCNDPEIKSKAIGNWNRF...................................................................................................................................................................................... 303

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Nika K, Tautz L, Saito K, Cerignoli F, Friedberg I, Godzik A, Mustelin T. Identification and characterization of DUSP27, a novel dual-specific protein phosphatase. FEBS Lett. 2007 May 29;581(13):2527-33. Epub 2007 Apr 30.