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Query: PF12849.7; B6YQR6_AZOPC/32-299; PBP superfamily domain, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst DSTTGDTLSGKVRISGSFALYPMMVKWAETFKILHPDVSFDISGGGAGKGMTDVLNEMVDVGMVSREIYSQEVENGAFCILVAKDAVVPIVNVANPELKAILSIGLRKEIARKLWNEKIKTWGAVLGTSSKTCVHVFTRSDACGAAETWASWFNARQEDLKATSIFGDPGIADAIQKDKFGIGYNNISYAYNRKTKKLNEGLAIIPLDVNGNGKIDPEESFYETMESLITAINDGRYPSPPARYLYLVTKGKPTSPALISFLKYILSELast
1 -107.000PF12849.7; B6YQR6_AZOPC/32-299; PBP superfamily domain  ali  100  1DSTTGDTLSGKVRISGSFALYPMMVKWAETFKILHPDVSFDISGGGAGKGMTDVLNEMVDVGMVSREIYSQEVENGAFCILVAKDAVVPIVNVANPELKAILSIGLRKEIARKLWNEKIKTWGAVLGTSSKTCVHVFTRSDACGAAETWASWFNARQEDLKATSIFGDPGIADAIQKDKFGIGYNNISYAYNRKTKKLNEGLAIIPLDVNGNGKIDPEESFYETMESLITAINDGRYPSPPARYLYLVTKGKPTSPALISFLKYILSE 268
2 -20.200PF12727.7; A0LFW2_SYNFM/425-616; PBP superfamily domain  ali follow..  12  1...........................ANEIKRRDGRMQLSSGNVGSLGGLMAVRRAQTHLAGSHLLVERYLQGVPIRLVTLAVRQQGLLVRRGNP---------AGVRGVRDLARPD---------------VAFINRQGGSGTRILFDYCLRKEELAPEEIEEFTHMAIAVTVLSGRADAGM---------------------------------------AIFAAARALGLDFIPVAEERYDLVIPESFWEDPKMGLLMEII... 191
3 -14.900PF01547.25; CYSP_ECOLI/33-278; Bacterial extracellular solute-binding protein  ali follow..  10  2.................DVSRELFAALNPPFEQQWAKLTIKQSHAGSSKQALAILQGKADVVTYNQVTDVQILHDK--NSSPFYSTMGFLVRKGNP--------------------KNIHDWNDLVR--SDVKLIFPNPKTSGNARYTYLQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFESEVNNIRKQYEAQGFEVVIPKTN-------------------------EFPVAW---VDKNVQANGTEKAAKAYLNWLYSP 242
4 -10.400PF13531.6; A9BZ83_DELAS/51-277; Bacterial extracellular solute-binding protein  ali follow..  9  1...........IRVVTSGGFSAAYDQLIPLYEQAT-GHKVVTSRGASMGNAQDSIPSRLDIVILADGALDNLAAQGKVRVDLARSMIGMSVRKGTPKPDISTVDALKQTLLDAK------------------TIAYSASASGTYLANELFPRLGVAEQMKGKATRILSERVGAVVLRGDADIGFQQVSEL------LPFKELEFV-----------------------------GPLPDEVQQRVFFVATGAKSPETARHLIRFLAAP 216
5 -8.370PF03466.20; Q98I60_RHILO/88-294; LysR substrate binding domain  ali follow..  13  1....KDRPSGVLRVTGAGWLTERVQ----EFIELYPEISLQLILANE---ELDLTMRQADCAIRLRQPQQPDL-------------------IQRRLFTVHFHLYAAPSYVAK--HGKPASVSEL----RNHRIVTFGLPVPSHLSELNWLETVGDFEGGQRVPSLQINDILSIKRAVQGGAGIAMLPDYVINKDSGL---VQLLP-----------------------------ETEVPSFDTYFAYPDAMKNQAKLHVFRDFIIAK 205
6 -6.150PF01451.21; PAP_BACSU/3-142; Low molecular weight phosphotyrosine protein phosphatase  ali follow..  7  3...........FVCTGNTCRSPMAEALFKSIAERE-GLNVNVRSAGVFAAVEALFEKHIALNHVSSPLTEELMESADLVLAMTHQHKQIIASQFGRYRDKVFTLK-SHGDVLDPFGGSIDIYKQT............................................................................................................................................... 128
7 -6.070PF14737.6; G0REV6_HYPJQ/109-210; Domain of unknown function (DUF4470 topsan)  ali follow..  11  3...............GNHAATDILNLAENEGAEYDGFLRLLLLGPFGLRHLIYSVAAMPETANPLINVVICETDFSQ----LLRTIISLHIMVSWR-QDPEENTALIAEIVSHVWYS--LKW.................................................................................................................................................. 102
8 -5.910PF13995.6; J7SK57_MORMO/37-124; YebF-like protein  ali follow..  8  3............................................................................................VTFPACESLNKDQIAAQVKYDFVQSRYPRWQDDKALLGSKPVAWVNVAEVTEKDGNYS--------PLVVRGSKKQVSYTVDINCAAKTMTYS................................................................................... 88
9 -5.890PF08804.10; H8FY95_PHAMO/30-218; gp32 DNA binding protein like  ali follow..  4  2..............PGKSRWRILPTWKKDGDPTFFHEFGQHFIKDQTGELKAVYVCTDKTFGKPCSSATDDDLIKALTEAKSKTRYLLNAIQPDGENAGEVVILDLSPTTFEKILDVMEEHGAEMIDPDAGIDIII--ERKGKGLNTEYSVVPAAKSKPVNKTLLAQLNDLDAYVNQEY......................................................................................... 174
10 -5.890PF15306.6; V8NWJ9_OPHHA/156-315; LIN37  ali follow..  7  25............QFSENTPLYPICRAWMRNSPMVREQERSPSPNLPTLLEDEEGVEVLNGKIQDVYKLPSPIPCQTNPAGEPINLRIPFRPASEEETKVAAETTSEAVPSMSTLIYKNMDRWKKIRQRWKEASQKNQLRYAES............................................................................................................................. 155
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.