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Query: PF15818.5; G3T452_LOXAF/26-1066; Coiled-coil domain-containing protein 73 family, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst QLLDFKTSLLEALEELRMRREAETQYEEHIGKIIVETQELKWQKETLQNQKETLAKQHEEAMAVFKKQLQMKMCALEEEKGKYQLATEIKEKEIEGLKETLKALQVSKYSLQKKLSEMEQKVQLHFLAKEDHHKQLNEIEKYYAIITGQFGLVKENHEKLERNVQEAIQLNKRLSALNKKQEFELCSLKKELKKVTSDLIKSKVTCQYKMGEENTNLTIKERKFQELQERLNMELELNKKINEEISRIQEEKQNVIISFQHMQQLLQQQTQANAEMKAELKVLKENNQTLERDNELQREKVRENEEKFLNLQNEHEEAQGTWKKHVEELNGEINEIKNELSSLKETHIKLQEHYNKIYDQKKFEEDKKFQNVPEVSNEHSRMSAEKSEDTTILTYNSGQEIREENSMNFCSDTEYREKKEGPPKEEIIIEDLQLLEKSCKNEIITTVPQDENQSEISLSKVLCTDKEVISQGQTLNVPDFRKSITTEIKDKLCLEKDNGCTEFQSPTSLILVADTSIETKMIHLESMGGLDSHHPDVHLEAENHRSCDSILNDNTNHSKDVSENEPFKQQFRLLPCTQKSTAERVMTNTDQTKAELDSSLDVKEKPVHWEKCSLHNSSSVMLDDKRCKTKQLLRTQSECGILPLKQTSDFQQLCNDTSEKAQLNIPCDTASSYPISYAAFSDNLKLLENSDKKVSIVPMLVKPNSSPGKRTTRKNLDAQSSQFKDCLERLENNMTIPHLQIDNENIHASQPKDMKTAVYRKTSTEIQLSSKDSQIDENQITEATKNDLFLLVNVNERQHSLLNNTEKTESLNDIVSEKIYIEGQLEESRSFHIKASGDSVNTSGMSAFDLSTSDKKTEKTPVYLNFLDPGTWSKVNQIESQTVSTSASSILSSPKERPIGPSENKKIVSTTLGKNTGVDEVRKGVVRPDTTSINRVADTLNNSSIHPDPKGEPSEERNATAKTFYDSSFPTEHVKTKPLKSTLPRSPFQATEIKDTTDLAASFTAEDDWQSLVTKQINEIEKLLSLESDNRPRKRKAEEMLLast
1 -142.000PF15818.5; G3T452_LOXAF/26-1066; Coiled-coil domain-containing protein 73 family  ali  100  1QLLDFKTSLLEALEELRMRREAETQYEEHIGKIIVETQELKWQKETLQNQKETLAKQHEEAMAVFKKQLQMKMCALEEEKGKYQLATEIKEKEIEGLKETLKALQVSKYSLQKKLSEMEQKVQLHFLAKEDHHKQLNEIEKYYAIITGQFGLVKENHEKLERNVQEAIQLNKRLSALNKKQEFELCSLKKELKKVTSDLIKSKVTCQYKMGEENTNLTIKERKFQELQERLNMELELNKKINEEISRIQEEKQNVIISFQHMQQLLQQQTQANAEMKAELKVLKENNQTLERDNELQREKVRENEEKFLNLQNEHEEAQGTWKKHVEELNGEINEIKNELSSLKETHIKLQEHYNKIYDQKKFEEDKKFQNVPEVSNEHSRMSAEKSEDTTILTYNSGQEIREENSMNFCSDTEYREKKEGPPKEEIIIEDLQLLEKSCKNEIITTVPQDENQSEISLSKVLCTDKEVISQGQTLNVPDFRKSITTEIKDKLCLEKDNGCTEFQSPTSLILVADTSIETKMIHLESMGGLDSHHPDVHLEAENHRSCDSILNDNTNHSKDVSENEPFKQQFRLLPCTQKSTAERVMTNTDQTKAELDSSLDVKEKPVHWEKCSLHNSSSVMLDDKRCKTKQLLRTQSECGILPLKQTSDFQQLCNDTSEKAQLNIPCDTASSYPISYAAFSDNLKLLENSDKKVSIVPMLVKPNSSPGKRTTRKNLDAQSSQFKDCLERLENNMTIPHLQIDNENIHASQPKDMKTAVYRKTSTEIQLSSKDSQIDENQITEATKNDLFLLVNVNERQHSLLNNTEKTESLNDIVSEKIYIEGQLEESRSFHIKASGDSVNTSGMSAFDLSTSDKKTEKTPVYLNFLDPGTWSKVNQIESQTVSTSASSILSSPKERPIGPSENKKIVSTTLGKNTGVDEVRKGVVRPDTTSINRVADTLNNSSIHPDPKGEPSEERNATAKTFYDSSFPTEHVKTKPLKSTLPRSPFQATEIKDTTDLAASFTAEDDWQSLVTKQINEIEKLLSLESDNRPRKRKAEEML 1041
2 -10.300PF15921.5; G5BJQ7_HETGA/1-1111; Coiled-coil domain-containing protein 158  ali follow..  15  519EITKLRSRVDLKLQELQHLKTEEEHLQEALRLQMAGKDKVIEILRQQIENMMQLVGQHGRTAGAILVEKAQLEKEINDRRLELQVLKDKKDAKIRELEAKVSDLELEKVKLVNAGSERLRAVRDIKQERDQLLNEVKNSRSELNNLSEDYEVLKRNFRNKSEEMETTTKLKMQLKSAQSELEQTRNTLKS-MEGADGHAVKVAVGMQKQ-------ITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTV---------------------ATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAE-----QDIIQRQEQESVRLKLQHT..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 843
3 -9.830PF05911.11; W1PWE2_AMBTC/32-946; Filament-like plant protein, long coiled-coil  ali follow..  14  1.....KDDIVK--QHSKVAEEAIAGWE----KAEAEAASFKQELDGVVRQKVAAEERIVQLDAALKECTR-QLRHVREE----------QEERIDAIMKTTRDMDKVRIEIEEKLSETSKRL-IQVTADNNQLHK---------ALQVQEKLIEEISERKSQAEADFNALLSRLDSAEKDNS----ALKYEVCMLEKEL---EIRNEEREYNLKSSEASRKQHLESMKKIAKLEMEVRKRLPAALAQMKNEVENLGRDAFDQRKKKWNASHGSALIVRDYSLSDDAQEAANKRISILTERLWEMEEETKILKETLTKKNSELQSSRTMCARTVSKLSQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 309
4 -8.920PF06070.11; PP150_HCMVM/1-1048; Herpesvirus large structural phosphoprotein UL32  ali follow..  9  3..LQFVVALVNFLRHLTQKPDVDLEAHPKINELML--RELRFHNPDL----SSVLEEFEVRCAAVARRGYDHLAVLDRTEAKMSV-VHLKDTEVQRIEENLEGFCAKPLDLNLDRHANTA---VNAVNKLVYTGRL-NVRRSWEELERKCLLVKELRMCLKHAVENGDSADTLLELLIED----FDIYVDSFPQSAHTFLGARSPSLEFDDDANLLSLGGGSAFSSVPKKHVPTQPLDG----------------IASPWKGHKPFRFEAHGSLAPAAEAHAARSAAVGYYDEEEKRRERQKRVDDEVVQREKQQLKA---WEERQQNLQQRQQQPPPPTRKPGASRRLFGSSADEDDDDDDDDEKNIFTPIKKPGTSGKGAASGGGVSSIFSGLLSSGSQKPTSGPLNIPQQQQRHAAFSLVSPQVTKASPGRVRRDSAWDVRPLTETRGDLFSGDEDSDSSDGYPPNRQDPRFTDTLVDITDTETSAKPPVTTAYKFEQPTLTFGAGVNVPAGAGAAILTPTPVNPSTAPAPAPTPTFAGTQTPVNGNSPWAPTAPLPGDMNPANWPRERAWALKNPHLAYNPFRMPTTSTASQNTVSTTPRRPSTPRAAVTQTASRDAADEVWALRDQTAESPVEDSEEEDDDSSDTGSVVSLGHTTPSSDYNNDVISPPSQTPEQSTPSRIRKAKLSSPMTTTSTSQKPVLGKRVATPHASARAQTVTSTPVQGRLEKQVSGTPSTVPATLLQPQPASSKTTSSRNVTSGAGTSSASSARQPSASASVLSPTEDDVVSPATSPLSMLSSASPSPAKSAPPSPVKGRGSRVGVPSLKPTLGGKAVVGRPPSVPV---RLSGSSRAASTTPTYPAVTTVYPPSSTAKSSVSNAPPVASPSILKPGASAALQSRRSTGIAAVGSPVKSTTGMKTVAFDLSSPQKSGTGPQPGSAGMGGAKTPSDAVQNILQKIEKIK-NTE..................................................................... 1048
5 -8.460PF15254.6; G1T8F1_RABIT/39-892; Coiled-coil domain-containing protein 14  ali follow..  19  335TTIKY------FLGELK----VAEQEDSEIQRLITE--------EACVSELPAVSGN-----TNIQVEIALAMQPLRSENAH--------------LRS--RQLRI----LNQRLREQEKT----------------KKTTGSVECNLELFSLQSLNMSLQSQLQESLKNQELLQSKNEELLKVIENQKDENKKYTSIF--------------------KEKDQTILENKQQFDIEITK--------IKIELEEALVDVKSSKFKLDTAEKENQILGITLR---------QRDAEVLRELTRTLQNSMAKLLSDLSVDSARCKSGNNLTKSLLNIYDRQLQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 584
6 -8.440PF05557.13; G3PW04_GASAC/52-714; Mitotic checkpoint protein  ali follow..  14  3EKVQSKNRYLQLDQEKR-HKRARYELERAASDSARDFEHEVDRNQDLLGRIKKLEERETEEAKNLRKNLDGLNRKVEERDTRLN-TISSLKDEIRELKQKIQNQDSAVSSHTLENQELQEHLDLQRRKYQEVSQLCQSLQAAQSSCSEHIITIKELERRLA-LQEQDFAIVKNI----KSEVARVPDLERDLKRLREDNAFLR--------ESRENCSLLKEEVEGLRKKLERTERTKEEMELEKERVAEKLRALSREVIHIQQIEISLKEQNYTLNSRVRSAERSQAELRAELSKQRGRTQEEQKKREAQDALVRRLQKR-TKERDGMRAILESYDGELAPAEYS....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 375
7 -8.380PF15070.6; W5MC41_LEPOC/402-1036; Putative golgin subfamily A member 2-like protein 5  ali follow..  15  1.......QLMESVQQLKTERDQGKVWKDRTEQLLSQVNSLSEEKERSMTQIQELENL----VIELRNASALLSQEREDSENETALQEALGKQEKDDLSTQYQALSRLCQEQEERLLELERTVQRFSEDAVDRQQILESMQSDKATISRQNRELKEQLAELQNGFVKLTNENMELMSALQSEQHVKKELAKKMGQMQEELHQSREELEGKTQEARSLLEQRDQEREELHKQYLHQVQLMDRLQHEEVQGKVQLELSQKELERAKEKLTQLAKDNESLKTEVKELTGLGTQPRDQGDGVESKSPAESDSREEMAAFLQSALSQVEREWDEVSRLYEEEQR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 385
8 -8.370PF15964.5; SDCG8_HUMAN/6-706; Centrosomal colon cancer autoantigen protein family  ali follow..  14  302RLVKERDDLMSALVSVRSSQQREASAYEQVKQVLFEKKELERQAERLEKELASQQEKRAIEKDMMKKEITKEREYMSQNIAQLEAQVEKVTKEKISAINQLEEIQ-REMDVTKVCGEMRYQLNKTNMEKDEAEKEHREFDQEIEKLRIELDESKQHLEQEQQKAEECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEKTENEQYLLLTSQNTFLTKLKEECCTLRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQ------LERQSLSEEVDRLRTQL............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 700
9 -8.360PF02463.19; SMC_BACSU/2-1172; RecF/RecN/SMC N terminal domain  ali follow..  16  19..VDFKSNITDAIEQLRGGKMEDIIFAGSDSRKRLNLAEVT----TLDNDDHFLPIDFHE-VSVTRRVYRSRLKDIIDSQGKVEEILSSKAEDRRSIFEEAA---VLKYKTRKK--KAENKLF----ETQDNLNRVEELEGQVEPLKIQASIAKD-YLEKKKELEHV----EELHGKWSTLKEKVQMAKEEELAESSAISAKEAKIE----DTRDKIQALDESVDELQQVLLVTSEELEKLEGRKEVLKERKKNAVQNQEQLEEAIVQFQQKETVLKEELSKQEAVFETLQAEVKQLRAQVKEKQQALSLHNENVEEKIEQLKSDYFELLNSQASIRNELQLLDDQMSQSAVTLQRLADNNEKHLQERHDISARKAACETEFARIEQEIHSQV........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 451
10 -8.330PF05622.12; H2QW41_PANTR/12-710; HOOK protein  ali follow..  15  232RHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTLADEA-QSLKDEIDVLRHS-SDKVSKLEGQVESYKKKLE----DLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAAR----SQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCV--LTTQGLMPLGSQESSDSLAAEIVTPEIREKLRLQHE-NKMLKLNQEGSDNEKIALL------QSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQGAAPE............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 618
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.