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Query: PF11719.8; A7ERI1_SCLS1/13-528; DNA replication and checkpoint protein, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst SKTLRVELKVWEKDFQNNNQGRKAAREDIKANPDIASKYKEFNKVRDILAGKISHIPPSAPKATPRKRRHEENHNETPQKRLLVDRTPSKNTMLPWDVDPYHSPSIMRNLFATPSKKMAIGPTPQKDGQVLGLFDLDPDSAADSPSTAHGTAGKLAATQSTPRKTGMTPGSTRAIMHSNTPSSRRTLLFSTPSKNKTAHDHGSNTPSSVSKLHFNTPSFLRRDSQRIRLPAVDENEEDPPDSPEMVRGPQRPMIKSLSSMLAGLRKMEEDAADDDLEALNQMEAEMANTSKSIPKPKPRLQETDSSNIPASKPPAKDSLPEDTSVVDSQPRELLGGFDDEAKYDSEPEEATNAHTSTFKKKGQKRTTRRVNLKPNRTKPSQPMPPTNHYDASESEDELALPDDHLETIPETQLDDEIPRPEDDEFPQPDEFLPDGRNFDSDSASEYTASEGGTRYRRPDQDKTKKSREVNKEGKVKKAARKVKATAGSLQNFKRLKLRNSGAKGGPGVGSRFRRRKLast
1 -149.000PF11719.8; A7ERI1_SCLS1/13-528; DNA replication and checkpoint protein  ali  100  1SKTLRVELKVWEKDFQNNNQGRKAAREDIKANPDIASKYKEFNKVRDILAGKISHIPPSAPKATPRKRRHEENHNETPQKRLLVDRTPSKNTMLPWDVDPYHSPSIMRNLFATPSKKMAIGPTPQKDGQVLGLFDLDPDSAADSPSTAHGTAGKLAATQSTPRKTGMTPGSTRAIMHSNTPSSRRTLLFSTPSKNKTAHDHGSNTPSSVSKLHFNTPSFLRRDSQRIRLPAVDENEEDPPDSPEMVRGPQRPMIKSLSSMLAGLRKMEEDAADDDLEALNQMEAEMANTSKSIPKPKPRLQETDSSNIPASKPPAKDSLPEDTSVVDSQPRELLGGFDDEAKYDSEPEEATNAHTSTFKKKGQKRTTRRVNLKPNRTKPSQPMPPTNHYDASESEDELALPDDHLETIPETQLDDEIPRPEDDEFPQPDEFLPDGRNFDSDSASEYTASEGGTRYRRPDQDKTKKSREVNKEGKVKKAARKVKATAGSLQNFKRLKLRNSGAKGGPGVGSRFRRRK 516
2 -9.530PF04931.13; K2SXE2_MACPH/89-879; DNA polymerase phi  ali follow..  11  642.........................................................................................................................................................................................................................................................................................................................................................................................DQQGSEDGEDASEDDEDEQDSDVEMVEADGSDVEEVEEASDVDEEEEEDEDEEGGEDGSDADDEELEKFNAALAKTLNTSMLTGEGEDSDDDDEADMDDDQMMALEPHLTK---FKQRQEAANKSKKKDNKDAKFKNR. 782
3 -9.020PF12737.7; A8N2T2_COPC7/197-610; C-terminal domain of homeodomain 1  ali follow..  9  1.....AEL---QFAFAQ-----------VTSNAR--TLYQKVSTLDSAVKDMTPELKRQLQSEKRKKLQGEQAAAAYPSPERSPLSLQTHLSPSVSAPSLPERTSPTGKRRLSPTIDSDDERAERSKKRPRLDAPATTPPPSKRVSNSLPSPALSECAALNEGLATVEDTPSTSAPVEVSKKRKRRLSESDGTPCRKRPQNADNRPRPVA----SDP........................................................................................................................................................................................................................................................................................................... 199
4 -8.610PF15895.5; CXX1_HUMAN/1-209; CAAX box cerebral protein 1  ali follow..  11  3...................GGRGLL-GRETLGPG--------------CSGEGPLCYWPPPGSPPAPSLRASLPLEPPRCPLRSCSLPRSACLCSRNSAPGSCCRPWASLWSEPPPSPSSQPAPPMYIWTLSCAPAASWAPVTHWTDHPLPPLPSPLLPTRLPDDYIILPTDLRCHSHRHPSHPTDRLLLLVIWTHLGGIWAGHSPWTVIQTAGRPPR.......................................................................................................................................................................................................................................................................................................... 188
5 -8.090PF05460.13; Q75D89_ASHGO/10-395; Origin recognition complex subunit 6 (ORC6)  ali follow..  9  6GLNAQEETPDWNSGRLKR--NVSLNKVMLKQPEEIARCH---EKLSEKYEPELQYYREKIPLEPRKTVKKQTLWTSSPVRNLNLSPSPKKDGGRLSARDPVELRAELFGTPVKRAGAVTLPGAGELSPTKQLSPSKPMSPVKPSPRRRLAFEDEDEDYEPDASPQPSPRRSIFPGGFEPDPDESEFDSPTKSPFKSPTRSPTKSAQSSPRKKRGEYNQ.......................................................................................................................................................................................................................................................................................................... 239
6 -7.480PF03035.14; Q917X0_9CALI/1-251; Calicivirus putative RNA polymerase/capsid protein  ali follow..  9  38....NRQLQ--QNSF--NHD-KEMLSAQIQATKQLQAD----GVLAAGGFSPTDAARGAVNAPMTQALDWSGTRYWAPGSMKTTSYSGKFVSMNPVRQVEFPQPKKSAAIPSSASSVSSGRTNLT---------STQSTVVSTSSAPPSRGSSAPSTLSRATTRTSNWVEEQNRNLEPYMRGALQTTFVTPPSSRASSNGTVSTVPKGVLDS--RQPLF......................................................................................................................................................................................................................................................................................................... 247
7 -7.180PF11516.8; Q7VSD3_BORPE/115-220; Protein of unknown function (DUF3120 topsan)  ali follow..  22  26SMALQGDVKVWEAQWAKQH-GTPPTASDVAGMPQ----WQEYTAM....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 95
8 -7.000PF07222.12; F5H5S8_HUMAN/1-240; Proacrosin binding protein sp32  ali follow..  10  61..RLRAQLDQYE------NHGLVPD-SNLPYASWFESQFTHYRCSNHVYYAKRVLCSQPVSILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKE....................................................................................................................................................................................................................................................................................................................................................... 240
9 -6.980PF11774.8; U5WB95_9ACTN/1-114; Lsr2  ali follow..  16  84....NQAIREWKNGYEVSERGRIPS--------SIVEAYHS........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 114
10 -6.760PF14181.6; YQFQ_BACSU/70-247; YqfQ-like protein  ali follow..  8  45.ASLSSMLGNVQKVLGMAQQ---PMIQQVRNLPAMMKLYSQLSKSDDTETEANEESEKQSVSEESSEKEKETETKTSDGNKKSKPKSSSLPKKSKTTDNKEQELKTSAPKKKEAASPAP--SKPR....................................................................................................................................................................................................................................................................................................................................................................................................... 175
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.