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Query: PF02558.16; Q9K9R6_BACHD/6-154; Ketopantoate reductase PanE/ApbA, from PfamA32U

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst VAVIGSGSIGLLLYAYLKLANWPALLVTNRPEQADHLNKEGLTFVAKSGEHQPISVTATPLSSFSAEEAEVGFITVKSFAVKALLPQLQRKKWDGLVFFQNGMTHLEILRQIPARAICCGIVEIGAKRESDVRVQHTGDGAIWIGDMVGLast
1 -47.900d1yjqa2 c.2.1.6 (A:1-167) Ketopantoate reductase PanE {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  20  3ITVLGCGALGQLWLTALCKQGHEVQGWLRVPQP-----YCSVNLVETDGSIFNESLTANDPDF--LATSDLLLVTLKAWQVSDAVKSLASTVTTPILLIHNGMGTIEELQNI-QQPLLMGTTTHAARR-DGNVIIHVANGITHIGPARQ 144
2 -23.200d1bg6a2 c.2.1.6 (A:4-187) N-(1-D-carboxylethyl)-L-norvaline dehydrogenase {Arthrobacter, strain 1c [TaxId: 1663]}  ali model 3D-neighbors follow..  16  4YAVLGLGNGGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAHPDLLTSDGLAVKDADVILIVVPAIHHASIAANIASYEGQLIILNPGATGGAKILRENGAPEVTIGSMLFTCRSERPGQVTVNA........... 151
3 -22.400d3k96a1 c.2.1.0 (A:3-180) automated matches {Coxiella burnetii [TaxId: 227377]}  ali model 3D-neighbors follow..  20  6IAILGAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGVNNRYLPNYPFPETLKAYCDLKASLEGVTDILIVVPSFAFHEVITRMKPLAKTRIAWGTKGL.............................................. 110
4 -21.500d1evya2 c.2.1.6 (A:9-197) Glycerol-3- phosphate dehydrogenase {Trypanosome (Leishmania mexicana) [TaxId: 5665]}  ali model 3D-neighbors follow..  15  10AVVFGSGAFGTALAMVLSKKCREVCVWHMNEEEVRLVNEKRENVLFLKGVQLASNITFTSDVEKAYNGAEIILFVIPTQFLRGFFEKSGGNKQVPVLVCTKGI.............................................. 119
5 -18.600d1z82a1 c.2.1.0 (A:2-166) automated matches {Thermotoga maritima [TaxId: 243274]}  ali model 3D-neighbors follow..  16  4FFVLGAGSWGTVFAQMLHENGEEVILWARRKEIVDLINVSESKIT-----------VRATNDLEEIKKEDILVIAIPVQYIREHLLRLPV-KPSMVLNLSKGI.............................................. 101
6 -18.600d1txga2 c.2.1.6 (A:1-180) Glycerol-3- phosphate dehydrogenase {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  10  3VSILGAGAMGSALSVPLVDNGNEVRIWGTETEILKSISAGREHPRLGVK-LNGVEIFWPEQLEKCLENAEVVLLGVSTDGVLPVMSRILPYDQYIVLISKGLIDFDNSVLTVPEWRLKHDLRERTVAITGPAIAREVAKR......... 147
7 -18.400d1x0va1 c.2.1.0 (A:2-193) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  5VCIVGSGNWGSAIAKIVGGNDPRVTMWVFEEDLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHANATGISLIKGVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEK........ 159
8 -17.300d2ahra2 c.2.1.6 (A:1-152) Pyrroline-5-carboxylate reductase ProC {Streptococcus pyogenes [TaxId: 1314]}  ali model 3D-neighbors follow..  9  3IGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQ-------------LALPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLH--FKQPIISMAAGISLQRLATFVGQDLPLLRIMPNMNAQILQSST............... 121
9 -16.500d2i76a2 c.2.1.6 (A:2-154) Hypothetical protein TM1727 {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  16  2LNFVGTGTLTRFFLECLKDRYEIGYILSRSIDRARNLAEVY---------------GKAATLEKHPELNGVVFVIVPDRYIKTVANHLN--LGDAVLVHCSGFLSSEIFKKSGRASI................................ 102
10 -15.800d3fr7a1 c.2.1.0 (A:86-307) automated matches {Oryza sativa [TaxId: 39947]}  ali model 3D-neighbors follow..  13  43IGVIGWGSQGPAQAQNLRDSLAEAKS---DIVVKIGLRKGSKSFDEARAAGFTEESGTLGDIWETVSGSDLVLLLISDAAQADNYEKIFSMKPNSILGLSHGFL............................................. 144
11 -15.600d5bsea1 c.2.1.0 (A:3-169) automated matches {Medicago truncatula [TaxId: 3880]}  ali model 3D-neighbors follow..  13  11LGFIGAGKMAESIAKGAVRSGSRIKTAIHSNPARRTAFES-------------IGITVLSSNDDVVRDSNVVVFSVKPQLLKDVVLKLKPLKDKLLVSVAAGIKMKDLQEWAGHERFI---------RVMPNTAATVGEAASVM..... 138
12 -15.500d1xc2a3 c.2.1.6 (A:1-152) Pyrroline-5-carboxylate reductase ProC {Neisseria meningitidis, serogroup B [TaxId: 487]}  ali model 3D-neighbors follow..  13  3VYFLGGGNMAAVAGGLVKQGGYRIYIANRGAEKRERLEKEGVETSA---------------TLPELHSDDVLILAVKPQDMEAACKNIRT-NGALVLSVAAGLSVGTLSRYLGGTRRIVRVMPNTPGKIGLGVS............... 122
13 -15.400d1jaya_ c.2.1.6 (A:) Coenzyme F420H2:NADP+ oxidoreductase (FNO) {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  14  3VALLGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYRRIAGDASITGMKNEDAA-------EACDIAVLTIPWEHAIDTARDLKNILREKIVVSSERSAAEIVAEVLESEKVVSALHTIPAARFAN.................. 142
14 -15.300d2f1ka2 c.2.1.6 (A:1-165) Prephenate dehydrogenase TyrA {Synechocystis sp. PCC 6803 [TaxId: 1148]}  ali model 3D-neighbors follow..  14  3IGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCEKAVERQL-------------VDEAGQDLSLLQTAKIIFLCTPIQLILPTLEKLIPHLSPTAIVTDVASVKTAIAEPASQ................................... 103
15 -15.000d1i36a2 c.2.1.6 (A:1-152) Conserved hypothetical protein MTH1747 {Methanobacterium thermoautotrophicum [TaxId: 145262]}  ali model 3D-neighbors follow..  13  3VGFIGFGEVAQTLASRLRSRGVEVVTSLEGRSPSTIERARTVGVTE--------------TSEEDVYSCPVVISAVTPGVALGAARRAGRHVRGIYVDINNGFVDAAIMGSVRRKGADIRIIASGRDAEEFMKLNRYGLNIEVRGR... 150
16 -14.800d1lssa_ c.2.1.9 (A:) Ktn Mja218 {Methanococcus jannaschii [TaxId: 2190]}  ali model 3D-neighbors follow..  12  3IIIAGIGRVGYTLAKSLSEKGHDIVLIDIDKDICKKASAE-IDALVINGDCTKIKT----LEDAGIEDADMYIAVTGKEEVNLMSSLLAKSYGINTIARISEIEYKDVFERLGVDVVV............................... 116
17 -14.500d3tria1 c.2.1.0 (A:2-162) automated matches {Coxiella burnetii [TaxId: 777]}  ali model 3D-neighbors follow..  13  5ITFIGGGNMARNIVVGLIANGNRICVTNRSLDKLDFFKEK-------------CGVHTTQDNRQGALNADVVVLAVKPHQIKMVCEELKDITKILVISLAVGVTTPLIEKWLGKASRIVRAMPNTPSSVRAGAT............... 131
18 -14.400d1dlja2 c.2.1.6 (A:1-196) UDP-glucose dehydrogenase (UDPGDH) {Streptococcus pyogenes [TaxId: 1314]}  ali model 3D-neighbors follow..  16  3IAVAGSGYVGLSLGVLLSL-QNEVTIVDILPSKVDKINNGLSPIQDEEYYLKSKQLSIKATLDSKAAYKEAELVIIATQHVETVIKEVLSVNSHATLIIKSTI.............................................. 119
19 -14.200d1mv8a2 c.2.1.6 (A:1-202) GDP-mannose 6-dehydrogenase {Pseudomonas aeruginosa [TaxId: 287]}  ali model 3D-neighbors follow..  15  3ISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPQQGRQTGRLSGTTDFKKAVLDSDVSFICVGTTVCREIGFAIREKSERHTVVVRSTV.............................................. 125
20 -14.000d4ypoa1 c.2.1.0 (A:1-180) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  18  17VGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQ----------------DVDTPAEVAKWADVVMVLAPDTAQAEIFDIEPNLKPGDALFFGHGLN............................................. 108
21 -14.000d4e12a1 c.2.1.0 (A:1-189) automated matches {Acinetobacter baylyi [TaxId: 202950]}  ali model 3D-neighbors follow..  9  7VTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKR--GAADGAAQKALGGIRYSDDLAQAVKDADLVIEAVPE---RDIYTKLGELAPAKTIFATNTLLPSDLVGYTGRGDKFLAL............................ 142
22 -13.900d1mo9a2 c.3.1.5 (A:193-313) NADH-dependent 2-ketopropyl coenzyme M oxidoreductase/carboxylase {Xanthobacter sp., py2 [TaxId: 35809]}  ali model 3D-neighbors follow..  11  25VVVVGGSKTAVEYGCFFNATGRRTVMLVRTEP-LDRMKEQGMEIIEEDANGRVQAVVAMTPNGEMRIETDFVFLGL......................................................................... 120
23 -13.800d4dlla1 c.2.1.0 (A:29-190) automated matches {Polaromonas sp. [TaxId: 296591]}  ali model 3D-neighbors follow..  19  6ITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALG--------------ATIHEQARAAARDADIVVSMLENGAVVQDVQGVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVSGGTVGAEQGTLVIMAG.... 139
24 -13.700d2g1ua_ c.2.1.0 (A:) automated matches {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  15  7IVIFGCGRLGSLIANLASSSGHSVVVVDKNEYAFHRLNSEGFTVVGDAAEFETLK-------ECGMEKADMVFAFTNDDSTNFFISMNARYMFNVVIARVYDPEKIKIFEENGIKTI................................ 120
25 -13.700d2rcya1 c.2.1.0 (A:2-156) automated matches {Plasmodium falciparum [TaxId: 36329]}  ali model 3D-neighbors follow..  13  6LGFMGLGQMGSALAHGIANAN--------------IIKKENLFYYGPSKKN--TTLNYMSSNEELARHCDIIVCAVKPDIAGSVLNNIKPLSSKLLISICGGLNIGKLEEMVGSENKIVWVMPNTPCLVGEGSF............... 124
26 -13.700d2hmta_ c.2.1.9 (A:) Ktn bsu222 {Bacillus subtilis [TaxId: 1423]}  ali model 3D-neighbors follow..  18  4FAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATEENE------LLSLGIRNFEYVIVAINIQASTLTTLLLKELDIPNIWVKAQNYYHHKVLEKIGADRII............................... 117
27 -13.500d1nhpa1 c.3.1.5 (A:1-119,A:243-321) NADH peroxidase {Enterococcus faecalis [TaxId: 1351]}  ali model 3D-neighbors follow..  13  3VIVLGSSHGGYEAVEELLNLHPDAEIQWYEKGDFEKMESRGVNVTAIQPKEHQVTVKDLVSGEERVENYDKLIISPGAVPFELDXGVRPNLKGTLELHPNGLIKTDEYMRTSEPDVFAVG............................. 158
28 -13.500d2uyya1 c.2.1.0 (A:262-429) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  11  9IGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEG--------------ARLGRTPAEVVSTCDITFACVSDPKAAKDLSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAA.... 143
29 -13.400d4gwga1 c.2.1.0 (A:1-176) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  12  5IALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRR-----IILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGN... 145
30 -13.400d1onfa2 c.3.1.5 (A:154-270) Glutathione reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}  ali model 3D-neighbors follow..  13  25IGIVGSGYIAVELINVIKRLGIDSYIFARGNRILNDMKKNNINIVTFADVVEIKKLSIHLSDGRIYEHFDHVIYCV......................................................................... 117
31 -13.300d2izza1 c.2.1.0 (A:1-164) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  3VGFIGAGQLAFALAKGFTAAGHKIMASSPDMDLATVSALRKM------------GVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADDRHIVVSCAAGVTISSIEKKLSAFRPAPRVI-----RCMTNTPVVVREGATVY..... 135
32 -13.200d2g5ca2 c.2.1.6 (A:30-200) Prephenate dehydrogenase TyrA {Aquifex aeolicus [TaxId: 63363]}  ali model 3D-neighbors follow..  11  4VLIVGVGFMGGSFAKSLRRSGGKIYGYDINPESISKAVDLGI-----------IDEGTTSIAKVEDFSPDFVMLSSPVRTFREIAKKLSYILSEDATVTDQGSVKGKLVYDLEN................................... 108
33 -13.200d1e5qa1 c.2.1.3 (A:2-124,A:392-450) Saccharopine reductase {Fungus (Magnaporthe grisea) [TaxId: 148305]}  ali model 3D-neighbors follow..  11  5VLMLGSGFVTRPTLDVLTDSGIKVTVACRTLESAKKLSAG------QHSTPISLDVNDDAALDAEVAKHDLVISLIPYTFHATVIKSAIRQKKHVVTT-----YVSPAMMELDQAAKDAGITVMNEIGXYSA................. 127
34 -13.100d3lada2 c.3.1.5 (A:159-277) Dihydrolipoamide dehydrogenase {Azotobacter vinelandii [TaxId: 354]}  ali model 3D-neighbors follow..  18  25LGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLKILTKQGLRVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAV......................................................................... 118
35 -13.000d1li4a1 c.2.1.4 (A:190-352) S-adenosylhomocystein hydrolase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  13  27AVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTM---------------DEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRVNLGCAMG 163
36 -12.900d1h6va2 c.3.1.5 (A:171-292) Mammalian thioredoxin reductase {Norway rat (Rattus norvegicus) [TaxId: 10116]}  ali model 3D-neighbors follow..  14  23TLVVGASYVALECAGFLAGIGLDVTVMVRSNKIGEHMEEHGIKFEAGTPGRLKVTAKSTNSEETIEDEFNTVLLAV......................................................................... 121
37 -12.900d1lvla2 c.3.1.5 (A:151-265) Dihydrolipoamide dehydrogenase {Pseudomonas putida [TaxId: 303]}  ali model 3D-neighbors follow..  21  24LVVVGGGYIGLELGIAYRKLGAQVSVVEARERILESLKKLGIALHSVEGYENGCLLANDGKGGQLRLEADRVLVAV......................................................................... 114
38 -12.900d3g0oa1 c.2.1.0 (A:6-169) automated matches {Salmonella typhimurium [TaxId: 602]}  ali model 3D-neighbors follow..  14  4VGIVGLGSMGMGAARSCLRAGLSTWGADLNPQACANLLAEG-------------ACGAAASAREFAGVVDALVILVVNAAQVRQVDGVAHLMKPGSAVMVSSTISSADAQEIAAALTALNLNMLDAPVSGGAVKAAQGEMTVMAS.... 139
39 -12.800d1ebda2 c.3.1.5 (A:155-271) Dihydrolipoamide dehydrogenase {Bacillus stearothermophilus [TaxId: 1422]}  ali model 3D-neighbors follow..  20  25LVVIGGGYIGIELGTAYANFGTKVTILEGAGEILKRLKKKGVEVKGAEEREDGVTVTYEANGETKTIDADYVLVT.......................................................................... 117
40 -12.800d3u95a1 c.2.1.0 (A:1-191) automated matches {Thermotoga neapolitana [TaxId: 309803]}  ali model 3D-neighbors follow..  12  3ISIVGAGSVRIAQTDELSREDTHIYLMDVHERRLNASYILARKYVEELN--SPVKVVKTESLDEAIEGADFIINTAYPYDPRYHDSGSQRWDEVTKV-YYRGIDSQELNMVSTYTYVLSSYPDVKLALEIAEKMKKMAPKAYLMQTAN. 160
41 -12.800d1f0ya2 c.2.1.6 (A:12-203) Short chain L-3-hydroxyacyl CoA dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  7VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVE---NELFKRLDKFAAEHTIFASNSLQITSIANATTRQDRFAGL............................ 146
42 -12.700d3ws7a1 c.2.1.0 (A:1-161) automated matches {Pyrobaculum calidifontis [TaxId: 410359]}  ali model 3D-neighbors follow..  17  3VGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAG--------------VYVAESPADLAKRVDVVIVMVSDAPDVEQVSGVVEGARPGLIVVDMSTNSPDWARKFAERLAQYGIEFLDAPVTGGQKGAIEGTLTIMVG.... 137
43 -12.500d5je8a1 c.2.1.0 (A:1-163) automated matches {Bacillus cereus [TaxId: 226900]}  ali model 3D-neighbors follow..  18  4IGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEG--------------GIIGLSISKLAETCDVVFTSLPSPRAVEAVEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAPVSGGVIGAENRTLTFMVG.... 138
44 -12.500d2gf2a1 c.2.1.0 (A:41-201) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  2VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAG--------------EQVVSSPADVAEKADRIITMLPTSINAIEANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVG.... 136
45 -12.300d1v59a2 c.3.1.5 (A:161-282) Dihydrolipoamide dehydrogenase {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  26  26LTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGKFLKKQGLDFRNDDKNVVEIVVEDTKTNKQENLEAEVLLVA.......................................................................... 122
46 -12.100d1xhca1 c.3.1.5 (A:2-103,A:226-289) NADH oxidase /nitrite reductase {Pyrococcus furiosus [TaxId: 2261]}  ali model 3D-neighbors follow..  10  2VVIVGNGPGGFELAKQLSQ-TYEVTVIDKEPVSLDWYRKRGIEIRLAEEAKLIDRGRKVVITEKGEVPYDTLVLATGAXPNVDLARRSG-------IHTGRGILIDDNFRTSAKDVYAIGDCAEYSGIIAGTAKAAMEQARVLADILKG 166
47 -11.700d1an9a1 c.4.1.2 (A:1-194,A:288-340) D-aminoacid oxidase, N-terminal domain {Pig (Sus scrofa) [TaxId: 9823]}  ali model 3D-neighbors follow..  27  3VVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPF............................................................................................................. 42
48 -11.700d2cvza2 c.2.1.6 (A:2-157) Hydroxyisobutyrate dehydrogenase {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  18  3VAFIGLGAMGYPMAGHLARRFPTL-VWNRTFEKALRHQEEF---------------GSEAVPLERVAEARVIFTCLTTREVYEVAEALYPYLREGTYWVDATSGEPEASRRLAERLREKGVTYLDAPVSGGTSGAEAGTLTVMLG.... 132
49 -11.700d1c0pa1 c.4.1.2 (A:1001-1193,A:1289-1361) D-aminoacid oxidase, N-terminal domain {Rhodotorula gracilis [TaxId: 5286]}  ali model 3D-neighbors follow..  30  7VVVLGSGVIGLSSALILARKGYSVHILARD....................................................................................................................... 36
50 -11.700d1xhca2 c.3.1.5 (A:104-225) NADH oxidase /nitrite reductase {Pyrococcus furiosus [TaxId: 2261]}  ali model 3D-neighbors follow..  25  35AIIIGGGFIGLELAGNLAEAGYHVKLIHRGAMFLDMLEETGVKFFLNSELLEANEEGVLTNSGFI--EGKVKICAI......................................................................... 119
51 -11.600d1hdoa_ c.2.1.2 (A:) Biliverdin IX beta reductase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  9  6IAIFGAGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGD-------VLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAGVDKVVACTSAF.................................... 113
52 -11.600d2pv7a2 c.2.1.6 (A:92-243) Prephenate dehydrogenase TyrA {Haemophilus influenzae [TaxId: 727]}  ali model 3D-neighbors follow..  15  12IVIVGGGKLGGLFARYLRASGYPISILDREDW---------------------------AVAESILANADVVIVSVPINLTLETIERLKPYLTENMLLADLTSVKREPLAKM..................................... 97
53 -11.600d4j0ea1 c.2.1.0 (A:1-198) automated matches {Nematode (Caenorhabditis elegans) [TaxId: 6239]}  ali model 3D-neighbors follow..  14  14VAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRSKKQKGTDKEKSDTLTMSRIKTCNNVSTAVADADLIIEAAIE---RGIFAQIEQSCKKDSILTTNSFLLEDVAKGLQDKTRFGGL............................ 152
54 -11.500d3dk9a2 c.3.1.5 (A:166-290) Glutathione reductase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  10  25SVIVGAGYIAVEMAGILSALGSKTSLMIRHDK-TEELENAGVEVLKFSQVKEVKKTLGRLPVMTMIPDVDCLLWAI......................................................................... 124
55 -11.500d1nhpa2 c.3.1.5 (A:120-242) NADH peroxidase {Enterococcus faecalis [TaxId: 1351]}  ali model 3D-neighbors follow..  17  33VVVIGSGYIGIEAAEAFAKAGKKVTVIDILDRPLEEMEANNITIATGETVERYEGDGRVQVTDKNAYDADLVVVAV......................................................................... 123
56 -11.500d1i8ta1 c.4.1.3 (A:1-244,A:314-367) UDP-galactopyranose mutase, N-terminal domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  24  4YIIVGSGLFGAVCANELKKLNKKVLVIEKRNHNAYTEDCEGIQIHKYGAH................................................................................................... 56
57 -11.400d2gqwa1 c.3.1.5 (A:6-115,A:237-308) NADH-dependent ferredoxin reductase, BphA4 {Pseudomonas sp., KKS102 [TaxId: 306]}  ali model 3D-neighbors follow..  13  5VVVLGAGLASVSFVAELRQAGYQGLITVVGDE-LDCKRAPEVEWLGVTAQSFDPQAHTVALSDGRTLPYGTLVLATGAAPRAXVLAN-DALARAAGLACDDGIFVDAYGRTTCPDVYALGDVTRQRNPLSGRFER.............. 162
58 -11.400d1fcda1 c.3.1.5 (A:1-114,A:256-327) Flavocytochrome c sulfide dehydrogenase, FCSD, flavin-binding subunit {Chromatium vinosum [TaxId: 1049]}  ali model 3D-neighbors follow..  19  5VVVVGGGTGGATAAKYIKLADIEVTLIEPNTDYYDGLRAHGIQVVHDSATGIDPDKKLVKTAGGAEFGYDRCVVAP......................................................................... 104
59 -11.300d4m1qa1 c.2.1.0 (A:3-144) automated matches {Bacillus selenitireducens [TaxId: 439292]}  ali model 3D-neighbors follow..  14  6VVIIGTGAVGSSYAFSMINQNDEMVLIDLDKRKTE-----GDAMDLNHGIPFGAPTKVWAGDYGDCKSADIVVITANANIFKGIVDQVMGSFNGIFIIATNPVDVLAYASGLPKERVIG.............................. 142
60 -11.100d1t2da1 c.2.1.5 (A:1-150) Lactate dehydrogenase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}  ali model 3D-neighbors follow..  12  6IVLVGSGMIGGVMATLIVQKNGDVVLFDIVKNMPHG---KALDTSHTNVMAYSNCKVSGSNTYDDLAGADVVIVTANNKIMIEIGGHIKKNPNAFIIVVTNPVDVMVQLSGVPKNKIIG.............................. 148
61 -11.100d2voua1 c.3.1.2 (A:2-163,A:292-394) Dihydroxypyridine hydroxylase DhpH {Arthrobacter nicotinovorans [TaxId: 29320]}  ali model 3D-neighbors follow..  13  7IAVVGGSISGLTAALMLRDAGVDVDVYERSPQPLSGF---GTGIVVQPELVHYLLEQGVELDSISVPSSSMEYVDALTGERVGSV-------PADWRFTSYDSIYGGLYELFGPERYHTSKCLVGLSQDSETVQMRFSDGTKAEANW.. 143
62 -11.000d1q1ra1 c.3.1.5 (A:2-114,A:248-319) Putidaredoxin reductase {Pseudomonas putida [TaxId: 303]}  ali model 3D-neighbors follow..  12  6VVIVGTGLAGVEVAFGLRASGWEGNIRLVGDATPDAYAAQNIQLLGTQVTAINRDRQQVILSDGRALDYDRLVLATGGRPXLIPNCELASAAG---LQVDNGIVINEHMQTSDPLIMAVG............................. 150
63 -11.000d2bi7a1 c.4.1.3 (A:2-247,A:317-384) UDP-galactopyranose mutase, N-terminal domain {Klebsiella pneumoniae [TaxId: 573]}  ali model 3D-neighbors follow..  15  5ILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDH..................................................................................................................... 36
64 -11.000d1o94a3 c.4.1.1 (A:341-489,A:646-729) Trimethylamine dehydrogenase, middle domain {Methylophilus methylotrophus, w3a1 [TaxId: 17]}  ali model 3D-neighbors follow..  12  52VLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHLNQVAALLKKNKESQLALGQKPMTADDVLQYGADKVIIATGAXSECTLWNELK---ARESEWAENDIKGIYLIGDAEAPRLIADATFTG........................ 193
65 -11.000d2v6ba1 c.2.1.0 (A:22-164) automated matches {Deinococcus radiodurans [TaxId: 1299]}  ali model 3D-neighbors follow..  18  3VGVVGTGFVGSTAAFALVLRGSELVLVDRDEDRAQ-----AEAEDIAHAAPVSHGTRVWHGGHSELADAQVVILTANADIFRELVPQITRAPDAVLLVTSNPVDLLTDLQLAPGQPVIG.............................. 137
66 -10.900d3nepx1 c.2.1.0 (X:22-163) automated matches {Salinibacter ruber [TaxId: 309807]}  ali model 3D-neighbors follow..  15  3VTVIGAGNVGATVAECVARQDKEVVMVDIKDGMPQG---KALDMRESSPIHGFDTRVTGTNDYGPTEDSDVCIITANTEIVGGVTEQFVEGPDSTIIVVANPLDVMTYVSGFPTNRVMG.............................. 141
67 -10.900d2gqfa1 c.3.1.8 (A:1-194,A:343-401) Hypothetical protein HI0933 {Haemophilus influenzae [TaxId: 727]}  ali model 3D-neighbors follow..  21  7NIIIGAGAAGLFCAAQLAKLGKSVTVFDNGKKIGRKILMSG............................................................................................................ 47
68 -10.900d1ojta2 c.3.1.5 (A:276-400) Dihydrolipoamide dehydrogenase {Neisseria meningitidis [TaxId: 487]}  ali model 3D-neighbors follow..  12  29LLIIGGGIIGLEMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYRFDNIMVNTKTVAVEPKEDGVYVTFEGAN..................................................................... 108
69 -10.800d1nvmb1 c.2.1.3 (B:1-131,B:287-312) Acetaldehyde dehydrogenase (acylating) {Pseudomonas sp. [TaxId: 306]}  ali model 3D-neighbors follow..  16  7VAIIGSGNIGTDLMIKVLRNAKYLEMGAMVGIDAA---SDGLARAQRMGVTTTYAGVEGLIKLPEFADIDFVFDATSASAHVQNEALLRQAKPGIRLIDLTPAA............................................. 107
70 -10.700d2gqwa2 c.3.1.5 (A:116-236) NADH-dependent ferredoxin reductase, BphA4 {Pseudomonas sp., KKS102 [TaxId: 306]}  ali model 3D-neighbors follow..  18  33LLIVGGGVIGLELAATARTAGVHVSLVETQPRLMSRAAAQGVDLR-FERSVTGSVDGVVLLDDGTRIAADMVVVGI......................................................................... 120
71 -10.700d1d7la1 c.3.1.2 (A:1-173,A:276-394) p-Hydroxybenzoate hydroxylase, PHBH {Pseudomonas aeruginosa [TaxId: 287]}  ali model 3D-neighbors follow..  33  5VAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDVDLLREAGV........................................................................................................... 61
72 -10.700d2r6ja_ c.2.1.0 (A:) automated matches {Ocimum basilicum [TaxId: 39350]}  ali model 3D-neighbors follow..  14  6ILIFGGGYIGNHMVKGSLKLGHPTYVFTRPNSSLDEFQSLGAIIVKGELDEHEKLVELM-------KKVDVVISALAFPQILDQFKILEAIKVAGNI.................................................... 100
73 -10.700d1feca2 c.3.1.5 (A:170-286) Trypanothione reductase {Crithidia fasciculata [TaxId: 5656]}  ali model 3D-neighbors follow..  11  21ALCVGGGYISIEFAGIYKARGGQVDLAYRGDM-TEQLRANGINVRTHENPAKVTKTRHVVFESGAEADYDVVMLAI......................................................................... 115
74 -10.600d3keoa2 c.2.1.0 (A:82-212) automated matches {Streptococcus agalactiae [TaxId: 216495]}  ali model 3D-neighbors follow..  17  6VMLVGCGNIGRALLHYRFHDRNKMQISMAFDLDSNDLVGDGIPVYGISTINDHLI----------DSDIETAILTVPSTEAQEVADILVKAGIKGIL.................................................... 96
75 -10.500d3i6ia_ c.2.1.0 (A:) automated matches {Grape (Vitis vinifera) [TaxId: 29760]}  ali model 3D-neighbors follow..  15  3VLIAGAGFIGQFVATASLDAHRPTYILARPGPRFKALEDKGAIIVYGLINEQEAMEKILKEHE-----IDIVVSTVGGESILDQIALVKAMKAVGTI.................................................... 102
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.