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Query: PF12530.8; D8SAX6_SELML/484-706; Protein of unknown function (DUF3730 topsan), from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst LFSLKYHQRHDVNTNVVIAFLNALPDICGHPTTVPLSMHLLQHMVDYKGNLRIQATSIRLIYKIWQHTDRAYSFLQKTLVPSWFSQAKEETDVLLSRATSLRDLCGHDPDVGIELILSVQACVECRSPVVKALGLQSLSFLCGHDAIDFYTAWKVIAKLFSPLPISPSISESFCMLLKHGALDANLNAEDAHAVLNALWEFASCDKQPSEEWYRTRSAAVESLLast
1 -84.300PF12530.8; D8SAX6_SELML/484-706; Protein of unknown function (DUF3730 topsan)  ali  100  1LFSLKYHQRHDVNTNVVIAFLNALPDICGHPTTVPLSMHLLQHMVDYKGNLRIQATSIRLIYKIWQHTDRAYSFLQKTLVPSWFSQAKEETDVLLSRATSLRDLCGHDPDVGIELILSVQACVECRSPVVKALGLQSLSFLCGHDAIDFYTAWKVIAKLFSPLPISPSISESFCMLLKHGALDANLNAEDAHAVLNALWEFASCDKQPSEEWYRTRSAAVESL 223
2 -11.500PF17741.1; A0A151PBS4_ALLMI/1-268; Family of unknown function (DUF5578 topsan)  ali follow..  10  105VLTLLEILGSQLKEEDKKESIKLLQLVANAGRKYKELIRSIAEFMASSKSEKAQRQVQILLDSLGHGNPKYQNQVYKGLIALLPCTSP---HAQQLSLQTLRVVQAIVGKSHPSIVEAVLGVLRSMELEVQYEAIQLIKDLTSYDV-------------------RPALLRGLVALLK............................................. 267
3 -11.000PF04826.13; ARMX3_MOUSE/110-363; Armadillo-like  ali follow..  10  14LQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIILPIVAKILN-TRDPIVKEKALIVLNNL-SVNAENQRRLKVYQVCDDTVTSRLNSSVQLAGLRLLTNMTVTNEYQ-ANSISDFFRLFSAGNEETKLQVLKLLLNLAENRELLRAQVPSSLGSLFNKKEYKEVILKLLIIFENINDNFKWEENEPAQNSEGSLFFFLKEFQVESRHDFQVRVKV.... 253
4 -10.900PF12717.7; G8Y240_PICSO/105-271; non-SMC mitotic condensation complex subunit 1  ali follow..  14  2....................................................IRALAIRTMGCV--RVARMVDFIEIPLKRTLSDDNP----VRKTAAICVAKLFDLSPKACVEFLDQLRGLIKDSNPMVVANALNSLFEIKDMNVDSSLVVLEFDSELIKTLLMCLNECTEWITILDTLTKYEASSSEEASHIIDRATPQLQHANPS------VVLSSIKVI 165
5 -10.700PF10508.9; A7SP09_NEMVE/2-505; Proteasome non-ATPase 26S subunit  ali follow..  13  87...AVIEGLNHPTEDVRELCLIELERCSGTVNGVLALMDLLSYIARADEHLKNAQIASNVFTNLAKHEAGLKVLFDSHLQSEFNALLKTKDTVRMRVYDMYITVQAHSPKKESGIFEKLISELDGRDVLVQMNCLELLTKLASIEYLDQKGVVTKLNNLLLEVETDPLITLIIPGIIKFFGTLATAHPLETTQQYPQFLEQTYSM---SCGDPTLMPIAMETI 319
6 -10.300PF03542.16; A0A088ADA5_APIME/557-907; Tuberin  ali follow..  11  135CKAVISCIKLEKDWKVLQLVLKELPQVMQNR-----------ALILSRHTNDIDYFANALCSMVSDKSLRLPESLYNV------PPKFTLSEFRVHVFPVLASLASYEPNLQQRLIKCLEVGLTAKCASQ---CVTSLTTCILEMRDAMNKLLSEVLLNLSKISATVHIAIPILEFLSTLTRLPKVFASFIGDQYMSVFAILLPYTNPFKYDHYTVSLAHHVI 341
7 -10.000PF12719.7; M3XT68_MUSPF/558-858; Nuclear condensing complex subunits, C-term domain  ali follow..  4..............ILCYELLKQMSTSTGIGATMNGIIESLILPGIVSVHPVIRNLAVLCLGCCGLQNQDFASKHFVLLLQVLQIDDV---TIKISALKAIFDQLKEETATAKNVLKLLSDFLDSEVSELRTGAAEGLAKLMFSGLLVSSRILSRLVLLWPVTEEDVRLRHCLGVFFPMFAYASRTNQECFEEAFLPTLQTLASAPASSPLAEVDITNVAELL 244
8 -9.820PF05918.11; D7TJH2_VITVI/11-547; Apoptosis inhibitory protein 5 (API5)  ali follow..  3..................KLYEYGERLNEAKDKSQNVEDYRGIIAAAKGSIKAKQLAAQLIPRFFKFFPDLSDAAVDSHLD-----EEEELGVRVQAIRGLPLFCKDTPEYVSKIVDILAQLLTAEENVERDAVHKALLSLLRQDVKASLTGLFKHIMTVDDPSTDENLREKVLNFIRLKAELLKPQEQMERHITNLIKKSLEDVTGAE.............. 195
9 -9.250PF01347.22; VIT_ICHUN/18-588; Lipoprotein amino terminal region  ali follow..  11  333........KLHQQKDYRRWILDAVPAMATSE-----ALLFLKRTLASEQLTSAEATQVYSTLSNQQATRESLSYARELLHTSFIRNRPIRKTAVLGYGSLVFRYCANTVSCPDELLQPLHDLLDRADEEEIVLALKALGNAGQPNSIKKIQRFLPGQGKSLDEYSTRVQAEAIMALRNIAKRDPRKVQEIVLPIFL-----------NVAIKSELRIRSCIVF 537
10 -8.690PF05804.12; KIFA3_HUMAN/13-720; Kinesin-associated protein (KAP)  ali follow..  414IPQLMKMLFECSDERIDLELISFCINLAANKRNVQLILKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQIS---NDEEEEFVIECLGTLANLTIPDLDKEYKLVPYLKDKLKPGAAELVLEVVIMIGTVSMDDLLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQATRDVIIKEAPAYLIDLM------HDKNNEIRKVCDNTL 645

FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 8 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.