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Query: PF00198.23; A4ICH2_LEIIN/226-463; 2-oxoacid dehydrogenases acyltransferase (catalytic domain), from PfamA32U

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst NPNFIDIPVTTMRSVIAKRLHQSKNLEIPHYYLFDDCRVDNMLALIKQLNAKGNGEYKITVNDYIVKAVARANILVPEVNSSWQGDFIRQYATVDVSVAVATPTGLITPIIRNAQAKGLVEISKETKALAKKARDGTLQPSEFQGGTCSVSNLGATGIPGFTAIINPPQAMILAVGSAKPRAEIVKSEETGEFEMTGRVENVVNFSASFDHRIVDGALGAKWFQHFHDAMENPLSLLLLast
1 -104.000d3maea_ c.43.1.0 (A:) automated matches {Listeria monocytogenes [TaxId: 265669]}  ali model 3D-neighbors follow..  33  1AAGDKEIPINGVRKAIAKHMSVSKQ-EIPHAWMMVEVDATGLVRYRNAVKDSFEEGYSLTYFAFFIKAVAQALKEFPQLNSTWAGDKIIEHANINISIAIAAGDLLYVPVIKNADEKSIKGIAREISELAGKARNGKLSQADMEGGTFTVNSTGSFGSVQSMGIINHPQAAILQVESIVKRPVIIDDMIA--------VRDMVNLCLSIDHRILDGLLAGKFLQAIKANVEKISKENT 231
2 -102.000d1scza_ c.43.1.1 (A:) Dihydrolipoamide succinyltransferase {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  32  1ARSEKRVPMTRLRKRVAERLLEAKN-STAMLTTFNEVNMKPIMDLRKQYGEAFEKGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVE--------ILPMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLL 231
3 -99.700d3l60a_ c.43.1.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  30  2....DVRPVHGVHARMAEKMTLSHK-EIPTAKASVEVICAELLRLRDRFV---SAAPEITPFALTLRLLVIALKHNVILNSTWEGPQVHVHRGVHLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVSNFGALGVDDGVPVINHPEAAILGLGAIKPRPVVVGGEVV--------ARPTMTLTCVFDHRVVDGAQVAQFMCELRDLIESPETALL 227
4 -92.400d1dpba_ c.43.1.1 (A:) Dihydrolipoamide acetyltransferase {Azotobacter vinelandii [TaxId: 354]}  ali model 3D-neighbors follow..  29  13.GEIEEVPMTRLMQIGATNLHRSWL-NVPHVTQFESADITELEAFRVAQKAVAEKGVKLTVLPLLLKACAYLLKELPDFNSSLAGQALIRKKYVHIGFAVDTPDGLLVPVIRNVDQKSLLQLAAEAAELAEKARSKKLGADAMQGACFTISSLGHIGGTAFTPIVNAPEVAILGVSKASMQPVWDGKAFQ--------PRLMLPLSLSYDCRVINGAAAARFTKRLGDLLADIRAILL 243
5 -89.400d2ii3a_ c.43.1.0 (A:) automated matches {Cow (Bos taurus) [TaxId: 9913]}  ali model 3D-neighbors follow..  26  1.GKDRTEPVKGFHKAMVKTMSAAL--KIPHFGYCDEVDLTELVKLREELKPIAFAGIKLSFMPFFLKAASLGLLQFPILNASVDCQNITYKASHNIGIAMDTEQGLIVPNVKNVQIRSIFEIATELNRLQKLGSAGQLSTNDLIGGTFTLSNIGSIGGTYAKPVILPPEVAIGALGTIKALPRFNEK-------GEVCKAQIMNVSWSADHRIIDGATVSRFSNLWKSYLENPAFMLL 231
6 -48.100d3claa_ c.43.1.1 (A:) Chloramphenicol acetyltransferase, CAT {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  8  2..NYTKFDVKNVRREHFEFY---RHRLPCGFSLTSKIDITTLKKSLDD--------SAYKFYPVMIYLIAQAVNQFDELRMAIKDDELIVWDSVDPQFTVFHQETETFSALSCPYSSDIDQFMVNYLSVMERYKSDTKLFPQGVTPENHLNISALPWVNFDSFNLNVANFTDYFAPIITMAKYQQEGD-----------RLLLPLSVQVHHAVCDGFHVARFINRLQELCNSKLK... 213
7 -47.600d2i9da_ c.43.1.0 (A:) automated matches {Bacteroides thetaiotaomicron [TaxId: 226186]}  ali model 3D-neighbors follow..  11  1...........MKQIIDIENWERKEFQNPQLSITSEVECGGARQRAKA--------AGQSFFLHYLYAVLRAANEIPEFRYRIDPDRVVLYDTIDMLSPIKIKENGKFFTTRFPYHNDFDTFYQEARLIIDAIPEDG-DPYAAENEEVADGDYGLILLSATPDLYFTSITGTQEKRSGNNYPLLNAGKAIIREG-----RLVMPIAMTIHHGFIDGHHLSLFYKKVEDFLK....... 214
8 -5.780d3h4oa_ d.90.1.0 (A:) automated matches {Clostridium difficile [TaxId: 272563]}  ali model 3D-neighbors follow..  8  1....................................MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIA----PTGGNRQPQRLIVIQEDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDHMMLQATELGL-------ASVWV---CYFNPDIIREEFSLPDINILLMGYESKIP........................................................ 150
9 -5.450d3t0ha_ d.122.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  9  8...................................QAEIAQLMSL---IINTFYSNKEIFLRELISNS-SDALDKIRYESLT-DPSKLDSGKELHINLIPNKQDRTLT-----IVDTGIGMTKADLNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESFTVRTDTGEPMGRGTKVILHLKEDQTYLEERRIKEIVKKHSQFIGYPITL.. 205
10 -5.380d3g14a_ d.90.1.0 (A:) automated matches {Clostridium novyi [TaxId: 386415]}  ali model 3D-neighbors follow..  13  1....................................MEFYEVIKKRKSIKKFEQTAIDRDKLLKIIDMAMRA----PSWNKTPYKFIVVESDKLKLDIANAIENKTIVAVANPEESGDVSGKEIYLIDTAIAMEHIVLGATDEGYGTCWI---AAFNENKIKEALKIPDVALTPLGVPKDSA........................................................ 157
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. VISSA: a program to visualize structural features from structure sequence alignment. Bioinformatics. 2006 Apr 1;22(7):887-8. Epub 2006 Jan 24.