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Query: PF00208.21; DHE3_ORYSJ/176-408; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase, from PfamA32U

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst GGSLGRDAATGRGVMYATEALLTEYSESISGSTFVIQGLGNVGSWAAKLIHQKGGKIVAVGDVTGAIRNKSGIDIPALLKHRSEGGSLEDFYGAEVMDAAELLVHECDVLVPCALGGVLNRENAAEVKARFIIEGANHPTDTEADEILAKKGVIVLPDIYANSGGVVVSYFEWVQNIQGFMWDEEKVNRELQKYMKNAFQNIKDMCKSQNCNLRMGAFTLGVNRVAKATLLRGLast
1 -76.700[E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase  ali follow..  40  181GGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNL-FEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRG 412
2 -68.200[E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases  ali follow..  35  263GGIHGRISATGRGVFHGIENFINQASPGFRDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAK-PYEGSILEVDCDILIPAATEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLERNILVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLLSVQESLERKFGLDLRTAAYVNAIEKVFKVYSEAG 554
3 -19.000[E] COG2902 NAD-specific glutamate dehydrogenase  ali follow..  19  925GGSAGKMGITARGAWETVKRHFREMDTDIQTTPFTVAGVGDMSGDVFGMLLSEKIRLIAAFDHRDIFIDPDPDTDKSFAERKRPRSSWQDYDRSTLSAGAMIISRSIGTYIKAAVENDPIRVNATELRAKVIGEGANLGITQKGRIAYALAGGRCNSDAIDNSAGVNSSDVELASAVNSGRLTMPKRNQLLASMTPDVAQLVLRNNYQQSLAILGLANREELGRLMGALEATG 1229
4 -10.300[C] COG0281 Malic enzyme  ali follow..  13  164.......HGTAIISAAAIINSLRIVGKKIEDVRLVASGAGAASIACLNLLLSLGMKRENI------VCDSKGVVYKGRDDKMDQTKKEYAIEDNGWRKLADAIP-NADIFLGCSAAGALTQDMVKSMAAHPIILALANPNTGRSDYPNQVNNVLCFPFIFRGA-EMKRAAVYAIADLALEEQNEVVTSAYGGEGATFGADYVIPRPFDPRLIVRIAP------AVAKAAMESG 404
5 -9.710[R] COG1712 Predicted dinucleotide-utilizing enzyme  ali follow..  16  2...............................LKIGIVGCGFIGGQICRAIDGGSAELYALCD----------SSESKALELAASLKT-----CKPSYMKIEELIRGVDLIIESASQNAVRFIVPQALKADVMILSVGALADEELRDTLFG................................................................................... 109
6 -9.150[R] COG2085 Predicted dinucleotide-binding enzymes  ali follow..  20  1..........................MSHTKPSIAILGAGRVGSSLARSAVAAGYEVKVAGSGAV----------------DKIALTAEILMPGAVPSTADQAVKDADIVFLAVPLHKFRSVNPATLEGKIVIDTMN................................................................................................ 95
7 -8.960[H] COG0499 S-adenosylhomocysteine hydrolase  ali follow..  15  244................LIDGINRATDMLMGGKNVLVCGYGDVGKGCAEAFDGQGARVKVTE-----------ADPINALQALMD--------GYSVVTVDEAIEDADIVITATGNKDIISFEQMLKMKDHALLGNIGH............................................................................................... 346
8 -8.720[R] COG5322 Predicted dehydrogenase  ali follow..  9  139......NSLTAYAAYRNVLESMDRLGVEPADTEVAVVGYGSIALVIAKLLAGHGCRLCLVHRGSE----------AQGRQGLAYLPEPMHAQVRLSNDIEHCYEHVQFYVAATSTGGLIDPYRLR--PGSVVVDAAKPYRKDRNDILIIDGGLVSASS-LAPKKFLNGCLAETLILGLEGRAEAFSIGRELPEDKVLEIGRIAELHGFSPSPMASYGEPVKDRHFAALRPF.. 366
9 -8.540[H] COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)  ali follow..  8  9...........................DLTNKPVLVVGGGEVACRKIDALLRADAKVTVIS--------------PQVAPALQAWIEQGKCHWIQHFYSSHWLDKRYVQVWATTDNPELNHQVYKDAKEQILVNVVDDQ----------PYCDFITPSMI-ERGRIQLA----ISSGGASPVLIRNIRETLEAVLAQNLALLADFGASKRNSIKDFLPSVDLRR......... 177
10 -8.450[K] KOG0067 Transcription factor CtBP  ali follow..  18  175.........................AARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFT-FLVNAARGGLVDEKAAQALKEGRIRGAASEPFSFAQGPLKDAPNLICTPHTAWYS...................................................................... 326
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Godzik A., Rychlewski L. A support vector machine approach to the identification of phosphorylation sites. Cell Mol Biol Lett. 2005;10(1):73-89.