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Query: PF12126.8; I3MLB7_ICTTR/239-567; Protein of unknown function (DUF3583 topsan), from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst LDTMAHALQEQDSTFSTAHAEMRSAIGQLGRARADTEELISTHVRQVVAHVLARERELLDAVNEQYQRDYQEMASQLRRLDAVLQRIRTGGALVQRMKRYASDQEVLDMHDFVHKALNRLRQEEPQSLQAALHTDGFEEFKIRLQDFISCITQGTDAAVCRRASPETAGTPREPFDVDLPDEAQRVQAQALGLAEAQPVAVVQSVPGAHPVPLYAFSIKGSSYSEEVSNTTTPQKRKSCHTQCSRKVIKLESEEDKEARLASSSPEQARPSTSKAVSPPHSDGPPSPESPIIGKEVLLPNNNHVLGDTGEAEERIVVISSSEDSDAENSLast
1 -73.100PF12126.8; I3MLB7_ICTTR/239-567; Protein of unknown function (DUF3583 topsan)  ali  100  1LDTMAHALQEQDSTFSTAHAEMRSAIGQLGRARADTEELISTHVRQVVAHVLARERELLDAVNEQYQRDYQEMASQLRRLDAVLQRIRTGGALVQRMKRYASDQEVLDMHDFVHKALNRLRQEEPQSLQAALHTDGFEEFKIRLQDFISCITQGTDAAVCRRASPETAGTPREPFDVDLPDEAQRVQAQALGLAEAQPVAVVQSVPGAHPVPLYAFSIKGSSYSEEVSNTTTPQKRKSCHTQCSRKVIKLESEEDKEARLASSSPEQARPSTSKAVSPPHSDGPPSPESPIIGKEVLLPNNNHVLGDTGEAEERIVVISSSEDSDAENS 329
2 -8.180PF15921.5; G5BJQ7_HETGA/1-1111; Coiled-coil domain-containing protein 158  ali follow..  9  732..GMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFL-KNKLSQELSTVATEKNKMAGELEVLRSQE-RRLKEKVANMEVALDKASLQQDIIQRQ-----EQESVRLK--LQHTL-DVKELQ............................................................................................................................................................................................................. 850
3 -7.030PF07267.11; Q2NNY4_NPVHC/1-628; Nucleopolyhedrovirus capsid protein P87  ali follow..  8  1.....................MDEQDNSLRIVTLAGHILTRDRAAINVQALGQKFDAIKTFVDSLKPGALLENERQINSVDSIMRHLQIAVAFLRRALMVGAPQVTLNIQNLLNDYETHVKKDILDETVIEGFLNNASALYNELRD--NNILPFIKNAEKQAPSRTEKEKPSLEQMVQTPLPPTGEKELQQEIIASPPVIRNEQDFDKLNIRQLSDYINRNNRKLLNYTAAHESVDDVRNFAKAVWRANNAPDYTEQTPMPEQSWQSPQQTPAYTEQTPMPEQSWQSPQQTPAYTEQTPMPEQSWQSPQQTPAYTEQTPMPEQGWQSPQ 319
4 -7.000PF08549.10; E3Q6J3_COLGM/3-717; Fungal domain of unknown function (DUF1750 topsan)  ali follow..  9  317LASLTDGIFPAQSADALTEPPQKPYIGRLEPGLA---DEFRKRVREHLDATKAE----MEKMKAEHAKNLASLK-ASSVFVDAEKDIKNSVQ--------EHGPEPWRIEGHYTDS------EDNSGPWSQKHNKKVDEIVAQVEANLGRQIEVLHNVHRIQDGGFQEPAPEPVKE---PSPVPPPASSLPPAAGADTGALGSRRPSQAGSTHSGVMVGDSDIDMGGTAAGLLDEMHTGFSANSTPLNNFPTPQTHMSALNSTAGTPANANAPSPAPVPPTIPEETETQASAGASAGAAEDVTMGNTGSTKNTPATAPDHGTGSGEWVV 620
5 -6.990PF10168.9; I3KZS6_ORENI/8-718; Nuclear pore component  ali follow..  11  562VKLLTGQKNKQLEELSLCREERKSLREAAERLADKYEDAIMNRVKKVLCSLQSQLPIL-SNSEKEMKKELQTINDQLKHLDNCIRQVNMKMEYQKTQVD--NAPQKKVVQDVLKEQGQQI-----------------GDMMKQIKDIKNHFS................................................................................................................................................................................. 711
6 -6.920PF10428.9; H6C681_EXODN/477-953; RAM signalling pathway protein  ali follow..  9  5LSSLPEH-KVEQEWKSPIIEGAKGILYALYQVHPQISGLIRSTLEFTFFNASTHVDRLNEALEQVDMVDPEDEDAVEKIESTVQRDCATCAQLQDNVKKIVAVIDARYVRTLM-GSMAEVRNA----------------------QSFGADVKVTQGLGHRRQMSSGNTHPIQTIPEEFSTPSQPVRASTPTRDRHWPSRQIGRLRSDTAIQHAVVETNPGHQPNSVPPANTAVFPTPIQLSGSTLNGGLPTGTSTTFSNSGTMASSSTTSGLRSRSSSRNAQLINGLGSSSLASTPRSGEGFSLPQSTAYGVRVNPSTGLTDAHEEAV 331
7 -6.900PF10191.9; Q7QA49_ANOGA/2-731; Golgi complex component 7 (COG7)  ali follow..  16  16INASYERSQKTATGSVGKEAFVSSLVSKMQLYVQQINVALEQTGGQVANMLQIESGLLKQRMNAHLQTETGDCMVSLERLDDIKQRLQSSKQCLQEADGWGK-DDLLEKSDISSGKLLSLQK----SLAAQVGLHGHSERENLVEYFKNRLEA................................................................................................................................................................................ 186
8 -6.820PF07139.11; SPAS2_HUMAN/81-385; Protein of unknown function (DUF1387 topsan)  ali follow..  11  152........KKLSSNIEKSVKDLQRCTVSLARYRVVVKE-MKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAVQM--------SEQQLVELRADIKHFVSERKYDE............................................................................................................................................................................................................. 266
9 -6.660PF11887.8; A1T3L0_MYCVP/145-410; Cholesterol uptake porter CUP1 of Mce4, putative  ali follow..  11  19LSALAEGLRGQGPAIGEATTAANEVLHALNPRSDTVRADWQS-LAAASETYSDAAQDIMAVLDSFTT--AVTLDEQSSALDALLVNAAGLARSGIDLL--VSKDDFVHTVNTLEPTTGLLEKYSPS........................................................................................................................................................................................................... 141
10 -6.460PF11593.8; MED3_YEAST/3-397; Mediator complex subunit 3 fungal  ali follow..  8  8....................KLDDLQVILAKNENETRDKVCKQINEAILPLRLQFNEFIQIMANIDQEGSKQADRM------------------AKYLH-------------IRDKILQLNDR----------FQTLSSHLEALQPLFSTVPEYLKTADNRDRSFQLLEPLSTYNKNGNAVCSTATVVSTNHSAAASTPTTTATPHANPITHAHSLSNPNSTATMQHNPLAGKRGPKSGSTMGTPTVHNSTAAAPIAAPKKPRKPRQTKKAKAQAQAQAQAQAQVYAQQSTVQTPITASMAAALPNPTPSMINSVSPTNVMGTPLTNMM 278
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Rychlewski L, Ye Y, Jaroszewski L, Godzik A. Integrated web service for improving alignment quality based on segments comparison. BMC Bioinformatics. 2004 Jul 22;5(1):98.