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Query: PF14631.6; U3I414_ANAPL/1-1417; Fanconi anaemia protein FancD2 nuclease, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MVSKRKLSKTDASGENSKPDLPSRCSETKKPRASDKEKASAQGGLESEGVFEELLRTSGIILKAGEGQNEIAVDQMAFQKKLRLTLEKHPTYPGVVKQFISGLESHIRDRNQFKNCLLPCAPVRTEGSRTLVHSYCESLIKMLLGINILQPAVITLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQQSEVARELGCLLKEGRRLTVPILDALSRLDLDAELLAEVQQSAMTIVPSVKLEDLPVVVKFILHNVKAANAVEVISDLRKNLDLSSCVLPLQIVGSQKKLKSQVQTSSSTSQVTTSQNCVKLLFDVIKLAVRFQKDVSEAWIKAIENTTSVSDHKKVLDLIVLLLIHSTNTKNRKQAEKVLRSKIRLGCMPEQLMQNAFQDHSMVIRDFFPSILVLAQTFLHAAHPAIVSFGSCMYKQAFAVFDSYCQQEVVSALVTHVCSGNEAELDIALDVLTDLVVVHTSLLMRYATFVKTILDSTQKLNPCQIRKLFYILSTLAFSQRQEGSYIQDDMHMVIRKWLSSTVPNHKQMGIIGAVTMIGSVALKRNEGDGGSSERPEPNFERDGQLSTLLDLVGFCCEQTPEVLALYYDELANLIEKQKGNLDLQLLEEFGKSLVEDFPTDFVVDLSPTVTGSFLFPVKPLYNLDEDESQGAIAINLLPLVSQSELGRVTDGTNNPSKRVVSPICLSPSFRLLRLYTGEQNNGSLEEIDALLGCPLYSTDLEVEGKIDSLSKQEREFLCSLLFYALNWFREVVNAFCQQQDAEMKGKVLTRIQNITELQNVLGKCLAATPGYVPPPATFDSEATEGGPSVNAVGAMRKKNGRKKKSDGSKASIADRSQADESSEGNQPDTELSELEKTAVEREAGNPLAQLQSYRPYFRELDLEVFTVLHCGLLTKSILDTEMHTEASEIVQLGPAELYFLLEDLCWKLEHVLTPGSTRRVPFLKERSYKDIGFTHLRQRSPKEVAVCVVKLLKPLCNHMENMHNYFQAVKQNQGVVDEPGVNIQEHQMMSSCYQQLLLTFRLLFAWNGFSQQENTDLLRSALQVVADRLKPGETEFLLLDELISESFQYLLNFQQSIPSFQCAFILTQLLIAISEKPMAGWKKEKMALLAKQFLCRSWVKPNGDQEKGSQFNSALHTLLCVYLEHTDNILKAIEEISSVGIPELINSAKDGCSSTYPTLSRQTFPVFFRVMIAQLESSVKSIPAGKPSDSSETQLEKLLQWNIAVRNFHILVNLVKVFDSRPVLNICLKYGRLFVEAFLKLAMPLLDHSFKKHRDDVQGLLKTLQLSTRQLHHMCGHSKIRQDLGLTNHVPLLKKSLEQFVYRVKAMLAFNHCQEAFWVGILKNRDLQGEEILSQASEASETRDSEEDLast
1 -312.000PF14631.6; U3I414_ANAPL/1-1417; Fanconi anaemia protein FancD2 nuclease  ali  100  1MVSKRKLSKTDASGENSKPDLPSRCSETKKPRASDKEKASAQGGLESEGVFEELLRTSGIILKAGEGQNEIAVDQMAFQKKLRLTLEKHPTYPGVVKQFISGLESHIRDRNQFKNCLLPCAPVRTEGSRTLVHSYCESLIKMLLGINILQPAVITLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQQSEVARELGCLLKEGRRLTVPILDALSRLDLDAELLAEVQQSAMTIVPSVKLEDLPVVVKFILHNVKAANAVEVISDLRKNLDLSSCVLPLQIVGSQKKLKSQVQTSSSTSQVTTSQNCVKLLFDVIKLAVRFQKDVSEAWIKAIENTTSVSDHKKVLDLIVLLLIHSTNTKNRKQAEKVLRSKIRLGCMPEQLMQNAFQDHSMVIRDFFPSILVLAQTFLHAAHPAIVSFGSCMYKQAFAVFDSYCQQEVVSALVTHVCSGNEAELDIALDVLTDLVVVHTSLLMRYATFVKTILDSTQKLNPCQIRKLFYILSTLAFSQRQEGSYIQDDMHMVIRKWLSSTVPNHKQMGIIGAVTMIGSVALKRNEGDGGSSERPEPNFERDGQLSTLLDLVGFCCEQTPEVLALYYDELANLIEKQKGNLDLQLLEEFGKSLVEDFPTDFVVDLSPTVTGSFLFPVKPLYNLDEDESQGAIAINLLPLVSQSELGRVTDGTNNPSKRVVSPICLSPSFRLLRLYTGEQNNGSLEEIDALLGCPLYSTDLEVEGKIDSLSKQEREFLCSLLFYALNWFREVVNAFCQQQDAEMKGKVLTRIQNITELQNVLGKCLAATPGYVPPPATFDSEATEGGPSVNAVGAMRKKNGRKKKSDGSKASIADRSQADESSEGNQPDTELSELEKTAVEREAGNPLAQLQSYRPYFRELDLEVFTVLHCGLLTKSILDTEMHTEASEIVQLGPAELYFLLEDLCWKLEHVLTPGSTRRVPFLKERSYKDIGFTHLRQRSPKEVAVCVVKLLKPLCNHMENMHNYFQAVKQNQGVVDEPGVNIQEHQMMSSCYQQLLLTFRLLFAWNGFSQQENTDLLRSALQVVADRLKPGETEFLLLDELISESFQYLLNFQQSIPSFQCAFILTQLLIAISEKPMAGWKKEKMALLAKQFLCRSWVKPNGDQEKGSQFNSALHTLLCVYLEHTDNILKAIEEISSVGIPELINSAKDGCSSTYPTLSRQTFPVFFRVMIAQLESSVKSIPAGKPSDSSETQLEKLLQWNIAVRNFHILVNLVKVFDSRPVLNICLKYGRLFVEAFLKLAMPLLDHSFKKHRDDVQGLLKTLQLSTRQLHHMCGHSKIRQDLGLTNHVPLLKKSLEQFVYRVKAMLAFNHCQEAFWVGILKNRDLQGEEILSQASEASETRDSEED 1417
2 -32.200PF14676.6; M3WHT5_FELCA/378-541; FANCI solenoid 2  ali follow..  12  1................................................................................................................................................................................................................................................................................................................................................................................................................................VTQGLVE-ILMDSYGPKKILDGKAIETSSCLSKKPTQHACKLGADILLETFKIHEMI-RQEILEQVFNRVVTRASSPISHFLDLLSNIIMYAPLVLQSCSAKVTETFDYLSFLPLQTVQGLLKAVQPLL----KVSMSVRDSLILVLRKAMFASQLDARKAAVAGFL.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 164
3 -18.000PF11894.8; C5DMA7_LACTC/4-1647; Nuclear pore complex scaffold, nucleoporins 186/192/205  ali follow..  403...............................................HHLLQVVITDCAFLLTK------MKDAEEDSLLSGEDLFLDEISAKADLERFFITVHYFYAFRPDYSAVF---------------QDKESNAYGFIWAMKCTDTLMRSCVFMMLSSLSFGPENSANV-------------HYVNLNANLSNTVSQLISDYIVKISELERKLLDGQQREEQDPTTIALKTGLNEEVIILLSSLYTLIGCVAHDLNEGAKAQLSILFEFVKVDTPLVGAALKVLSNLVPYD--ELERSKFWFNLDSWIFKGFRLTISDDSYREAFESILTHFQDITGFLQLLNSLLKVRTKSTNGYLEFGLQFPPKLGHGYRKLGIWPYFDYVFHGILAQSNKLPNPAER-----------------------------AIHKPILEILSSALSSFDYSVILNSIPSGSNLDELVVTDNFLTYAMTAVLNYLFEEN-----VFKNLLQNASFGVEKMGSITE---------DCQSLALPCLALSTINQVL----TIQETYVEELCPIVKKSASKNYFIPKDFGLHGLRSFYDAISFDLPLIVGIGLYVGHTNYKIASNSLDILDKISTEMKGRDSQAI---DKLLSVFDSVDE----------SARIKQAFINQLQTSIT-------------------NYESFSIKMRILDF-------------------------------ISKNLSYTDKQPTVAHF--LLGLQIGNTISLGPDLSTFVTSGC------------SVLTSIIYLLQSSLMVLSSEEIEFLPAKLASSSMEILLKLCKNSATSKIVLRHMSESDFFETILARDPKVDVNTRWSGEVFAGNSAGDSLGFIKQTSTGAFLSFLSYRS-----------------------------ALQYLSLDIHGLSGESLKSRIKSRIDLLISNYLQPPRLFSFLDALNFDARPSPHETLKGLKVLSGINFNLPSLQKVTPCT-CSELESLIRLRTQFLGKHLPLNFHEETITNKETLDRISGAEAATILSLLHSWVQLVQVVVLDGALPQVSISDFILRLFEAIVPKINDYVELDVCYSEELVSLCVFLYDLYQHTADGRLIALFLACINGIRSPLSTLALRSDFYILANRFLVSIMKEVNTAKQVLKTLKLTSERLVEVVCNDAISGEGSSRITGILFLDSLVQIAGLNKVNFVESLVKSNM---LLLISHSIKTTDDLLSSGLEGITLDNLLYELTAFKS------TIHFLIRIAESRSGAQALVENE--IFRVIESCEFLEADPDLGLETEVRTQESQAVRVTFSLDKSLNLSKDACGLSLFEIIVPVFQ-----LMTSILISMGSANKPVLKKTRNLHFRKLVQGVLKRDALIEGSDEKHLDR 1624
4 -14.900PF14675.6; Q7Q1S0_ANOGA/59-282; FANCI solenoid 1  ali follow..  15...............................................................................................................................................LNVVELSTKQVFDLIARLLTDLPSLTPEQLVEICELCIESIR------AGDPKCLTWKHLLPQTLLQLNAGRLNANGMLLTGAEYRQKVLEEIFKMKLQLAILTALCGMFRDLTLSKDETSIFVTKVSDSLKNIEPLELPPLACQLFHVCLKHPSLLPLMALQKYFH----KNYYKKVLSNENSDTTDFDSIDRYSDSEIREAEETILFHLSNVTE.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 224
5 -14.100PF11573.8; J9K0B7_ACYPI/12-1339; Mediator complex subunit 23  ali follow..  1...................................................................................................LNQILNEIAKVDELVEAFNGYIQKDSLNNCEQIEKLFMMLTNIV---IRLNDEQLSMSIKIILKTASTQTVSVRQKVFLNMLQKL---KHGVSSRLMCECIIEYLVHTNSEFWIECFHIIKSILDTVDYKGV-----------REILKGCFDKVVAMALPASILPQFLAEVIRYIFDRESCLLPGVINEILKVYSENKGGCLVSNFVESFRGAAQMTSMIGHSSMLPVVEHSGYADHLITPWKLDPNTLKL--TLKGNIPYPKQLLQPQTKLLRYVLEQPYSR---DMVCSMLGLQKMNKQRCIVLEEQLVELIIRSMEKSDKEVTEGADPEENHWLWLHISSQLIYFILFQFAVFPNVVNALHEKLLKKDLHRSRDRLMWVLLQYISGSIQKNILPVLKLYDLLYPEKTCIWIHLLRKALMDNIKFHRPIPLALKAHHEYLQMLVQPSNSALCMGTDYRVPLLCNAFSTNNECLSRP-MAALVDAVLGSSSNRGISGSGGTTSPISGNASSSNAMAVLDSL--TIHAKMSLIHSIVTHVLKLAQSKSNLAAPALAETYSRLLV----------YTEIESLGIKGFISQVLPTVFKSHAWGILYTLLEMFQLLSHLHSLAAVPQTNQTQLHLCVESTALRLITGLGSNEVQPQLEELNRALVLTLA------SMHITGTSASQEGSWCKELLTTITWAPHTLQCFPPALADFFVHNPITK-ENKQQLKKAVEEEYRNWASMTNENDIIAHFSVPTAHPL-----KMIIETDRINPIAYKILERIGARALSAHLRKFCDYLVFKFAVSEEGQHVNKCVDAINSMIWKYNTIDRLVLCLA-------------LRTQEGSEAQVCFFIIQLLLAEFRARVCEFVKENSPEKHLAFHRKYPEKFAPEGILDPASYQPLNVCLRFLPVFDIVIHRYLEL-------PPVTKSLETLLDHLGCLYKFHDRPVTYLYNTLHYYESKLRDRPSLKRKLVYAVLGSLCETRGCWTLSESYQRYNIQ--TPTSTISNSMGTSTDVTVTPSAPIWVPDLEYYVMLVKRITDTM-NIDWRFNEFPNPAVYALYMTCAELMALPLTPAS--ANSLLDVVMQRYTEIPSHEIHCWINSIGLIMSAMPEPFWVTLQDRIMQMMQSPGLATWHYAHNFDLAHGCMLDNRFIYMLALAHATWHHAGVGHIASIPL---------------FVKEKLGPSVYSEEQFIFLCHLVAPFLSRYNLDKPSPSIVDVTVELFNALERMDKLLYHIKYQYV....................................... 1327
6 -12.900PF04931.13; K2SXE2_MACPH/89-879; DNA polymerase phi  ali follow..  11  1..................................................................................................................KAIVRLIRGLNSGRKAARFGFFVALTETLRQLYGSSSKEIHGLVKLVAELTTPEGKASGQEKRDYLLGRVFGYKAIIQSSILVQ------PNAPEECWANVLEQLFKLAREKPW---------LREECGMILCEAVKAIAQEKGQQRLVKQIVDGLCSDGLAKTPEGVSVWITV----------------------------------QREIPDMELPQGVWHKEDPLSTKDRQTLANVMKENFTKTSDGANETGKKVKGSSQTTALSFSWDVVISAFFQRHGDDPSRFANFW-----------ADIVDNNLFSASSSPEQKSKGLQLFTRMLGNAPKWALPSFSPNLMRCLINQRNDSERHNAAKAPLDEMRTRSKKEPETAAPFLENLITKHGSLHFDQITKNKTVEGVLGHANDVALEQIVPLFKRLIYRPEEQDSKVADMVVSAVRSRNKENAIGNDLREVLVGLTELAYFTPTASSSPDDLPLPAVSEASRNMFQGRLTSCLAHLLSSKLDTEMDYPYIVVSAIRSSKSSKSLSLVFQADKGISKAVKQ----------------------------------------AHKQVEEITEKLLKAKDKKKPALRAFKLLFSLTIVQVYNGDPDAVSILEELAVCYESAFQKGADKSAFQL-----EVLLSFAAKPSVLFRKLSEQVFTVFASELTAEGLHSMIDILSKKESMSGQQDLFDQQGSEDGEDASEDDEDEQDSDVEMVEADGSDVEEVEEASDVDEEEEEDEDEEGGEDGSDADDEELEKLTGEGEDSDDDDEADMDDDQMMALEPHLTKIFKQRQEAANKSKKKDNKDAKATMINFKNRVLDLLL.............................................................................................................................................................................................................................................................................................................................................................................................................................................................. 788
7 -12.100PF16206.5; B4H8S9_DROPE/917-1701; C-terminal region of Mon2 protein  ali follow..  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DFLTVMPWRCLPLCISTAAKFGSQTQELNISLTAGLMWNISDFFNQNQDKLMS-------------TQLQDVAILPEFPGTVKMPQFDKLWMCLYAKLGECVDLRPAVRKSAGQTLFSTISAHGSLLNPPTWQALVWQVLFPLLDNVRALSSSASNEKVDASGNILIHHSRNTAQKQ--------------------------AETQVLTLSGVCRVFNT---------------------KRELLQMLGDFERA-----------------WILEFIQNAALSKNGEVSLAALKSLQEIMYHNTTTERTVGGVGGASLKDPQTAQEQDEEIWTYLKSIEKQFSTFRVNHMELFFIAWNIWLSIGMESTKMSTTKAQPQPSSNGGSNGSQDSQEDFYIPSQAFLTALIQIFPAI-----------------HHIQVKFSPTDFDKFCTVLTNAVCIPVQTDAVPYI-------------STVSDTLLTPLHDGILDCMELIQKEATKPDSHISQL-------------------IPAIFRQLLIFSKFACAPPTFQQNVEHKYAKSTSGHYANNASVEVVGMNPFGEKSISICVKLYQTTATEESVVQEQILHDIVKAVRTKCLSSSTWKLAISSLISVLHTGLKVARAKPQHFASLWDDLADTLDKFLLDETIDCHVIELLRDEVLPHAHEMPHQFIMQIVVLLNKGSIEIFAKTCFETLLQ-FSLLEDHHATNNNRINANLLPAGAAGAVGKDFAGRLA--------VTALLHRFQEVLKRFNDD-CPL-----RFRLSEISFVLKAIATLVVSMKKA-SKVNKPAWDQLIGLYPEVSRSLREALLQYTDLLQ....................................... 783
8 -11.500PF05804.12; KIFA3_HUMAN/13-720; Kinesin-associated protein (KAP)  ali follow..  68LIHPSKLNEVEQQNRRDSLSGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIE----LLYEDIPDKVRGSALILQLARNPDNLEELLLNETALGALARVLREDWKQSVELATNIIYIFFCFSSFSQFHGLITHYKIGALCMNIIDHELKRHELWQEELSKKKKAVDEDPENQTLRKDYEKTF-------------KKYQGLVVKQEQLLRVALYLLLNLAEDTRTELKMRNLVKALDRNFELLILVVSFLKKLSIFMENKNDMVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNKMVQVGLLPKLTALLGNDNYKQIAMCVLYHISMDDRFKSMFAYTDCIPQLMKMLFEC---DERIDLELISFCINLAANKRNVQLI---LKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFID--------------YVGDLAAQISNDEEEEFVIECLGTLANL-DWELVLKEYKLVPYLKDKLKPGAAEDVLEVVIMIGTVSMDDSAALLAKSGIIPALIELLNA-DDEFVCQIIYVFYQMVFHQATRDVIIKETAPAYLIDLMHDKNNEIRKV----CDNTLDIIAEYDEEWAKKIQSEK------RWHNSQWLEMVESRQMDE..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 682
9 -11.200PF09735.9; E2C9I5_HARSA/8-1117; Membrane-associated apoptosis protein  ali follow..  1..................................................................................................................................................................................................................................SQQKLAEKLTILNDRGIGMLTRIYNIKKACGLSDKALESSIKAIVRKFPNIDIKGLQTI---------TNIRNEIIKSLSLYYYTFVLDFKDNVCELLTTMDACGVHMDITINFDLTKGYLDLVVTYISLMVLLSRVEDRKAV-----------------LGLFNAAHEMVHSQSDPSFPRLGQMIMDYDAPLKKLSEEFVPHSKLLKNALISLWPIYPSLVGSPGQILKAAATETMSCETLSLDRIERWVILGFTLCHTFLSQEQPNKLWITALESLFRDEVIYIHQYIQTFFESMKGYSKRV----SEVKECYNQAVQKAGYRHRERRKFLRTALKELGLILTDQPGLLGVLMGLSHARDLRHGDNPPTQGKGKGRGGEDLVDRQLPELLFHC---------------EELRALVKKYSQVLQRYYVQFLAGFDAPALHQMILPVCPEDEGAILSDMCSTIASLTVKQVEENELFDFRAFRLDWFRLQAYMSIAKGNMNLADNRELASFMDTV-IFHTKMVDNLDEMLVETSDLSIFCFYSKIFEDQMCLEFPAQNRYIVAFPLICSHFQSCTHELCPEERHHIRERSLSVVNMFLDMAKEAKNIITTICD--------EQCNMSDKLLPKHCALLISQVVNRKKKDKNKKNMYEIHKPGIESFRKTREELTTMDKLHMALTELCYAINYCPTINVWEYTFAPREYLHQHLESRFARALVGMVMYNPDTSEIAKPSELFVSVRSYMNVLQTIENYVHIDITRVFNNALLQQTQELDSHGDKTALYTQWYSDVLLRRVSAGNICYSANQRAFVSLSVEGAIPFNAEEFSDINE-----LRALAELIGPYGMKM-----LNENLMWHIASQVQQLKKLVTGNRDVLVALRTNFDKPEVMKEQFKRLQHVDNVLQRVTIIGVILSFRQLAQSALVDVLEER---------------PFLLSSILDFRHHSGDPMRVVSEMTSAALTCKVDPTLTTALRNQKGEPEEDEHLLVCLLMVFVAVSIPKLARNESSFYRASLEGHSNNIHCMATAINNIFGALFTICGQNDIEDRMK---EFLALASSSLLRLGQEADKEATRNRESVY--------LLDQIVQESPFLTMDLLESCFPALIRNAYHDVYKL............................................ 1110
10 -10.900PF14228.6; F6GVU1_VITVI/618-1735; Cell morphogenesis central region  ali follow..  9......................................................IDAVGLIFLSSVDSQITALELLRCVRALRNDIRDSLYERFDNNLKNDAIIDVLEENGDDIVQSCYWDSGRPFDMRRESDAIPPDATFQSILFESPDKNRWARCLSELVRYAAELCPSSVQEAKLEVIQRLAHITPAELGKDLYHLIFPSLKSGSEAHIHAATMALGHS-------------------HLEVCEIMFGELASF---DEVSMETEGKPKWKSQKARREELRVHIANIYRTVSELHYLKFIEETTRQILTAPSENFQEIQPLRYALASVLRSLAPEFVDSKSEKFDLRTRKRL--------DLLLSWCDDTGSTWVQDGVSDYRREVERYKSSQHSRSKDSVDKLSFDKEVSEQ--VEAIQWASMNAMASLL----GRVISWINSLFNEPAPRAPFGYSPADPRTPS-YSKYTGEGPRGAAGRDRHRGGHLRVSLAKMALKNLLLTNLD-------LFPACIDQCYYSDAAIADGYFSVLAEVYMRQEIPKCEIQRLLSLILYK-VVDPNRQIRDDALQMLETLSVREWAEDGGEGSGSYRAAVVGNLPDSYQQFQYKLSCKLAKDHPELSQLLCEEIMQRQLDAVDIIAQHQ---VLTCMAPWIENLNFWKLKD------------------SGWSERLLKSLYYVTWRHGDQFPDE--------------IEKLWSTIAS----------RNISPVLDFLITK-------GIEDCDSNASAEISGAFATYFSVAKRVSLYLARICPQRTIDHLVYQLAQRMLEESVEPLRPSANKGDTSGNFVLEFSQGPVAAQIASVVDSQPHMSVRGSLDGPLRNASGSLSWRTAAVQGRSVSGPLSPMPPEMNIVPVTAGRSGQLIPALVNMSGPLMGVRSSTGSLRSRHVSRDSGDYVIDTPNSGEEGLHGGVGMHGVNAKELQSALQGHQLHSLTQADIALILLAEIAYENDEDFREHLPLLFHVTFVSMDSSEDIVLE----------------------HCQHLLVNLLYSLAG-VENSDGENKQQVVSLIKYVQSKRGCMENEDPTVVRTDLPSAALLSALVQSMVDA---------------IFFQGDLRETWGAEA------KWAMECTSRH--ACRSHQIYRALRPSVTS-----DTCVSLLRCLHRCLGNPVPA...................................................................................................................................................................................................... 1115
11 -10.500PF14750.6; D2A4V3_TRICA/20-1066; Integrator complex subunit 2  ali follow..  10  1..........................................................................................................................................................................................................................................MHQLSECTEVEIRPVLPCLVRMGLTSKKCTTMKVDILTIVSGMELVNS-------IVALLSIDFHRLETEVKKEQQLRQKGVALQNDSILIGNLSNTSMALEYERSDMTRRLSILLGELLYVQSQIQDENSDT--SYIKPSELFDNDIFAEELSDIICIALAELPITLNILTITETLLHLHN--PPIICRIVANFPDCFREVCTYLIQTGEKQEETKLSTVRAATISLLCKMNPSQALTIRSKCVELAITLSLDGGEGDMVAFISGL--LLGNDQTIRNWIALFIRTGQKKKGEISSTALLQL--------------REELLRRLHVILAASVEGHLLDSLVVQGSALLRLYCALRGIAAIK-------------QEDEVTALVRLLTSHPSPTPAGVRFVSIGLCMLIACPSLISLQEHERRSIEWVQWLVKEEAYFESASGVTASF----------------GEMLLLMAIHFHSNQLSA-----------------ICDLVCATLGMKIPIRHNNMTRMKQVF-TQEIFTEQVVTAHAVKVPVTNSLSANMTGFLPIHCIHQLLRAF-AKHNVNIKNWIYKQICTSSPLHPVLPMLVEVYVNSVIMPTSRNTETNKPLSENEIRRVFQSSIFGQYFDHKKSIFTMDFDLNSENQDVVVDGTSLTPQ-----EDCRLVNAHILAAFNRKIKLYSSEFLSELPIKYLLHH-------------AQKDQSSYSGLFGPLLKLLATHFPHLTLVEDWLDDMSIKTEHKPTHVTQISVIEAFNDLDTNPSKCAKLMQTLLKQAIDIWPFAEIFTQFARKILNDNVPRYLQDLYRDVWLRFNT-----------VLPRRLWVLTVKNLVDDFSNLTRIDVAEDPLQIMRCDERVFRCAPLYAIVLRVLRASLASSRSQLMQHLQANPRLDHAGQVLNESDREEMCRATISAAVQMLLETCIETDEDRLQEVRSLVCSYLHQVFIADTM-------LAKLVHFQGYPSELIEVMVKGVPSMHICLDFLQELMQQPSLDKQIFAIQLLSHLCIQYALPKSLNLCVAALNLLYALLGSLSS----------SQRVRLFRPILPAL-------------------VRISEAFPPLVDDIVNLMMQLAKVCKSQ..................................... 1045
12 -10.500PF10508.9; A7SP09_NEMVE/2-505; Proteasome non-ATPase 26S subunit  ali follow..  10  5..............................................................................CKELVENISN--ASGDEIVAFLRDLSVLISSSPNIRDLASLIPS--------------ERLFNCLRTTNTDQITYCKNILKNILKFEKPDANHPTEDVRELCLIELERC-ALMDKEDLLSYIARGMADEHLKNAQIASNVFTNLAKHEADSHLQSEFNALLKTKDTVRMRVYDMYITVQAHSPKAFDIFEKLISELDGRDVLVQMNCLELLTKLASISPQKGVVTKLNNLLLEVETDLITLIIPGIIKFFGTLATAHPLETTQQYPQFLEQTYSMISCG---DPTLMPIAMETIGVIAHSEDGLRAV--------------------------FNNQGRNKHIMKTIFGHATSSQVDLRKRALEALASIFYSEQLTPSEELCEFAKVLYKNMA----AAPLEAIFTVAKQPFEELRCSALCLLRSLARYQLQDMINCPGFLEYLLDRRTEFEKSGKEHKYDLIKELV-HFPPAKQIFDRPYFLRLQEYEREGPFFARAEAAVAF................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 500
13 -10.100PF05918.11; D7TJH2_VITVI/11-547; Apoptosis inhibitory protein 5 (API5)  ali follow..  11  1.........................................................................................................................................................IEKLYEYGERLNEAKDKSQNVEDYRGIIAAAK-----IKAKQLAAQLIPRFFKFFPDLSDAAVDSHLDLCEEEERVQAIRGLPLFCKDTPEYVSKIVDILAQL--ENVERDAVHKALLSLLRQDVKASLTGLFKHIMTVDDPSTDENLREKVLNFIRDKVFPLKAELLKPQEQMERHITNLIKKSLEDVTGAEFKMFMDFLRSLTLFGPERVQELIEIIEGQADLDAQFNVSDGDHIDRLISC-----YMALPFFVRGASNSKFLNYLNKHIIPVFDKLPEERKLDLLKLAESSPYSAPQDSRQILPSVVQLLKKYMPRRKTGECLLYTFHHLAYKAPNATNSLCGYKIVTGQPSDRLGEDFSEYYKDFTERLTHVEELARATMKKLTQGMAEHNKAMAAAKSDEAKDNIKTQKQNTTTGLRTCNNILAMT................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 442
14 -9.830PF11277.8; E2AUW9_CAMFO/78-1048; Mediator complex subunit 24 N-terminal  ali follow..  25........................................................................................................................................................................................................................................................................................................................................................................................................................................................INIKTILPRGVSGDVHNLADCILQQALVGPGP---NQLVLSYLKHSLSSQLVSYAAVLQRISKYDAHKPHCILSLLEFLESIQVGITCRGKPEEDLLAAAVLSIVH--------LLQCYLHALTKTPQNNSLIPNSNELDKPASILQQML-------------------NSDFMCAMMYLAKYDDKDLYIDVAKKCQEIERFLKTSNQKSAVPIEDSLKKLCNLEIESLSFEKIRMESITHCLQPLFAVQVLLNPSTETAVFVNQLLMVQRLKSYTNERLYCE---------IIRACLMCLHNVTGTFKESQWGAF-TFLKVPLILKELHAATLNSDEKFEYSQDILDAFELLLQ-FTPLLDIMDSTCSCNYVECLLNELQKVNLVTEKQAKQIS----------------ARREGVTAALQKLEPSNTPTSSIPKVIIRAKPTLAGILKTLNADYTKIQEALLSMLYHVLTGNSFELMLAVATVEGKLKTFVAKLIKFNESSKQINEPVPDKTAATRAML--DVSFLMLCSIVQTYGSDVVLEEGGDSFFEQERNKPKSPQKMLQSVDPARVDALLAQIAMGAVKEL---------CAWESGVLGAGDVKRALDGLRTAACCLPVCAAAWLCAYMSITHQDALLKPMNMVQHFLTPLPGDE-MQDNLKERSSLMFQIIRKMQYDVHPPTQSKT--KVLSMSHSIISRQPILEQLESVWQNINQRGWINIQATQSLESLLNTGVTNIVKEVLKYRYDIENCTLDLINHIIPQYLHNSLQNDELVEPILAKLCVYCIFSTLEYINSNPYRGNNRKRVRRELDADELDPLSMSNKLLRLNETGESIPMYGSQSPQVQSTSNGQKSEIILKDPLMTALNNLFTIFSFLAGRISQQTHFIFQFLRLTVQ-CGKDRTRIVLQGMP--QTLVPCLLKALPELFTTDILLRLYDIQTIIGRKATARDL................ 970
15 -9.380PF03635.17; M4CD11_BRARP/13-749; Vacuolar protein sorting-associated protein 35  ali follow..  3.....................AAGAAAFKQNAFYMQRAIDSNNLKDALKYSAQMLSELRTSKLSPHKYYDLYMRAFDELRKLEIFFMEETRRGCSVIELYELVQHAGNILPRLYLLCTAGSVYIKTKEA----PAKEILKDLVEMCRGIQHPLRGLLAQISRDKLPDIGSEYEGDADTVTDAVEFVLLNFTEMNKLWVRMQHQGPARDKEKREKERSELRDLVGKNLHVLSQLEGVDLDMYRDTVLPRVLEQIVNCR-DEIAQYYLMDCIIQVFPEYHLQTLDVLLGACPQLQPSVDIMTVLSRLMERLSSYAALNTEVLPYFL------------------------------------QVEAFSKLNNAIGKVIEAQEDMPILSAVTLYFTLHVHPDRLDYADQVLG----------SCIKQLSGKGKIHDTRATKELVTLLSAPLEKYNDVVIALKLTNYPLVLDYLDSENKRVMATVIIRSIMKATAEKVEALLELIKGLINDLDEPQG-------------LEVDEDDFEEEQNSVARLIHMLYSDDPEEMFKIISVLKNHFLTGGPKRLKFTIPPLVVSALKLIRRLPEEGDNPFGKE--ASVSATKIFQFLNQIIEALPSAPSPDLAFRLYLQCAEAANKCDEEPIAYEFFTQAYI--YEEEISDSKAQVTALQLIIGTLQRMHVFGVENRDTLTHKATGYSAKL-------------KKPDQCRAVYACSHLFWLQDQETIQDGERVLRCL---ALKIANSAQQMTSAARGSTGS----------VTLFIEILN-FYEKGIPQVTVESVESMIQLIKNE.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 737

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Godzik A. Fold recognition methods. Methods Biochem Anal. 2003;44:525-46. Review.