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Query: PF13847.6; B2J9C6_NOSP7/55-253; Methyltransferase domain, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst DTKEKVILDAGCGTGYKSLVLAEANPGAKIVGIDISEESIKLAQQRLEHHGFDNAEFHVLPIQELPKLNYQFDYINCDELLYLFPDLAAALQGMISVLKPNGIIRSNLHSSIQRFPYFRAQKVFTMMGLMDENPQDLEMEIVVETMKALKDNVELKARTWNPNKYEGENGKEGILMNYLFQGDKGYTISDMFTALKAADLast
1 -80.400PF13847.6; B2J9C6_NOSP7/55-253; Methyltransferase domain  ali  100  1DTKEKVILDAGCGTGYKSLVLAEANPGAKIVGIDISEESIKLAQQRLEHHGFDNAEFHVLPIQELPKLNYQFDYINCDELLYLFPDLAAALQGMISVLKPNGIIRSNLHSSIQRFPYFRAQKVFTMMGLMDENPQDLEMEIVVETMKALKDNVELKARTWNPNKYEGENGKEGILMNYLFQGDKGYTISDMFTALKAAD 199
2 -46.000PF13649.6; D8K355_DEHLB/33-128; Methyltransferase domain  ali follow..  31  1......VLDVCCGTGDQAIRLAEQ--GIEVHGIDLNGSMLATAESHKRRAGLDNVSFGQADASALLFPNRSFDYATTSLALHEKPREVQVLEEMRRVVKKGG................................................................................................. 96
3 -40.900PF08003.11; CMOB_VIBVY/7-322; Protein of unknown function (DUF1698 topsan)  ali follow..  19  114PLKNRSVLDVGCGNGYHMWRMLGEGA-RLCVGIDPSHLFLIQFEAIRKLMGGDRAHLLPLGIEQLPK-LEAFDTVFSMGVLYHRRSPLDHLIQLKDQLVSGGELILETLVIEGDETAVLVPKER-------AQMRNVYFFPSARALKVWLELVGFEDVRIVDENVTSVDEQR--LPDYLDQNDPSKTVEGYPAPRRAI. 311
4 -40.200PF08241.12; Q83DM1_COXBU/77-169; Methyltransferase domain  ali follow..  25  1.......LDIGCAKGFLVKDFMKACPGLEAYGIDISEYALMNCEPEVV------GRLHLGNADHLPFPDNSFDAVISLNTVHNLPRERIALREIQRVSGGKAYI............................................................................................... 93
5 -35.600PF06080.12; Q8YZS2_NOSS1/8-210; Protein of unknown function (DUF938 topsan)  ali follow..  20  23.PASGTILEIASGTGEHAIFFAPRLKPRKWLPSDPNPELRASITAWIAQFPSDNYPPVELDARDAILQDAPIAAIVNINMIHISPWSAGLLAGAGRILPPGGILYL............................................................................................. 138
6 -34.700PF03291.16; MCES_YEAST/109-424; mRNA capping enzyme  ali follow..  22  55.KPGDVVLELGCGKGGDLRKYGAAG--SQFIGIDISNASIQEAHKRYRSMRNLQVVLITGDCEPFPDCRFPCDIVSTQFCLHYAEKARRALLNVAKSLKIGGHFFGTIPDS........................................................................................ 178
7 -34.700PF01170.18; Q9RTT7_DEIRA/193-364; Putative RNA methylase family UPF0020 topsan  ali follow..  20  28..DEDRIFNPMSGSGTLLIERALLGPYAALVGVDIDPVAVACARTNLRAAGK-EVEVAQVDALHTGLPSRSFDLVISDLPWGDAIGSPAFLKEMHRLTSRRGRLCLLT........................................................................................... 140
8 -34.300PF07091.11; KRM_FRACC/28-281; Ribosomal RNA methyltransferase (FmrO)  ali follow..  12  107..TPAVVQDLACGLNPLAFGSMGLPAQTTYLASDIDSQQMEFLDRALDLLEV-EHRVEVVDLVSGAVPAQHADVTLVLKTLPLLERQRAGGWELVDALRSPFVVV.............................................................................................. 209
9 -34.200PF05401.11; Q98A39_RHILO/5-200; Nodulation protein S (NodS)  ali follow..  23  37QGRVANALEVGCAAGAFTERLAPICQ--RLTVIDVVEPAITRARLRMK--ETPHISWIISDVQQ--SSDELFDLIVVAEVLYYVGDLVAAVRNLVGLLAPGGQLVFGSARD........................................................................................ 145
10 -34.100PF05219.12; METL9_HUMAN/56-317; DREV methyltransferase  ali follow..  19  88DWKTHRLLDLGAGDGEVTKIMSPHF---EIYATELSETMIWQLQKK---------KYRVLGINEWQNTGFQYDVISCLNLLDRCDQPLTLLKDIRSVLEPTRGRVILALVLPFHPYVENVGGKWEKPSEILEIKGQN-WEEQVNSLPEVFRKAGFVIEAFTRL.................................... 238
11 -33.000PF03848.14; TEHB_HAEIN/91-282; Tellurite resistance protein TehB  ali follow..  19  29.ISPCKVLDLGCGQGRNSLYLSLLG---DVTSWDHNENSIAFLNETKEKENL-NISTALYDINAANI-QENYDFIVSTVVFMFLNRERSIIKNMKEHTNVGGYNLIVAAMSTDDVP................................................................................... 141
12 -32.200PF01209.18; COQ5_YEAST/56-306; ubiE/COQ5 methyltransferase family  ali follow..  18  56..TPLNFIDVAGGSGDIAFGLLDHAEESTMDIVDINPDMLKEGEKRAMEQGKPRVRFLVSNGEKLEIDSDSKDIYTVSFGIRNFTDIQKGLNTAYRVLKPGGIFYCLEFSKIENPLMDFAYQQWAKVDSYQYLVESIERFPDQETFKSMIEKAGFKSAGYESLT................................... 240
13 -31.900PF05148.15; RRP8_CAEEL/125-343; Hypothetical methyltransferase  ali follow..  21  72..DQQSVFDLGCGEAKIAEAVG---EKHKIRSFDLVA---------------VNDRVESCDMSKLPAEDSSADIVIYCLSLMGT-NLYDFIREARRVLKIGGILKIAEVTS........................................................................................ 161
14 -31.800PF13679.6; Q12FV8_POLSJ/56-202; Methyltransferase domain  ali follow..  16  25..PAPTLADHGAGKSYLGFILYDRKDAGHIYGIETRTELVDKSRALAARLGFERMSFLNLSVQQATASADLPERIDIVTALHACDT--ATDDAIAFGLAKQARHMVLV........................................................................................... 137
15 -31.700PF12147.8; Q2K5I6_RHIEC/285-593; Putative methyltransferase  ali follow..  16  133..RSTHLLDIAAGHGRYVLDAIEAAGPDSARLQDYSPINVDAGRNSIARRGLNDVSFHQQDAEGLAAITPAPDLAIVSGLYELFSDNAASLSGIARAMQPGGLLIYTNQPWHPQLEMIA-----RALTSHRGGQAWVMRRRTQEEMDQLVAAAGFRKLEQR...................................... 295
16 -31.200PF03269.14; A0A2H2IKF9_CAEJA/181-356; Caenorhabditis protein of unknown function, DUF268 topsan  ali follow..  9  1...GQSGVVIGSMQPWVEVSALVNGAK-KILTVEYNKLTIQEEFRDRM-----SSILPVDFAKGWANYADTFNFAASFSSIEHSGGDIREILKIKCVLKKGGLLFLGF........................................................................................... 110
17 -30.700PF01269.17; A8M8R8_CALMQ/9-236; Fibrillarin  ali follow..  11  71..EGSKVLYLGAASGTTVSHVSDIGLNGLIYGVEFSPRVFREFMQNIIDQGRLNVIPILADARYPEQYISLVKGVVAYIDVAQPFQAKILADNADVYLVKGGYIILVIKAM........................................................................................ 181
18 -29.700PF13489.6; C5G7B3_AJEDR/109-340; Methyltransferase domain  ali follow..  19  28.....NVLEVACGTGRNKKGKAEIQGCRSVTFVDQSPQMVEIAREKFEKMYPRKAISLQTPEICAQQQSGKFDTVIQTMGLCSLPDPVSYLTHLGTLVEPRGEILLLEHGRSHYRWLNKLLDDLA.......................................................................... 203
19 -28.700PF03141.16; PMTB_ARATH/186-689; Putative S-adenosyl-L-methionine-dependent methyltransferase  ali follow..  20  115GKHIRVAMDVGCGVASFGAYLLSRDVMTSVAPKDVHENQIQFALER----GVP-AMAAAFATRRLLYPSQAFDLIHCSRCRNWTRDDGILLLEINRMLRAGGYFAWAAQP......................................................................................... 221
20 -28.700PF07021.12; Q89UL6_BRADU/24-217; Methionine biosynthesis protein MetW  ali follow..  19  13..PGSKVLDVGCGDGDLLQLLETR--GIDGRGIELSREGVNRCVAKGLAVVQGDA-----DTDLVNYPDDAFDYVILSQTLQATRQPRVVLENL---LRIGRRAIVSF........................................................................................... 108
21 -28.500PF09243.10; Q2YRR8_BRUA2/49-320; Mitochondrial small ribosomal subunit Rsm22  ali follow..  11  31EFAPQSMLDVGAGPGTALWAAKQCWPEQSATMIEASPAIRAVGSDLARHSGLTMLDWRAGDVVRERLEFPYADLVTIAYVLDELAPDEREKLIERLWASARQMFVIV............................................................................................ 138
22 -28.300PF05891.12; NTM1_ORYSJ/61-283; AdoMet dependent proline di-methyltransferase  ali follow..  17  54.RRHLVALDCGSGIGRVTKNFLLRHFN-EVDLVEPVSHFLEAAQENLTECMEVGANFYCVPLQDFTPDEGRYDVIWIQWCIGQLPDDDSFFNRAKIGLKPNGFFVLKENIARNGFVL---------------DKEDNSITRSDAYFKELFKKCGLYIHSIKDQS................................... 208
23 -28.200PF03059.16; A3DUI9_MALBX/3-277; Nicotianamine synthase protein  ali follow..  9  117.RMPIKIAFVGSGPLPLTVLASNHLTKTSFDNYDINASANSKALGLVSSDP-KRMVFHTTDIMDVTTALKDYEIVLAALVGMDKMEKLKIIDHLAKYMAPGATLML............................................................................................. 226
24 -25.000PF11968.8; A1C9Q5_ASPCL/61-283; 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2  ali follow..  10  51.PFKLRMLEVGALSTKNACTRSYLF---DVTRIDLNSQEPGILKQDFMKRPLPRAD------------NDRFHIISLSLVLNYVPSAIDMLKRCVEFLTDKLPSGLSL------------NIRPNLFLVLPLACVKNSRYLTEGRLQDILSSMGFVLAKSKETS................................... 189
25 -24.100PF08242.12; MLCA_PENCI/1437-1538; Methyltransferase domain  ali follow..  24  1.......LEIGLGTGIATKRVLASPQLNSYTCTDISADVIGKAREQLSEFD-GLMQFEALDINRSPFKPHSYDLIIASDVLHASSNFEEKLAHIRSLLKPGGHL............................................................................................... 102
26 -23.900PF01861.16; Q8U1U4_PYRFU/105-348; Branched-chain polyamine synthase A C-terminal domain  ali follow..  18  42DLENKDIFVLGDDDL-TSIALMLSGLPKRIAVLDIDERLTKFIEKAANEIGYEDIEIFTFDLRK-DYALHKFDTFITD---ETLEAIRAFVGRGIATLKGPRCAGY............................................................................................. 147
27 -23.800PF01234.17; INMT_MOUSE/1-260; NNMT/PNMT/TEMT family  ali follow..  12  54GVGGDVLIDIGSGPTIYQLLSACEVFR-EIIVTDYTPQNLQELQKRRTVTRVLRCDVTKTPPLG-SAQVPLADCVLTFLAMECADTYRAALRRLAGLLKPGGHLVTL--------------VTLRFQHYMVGPKKFSGVYLEKEVVEKAIQDAGCQVLKCNCVSLSYSEAYCSHDGLCFVVARK............... 260
28 -23.700PF02390.17; TRMB_DROME/71-251; Putative methyltransferase  ali follow..  18  1..QQVSFADIGCGYGGFLVTLGEMFPEKLSIGMEIRVKVSDYVVDRADTGAYQNIACLRTNAMKY-FVKGQLEKMFF-----LYPDPQALLSEYAYILRKGGLLYTMT........................................................................................... 125
29 -23.200PF03686.13; Y73A_ARCFU/3-126; Uncharacterised protein family (UPF0146 topsan)  ali follow..  10  10ENYRGKVVEVGIGRFTAVAELLAR-RGFEVFATDVVERRAP-----------EGCRFYVDDVTKPNLKIEGASLIYSLRPPPELFSAIVEVSR-----KVGADCLIKPLY......................................................................................... 103
30 -22.800PF02353.20; CMAS2_MYCTU/12-298; Mycolic acid cyclopropane synthetase  ali follow..  15  60.EPGMTLLDIGCGWGSTMRHAVAEY-DVNVIGLTLSENQYAHDKAMFDEVDSPRKEVRIQGWEEF---DEPVDRIVSLGAFEHFADGAGDFKKFYNLTPDDGRMLLHTIT......................................................................................... 174
31 -22.700PF07942.12; Q6L536_ORYSJ/216-485; N2227-like protein  ali follow..  11  54KERPPSCLVPGAGLGRLALEISTLG--FVSQGNEFSYYMMICSSSSGITEGFSMCAGDFVEVYNEESQESSWDAVVTCFFLDTAHNIVEYIEIISKVLKDGGVWI-------------NLGPLLYHFADSYGPDDDMSIELSLEDVKRVAYHYGFVMEVEKMIDTTYTANMKSMMQNRYRA.................. 261
32 -22.100PF05175.14; A6WWW0_OCHA4/169-336; Methyltransferase small domain  ali follow..  18  26KIFFGNVADLGAGWGYLAAQCLKFADRKSIDLYEADYEALEAARGNLERLGASPISFNWFDVTS-EKMAGIYDTVIMNPPFHE---GQAFIAAAASRLKPGGRLLMV............................................................................................ 138
33 -21.300PF05724.11; TPMT_VIBCH/2-217; Thiopurine S-methyltransferase (TPMT)  ali follow..  17  37..RSEKVLVPLCGKSEDLIWLANQH---SVQGVELSQIAVRSFFAEHFYTPTDELTLFTGDFFTAP--VESVDLVYDRAALVALPEEMRAAQRVLQLLKPGGRILLVSMD......................................................................................... 155
34 -21.000PF09445.10; Q6CRW0_KLULA/100-266; RNA cap guanine-N2 methyltransferase  ali follow..  18  1...GNCIVDVFCGGGGNTIQFARLFE--KVYGIDSNIDHLYCAYKNAECYNSVKLKLIYGDWEESKNLGKTPDCIFASPPWGGVDYLRQDTYDLEEHLQPSPLSKIL............................................................................................ 109
35 -20.500PF01135.19; PIMT_CAEEL/8-220; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)  ali follow..  15  71..AGAKALDVGSGSGYLTVCMAMVGRNGTVVGIEHMPQLVELSEKNIRKHHSENVIIIEGDGRQGFAEKAPYNAIHVGAASKGVPK------ALTDQLAEGGRMMIPVEQVDGNQVFMQIDK............................................................................. 190
36 -19.900PF01189.17; RSMB_ECOLI/239-427; 16S rRNA methyltransferase RsmB/F  ali follow..  20  8..NGEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQCGEQQFDRILATGVIRRHPDQSEILDAIWPHLKTGGTLVYATCSVLPEENSLQIKAFLQR......................................................................... 154
37 -19.800PF06325.13; PRMA_STRA5/3-308; Ribosomal protein L11 methyltransferase (PrmA)  ali follow..  16  169..GGETVIDVGTGSGVLSIASSLLGAK-DIYAYDLDDVAVRVAQENIDMNPGENIHVAAGDL--LKGVQQEVDVIVANILADIL---IHLTDDAYRLVKDEGYLIMS............................................................................................ 268
38 -19.700PF11599.8; A0A0J1DJF7_9FIRM/1-235; RRNA methyltransferase AviRa  ali follow..  16  51GKVPLTIYDPCCGGAYLLTTIALLHGREKLYASDVDGEILELAKANLALLTPAGMARRIAELEELKIAPQSIDIVITDVPYGSIASWSQDLSNLRPAVRDQGVVALVT........................................................................................... 213
39 -19.400PF08704.10; Q6DFS3_XENTR/64-300; tRNA methyltransferase complex GCD14 subunit  ali follow..  14  40..PGSVVCESGTGSGSLSHAIIRTAPTGHLYTVEFHQQRAEKAIEEFRQHKVHLVTVKNQDVCKHGFVTGIADAVFLD-----IPSPWEAIGHAKSAMKSEGGRICSFSPCIEQ..................................................................................... 149
40 -19.100PF02527.15; RSMG_HAEIN/20-200; rRNA small subunit methyltransferase G  ali follow..  20  45.LQGDRFIDVGTGPGLPGLPLAIINPSKQFVLLDSLGKRISFIRNAIRELRLTNVTPVLSRVEEYQ-PEDKFDGVLSRA----FASLKDMTDWCHHLPKENGYFYAL............................................................................................ 145
41 -18.900PF02475.16; O28306_ARCFU/90-284; Met-10+ like-protein  ali follow..  22  98..DGEVVVDMFAGIGYFSIPIAVHSKARRIYSIEINPESYKLLLENIKLNDVGNIVPILGDSQFV-TPEGVADRV-----VMGHIYCHDYLHTAIRALKERGVV............................................................................................... 193
42 -18.700PF08123.13; DOT1_DEBHA/959-1163; Histone methylation protein DOT1  ali follow..  20  41.QPQHKFYDLGSGVGNTTFQAALEFGVHLSGGCEIMEHASKLTELQTMLLNALSQSFVENDIVRQAVIEC--DVLLVNNYL-FDVNLNTAVGKMLYGLKPGTKIISL............................................................................................ 158
43 -18.400PF05185.16; ANM5_ORYSJ/308-478; PRMT5 arginine-N-methyltransferase  ali follow..  16  62.TTKTVLMVVGAGRGPLVRASLQAAEETKVYAVEKNPNAVITLHSLIKLEGWESVTIISSDMRCWEAPE-KADILVSELLGSFGDNELECLDGAQRFLKPDGISI.............................................................................................. 171
44 -18.000PF01739.18; CHER1_PSEAE/72-269; CheR methyltransferase, SAM binding domain  ali follow..  23  33.....RIWSAACSSGQEPYSLSMAIDEFQIVATDLSGSMLTAAKAAVKPAIRSRVEFRALNLLDSYASLGKFDMVFCRNVLIYFSAEVKILLRIHGTLKPGGYLFLG............................................................................................ 177
45 -17.300PF01596.17; A9PCU8_POPTR/22-233; O-methyltransferase  ali follow..  20  46.MNAKRTLEVGVFTGYSLLSTALALPDGQVTAIDKDREAYEIGLPFIQKAGVEEINFIQSEATPINDKQPEFDFAFVDA-----SSYKHYHEQLLKLVKIGGIIAY............................................................................................. 155
46 -17.200PF05958.11; TRMA_SHEON/10-365; tRNA (Uracil-5-)-methyltransferase  ali follow..  18  198QNSQGDLLELYCGNGNFSIALAQNFN--RVLATELAKPSVDAAQYNIEINGIDNLQIIRMSAEEFDLDSYLCNTIF-------VDPPRAGIDPLDLVQGYERILYIS............................................................................................ 313
47 -17.100PF01564.17; SPEE_SCHPO/71-256; Spermine/spermidine synthase domain  ali follow..  22  18..NPKKVLVIGGGDGGVLREVVKHECVEEAILCDIDEDVIKVSKQYLPEMS-PKVKVHIGDGFKLQDYQNTFDVIITD-----SSDPKPYFQLLSDALRGGGVITT............................................................................................. 130
48 -17.100PF00891.18; ASMT_BOVIN/117-327; O-methyltransferase domain  ali follow..  15  65....PLICDLGGGSGALAKACVSLYPGCRAIVFDI-PGVVQIAKRHFSASEDERISFHEGDFFKDALPEA--DLYILARVLHDWTDAKHLLQRVYRACRTGGGILVIESLLDTDGRGPLTTLLYSLNMLVQTE----GRERTPAEYRALLGPAGFR........................................... 211
49 -16.800PF10672.9; Q87QG2_VIBPA/25-310; S-adenosylmethionine-dependent methyltransferase  ali follow..  18  122.AKHKNVLNLFAYTCGFSVAAIAGGAD-KVVNVDMAKASLSKGRENHKLNGHNQVSFMGHDIFKS--KSGQYDLIIQKGSFALTKDYKKILRRLPDLLAEGGQVMACV........................................................................................... 238
50 -16.300PF10294.9; Q6C9L2_YARLI/34-201; Lysine methyltransferase  ali follow..  18  39.QSYPRVLEIGSGTGLTGLAIALSEPNLKVWVTDQ-ENMIPLMNQNIELNNLQDEVLDWGEELPEFLEGQPVDLVLAADCVYLESAFPLLEKTLIDLSNKDTKILMS............................................................................................ 150
51 -15.700PF04672.12; Q9WX26_STRCO/10-300; S-adenosyl methyltransferase  ali follow..  13  71....RQFLDIGTGAENVHQIAQRIAPESRVVYVDDDPVVLAHARALLTSGPEGRTDYIDADLKSLEQAAATLDFLCLVAILHFVEDAYPIVRELMDALPAGSRLVLS............................................................................................ 187
52 -15.200PF07279.11; Q9LZY5_ARATH/1-218; Protein of unknown function (DUF1442 topsan)  ali follow..  13  40.WNTRLIVETWSRGDPIATSVAAIHTCGRHVCIVPDEESRSEYEAVMRGAVTSDTEVMVLDSAEVVERISGVDFM----VVDSKRHEFVNALGLAKTSKMGAVLVC............................................................................................. 146
53 -15.100PF04989.12; A8ZT86_DESOH/39-259; Cephalosporin hydroxylase  ali follow..  16  30KVKPDLILETGIAHGGSLIFSASMNPIRRVLGIDIDIREHNRAAIEAHPMA-GRIQMIQGSSVDAEAKEFSRILVCLDS--HTHDHVLAELEAYAPLVSPGSYCMV............................................................................................. 160
54 -14.600PF06962.12; YTQB_BACSU/48-187; Putative rRNA methylase  ali follow..  13  1.............................VYAFDIQESAVANTKERLGDMYQARTTLFHKSHDKIPETHGKVAAAVFNSITTNGSSTIKAIEQLLSIMKDEGLIVLVVY.......................................................................................... 94
55 -14.200PF03602.15; RSMD_ECOLI/12-188; Conserved hypothetical protein 95  ali follow..  13  39VIVDAQCLDCFAGSGALGLEALSRYAA-GATLIEMDRAVSQQLIKNLATLKAGNARVVNSNAMSLAQKGTPHNIV--------FVDPEETINLLEDWLADEALIYV............................................................................................. 145
56 -13.400PF04816.12; Q9A050_STRP1/22-222; tRNA (adenine(22)-N(1))-methyltransferase  ali follow..  17  1......LLDVGSDHAYLPIFLVETNQISAAIAGEVVRGPYESALKNVTQSGLAEIQVRLANGLAAFEEADDVTAITICGIADILEAGKEKLQGIERVLQP................................................................................................... 101
57 -13.200PF04445.13; M4RGN1_BIBTR/17-246; Putative SAM-dependent methyltransferase  ali follow..  16  71..YLPTVIDATAGLGRDAFVLACIG--CKVTLIERNPIVSALLEDGLKRAYQERMVLAGVSAINLNIEQDFADVVYLDPMYPHKQKSALVKKEMRVFQH.................................................................................................... 175
58 -12.800PF00107.26; ADH_SULSO/182-311; Zinc-binding dehydrogenase  ali follow..  19  1............GLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGADYVINASMQDPLAEIRRITESKGVDAVI-------LNNSEKTLSVYPKALAKQGKYVM............................................................................................. 88
59 -12.800PF16912.5; I7BJ28_NATSJ/144-370; Glucose dehydrogenase C-terminus  ali follow..  16  30..QPASALVLGTGSGLLTAAMLTETLEYDRVYCLGRKDRPHPTIDIVDRLGATYIDSRETPVSEIPAAYEPMDLVY-------ATGYAKHAFEAIEALAPNGVAAL............................................................................................. 128
60 -12.500PF12847.7; A9KI22_LACP7/3-153; Methyltransferase domain  ali follow..  20  14..KGNVVADVGCDHAYISIYLVEGKIAPKTIALDVNEGPLLRAQENIISYGMENITTRLSDGLH-MLKPNEVDSIVIAGMIRILEEGSECVAAAKEILQP................................................................................................... 117
61 -12.100PF02005.16; TRM1_CAEEL/9-442; N2,N2-dimethylguanosine tRNA methyltransferase  ali follow..  17  80EDGKIRILDALSASGLRALRFSKEVPNGFIMANDFSDNAVASIQENVKLNGVEDVEAHFGDAVMTMMEDKRFHAV-----LDPYGTASTFLDSAVQCVADRGILMVT............................................................................................ 188
62 -11.300PF01728.19; Q7QB53_ANOGA/52-237; FtsJ-like methyltransferase  ali follow..  13  21..PGHTVIDCGASPGSWTQIAVKQKPKGMVVGVDLLQLRKETQDKIRASLGERRVDCVLSDMAPNASGIRALDQENITTLC------YAVLRFAILMSTPNASLLMKVWDNGDVPKLEKSIL............................................................................. 158
63 -11.200PF05575.11; Q56677_VIBCL/1-286; Vibrio cholerae RfbT protein  ali follow..  12  79..HDTTYIDIGANVGTFCGIAARHITQGKIIAIEPLTEMENSIRMNVQLNNPKNSQVLVRKLSSLDISPTNSVVI-----IDAEGAEIEILNQIYEFTEKHNGIEYYICFEFAMGHIQRS............................................................................... 236
64 -10.800PF12692.7; Q2K041_RHIEC/1-158; S-adenosyl-L-methionine methyltransferase  ali follow..  20  27DIEGP-VLEFGLGNGRTYDHLREKFPGRRIIAFDWEVRS-------YSASTPEPQDMVTGNIRDSAFLGIGAALAHADIGTGHDETLTWLPQLMAGVLAPNGIAVSGLPLEHPDLTALPLPEGIKE......................................................................... 150
65 -10.600PF05206.14; TRM13_KLULA/161-430; Methyltransferase TRM13  ali follow..  14  26..KTLEYIELGCGRAEFSRYVNIKAVAPSFTLIDRASQRLRFDNKFSSDIGTVQIRREKIDIKDLRLDAVLHDASQYVAISKHLCGVATDL-SLRCLLNSD.................................................................................................. 140
66 -10.600PF06460.12; R1AB_CVMA5/6879-7175; Coronavirus NSP16  ali follow..  10  62..ANMRVLHLGAGSDKGVAPGSAVPAGSILVDNDVSDSVASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYL------CHLIRDKLALGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEG.......................................................... 203
67 -10.200PF00398.20; RSMA_BACSU/19-283; Ribosomal RNA adenine dimethylase  ali follow..  15  29.TEKTGVIEIGPGIGALTEQLAKRA--KKVVAFEIDQRLLPILKDTLS--PYENVTVIHQDVLKADVKSANLPYYVTTPIIMKLLEEHLPLKGIVVMLQPSGSLSIAV........................................................................................... 160
68 -10.100PF05711.11; Q98ID4_RHILO/13-257; Macrocin-O-methyltransferase (TylF)  ali follow..  13  72GIVGD-FIETGVWRGGCCILMRGVIHDRKVYVADSLAVSLQTVKDNFSRYGLEQVVFVEGMFSDTSLSAGPFALLRLDGDLY--ESTIVALNSLYPKLSRGGVVIIDDRA......................................................................................... 212
69 -9.460PF05971.12; RLMF_ECOLI/3-296; RNA methyltransferase  ali follow..  17  99IPANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISSNPGLNRAIRLRRQKEIIHKNEQYDATLCNPPFHDSAAAARAGSERKELWCEGGEVTF............................................................................................. 230
70 -9.420PF14314.6; L_MOKV/1361-2051; Virus-capping methyltransferase  ali follow..  18  334DVCPCLSLVIGDGSGGISRVVLSMFPDSKLVFNSLPPSALMRGGDDITSRDFESIWEKPSDLRNQSKLRSQFDLIVCDAEVTDIESVNKLLSDFSMSIKGPLYLIFKTYGTMLVNPDYKAIHHLSR......................................................................... 488
71 -9.050PF01262.21; Q9S227_STRCO/141-353; Alanine dehydrogenase/PNT, C-terminal domain  ali follow..  15  25GVLAGRAVVIGGGSGWNAAQIAIG--GFHVTLLDKDITKLREADKIFGTK----IQTVVSNAFELEKACLEADLVIGAVLIPGAKAPKLVTNELVSRMKPGSVLV.............................................................................................. 125
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.